Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	ALG14 ALG13	3.52e-05	2	119	2	GO:0004577
GeneOntologyMolecularFunction	3'-tRNA processing endoribonuclease activity	ELAC2 ELAC1	3.52e-05	2	119	2	GO:0042781
GeneOntologyMolecularFunction	phosphopyruvate hydratase activity	ENO4 ENO1	2.10e-04	4	119	2	GO:0004634
GeneOntologyMolecularFunction	heat shock protein binding	APAF1 NR3C1 HNRNPK KDR ENO1 HSPA7	4.38e-04	163	119	6	GO:0031072
GeneOntologyMolecularFunction	ferroxidase activity	CP HEPHL1	5.20e-04	6	119	2	GO:0004322
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions, oxygen as acceptor	CP HEPHL1	5.20e-04	6	119	2	GO:0016724
GeneOntologyBiologicalProcess	dolichol-linked oligosaccharide biosynthetic process	MPDU1 ALG14 ALG3 ALG13	7.11e-06	22	119	4	GO:0006488
GeneOntologyBiologicalProcess	dolichol metabolic process	MPDU1 ALG14 ALG3 ALG13	1.02e-05	24	119	4	GO:0019348
GeneOntologyBiologicalProcess	polyprenol metabolic process	MPDU1 ALG14 ALG3 ALG13	2.24e-05	29	119	4	GO:0016093
GeneOntologyBiologicalProcess	positive regulation of cell growth	CPNE9 DDX49 SYT17 RICTOR NR3C1 HNRNPK ACSL4 TRIM32	3.33e-05	213	119	8	GO:0030307
GeneOntologyBiologicalProcess	regulation of cell growth	DIP2B CPNE9 DDX49 SYT17 RICTOR NR3C1 HNRNPK ACSL4 IFRD1 TRIM32 BST2 ENO1	4.69e-05	519	119	12	GO:0001558
Domain	Cu-oxidase_3	CP F5 HEPHL1	2.25e-06	5	115	3	IPR011707
Domain	MULTICOPPER_OXIDASE1	CP F5 HEPHL1	2.25e-06	5	115	3	PS00079
Domain	Cu_oxidase_CS	CP F5 HEPHL1	2.25e-06	5	115	3	IPR033138
Domain	Cu-oxidase_3	CP F5 HEPHL1	2.25e-06	5	115	3	PF07732
Domain	Cu_oxidase_Cu_BS	CP F5 HEPHL1	4.49e-06	6	115	3	IPR002355
Domain	-	SCYL1 RICTOR IFRD1 RIC8B INSC TTI1 PRKDC KPNA3	6.98e-05	222	115	8	1.25.10.10
Domain	-	CP F5 HEPHL1	7.88e-05	14	115	3	2.60.40.420
Domain	MULTICOPPER_OXIDASE2	CP HEPHL1	1.12e-04	3	115	2	PS00080
Domain	BRCT	TOPBP1 PARP4 DNTT	2.05e-04	19	115	3	PF00533
Domain	Cu-oxidase_2	CP HEPHL1	2.24e-04	4	115	2	IPR011706
Domain	Lactamase_B_2	ELAC2 ELAC1	2.24e-04	4	115	2	PF12706
Domain	Cu-oxidase_2	CP HEPHL1	2.24e-04	4	115	2	PF07731
Domain	ARM-type_fold	SCYL1 RICTOR ARFGEF3 IFRD1 RIC8B INSC TTI1 PRKDC KPNA3	2.50e-04	339	115	9	IPR016024
Domain	ARM-like	SCYL1 RICTOR IFRD1 RIC8B INSC TTI1 PRKDC KPNA3	2.68e-04	270	115	8	IPR011989
Domain	Cupredoxin	CP F5 HEPHL1	3.22e-04	22	115	3	IPR008972
Domain	BRCT	TOPBP1 PARP4 DNTT	3.22e-04	22	115	3	SM00292
Domain	-	TOPBP1 PARP4 DNTT	3.68e-04	23	115	3	3.40.50.10190
Domain	BRCT	TOPBP1 PARP4 DNTT	5.33e-04	26	115	3	PS50172
Domain	CARD	APAF1 CARD18 CARD14	6.66e-04	28	115	3	PF00619
Domain	BRCT_dom	TOPBP1 PARP4 DNTT	6.66e-04	28	115	3	IPR001357
Domain	Tudor	TDRD5 PHF19 ALG13	8.18e-04	30	115	3	IPR002999
Domain	AMP-binding	DIP2B ACSL4 SLC27A2	8.18e-04	30	115	3	PF00501
Domain	AMP-dep_Synth/Lig	DIP2B ACSL4 SLC27A2	8.18e-04	30	115	3	IPR000873
Domain	CARD	APAF1 CARD18 CARD14	9.01e-04	31	115	3	IPR001315
Domain	CARD	APAF1 CARD18 CARD14	1.08e-03	33	115	3	PS50209
Domain	Copine	CPNE8 CPNE9	1.32e-03	9	115	2	PF07002
Domain	Copine	CPNE8 CPNE9	1.32e-03	9	115	2	IPR010734
Domain	-	NLRP11 APAF1 CARD18 CARD14	2.61e-03	93	115	4	1.10.533.10
Domain	Lactamase_B	ELAC2 ELAC1	2.80e-03	13	115	2	PF00753
Domain	DEATH-like_dom	NLRP11 APAF1 CARD18 CARD14	3.28e-03	99	115	4	IPR011029
Domain	Lactamase_B	ELAC2 ELAC1	3.74e-03	15	115	2	SM00849
Domain	Poly(ADP-ribose)pol_cat_dom	PARP4 PARP15	4.81e-03	17	115	2	IPR012317
Domain	PARP_CATALYTIC	PARP4 PARP15	4.81e-03	17	115	2	PS51059
Domain	PARP	PARP4 PARP15	4.81e-03	17	115	2	PF00644
Domain	-	PARP4 PARP15	4.81e-03	17	115	2	3.90.228.10
Domain	ZF_ZZ_2	HERC2 NBR1	5.39e-03	18	115	2	PS50135
Domain	ZF_ZZ_1	HERC2 NBR1	5.39e-03	18	115	2	PS01357
Domain	ZZ	HERC2 NBR1	5.39e-03	18	115	2	PF00569
Domain	Znf_ZZ	HERC2 NBR1	6.00e-03	19	115	2	IPR000433
Domain	ZnF_ZZ	HERC2 NBR1	6.00e-03	19	115	2	SM00291
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_N_GLYCOSYLATION_OF_PROTEINS	MPDU1 ALG14 ALG3 ALG13	6.66e-06	20	89	4	M27274
Pathway	WP_GLYCOSYLATION_AND_RELATED_CONGENITAL_DEFECTS	MPDU1 ALG14 ALG3 ALG13	1.70e-05	25	89	4	M39813
Pathway	WP_NGLYCAN_BIOSYNTHESIS	MPDU1 ALG14 ALG3 GMPPA ALG13	2.90e-05	57	89	5	M48051
Pathway	REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN	MPDU1 ALG14 ALG3 GMPPA ALG13	1.24e-04	77	89	5	MM15118
Pathway	REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN	MPDU1 ALG14 ALG3 GMPPA ALG13	1.40e-04	79	89	5	M897
Pubmed	Defining the membrane proteome of NK cells.	DIP2B LONP2 MPDU1 SCYL1 RNF213 F5 HNRNPK ACSL4 PARP4 INTS5 ATP11B BST2 FANCI TNK2 PRKDC HERC2 ENO1 NBR1	1.11e-07	1168	120	18	19946888
Pubmed	Congenital Disorders of N-Linked Glycosylation and Multiple Pathway Overview	MPDU1 PGM1 ALG3 GMPPA ALG13	4.38e-07	44	120	5	20301507
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DDX49 SPTLC2 ACO2 NEK7 RICTOR UBXN1 DDX27 ELAC2 HNRNPK ACSL4 TRIM32 NSA2 FANCI ASPH PRKDC HERC2 ENO1 KPNA3	9.43e-07	1353	120	18	29467282
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TREX1 DYNC2H1 SPTLC2 ACO2 RNF213 PGM1 SETD2 INTS5 FANCI EIF2S3 ALG14 TTI1 PRKDC NBR1 ALG13	3.99e-06	1061	120	15	33845483
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	RICTOR TTI1 PRKDC	6.48e-06	11	120	3	20427287
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	DDX49 HNRNPK ACSL4 EIF2S3 RNF146 ASPH PRKDC GMPPA ENO1 HSPA7	7.63e-06	486	120	10	30940648
