Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO15A DNAH5 DNAI1

2.85e-04118223GO:0003774
GeneOntologyMolecularFunctionfibroblast growth factor binding

PTPRZ1 FGFR1

4.00e-0427222GO:0017134
GeneOntologyBiologicalProcessepithelial cilium movement involved in extracellular fluid movement

ADCY10 DNAH5 DNAI1

3.29e-0559223GO:0003351
GeneOntologyBiologicalProcessextracellular transport

ADCY10 DNAH5 DNAI1

3.82e-0562223GO:0006858
GeneOntologyCellularComponentouter dynein arm

DNAH5 DNAI1

6.93e-0512222GO:0036157
GeneOntologyCellularComponentaxonemal dynein complex

DNAH5 DNAI1

3.13e-0425222GO:0005858
MousePhenoabdominal situs inversus

DNAH5 DNAI1

4.40e-059162MP:0011249
MousePhenolung situs inversus

DNAH5 DNAI1

1.11e-0414162MP:0010854
MousePhenoabdominal situs ambiguus

DNAH5 DNAI1

1.46e-0416162MP:0011250
MousePhenoimmotile respiratory cilia

DNAH5 DNAI1

1.65e-0417162MP:0011649
MousePhenoabdominal situs abnormality

DNAH5 DNAI1

2.55e-0421162MP:0031284
MousePhenositus inversus totalis

DNAH5 DNAI1

3.06e-0423162MP:0011252
MousePhenodecreased somite size

FGFR1 HUWE1

4.56e-0428162MP:0011732
MousePhenoshort snout

DNAH5 DNAI1 FGFR1

4.60e-04136163MP:0000445
MousePhenoabnormal respiratory motile cilium physiology

DNAH5 DNAI1

4.90e-0429162MP:0011055
MousePhenoabnormal respiratory motile cilium morphology

DNAH5 DNAI1

4.90e-0429162MP:0011050
MousePhenosmall snout

DNAH5 DNAI1 FGFR1

5.43e-04144163MP:0030190
MousePhenoleft pulmonary isomerism

DNAH5 DNAI1

5.60e-0431162MP:0003178
MousePhenoincreased susceptibility to otitis media

DNAH5 FGFR1

5.60e-0431162MP:0001850
MousePhenodual inferior vena cava

DNAH5 DNAI1

6.74e-0434162MP:0011683
MousePhenoleft-sided isomerism

DNAH5 DNAI1

6.74e-0434162MP:0000542
MousePhenoabnormal somite size

FGFR1 HUWE1

7.56e-0436162MP:0005222
MousePhenoear inflammation

DNAH5 FGFR1

9.34e-0440162MP:0001849
MousePhenoheart right ventricle hypertrophy

ADA DNAH5

1.03e-0342162MP:0000276
MousePhenoabnormal inner hair cell stereociliary bundle morphology

