Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	mRNA processing	PCF11 SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SRRM4 SCAF11 SRRM2 RBM20 NCBP3	1.30e-07	551	65	12	GO:0006397
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 SCAF11 SRRM2 RBM20	1.76e-06	358	65	9	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 SCAF11 SRRM2 RBM20	1.76e-06	358	65	9	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 SCAF11 SRRM2 RBM20	1.92e-06	362	65	9	GO:0000375
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 RBM20	3.25e-06	129	65	6	GO:0048024
GeneOntologyBiologicalProcess	RNA splicing	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SRRM4 SCAF11 SRRM2 RBM20	3.60e-06	502	65	10	GO:0008380
GeneOntologyBiologicalProcess	mRNA metabolic process	PCF11 SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SRRM4 LARP1 SCAF11 SRRM2 RBM20 NCBP3	4.67e-06	917	65	13	GO:0016071
GeneOntologyBiologicalProcess	regulation of mRNA processing	SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 RBM20	1.04e-05	158	65	6	GO:0050684
GeneOntologyBiologicalProcess	regulation of alternative mRNA splicing, via spliceosome	SRSF2 SRSF6 SRRM4 RBM20	3.59e-05	59	65	4	GO:0000381
GeneOntologyBiologicalProcess	regulation of RNA splicing	SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 RBM20	4.79e-05	207	65	6	GO:0043484
GeneOntologyBiologicalProcess	negative regulation of mRNA splicing, via spliceosome	SRSF6 SRSF7 RBM20	9.25e-05	28	65	3	GO:0048025
GeneOntologyBiologicalProcess	negative regulation of mRNA processing	SRSF6 SRSF7 RBM20	1.03e-04	29	65	3	GO:0050686
GeneOntologyBiologicalProcess	alternative mRNA splicing, via spliceosome	SRSF2 SRSF6 SRRM4 RBM20	1.13e-04	79	65	4	GO:0000380
GeneOntologyBiologicalProcess	negative regulation of RNA splicing	SRSF6 SRSF7 RBM20	1.52e-04	33	65	3	GO:0033119
GeneOntologyBiologicalProcess	negative regulation of mRNA metabolic process	SRSF6 SRSF7 LARP1 RBM20	4.78e-04	115	65	4	GO:1903312
GeneOntologyBiologicalProcess	regulation of mRNA metabolic process	SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 LARP1 RBM20	4.78e-04	443	65	7	GO:1903311
GeneOntologyCellularComponent	nuclear speck	SRRM1 SRSF2 HDAC5 SRSF6 SRSF7 ZC3H13 RREB1 SRRM2 NCBP3	6.25e-06	431	64	9	GO:0016607
GeneOntologyCellularComponent	nuclear body	SRRM1 SRSF2 HDAC5 SRSF6 SRSF7 ZC3H13 SCAF11 RREB1 SRRM2 NCBP3	3.92e-04	903	64	10	GO:0016604
MousePheno	absent vestibular hair cell stereocilia	SRRM4 KCNQ1	4.22e-05	3	53	2	MP:0004518
Domain	BAH	ORC1 DNMT1	6.04e-04	11	63	2	SM00439
Domain	BAH	ORC1 DNMT1	6.04e-04	11	63	2	PF01426
Domain	BAH	ORC1 DNMT1	6.04e-04	11	63	2	PS51038
Domain	BAH_dom	ORC1 DNMT1	6.04e-04	11	63	2	IPR001025
Domain	TIL	VWF MUC5AC	7.23e-04	12	63	2	PF01826
Domain	C8	VWF MUC5AC	7.23e-04	12	63	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF MUC5AC	8.53e-04	13	63	2	IPR014853
Domain	C8	VWF MUC5AC	8.53e-04	13	63	2	SM00832
Domain	TIL_dom	VWF MUC5AC	9.93e-04	14	63	2	IPR002919
Domain	VWD	VWF MUC5AC	1.30e-03	16	63	2	SM00216
Domain	VWF_type-D	VWF MUC5AC	1.30e-03	16	63	2	IPR001846
Domain	VWFD	VWF MUC5AC	1.30e-03	16	63	2	PS51233
Domain	VWD	VWF MUC5AC	1.30e-03	16	63	2	PF00094
Domain	-	SRSF2 SRSF6 SRSF7 RBM20 NCBP3	1.39e-03	244	63	5	3.30.70.330
Domain	CTCK_1	VWF MUC5AC	1.65e-03	18	63	2	PS01185
Domain	Nucleotide-bd_a/b_plait	SRSF2 SRSF6 SRSF7 RBM20 NCBP3	1.77e-03	258	63	5	IPR012677
Domain	VWC_out	VWF MUC5AC	1.85e-03	19	63	2	SM00215
Domain	RasGEFN	RASGRF1 KNDC1	2.05e-03	20	63	2	SM00229
Domain	RasGEF_N	RASGRF1 KNDC1	2.26e-03	21	63	2	PF00618
Domain	SH3_9	SH3KBP1 MAP3K9 SORBS1	2.32e-03	78	63	3	PF14604
Domain	Ras-like_Gua-exchang_fac_N	RASGRF1 KNDC1	2.48e-03	22	63	2	IPR000651
Domain	RASGEF_NTER	RASGRF1 KNDC1	2.48e-03	22	63	2	PS50212
Domain	CT	VWF MUC5AC	2.48e-03	22	63	2	SM00041
Domain	VWFA	VWF ITGAE ITGB7	2.68e-03	82	63	3	PS50234
Domain	VWA	VWF ITGAE ITGB7	2.87e-03	84	63	3	SM00327
Domain	SH3_2	SH3KBP1 MAP3K9 SORBS1	3.07e-03	86	63	3	IPR011511
Domain	SH3_2	SH3KBP1 MAP3K9 SORBS1	3.07e-03	86	63	3	PF07653
Domain	Integrin_dom	ITGAE ITGB7	3.20e-03	25	63	2	IPR032695
Domain	Cys_knot_C	VWF MUC5AC	3.20e-03	25	63	2	IPR006207
Domain	CTCK_2	VWF MUC5AC	3.20e-03	25	63	2	PS01225
Domain	RASGEF	RASGRF1 KNDC1	3.45e-03	26	63	2	PS00720
Domain	VWC	VWF MUC5AC	4.00e-03	28	63	2	PF00093
Domain	RASGEF_CAT	RASGRF1 KNDC1	4.29e-03	29	63	2	PS50009
Domain	VWF_A	VWF ITGAE ITGB7	4.56e-03	99	63	3	IPR002035
Domain	RasGEF	RASGRF1 KNDC1	4.58e-03	30	63	2	PF00617