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	RNF213 DDX27 ASPH PRKDC ALDH1A1 ATP1B1	1.12e-05	144	120	6	35681168
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	ZFYVE16 SPTLC2 ACOT13 MPDU1 NR3C1 HNRNPK ACSL4 FANCI PRKDC GMPPA ENO1 HSPA7 KPNA3	1.13e-05	878	120	13	37223481
Pubmed	K+ channel alterations in the progression of experimental autoimmune encephalomyelitis.	KCNA4 KCNB1	1.18e-05	2	120	2	22560931
Pubmed	Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor.	NR3C1 PRKDC	1.18e-05	2	120	2	9038175
Pubmed	Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis.	ACO2 OGG1	1.18e-05	2	120	2	19524665
Pubmed	Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.	AGER PRKDC	1.18e-05	2	120	2	21298413
Pubmed	Identification of zyklopen, a new member of the vertebrate multicopper ferroxidase family, and characterization in rodents and human cells.	CP HEPHL1	1.18e-05	2	120	2	20685892
Pubmed	The Placental Ferroxidase Zyklopen Is Not Essential for Iron Transport to the Fetus in Mice.	CP HEPHL1	1.18e-05	2	120	2	34114013
Pubmed	A candidate prostate cancer susceptibility gene at chromosome 17p.	ELAC2 ELAC1	1.18e-05	2	120	2	11175785
Pubmed	An in vitro assay for enzymatic studies on human ALG13/14 heterodimeric UDP-N-acetylglucosamine transferase.	ALG14 ALG13	1.18e-05	2	120	2	36200043
Pubmed	Membrane topology of the Alg14 endoplasmic reticulum UDP-GlcNAc transferase subunit.	ALG14 ALG13	1.18e-05	2	120	2	17686769
Pubmed	Receptors for advanced glycation end products (RAGE) is associated with microvessel density and is a prognostic biomarker for clear cell renal cell carcinoma.	AGER KDR	1.18e-05	2	120	2	26211596
Pubmed	Methylglyoxal induced advanced glycation end products (AGE)/receptor for AGE (RAGE)-mediated angiogenic impairment in bone marrow-derived endothelial progenitor cells.	AGER KDR	1.18e-05	2	120	2	29473788
Pubmed	Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation.	ALG14 ALG13	1.18e-05	2	120	2	16100110
Pubmed	Mitochondria-targeted Ogg1 and aconitase-2 prevent oxidant-induced mitochondrial DNA damage in alveolar epithelial cells.	ACO2 OGG1	1.18e-05	2	120	2	24429287
Pubmed	Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.	KCNA4 KCNB1	1.18e-05	2	120	2	20643768
Pubmed	Localization of human RNase Z isoforms: dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation.	ELAC2 ELAC1	1.18e-05	2	120	2	21559454
Pubmed	A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease.	ELAC2 ELAC1	1.18e-05	2	120	2	12711671
Pubmed	B-1a cell diversity: nontemplated addition in B-1a cell Ig is determined by progenitor population and developmental location.	PRKDC DNTT	1.18e-05	2	120	2	24477911
Pubmed	Sexually dimorphic expression of the X-linked gene Eif2s3x mRNA but not protein in mouse brain.	EIF2S3B EIF2S3	1.18e-05	2	120	2	16325480
Pubmed	Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells.	PRKDC ARHGEF6	3.53e-05	3	120	2	19918261
Pubmed	The Chinese hamster gene map. Assignment of four genes (DTS, PGM2, 6PGD, EnoI) to chromosome 2.	PGM1 ENO1	3.53e-05	3	120	2	6445830
Pubmed	Identification of histological markers for malignant glioma by genome-wide expression analysis: dynein, alpha-PIX and sorcin.	DYNC2H1 ARHGEF6	3.53e-05	3	120	2	16320026
Pubmed	Disruption of a spermatogenic cell-specific mouse enolase 4 (eno4) gene causes sperm structural defects and male infertility.	ENO4 ENO1	3.53e-05	3	120	2	23446454
Pubmed	Membrane Anchoring by a C-terminal Tryptophan Enables HIV-1 Vpu to Displace Bone Marrow Stromal Antigen 2 (BST2) from Sites of Viral Assembly.	CD55 BST2	3.53e-05	3	120	2	25759385
Pubmed	[Ceruloplasmin, hephaestin and zyklopen: the three multicopper oxidases important for human iron metabolism].	CP HEPHL1	3.53e-05	3	120	2	24988611
Pubmed	Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy.	NR3C1 AGER	3.53e-05	3	120	2	17446934
Pubmed	Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs.	ELAC2 ELAC1	3.53e-05	3	120	2	21593607
Pubmed	Enhancing Acsl4 in absence of mTORC2/Rictor drove β-cell dedifferentiation via inhibiting FoxO1 and promoting ROS production.	RICTOR ACSL4	3.53e-05	3	120	2	34455055
Pubmed	FGF signalling controls expression of vomeronasal receptors during embryogenesis.	ALDH1A1 OC90	3.53e-05	3	120	2	16326081
Pubmed	Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population?	OGG1 PRKDC	3.53e-05	3	120	2	19815090
Pubmed	Biochemical characterization of copine: a ubiquitous Ca2+-dependent, phospholipid-binding protein.	CPNE8 CPNE9	3.53e-05	3	120	2	11123945
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CPNE8 SPTLC2 RNF213 DDX27 ARFGEF3 NSA2 BST2 FANCI EIF2S3 SYNE2 ASPH PRKDC ATP1B1 ENO1 SLC27A2 KPNA3	3.69e-05	1440	120	16	30833792
Pubmed	Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.	RICTOR TTI1 PRKDC	3.73e-05	19	120	3	20801936
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	ACO2 DDX27 HNRNPK ACSL4 EIF2S3 ASPH PRKDC HEPHL1 ENO1 TNS1 SLC27A2	3.73e-05	711	120	11	33022573
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	SYT17 ACO2 SCYL1 HNRNPK SETD2 TRIM32 ENO1 NBR1 ALG13 KPNA3	5.14e-05	608	120	10	16713569
Pubmed	Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants.	SYT17 CP F5 IFRD1 HSPA7	5.54e-05	117	120	5	12107410