MYO15A FGFR1

1.18e-0345162MP:0004532
MousePhenoabnormal right lung morphology

DNAH5 DNAI1

1.29e-0347162MP:0009570
MousePhenoabnormal motile cilium physiology

DNAH5 DNAI1

1.52e-0351162MP:0013209
MousePhenodextrocardia

DNAH5 DNAI1

1.52e-0351162MP:0000644
MousePhenoabnormal respiratory epithelium physiology

DNAH5 DNAI1

1.52e-0351162MP:0014200
MousePhenoabnormal heart right ventricle wall morphology

ADA DNAH5

1.58e-0352162MP:0031534
MousePhenoabnormal cilium physiology

DNAH5 DNAI1

1.64e-0353162MP:0013208
MousePhenodecreased cochlear hair cell number

MYO15A FGFR1

1.64e-0353162MP:0004408
MousePhenoincreased heart right ventricle size

ADA DNAH5

1.76e-0355162MP:0010563
MousePhenoimpaired coordination

MYO15A UBR1 PTPRZ1 FUCA1

1.77e-03478164MP:0001405
MousePhenoabnormal lung position or orientation

DNAH5 DNAI1

1.89e-0357162MP:0010853
MousePhenoabnormal cardiac muscle tissue morphology

ADA DNAH5 PLPP7 FGFR1

1.93e-03489164MP:0010630
MousePhenositus inversus

DNAH5 DNAI1

2.09e-0360162MP:0002766
MousePhenoabnormal inferior vena cava morphology

DNAH5 DNAI1

2.68e-0368162MP:0006063
MousePhenomicrognathia

DNAH5 DNAI1

2.68e-0368162MP:0002639
MousePhenoabnormal cochlear hair cell number

MYO15A FGFR1

2.68e-0368162MP:0004406
MousePhenoabnormal snout morphology

DNAH5 DNAI1 FGFR1

2.88e-03257163MP:0000443
MousePhenoabnormal heart position or orientation

DNAH5 DNAI1

3.16e-0374162MP:0006065
MousePhenoabnormal circulating total protein level

ADA DNAH5 UBR1

3.28e-03269163MP:0011888
MousePhenoabnormal CNS glial cell morphology

DNAI1 PTPRZ1 FUCA1

3.38e-03272163MP:0000952
MousePhenoabnormal vena cava morphology

DNAH5 DNAI1

3.42e-0377162MP:0006062
MousePhenoabnormal heart right ventricle size

ADA DNAH5

3.51e-0378162MP:0010577
Domain-

MYO15A GAL3ST3 ADCY10 DNAH5 DDX51

1.50e-037462253.40.50.300
DomainP-loop_NTPase

MYO15A GAL3ST3 ADCY10 DNAH5 DDX51

2.63e-03848225IPR027417
DomainARM-like

IPO5 HUWE1 USP9Y

3.75e-03270223IPR011989
DomainARM-type_fold

IPO5 HUWE1 USP9Y

7.07e-03339223IPR016024
Pubmed

Primary ciliary dyskinesia: improving the diagnostic approach.

DNAH5 DNAI1

3.82e-07222219300264
Pubmed

Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary ciliary dyskinesia.

DNAH5 DNAI1

3.82e-07222217515466
Pubmed

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.

DNAH5 DNAI1

1.15e-06322226918822
Pubmed

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

DNAH5 DNAI1

1.15e-06322215750039
Pubmed

A targeted next-generation sequencing panel reveals novel mutations in Japanese patients with primary ciliary dyskinesia.

DNAH5 DNAI1

2.29e-06422228939216
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAI1

2.29e-06422218492703
Pubmed

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.

DNAH5 DNAI1

2.29e-06422218950741
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAH5 DNAI1

3.82e-06522222499950
Pubmed

The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.

DNAH5 DNAI1

3.82e-06522223525783
Pubmed

ZMYND10 functions in a chaperone relay during axonemal dynein assembly.

DNAH5 DNAI1

1.71e-051022229916806
Pubmed

Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11.

IPO5 HUWE1

2.09e-051122211809816
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

IPO5 NAA15 HUWE1

5.74e-0511922335776542
Pubmed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

DNAH5 DNAI1

1.14e-042522227340223
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

IPO5 PPCS SELENOI NAA15 HUWE1

1.87e-0487822537223481
Pubmed

Primary Ciliary Dyskinesia

DNAH5 DNAI1

1.87e-043222220301301
Pubmed

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.

IPO5 HUWE1

3.24e-044222232738194
Pubmed

Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.

UBR1 HUWE1

4.59e-045022217550899
GeneFamilyDyneins, axonemal

DNAH5 DNAI1

1.26e-0417182536
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO15A ADCY10 USP9Y

4.83e-0514522396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1 PTPRZ1

5.89e-051552235f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1 PTPRZ1

5.89e-051552230944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1 PTPRZ1

6.59e-05161223472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1 PTPRZ1

6.96e-05164223e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBR1 SELENOI HUWE1

1.09e-041912239454f642c3621370fa23640b631301346b300950
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH5 DNAI1 PTPRZ1

1.13e-04193223ea345d34440b25f65358a53dc72831998d1c3620
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.22e-04198223e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.22e-04198223e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.22e-04198223e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.22e-04198223ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.23e-041992236aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.23e-0419922360919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.25e-04200223da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-GGH-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRZ1 OR1S2 SLC10A4

1.25e-0420022348303e499251d6754cfa991dc2d96c5563b2123c
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.25e-04200223a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.25e-0420022396701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.25e-04200223cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-GGH|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPRZ1 OR1S2 SLC10A4

1.25e-042002234802dd6cae84b41746227a5d1aa1c9b858495e36
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAH5 DNAI1 PTPRZ1

1.25e-0420022372c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Htr1b-Inhibitory_Gad1Gad2_Htr3a.Htr1b_(Interneuron,__(candidate_CGE-derived_11))|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC10A4 USP9Y