Domain	-	RASGRF1 KNDC1	4.58e-03	30	63	2	1.10.840.10
Domain	Ras_GEF_dom	RASGRF1 KNDC1	4.58e-03	30	63	2	IPR023578
Domain	RASGEF_cat_dom	RASGRF1 KNDC1	4.58e-03	30	63	2	IPR001895
Domain	RasGEF	RASGRF1 KNDC1	4.58e-03	30	63	2	SM00147
Domain	RRM	SRSF2 SRSF6 SRSF7 RBM20	6.18e-03	217	63	4	SM00360
Domain	VWFC_1	VWF MUC5AC	6.55e-03	36	63	2	PS01208
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION	PCF11 SRRM1 SRSF2 SRSF6 SRSF7	3.38e-06	67	49	5	M27694
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	PCF11 SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 SRRM2	5.09e-05	283	49	7	M13087
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION	PCF11 SRRM1 SRSF2 SRSF7	6.20e-05	62	49	4	MM15426
Pathway	REACTOME_MRNA_SPLICING	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 SRRM2	8.79e-05	212	49	6	M14033
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	SRRM1 SRSF2 SRSF6 SRSF7	2.03e-04	84	49	4	M725
Pathway	WP_RETINOBLASTOMA_GENE_IN_CANCER	ORC1 ANLN CCDC6 DNMT1	2.64e-04	90	49	4	M39678
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	PCF11 SNRNP27 SRRM1 SRSF2 SRSF7 SRRM2	3.75e-04	277	49	6	MM15414
Pathway	REACTOME_MRNA_SPLICING	SNRNP27 SRRM1 SRSF2 SRSF7 SRRM2	6.42e-04	201	49	5	MM15411
Pathway	REACTOME_MRNA_SPLICING_MINOR_PATHWAY	SRSF2 SRSF6 SRSF7	6.90e-04	50	49	3	M5583
Pathway	WP_MRNA_PROCESSING	SRRM1 SRSF2 SRSF6 SRSF7	9.45e-04	126	49	4	M39406
Pathway	KEGG_SPLICEOSOME	SNRNP27 SRSF2 SRSF6 SRSF7	9.73e-04	127	49	4	M2044
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PCF11 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ANLN ZC3H13 BAG3 AAK1 LARP1 SCAF11 CCDC6 RREB1 SRRM2 DNMT1	1.21e-12	774	67	16	15302935
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SRRM1 PANK2 ANLN BAG3 AAK1 MEPCE MAP3K9 LARP1 FAM117B SORBS1 CCDC6 CDK14 SRRM2 MAP3K6 DNMT1	7.45e-11	861	67	15	36931259
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	SRRM1 SRSF2 GTF3C1 NFATC2IP ANLN ZC3H13 BAG3 AAK1 LARP1 PLEKHA6 CCDC6 SRRM2	2.14e-10	503	67	12	16964243
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PCF11 SRRM1 SYCP2 SRSF6 SRSF7 RASGRF1 ZC3H13 UBR4 BAG3 SRRM2	1.88e-09	361	67	10	26167880
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NRXN2 JADE2 SRRM4 AAK1 LARP1 SCAF11 HHIPL1 CDK14 RIMS2 KIAA1614 ACAP3	5.42e-09	529	67	11	14621295
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PCF11 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 JADE2 ZC3H13 SENP3 MEPCE LARP1 SCAF11 SRRM2	7.30e-09	847	67	13	35850772
Pubmed	Lysine acetylation targets protein complexes and co-regulates major cellular functions.	SRSF2 SRSF6 SRSF7 LARP1 SRRM2	1.09e-08	38	67	5	19608861
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	SRRM1 SGIP1 RASGRF1 SH3KBP1 AAK1 SORBS1 PLEKHA6 RIMS2 SRRM2	2.27e-08	347	67	9	17114649
Pubmed	The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes.	SRRM1 SRSF2 SRRM2	2.73e-08	4	67	3	10908574
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PCF11 SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 LARP1 SCAF11 RREB1 SRRM2 DNMT1 NCBP3	2.96e-08	954	67	13	36373674
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 LARP1 CCDC6 SRRM2	3.19e-08	361	67	9	30344098
Pubmed	Recruitment of the human TREX complex to mRNA during splicing.	SRRM1 SRSF2 SRSF7 ZC3H13	5.95e-08	20	67	4	15998806
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	SRRM1 SRSF7 ANLN SH3KBP1 SRRM2 DNMT1	6.67e-08	108	67	6	19531213
Pubmed	The protein interaction landscape of the human CMGC kinase group.	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 MEPCE LARP1 FAM117B CDK14 SRRM2 NCBP3	8.73e-08	695	67	11	23602568
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	GTF3C1 NFATC2IP ANLN UBR4 SCAF11 RREB1 SRRM2 DNMT1	2.53e-07	332	67	8	32786267
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 MEPCE LARP1 SCAF11 SRRM2 PURG NCBP3	3.86e-07	807	67	11	22681889
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 LARP1 SRRM2	4.06e-07	239	67	7	26641092
Pubmed	The SR protein family.	SRSF2 SRSF6 SRSF7	5.69e-07	9	67	3	19857271
Pubmed	A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.	SGIP1 SRRM4 SORBS1 PLEKHA6 RIMS2	6.64e-07	85	67	5	23055939
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SRRM1 SRSF2 ZC3H13 LARP1 CCDC6 SRRM2	7.61e-07	163	67	6	22113938
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SRRM2	9.40e-07	169	67	6	23084401
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ORC1 SNRNP27 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ZC3H13 SENP3 SCAF11 RREB1 SRRM2 DNMT1	9.65e-07	1294	67	13	30804502