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	DDX49 LONP2 TOPBP1 CD55 RICTOR DDX27 SETD2 IFRD1 INTS5 TRIM32 NSA2 EIF2S3 ASPH HERC2 ATP1B1 KPNA3	5.84e-05	1497	120	16	31527615
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	MPDU1 CD55 RICTOR ACSL4 EIF2S3 ASPH ATP1B1 SLC27A2	6.80e-05	392	120	8	33144569
Pubmed	Homologous genes for enolase, phosphogluconate dehydrogenase, phosphoglucomutase, and adenylate kinase are syntenic on mouse chromosome 4 and human chromosome 1p.	PGM1 ENO1	7.05e-05	4	120	2	209463
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	DYNC2H1 RNF213	7.05e-05	4	120	2	26147384
Pubmed	Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB.	EIF2S3B EIF2S3	7.05e-05	4	120	2	31836389
Pubmed	RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.	RICTOR ACSL4	7.05e-05	4	120	2	38040804
Pubmed	An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.	CXCR6 PRKDC	7.05e-05	4	120	2	30220458
Pubmed	mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes.	RICTOR PRKDC	7.05e-05	4	120	2	16221682
Pubmed	Neuronal ER-plasma membrane junctions organized by Kv2-VAP pairing recruit Nir proteins and affect phosphoinositide homeostasis.	PITPNM2 KCNB1	7.05e-05	4	120	2	31594866
Pubmed	Focal and segmental glomerulosclerosis induced in mice lacking decay-accelerating factor in T cells.	CD55 PRKDC	7.05e-05	4	120	2	19349693
Pubmed	The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins.	BRAP SYNE2	7.05e-05	4	120	2	23707952
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	CPNE8 CPNE9 CILP CD55 CP PGM1 HNRNPK SLC12A3 ALDH1A1 ATP1B1 GMPPA ENO1 HSPA7	8.63e-05	1070	120	13	23533145
Pubmed	PIDD orchestrates translesion DNA synthesis in response to UV irradiation.	TRIM32 FANCI PRKDC	8.72e-05	25	120	3	21415862
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DIP2B DMXL2 LONP2 RICTOR NR3C1 FAM111B PARP4 TRIM32 EIF2S3 ASPH	8.92e-05	650	120	10	38777146
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	DYNC2H1 ACO2 CP RICTOR HNRNPK EIF2S3 PRKDC ALDH1A1 ATP1B1 ENO1 ALG13	1.15e-04	807	120	11	30575818
Pubmed	Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.	SCYL1 PGM1 KCNB1 ATP1B1	1.16e-04	72	120	4	19723774
Pubmed	The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells.	MMS22L PRKDC	1.17e-04	5	120	2	29478807
Pubmed	Decay-accelerating factor induction on vascular endothelium by vascular endothelial growth factor (VEGF) is mediated via a VEGF receptor-2 (VEGF-R2)- and protein kinase C-alpha/epsilon (PKCalpha/epsilon)-dependent cytoprotective signaling pathway and is inhibited by cyclosporin A.	CD55 KDR	1.17e-04	5	120	2	15284224
Pubmed	Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes.	HNRNPK CXCL11	1.17e-04	5	120	2	25713416
Pubmed	Distinct roles of heterogeneous nuclear ribonuclear protein K and microRNA-16 in cyclooxygenase-2 RNA stability induced by S100b, a ligand of the receptor for advanced glycation end products.	HNRNPK AGER	1.17e-04	5	120	2	18854308
Pubmed	Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.	AGER TNS1	1.17e-04	5	120	2	21965014
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP11B ATP2C2 ATP1B1	1.37e-04	29	120	3	15071553
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	RNF213 PRKDC HERC2 ENO1	1.43e-04	76	120	4	27542412
Pubmed	Network organization of the human autophagy system.	FNBP1 DIP2B NEK7 PGM1 FANCI ASPH PRKDC NBR1	1.44e-04	437	120	8	20562859
Pubmed	Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.	TRIM32 FANCI PRKDC	1.52e-04	30	120	3	34017080
Pubmed	UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.	RICTOR PRKDC ENO1	1.52e-04	30	120	3	32867711
Pubmed	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.	DIP2B CPNE8 CD55 HNRNPK ACSL4 BST2 EIF2S3 ATP1B1 ENO1	1.57e-04	565	120	9	20458337
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	TDRD5 CPNE8 CPNE9 RNF213 UBXN1 DDX27 HNRNPK TRIM32 PRKDC ENO1 HSPA7	1.70e-04	844	120	11	25963833
Pubmed	The non-receptor tyrosine kinase Ack1 regulates the fate of activated EGFR by inducing trafficking to the p62/NBR1 pre-autophagosome.	TNK2 NBR1	1.75e-04	6	120	2	24413169
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DIP2B ACO2 SCYL1 RNF213 DDX27 ELAC2 HNRNPK FAM111B ARFGEF3 ACSL4 NSA2 SYNE2 HERC2 NBR1 ALG13	2.03e-04	1496	120	15	32877691
Pubmed	Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development.	EIF2S3B EIF2S3	2.45e-04	7	120	2	15669143
Pubmed	Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1.	F5 ATP1B1	2.45e-04	7	120	2	1694218
Pubmed	Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation.	KCNA4 KCNB1	2.45e-04	7	120	2	9852577
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	TOPBP1 HNRNPK FANCI EIF2S3 PRKDC ENO1 KPNA3	2.50e-04	357	120	7	37059091
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	PITPNM2 DIP2B ACOT13 F5 HNRNPK HERC2 ENO1 KPNA3	2.53e-04	475	120	8	31040226
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DYNC2H1 SPTLC2 RICTOR PARP4 FANCI TTI1 HERC2 GMPPA KPNA3	2.63e-04	606	120	9	36538041
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	RNF213 UBXN1 BRAP TRIM32 TNK2 HERC2 NBR1 SLC27A2	2.75e-04	481	120	8	28190767
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ZFYVE16 RNF213 RICTOR DDX27 ACSL4 FANCI SYNE2 TTI1 HERC2 TNS1 NBR1 KPNA3	2.83e-04	1049	120	12	27880917
