Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin filament binding	MYH6 SYNE1 SPTA1 TLN1 MYH15 TNNI3 SAMD14	1.76e-05	227	72	7	GO:0051015
GeneOntologyMolecularFunction	quaternary ammonium group binding	PITPNM2 ABCA1 NF1 ILVBL	2.26e-05	46	72	4	GO:0050997
GeneOntologyMolecularFunction	cytoskeletal protein binding	CEP350 MYH6 APPBP2 NF1 ANK2 ANK3 SYNE1 SPTA1 TLN1 ANKRD1 MYH15 TUBGCP2 TNNI3 SAMD14	3.21e-05	1099	72	14	GO:0008092
GeneOntologyMolecularFunction	phosphatidylcholine binding	PITPNM2 ABCA1 NF1	2.48e-04	34	72	3	GO:0031210
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK2 ANK3	5.66e-04	10	72	2	GO:0140031
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 MYH6 APPBP2 MYH15	8.75e-04	118	72	4	GO:0003774
GeneOntologyCellularComponent	myofibril	CAB39 MYH6 ANK2 ANK3 SYNE1 ANKRD1 MYH15 TNNI3	3.99e-06	273	71	8	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	CAB39 MYH6 ANK2 ANK3 SYNE1 ANKRD1 MYH15 TNNI3	6.22e-06	290	71	8	GO:0043292
GeneOntologyCellularComponent	sarcomere	CAB39 MYH6 ANK2 ANK3 SYNE1 ANKRD1 TNNI3	2.17e-05	249	71	7	GO:0030017
GeneOntologyCellularComponent	mitotic cohesin complex	STAG1 STAG2	2.36e-04	7	71	2	GO:0030892
GeneOntologyCellularComponent	I band	CAB39 MYH6 ANK2 ANK3 ANKRD1	2.54e-04	166	71	5	GO:0031674
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	ANK3 SPTA1	4.03e-04	9	71	2	GO:0014731
GeneOntologyCellularComponent	mitotic spindle pole	STAG1 TTC28 STAG2	4.20e-04	43	71	3	GO:0097431
GeneOntologyCellularComponent	cohesin complex	STAG1 STAG2	6.13e-04	11	71	2	GO:0008278
GeneOntologyCellularComponent	nuclear matrix	STAG1 SMARCC2 HES1 STAG2	1.32e-03	140	71	4	GO:0016363
GeneOntologyCellularComponent	transferase complex	CAB39 APPBP2 KMT2D UBR3 NAA30 FXN TEX10 VIRMA TADA3 ILVBL	1.48e-03	963	71	10	GO:1990234
Domain	OAR	ARX SHOX SHOX2	2.42e-05	15	72	3	PF03826
Domain	OAR	ARX SHOX SHOX2	2.97e-05	16	72	3	PS50803
Domain	OAR_dom	ARX SHOX SHOX2	2.97e-05	16	72	3	IPR003654
Domain	Staufen_C	STAU1 PRKRA	4.39e-05	3	72	2	IPR032478
Domain	Staufen_C	STAU1 PRKRA	4.39e-05	3	72	2	PF16482
Domain	STAG	STAG1 STAG2	8.75e-05	4	72	2	IPR013721
Domain	SCD	STAG1 STAG2	8.75e-05	4	72	2	PS51425
Domain	SCD	STAG1 STAG2	8.75e-05	4	72	2	IPR020839
Domain	STAG	STAG1 STAG2	8.75e-05	4	72	2	PF08514
Domain	ARM-type_fold	CAB39 NF1 ATR STAG1 TEX10 VIRMA STAG2	3.27e-04	339	72	7	IPR016024
Domain	ANK	TRANK1 ANK2 ANK3 ANKRD1 PPP1R16B ANKHD1	4.13e-04	251	72	6	SM00248
Domain	ANK_REPEAT	TRANK1 ANK2 ANK3 ANKRD1 PPP1R16B ANKHD1	4.31e-04	253	72	6	PS50088
Domain	Ankyrin_rpt-contain_dom	TRANK1 ANK2 ANK3 ANKRD1 PPP1R16B ANKHD1	4.40e-04	254	72	6	IPR020683
Domain	ANK_REP_REGION	TRANK1 ANK2 ANK3 ANKRD1 PPP1R16B ANKHD1	4.40e-04	254	72	6	PS50297
Domain	Ankyrin_rpt	TRANK1 ANK2 ANK3 ANKRD1 PPP1R16B ANKHD1	5.18e-04	262	72	6	IPR002110
Domain	ZU5	ANK2 ANK3	5.18e-04	9	72	2	SM00218
Domain	ARM-like	CAB39 NF1 ATR STAG1 TEX10 STAG2	6.07e-04	270	72	6	IPR011989
Domain	ZU5	ANK2 ANK3	6.46e-04	10	72	2	PS51145
Domain	ZU5	ANK2 ANK3	9.43e-04	12	72	2	PF00791
Domain	ZU5_dom	ANK2 ANK3	9.43e-04	12	72	2	IPR000906
Domain	-	APPBP2 TRANK1 ATR TTC28 P3H3	1.22e-03	207	72	5	1.25.40.10
Domain	Myosin_N	MYH6 MYH15	1.49e-03	15	72	2	PF02736
Domain	Myosin_N	MYH6 MYH15	1.49e-03	15	72	2	IPR004009
Domain	Ank	ANK2 ANK3 ANKRD1 PPP1R16B ANKHD1	1.87e-03	228	72	5	PF00023
Domain	HEAT_type_2	ATR TEX10	1.92e-03	17	72	2	IPR021133
Domain	TPR-like_helical_dom	APPBP2 TRANK1 ATR TTC28 P3H3	2.05e-03	233	72	5	IPR011990
Domain	Myosin_tail_1	MYH6 MYH15	2.15e-03	18	72	2	PF01576
Domain	Myosin_tail	MYH6 MYH15	2.15e-03	18	72	2	IPR002928
Domain	HTH_motif	ARX SHOX SHOX2	2.40e-03	69	72	3	IPR000047
Domain	DSRM	STAU1 PRKRA	2.40e-03	19	72	2	SM00358
Domain	Myosin-like_IQ_dom	MYH6 MYH15	2.40e-03	19	72	2	IPR027401
Domain	-	MYH6 MYH15	2.40e-03	19	72	2	4.10.270.10
Domain	dsrm	STAU1 PRKRA	2.66e-03	20	72	2	PF00035
Domain	-	TRANK1 ANK2 ANK3 ANKRD1 PPP1R16B	2.69e-03	248	72	5	1.25.40.20
Domain	TPR-contain_dom	APPBP2 TRANK1 TTC28 P3H3	2.69e-03	150	72	4	IPR013026
Domain	DS_RBD	STAU1 PRKRA	2.94e-03	21	72	2	PS50137
Domain	Spectrin	SYNE1 SPTA1	3.52e-03	23	72	2	PF00435
Domain	TPR_REGION	APPBP2 TRANK1 TTC28 P3H3	3.79e-03	165	72	4	PS50293
Domain	TPR	APPBP2 TRANK1 TTC28 P3H3	3.79e-03	165	72	4	PS50005
Domain	-	STAU1 PRKRA	4.83e-03	27	72	2	3.30.160.20
Domain	DEATH	ANK2 ANK3	4.83e-03	27	72	2	SM00005
Domain	dsRBD_dom	STAU1 PRKRA	5.19e-03	28	72	2	IPR014720
Domain	Spectrin_repeat	SYNE1 SPTA1	5.56e-03	29	72	2	IPR002017
Domain	Spectrin/alpha-actinin	SYNE1 SPTA1	6.75e-03	32	72	2	IPR018159
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PITPNM2 CAB39 SRRT MYH6 NF1 ANK2 ANK3 TRIM28 SYNE1 SPTA1 TLN1 MTMR2 SMARCC2 DHX29 VIRMA RUFY3 STAU1 PRKRA	6.57e-10	1431	73	18	37142655
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SRRT KMT2D NF1 ATR TRIM28 TBC1D2 ZBTB40 SMARCC2 TIMELESS CDT1 DHX29 VIRMA STAG2 PHLDB2	7.15e-10	774	73	14	15302935
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CEP350 SRRT TRAP1 NF1 STXBP2 TRIM28 SYNE1 TLN1 SMARCC2 TEX10 STAG2 PHLDB2 STAU1	1.95e-07	1024	73	13	24711643
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SRRT MIA3 NF1 TRIM28 SMARCC2 MPHOSPH10 TEX10 DHX29 STAU1	3.63e-07	440	73	9	34244565
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PITPNM2 TRAP1 MIA3 NF1 ANK2 ANK3 TRIM28 SMARCC2 UBR3 DHX29 RUFY3 STAU1 PRKRA	6.49e-07	1139	73	13	36417873
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK2 ANK3 SPTA1	1.05e-06	10	73	3	22159418
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NF1 TLN1 SMARCC2 MPHOSPH10 TEX10 ANKHD1 VIRMA STAG2 STAU1 PRKRA	1.09e-06	653	73	10	22586326
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 TRAP1 TLN1 NAA30 MPHOSPH10 ANKHD1 DHX29 TADA3 STAU1 PRKRA	2.74e-06	724	73	10	36232890
Pubmed	STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells.	STAG1 STAG2	4.35e-06	2	73	2	34648034
Pubmed	STAG Mutations in Cancer.	STAG1 STAG2	4.35e-06	2	73	2	31421907