4.66e-04652222cf855eed46ba9e1354ac3b5c18d4adcc3e0e7a5
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Htr1b-Inhibitory_Gad1Gad2_Htr3a.Htr1b_(Interneuron,__(candidate_CGE-derived_11))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC10A4 USP9Y

4.66e-0465222f44998b87dc7015b79ca8f8d60f9d7845755b8bb
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Htr1b|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC10A4 USP9Y

4.66e-04652229a4c853e2723a23b537d2966c6583909d0d0aeb2
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-A|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ADCY10 USP9Y

1.37e-03112222d21cfcb04a27cc9fb74e0c2afa8a8cdfb886ae21
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADCY10 FGFR1

1.73e-031262229b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADCY10 FGFR1

2.01e-031362221f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH5 DNAI1

2.04e-03137222b831d917f5073ccff158662adb281d34f023126a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH5 DNAI1

2.04e-03137222cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

DNAI1 FGFR1

2.04e-03137222b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH5 DNAI1

2.04e-031372225d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 PTPRZ1

2.07e-03138222615822e542f12aa83df1561e262b8d72bdefc60e
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO15A DNAI1

2.19e-03142222a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO15A DNAI1

2.19e-03142222d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRZ1 USP9Y

2.22e-031432227a7a9829ba63468c9745904d9e993590051207ab
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRZ1 SLC10A4

2.28e-0314522278f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

ADCY10 SLC10A4

2.38e-03148222afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.38e-03148222d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

ADCY10 SLC10A4

2.38e-031482225f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.38e-03148222c8e93b87212f55774223caa385859c566fa1981f
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

PTPRZ1 PLPP7

2.41e-03149222dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

IPO5 DNAH5

2.44e-03150222b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.47e-0315122281cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.47e-031512229cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH5 DNAI1

2.47e-031512228216462e723fec2797387929dde095370947e10a
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH5 PTPRZ1

2.51e-031522221b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.57e-031542224e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.57e-031542227556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.57e-0315422258072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 DNAI1

2.57e-031542229ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRZ1 SLC10A4

2.60e-031552223b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

DDX51 USP9Y

2.64e-0315622225b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCellControl-Epithelial_airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 PTPRZ1

2.70e-0315822235aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

GAL3ST3 FGFR1

2.74e-031592224f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPO5 ADA

2.74e-03159222f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRZ1 SLC10A4

2.80e-031612223b5d7a3dab479c6959a428f3954dedd989900276
ToppCell367C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ADCY10 ADA

2.80e-03161222c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell367C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ADCY10 ADA

2.80e-031612229864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADCY10 USP9Y

2.84e-03162222bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH5 DNAI1

2.91e-03164222d9531848105d606adedde65426177cf851140e31
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 PTPRZ1

2.91e-03164222b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 PTPRZ1

2.91e-0316422256e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 PTPRZ1

2.91e-03164222c5b2001280a43da855017361a3f6071a0e492848
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH5 FGFR1

2.91e-031642221cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DNAH5 DNAI1

2.94e-031652220c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DNAH5 DNAI1

2.94e-0316522282530f96aaefe28a13bad0474bbad043f127a86c
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLPP7 FGFR1

2.98e-031662223b750d4023a0a09d86113aae5a97d84391f7b482
ToppCellLPS-antiTNF-Epithelial_airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 PTPRZ1

2.98e-03166222eb942ed68677e55c46cb039046f45686d4062d7c
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DNAH5 DNAI1

3.01e-0316722226cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPP7 DDX51

3.01e-03167222d15168f46c1599d9fc68a05a7b822c4b439f2987
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

DNAH5 DNAI1

3.01e-03167222442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPP7 DDX51

3.01e-031672222812353ff66e76f10bd327ceb0e6b009502a5258
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DDX51 USP9Y

3.01e-03167222dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRZ1 SLC10A4

3.05e-03168222f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 PLPP7

3.05e-03168222794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 PLPP7

3.05e-031682226fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 PLPP7

3.05e-031682221e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

DNAH5 DNAI1

3.08e-03169222425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 PTPRZ1

3.08e-0316922286041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAL3ST3 PTPRZ1

3.08e-031692222456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH5 PTPRZ1

3.08e-031692228c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

ADA SELENOI

3.08e-031692226abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADA PLPP7

3.08e-03169222f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related-FDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAL3ST3 DNAH5

3.08e-0316922249a54fb2ea9db5c45e107f304838c536908308bb
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH5 DNAI1

