Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein kinase activity	EPHB2 PHKA2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6 EPHA7	4.03e-07	600	89	14	GO:0004672
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3 VDAC1	1.54e-06	182	89	8	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3 VDAC1	1.67e-06	184	89	8	GO:0022832
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	EPHB2 PHKA2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6 EPHA7	2.89e-06	709	89	14	GO:0016773
GeneOntologyMolecularFunction	kinase activity	EPHB2 PHKA2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6 EPHA7	6.82e-06	764	89	14	GO:0016301
GeneOntologyMolecularFunction	medium-chain fatty acid omega-hydroxylase activity	CYP4A11 CYP4A22	1.96e-05	2	89	2	GO:0140981
GeneOntologyMolecularFunction	16-hydroxypalmitate dehydrogenase activity	CYP4A11 CYP4A22	1.96e-05	2	89	2	GO:0103002
GeneOntologyMolecularFunction	protein dimerization activity	TYR STK10 KLHL2 PTPA EPM2A GLA ERN1 CAMK2D STK26 LPL LRP6 GABBR2 G6PD EPAS1 GABBR1 TP53BP2 NPAS1	2.02e-05	1205	89	17	GO:0046983
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	PHKA2 STK10 BMPR2 ERN1 CAMK2D STK26 GRK5 PAK5 PAK3 PAK6	2.94e-05	446	89	10	GO:0004674
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHB2 EPHA6 EPHA7	3.75e-05	15	89	3	GO:0005005
GeneOntologyMolecularFunction	G protein-coupled GABA receptor activity	GABBR2 GABBR1	5.88e-05	3	89	2	GO:0004965
GeneOntologyMolecularFunction	protein homodimerization activity	TYR STK10 KLHL2 PTPA EPM2A GLA ERN1 CAMK2D STK26 LPL LRP6 G6PD TP53BP2	6.34e-05	815	89	13	GO:0042803
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	EPHB2 PHKA2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6 EPHA7	6.60e-05	938	89	14	GO:0016772
GeneOntologyMolecularFunction	ephrin receptor activity	EPHB2 EPHA6 EPHA7	7.88e-05	19	89	3	GO:0005003
GeneOntologyMolecularFunction	gated channel activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3 VDAC1	1.23e-04	334	89	8	GO:0022836
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A CACNA1H	2.07e-04	26	89	3	GO:0005248
GeneOntologyMolecularFunction	leukotriene-B4 20-monooxygenase activity	CYP4A11 CYP4A22	4.07e-04	7	89	2	GO:0050051
GeneOntologyMolecularFunction	alkane 1-monooxygenase activity	CYP4A11 CYP4A22	4.07e-04	7	89	2	GO:0018685
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	EPHB2 BMPR2 EPHA6 EPHA7	5.67e-04	85	89	4	GO:0019199
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3	8.57e-04	343	89	7	GO:0005261
GeneOntologyMolecularFunction	arachidonate omega-hydroxylase activity	CYP4A11 CYP4A22	8.64e-04	10	89	2	GO:0052869
GeneOntologyMolecularFunction	fatty acid omega-hydroxylase activity	CYP4A11 CYP4A22	8.64e-04	10	89	2	GO:0120250
GeneOntologyMolecularFunction	long-chain fatty acid omega-hydroxylase activity	CYP4A11 CYP4A22	8.64e-04	10	89	2	GO:0102033
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3 VDAC1	1.02e-03	459	89	8	GO:0005216
GeneOntologyMolecularFunction	protein serine kinase activity	STK10 ERN1 CAMK2D STK26 PAK5 PAK3 PAK6	1.19e-03	363	89	7	GO:0106310
GeneOntologyMolecularFunction	FK506 binding	FKBP10 FKBP5	1.26e-03	12	89	2	GO:0005528
