Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of adherens junction organization

RDX BMP6

8.38e-063352GO:1903392
GeneOntologyBiologicalProcessregulation of adherens junction organization

RDX BMP6

2.79e-055352GO:1903391
GeneOntologyCellularComponentcell division site

RDX SEPTIN5 ECT2 SEPTIN4

9.51e-0680354GO:0032153
GeneOntologyCellularComponentcleavage furrow

RDX SEPTIN5 ECT2

1.45e-0461353GO:0032154
GeneOntologyCellularComponentseptin complex

SEPTIN5 SEPTIN4

2.45e-0414352GO:0031105
GeneOntologyCellularComponentseptin ring

SEPTIN5 SEPTIN4

2.45e-0414352GO:0005940
GeneOntologyCellularComponentseptin cytoskeleton

SEPTIN5 SEPTIN4

3.22e-0416352GO:0032156
GeneOntologyCellularComponentactin cytoskeleton

FLII RDX PRKCB CDC42BPA NEB SEPTIN5

3.50e-04576356GO:0015629
GeneOntologyCellularComponentcell cortex

RDX PRKCB SEPTIN5 ECT2 SEPTIN4

3.59e-04371355GO:0005938
GeneOntologyCellularComponentneuron projection terminus

PRKCB PTBP1 SEPTIN5 SEPTIN4

6.00e-04233354GO:0044306
GeneOntologyCellularComponentcalyx of Held

PRKCB SEPTIN5

1.66e-0336352GO:0044305
DomainSeptin

SEPTIN5 SEPTIN4

2.63e-0413352PF00735
DomainG_SEPTIN_dom

SEPTIN5 SEPTIN4

2.63e-0413352IPR030379
DomainG_SEPTIN

SEPTIN5 SEPTIN4

2.63e-0413352PS51719
DomainSeptin

SEPTIN5 SEPTIN4

3.06e-0414352IPR016491
DomainPkinase_C

PRKCB CDC42BPA

2.18e-0337352IPR017892
DomainPkinase_C

PRKCB CDC42BPA

2.80e-0342352PF00433
DomainAGC-kinase_C

PRKCB CDC42BPA

4.93e-0356352IPR000961
DomainAGC_KINASE_CTER

PRKCB CDC42BPA

4.93e-0356352PS51285
DomainS_TK_X

PRKCB CDC42BPA

4.93e-0356352SM00133
DomainC1_1

PRKCB CDC42BPA

5.10e-0357352PF00130
DomainPkinase

SCYL1 PRKCB LRRK1 CDC42BPA

5.42e-03381354PF00069
DomainZF_DAG_PE_1

PRKCB CDC42BPA

6.39e-0364352PS00479
DomainZF_DAG_PE_2

PRKCB CDC42BPA

6.39e-0364352PS50081
DomainC1

PRKCB CDC42BPA

6.59e-0365352SM00109
DomainPE/DAG-bd

PRKCB CDC42BPA

6.79e-0366352IPR002219
Domainzf-C2H2

ZBTB37 ZNF81 ZNF280D ZBTB1 ZNF92

8.95e-03693355PF00096
Domain-

HS3ST5 LRRK1 SEPTIN5 SMC3 SEPTIN4

1.21e-027463553.40.50.300
DomainProt_kinase_dom

SCYL1 PRKCB LRRK1 CDC42BPA

1.28e-02489354IPR000719
DomainPROTEIN_KINASE_DOM

SCYL1 PRKCB LRRK1 CDC42BPA

1.31e-02493354PS50011
DomainZINC_FINGER_C2H2_2

ZBTB37 ZNF81 ZNF280D ZBTB1 ZNF92

1.40e-02775355PS50157
DomainZINC_FINGER_C2H2_1

ZBTB37 ZNF81 ZNF280D ZBTB1 ZNF92

1.42e-02777355PS00028
DomainZnf_C2H2-like

ZBTB37 ZNF81 ZNF280D ZBTB1 ZNF92

1.56e-02796355IPR015880
DomainZnf_C2H2

ZBTB37 ZNF81 ZNF280D ZBTB1 ZNF92

1.63e-02805355IPR007087
DomainZnF_C2H2

ZBTB37 ZNF81 ZNF280D ZBTB1 ZNF92

1.66e-02808355SM00355
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

XRN1 SCYL1 RDX API5 PTBP1 SEPTIN5 SMC3

5.62e-0749835736634849
Pubmed

Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol.