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	SPTLC2 SMOC1 DDX27 TRIM32 FANCI TTI1 HERC2 ATP1B1 SLC27A2 KPNA3	2.95e-04	754	120	10	33060197
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	CPNE8 EIF2S3B HNRNPK EIF2S3 AK5 ALDH1A1 ATP1B1 ENO1 CARD14	3.14e-04	621	120	9	22794259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DMXL2 DYNC2H1 SPTLC2 RNF213 RICTOR NPHP4 PARP4 SETD2	3.24e-04	493	120	8	15368895
Pubmed	Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells.	CD55 PRKDC	3.26e-04	8	120	2	23690475
Pubmed	Bridging expressed sequence alignments through targeted cDNA sequencing.	DIP2B CPNE9	3.26e-04	8	120	2	15028280
Pubmed	A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.	SLC12A3 KDR	3.26e-04	8	120	2	38906145
Pubmed	A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.	TTI1 PRKDC	3.26e-04	8	120	2	20810650
Pubmed	Glucocorticoid signalling affects pancreatic development through both direct and indirect effects.	NR3C1 PRKDC	3.26e-04	8	120	2	17001468
Pubmed	Temporally compartmentalized expression of ephrin-B2 during renal glomerular development.	SLC12A3 KDR	3.26e-04	8	120	2	11729236
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	DIP2B DMXL2 APAF1 SCYL1 HNRNPK EIF2S3 SYNE2 TTI1	3.46e-04	498	120	8	36634849
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DIP2B DMXL2 DDX49 ACO2 MPDU1 HNRNPK SETD2 INTS5 TRIM32 PRKDC ARHGEF6 KPNA3	3.74e-04	1082	120	12	38697112
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	FNBP1 DYNC2H1 MPDU1 NR3C1 ACSL4 PARP4 NSA2 ASXL3 SYNE2	3.82e-04	638	120	9	31182584
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	EIF2S3B HNRNPK INTS5 EIF2S3 SYNE2 ENO1	4.14e-04	277	120	6	30745168
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	DDX49 ZFYVE16 TOPBP1 CP F5 ELAC2 FAM111B CCDC66 ARHGEF6	4.14e-04	645	120	9	25281560
Pubmed	Genome-wide association study identifies five loci associated with lung function.	AGER TNS1	4.18e-04	9	120	2	20010834
Pubmed	The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.	CPNE8 CPNE9	4.18e-04	9	120	2	9430674
Pubmed	Wnt pathway anomalies in developing amygdalae of Turner syndrome-like mice.	EIF2S3B EIF2S3	4.18e-04	9	120	2	17873295
Pubmed	Delineating HIV-associated neurocognitive disorders using transgenic models: the neuropathogenic actions of Vpr.	CASP6 BST2	4.18e-04	9	120	2	21918813
Pubmed	SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.	RICTOR TTI1	4.18e-04	9	120	2	23263282
GeneFamily	UDP-N-acetylglucosaminyltransferase subunits\|OTU domain containing\|Tudor domain containing	ALG14 ALG13	2.03e-05	2	82	2	449
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	APAF1 CARD18 CARD14	3.34e-04	30	82	3	959
GeneFamily	Tudor domain containing	TDRD5 PHF19 ALG13	6.25e-04	37	82	3	780
GeneFamily	Copines	CPNE8 CPNE9	7.17e-04	9	82	2	829
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP4 PARP15	2.64e-03	17	82	2	684
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	HERC2 NBR1	2.97e-03	18	82	2	91
Coexpression	CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3	TREX1 DMXL2 SYT17 CD55 CP F5 NSUN7 PGM1 ARFGEF3 SLC16A14 ATP2C2 ASPH ATP1B1 SLC27A2	6.16e-06	726	120	14	M4210
Coexpression	PUJANA_ATM_PCC_NETWORK	SPTLC2 TOPBP1 NEK7 NR3C1 NPHP4 OGG1 DDX27 ELAC2 HNRNPK ATP11B KCNB1 TRIM32 NSA2 FANCI EIF2S3 PRKDC NBR1 ARHGEF6 MX2	1.88e-05	1394	120	19	M9585
Coexpression	XIE_ST_HSC_S1PR3_OE_UP	RNF213 CSMD3 BST2 AK5 KDR CXCL11 MX2	2.72e-05	189	120	7	M41755
Coexpression	GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN	TDRD5 TREX1 RNF213 ELAC2 PARP4 SLC12A3 SLC16A14	3.77e-05	199	120	7	M8481
Coexpression	GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_UP	FNBP1 MMS22L ACOT13 TOPBP1 SCYL1 ELAC2 BRAP	3.90e-05	200	120	7	M7749
ToppCell	CV-Mild\|CV / Virus stimulation, Condition and Cluster	TREX1 GIMAP5 RNF213 CXCR6 BST2 EIF2S3 SYNE2 KLRC1	5.75e-08	194	120	8	0ce0376c12d8a2ca617f96dd1b7874393238d5a9
ToppCell	systemic_lupus_erythematosus-treated\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GIMAP5 RNF213 HNRNPK BST2 EIF2S3 SYNE2 ENO1 MX2	6.73e-08	198	120	8	8165ff735095c52994fb5057d89be93cc378b7da
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	DIP2B GIMAP5 CD55 SETD2 CCDC66 EIF2S3 AK5	1.01e-06	195	120	7	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	Bronchial_Brush-Epithelial\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DYNC2H1 CP ARFGEF3 SYNE2 ALDH1A1 ATP1B1 SLC27A2	1.09e-06	197	120	7	272c7f4e582ef57564450540242b0db766b78328
ToppCell	control-CD163+_Monocytes_(Sample_ID1_d7)\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DMXL2 SPTLC2 RNF213 BST2 ALDH1A1 CXCL11 MX2	1.16e-06	199	120	7	933201d32eda12a89660bdbae9114a95cc428a38
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_only / Treatment groups by lineage, cell group, cell type	MBD3L1 TDRD5 CP ARFGEF3 KDR HEPHL1 ATP1B1	1.16e-06	199	120	7	165ac94b2d56072ad43358b5127d77555221e2d8
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	GIMAP5 RNF213 RIC8B BST2 KDR MX2	5.35e-06	163	120	6	d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCell	(03)_Secretory-(0)_uninjured\|(03)_Secretory / shred by cell type and Timepoint	CP ARFGEF3 BST2 ALDH1A1 ATP1B1 SLC27A2	7.78e-06	174	120	6	ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	RICTOR SMOC1 CSMD3 DSCAML1 KCNB1 NBR1	8.58e-06	177	120	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	15-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	CD55 CP SLC7A8 ARFGEF3 KDR ALDH1A1	8.86e-06	178	120	6	f0557920b9b3e7c4f39938d1b524aa58711af4d2