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	FKBP10 PTPA FKBP5	1.44e-03	50	89	3	GO:0003755
GeneOntologyMolecularFunction	axon guidance receptor activity	EPHB2 EPHA7	1.48e-03	13	89	2	GO:0008046
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	CYP4A11 CYP4A22	1.48e-03	13	89	2	GO:0016713
GeneOntologyMolecularFunction	sodium channel activity	SCN1A SCN2A CACNA1H	1.62e-03	52	89	3	GO:0005272
GeneOntologyMolecularFunction	cis-trans isomerase activity	FKBP10 PTPA FKBP5	1.71e-03	53	89	3	GO:0016859
GeneOntologyMolecularFunction	macrolide binding	FKBP10 FKBP5	1.73e-03	14	89	2	GO:0005527
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A	1.73e-03	14	89	2	GO:0031402
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1F CACNA1H	1.73e-03	14	89	2	GO:0008331
GeneOntologyMolecularFunction	arachidonate binding	CYP4A11 CYP4A22	1.99e-03	15	89	2	GO:0050544
GeneOntologyMolecularFunction	icosanoid binding	CYP4A11 CYP4A22	2.26e-03	16	89	2	GO:0050542
GeneOntologyMolecularFunction	icosatetraenoic acid binding	CYP4A11 CYP4A22	2.26e-03	16	89	2	GO:0050543
GeneOntologyMolecularFunction	channel activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3 VDAC1	2.37e-03	525	89	8	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3 VDAC1	2.40e-03	526	89	8	GO:0022803
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	SCN1A SCN2A	2.56e-03	17	89	2	GO:0099508
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH2 DNAH5	2.87e-03	18	89	2	GO:0008569
GeneOntologyMolecularFunction	steroid binding	OSBPL9 OSBP2 VDAC1 SULT1E1	2.97e-03	133	89	4	GO:0005496
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	EPHB2 EPHA6 EPHA7	3.06e-03	65	89	3	GO:0004714
GeneOntologyMolecularFunction	apolipoprotein binding	LPL LRP6	3.54e-03	20	89	2	GO:0034185
GeneOntologyMolecularFunction	ceramide binding	PLA2G4A VDAC1	3.54e-03	20	89	2	GO:0097001
GeneOntologyMolecularFunction	sterol binding	OSBPL9 OSBP2 VDAC1	3.93e-03	71	89	3	GO:0032934
GeneOntologyMolecularFunction	protein tyrosine kinase activity	EPHB2 EPHA6 SCYL1 EPHA7	4.04e-03	145	89	4	GO:0004713
GeneOntologyMolecularFunction	GABA receptor activity	GABBR2 GABBR1	4.28e-03	22	89	2	GO:0016917
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1F SCN1A SCN2A KCNK5 CACNA1H GRIN2C KCNG3	4.74e-03	465	89	7	GO:0046873
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1F KCNK5 CACNA1H KCNG3	4.78e-03	152	89	4	GO:0022843
GeneOntologyMolecularFunction	arachidonate epoxygenase activity	CYP4A11 CYP4A22	5.09e-03	24	89	2	GO:0008392
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A	5.96e-03	26	89	2	GO:0031420
GeneOntologyMolecularFunction	calcium/calmodulin-dependent protein kinase activity	PHKA2 CAMK2D	6.41e-03	27	89	2	GO:0004683
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP4A11 CYP4A22	6.41e-03	27	89	2	GO:0008391
GeneOntologyMolecularFunction	long-chain fatty acid binding	CYP4A11 CYP4A22	6.89e-03	28	89	2	GO:0036041
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH2 DNAH5	6.89e-03	28	89	2	GO:0051959
GeneOntologyMolecularFunction	mannosyltransferase activity	ALG3 ALG1	6.89e-03	28	89	2	GO:0000030
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1F PTPA TMEM249 SCN1A SCN2A KCNK5 CACNA1H ATP5MJ GRIN2C KCNG3	5.25e-06	378	90	10	GO:0034702