SEPTIN5 SEPTIN4

2.95e-06335215214843
Pubmed

The novel human platelet septin SEPT8 is an interaction partner of SEPT4.

SEPTIN5 SEPTIN4

2.95e-06335215116257
Pubmed

SEPT5_v2 is a parkin-binding protein.

SEPTIN5 SEPTIN4

5.90e-06435214559152
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

SCYL1 FLII CDC42BPA PTBP1 SMC3

7.83e-0627435534244482
Pubmed

Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.

SEPTIN5 SEPTIN4

9.82e-06535217296554
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

NEB SCN3A

9.82e-0653521679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

NEB SCN3A

9.82e-0653528812438
Pubmed

Differential localization of septins in the mouse brain.

SEPTIN5 SEPTIN4

2.06e-05735211064363
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

XRN1 FLII RDX NCOR1 API5 CDC42BPA PTBP1 SMC3

2.65e-05124735827684187
Pubmed

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.

SEPTIN5 SEPTIN4

3.53e-05935218809578
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

XRN1 RDX DENND5A C12orf56 ECT2 CWF19L1

4.26e-0565035638777146
Pubmed

The septin CDCrel-1 is dispensable for normal development and neurotransmitter release.

SEPTIN5 SEPTIN4

4.40e-051035211739749
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

XRN1 FLII CDC42BPA PTBP1

5.02e-0520235433005030
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NCOR1 DENND5A TBC1D14

9.34e-058735312465718
Pubmed

Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.

DENND5A ZBTB1

1.02e-041535219762545
Pubmed

Localization of septin proteins in the mouse cochlea.

SEPTIN5 SEPTIN4

1.17e-041635222575789
Pubmed

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche.

LPAR3 GFRA1

1.33e-041735225406395
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

RDX NCOR1 CDC42BPA NEB ECT2

1.33e-0449735523414517
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

PTBP1 SEPTIN5 SMC3 SEPTIN4

2.42e-0430435432235678
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

UTP23 FLII RDX PTBP1 SMC3 ECT2

3.35e-0494935636574265
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FLII RDX PRKCB NCOR1 SEPTIN5 ZBTB1

3.62e-0496335628671696
Pubmed

Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer.

FLII PTBP1

3.66e-042835224462114
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

SCYL1 FLII PTBP1 SMC3 CWF19L1

4.68e-0465335533742100
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

XRN1 FLII RDX PRKCB PTBP1 SEPTIN5 SEPTIN4

4.81e-04143135737142655
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

RDX PWWP3B CDC42BPA NEB GFRA1 CLIC3

4.81e-04101635619056867
Pubmed

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.

PRKCB SEPTIN5 SEPTIN4

6.25e-0416635327160897
Pubmed

Dynamic spatiotemporal gene expression in embryonic mouse thalamus.

BMP6 GFRA1

7.87e-044135221192082
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

XRN1 NCOR1 ZNF280D ZBTB1

8.02e-0441835434709266
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

PRKCB PWWP3B ECT2 SCN3A TBC1D14

8.03e-0473635529676528
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

XRN1 FLII PRKCB CDC42BPA PTBP1 SEPTIN5

8.76e-04113935636417873
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

XRN1 FLII PTBP1 SMC3 ECT2

9.22e-0475935535915203
GeneFamilySeptins

SEPTIN5 SEPTIN4

1.20e-0413232732
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZBTB37 ZNF81 ZBTB1 ZNF92

1.20e-0271823428
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB37 ZBTB1

1.25e-02134232861
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#1_top-relative-expression-ranked_200

LPAR3 GFRA1 SCN3A

1.17e-0527353DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k1_200
ToppCellLPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HS3ST5 PRKCB DENND5A ZNF280D

4.61e-06142354b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRKCB P2RX5 ZBTB1 SCN3A

1.20e-05181354d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCellASK452-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ZBTB37 ZNF280D ZNF92 CLIC3

1.52e-05192354f04ee5aaa54c39b7493098fb3d2f78168d6b8060
ToppCellsevere-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BMP6 P2RX5 ZNF92 SCN3A