Pubmed	Distinct and overlapping roles of STAG1 and STAG2 in cohesin localization and gene expression in embryonic stem cells.	STAG1 STAG2	4.35e-06	2	73	2	32778134
Pubmed	Somatic mutation of the cohesin complex subunit confers therapeutic vulnerabilities in cancer.	STAG1 STAG2	4.35e-06	2	73	2	29649003
Pubmed	Comparative transgenic analysis of enhancers from the human SHOX and mouse Shox2 genomic regions.	SHOX SHOX2	4.35e-06	2	73	2	23575226
Pubmed	Nuclear import and export signals of human cohesins SA1/STAG1 and SA2/STAG2 expressed in Saccharomyces cerevisiae.	STAG1 STAG2	4.35e-06	2	73	2	22715410
Pubmed	Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1.	STAG1 STAG2	4.35e-06	2	73	2	28430577
Pubmed	Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe.	ATR TIMELESS	4.35e-06	2	73	2	37144518
Pubmed	Cohesin subunits, STAG1 and STAG2, and cohesin regulatory factor, PDS5b, in oral squamous cells carcinomas.	STAG1 STAG2	4.35e-06	2	73	2	27341316
Pubmed	Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts.	STAG1 STAG2	4.35e-06	2	73	2	28691904
Pubmed	The SUMO (Small Ubiquitin-like Modifier) Ligase PIAS3 Primes ATR for Checkpoint Activation.	ATR PIAS3	4.35e-06	2	73	2	26565033
Pubmed	Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.	STAG1 STAG2	4.35e-06	2	73	2	22415365
Pubmed	Distinct functions of human cohesin-SA1 and cohesin-SA2 in double-strand break repair.	STAG1 STAG2	4.35e-06	2	73	2	24324008
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	4.35e-06	2	73	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	4.35e-06	2	73	2	25383926
Pubmed	Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells.	STAG1 STAG2	4.35e-06	2	73	2	19822671
Pubmed	Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice.	SHOX SHOX2	4.35e-06	2	73	2	27601064
Pubmed	STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.	STAG1 STAG2	4.35e-06	2	73	2	32467316
Pubmed	Specialized functions of cohesins STAG1 and STAG2 in 3D genome architecture.	STAG1 STAG2	4.35e-06	2	73	2	32294612
Pubmed	Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation.	STAG1 STAG2	4.35e-06	2	73	2	31495782
Pubmed	Precocious chondrocyte differentiation disrupts skeletal growth in Kabuki syndrome mice.	KMT2D SHOX2	4.35e-06	2	73	2	31557133
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	SRRT ATR PIAS3 STAG1 TRIM28 SMARCC2 TEX10 TADA3	4.99e-06	453	73	8	29656893
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MIA3 NF1 ANK2 ANK3 TRIM28 SYNE1 SMARCC2 FRMPD3 TEX10 VIRMA PHLDB2	5.15e-06	963	73	11	28671696
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	SYNE1 SMARCC2 MPHOSPH10 TEX10 DHX29 STAU1 PRKRA	6.44e-06	332	73	7	25693804
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	PITPNM2 SRRT NF1 STAG1 TUBGCP2 DHX29 STAU1 PRKRA	7.05e-06	475	73	8	31040226
Pubmed	Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.	NF1 ANK3 SMARCC2	7.08e-06	18	73	3	33323119
Pubmed	Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.	MYH6 ANKRD1 TNNI3	8.39e-06	19	73	3	30700554
Pubmed	QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.	ANK3 ANKRD1 TNNI3	9.86e-06	20	73	3	33397958
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 KMT2D SYNE1 SMARCC2 VIRMA STAU1	1.02e-05	234	73	6	36243803
Pubmed	Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.	MYH6 TNNI3	1.30e-05	3	73	2	18362229
Pubmed	Single-molecule imaging reveals a direct role of CTCF's zinc fingers in SA interaction and cluster-dependent RNA recruitment.	STAG1 STAG2	1.30e-05	3	73	2	38742641
Pubmed	Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications.	STAG1 STAG2	1.30e-05	3	73	2	24335498
Pubmed	Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts.	ATR TIMELESS	1.30e-05	3	73	2	23255133
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	1.30e-05	3	73	2	15611082
Pubmed	Characterization of the interaction between the cohesin subunits Rad21 and SA1/2.	STAG1 STAG2	1.30e-05	3	73	2	23874961
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	1.30e-05	3	73	2	33410423
Pubmed	Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2.	STAG1 STAG2	1.30e-05	3	73	2	36898992
Pubmed	ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene.	TLN1 ANKRD1	1.30e-05	3	73	2	19608030
Pubmed	A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.	STAU1 PRKRA	1.30e-05	3	73	2	20064372
Pubmed	Checkpoint kinase ATR phosphorylates Cdt2, a substrate receptor of CRL4 ubiquitin ligase, and promotes the degradation of Cdt1 following UV irradiation.	ATR CDT1	1.30e-05	3	73	2	23029527
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	1.30e-05	3	73	2	34289389
Pubmed	The effects of slow skeletal troponin I expression in the murine myocardium are influenced by development-related shifts in myosin heavy chain isoform.	MYH6 TNNI3	1.30e-05	3	73	2	22966157
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CEP350 MIA3 ANK3 NAA30 TUBGCP2 PHLDB2	1.51e-05	251	73	6	29778605
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	STXBP2 STAG1 TRIM28 TIMELESS ANKHD1 DHX29 VIRMA STAU1 PRKRA	1.66e-05	704	73	9	29955894
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NEK1 KMT2D ANK3 TTC28 TRIM28 TLN1 NAA30 ANKHD1	2.00e-05	549	73	8	38280479
Pubmed	Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation.	MYH6 SHOX2 TNNI3	2.50e-05	27	73	3	24335256
Pubmed	Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity.	NEK1 ATR	2.60e-05	4	73	2	28426283
Pubmed	Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.	ATR TIMELESS	2.60e-05	4	73	2	19805627
Pubmed	SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs.	STAG1 STAG2	2.60e-05	4	73	2	9305759
Pubmed	Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.	MYH6 TNNI3	2.60e-05	4	73	2	11815426
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CEP350 SRRT TRAP1 ANK2 TLN1 SMARCC2 VARS2 TEX10 ANKHD1 VIRMA STAU1 PRKRA	2.67e-05	1371	73	12	36244648