GeneOntologyCellularComponent	cation channel complex	CACNA1F PTPA TMEM249 SCN1A SCN2A CACNA1H ATP5MJ KCNG3	7.94e-06	235	90	8	GO:0034703
GeneOntologyCellularComponent	G protein-coupled GABA receptor complex	GABBR2 GABBR1	1.83e-05	2	90	2	GO:1902712
GeneOntologyCellularComponent	presynaptic membrane	EPHB2 SCN1A SCN2A NTNG1 CACNA1H GABBR2 GABBR1 VDAC1	2.60e-05	277	90	8	GO:0042734
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A CACNA1H	5.02e-05	17	90	3	GO:0001518
GeneOntologyCellularComponent	G protein-coupled receptor heterodimeric complex	GABBR2 GABBR1	5.48e-05	3	90	2	GO:0038039
GeneOntologyCellularComponent	membrane protein complex	CACNA1F PTPA ERN1 TMEM249 SCN1A SCN2A SOCS4 SCYL1 KCNK5 LRP6 CACNA1H ATP5MJ GRIN2C DENND5A GABBR2 KCNG3 GABBR1 VDAC1	5.95e-05	1498	90	18	GO:0098796
GeneOntologyCellularComponent	transmembrane transporter complex	CACNA1F PTPA TMEM249 SCN1A SCN2A KCNK5 CACNA1H ATP5MJ GRIN2C KCNG3	8.40e-05	523	90	10	GO:1902495
GeneOntologyCellularComponent	transporter complex	CACNA1F PTPA TMEM249 SCN1A SCN2A KCNK5 CACNA1H ATP5MJ GRIN2C KCNG3	1.27e-04	550	90	10	GO:1990351
GeneOntologyCellularComponent	synaptic membrane	EPHB2 SCN1A SCN2A NTNG1 CACNA1H GRIN2C GABBR2 GABBR1 VDAC1 EPHA7	2.04e-04	583	90	10	GO:0097060
GeneOntologyCellularComponent	axon initial segment	CAMK2D SCN1A SCN2A	2.60e-04	29	90	3	GO:0043194
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A CACNA1H	2.60e-04	29	90	3	GO:0034706
GeneOntologyCellularComponent	calcium channel complex	CACNA1F PTPA TMEM249 CACNA1H	2.79e-04	73	90	4	GO:0034704
GeneOntologyCellularComponent	G protein-coupled receptor dimeric complex	GABBR2 GABBR1	3.80e-04	7	90	2	GO:0038037
GeneOntologyCellularComponent	postsynapse	EPHB2 BMPR2 GPR50 CAMK2D CASKIN1 PAK3 CACNA1H GRIN2C PAK6 GABBR2 GABBR1 VDAC1 EPHA7	4.05e-04	1018	90	13	GO:0098794
GeneOntologyCellularComponent	main axon	CAMK2D SCN1A SCN2A GABBR1	5.93e-04	89	90	4	GO:0044304
GeneOntologyCellularComponent	neuronal cell body	EPHB2 CACNA1F BMPR2 EPM2A CAMK2D SCN1A CASP6 LRP6 CACNA1H GABBR1 EPHA7	9.06e-04	835	90	11	GO:0043025
GeneOntologyCellularComponent	G protein-coupled receptor complex	GABBR2 GABBR1	9.83e-04	11	90	2	GO:0097648
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1F TMEM249 CACNA1H	1.02e-03	46	90	3	GO:0005891
GeneOntologyCellularComponent	postsynaptic membrane	EPHB2 CACNA1H GRIN2C GABBR2 GABBR1 VDAC1 EPHA7	1.83e-03	405	90	7	GO:0045211
GeneOntologyCellularComponent	neuron to neuron synapse	EPHB2 BMPR2 GPR50 PAK3 GRIN2C PAK6 VDAC1 EPHA7	1.87e-03	523	90	8	GO:0098984
GeneOntologyCellularComponent	plasma membrane protein complex	CACNA1F TMEM249 SCN1A SCN2A LRP6 CACNA1H GRIN2C GABBR2 KCNG3 GABBR1	2.00e-03	785	90	10	GO:0098797
GeneOntologyCellularComponent	cell body	EPHB2 CACNA1F BMPR2 EPM2A CAMK2D SCN1A CASP6 LRP6 CACNA1H GABBR1 EPHA7	2.12e-03	929	90	11	GO:0044297
GeneOntologyCellularComponent	somatodendritic compartment	EPHB2 CACNA1F BMPR2 EPM2A EPHA6 CAMK2D SCN1A CASP6 LRP6 CACNA1H OSBP2 GABBR1 EPHA7	2.25e-03	1228	90	13	GO:0036477
GeneOntologyCellularComponent	glutamatergic synapse	EPHB2 CASKIN1 SCN2A NTNG1 PAK3 CACNA1H GRIN2C GABBR2 GABBR1 EPHA7	2.68e-03	817	90	10	GO:0098978