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP ARFGEF3 ACSL4 SYNE2 ASPH ATP1B1	9.15e-06	179	120	6	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages\|bone_marrow / Manually curated celltypes from each tissue	CPNE9 NMNAT3 SLC7A8 ALDH1A1 ATP1B1 TNS1	9.44e-06	180	120	6	daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD55 CP ARFGEF3 ATP2C2 FAM181A ALDH1A1	9.75e-06	181	120	6	bab282cb0d9fc049f6fb094cf8b1fba104f4ea17
ToppCell	droplet-Kidney-nan-21m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACO2 SLC7A8 SLC12A3 ATP1B1 TNS1 SLC27A2	1.01e-05	182	120	6	942c18a27b22fb33a5200d5717cad972f3ef0576
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	RNF213 NR3C1 SETD2 SYNE2 CXCL11 MX2	1.04e-05	183	120	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	DMXL2 CPNE8 MMS22L RNF213 PRKDC SLC27A2	1.10e-05	185	120	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD55 CP SLC16A14 ASPH NMBR ATP1B1	1.17e-05	187	120	6	71d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PITPNM2 CP DSCAML1 ACSL4 ANKRD34B SYNE2	1.25e-05	189	120	6	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PITPNM2 CP DSCAML1 ACSL4 ANKRD34B SYNE2	1.25e-05	189	120	6	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SMOC1 CSMD3 DSCAML1 KCNA4 KCNB1 TNK2	1.28e-05	190	120	6	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	Control-Treg\|Control / Disease group and Cell class	PHF19 NEK7 F5 IFRD1 ATP1B1 ENO1	1.36e-05	192	120	6	3a9a8ac2aa278adde848608f9bb92a002dbb9bcc
ToppCell	CV-Healthy-1\|CV / Virus stimulation, Condition and Cluster	TREX1 GIMAP5 RNF213 NR3C1 BST2 MX2	1.36e-05	192	120	6	934d2e6a65121b24b91d386f7940fb9c1a7357ab
ToppCell	CV-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	TREX1 RNF213 BST2 ENO1 MX2 SLC27A2	1.36e-05	192	120	6	2a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CP NR3C1 SMOC1 F5 DSCAML1 SLC27A2	1.36e-05	192	120	6	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	control-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GIMAP5 RNF213 PARP4 ATP11B CXCR6 KLRC1	1.40e-05	193	120	6	89d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	DIP2B ZFYVE16 SPTLC2 ARFGEF3 ATP11B PRKDC	1.40e-05	193	120	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD55 CP ARFGEF3 FAM181A KDR ATP1B1	1.44e-05	194	120	6	855d6acfcf323868ba98b213f06186ad4793d4ed
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD55 CP ARFGEF3 FAM181A KDR ATP1B1	1.44e-05	194	120	6	dc531cf9089f2c956621d70d49a2b8219b4b45c1
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD55 CP ARFGEF3 FAM181A KDR ATP1B1	1.44e-05	194	120	6	29a7770bdbea6081a9ed64a997cd92a1cbf4af58
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD55 CP ARFGEF3 FAM181A KDR ATP1B1	1.44e-05	194	120	6	ca051088f880154ae2fd3f0ab3cef5a8dba8c371
ToppCell	COVID-19_Mild-PLT_5\|COVID-19_Mild / Disease Group and Platelet Clusters	GIMAP5 TOPBP1 RNF213 SYNE2 GMPPA MX2	1.49e-05	195	120	6	bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell	Epithelial_cells-Club_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	FNBP1 CP BST2 KDR ALDH1A1 MX2	1.49e-05	195	120	6	b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RICTOR CCDC66 CXCR6 SYNE2 PRKDC KLRC1	1.53e-05	196	120	6	4a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	CP ARFGEF3 ACSL4 SYNE2 ASPH ATP1B1	1.58e-05	197	120	6	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	Sepsis-URO-Lymphocyte-T/NK-MAIT\|URO / Disease, condition lineage and cell class	GIMAP5 CASP6 KLHL35 CSMD3 CXCR6 SYNE2	1.62e-05	198	120	6	75db638278d4be2b0f406cd8871058a8352c5a86
ToppCell	LPS_only-Epithelial_alveolar\|LPS_only / Treatment groups by lineage, cell group, cell type	CD55 CP ACSL4 AGER SYNE2 ATP1B1	1.62e-05	198	120	6	655df75b9692d815c7f6910275e1f684ac63bf62
ToppCell	CV-Mild-1\|CV / Virus stimulation, Condition and Cluster	TREX1 GIMAP5 RNF213 BST2 SYNE2 MX2	1.62e-05	198	120	6	4b078714c49e7befb7b113d72485e712236d35fa
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PHF19 TOPBP1 FAM111B FANCI SYNE2 SLC27A2	1.67e-05	199	120	6	305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCell	Biopsy_IPF-Epithelial-SCGB3A2+_SCGB1A1+\|Biopsy_IPF / Sample group, Lineage and Cell type	CP ARFGEF3 FAM181A KDR ALDH1A1 ATP1B1	1.67e-05	199	120	6	c6150f5fe2ce4466149a4d553acb907034a72efb
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CD55 CP ACSL4 AGER ASPH ATP1B1	1.67e-05	199	120	6	bb2e839197b9a44b632c1bb716e48d885a1c8713
ToppCell	PSB-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CP ARFGEF3 ATP2C2 ALDH1A1 ATP1B1 SLC27A2	1.67e-05	199	120	6	58dcb0eedafa8629585dc99e53147e2287f49689
ToppCell	ASK428-Epithelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	CD55 ARFGEF3 AGER ATP2C2 ASPH TNS1	1.67e-05	199	120	6	ba2aaaeb4d9b448a6b9660b152fcac1a0e3fcfe7
ToppCell	(04)_Interm._basal>secr.\|World / shred by cell type by condition	CD55 CP ARFGEF3 ASPH ALDH1A1 ATP1B1	1.67e-05	199	120	6	ed399244433f781fc291a9bff16825b8a3ca294f