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TRAP1 NF1 ATR STAG1 TLN1 SMARCC2 TUBGCP2 STAG2	3.03e-05	582	73	8	20467437
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	MIA3 ATR P3H3 TIMELESS ANKHD1 RUFY3	3.09e-05	285	73	6	32838362
Pubmed	Functional proteomics mapping of a human signaling pathway.	KMT2D MAST4 ANK3 PIAS3 STAG1 MPHOSPH10 TEX10 STAU1	3.38e-05	591	73	8	15231748
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 SRRT TRAP1 NF1 ATR TRIM28 SYNE1 TLN1 ANKHD1 DHX29 STAG2 STAU1	3.88e-05	1425	73	12	30948266
Pubmed	Dilated Cardiomyopathy Overview	MYH6 ANKRD1 TNNI3	4.21e-05	32	73	3	20301486
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MIA3 NF1 TTC28 TUBGCP2 ILVBL RUFY3 PHLDB2	4.28e-05	446	73	7	24255178
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	ANK2 ANK3	4.33e-05	5	73	2	25950943
Pubmed	NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response.	NEK1 ATR	4.33e-05	5	73	2	15604234
Pubmed	Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function.	SHOX SHOX2	4.33e-05	5	73	2	21454626
Pubmed	STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis.	STAG1 STAG2	4.33e-05	5	73	2	12034751
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK2 ANK3	4.33e-05	5	73	2	25362471
Pubmed	Chk1 and Claspin potentiate PCNA ubiquitination.	ATR TIMELESS	4.33e-05	5	73	2	18451105
Pubmed	Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes.	STAG1 STAG2	4.33e-05	5	73	2	10931856
Pubmed	Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling.	NEK1 ATR	4.33e-05	5	73	2	23345434
Pubmed	T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.	ANK2 SPTA1	4.33e-05	5	73	2	29720258
Pubmed	Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue Homeostasis.	STAG1 STAG2	4.33e-05	5	73	2	32783938
Pubmed	Coding sequence rare variants identified in MYBPC3, MYH6, TPM1, TNNC1, and TNNI3 from 312 patients with familial or idiopathic dilated cardiomyopathy.	MYH6 TNNI3	4.33e-05	5	73	2	20215591
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK2 ANK3	4.33e-05	5	73	2	19109891
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH6 TRAP1 STXBP2 ANK2 STAG1 SYNE1 SPTA1 SMARCC2 MYH15 MPHOSPH10 TEX10 STAG2	4.36e-05	1442	73	12	35575683
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CEP350 KMT2D TBC1D2 PHLDB2 STAU1	4.41e-05	184	73	5	32908313
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRRT TRIM28 SYNE1 MPHOSPH10 ANKHD1 DHX29 VIRMA STAU1 PRKRA	4.81e-05	807	73	9	22681889
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	TRAP1 MIA3 ANK3 TRIM28 SYNE1 SPTA1 TLN1 SMARCC2 STAU1	4.81e-05	807	73	9	30575818
Pubmed	Hypertrophic Cardiomyopathy Overview	MYH6 ANKRD1 TNNI3	5.07e-05	34	73	3	20301725
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	TRIM28 SPTA1 TLN1 VIRMA PHLDB2	5.13e-05	190	73	5	15161933
Pubmed	Affinity purification strategies for proteomic analysis of transcription factor complexes.	STAG1 TRIM28 SMARCC2 TEX10	5.34e-05	97	73	4	23937658
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	CEP350 KMT2D NF1 TTC28 SMARCC2 MPHOSPH10 VIRMA STAG2	5.78e-05	638	73	8	31182584
Pubmed	The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication.	STAU1 PRKRA	6.48e-05	6	73	2	23853584
Pubmed	Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.	STAG1 STAG2	6.48e-05	6	73	2	15737063
Pubmed	Analysis of erythrocyte and platelet membrane proteins in various forms of beta-thalassemia.	ANK2 SPTA1	6.48e-05	6	73	2	15310273
Pubmed	Protein requirements for sister telomere association in human cells.	STAG1 STAG2	6.48e-05	6	73	2	17962804
Pubmed	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	TRANK1 ANK3	6.48e-05	6	73	2	22182935
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	ANK2 ANK3	6.48e-05	6	73	2	23728480
Pubmed	Cryo-EM structure of the human cohesin-NIPBL-DNA complex.	STAG1 STAG2	6.48e-05	6	73	2	32409525
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TTC28 TLN1 MTMR2 ANKHD1	7.01e-05	104	73	4	10470851
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CEP350 ANK2 ANK3 PIAS3 STAG1 TTC28 SYNE1 MTMR2 PPP1R16B RUFY3 PRKRA	7.31e-05	1285	73	11	35914814
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	KMT2D NF1 TIMELESS ANKHD1	7.55e-05	106	73	4	31024071
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CEP350 NEK1 MIA3 MAST4 TTC28	8.05e-05	209	73	5	36779422
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	CAB39 ANK2 SYNE1 TLN1 ANKRD1 ZBTB40 STAG2	8.43e-05	497	73	7	23414517
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	STAG1 TEX10 DHX29 STAG2 ILVBL RUFY3 PRKRA	8.53e-05	498	73	7	36634849
Pubmed	Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.	PIAS3 ANKRD1 TNNI3	8.93e-05	41	73	3	18157088
Pubmed	HCC-associated protein HCAP1, a variant of GEMIN4, interacts with zinc-finger proteins.	SRRT PIAS3	9.06e-05	7	73	2	12869526
Interaction	KCTD13 interactions	PITPNM2 CAB39 SRRT MYH6 NF1 ANK2 ANK3 TRIM28 SYNE1 SPTA1 TLN1 MTMR2 SMARCC2 DHX29 VIRMA RUFY3 STAU1 PRKRA	1.35e-06	1394	72	18	int:KCTD13
Interaction	HDAC1 interactions	SRRT NEK1 KMT2D ATR PIAS3 STAG1 TTC28 TRIM28 TLN1 SMARCC2 HES1 ANKHD1 VIRMA STAG2 STAU1	6.93e-06	1108	72	15	int:HDAC1
Interaction	VPS33B interactions	CEP350 MIA3 ANK3 TRIM28 NAA30 PHLDB2 STAU1	7.05e-06	199	72	7	int:VPS33B
Cytoband	9q31.1	MRPL50 ABCA1 TEX10	3.94e-05	41	73	3	9q31.1
GeneFamily	Ankyrin repeat domain containing	TRANK1 ANK2 ANK3 ANKRD1 PPP1R16B ANKHD1	6.57e-05	242	52	6	403
GeneFamily	Cohesin complex	STAG1 STAG2	2.25e-04	8	52	2	1060
GeneFamily	Myosin heavy chains	MYH6 MYH15	8.32e-04	15	52	2	1098
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	TRIM28 PPP1R16B MPHOSPH10 STAU1	1.81e-03	181	52	4	694
GeneFamily	PRD class homeoboxes and pseudogenes	ARX SHOX SHOX2	2.35e-03	92	52	3	521
GeneFamily	Phosphoinositide phosphatases	INPP5B MTMR2	3.81e-03	32	52	2	1079