GeneOntologyCellularComponent	intercalated disc	CAMK2D SCN1A SCN2A	3.16e-03	68	90	3	GO:0014704
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A	3.31e-03	20	90	2	GO:0033268
GeneOntologyCellularComponent	postsynaptic density	BMPR2 GPR50 PAK3 GRIN2C PAK6 VDAC1 EPHA7	3.33e-03	451	90	7	GO:0014069
GeneOntologyCellularComponent	GABA receptor complex	GABBR2 GABBR1	3.65e-03	21	90	2	GO:1902710
GeneOntologyCellularComponent	cytoplasmic side of endoplasmic reticulum membrane	EPM2A ALG1	4.00e-03	22	90	2	GO:0098554
GeneOntologyCellularComponent	asymmetric synapse	BMPR2 GPR50 PAK3 GRIN2C PAK6 VDAC1 EPHA7	4.52e-03	477	90	7	GO:0032279
GeneOntologyCellularComponent	presynaptic active zone membrane	NTNG1 CACNA1H VDAC1	4.65e-03	78	90	3	GO:0048787
GeneOntologyCellularComponent	T-tubule	CAMK2D SCN1A SCN2A	4.82e-03	79	90	3	GO:0030315
GeneOntologyCellularComponent	axonemal dynein complex	DNAH2 DNAH5	5.16e-03	25	90	2	GO:0005858
GeneOntologyCellularComponent	postsynaptic specialization	BMPR2 GPR50 PAK3 GRIN2C PAK6 VDAC1 EPHA7	6.01e-03	503	90	7	GO:0099572
MousePheno	abnormal vascular resistance	BMPR2 CYP4A11 PLA2G4A CYP4A22	2.94e-06	19	76	4	MP:0005532
MousePheno	clonic seizures	SCN1A GABBR2 GABBR1	5.38e-05	14	76	3	MP:0003996
MousePheno	abnormal long-term spatial reference memory	SCN1A CASKIN1 PAK3 GABBR2	7.01e-05	41	76	4	MP:0008432
Domain	Prot_kinase_dom	EPHB2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6 EPHA7	6.07e-07	489	90	13	IPR000719
Domain	PROTEIN_KINASE_DOM	EPHB2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6 EPHA7	6.65e-07	493	90	13	PS50011
Domain	Kinase-like_dom	EPHB2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6 EPHA7	1.91e-06	542	90	13	IPR011009
Domain	PROTEIN_KINASE_ATP	EPHB2 STK10 BMPR2 EPHA6 ERN1 CAMK2D STK26 GRK5 PAK5 PAK3 PAK6 EPHA7	2.03e-06	459	90	12	PS00107
Domain	Protein_kinase_ATP_BS	EPHB2 STK10 BMPR2 EPHA6 CAMK2D STK26 GRK5 PAK5 PAK3 PAK6 EPHA7	2.06e-06	379	90	11	IPR017441
Domain	Channel_four-helix_dom	CACNA1F SCN1A SCN2A CACNA1H KCNG3	7.98e-06	57	90	5	IPR027359
Domain	-	CACNA1F SCN1A SCN2A CACNA1H KCNG3	7.98e-06	57	90	5	1.20.120.350
Domain	Pkinase	STK10 BMPR2 ERN1 CAMK2D STK26 GRK5 PAK5 SCYL1 PAK3 PAK6	1.49e-05	381	90	10	PF00069
Domain	RECEPTOR_TYR_KIN_V_2	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	PS00790
Domain	Eph_TM	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	IPR001426
Domain	EPH_lbd	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	SM00615
Domain	Ephrin_lbd	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	PF01404
Domain	EphA2_TM	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	IPR001090
Domain	EPH_LBD	EPHB2 EPHA6 EPHA7	3.79e-05	14	90	3	PS51550
Domain	PBD	PAK5 PAK3 PAK6	5.79e-05	16	90	3	SM00285
Domain	PROTEIN_KINASE_ST	STK10 BMPR2 ERN1 CAMK2D STK26 GRK5 PAK5 PAK3 PAK6	6.20e-05	362	90	9	PS00108
Domain	GPCR3_GABA-B	GABBR2 GABBR1	6.87e-05	3	90	2	IPR002455
Domain	PBD	PAK5 PAK3 PAK6	7.01e-05	17	90	3	PF00786
Domain	CRIB	PAK5 PAK3 PAK6	1.16e-04	20	90	3	PS50108
Domain	CRIB_dom	PAK5 PAK3 PAK6	1.35e-04	21	90	3	IPR000095
Domain	Ion_trans_dom	CACNA1F SCN1A SCN2A CACNA1H KCNG3	2.26e-04	114	90	5	IPR005821
Domain	Ion_trans	CACNA1F SCN1A SCN2A CACNA1H KCNG3	2.26e-04	114	90	5	PF00520
Domain	DOCK_N	DOCK2 DOCK5	2.27e-04	5	90	2	PF16172