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PHF19 TOPBP1 FAM111B FANCI SYNE2 SLC27A2	1.67e-05	199	120	6	fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	GIMAP5 PARP4 CXCR6 SYNE2 ARHGEF6 SLC27A2	1.67e-05	199	120	6	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	Bronchial_Biopsy-Epithelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	CP SYNE2 ATP2C2 ALDH1A1 ATP1B1 SLC27A2	1.67e-05	199	120	6	ef5d8917c8d011184830a0b8197afc6266707b37
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 RNF213 BST2 SYNE2 KDR PARP15	1.72e-05	200	120	6	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	Bronchus_Control_(B.)-Epithelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CP ARFGEF3 SYNE2 ATP2C2 ALDH1A1 ATP1B1	1.72e-05	200	120	6	f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Club\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CD55 CP ARFGEF3 FAM181A ALDH1A1 ATP1B1	1.72e-05	200	120	6	85f946dd3831acf3488c87efba96689cc2667c3a
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	DYNC2H1 CP ARFGEF3 C6orf118 ALDH1A1 ATP1B1	1.72e-05	200	120	6	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	PHF19 TOPBP1 FAM111B FANCI PRKDC SLC27A2	1.72e-05	200	120	6	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	CP F5 SLC7A8 ENO4 C6orf118 STOML3	1.72e-05	200	120	6	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Club-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD55 CP ARFGEF3 FAM181A ALDH1A1 ATP1B1	1.72e-05	200	120	6	8a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Club\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD55 CP ARFGEF3 FAM181A ALDH1A1 ATP1B1	1.72e-05	200	120	6	30d428510c68da96c7c8cfd472f449ebb9631132
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	PHF19 TOPBP1 FAM111B FANCI PRKDC SLC27A2	1.72e-05	200	120	6	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Fos_(Deep_layer_pyramidal_cells--layer_5_(IEG))\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TDRD5 MMS22L KLHL35 C6orf118	5.60e-05	77	120	4	4879a1a72b950dadb78bc0312be75f1a32b935d5
ToppCell	MS-CD4-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	RNF213 F5 BST2 SYNE2 MX2	5.74e-05	152	120	5	b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 CD55 AK5 ASXL3 KDR	6.30e-05	155	120	5	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD34B ATP2C2 ALDH1A1 ATP1B1 SLC27A2	7.32e-05	160	120	5	028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD34B ATP2C2 ALDH1A1 ATP1B1 SLC27A2	7.32e-05	160	120	5	1f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CILP UGT2A2 PLPPR5 ARFGEF3 SLC16A14	7.54e-05	161	120	5	7c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GIMAP5 CASP6 CP SYNE2 HERC2	7.54e-05	161	120	5	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPDU1 CSMD3 INSC HEPHL1 DNTT	8.96e-05	167	120	5	7f3224af9b30082b927a822b91f96e0c88151b4e
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPDU1 CSMD3 INSC HEPHL1 DNTT	8.96e-05	167	120	5	a21a2b301d0a3d7a41e605f7a3c37548962a331d
ToppCell	facs-Brain_Myeloid-Hippocampus-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPDU1 CSMD3 INSC HEPHL1 DNTT	8.96e-05	167	120	5	0e746483773bde6582874a33591ab2a578d724eb
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BST2 KDR ATP1B1 TNS1 DNTT	9.48e-05	169	120	5	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPDU1 CSMD3 INSC HEPHL1 DNTT	9.74e-05	170	120	5	b4f2c05db2c2591561fd42febc72eed3b5e8f9fb
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACSL4 FANCI ASXL3 AGER ATP1B1	9.74e-05	170	120	5	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CP ARFGEF3 FAM181A KDR ATP1B1	1.00e-04	171	120	5	fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CP ARFGEF3 FAM181A KDR ATP1B1	1.00e-04	171	120	5	d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CP ARFGEF3 FAM181A KDR ATP1B1	1.00e-04	171	120	5	d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CP ARFGEF3 FAM181A KDR ATP1B1	1.00e-04	171	120	5	4347e6f62c04ea43299893ad4b79719049009a56
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARFGEF3 BST2 SYNE2 ATP1B1 DNTT	1.03e-04	172	120	5	30916a902c151907745756d14327e24adc34afef
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EIF2S3B DDX27 BST2 FANCI HEPHL1	1.06e-04	173	120	5	176d7dc103b8161c4e2d7dc74f2dc77ea1f2d2ed
ToppCell	PSB-critical-LOC-Epithelial-Secretory_LYPD2\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CD55 CP ALDH1A1 CXCL11	1.08e-04	91	120	4	9c61b9f3e9e4f0c9cb242e313d642c2b75705c88
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 NSUN7 KDR CXCL11 SLC27A2	1.09e-04	174	120	5	fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 NSUN7 KDR CXCL11 SLC27A2	1.09e-04	174	120	5	1f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SLC7A8 C6orf118 ATP1B1 KLRC1 SLC27A2	1.09e-04	174	120	5	e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP5 NSUN7 KDR CXCL11 SLC27A2	1.09e-04	174	120	5	ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BST2 KDR ATP1B1 MX2 DNTT	1.12e-04	175	120	5	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 CP ALDH1A1 TNS1 DNTT	1.12e-04	175	120	5	c1a8a55af825d5913095f919fa860828df9c273e
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 CP ALDH1A1 TNS1 DNTT	1.12e-04	175	120	5	78b453e220218c84557f244ef7a760e4a1952761