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	PCF11 SRRM1 SRSF2 SRSF6 SRSF7 SRRM2	9.73e-07	170	67	6	16159877
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	PCF11 SRRM1 SRSF2 SRSF6 ZC3H13 BAG3 LARP1 SRRM2	1.01e-06	399	67	8	35987950
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ZC3H13 MEPCE LARP1 SRRM2 NCBP3	1.07e-06	713	67	10	29802200
Pubmed	SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells.	SRRM1 SRSF2 SRSF6	1.12e-06	11	67	3	9472028
Pubmed	A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).	SRSF2 SRSF6 SRSF7	1.93e-06	13	67	3	20516191
Pubmed	Comprehensive proteomic analysis of the human spliceosome.	PCF11 SRRM1 SRSF2 SRSF6 SRSF7	2.28e-06	109	67	5	12226669
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	ORC1 SRSF2 SRSF6 GTF3C1 SRSF7 ANLN BAG3 MEPCE SCAF11 SRRM2 DNMT1	2.79e-06	989	67	11	36424410
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	SRRM1 SRSF2 SRSF6 SRSF7 SRRM2	2.97e-06	115	67	5	17332742
Pubmed	Relative strength of 5' splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA.	SRSF2 SRSF6	3.66e-06	2	67	2	33050987
Pubmed	Alpha E beta 7 (CD103) expression identifies a highly active, tonsil-resident effector-memory CTL population.	ITGAE ITGB7	3.66e-06	2	67	2	16177076
Pubmed	Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells.	ITGAE ITGB7	3.66e-06	2	67	2	12242333
Pubmed	The SRm160/300 splicing coactivator subunits.	SRRM1 SRRM2	3.66e-06	2	67	2	10668804
Pubmed	Cryo-EM structure of I domain-containing integrin αEβ7.	ITGAE ITGB7	3.66e-06	2	67	2	38781659
Pubmed	β7 Integrin controls mast cell recruitment, whereas αE integrin modulates the number and function of CD8+ T cells in immune complex-mediated tissue injury.	ITGAE ITGB7	3.66e-06	2	67	2	24670804
Pubmed	Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution.	ITGAE ITGB7	3.66e-06	2	67	2	8119947
Pubmed	Balanced splicing at the Tat-specific HIV-1 3'ss A3 is critical for HIV-1 replication.	SRSF2 SRSF6	3.66e-06	2	67	2	25889056
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	SRSF2 SRSF6 SRSF7 MEPCE LARP1 CCDC6 SRRM2 DNMT1 NCBP3	4.45e-06	653	67	9	33742100
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SRRM1 SRSF2 GTF3C1 ZC3H13 UBR4 LARP1 SCAF11 SRRM2 DNMT1	4.45e-06	653	67	9	22586326
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 MEPCE LARP1 SCAF11 SRRM2	5.47e-06	670	67	9	22990118
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	SGIP1 SORBS1 PLEKHA6 RIMS2 SRRM2 PURG	5.72e-06	231	67	6	16452087
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	SRRM1 ZC3H13 SH3KBP1 CCDC6 SRRM2	6.05e-06	133	67	5	15144186
Pubmed	Splicing factor TRA2B is required for neural progenitor survival.	SRSF6 SRSF7 SCAF11	6.48e-06	19	67	3	23818142
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SENP3 UBR4 MEPCE LARP1 RREB1 SRRM2 DNMT1	7.28e-06	1318	67	12	30463901
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	ORC1 SRRM1 GTF3C1 SENP3 AAK1 SCAF11 NCBP3	7.32e-06	370	67	7	22922362
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	SRSF6 GTF3C1 SRSF7 MEPCE LARP1 SCAF11	7.82e-06	244	67	6	29884807
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SH3KBP1 LARP1 CCDC6 SRRM2 DNMT1	1.03e-05	922	67	10	27609421
Pubmed	Role for E-cadherin as an inhibitory receptor on epidermal gammadelta T cells.	ITGAE ITGB7	1.10e-05	3	67	2	21562159
Pubmed	The role of alpha and beta chains in ligand recognition by beta 7 integrins.	ITGAE ITGB7	1.10e-05	3	67	2	10837471
Pubmed	Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis.	ITGAE ITGB7	1.10e-05	3	67	2	17325197
Pubmed	Molecular basis for leukocyte integrin alpha(E)beta(7) adhesion to epithelial (E)-cadherin.	ITGAE ITGB7	1.10e-05	3	67	2	10790430
Pubmed	Identification of ITGA4/ITGB7 and ITGAE/ITGB7 expressing subsets of decidual dendritic-like cells within distinct microdomains of the pregnant mouse uterus.	ITGAE ITGB7	1.10e-05	3	67	2	18562709
Pubmed	Dual effect of the SR proteins ASF/SF2, SC35 and 9G8 on HIV-1 RNA splicing and virion production.	SRSF2 SRSF7	1.10e-05	3	67	2	15907217
Pubmed	Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development.	KCNQ1 DNMT1	1.10e-05	3	67	2	26241757
Pubmed	Blockade of αEβ7 integrin suppresses accumulation of CD8+ and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo.	ITGAE ITGB7	1.10e-05	3	67	2	27543429