1.58e-051943542fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

HS3ST5 BMP6 CLIC3

1.38e-04128353c09c50efff794848c5d64bdc469ce17a3e77a8a1
ToppCellHealthy-B_cell|Healthy / disease group, cell group and cell class

NEB P2RX5 SCN3A

2.33e-041533537f82cd61b3f1ebaee3e4bbf68ba858a67c2065e7
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCB LRRK1 ECT2

2.51e-04157353ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRKCB P2RX5 SCN3A

2.51e-04157353d12f343454202da86a06d0369f8ffe5662cd091b
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

ZNF81 NEB CLIC3

2.61e-0415935355e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LPAR3 BMP6 LRRK1

2.61e-0415935334c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRKCB BMP6 LRRK1

2.76e-041623538ed9149ff53b285591354057055d072b203a47c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRKCB BMP6 LRRK1

2.76e-041623537a05b05a33e1309fb5c0a8171db105ae68491815
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

XRN1 LRRK1 DENND5A

3.01e-04167353881f64db8dea3faa7588bf04d87c20924a4e5952
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCB SEPTIN5 ECT2

3.01e-04167353f5bffa77061baec0ba87bd688a047595f32534db
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP|Hippocampus / BrainAtlas - Mouse McCarroll V32

LPAR3 BMP6 LRRK1

3.07e-0416835326aa96b2b547d11941cb803995ea3d302ee0518c
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LPAR3 BMP6 LRRK1

3.23e-041713532e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCell3'_v3-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

PRKCB P2RX5 SCN3A

3.23e-041713539ecef653f6916572bf5fbee5aea6c577d04e96ba
ToppCellCOVID-19-kidney-Plasma|kidney / Disease (COVID-19 only), tissue and cell type

PRKCB BMP6 LRRK1

3.23e-04171353a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LPAR3 BMP6 LRRK1

3.23e-04171353e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRKCB BMP6 LRRK1

3.34e-0417335362ba49c1c16760a8c6cde0cc44e068f94386946a
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZBTB37 ALKAL1 ECT2

3.34e-0417335312c6875f881cb0fbff09d753b53c1cce7a95527f
ToppCell3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

ZNF81 ECT2 SCN3A

3.34e-0417335367f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCelldroplet-Fat-Scat-21m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC42BPA NEB SEPTIN4

3.34e-04173353f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PRKCB P2RX5 ZNF92

3.45e-04175353eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PRKCB P2RX5 ZNF92

3.45e-04175353ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

LPAR3 LRRK1 CLIC3

3.45e-0417535329fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

PRKCB BMP6 P2RX5

3.51e-041763539125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCellAdult-Immune-B_cell|Adult / Lineage, Cell type, age group and donor

PRKCB BMP6 LRRK1

3.51e-041763534aa00dcde907ad83d3aa4bb10439b7b5c4be1e5d
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HS3ST5 RDX CLIC3

3.57e-04177353b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

PRKCB P2RX5 SCN3A

3.57e-04177353653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LPAR3 BMP6 LRRK1

3.57e-04177353599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RX5 ZNF92 SCN3A

3.63e-041783535d41fede13c8e64b6fdaf2155f1eb72bcfc32fdb
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PWWP3B GFRA1 SCN3A

3.63e-0417835330ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP6 PWWP3B SCN3A

3.69e-041793537c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell3'_v3-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

PRKCB P2RX5 SCN3A

3.75e-04180353237a2130a3f48595dad2417539c21e44585962b8
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

BMP6 SEPTIN4 SCN3A

3.75e-041803537085a851807e6a833965e1366946db0bbc5174e2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRKCB BMP6 LRRK1

3.81e-041813535a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PWWP3B GFRA1 SCN3A

3.87e-04182353eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UTP23 P2RX5 CLIC3

3.87e-041823538ccffcbae28c374fd4161fb0d4cf2c49fae557f6
ToppCellIPF-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

PRKCB LPAR3 LRRK1

3.87e-041823530e8cfbd8ea196f27a227dbb4d2eb93bc48d27922
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

CDC42BPA SEPTIN4 SCN3A

3.94e-04183353273db6a3b00a93ca852498471187b642b5368185
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

BMP6 LRRK1 P2RX5

3.94e-041833532c016bb59f131a0e821853b085289a3583f0a729
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZBTB37 P2RX5 SEPTIN4

3.94e-04183353dc9602bed3136db91faeffef177006246dc92743
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRKCB LRRK1 P2RX5