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TREX1 BST2 ATP1B1 TNS1 DNTT	1.15e-04	176	120	5	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TREX1 BST2 ATP1B1 TNS1 DNTT	1.15e-04	176	120	5	d4075796c38b775fe721abb47426e662a0d415e3
ToppCell	(03)_Secretory\|World / shred by cell type and Timepoint	CD55 CP ATP2C2 ALDH1A1 ATP1B1	1.15e-04	176	120	5	cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TREX1 BST2 ATP1B1 TNS1 DNTT	1.15e-04	176	120	5	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SLC7A8 C6orf118 ASPH ATP1B1 SLC27A2	1.15e-04	176	120	5	bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	CP FAM111B ARFGEF3 SYNE2 ALDH1A1	1.21e-04	178	120	5	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BST2 ASPH ATP1B1 TNS1 DNTT	1.24e-04	179	120	5	d50d29f26d5a2cd8c4cd4e1244e1bb8de072d159
ToppCell	droplet-Kidney-nan-18m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACO2 SLC7A8 SLC12A3 ATP1B1 SLC27A2	1.27e-04	180	120	5	cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TREX1 BST2 ATP1B1 TNS1 DNTT	1.27e-04	180	120	5	64f01494a4052186773720e10b4e7c724ff94547
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD55 CP SMOC1 FANCI ASPH	1.31e-04	181	120	5	e0c46e2d52c97893e5894a51d2699e8a8a11eefc
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TREX1 BST2 ATP1B1 TNS1 DNTT	1.31e-04	181	120	5	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TREX1 BST2 ATP1B1 TNS1 DNTT	1.31e-04	181	120	5	e2481291c236105774c53883e6f20da11941df9b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 DSCAML1 NMNAT3 PARP4 AK5	1.31e-04	181	120	5	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	356C-Lymphocytic-ILC-ILC-1\|ILC / Donor, Lineage, Cell class and subclass (all cells)	FNBP1 HNRNPK ENO1	1.35e-04	37	120	3	5208860d6b87c6c6fbf6e6c262fb2efc712ec2d3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 DSCAML1 ARFGEF3 KCNA4 ASXL3	1.41e-04	184	120	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD55 CP ARFGEF3 ANKRD34B KDR	1.41e-04	184	120	5	fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 DSCAML1 ARFGEF3 KCNA4 ASXL3	1.41e-04	184	120	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 DSCAML1 ARFGEF3 KCNA4 ASXL3	1.41e-04	184	120	5	2b19a8c5f823e00812908b23e66bb4e563278aff
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	APAF1 CSMD3 OGG1 FAM111B SETD2 SYNE2 KDR ALDH1A1	1.52e-07	148	118	8	C0279702
Disease	Sarcomatoid Renal Cell Carcinoma	APAF1 CSMD3 OGG1 FAM111B SETD2 SYNE2 ALDH1A1	8.66e-07	128	118	7	C1266043
Disease	Chromophobe Renal Cell Carcinoma	APAF1 CSMD3 OGG1 FAM111B SETD2 SYNE2 ALDH1A1	8.66e-07	128	118	7	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	APAF1 CSMD3 OGG1 FAM111B SETD2 SYNE2 ALDH1A1	8.66e-07	128	118	7	C1266044
Disease	Papillary Renal Cell Carcinoma	APAF1 CSMD3 OGG1 FAM111B SETD2 SYNE2 ALDH1A1	8.66e-07	128	118	7	C1306837
Disease	Renal Cell Carcinoma	APAF1 CSMD3 OGG1 FAM111B SETD2 SYNE2 ALDH1A1	8.66e-07	128	118	7	C0007134
Disease	MEHMO syndrome (implicated_via_orthology)	EIF2S3B EIF2S3	1.59e-05	2	118	2	DOID:0060801 (implicated_via_orthology)
Disease	Congenital disorder of glycosylation	MPDU1 PGM1 ALG3 ALG13	1.61e-05	38	118	4	cv:C0282577
Disease	Male sterility	OGG1 NSUN7 ENO4 ENO1	4.13e-05	48	118	4	C0917731
Disease	Male infertility	OGG1 NSUN7 ENO4 ENO1	4.13e-05	48	118	4	C0021364
Disease	Subfertility, Male	OGG1 NSUN7 ENO4 ENO1	4.13e-05	48	118	4	C0848676
Disease	brain ischemia (biomarker_via_orthology)	APAF1 CASP6 CP NR3C1 AGER	5.74e-05	102	118	5	DOID:2316 (biomarker_via_orthology)
Disease	hepatitis (biomarker_via_orthology)	OGG1 F5	9.46e-05	4	118	2	DOID:2237 (biomarker_via_orthology)
Disease	Brain Diseases	TREX1 CP OGG1	1.34e-04	25	118	3	C0006111
Disease	Encephalopathies	TREX1 CP OGG1	1.70e-04	27	118	3	C0085584
Disease	Adenocarcinoma of lung (disorder)	OGG1 ACSL4 TNK2 KDR PRKDC ENO1	1.85e-04	206	118	6	C0152013
Disease	hypopituitarism (implicated_via_orthology)	EIF2S3B EIF2S3	2.35e-04	6	118	2	DOID:9406 (implicated_via_orthology)
Disease	Mental Retardation, X-Linked 1	ACSL4 ARHGEF6 ALG13	2.84e-04	32	118	3	C2931498
Disease	middle cerebral artery infarction (biomarker_via_orthology)	APAF1 CASP6 OGG1 AGER	5.39e-04	93	118	4	DOID:3525 (biomarker_via_orthology)
Disease	leukodystrophy (implicated_via_orthology)	EIF2S3B EIF2S3	5.60e-04	9	118	2	DOID:10579 (implicated_via_orthology)
Disease	epilepsy (is_implicated_in)	CP KCNB1	5.60e-04	9	118	2	DOID:1826 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_marker_for)	APAF1 CASP6 NR3C1 AGER KDR	6.03e-04	169	118	5	DOID:3908 (is_marker_for)
Disease	chronic obstructive pulmonary disease (is_marker_for)	NR3C1 AGER KDR CXCL11	6.32e-04	97	118	4	DOID:3083 (is_marker_for)
Disease	fructose measurement, glucose measurement, galactose measurement	SMOC1 DSCAML1	1.02e-03	12	118	2	EFO_0004468, EFO_0010477, EFO_0010481
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	F5 ATP1B1	1.20e-03	13	118	2	EFO_0802114
Disease	Mental Retardation, X-Linked Nonsyndromic	ACSL4 ARHGEF6	1.20e-03	13	118	2	C3501611
Disease	systemic scleroderma (is_marker_for)	CXCR6 AGER KDR	1.26e-03	53	118	3	DOID:418 (is_marker_for)
Disease	Polydactyly	DYNC2H1 SMOC1 HNRNPK TRIM32	1.27e-03	117	118	4	C0152427
Disease	peripheral arterial disease	SMOC1 CSMD3 F5	1.33e-03	54	118	3	EFO_0004265