Pubmed	Epigenetic modification of intestinal smooth muscle cell phenotype during proliferation.	HDAC5 DNMT1	1.10e-05	3	67	2	30110565
Pubmed	A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.	SRSF2 SRSF7 SENP3 SORBS1	1.24e-05	73	67	4	22094256
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	PCF11 SRRM1 SRSF2 SRSF6 SRSF7 ANLN SENP3 SRRM2	1.61e-05	582	67	8	20467437
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SNRNP27 HDAC5 GTF3C1 UBR4 BAG3 RREB1 RBM20	1.61e-05	418	67	7	34709266
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	SRRM1 SRSF2 GTF3C1 SRSF7 UBR4 LARP1 SCAF11 DNMT1	2.02e-05	601	67	8	33658012
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	SRRM1 SRSF6 SRSF7 ZC3H13 LARP1 SCAF11 SRRM2 NCBP3	2.12e-05	605	67	8	28977666
Pubmed	A family of beta 7 integrins on human mucosal lymphocytes.	ITGAE ITGB7	2.19e-05	4	67	2	1542691
Pubmed	STAT3-mediated epigenetic silencing of FOXP3 in LADA T cells is regulated through HDAC5 and DNMT1.	HDAC5 DNMT1	2.19e-05	4	67	2	29223407
Pubmed	Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta.	ITGAE ITGB7	2.19e-05	4	67	2	11934870
Pubmed	Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins.	SRSF2 SRSF7	2.19e-05	4	67	2	15184380
Pubmed	The alpha 1 beta 1 and alpha E beta 7 integrins define a subset of dendritic cells in peripheral lymph nodes with unique adhesive and antigen uptake properties.	ITGAE ITGB7	2.19e-05	4	67	2	14688336
Pubmed	Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogen.	ITGAE ITGB7	2.19e-05	4	67	2	14688352
Pubmed	Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA.	SRSF2 SRSF7	2.19e-05	4	67	2	15123677
Pubmed	Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions.	SRRM1 SRSF6	2.19e-05	4	67	2	10809668
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SRRM1 GTF3C1 NFATC2IP ANLN SCAF11 RREB1 DNMT1 NCBP3	2.19e-05	608	67	8	36089195
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	HROB SRSF2 HDAC5 SRSF6 SRSF7 AAK1 KNDC1 PLEKHA6 CCDC6 ACAP3	2.85e-05	1038	67	10	26673895
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	SRRM1 PANK2 SRSF2 SRSF6 SRSF7 UBR4 LARP1 SORBS1 CCDC6 CDK14 SRRM2	3.21e-05	1284	67	11	17353931
Pubmed	Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.	SRSF6 SRSF7 LARP1 SRRM2 NCBP3	3.22e-05	188	67	5	29721183
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	PANK2 HDAC5 ZC3H13 LARP1 DNMT1	3.39e-05	190	67	5	15161933
Pubmed	Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease.	ITGAE ITGB7	3.64e-05	5	67	2	34467254
Pubmed	Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis.	VWF CNMD	3.64e-05	5	67	2	16980969
Pubmed	Identification and characterization of a novel serine-arginine-rich splicing regulatory protein.	SRSF2 SRSF6	3.64e-05	5	67	2	10757789
Pubmed	A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis.	ITGAE ITGB7	3.64e-05	5	67	2	18250468
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	SRRM1 SRSF6 GTF3C1 SRSF7 BAG3 MEPCE LARP1 SRRM2	3.72e-05	655	67	8	35819319
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	SNRNP27 SRSF2 SRSF6 SRRM2 NCBP3	4.03e-05	197	67	5	22365833
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PCF11 SNRNP27 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 NRXN2 ZC3H13 SRRM2	4.04e-05	1082	67	10	38697112
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	SRRM1 SRSF2 SRSF7 UBR4 BAG3 LARP1 SRRM2 DNMT1	4.14e-05	665	67	8	30457570
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	PANK2 HDAC5 SRSF6 SRSF7 BAG3 AAK1 LARP1 PCARE FAM117B RREB1 MUC5AC	4.15e-05	1321	67	11	27173435
Pubmed	A coactivator of pre-mRNA splicing.	SRRM1 SRRM2	5.46e-05	6	67	2	9531537
Pubmed	SR proteins: a conserved family of pre-mRNA splicing factors.	SRSF2 SRSF6	5.46e-05	6	67	2	1577277
Pubmed	HIV-1 transcription is regulated by splicing factor SRSF1.	SRSF2 SRSF7	5.46e-05	6	67	2	25416801
Pubmed	Genetic basis of dilated cardiomyopathy.	BAG3 KCNQ1	5.46e-05	6	67	2	27736720
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	PCF11 SNRNP27 SRRM1 SRSF2 SRSF7 AAK1 LARP1 SCAF11 MUC5AC DNMT1 NCBP3	5.80e-05	1371	67	11	36244648
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	VWF ANLN AAK1 LARP1 CCDC6 SRRM2	6.92e-05	360	67	6	33111431
Pubmed	The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins.	ITGAE ITGB7	7.63e-05	7	67	2	9765275
Pubmed	Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression.	SRSF2 SRSF7	7.63e-05	7	67	2	32338600
Pubmed	Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.	SRSF2 SCAF11	7.63e-05	7	67	2	9447963