4.00e-04184353942b58ae7172bb5f97e55b032db9329d161854af
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRKCB LRRK1 P2RX5

4.00e-04184353911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCellIPF-Myeloid-DC_Langerhans|IPF / Disease state, Lineage and Cell class

PRKCB LPAR3 LRRK1

4.06e-04185353f8ee3cb2aa9ec70f9ce8797be2b155da27ef6464
ToppCellIPF-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

PRKCB LPAR3 LRRK1

4.06e-04185353ced17f69486591c3cbbdc852a3e82c3f3a4a30d7
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP6 PWWP3B SCN3A

4.06e-041853532a8104f610fa5ce618f8105521616722462a0d42
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

RDX NCOR1 SMC3

4.06e-04185353857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

XRN1 BMP6 LRRK1

4.06e-041853533b77bc49cd3740acc025e162a36282ac09e12198
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRKCB P2RX5 ZBTB1

4.06e-04185353e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellIPF-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

BMP6 LRRK1 ECT2

4.13e-04186353f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

BMP6 LRRK1 SCN3A

4.13e-0418635366676d9395172de5707e204826a1c9f73b448cca
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

C12orf56 SEPTIN4 GFRA1

4.19e-04187353f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

C12orf56 SEPTIN4 GFRA1

4.19e-0418735302e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

C12orf56 SEPTIN4 GFRA1

4.19e-0418735308c73d125e0638c9e9878165bba2442c266c8a48
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PWWP3B GFRA1 SCN3A

4.26e-04188353e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPAR3 GFRA1 CLIC3

4.26e-04188353a6cbe58c5029acefbfbb64c3bff570de4e5e2449
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPAR3 GFRA1 CLIC3

4.26e-041883536fb37e3b139955e6ee6be26ab6cd3ce85d765ca6
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRKCB LRRK1 P2RX5

4.26e-041883539a10536afa2dea34c78421d36564cfd8252afe45
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDX NCOR1 SMC3

4.26e-04188353d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRKCB BMP6 LRRK1

4.26e-04188353567b08514d9d84cbb40f9b7a679eec304f023428
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ZBTB37 PRKCB SEPTIN4

4.33e-04189353f4865b7db16de15120504147a8016ac522ad242a
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRKCB P2RX5 SCN3A

4.39e-04190353a7498fe55b7810c482291db782dc5282675d246a
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

P2RX5 ZNF92 SCN3A

4.39e-04190353e63945fa1dcd58bee129f1dd0c23b64a76241554
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

P2RX5 ZNF92 SCN3A

4.39e-04190353fa65bc5a178ae0c80a9bd4b282e4539493128a64
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RX5 ZNF92 SCN3A

4.46e-041913532feab42ac6d29fa4eac78f3f78a5f8aa0a559523
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

P2RX5 ZNF92 SCN3A

4.46e-041913538dda37ebf74b587129795f61541cc511ec97a314
ToppCell18-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

NCOR1 BMP6 ALKAL1

4.46e-0419135386ce98d2c90c196474b06869de888cf5d1eed196
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

PRKCB LRRK1 TBC1D14

4.46e-04191353cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RX5 ZNF92 SCN3A

4.60e-04193353cf4ba50aa4a00d1ba22fc7626d49a4104377d5d9
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

HS3ST5 BMP6 PWWP3B

4.60e-041933532bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCB SMC3 GFRA1

4.67e-041943538ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellmedial-2-Hematologic-EREG+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRKCB NEB TBC1D14

4.67e-04194353b2b4e4c3ac0df0d9f17b930ffb60c0fd85b3dd78
ToppCellCOVID-19_Moderate-B_naive|World / disease group, cell group and cell class

P2RX5 ZNF92 SCN3A

4.67e-041943531f81d618799e482a36dce528bba70f52cc69a901
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRKCB LRRK1 P2RX5

4.67e-04194353ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellCOVID-19_Severe-B_naive|World / disease group, cell group and cell class

P2RX5 ZNF92 SCN3A

4.67e-04194353d363963a6caeedf4f9e9ad22dcf9b66b85c79a48
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

HS3ST5 RDX CDC42BPA

4.67e-0419435388db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCellmedial-Hematologic-EREG+_Dendritic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRKCB NEB TBC1D14