Domain	DOCK_N	DOCK2 DOCK5	2.27e-04	5	90	2	IPR032376
Domain	Ephrin_rec_like	EPHB2 EPHA6 EPHA7	2.30e-04	25	90	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB2 EPHA6 EPHA7	2.30e-04	25	90	3	IPR011641
Domain	SAM_1	EPHB2 EPHA6 CASKIN1 EPHA7	3.24e-04	68	90	4	PF00536
Domain	Ser/Thr_kinase_AS	STK10 BMPR2 ERN1 CAMK2D GRK5 PAK5 PAK3 PAK6	3.27e-04	357	90	8	IPR008271
Domain	S_TKc	STK10 ERN1 CAMK2D STK26 GRK5 PAK5 PAK3 PAK6	3.39e-04	359	90	8	SM00220
Domain	Na_trans_cytopl	SCN1A SCN2A	3.40e-04	6	90	2	PF11933
Domain	PAK_BD	PAK5 PAK3	3.40e-04	6	90	2	IPR033923
Domain	Na_trans_cytopl	SCN1A SCN2A	3.40e-04	6	90	2	IPR024583
Domain	-	EPHB2 EPHA6 NTNG1 EPHA7	4.26e-04	73	90	4	2.60.120.260
Domain	WASP_C	PAK5 PAK6	4.75e-04	7	90	2	IPR011026
Domain	SH3	DOCK2 DOCK5 SH3TC1 CASKIN1 PPP1R13B TP53BP2	6.20e-04	216	90	6	SM00326
Domain	SH3	DOCK2 DOCK5 SH3TC1 CASKIN1 PPP1R13B TP53BP2	6.20e-04	216	90	6	PS50002
Domain	DHC_N1	DNAH2 DNAH5	6.31e-04	8	90	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH2 DNAH5	6.31e-04	8	90	2	IPR013594
Domain	SH3_domain	DOCK2 DOCK5 SH3TC1 CASKIN1 PPP1R13B TP53BP2	6.82e-04	220	90	6	IPR001452
Domain	ANF_lig-bd_rcpt	GRIN2C GABBR2 GABBR1	7.47e-04	37	90	3	IPR001828
Domain	ANF_receptor	GRIN2C GABBR2 GABBR1	7.47e-04	37	90	3	PF01094
Domain	SAM	EPHB2 EPHA6 CASKIN1 EPHA7	8.63e-04	88	90	4	SM00454
Domain	Peripla_BP_I	GRIN2C GABBR2 GABBR1	8.72e-04	39	90	3	IPR028082
Domain	Na_channel_asu	SCN1A SCN2A	1.01e-03	10	90	2	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A	1.01e-03	10	90	2	IPR010526
Domain	VDCCAlpha1	CACNA1F CACNA1H	1.01e-03	10	90	2	IPR002077
Domain	Na_trans_assoc	SCN1A SCN2A	1.01e-03	10	90	2	PF06512
Domain	Galactose-bd-like	EPHB2 EPHA6 NTNG1 EPHA7	1.10e-03	94	90	4	IPR008979
Domain	SAM_DOMAIN	EPHB2 EPHA6 CASKIN1 EPHA7	1.15e-03	95	90	4	PS50105
Domain	Ephrin_rec_like	EPHB2 EPHA7	1.23e-03	11	90	2	PF07699
Domain	DOCK_C	DOCK2 DOCK5	1.23e-03	11	90	2	IPR010703
Domain	DHR-1_domain	DOCK2 DOCK5	1.23e-03	11	90	2	IPR027007
Domain	DHR_2	DOCK2 DOCK5	1.23e-03	11	90	2	PS51651
Domain	DHR_1	DOCK2 DOCK5	1.23e-03	11	90	2	PS51650
Domain	DOCK-C2	DOCK2 DOCK5	1.23e-03	11	90	2	PF14429
Domain	DHR-2	DOCK2 DOCK5	1.23e-03	11	90	2	IPR027357
Domain	DHR-2	DOCK2 DOCK5	1.23e-03	11	90	2	PF06920
Domain	DOCK	DOCK2 DOCK5	1.23e-03	11	90	2	IPR026791
Domain	SAM	EPHB2 EPHA6 CASKIN1 EPHA7	1.24e-03	97	90	4	IPR001660
Domain	-	PAK5 PAK3	1.47e-03	12	90	2	3.90.810.10
Domain	Oxysterol-bd	OSBPL9 OSBP2	1.47e-03	12	90	2	IPR000648
Domain	Oxysterol-bd_CS	OSBPL9 OSBP2	1.47e-03	12	90	2	IPR018494
Domain	Oxysterol_BP	OSBPL9 OSBP2	1.47e-03	12	90	2	PF01237
Domain	OSBP	OSBPL9 OSBP2	1.47e-03	12	90	2	PS01013
Domain	-	EPHB2 EPHA6 CASKIN1 EPHA7	1.72e-03	106	90	4	1.10.150.50
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH5	2.01e-03	14	90	2	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DNAH5	2.01e-03	14	90	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DNAH5	2.01e-03	14	90	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH5	2.01e-03	14	90	2	PF08393
Domain	MT	DNAH2 DNAH5	2.01e-03	14	90	2	PF12777
Domain	AAA_8	DNAH2 DNAH5	2.01e-03	14	90	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH5	2.01e-03	14	90	2	IPR011704