Pubmed	A serine kinase regulates intracellular localization of splicing factors in the cell cycle.	SRSF6 SCAF11	7.63e-05	7	67	2	8208298
Pubmed	Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing.	ITGAE ITGB7	7.63e-05	7	67	2	11696590
Pubmed	Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.	ITGAE ITGB7	7.63e-05	7	67	2	30700910
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	PANK2 SH3KBP1 AAK1 LARP1 SORBS1	7.71e-05	226	67	5	31452512
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 LARP1 SRRM2	8.02e-05	731	67	8	29298432
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAM47A GTF3C1 ZC3H13 UBR4 MAP3K9 LARP1 PCARE ITGAE	8.40e-05	736	67	8	29676528
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	VWF SGIP1 SRSF2 SRSF7 NRXN2 SH3KBP1 AAK1 KNDC1 LARP1 SORBS1 PLEKHA6	8.50e-05	1431	67	11	37142655
Interaction	SRPK2 interactions	PCF11 SNRNP27 SRRM1 SYCP2 SRSF2 SRSF6 SRSF7 RASGRF1 ANLN ZC3H13 UBR4 BAG3 SCAF11 SRRM2 PURG NCBP3	7.12e-10	717	65	16	int:SRPK2
Interaction	YWHAE interactions	PANK2 SRSF2 HDAC5 SRSF6 SRSF7 RASGRF1 ANLN BAG3 AAK1 MEPCE MAP3K9 LARP1 SCAF11 FAM117B SORBS1 CCDC6 CDK14 RIMS2 SRRM2 DNMT1	1.28e-09	1256	65	20	int:YWHAE
Interaction	CLK3 interactions	SRRM1 SRSF6 SRSF7 ANLN ZC3H13 SH3KBP1 MEPCE LARP1 SRRM2 PURG	2.08e-09	220	65	10	int:CLK3
Interaction	SRSF4 interactions	SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 UBR4 MEPCE LARP1 SCAF11 SRRM2 NCBP3	2.90e-09	300	65	11	int:SRSF4
Interaction	YWHAH interactions	SRRM1 PANK2 HDAC5 ANLN ZC3H13 BAG3 AAK1 MEPCE MAP3K9 LARP1 FAM117B SORBS1 CCDC6 CDK14 RIMS2 SRRM2 MAP3K6 DNMT1	7.17e-09	1102	65	18	int:YWHAH
Interaction	CLK2 interactions	SNRNP27 SRRM1 SRSF6 SRSF7 MEPCE LARP1 SRRM2 PURG NCBP3	1.24e-08	195	65	9	int:CLK2
Interaction	DHX8 interactions	PCF11 SRRM1 SRSF6 SRSF7 ANLN ZC3H13 BAG3 SCAF11 SRRM2 PURG	3.10e-08	292	65	10	int:DHX8
Interaction	YWHAG interactions	SRRM1 PANK2 HDAC5 ANLN ZC3H13 BAG3 AAK1 MEPCE MAP3K9 LARP1 SCAF11 FAM117B SORBS1 CCDC6 CDK14 SRRM2 MAP3K6 DNMT1	4.88e-08	1248	65	18	int:YWHAG
Interaction	SRSF7 interactions	SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ANLN SH3KBP1 MEPCE LARP1 SRRM2 NCBP3	1.04e-07	425	65	11	int:SRSF7
Interaction	MEN1 interactions	PCF11 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 JADE2 ANLN ZC3H13 SENP3 UBR4 MEPCE LARP1 SCAF11 SRRM2 NCBP3	1.16e-07	1029	65	16	int:MEN1
Interaction	SRRM1 interactions	PCF11 SRRM1 SRSF2 SRSF6 SRSF7 ANLN SRRM4 SH3KBP1 SRRM2 PURG	1.60e-07	348	65	10	int:SRRM1
Interaction	SRSF5 interactions	SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ANLN MEPCE LARP1 SCAF11 SRRM2 PURG	3.09e-07	474	65	11	int:SRSF5
Interaction	CLK1 interactions	SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SRRM4 BAG3 SRRM2	5.07e-07	219	65	8	int:CLK1
Interaction	SRSF6 interactions	SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 MEPCE LARP1 SCAF11 SRRM2 NCBP3	5.56e-07	503	65	11	int:SRSF6
Interaction	SRSF3 interactions	SRRM1 SRSF2 SRSF6 SRSF7 ANLN MEPCE LARP1 SCAF11 CCDC6 SRRM2 NCBP3	8.01e-07	522	65	11	int:SRSF3
Interaction	BARD1 interactions	SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 MEPCE LARP1 SCAF11 SRRM2	9.07e-07	323	65	9	int:BARD1
Interaction	ZC3H14 interactions	SRRM1 SRSF6 SRSF7 ANLN SENP3 SH3KBP1 NCBP3	1.19e-06	169	65	7	int:ZC3H14
Interaction	DOT1L interactions	PCF11 ORC1 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ZC3H13 SENP3 MEPCE LARP1 SCAF11 SRRM2	1.48e-06	807	65	13	int:DOT1L
Interaction	SRSF1 interactions	SRRM1 SRSF2 HDAC5 SRSF6 SRSF7 ANLN SH3KBP1 MEPCE LARP1 SCAF11 SRRM2	1.89e-06	570	65	11	int:SRSF1
Interaction	LUC7L2 interactions	SNRNP27 SRSF6 SRSF7 SRRM4 MEPCE LARP1 SCAF11 SRRM2 NCBP3	1.89e-06	353	65	9	int:LUC7L2
Interaction	YWHAQ interactions	PANK2 HDAC5 SRSF6 ANLN ZC3H13 BAG3 AAK1 MEPCE MAP3K9 LARP1 FAM117B SORBS1 CCDC6 CDK14 DNMT1	2.00e-06	1118	65	15	int:YWHAQ
Interaction	SEPTIN2 interactions	GTF3C1 SRSF7 ANLN SH3KBP1 CCDC6 SRRM2 ACAP3	2.26e-06	186	65	7	int:SEPTIN2
Interaction	YWHAB interactions	PANK2 HDAC5 RASGRF1 ANLN BAG3 AAK1 MEPCE MAP3K9 LARP1 FAM117B SORBS1 CCDC6 CDK14 SRRM2	3.36e-06	1014	65	14	int:YWHAB
Interaction	SRSF11 interactions	SRRM1 SRSF2 SRSF6 SRSF7 SRRM4 SRRM2 NCBP3	4.03e-06	203	65	7	int:SRSF11
Interaction	EIF4A3 interactions	PCF11 SRRM1 SRSF2 HDAC5 SRSF6 SRSF7 ANLN ZC3H13 SRRM2 RBM20	4.18e-06	499	65	10	int:EIF4A3
Interaction	SNRPA1 interactions	SNRNP27 SRRM1 SRSF2 GTF3C1 SRSF7 ANLN MEPCE SRRM2	5.31e-06	300	65	8	int:SNRPA1