4.67e-041943531f3d22292d2691f93aa7b6770f5c250a33db3cc0
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

HS3ST5 RDX CDC42BPA

4.67e-04194353a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellCOVID-19_Moderate-B_naive|COVID-19_Moderate / disease group, cell group and cell class

P2RX5 ZNF92 SCN3A

4.67e-041943538c41a37467bfd4966ecd09dde68c543dc01b6ad0
ToppCellmedial-Hematologic-EREG+_Dendritic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRKCB NEB TBC1D14

4.67e-0419435315f3b6b6579e388d0820f05e93a77ee1634bd6c3
ToppCellLung_Parenchyma-Control-Lymphocyte-B|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRKCB P2RX5 SCN3A

4.74e-04195353c5ed36f649dc43c2811637890bbc5192981c7311
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

XRN1 NCOR1 ZNF81

4.74e-0419535383c125223e7ca0f08a31414b3a16347912564765
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|tumor_Lung / Location, Cell class and cell subclass

ALKAL1 SEPTIN4 GFRA1

4.74e-04195353ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 PRKCB NCOR1

4.74e-041953537796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellsevere-B_cell|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BMP6 P2RX5 SCN3A

4.74e-041953530fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCellCOVID-19_Severe-PLT_4|World / Disease Group and Platelet Clusters

ZNF280D SMC3 ZBTB1

4.81e-04196353ad43efdd4d73b6615f65f06a315b33576e317473
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-B-B_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRKCB P2RX5 ZNF92

4.81e-04196353f37ffb916480281e5905733ac304102dd2e0c05f
ToppCellLung_Parenchyma-Control-Lymphocyte-B-B_cell-B_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRKCB P2RX5 SCN3A

4.81e-04196353279f113916dcb398111d787ae06bcf20ff8febd2
ToppCellParenchyma_Control_(B.)-Immune-TX-B_cells|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PRKCB P2RX5 SCN3A

4.81e-04196353a2759691606b03de9d67e8d38487915cd4e7d448
ToppCellLung_Parenchyma-Control-Lymphocyte-B-B_cell-B_cell-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRKCB P2RX5 SCN3A

4.81e-04196353b4e815f198eac3256302488750e352b436d632f0
ToppCellNasal_Brush-Epithelial-Goblet_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CYP2A13 CDC42BPA CLIC3

4.81e-04196353e16f0831f1f677b28e4a8014f0aede7e713d4f04
ToppCellLung_Parenchyma-Control-Lymphocyte-B-B_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRKCB P2RX5 SCN3A

4.81e-0419635304a09f99c59b1ae8f72d85505b88f88cbe748260
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-Memory_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

PRKCB LRRK1 P2RX5

4.81e-04196353c450cd6b799932f5cce8326d1079114abeb71e95
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-B-B_cell-B_mature|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRKCB P2RX5 ZNF92

4.81e-041963534b9eb163b9dbbf5eebb160f6554f6f28cb234d31
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRKCB BMP6 LRRK1

4.81e-04196353fc67d8aad1ec4d7f98ffe44fb103e230b9b42c35
ToppCellNasal_Brush-Epithelial-Goblet_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CYP2A13 CDC42BPA CLIC3

4.81e-0419635371e88d9ca28168732bd91f2d4f8f53bb4187963a
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRKCB BMP6 LRRK1

4.88e-041973530f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

LRRK1 DENND5A NEB

4.88e-0419735315b87fd3906d7388c271d30d0c64b1bcc490801c
Diseaseanxiety disorder (implicated_via_orthology)

NCOR1 SCN3A

3.11e-0422352DOID:2030 (implicated_via_orthology)
DiseaseAdult T-Cell Lymphoma/Leukemia