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	MAST4 ANK3 SYNE1 PPP1R16B TIMELESS PHLDB2	6.63e-07	188	73	6	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	MYH6 MAST4 ANK2 ANK3 ANKRD1 TNNI3	7.27e-07	191	73	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	MYH6 MAST4 ANK2 ANK3 ANKRD1 TNNI3	7.50e-07	192	73	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	MYH6 MAST4 ANK2 ANK3 ANKRD1 TNNI3	8.21e-07	195	73	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	PTPRB PPP1R16B FXN TNNI3 C2CD4C	6.80e-06	161	73	5	1973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	MAST4 ANK2 ANK3 ANKRD1 TNNI3	1.30e-05	184	73	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MAST4 ANK2 ANK3 ANKRD1 TNNI3	1.33e-05	185	73	5	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.37e-05	186	73	5	facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.40e-05	187	73	5	cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.40e-05	187	73	5	b426a67b5669019115b58295ce7d304beeb75825
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	MAST4 ANK2 ANK3 ANKRD1 PHLDB2	1.48e-05	189	73	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 MAST4 ANK3 SYNE1 PPP1R16B	1.52e-05	190	73	5	55df73c8b696967a925b1772631f6900eff0fa30
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	MAST4 ANK2 ANK3 ANKRD1 PHLDB2	1.52e-05	190	73	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	PITPNM2 PTPRB MAST4 MAOA SYNE1	1.52e-05	190	73	5	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 MAST4 ANK3 SYNE1 PPP1R16B	1.52e-05	190	73	5	494fbab37305a7f92cddec75b291d42282555f5f
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	MYH6 MAST4 ANK2 ANK3 TNNI3	1.52e-05	190	73	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.52e-05	190	73	5	600b9674197f743dea1d19d3df0fc993b6e6aa25
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	MYH6 MAST4 ANK2 ANK3 TNNI3	1.56e-05	191	73	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	PITPNM2 PTPRB MAOA TTC28 SYNE1	1.56e-05	191	73	5	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PITPNM2 PTPRB TTC28 PPP1R16B HES1	1.59e-05	192	73	5	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.59e-05	192	73	5	c5f77c2103841505d13e09173549811312ef2f01
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.59e-05	192	73	5	e981162f387a31111c0ae8355dbe9db5785c4838
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.59e-05	192	73	5	97c312c82ec025c13052f8d424b11c0034c8ea54
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 ANK3 STAG1 TTC28 RUFY3	1.59e-05	192	73	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 SYNE1 PAQR8 SHOX	1.59e-05	192	73	5	3b0a52e4e77ae4539a034dcb419773b8e2aa5d51
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	MYH6 MAST4 ANK2 ANK3 ANKRD1	1.63e-05	193	73	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	MYH6 MAST4 ANK2 ANK3 ANKRD1	1.68e-05	194	73	5	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRB SYNE1 PPP1R16B CLDN15	1.68e-05	194	73	5	ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	MYH6 MAST4 ANK2 ANK3 ANKRD1	1.68e-05	194	73	5	c3535f7cc0076653c72db582047cff053c322397
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRB SYNE1 PPP1R16B CLDN15	1.76e-05	196	73	5	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRB SYNE1 PPP1R16B CLDN15	1.76e-05	196	73	5	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRB SYNE1 PPP1R16B CLDN15	1.76e-05	196	73	5	473980c827443464d08a0be28c53e3536369b12a
ToppCell	Severe_COVID-19-T/NK-NK\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	PITPNM2 TRANK1 SYNE1 PPP1R16B CDT1	1.80e-05	197	73	5	cc20162892b59e48653981f91fc9a0c27064444d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRB TTC28 PPP1R16B CLDN15	1.85e-05	198	73	5	b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NF1 ANK3 STAG1 TTC28 UBR3	1.89e-05	199	73	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Severe-Lymphoid-NK-Proliferating_T\|Severe / Condition, Lineage, Cell class and cell subclass	PITPNM2 P3H3 PPP1R16B PHLDB2	1.39e-04	160	73	4	cb2276d9bd78508644420e9580d3c17b914224cb
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PITPNM2 DNHD1 ANK3 NSUN7	1.45e-04	162	73	4	8e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAST4 MAOA ANK3 ARX	1.45e-04	162	73	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PITPNM2 DNHD1 ANK3 NSUN7	1.45e-04	162	73	4	e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH6 ANKRD1 SHOX2 TNNI3	1.60e-04	166	73	4	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH6 ANKRD1 SHOX2 TNNI3	1.60e-04	166	73	4	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	SEMA3D PTPRB ANK2 PPP1R16B	1.60e-04	166	73	4	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	PIAS3 TRIM28 SAMD14 C2CD4C	1.63e-04	167	73	4	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPP1R16B TIMELESS CDT1 C2CD4C	1.67e-04	168	73	4	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 ANK2 ANKRD1 TNNI3	1.75e-04	170	73	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH6 ANKRD1 GRID2 TNNI3	1.75e-04	170	73	4	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 ANKRD1 FXN TNNI3	1.75e-04	170	73	4	d99f61aa85ea3f775165cb433421e6f1cda4f96b
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	ABCA1 ANK3 ANKRD1 PHLDB2	1.75e-04	170	73	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH6 ANKRD1 GRID2 TNNI3	1.75e-04	170	73	4	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 ANKRD1 FXN TNNI3	1.75e-04	170	73	4	615cf9639c66b3fbd984ebe3f345280005d3c38a