Interaction	SNRNP40 interactions	SNRNP27 SRRM1 SRSF6 SRSF7 NFATC2IP ANLN ZC3H13 MEPCE SCAF11 SRRM2 RBM20	5.48e-06	637	65	11	int:SNRNP40
Interaction	LARP1B interactions	SRSF6 SRSF7 MEPCE LARP1 CCDC140 PURG	5.71e-06	139	65	6	int:LARP1B
Interaction	PABPC5 interactions	ANLN ZC3H13 MEPCE LARP1 SRRM2 NCBP3	6.46e-06	142	65	6	int:PABPC5
Interaction	CPSF6 interactions	PCF11 SRRM1 SRSF6 SRSF7 ANLN BAG3 MEPCE SCAF11 SRRM2 NCBP3	6.65e-06	526	65	10	int:CPSF6
Interaction	ALYREF interactions	PCF11 SRRM1 SRSF2 SRSF7 ANLN ZC3H13 MEPCE SRRM2 NCBP3	7.18e-06	416	65	9	int:ALYREF
Interaction	RNPS1 interactions	SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ANLN SRRM4 SRRM2 NCBP3	8.52e-06	425	65	9	int:RNPS1
Interaction	SEPTIN7 interactions	GTF3C1 SRSF7 ANLN SH3KBP1 MAP3K9 SRRM2 ACAP3	8.63e-06	228	65	7	int:SEPTIN7
Interaction	SEPTIN8 interactions	ANLN SH3KBP1 CDK14 SRRM2 ACAP3	8.99e-06	87	65	5	int:SEPTIN8
Interaction	RBM25 interactions	SRRM1 HDAC5 SRSF7 ANLN SRRM4 MEPCE SRRM2 ACAP3	9.11e-06	323	65	8	int:RBM25
Interaction	TERF2IP interactions	PCF11 ORC1 GTF3C1 NFATC2IP ANLN MEPCE SCAF11 RREB1 SRRM2 DNMT1	1.01e-05	552	65	10	int:TERF2IP
Interaction	TRA2A interactions	SRRM1 SRSF6 SRSF7 ANLN MEPCE LARP1 SRRM2 NCBP3	1.06e-05	330	65	8	int:TRA2A
Interaction	U2AF1 interactions	SRSF2 SRSF7 ANLN SRRM4 MEPCE SCAF11 SRRM2	1.17e-05	239	65	7	int:U2AF1
Interaction	LUC7L interactions	SRRM1 SRSF6 SRSF7 SRRM4 MEPCE LARP1 SRRM2	1.27e-05	242	65	7	int:LUC7L
Interaction	SNRNP70 interactions	SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 RASGRF1 ZC3H13 SRRM4 MEPCE LARP1 SCAF11 SRRM2 NCBP3	1.28e-05	984	65	13	int:SNRNP70
Interaction	PRPF38A interactions	SRSF6 GTF3C1 SRSF7 ANLN SRRM4 MEPCE	1.33e-05	161	65	6	int:PRPF38A
Interaction	YWHAZ interactions	PANK2 HDAC5 RASGRF1 ANLN BAG3 AAK1 MEPCE MAP3K9 LARP1 SCAF11 FAM117B SORBS1 CCDC6 CDK14 DNMT1	1.48e-05	1319	65	15	int:YWHAZ
Interaction	SMC5 interactions	PCF11 SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 LARP1 SCAF11 RREB1 SRRM2 DNMT1 NCBP3	1.52e-05	1000	65	13	int:SMC5
Interaction	SF3A1 interactions	SNRNP27 SRRM1 HDAC5 SRSF7 ANLN CCDC6 RREB1 SRRM2 NCBP3	1.93e-05	471	65	9	int:SF3A1
Interaction	DHX16 interactions	PCF11 SNRNP27 SRRM1 SRSF6 ANLN SRRM2	1.99e-05	173	65	6	int:DHX16
Interaction	SRPK1 interactions	SRRM1 SRSF2 SRSF6 SRSF7 ANLN LARP1 SCAF11 SRRM2 PURG	2.13e-05	477	65	9	int:SRPK1
Interaction	PPP1CC interactions	SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 AAK1 LARP1 PPP1R14D CCDC6 SRRM2	2.17e-05	738	65	11	int:PPP1CC
Interaction	SPEN interactions	SNRNP27 SRSF2 SRSF6 SRSF7 ANLN SRRM2	2.34e-05	178	65	6	int:SPEN
Interaction	MYCN interactions	SNRNP27 SRRM1 SRSF2 HDAC5 SRSF6 GTF3C1 SRSF7 ZC3H13 MEPCE LARP1 SCAF11 PLEKHA6 SRRM2 DNMT1 NCBP3	2.38e-05	1373	65	15	int:MYCN
Interaction	EFHB interactions	ANLN MEPCE	3.07e-05	3	65	2	int:EFHB
Interaction	DHX15 interactions	SRRM1 HDAC5 GTF3C1 SRSF7 ANLN SENP3 MEPCE LARP1 SRRM2	3.18e-05	502	65	9	int:DHX15
Interaction	ELAVL2 interactions	SRSF6 AAK1 LARP1 SRRM2 PURG NCBP3	3.18e-05	188	65	6	int:ELAVL2
Interaction	LTV1 interactions	SRRM1 SRSF6 SRSF7 ANLN MEPCE PURG	4.02e-05	196	65	6	int:LTV1
Interaction	PRPF3 interactions	SNRNP27 SRRM1 SRSF2 SRSF7 ANLN MEPCE SRRM2	4.14e-05	291	65	7	int:PRPF3
Interaction	U2AF2 interactions	PCF11 SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 LARP1 SCAF11 SRRM2	4.16e-05	651	65	10	int:U2AF2
Interaction	HNRNPA1 interactions	PCF11 HDAC5 SRSF6 SRSF7 ANLN ZC3H13 MEPCE LARP1 SCAF11 RREB1 SRRM2 RBM20	4.26e-05	945	65	12	int:HNRNPA1
Interaction	MZT1 interactions	HDAC5 SRSF7 ZC3H13 SCAF11	4.48e-05	61	65	4	int:MZT1
Interaction	CSNK2A1 interactions	SRRM1 SRSF2 HDAC5 JADE2 ANLN ZC3H13 SENP3 SH3KBP1 MEPCE LARP1 CCDC6 SRRM2	4.77e-05	956	65	12	int:CSNK2A1
Interaction	ZFR interactions	SRSF6 SRSF7 ANLN SENP3 MEPCE PURG DNMT1	5.13e-05	301	65	7	int:ZFR
Interaction	SAP18 interactions	SRRM1 SRSF6 GTF3C1 SRSF7 ANLN ZC3H13 SRRM2	5.58e-05	305	65	7	int:SAP18
Interaction	SNIP1 interactions	SRRM1 SRSF6 SRSF7 SRRM4 MEPCE LARP1 SRRM2 NCBP3	5.65e-05	417	65	8	int:SNIP1
Interaction	RPS26P11 interactions	SRSF6 ANLN MEPCE CCDC140	5.76e-05	65	65	4	int:RPS26P11
Interaction	IFI27L1 interactions	PCF11 SNRNP27 ZC3H13 SCAF11	5.76e-05	65	65	4	int:IFI27L1
Interaction	PLRG1 interactions	PCF11 SRRM1 SRSF2 ANLN CCDC6 SRRM2	6.90e-05	216	65	6	int:PLRG1
Interaction	CWC15 interactions	SNRNP27 SRRM1 SRSF2 SRSF7 ANLN	7.23e-05	134	65	5	int:CWC15