Domain	AAA_5	DNAH2 DNAH5	2.01e-03	14	90	2	PF07728
Domain	DHC_fam	DNAH2 DNAH5	2.31e-03	15	90	2	IPR026983
Domain	Dynein_heavy_dom	DNAH2 DNAH5	2.31e-03	15	90	2	IPR004273
Domain	Dynein_heavy	DNAH2 DNAH5	2.31e-03	15	90	2	PF03028
Domain	SAM/pointed	EPHB2 EPHA6 CASKIN1 EPHA7	2.47e-03	117	90	4	IPR013761
Domain	FKBP_PPIASE	FKBP10 FKBP5	2.64e-03	16	90	2	PS50059
Domain	FKBP_C	FKBP10 FKBP5	2.64e-03	16	90	2	PF00254
Domain	PPIase_FKBP	FKBP10 FKBP5	2.98e-03	17	90	2	IPR023566
Domain	PPIase_FKBP_dom	FKBP10 FKBP5	4.12e-03	20	90	2	IPR001179
Domain	PLAT	LPL DENND5A	4.54e-03	21	90	2	PS50095
Domain	-	LPL DENND5A	4.54e-03	21	90	2	2.60.60.20
Domain	PLAT	LPL DENND5A	4.54e-03	21	90	2	PF01477
Domain	PLAT/LH2_dom	LPL DENND5A	4.54e-03	21	90	2	IPR001024
Pathway	KEGG_AXON_GUIDANCE	EPHB2 EPHA6 PAK5 NTNG1 PAK3 PAK6 EPHA7	5.40e-06	129	75	7	M5539
Pathway	REACTOME_ACTIVATION_OF_RAC1	PAK5 PAK3 PAK6	3.98e-05	13	75	3	M6322
Pathway	WP_NEURAL_CREST_CELL_MIGRATION_DURING_DEVELOPMENT	EPHB2 PAK5 PAK3 PAK6	5.84e-05	40	75	4	M39798
Pathway	WP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER	EPHB2 PAK5 PAK3 PAK6	7.79e-05	43	75	4	M39788
Pathway	SIG_CHEMOTAXIS	PAK5 PAK3 PPP1R13B PAK6	9.33e-05	45	75	4	M5193
Pathway	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX	ABCC1 CYP4A11 CYP4A22	1.80e-04	21	75	3	M27137
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1F CACNA1H VDAC1	2.37e-04	23	75	3	M47666
Pathway	REACTOME_ARACHIDONIC_ACID_METABOLISM	ABCC1 CYP4A11 PLA2G4A CYP4A22	2.70e-04	59	75	4	M27140
Pathway	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX	ABCC1 CYP4A11 CYP4A22	3.06e-04	25	75	3	MM14858
Pathway	REACTOME_ARACHIDONIC_ACID_METABOLISM	ABCC1 CYP4A11 PLA2G4A CYP4A22	3.07e-04	61	75	4	MM14861
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	PHKA2 CACNA1F CAMK2D CACNA1H GRIN2C VDAC1	3.65e-04	178	75	6	M2890
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	EPHB2 EPHA6 PAK3 EPHA7	3.91e-04	65	75	4	MM14911
Pathway	SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES	PAK5 PAK3 PPP1R13B PAK6	4.40e-04	67	75	4	M295
Pathway	KEGG_RENAL_CELL_CARCINOMA	PAK5 PAK3 PAK6 EPAS1	5.20e-04	70	75	4	M13266
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX	CYP4A11 PLA2G4A CYP4A22	5.84e-04	31	75	3	M39851
Pathway	WP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY	CACNA1F CAMK2D PLA2G4A VDAC1	6.42e-04	74	75	4	M48080
Pathway	WP_ALZHEIMERS_DISEASE	CACNA1F ERN1 LPL GRIN2C	6.42e-04	74	75	4	MM15962
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	CAMK2D SCN1A SCN2A	6.42e-04	32	75	3	M27455
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX	CYP4A11 PLA2G4A CYP4A22	7.04e-04	33	75	3	MM15918
Pathway	REACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS	EPHB2 EPHA6 EPHA7	7.69e-04	34	75	3	MM15025
Pathway	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	PAK5 PAK3 PAK6	8.38e-04	35	75	3	M16801
Pathway	REACTOME_ACTIVATION_OF_PUMA_AND_TRANSLOCATION_TO_MITOCHONDRIA	PPP1R13B TP53BP2	9.81e-04	9	75	2	M26946
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY	CYP4A11 CYP4A22	9.81e-04	9	75	2	M39819
Pubmed	Comparison of the physical and recombination maps of the mouse X chromosome.	GLA G6PD F9	5.82e-07	7	90	3	2571569