Disease	phoneme awareness	DDX27 KCNB1	1.40e-03	14	118	2	EFO_0021812
Disease	calcium/calmodulin-dependent protein kinase type 1 measurement	F5 ATP1B1	1.83e-03	16	118	2	EFO_0008062
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	DIP2B SETD2	2.07e-03	17	118	2	DOID:0060307 (is_implicated_in)
Disease	essential hypertension (is_implicated_in)	SLC12A3 ATP1B1	2.33e-03	18	118	2	DOID:10825 (is_implicated_in)
Disease	coagulation factor V measurement	F5 ATP1B1	2.87e-03	20	118	2	EFO_0008087
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	FNBP1 RNF213 KCNB1	2.92e-03	71	118	3	EFO_0004735, EFO_0007965
Disease	Deep Vein Thrombosis	F5 KDR	3.17e-03	21	118	2	C0149871
Disease	Venous Thrombosis	F5 KDR	3.17e-03	21	118	2	C0042487
Disease	cholangiocarcinoma (is_implicated_in)	OGG1 ASPH	3.48e-03	22	118	2	DOID:4947 (is_implicated_in)
Disease	Corneal astigmatism	PHF19 SYT17 HERC2	3.68e-03	77	118	3	EFO_1002040
Disease	Unipolar Depression	APAF1 NR3C1 ACSL4 KDR KPNA3	3.92e-03	259	118	5	C0041696

Protein segments in the cluster

Peptide	Gene	Start	Entry
FQKLCGLKPLVGVVD	TDRD5	611	Q8NAT2
GKITLVSAAPGKVIC	ACOT13	26	Q9NPJ3
CPKVIGVKLTGSLSG	ACO2	226	Q99798
GDKRCKLLLGIGILV	BST2	16	Q10589
GRVGAPLICCEIKLK	ACSL4	486	O60488
ECKGSPLVVSLIGAL	APAF1	316	O14727
ACLEGKSPGEKVAII	BRAP	46	Q7Z569
EGKPCIIIKLNRVLG	ATP1B1	171	P05026
CLETLEKGKPLVVVI	ALG13	86	Q9NP73
LISLGVLESPKKTIC	ARHGEF6	11	Q15052
KLVKDIGCLPYLGVS	CXCR6	301	O00574
IVPCGGILTKRKGTI	CSMD3	1936	Q7Z407
GKVPICEAGSKILVK	CSMD3	3461	Q7Z407
ALPKLGICAGLQVVL	ALG3	231	Q92685
TGCILRKLDGKIVLP	SPATA5	161	Q8NB90
VTLELGGKSPCIVLA	ALDH1A1	266	P00352
LGLVIPKEGCKIRCA	ASPH	691	Q12797
GCPVLALEVLSKIPK	DMXL2	1896	Q8TDJ6
PICVSALLLGILGIK	ALG14	151	Q96F25
KACIPVGLLGKDICA	DDX27	246	Q96GQ7
GQGTVCLLPSKEVIK	ATP2C2	411	O75185
GKLLVEPDVKGVPCV	ASXL3	1846	Q9C0F0
GPCILPIVRDGKKVS	TNK2	841	Q07912
SAPEKLIVGILGIIC	KLRC1	66	P26715
PELKATFCLPILGVK	NSA2	186	O95478
CIIRKIKAIGGIILT	PGM1	101	P36871
ITARIGEPLVLKCKG	AGER	26	Q15109
LKKEIGLVSACGIIV	SLC7A8	36	Q9UHI5
KEVIIITTAKLPCGK	ANKRD34B	146	A5PLL1
SGLIGPLIICKKDSL	CP	191	P00450
IIPAEGVGISQLLCK	MBD3L1	131	Q8WWY6
GKSISLLCLEGLQKI	FANCI	901	Q9NVI1
DFIITPGGCLKCKII	PARP15	361	Q460N3
IKSGILPILVKCLER	KPNA3	111	O00505
FGKVGCKLIPVIQLT	NMBR	111	P28336
LVLPVGGIKDKVLAA	LONP2	776	Q86WA8
EDLRKCKIIFIIGGP	AK5	371	Q9Y6K8
CVLKVVGLPLTGLNT	NLRP11	946	P59045
LVAGLKGLKVIDVAC	HERC2	596	O95714
GILKCLVLVSEPQVK	MMS22L	1116	Q6ZRQ5
LVGKPKIFIIQACRG	CASP6	151	P55212
KIPGEKDSVICLKGS	CD55	71	P08174
AKGTRLAKPVLCLGL	PLPPR5	216	Q32ZL2
AACLLDGVPVALKKV	NEK7	51	Q8TDX7
LLSESGKILPGVKVV	DIP2B	1361	Q9P265
LCTPGVIKQEKLGTV	NR3C1	286	P04150
AHKALCILPGVGTKV	OGG1	236	O15527
VGILCRGLLLPKVVE	PARP4	446	Q9UKK3
GCPLGLVLALRKTVI	PITPNM2	726	Q9BZ72
AKIVTLVPAGIKSLG	OC90	256	Q02509
TPKLLACLLGEEKTI	OR6M1	76	Q8NGM8
VLGLIAKTKQGCDIL	RICTOR	971	Q6R327
KDAGAIAGLKVLPII	HSPA7	161	P48741
SGGKPIAVLCLTVEL	NPHP4	1111	O75161
PALRIILVGKTGCGK	GIMAP5	26	Q96F15
AKLQIKISGLLLEGC	DYNC2H1	4211	Q8NCM8
KDGKLLPAITILGCR	GMPPA	376	Q96IJ6
LAVCKAGAVEKGVPL	ENO1	116	P06733
KTLLGKIVGGLCCIA	KCNB1	386	Q14721
AVGKILSEKLCLLQG	CARD14	836	Q9BXL6
VIPIIGKCLDGIVKA	FNBP1	241	Q96RU3
NQKPTVLELILKGCG	DMRT3	261	Q9NQL9
GDDVKKLFTIGCPVI	DSCAML1	1586	Q8TD84
TSPGLKCLLKKVSGI	ARFGEF3	1786	Q5TH69
TGVPGKKCGTILLTA	CPNE9	126	Q8IYJ1
VLIDLVTGKGPKSCC	CARD18	56	P57730
CIGSEKLLQKKPVGS	CCDC66	61	A2RUB6
IKGPLEIYQGICKIR	C6orf118	451	Q5T5N4
LKTLGPILKKIICDG	IFRD1	166	O00458
SSGLVGPLLVCKKGV	HEPHL1	551	Q6MZM0
PTICKIVGKDVLDGL	ENO4	66	A6NNW6
PLCRIIAKEGGVVAL	INSC	271	Q1MX18
RVLGKPLGLKDCIIV	DDX49	91	Q9Y6V7
LIGVGTKIDPTLCRA	EIF2S3B	336	Q2VIR3
EGQIKKIDGCTVIPL	FAM111B	581	Q6SJ93
VGIPGKKCGTIILTA	CPNE8	136	Q86YQ8
LCIGPGVKAVKVADI	CXCL11	31	O14625
CPGKIVLRALKESGA	POM121L1P	26	Q3SYA9
VDGLGQKVCRPVVLK	FAM181A	321	Q8N9Y4
GIALTPKGQLLVLDC	TRIM32	621	Q13049
GKVSVPLCEVDLVKG	SYT17	291	Q9BSW7
KLQEVIGKLKGLCPS	SYNE2	5336	Q8WXH0
IGKLKGLCPSVAEII	SYNE2	5341	Q8WXH0
KILPVLCGLTVDPEK	SCYL1	506	Q96KG9
TEGIPCLGSKVKGII	DNTT	211	P04053
LIGPLLICKKGTLTE	F5	186	P12259
KKDVLVPCLKAGHVG	NBR1	426	Q14596
GKVILGVIADLPCIS	SLC16A14	366	Q7RTX9
LCEGIFKVLIKDIPT	RIC8B	46	Q9NVN3
RVPKGEVGLLVCKIT	SLC27A2	416	O14975
KVKVILLLPRCSGLG	NSUN7	366	Q8NE18
GGKPDRVVECIKIIL	HNRNPK	196	P61978
IDIPKKGVAGLRLDC	RNF146	171	Q9NTX7
LDEILIGKIKGCSPE	POLR3H	81	Q9Y535
LLGTVSGELVDCLKP	INTS5	351	Q6P9B9
PCLKILLSKGLGLGI	MPDU1	36	O75352
GLCPDGKSILKITKV	CILP	266	O75339
ILPKCIGGEIEKTRI	ATP11B	601	Q9Y2G3
VVCIELKIPLFLVGK	RNF213	2756	Q63HN8
VAKAVLECKPLGIKT	RNF213	4341	Q63HN8
ISLPELKGCLGVSKE	SMOC1	416	Q9H4F8
LTLKETGLPKCVLSG	ELAC2	126	Q9BQ52
IPALVGKGCLILSDE	SPTLC2	246	O15270
DKAKGPGLILVLPCI	STOML3	71	Q8TAV4
SVCITIEPGLLLKGD	TNS1	231	Q9HBL0
IEPGLLLKGDILLKC	TNS1	236	Q9HBL0
KGALCQETILIIKAG	TEX101	56	Q9BY14
ICLGKTSGPLNEILI	PHF19	101	Q5T6S3
ALIVITLPIGRKGKC	SLC12A3	971	P55017
KPIVGRKICILGDCS	ELAC1	241	Q9H777
LGLVPSAVLIVAKKC	UBXN1	281	Q04323
LPPGIKVDSLTLLKC	SETD2	886	Q9BYW2
GLIRICSKPVVLPKG	PRKDC	486	P78527
SVGCSGIKPDVIFKL	ZNF630	46	Q2M218
DGLFCKTLTIPKVIG	KDR	81	P35968
PRVVDKLSLCVAPGK	TREX1	61	Q9NSU2
LKKLGCRIVGPQVVI	TOPBP1	71	Q92547
VTICGDLVALKLGIP	UGT2A2	161	P0DTE5
SQPCGLLKDVGLVKE	ZFYVE16	266	Q7Z3T8
VECAGPLLKALVGLV	TTI1	326	O43156
LIGVGTKIDPTLCRA	EIF2S3	336	P41091
KPITVGGKIVGSLCA	KCNA4	531	P22459
VIVVIGGCDRKGLLK	KLHL35	301	Q6PF15
GSGIVTRCPLVLKLK	MX2	146	P20592
AVPELKLLCGADVLK	NMNAT3	126	Q96T66