Interaction	TOP1 interactions	PCF11 SRRM1 HDAC5 GTF3C1 ANLN MEPCE LARP1 SCAF11 CDK14 SRRM2	7.28e-05	696	65	10	int:TOP1
Interaction	CDC5L interactions	ORC1 SNRNP27 SRRM1 SRSF2 HDAC5 SRSF6 SRSF7 ANLN SENP3 SRRM2 PURG	8.26e-05	855	65	11	int:CDC5L
Interaction	PRPF40A interactions	SNRNP27 SRRM1 SRSF7 ANLN UBR4 MEPCE SRRM2 NCBP3	9.04e-05	446	65	8	int:PRPF40A
Interaction	H2BC8 interactions	SRSF2 GTF3C1 NFATC2IP ANLN MEPCE SCAF11 RREB1 DNMT1 NCBP3	9.18e-05	576	65	9	int:H2BC8
Interaction	CWC22 interactions	SNRNP27 SRSF2 SRSF7 ANLN SRRM2	9.20e-05	141	65	5	int:CWC22
Interaction	ZC3H18 interactions	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 SENP3 LARP1 SRRM2 PURG	1.03e-04	877	65	11	int:ZC3H18
Interaction	SUMO2 interactions	GTF3C1 NFATC2IP ANLN SENP3 UBR4 SCAF11 RREB1 SRRM2 DNMT1	1.12e-04	591	65	9	int:SUMO2
Interaction	SHCBP1 interactions	KRBA1 ANLN ZC3H13 SH3KBP1	1.12e-04	77	65	4	int:SHCBP1
Interaction	RBMX interactions	SRRM1 SRSF2 HDAC5 SRSF6 ANLN MEPCE LARP1 SRRM2	1.14e-04	461	65	8	int:RBMX
Interaction	SF3B4 interactions	SRRM1 SRSF2 SRSF6 ANLN BAG3 MEPCE SRRM2	1.14e-04	342	65	7	int:SF3B4
Interaction	GLYR1 interactions	SRSF6 SRSF7 ANLN MEPCE CCDC140 PURG	1.20e-04	239	65	6	int:GLYR1
Interaction	RBMXL1 interactions	SRSF6 SRSF7 ANLN MEPCE PURG	1.44e-04	155	65	5	int:RBMXL1
Interaction	NCBP3 interactions	SRSF6 SRSF7 ZC3H13 SENP3 NCBP3	1.48e-04	156	65	5	int:NCBP3
Interaction	DDX23 interactions	SRRM1 SRSF6 SRSF7 ZC3H13 SENP3 MEPCE SCAF11 SRRM2	1.50e-04	480	65	8	int:DDX23
Interaction	DHX40 interactions	PCF11 ZC3H13 MEPCE RREB1 RBM20 NCBP3	1.50e-04	249	65	6	int:DHX40
Interaction	USF1 interactions	PCF11 GTF3C1 UBR4 BAG3	1.64e-04	85	65	4	int:USF1
Interaction	EED interactions	ORC1 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 ANLN ZC3H13 SENP3 UBR4 ITGAE SRRM2 ITGB7 DNMT1	1.70e-04	1445	65	14	int:EED
Interaction	CIT interactions	SNRNP27 SRRM1 SRSF2 SRSF6 SRSF7 ANLN ZC3H13 UBR4 MEPCE LARP1 SCAF11 PLEKHA6 RREB1 SRRM2	1.76e-04	1450	65	14	int:CIT
Interaction	DDX50 interactions	SRSF6 SRSF7 ANLN MEPCE SRRM2 PURG	1.79e-04	257	65	6	int:DDX50
Interaction	H3C3 interactions	SRRM1 GTF3C1 NFATC2IP ANLN SCAF11 RREB1 DNMT1 NCBP3	1.85e-04	495	65	8	int:H3C3
Interaction	MECP2 interactions	PCF11 SNRNP27 SRRM1 SRSF2 SRSF6 GTF3C1 SRSF7 NRXN2 ANLN ZC3H13 MEPCE SRRM2 DNMT1	2.01e-04	1287	65	13	int:MECP2
Interaction	MAGOH interactions	SRRM1 SRSF2 SRSF6 SRSF7 ZC3H13 SRRM2	2.06e-04	264	65	6	int:MAGOH
Interaction	CENPA interactions	GTF3C1 NFATC2IP ZC3H13 SENP3 RREB1 DNMT1 NCBP3	2.08e-04	377	65	7	int:CENPA
Interaction	SUZ12 interactions	SRSF6 GTF3C1 SRSF7 ZC3H13 SENP3 LARP1 SCAF11 DNMT1 NCBP3	2.13e-04	644	65	9	int:SUZ12
Interaction	EZH1 interactions	SNRNP27 ZC3H13 SCAF11 NCBP3	2.23e-04	92	65	4	int:EZH1
Interaction	HSP90AA5P interactions	ANLN MEPCE CDK14 MAP3K6	2.32e-04	93	65	4	int:HSP90AA5P
Interaction	TRA2B interactions	SRRM1 SRSF2 SRSF6 SRSF7 ANLN MEPCE SRRM2	2.36e-04	385	65	7	int:TRA2B
Interaction	GNL2 interactions	SNRNP27 SRSF6 SRSF7 NFATC2IP ANLN ZC3H13 PURG	2.40e-04	386	65	7	int:GNL2
Interaction	RBM23 interactions	SRRM1 SRSF6 GTF3C1 ANLN	2.42e-04	94	65	4	int:RBM23
Interaction	SF3A2 interactions	SRRM1 SRSF2 SRSF6 SRSF7 ANLN SRRM2	2.47e-04	273	65	6	int:SF3A2
Interaction	SF3B2 interactions	SRRM1 SRSF2 HDAC5 ANLN BAG3 MEPCE SRRM2 CCDC140	2.48e-04	517	65	8	int:SF3B2
Interaction	PARP1 interactions	SNRNP27 SRRM1 SRSF2 HDAC5 GTF3C1 NFATC2IP ANLN SENP3 BAG3 MEPCE SCAF11 RREB1 DNMT1	2.50e-04	1316	65	13	int:PARP1
Interaction	LINC02910 interactions	SNRNP27 ZC3H13 SCAF11 NCBP3	2.52e-04	95	65	4	int:LINC02910
Interaction	BMI1 interactions	SRRM1 SRSF6 GTF3C1 SRSF7 ZC3H13 MEPCE LARP1 SCAF11 NCBP3	2.52e-04	659	65	9	int:BMI1
Interaction	RPLP0 interactions	SRRM1 HDAC5 SRSF6 ANLN SENP3 MEPCE LARP1 CCDC140 PURG	2.55e-04	660	65	9	int:RPLP0
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF2 SRSF6 SRSF7	1.44e-06	12	35	3	737
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 ANLN PLEKHA6 ACAP3	6.50e-04	206	35	4	682
GeneFamily	RNA binding motif containing	SRSF2 SRSF6 SRSF7 RBM20	7.36e-04	213	35	4	725
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K9 MAP3K6	9.78e-04	24	35	2	654
Coexpression	BENPORATH_CYCLING_GENES	PCF11 ORC1 PANK2 SRSF7 JADE2 ANLN BAG3 MEPCE LARP1 ACAP3	4.83e-06	648	66	10	M8156
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ANLN SRRM4 ITGAE MAP3K6	5.86e-06	173	66	5	a5b6c3d58f7a8e533330798b81496009a31548af
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ANLN SRRM4 ITGAE MAP3K6	5.86e-06	173	66	5	cc094992b8027f4cef38f0fb0b76f0d07210d1e2