3.08e-0316922214aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Lung-EPCAM-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO15A DNAH5

3.12e-0317022282ccba6ec53f6ca0d19949a1277434c565af2983
ToppCelldroplet-Fat-Bat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 PLPP7

3.12e-03170222c4ecdfc2b4710da0a5fbb20e9df02536023badb1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRZ1 SLC10A4

3.12e-0317022236dbbdb13f69307afd2122ff051b2980850c1f00
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO15A DNAH5

3.12e-03170222ab19ea729ed8c8361c870e79893d1a95a1e487fa
ToppCelldroplet-Fat-Bat-18m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 PLPP7

3.12e-03170222c720d81bc29a8fd1f1249c6af408471d561f1d5d
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15A GAL3ST3

3.16e-03171222e780e63510ca47036bc36ca40ecff4098596ee9e
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GAL3ST3 NAA15

3.16e-03171222effcc4b6d26eafc2ca6fa08b6fee2689eff48f0f
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DNAH5 DNAI1

3.19e-0317222208ad76412c9cc3504141797b44b88478ced87476
ToppCellASK454-Epithelial-Transformed_epithelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

MYO15A DDX51

3.19e-031722223986f0f098ef5e096c8d9ee3d335b8404083701f
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH5 DNAI1

3.23e-03173222c3762655caa79ac4879876f470d32578a3c93b01
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH5 PTPRZ1

3.23e-03173222464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GAL3ST3 FGFR1

3.23e-03173222b23b408acc29a667cce104429afef1a6cf2720a5
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPO5 PPCS

3.23e-0317322228c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH5 PTPRZ1

3.26e-03174222f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNAH5 DNAI1

3.26e-0317422200cf27bc23af1472a507be31fba6245a8fdd901b
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNAH5 DNAI1

3.26e-03174222b8d1c556290d188f56aeefc17f03119686945fe7
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAI1

3.18e-064222DOID:0050144 (is_implicated_in)
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 DNAI1

4.80e-0514222DOID:0050144 (implicated_via_orthology)
Diseaseotitis media (implicated_via_orthology)

DNAH5 FGFR1

1.21e-0422222DOID:10754 (implicated_via_orthology)
DiseaseBronchiectasis

DNAH5 DNAI1

1.21e-0422222C0006267
DiseasePrimary ciliary dyskinesia

DNAH5 DNAI1

3.29e-0436222cv:C0008780
Diseasevisceral heterotaxy (implicated_via_orthology)

DNAH5 DNAI1

3.48e-0437222DOID:0050545 (implicated_via_orthology)
DiseasePrimary Ciliary Dyskinesia

DNAH5 DNAI1

5.62e-0447222C4551720

Protein segments in the cluster

PeptideGeneStartEntry
LTLPDFLAKFDYYMP

ADA

56

P00813
LLYSLKNPSFPEYMF

DNAI1

366

Q9UI46
YGHFSPERPFMDYFD

ADCY10

26

Q96PN6
GYAFHPLMAALPAYF

OPN1LW

296

P04000
YMFPLLYALFQSAEA

SLC10A4

361

Q96EP9
ALPPYTMLEFAQKYF

MYO15A

3006

Q9UKN7
RFMRDNYPPGFSYAD

FUCA1

91

P04066
TDLEMPHYSTFAYFP

PTPRZ1

706

P23471
SPASFKYAEYFLRPM

IPO5

896

O00410
GFTSPMLFDERKYPY

HUWE1

1136

Q7Z6Z7
LFPYALAFMPPGYEE

NAA15

831

Q9BXJ9
PMYLFLAYLSFADIS

OR1S2

71

Q8NGQ3
PSAMFYLAAAVSDFY

PPCS

171

Q9HAB8
LREPAAMFESLFSYY

GAL3ST3

151

Q96A11
MALFYVARYPGPDAA

DDX51

1

Q8N8A6
YLDLSMPLDQYSPSF

FGFR1

766

P11362
LLMAYFDPDFYASAP

SELENOI

66

Q9C0D9
FLSPYFEMPDYNIET

DNAH5

3381

Q8TE73
AVYSFCLMNYFPLAP

FASTKD2

501

Q9NYY8
LDPLFMDPDLAYGTY

UBR1

1141

Q8IWV7
DYFEFPRELDMGPYT

USP9Y

1816

O00507
PSLLDYLTMDIYAFP

PLPP7

176

Q8NBV4