PRKCB BMP6

6.22e-0431352C0023493
DiseaseAtaxia, Spinocerebellar

SCYL1 CWF19L1

7.49e-0434352C0087012
DiseaseSpinocerebellar Ataxia Type 2

SCYL1 CWF19L1

7.49e-0434352C0752121
DiseaseSpinocerebellar Ataxia Type 1

SCYL1 CWF19L1

7.49e-0434352C0752120
DiseaseSpinocerebellar Ataxia Type 5

SCYL1 CWF19L1

7.49e-0434352C0752123
DiseaseSpinocerebellar Ataxia Type 7

SCYL1 CWF19L1

7.49e-0434352C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

SCYL1 CWF19L1

7.49e-0434352C0752124
DiseaseSpinocerebellar Ataxia Type 4

SCYL1 CWF19L1

7.94e-0435352C0752122
Diseaseantibody measurement

RDX C12orf56

1.55e-0349352EFO_0004556
Diseasepsoriasis, type 2 diabetes mellitus

RDX CWF19L1

3.59e-0375352EFO_0000676, MONDO_0005148
Diseasethyroxine measurement

NCOR1 PWWP3B

4.38e-0383352EFO_0005130
Diseaseneutrophil percentage of leukocytes

CDC42BPA ZBTB1 ZNF92 TBC1D14

5.70e-03610354EFO_0007990
Diseasebrain ischemia (biomarker_via_orthology)

BMP6 GFRA1

6.54e-03102352DOID:2316 (biomarker_via_orthology)
Diseaselymphocyte percentage of leukocytes

LRRK1 PTBP1 ZNF92 TBC1D14

7.69e-03665354EFO_0007993
DiseaseGlioblastoma Multiforme

PRKCB NCOR1

7.70e-03111352C1621958
Diseaseimmature platelet fraction

SEPTIN5 TBC1D14

8.10e-03114352EFO_0009187

Protein segments in the cluster

PeptideGeneStartEntry
NASPFRKHFKKFALS

nan

246

A8MVM7
FHSNRPSKRFCIFKK

ZNF280D

666

Q6N043
NDVFHKFSAFIKNPV

CLIC3

106

O95833
FPRDSNLKDKFIKHF

ALKAL1

66

Q6UXT8
EKRLAAQFIPKFFKH

API5

41

Q9BZZ5
KQKPRFHAFLKINQA

ECT2

566

Q9H8V3
KKENPLQFKFRAKFF

RDX

71

P35241
ENPKFLSHFKRKFII

FLII

1026

Q13045
PVAVKRFHIKKFKNF

LRRK1

1266

Q38SD2
RFHIKKFKNFANVPA

LRRK1

1271

Q38SD2
KLFHRIKKNFPLQFG

CWF19L1

476

Q69YN2
ITKLRKFFHPFNQKF

HS3ST5

321

Q8IZT8
VIAAVIKNRKFHFPF

LPAR3

51

Q9UBY5
NHKFTARFFKQPTFC

PRKCB

36

P05771
FNPQHFLDKKGQFKK

CYP2A13

411

Q16696
KCHKALRQFFDKVPA

GFRA1

191

P56159
KEFSPRQRHHKEFKF

BMP6

226

P22004
FQHGFKSPRLFKNVF

DENND5A

1151

Q6IQ26
FIKNHIRFPKFNFSK

P2RX5

191

Q93086
QKHAKKHLGFFRNNF

UTP23

6

Q9BRU9
NPRFDKAFKHVFGKT

SMC3

616

Q9UQE7
PNQVHRKSVKKGFDF

SEPTIN4

131

O43236
PNQVHRKSVKKGFDF

SEPTIN5

31

Q99719
AKAAFKRFKTLRHPN

SCYL1

61

Q96KG9
KQDTFRNKFPKLHNE

PWWP3B

506

Q5H9M0
EIFKDKFIQHPKNFG

NCOR1

446

O75376
FQKAFFRKPKVIEIH

SCN3A

1026

Q9NY46
FPPKRKTHQFFVKSF

CDC42BPA

1006

Q5VT25
KPNKQAEKRFKNFLH

C12orf29

81

Q8N999
AEKRFKNFLHSKENP

C12orf29

86

Q8N999
CKKSNSVRKFLFPFH

C12orf56

116

Q8IXR9
FEENLPKLFAHFKKN

TBC1D14

561

Q9P2M4
VKVFHKFPNVNRNKI

ZNF92

151

Q03936
KSFPFQAILNQHFRK

ZBTB37

436

Q5TC79
RHKFFLKKSGVQVFQ

XRN1

666

Q8IZH2
IQKKQLFKHSACPFR

ZBTB1

521

Q9Y2K1
HRFKKPGSKNFQNIF

PTBP1

436

P26599
KIFTQRSHFFAPQKI

ZNF81

281

P51508
DQKYRQHPSNFQFKK

NEB

2201

P20929