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCF11 SRRM1 SRSF7 SCAF11 SRRM2	8.55e-06	187	66	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	SYCP2 ZC3H13 RIMS2 SRRM2 DNMT1	1.10e-05	197	66	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	3'-Adult-Distal_Rectal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRSF6 BAG3 AAK1 SORBS1 SRRM2	1.13e-05	198	66	5	7ad7726fc405806b1d7824f58548073ea5e0c70b
ToppCell	3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRSF6 BAG3 AAK1 SORBS1 SRRM2	1.13e-05	198	66	5	1fbec311f2c987ca90a023a5989128c05aa12d5c
ToppCell	3'-Adult-Distal_Rectal-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRSF6 BAG3 AAK1 SORBS1 SRRM2	1.13e-05	198	66	5	ceede961ad9af6a3159db7efaa5087bf38aafc2d
ToppCell	3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRSF6 BAG3 AAK1 SORBS1 SRRM2	1.13e-05	198	66	5	4f26a60e99f42343e5af7221723e108a1a1b7827
ToppCell	severe-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SRRM1 GTF3C1 SRSF7 SRRM2 ITGB7	1.18e-05	200	66	5	6aa77955017d073a96324e4db6b9950a2ec46cf8
Disease	clear cell renal cell carcinoma (is_marker_for)	SRSF2 SRSF6 SRSF7	5.56e-05	33	66	3	DOID:4467 (is_marker_for)
Disease	HWESASXX measurement	CNMD RREB1	1.03e-04	7	66	2	EFO_0021147
Disease	atrial fibrillation (is_implicated_in)	VWF KCNQ1	4.41e-04	14	66	2	DOID:0060224 (is_implicated_in)
Disease	monocyte measurement	SNRNP27 FAM117B RBM20	8.34e-04	82	66	3	EFO_0803547
Disease	bone density	HROB ADAMTSL1 SGIP1 HDAC5 RREB1	1.77e-03	388	66	5	EFO_0003923
Disease	Primary familial dilated cardiomyopathy	BAG3 RBM20	2.06e-03	30	66	2	cv:C0340427

Protein segments in the cluster

Peptide	Gene	Start	Entry
PSPSPRITRKSTRQT	DNMT1	151	P26358
PPSSPKTQRAGHRRI	AAK1	621	Q2M2I8
PHSSPRAPTARRKVR	ACAP3	541	Q96P50
SHGITRPSPRRSNSP	CCDC6	406	Q16204
ESPKVRRHSSPSSPT	CDK14	111	O94921
ARPRTRTLPTPHSFK	CCDC140	121	Q96MF4
RSPVSRSLSPRSHTP	RBM20	636	Q5T481
HVSAPRTARPKPRVS	CFAP99	596	D6REC4
RTPRTPRTPQLKDSS	LARP1	781	Q6PKG0
IRKAPRSHTLLSPSP	KCNQ1	396	P51787
PSPPTHSPSRRKSHR	KRBA1	176	A5PL33
VISAPPSSSSRHRKR	MEPCE	351	Q7L2J0
RSSTLSISRVPHPKL	ERVS71-1	166	P61550
FIPKTRSTPRPTARA	HHIPL1	606	Q96JK4
RSTPHRTPIITPNTK	ANLN	391	Q9NQW6
PPSRKTTSPVSHRKA	KIAA1614	811	Q5VZ46
KPSERRTSPVTLSPH	ADAMTSL1	1121	Q8N6G6
TSPRTKRTPGPLHRC	ITGAE	56	P38570
KPPRRTSSHLPSSPA	JADE2	646	Q9NQC1
LQPGKRSRSPSSPRH	MAP3K6	906	O95382
TDRTTLLSPRKPAPR	NRXN2	1521	Q9P2S2
HSRPRPPVSSTKSDI	NCBP3	476	Q53F19
PTHPSTRAKTRRFPG	HROB	386	Q8N3J3
TRLPKTVATTRPTPH	MUC5AC	1681	P98088
STVPSKLRHPCPTRL	ITGB7	206	P26010
RSRSPKSRSPIIHSP	PCF11	481	O94913
GTRIPSSTTLSPPRH	PANK2	31	Q9BZ23
AQRTTNHSPPTPRRS	RIMS2	456	Q9UQ26
SRQTPTHPLTPRARK	ORC1	221	Q13415
SSTSPRAPPSHRPLK	PILRA	276	Q9UKJ1
AAPTPTHRRTSAIPR	APC2	1521	O95996
SRSNGSVSRKPRPPH	IGSF11	386	Q5DX21
HRAPPPLVQRSSSTR	FAM117B	376	Q6P1L5
LHSQPPKTRRTSSLR	FAM47A	491	Q5JRC9
QSPRSPSSKRPSLHR	KNDC1	981	Q76NI1
KLPRHRPLSRTQSSP	HDAC5	486	Q9UQL6
KRTPASRPSARRTPI	CHADL	731	Q6NUI6
ARSSTPLHSPSPIRV	BAG3	281	O95817
KPRTRRSRFHSPSTT	SCAF11	786	Q99590
SSRPRRSTSPPSRKL	MAP3K9	801	P80192
RSPPVGRKASPTRTH	PCARE	986	A6NGG8
SRRRQKHSAPSPPVS	PURG	146	Q9UJV8
SHPDSSKIPRSRRPS	PPP1R14D	41	Q9NXH3
RSRSRSPPPVSKRES	SRSF2	186	Q01130
KSRTPPRRRSSRSSP	SRRM2	1681	Q9UQ35
SSSPETRSRTPPRHR	SRRM2	1711	Q9UQ35
PRTKTTSRRGRSPSP	SRRM2	1751	Q9UQ35
PTSRKRSRSRTSPAP	SRRM2	1846	Q9UQ35
PKRINAVSHLPSRTP	TEX48	56	A0A1B0GUV7
SRSPRRHRSTSPSPS	SNRNP27	51	Q8WVK2
RHRSTSPSPSRLKER	SNRNP27	56	Q8WVK2
LSHPTTSRPKATGRR	SH3KBP1	476	Q96B97
SSRKHLPTLPTLLSR	SHOC1	96	Q5VXU9
SPPPKRATSRSRSRS	SRSF6	316	Q13247
SPPSPRTKSRTHTRA	NFATC2IP	201	Q8NCF5
PPLSITKTSSPSRRR	RASGRF1	741	Q13972
VPTTTKRPHSGPRSN	CNMD	221	O75829
PRPSRPTHRKTCSQR	SENP3	111	Q9H4L4
RLSLQPRSHSVPRSP	PLEKHA6	446	Q9Y2H5
PLSHRSKRSLSCRPP	VWF	756	P04275
ATAPPSPLKRRRLSS	RREB1	156	Q92766
IALSPSPVRKSPRRS	SGIP1	146	Q9BQI5
KSRSPSPRRRSSPVR	SRRM1	176	Q8IYB3
RRHSPSRSASPSPRK	SRRM1	521	Q8IYB3
RPLFLPRHTPTKSNT	SYCP2	1181	Q9BX26
KLITPAPSSLPHSRR	SORBS1	961	Q9BX66
KRSPPSRSSRSRRSP	SRRM4	441	A7MD48
PRSSRSKSRSPSPKR	SRSF7	206	Q16629
PSLITPVSSKRHLTR	TMEM104	291	Q8NE00
TPPRESLRTSHRASP	nan	216	Q9UF83
SLRTSHRASPTRMPP	nan	221	Q9UF83
RSPPTASLRRTPSRA	nan	36	A8MUU9
SRTRTPPRASLKRTP	nan	51	A8MUU9
PPRASLKRTPSRASL	nan	56	A8MUU9
PPTASRTRSLPRASR	nan	101	A8MUU9
TPPRASLRRTPSRAS	nan	136	A8MUU9
PSRASRTRTPPRASL	nan	146	A8MUU9
APPSHSPRGTKRRAS	GTF3C1	1851	Q12789
RRHVTLPSSPRSNTP	UBR4	2711	Q5T4S7
SIQRHSPSPRRKRTP	ZC3H13	341	Q5T200
SHSLSSPQRKQSPPR	ZC3H13	376	Q5T200