ToppCell	NS-critical-LOC-Lymphoid-NK\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PITPNM2 SYNE1 PPP1R16B PHLDB2	1.79e-04	171	73	4	adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3D PTPRB SYNE1 PPP1R16B	1.83e-04	172	73	4	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel\|Adult / Lineage, Cell type, age group and donor	PTPRB SPTA1 PPP1R16B C2CD4C	1.83e-04	172	73	4	ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB PPP1R16B MYH15 NSUN7	1.91e-04	174	73	4	fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB PPP1R16B MYH15 NSUN7	1.91e-04	174	73	4	1f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB PPP1R16B MYH15 NSUN7	1.91e-04	174	73	4	ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	ABCA1 ANKRD1 TBC1D2 PHLDB2	1.91e-04	174	73	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRANK1 ANK3 MTMR2 ILVBL	1.95e-04	175	73	4	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	facs-Pancreas-Endocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB PPP1R16B CLDN15 TIMELESS	2.00e-04	176	73	4	9ddf87e586d2378984cd007c60f7dc254845f8f3
ToppCell	facs-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB PPP1R16B CLDN15 TIMELESS	2.00e-04	176	73	4	e987e741fcf1bed8598a5060700efd3018f8123b
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 ANK2 ANKRD1 TNNI3	2.00e-04	176	73	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH6 ANKRD1 SHOX2 TNNI3	2.00e-04	176	73	4	4ed73c73972334f6dc4229920205547823252fa0
ToppCell	facs-Pancreas-Endocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB PPP1R16B CLDN15 TIMELESS	2.00e-04	176	73	4	92ebcea9b2b22601234b76d7a98f0410b905a87b
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB STAG1 SYNE1 STAG2	2.08e-04	178	73	4	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	SEMA3D PTPRB PPP1R16B C2CD4C	2.08e-04	178	73	4	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PITPNM2 PTPRB PPP1R16B HES1	2.17e-04	180	73	4	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	severe-CD8+_T_naive\|severe / disease stage, cell group and cell class	DNHD1 NEK1 ANK3 PRKRA	2.17e-04	180	73	4	94fe530367b170777f4051a4034cff06d80dbb83
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 ANK2 ANKRD1 TNNI3	2.22e-04	181	73	4	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	HSPCs-Erythroblasts\|World / Lineage and Cell class	SPTA1 CDT1 FXN SAMD14	2.22e-04	181	73	4	ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PTPRB MAOA PPP1R16B TIMELESS	2.22e-04	181	73	4	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TRANK1 MAST4 ANK3 VIRMA	2.27e-04	182	73	4	1aea96ee211f7b9caef7fd385233f51be6021a73
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3D SYNE1 ANKRD1 PHLDB2	2.27e-04	182	73	4	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRANK1 MAST4 ANK3 VIRMA	2.27e-04	182	73	4	b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 MAST4 ANK3 VIRMA	2.27e-04	182	73	4	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRANK1 MAST4 ANK3 VIRMA	2.27e-04	182	73	4	4cb182ef39be2044a6ad7266f332d4177591e550
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Mild / Disease group, lineage and cell class	TRANK1 MAST4 ANK3 VIRMA	2.32e-04	183	73	4	7717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MAST4 TLN1 TNNI3 SAMD14	2.32e-04	183	73	4	6cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK2 ANK3 TLN1 PPP1R16B	2.32e-04	183	73	4	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	facs-Heart-RA-18m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 ANKRD1 FRMPD3 TNNI3	2.36e-04	184	73	4	72b42dfca7e9c0257f11d8242531e843271871a7
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3D SYNE1 ANKRD1 PHLDB2	2.36e-04	184	73	4	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	facs-Heart-RA-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 ANKRD1 FRMPD3 TNNI3	2.36e-04	184	73	4	c6f4537ae8b6e8fde1be17df14629b7b49b4997c
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 ANK2 ANKRD1 TNNI3	2.36e-04	184	73	4	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 ANK2 ANKRD1 TNNI3	2.41e-04	185	73	4	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	droplet-Marrow-nan-18m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 CDT1 FXN SAMD14	2.41e-04	185	73	4	a45756f91b62cf0fac3582786e5868deb8fd8435
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TTC28 SYNE1 PAQR8 SHOX	2.41e-04	185	73	4	0382bfbc96c23403b18fe439d8070ea9a7d29fd2
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 TLN1 ARX PHLDB2	2.41e-04	185	73	4	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D ABCA1 PTPRB ANKRD1	2.41e-04	185	73	4	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 PTPRB PPP1R16B PHLDB2	2.46e-04	186	73	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	MYH6 ANK2 ANK3 ANKRD1	2.57e-04	188	73	4	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 SPTA1 VARS2 TNNI3	2.57e-04	188	73	4	40ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAST4 TTC28 PAQR8 SHOX	2.57e-04	188	73	4	2b630b0609d4ac61338d6533cb7893cfe1241e44
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 SPTA1 VARS2 TNNI3	2.57e-04	188	73	4	ba7f7ce034c0f42742bf2461f68f8d343ee593a5
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 MIA3 ANK2 TTC28	2.57e-04	188	73	4	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA3D P3H3 SHOX2 SAMD14	2.57e-04	188	73	4	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3D PTPRB PPP1R16B HES1	2.62e-04	189	73	4	c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 CDT1 FXN SAMD14	2.62e-04	189	73	4	16dfc37d8d390ed7f927bc844c47c9c5a89a0928
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 CDT1 FXN SAMD14	2.62e-04	189	73	4	3ade3fa9369e85304b20d7233b581f18ad5ecc89
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH6 ANK2 ANKRD1 TNNI3	2.67e-04	190	73	4	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRPL50 TRAP1 TRIM28 CLDN15	2.67e-04	190	73	4	c0ee404d705b0b4f0c6ded4d070ad85eac4b16db
ToppCell	10x3'2.3-week_17-19-Hematopoietic-MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MAST4 TLN1 TNNI3 SAMD14	2.67e-04	190	73	4	64060e4b56ac9989e659c2d5d2a6b6edeba4d8d4
Drug	Thimerosal	CEP350 PITPNM2 MRPL50 MIA3 NF1 ANK2 MAOA STAG1 TRIM28 SMARCC2 HES1 CDT1 FRMPD3 TNNI3 TEX10 STAG2 PHLDB2	1.77e-07	1199	73	17	ctd:D013849
Drug	Protoveratrine A [143-57-7]; Down 200; 5uM; MCF7; HT_HG-U133A	NF1 MAST4 ANK3 MTMR2 SMARCC2 TUBGCP2 ILVBL RUFY3	2.26e-07	197	73	8	4963_DN