Pubmed	Efficient linkage of 10 loci in the proximal region of the mouse X chromosome.	GLA G6PD F9	5.82e-07	7	90	3	2110546
Pubmed	X-chromosome gene order in different Mus species crosses.	GLA G6PD F9	9.30e-07	8	90	3	3416629
Pubmed	The DNA sequence of the human X chromosome.	PHKA2 CACNA1F GPR174 GLA GPC3 STK26 PAK3 G6PD F9	1.15e-06	407	90	9	15772651
Pubmed	Multilocus molecular mapping of the mouse X chromosome.	GLA G6PD F9	1.39e-06	9	90	3	2906327
Pubmed	Linkage of a gene for neural cell adhesion molecule, L1 (CamL1) to the Rsvp region of the mouse X chromosome.	GLA G6PD F9	1.98e-06	10	90	3	1964443
Pubmed	HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.	EPHB2 EPHA6 EPHA7	1.98e-06	10	90	3	17304517
Pubmed	Competition is a driving force in topographic mapping.	EPHB2 EPHA6 EPHA7	2.72e-06	11	90	3	22065784
Pubmed	Conservation and reorganization of loci on the mammalian X chromosome: a molecular framework for the identification of homologous subchromosomal regions in man and mouse.	PHKA2 GLA G6PD	3.62e-06	12	90	3	2899541
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	FKBP10 ABCC1 GLA CAMK2D STK26 DNAH2 SCYL1 LPGAT1 LRP6 ALG1 VDAC1 CDC23	5.73e-06	942	90	12	31073040
Pubmed	Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.	CYP4A11 CYP4A22	6.62e-06	2	90	2	15611369
Pubmed	Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits.	GABBR2 GABBR1	6.62e-06	2	90	2	15706241
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	6.62e-06	2	90	2	10827969
Pubmed	Characterization of GABAB receptor in the human colon.	GABBR2 GABBR1	6.62e-06	2	90	2	14978362
Pubmed	Functional expression of the GABAB receptor in human airway smooth muscle.	GABBR2 GABBR1	6.62e-06	2	90	2	16829628
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	6.62e-06	2	90	2	19694741
Pubmed	Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53.	PPP1R13B TP53BP2	6.62e-06	2	90	2	15757645
Pubmed	Expression of GABA(B) receptors is altered in brains of subjects with autism.	GABBR2 GABBR1	6.62e-06	2	90	2	19002745
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	6.62e-06	2	90	2	1317301
Pubmed	Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.	CYP4A11 CYP4A22	6.62e-06	2	90	2	23641057
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	6.62e-06	2	90	2	31439038
Pubmed	Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.	GABBR2 GABBR1	6.62e-06	2	90	2	15240800
Pubmed	The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.	CYP4A11 CYP4A22	6.62e-06	2	90	2	28912346
Pubmed	Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations.	GABBR2 GABBR1	6.62e-06	2	90	2	19763258
Pubmed	Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.	CYP4A11 CYP4A22	6.62e-06	2	90	2	24413902
Pubmed	DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation.	DOCK2 DOCK5	6.62e-06	2	90	2	25339677
Pubmed	Heterodimerization is required for the formation of a functional GABA(B) receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	9872316
Pubmed	GABA(B)-receptor subtypes assemble into functional heteromeric complexes.	GABBR2 GABBR1	6.62e-06	2	90	2	9872317
Pubmed	Osteoblastic γ-aminobutyric acid, type B receptors negatively regulate osteoblastogenesis toward disturbance of osteoclastogenesis mediated by receptor activator of nuclear factor κB ligand in mouse bone.	GABBR2 GABBR1	6.62e-06	2	90	2	21828041