Drug	(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; HL60; HT_HG-U133A	TRANK1 ANK2 MAOA PPP1R16B SHOX2 TIMELESS RUFY3	2.41e-06	188	73	7	3046_UP
Drug	Estrone [53-16-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A	ABCA1 NF1 INPP5B TBC1D2 SHOX2 TIMELESS TUBGCP2	3.51e-06	199	73	7	6448_DN
Drug	Cephalothin sodium salt [58-71-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	MAST4 INPP5B SHOX2 CLDN15 TIMELESS TADA3 RUFY3	3.51e-06	199	73	7	6079_DN
Drug	PD-V	STAG1 SYNE1 STAG2	6.81e-06	12	73	3	CID000444615
Drug	Camptothecin	CAB39 ATR TRIM28 MTMR2 PPP1R16B FXN	1.41e-05	163	73	6	ctd:D002166
Drug	ZnBr2	SYNE1 ARX	3.04e-05	3	73	2	CID000024375
Drug	celecoxib; Up 200; 10uM; MCF7; HT_HG-U133A_EA	SRRT NF1 PTPRB MAOA TTC28 TBC1D2	3.24e-05	189	73	6	922_UP
Drug	Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; PC3; HT_HG-U133A	SRRT PTPRB P3H3 SYNE1 TLN1 TADA3	3.65e-05	193	73	6	4202_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	SRRT MAST4 P3H3 TLN1 CDT1 TADA3	3.65e-05	193	73	6	4338_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	SRRT NF1 P3H3 TLN1 CDT1 TADA3	3.75e-05	194	73	6	4331_DN
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A	NF1 MAOA P3H3 INPP5B TLN1 MYH15	3.75e-05	194	73	6	4335_DN
Drug	Betulin [473-98-3]; Down 200; 9uM; MCF7; HT_HG-U133A	ABCA1 STXBP2 ANK3 SHOX2 CLDN15 TIMELESS	3.86e-05	195	73	6	3513_DN
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; PC3; HT_HG-U133A	SRRT NF1 TBC1D2 SHOX2 TIMELESS TADA3	3.86e-05	195	73	6	6718_UP
Drug	Fluorometholone [426-13-1]; Down 200; 10.6uM; HL60; HT_HG-U133A	SRRT APPBP2 ABCA1 NF1 INPP5B MTMR2	3.86e-05	195	73	6	2509_DN
Drug	Pentoxifylline [6493-05-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A	SRRT NEK1 MAOA TLN1 TBC1D2 ZBTB40	3.86e-05	195	73	6	2290_DN
Drug	Benperidol [2062-84-2]; Down 200; 10.4uM; PC3; HT_HG-U133A	SRRT NF1 PTPRB P3H3 TLN1 TADA3	3.97e-05	196	73	6	4196_DN
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A	SRRT PTPRB P3H3 MTMR2 MYH15 TADA3	3.97e-05	196	73	6	4208_DN
Drug	Amodiaquin dihydrochloride dihydrate [6398-98-7]; Down 200; 8.6uM; HL60; HG-U133A	CEP350 NEK1 MIA3 STAG1 PPP1R16B STAU1	3.97e-05	196	73	6	1570_DN
Drug	Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A	SRRT NF1 INPP5B ZBTB40 CDT1 RUFY3	4.09e-05	197	73	6	5292_DN
Drug	Florfenicol [73231-34-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	SRRT ANK3 TLN1 ZBTB40 TUBGCP2 RUFY3	4.09e-05	197	73	6	5300_DN
Drug	5149715; Down 200; 10uM; MCF7; HT_HG-U133A_EA	NEK1 NF1 INPP5B ZBTB40 TUBGCP2 RUFY3	4.21e-05	198	73	6	890_DN
Drug	Mephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A	TRANK1 NF1 ANK3 TTC28 MTMR2 ZBTB40	4.21e-05	198	73	6	6275_UP
Drug	Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A	SRRT NF1 MAOA ZBTB40 CLDN15 TADA3	4.21e-05	198	73	6	2251_DN
Drug	O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate	SEMA3D MYH6 NF1 MAOA ANK3 ARX	5.99e-05	211	73	6	ctd:C009618
Drug	SA-3	STAG1 SYNE1 STAG2	9.78e-05	28	73	3	CID000657084
Drug	AC1L4NPY	STAG1 STAG2	1.01e-04	5	73	2	CID000160495
Drug	Sa-6	STAG1 STAG2	1.01e-04	5	73	2	CID000056560
Drug	Thiophosphonoacetic Acid	ANK2 MAOA ANK3 SPTA1	2.59e-04	96	73	4	CID005459392
Drug	aa 2	STAG1 SYNE1 STAG2	3.09e-04	41	73	3	CID000447622
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; PC3; HT_HG-U133A	NF1 PTPRB INPP5B HES1 RUFY3	3.30e-04	186	73	5	3819_DN
Drug	Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ABCA1 TIMELESS TUBGCP2 TADA3 RUFY3	3.56e-04	189	73	5	5254_DN
Drug	3-doxylandrostanol	ANK2 ANK3	3.60e-04	9	73	2	CID000189075
Drug	geldanamycin; Down 200; 1uM; PC3; HT_HG-U133A	INPP5B MYH15 HES1 CDT1 RUFY3	3.64e-04	190	73	5	4452_DN
Drug	Promazine hydrochloride [53-60-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A	NF1 MAST4 MTMR2 TIMELESS RUFY3	3.64e-04	190	73	5	3927_DN
Drug	Betazole hydrochloride; Up 200; 27uM; HL60; HT_HG-U133A	ABCA1 TBC1D2 PPP1R16B SHOX2 RUFY3	3.73e-04	191	73	5	1854_UP
Drug	Mesalamine [89-57-6]; Down 200; 26.2uM; HL60; HT_HG-U133A	NEK1 APPBP2 PPP1R16B DHX29 RUFY3	3.82e-04	192	73	5	6162_DN
Drug	2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A	NF1 TBC1D2 TUBGCP2 TADA3 RUFY3	3.91e-04	193	73	5	5600_UP
Drug	Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; PC3; HT_HG-U133A	SRRT PTPRB TLN1 MYH15 RUFY3	3.91e-04	193	73	5	4186_DN
Drug	Furosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A	NF1 MAST4 INPP5B CLDN15 RUFY3	3.91e-04	193	73	5	3197_DN
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A	NF1 MAST4 INPP5B TBC1D2 SHOX2	3.91e-04	193	73	5	3378_DN
Drug	Levodopa [59-92-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A	ABCA1 NF1 TTC28 TIMELESS TADA3	3.91e-04	193	73	5	4394_DN
Drug	Letrozole [112809-51-5]; Down 200; 14uM; PC3; HT_HG-U133A	SRRT PTPRB P3H3 TLN1 TADA3	3.91e-04	193	73	5	4240_DN
Drug	Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A	MAOA STAG1 SYNE1 TLN1 SMARCC2	3.91e-04	193	73	5	7364_DN
Drug	5707885; Up 200; 50uM; MCF7; HT_HG-U133A	SRRT ABCA1 INPP5B SHOX2 NSUN7	4.01e-04	194	73	5	6385_UP
Drug	Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; HL60; HT_HG-U133A	SRRT NEK1 TRANK1 SYNE1 PPP1R16B	4.01e-04	194	73	5	2434_DN
Drug	Skimmianine [83-95-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	SRRT NF1 MAST4 TADA3 RUFY3	4.01e-04	194	73	5	6066_DN
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A	NF1 TLN1 MTMR2 SHOX2 RUFY3	4.01e-04	194	73	5	3431_DN
Drug	Furaltadone hydrochloride [3759-92-0]; Up 200; 11uM; PC3; HT_HG-U133A	SRRT NF1 ANK2 SPTA1 TUBGCP2	4.10e-04	195	73	5	4313_UP
Drug	(-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA	PTPRB ANK2 P3H3 SYNE1 RUFY3	4.10e-04	195	73	5	874_UP
Drug	Molindone hydrochloride [15622-65-8]; Down 200; 12.8uM; PC3; HT_HG-U133A	SRRT PTPRB P3H3 TLN1 TADA3	4.10e-04	195	73	5	4199_DN
Drug	Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A	MIA3 NF1 TTC28 SHOX2 RUFY3	4.10e-04	195	73	5	5455_DN
Drug	Benzethonium chloride [121-54-0]; Up 200; 9uM; HL60; HT_HG-U133A	ABCA1 KMT2D ANK2 TBC1D2 TADA3	4.10e-04	195	73	5	2508_UP
Drug	Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	SEMA3D SHOX2 CLDN15 CDT1 TUBGCP2	4.10e-04	195	73	5	5115_UP
Drug	Tadjakonine [11087-94-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A	INPP5B SYNE1 TLN1 TIMELESS RUFY3	4.10e-04	195	73	5	2820_DN
Drug	Antipyrine [60-80-0]; Down 200; 21.2uM; PC3; HT_HG-U133A	PTPRB MAOA P3H3 TIMELESS TNNI3	4.10e-04	195	73	5	4251_DN
Drug	Nabumetone [42924-53-8]; Down 200; 17.6uM; MCF7; HT_HG-U133A	MIA3 NF1 MAST4 TTC28 TLN1	4.10e-04	195	73	5	5428_DN
Drug	prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A	NEK1 NF1 ANK3 P3H3 RUFY3	4.10e-04	195	73	5	6552_DN
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A	CEP350 MIA3 NF1 INPP5B TADA3	4.10e-04	195	73	5	5252_DN
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; PC3; HG-U133A	NEK1 ZBTB40 DHX29 ILVBL STAU1	4.10e-04	195	73	5	1934_DN
Drug	BAS 012416453; Up 200; 38uM; MCF7; HT_HG-U133A	MAST4 ANK3 TBC1D2 SHOX2 TUBGCP2	4.20e-04	196	73	5	6880_UP
Drug	Hydrocortisone base [50-23-7]; Down 200; 11uM; MCF7; HT_HG-U133A	NF1 MAST4 INPP5B TLN1 CLDN15	4.20e-04	196	73	5	3284_DN
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A	NEK1 APPBP2 MTMR2 ZBTB40 SMARCC2	4.20e-04	196	73	5	2005_DN
Drug	Benzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A	MIA3 NF1 MAST4 INPP5B TADA3	4.20e-04	196	73	5	5435_DN
Drug	Penbutolol sulfate [38363-32-5]; Down 200; 5.8uM; MCF7; HT_HG-U133A	SRRT ABCA1 NF1 STXBP2 CLDN15	4.20e-04	196	73	5	3534_DN
Drug	Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; MCF7; HT_HG-U133A	SRRT TLN1 SHOX2 MYH15 NSUN7	4.20e-04	196	73	5	2301_UP
Drug	Butylparaben [94-26-8]; Down 200; 20.6uM; HL60; HT_HG-U133A	ANK2 MAOA SYNE1 MTMR2 RUFY3	4.20e-04	196	73	5	3069_DN
Drug	Idoxuridine [54-42-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	PTPRB P3H3 TLN1 MYH15 TADA3	4.20e-04	196	73	5	4200_DN
Drug	Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A	NF1 STXBP2 TTC28 INPP5B RUFY3	4.20e-04	196	73	5	3422_DN
Drug	(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A	NF1 INPP5B SYNE1 MTMR2 TIMELESS	4.20e-04	196	73	5	2818_DN
Drug	Netilmicin sulfate [56931-57-2]; Down 200; 2.8uM; HL60; HT_HG-U133A	NF1 PIAS3 ZBTB40 SHOX2 RUFY3	4.20e-04	196	73	5	2963_DN
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A	NF1 MAOA INPP5B TBC1D2 ZBTB40	4.20e-04	196	73	5	2291_DN
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ABCA1 NF1 INPP5B SHOX2 TIMELESS	4.20e-04	196	73	5	4143_DN
Drug	Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	NEK1 ABCA1 INPP5B MTMR2 TUBGCP2	4.20e-04	196	73	5	6029_DN
Drug	Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A	ABCA1 TLN1 TBC1D2 TIMELESS RUFY3	4.20e-04	196	73	5	1536_UP
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A	NF1 MAST4 TTC28 TLN1 RUFY3	4.20e-04	196	73	5	7010_UP
Drug	Amitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; HL60; HT_HG-U133A	CEP350 APPBP2 PIAS3 MTMR2 ZBTB40	4.20e-04	196	73	5	1865_UP
Drug	Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A	ABCA1 MIA3 NF1 MAST4 TIMELESS	4.20e-04	196	73	5	3936_DN
Drug	Dydrogesterone [152-62-5]; Down 200; 12.8uM; PC3; HT_HG-U133A	ABCA1 PTPRB P3H3 SHOX2 TADA3	4.20e-04	196	73	5	4254_DN
Drug	Bemegride [64-65-3]; Up 200; 25.8uM; MCF7; HT_HG-U133A	NF1 TTC28 INPP5B CLDN15 RUFY3	4.20e-04	196	73	5	5014_UP
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A	SRRT NEK1 MTMR2 TIMELESS TUBGCP2	4.30e-04	197	73	5	3838_DN
Drug	Cetirizine dihydrochloride [83881-52-1]; Down 200; 8.6uM; PC3; HT_HG-U133A	SRRT NEK1 INPP5B SHOX2 TIMELESS	4.30e-04	197	73	5	4231_DN
Drug	Bretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A	MIA3 NF1 TTC28 TBC1D2 SHOX2	4.30e-04	197	73	5	3394_DN
Drug	Isoxicam [34552-84-6]; Up 200; 12uM; MCF7; HT_HG-U133A	CEP350 SRRT NEK1 MIA3 NF1	4.30e-04	197	73	5	1698_UP
Drug	Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; MCF7; HT_HG-U133A	NEK1 ABCA1 NF1 INPP5B SHOX2	4.30e-04	197	73	5	2887_DN
Drug	Apramycin [37321-09-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A	ABCA1 INPP5B TBC1D2 SHOX2 TIMELESS	4.30e-04	197	73	5	4959_UP
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	MIA3 SHOX2 CLDN15 TIMELESS TUBGCP2	4.30e-04	197	73	5	5025_DN
Drug	Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A	SRRT ABCA1 NF1 SHOX2 RUFY3	4.30e-04	197	73	5	6274_UP
Drug	Pyrimethamine [58-14-0]; Down 200; 16uM; PC3; HG-U133A	MAOA ATR CDT1 FXN TUBGCP2	4.30e-04	197	73	5	1894_DN
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MIA3 ANK3 MTMR2 ZBTB40 TUBGCP2	4.30e-04	197	73	5	5463_DN
Drug	Hydroflumethiazide [135-09-1]; Down 200; 12uM; MCF7; HT_HG-U133A	SRRT NF1 ZBTB40 TUBGCP2 RUFY3	4.30e-04	197	73	5	7019_DN
Drug	Piperacillin sodium salt [59703-84-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A	ABCA1 SYNE1 TBC1D2 SHOX2 RUFY3	4.30e-04	197	73	5	3939_UP
Drug	9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	NEK1 MAST4 TTC28 TADA3 RUFY3	4.30e-04	197	73	5	7500_UP
Drug	Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; PC3; HT_HG-U133A	SRRT TRANK1 NF1 TUBGCP2 TNNI3	4.30e-04	197	73	5	4620_UP
Drug	Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A	MAST4 STXBP2 INPP5B ZBTB40 CLDN15	4.30e-04	197	73	5	7208_DN
Drug	Deltaline [6836-11-9]; Down 200; 7.8uM; HL60; HT_HG-U133A	SRRT NEK1 SYNE1 SHOX2 RUFY3	4.30e-04	197	73	5	2171_DN
Drug	Ascorbic acid [50-81-7]; Up 200; 22.4uM; PC3; HT_HG-U133A	NF1 MAST4 TIMELESS CDT1 TADA3	4.30e-04	197	73	5	6306_UP
Drug	Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	SRRT NF1 MAOA SHOX2 RUFY3	4.30e-04	197	73	5	1693_UP
Drug	Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; HL60; HT_HG-U133A	CEP350 NF1 PTPRB INPP5B ZBTB40	4.30e-04	197	73	5	2353_UP
Disease	sick sinus syndrome (is_implicated_in)	MYH6 ANK2	5.36e-05	5	69	2	DOID:13884 (is_implicated_in)
Disease	Primary dilated cardiomyopathy	MYH6 ANKRD1 TNNI3	6.95e-05	34	69	3	cv:C0007193
Disease	Intellectual Disability	NF1 STAG1 SYNE1 ZBTB40 SMARCC2 STAG2 PRKRA	8.39e-05	447	69	7	C3714756
Disease	Idiopathic hypertrophic subaortic stenosis	MYH6 TNNI3	1.12e-04	7	69	2	C0700053
Disease	Obstructive asymmetric septal hypertrophy	MYH6 TNNI3	1.12e-04	7	69	2	C0597124
Disease	Glioblastoma Multiforme	SRRT NF1 HES1 STAG2	1.36e-04	111	69	4	C1621958
Disease	Familial dilated cardiomyopathy	MYH6 ANKRD1 TNNI3	1.51e-04	44	69	3	C0340427
Disease	Cardiomyopathy	MYH6 ANKRD1 TNNI3	1.84e-04	47	69	3	cv:C0878544
Disease	Cardiomyopathy, Hypertrophic, Familial	MYH6 TNNI3	1.92e-04	9	69	2	C0949658
Disease	myopathy (implicated_via_orthology)	MYH6 MTMR2 MYH15	1.96e-04	48	69	3	DOID:423 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:0110454 (implicated_via_orthology)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:0111269 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:0080719 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:0111602 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:0080326 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH6 MYH15	2.40e-04	10	69	2	DOID:0111596 (implicated_via_orthology)
Disease	Mental Retardation, Psychosocial	NF1 STAG1 ZBTB40 PRKRA	3.22e-04	139	69	4	C0025363
Disease	Profound Mental Retardation	NF1 STAG1 ZBTB40 PRKRA	3.22e-04	139	69	4	C0020796
Disease	Mental deficiency	NF1 STAG1 ZBTB40 PRKRA	3.22e-04	139	69	4	C0917816
Disease	Hypertrophic Cardiomyopathy	MYH6 ANKRD1 TNNI3	3.27e-04	57	69	3	C0007194
Disease	distal myopathy (implicated_via_orthology)	MYH6 MYH15	3.50e-04	12	69	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH6 MYH15	3.50e-04	12	69	2	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH6 MYH15	4.13e-04	13	69	2	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH6 MYH15	5.55e-04	15	69	2	DOID:0050646 (implicated_via_orthology)
Disease	cardiomyopathy (implicated_via_orthology)	MYH6 MYH15 TNNI3	6.24e-04	71	69	3	DOID:0050700 (implicated_via_orthology)
Disease	Pheochromocytoma, Extra-Adrenal	NF1 MAOA	6.33e-04	16	69	2	C1257877
Disease	Depression, Bipolar	TRANK1 MAOA ANK3	8.52e-04	79	69	3	C0005587
Disease	Glioblastoma	SRRT NF1 HES1	8.52e-04	79	69	3	C0017636
Disease	Bipolar Disorder	SRRT TRANK1 MAOA ANK3 SYNE1 TIMELESS	8.77e-04	477	69	6	C0005586
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH6 MYH15 TNNI3	8.84e-04	80	69	3	DOID:12930 (implicated_via_orthology)
Disease	Chronic myeloproliferative disorder	ATR CDT1	8.98e-04	19	69	2	C1292778
Disease	Pheochromocytoma	NF1 MAOA	8.98e-04	19	69	2	C0031511
Disease	Giant Cell Glioblastoma	SRRT NF1 HES1	1.02e-03	84	69	3	C0334588
Disease	Glioma	NF1 ATR STAG2	1.13e-03	87	69	3	C0017638
Disease	Seckel syndrome	ATR CDT1	1.21e-03	22	69	2	C0265202
Disease	hypertrophic cardiomyopathy (is_implicated_in)	ANKRD1 TNNI3	1.21e-03	22	69	2	DOID:11984 (is_implicated_in)
Disease	Primary familial hypertrophic cardiomyopathy	MYH6 TNNI3	1.21e-03	22	69	2	cv:C0949658
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	KMT2D NF1	1.32e-03	23	69	2	C1708353
Disease	bipolar disorder (is_implicated_in)	ANK3 SYNE1	2.10e-03	29	69	2	DOID:3312 (is_implicated_in)
Disease	Primary familial dilated cardiomyopathy	MYH6 TNNI3	2.25e-03	30	69	2	cv:C0340427

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSAHNRTKKHDLLRL	TADA3	356	O75528
KISARDKLLSTALHV	ANKRD1	211	Q15327
HLKLAKDSSADRFLN	ABCA1	1561	O95477
VKLDKAADLAHITAR	CDT1	521	Q9H211
ATFKDLLTRHKLLSA	CAB39	186	Q9Y376
DHLLLASSKRVKALI	APPBP2	371	Q92624
LQTALAEEKHKALRL	DNHD1	436	Q96M86
HLAAKLLDAKEQAAT	DHX29	266	Q7Z478
LAAESKSLLKAATRH	C2CD4C	96	Q8TF44
QLKKLDLAAAAAHTF	P3H3	166	Q8IVL6
LHIAARKDDTKSAAL	ANK2	196	Q01484
GFILARKADRLAKLH	MAOA	351	P21397
SLHELLAAELTKALK	FXN	181	Q16595
LADRDLLLIHKSLSK	PTPRB	501	P23467
RAALSKKVADLIHFL	MAGEA5P	106	P43359
ESLKAHANARAAVLK	NEK1	606	Q96PY6
VLLLANAFHKKLEDR	GRID2	331	O43424
KRLTLDHEKSKLSLA	MPHOSPH10	456	O00566
HIKLILAGALRIADK	MTMR2	391	Q13614
DKNFSAHLLDLLARL	TUBGCP2	826	Q9BSJ2
LRHKANFLKLLISEL	PITPNM2	1186	Q9BZ72
LELKRQRAAAKLLSH	PPP1R16B	481	Q96T49
ATAALLRHKVKARLT	PAQR8	336	Q8TEZ7
RLKSDLLKAALCHLL	ATR	336	Q13535
LHIRENRSAALKKAD	ILVBL	331	A1L0T0
FLAQHLNKDSLLARK	FRMPD3	831	Q5JV73
AHQSSLLRLREKALK	CEP350	1696	Q5VT06
LHIAARKDDTKAAAL	ANK3	206	Q12955
SRKAKLAATAGALHI	CLDN15	111	P56746
SLLKDALHKQASVRA	MAST4	1601	O15021
SIAALRLKAKEHAAQ	ARX	531	Q96QS3
AFLRELLKNSAKNHL	INPP5B	936	P32019
KELLRREKSNLAHSL	CROCCP3	61	Q8IVE0
ILDALKKDSSRHSKL	HES1	61	Q14469
LRALKHELAFKLQSS	RUFY3	401	Q7L099
LELSKLDKAASHLRQ	VARS2	1036	Q5ST30
LEDSRLKFNLLAHLA	MRPL50	91	Q8N5N7
TAVHLEALKKLALAL	SYNE1	4271	Q8NF91
KREAANLRHKLLELT	MIA3	1616	Q5JRA6
SASLKKRHADSLAEL	MYH15	1201	Q9Y2K3
DKSRSLAVHSVKALL	NSUN7	276	Q8NE18
ADLRLKAKKHAAALG	SHOX2	316	O60902
IADLRLKARKHAEAL	SHOX	276	O15266
LDSSLHKARAQLLAK	SAMD14	26	Q8IZD0
ASKDHLKRSLALAAA	SPESP1	256	Q6UW49
LKRSLALAAAAEHKL	SPESP1	261	Q6UW49
AAALRKKHADSVAEL	MYH6	1191	P13533
LLKQAHAEKTRLLES	PHLDB2	1041	Q86SQ0
LAAAAVKAKHLAAVE	SMARCC2	866	Q8TAQ2
AKDHIFLLSLVDLNK	SEMA3D	86	O95025
IKLAAKLIHTLDDRT	SRRT	521	Q9BXP5
SLLLDRKANVEHRAK	ANKHD1	1241	Q8IWZ3
SGRKHELLAKALHLL	PIAS3	31	Q9Y6X2
AQALRALLLAHKKKA	TIMELESS	1131	Q9UNS1
QAAKHDAAAKALRIL	STAU1	146	O95793
EASKIEALHKRRNLL	STAG2	851	Q8N3U4
LAKAVASAAAALVLK	TLN1	671	Q9Y490
LAHAVLAKLNAFKAD	STXBP2	201	Q15833
KKLFLDSLRKALAGH	NF1	296	P21359
IIHTAAARANKELLK	TEX10	576	Q9NXF1
ALHKRRNLLAAFSKL	STAG1	861	Q8WVM7
ALLKKHEAFLLDLNS	SPTA1	936	P02549
ARAKESLDLRAHLKQ	TNNI3	161	P19429
LAKHRAAEAAINILK	PRKRA	86	O75569
LALAKDLHDKLSQAK	TTC28	661	Q96AY4
LISNASDALEKLRHK	TRAP1	116	Q12931
LDKAATAAHLKAALS	UBR3	26	Q6ZT12
DARHRIKKNDSLLLA	TRANK1	586	O15050
LALLDALASHKACKL	VIRMA	1226	Q69YN4
LKLLAKIQALESRSH	TBC1D2	576	Q9BYX2
LASLVKRLGDKHATL	TRIM28	256	Q13263
RAHKLVLAAASLLFK	ZBTB40	36	Q9NUA8
SEAGHLLLQKLLRAK	KMT2D	4456	O14686
ELRHLRAAASLKSKV	NAA30	91	Q147X3