Pubmed	[Promoter methylation of ASPP1 and ASPP2 genes in non-small cell lung cancers].	PPP1R13B TP53BP2	6.62e-06	2	90	2	22169642
Pubmed	Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.	CYP4A11 CYP4A22	6.62e-06	2	90	2	8031839
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	6.62e-06	2	90	2	15249644
Pubmed	GABAergic input through GABAB receptors is necessary during a perinatal window to shape gene expression of factors critical to reproduction such as Kiss1.	GABBR2 GABBR1	6.62e-06	2	90	2	32286880
Pubmed	Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.	CYP4A11 CYP4A22	6.62e-06	2	90	2	10860550
Pubmed	Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma.	PPP1R13B TP53BP2	6.62e-06	2	90	2	20034025
Pubmed	Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	10773016
Pubmed	Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.	CYP4A11 CYP4A22	6.62e-06	2	90	2	11320253
Pubmed	Developing oligodendrocytes express functional GABA(B) receptors that stimulate cell proliferation and migration.	GABBR2 GABBR1	6.62e-06	2	90	2	17144904
Pubmed	Molecular identification of the human GABABR2: cell surface expression and coupling to adenylyl cyclase in the absence of GABABR1.	GABBR2 GABBR1	6.62e-06	2	90	2	10328880
Pubmed	Characterization of the CYP4A11 gene, a second CYP4A gene in humans.	CYP4A11 CYP4A22	6.62e-06	2	90	2	12464262
Pubmed	ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.	PPP1R13B TP53BP2	6.62e-06	2	90	2	26595804
Pubmed	Structural Basis for Activation of the Heterodimeric GABAB Receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	33058878
Pubmed	Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation.	GABBR2 GABBR1	6.62e-06	2	90	2	20962240
Pubmed	Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.	CYP4A11 CYP4A22	6.62e-06	2	90	2	15066132
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	6.62e-06	2	90	2	30693367
Pubmed	Profiling of GABAA and GABAB receptor expression in the myometrium of the human uterus.	GABBR2 GABBR1	6.62e-06	2	90	2	30343129
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	6.62e-06	2	90	2	29649454
Pubmed	Deficits in GABA(B) receptor system in schizophrenia and mood disorders: a postmortem study.	GABBR2 GABBR1	6.62e-06	2	90	2	21303731
Pubmed	Structure of human GABAB receptor in an inactive state.	GABBR2 GABBR1	6.62e-06	2	90	2	32581365
Pubmed	20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.	CYP4A11 CYP4A22	6.62e-06	2	90	2	23825080
Pubmed	Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2.	GABBR2 GABBR1	6.62e-06	2	90	2	22660477
Pubmed	Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.	CYP4A11 CYP4A22	6.62e-06	2	90	2	16691295
Pubmed	The P450 gene superfamily: recommended nomenclature.	CYP4A11 CYP4A22	6.62e-06	2	90	2	3829886
Pubmed	Independent maturation of the GABA(B) receptor subunits GABA(B1) and GABA(B2) during postnatal development in rodent brain.	GABBR2 GABBR1	6.62e-06	2	90	2	15305362
Pubmed	Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity.	GABBR2 GABBR1	6.62e-06	2	90	2	10075644
Pubmed	Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.	CYP4A11 CYP4A22	6.62e-06	2	90	2	29277328
Pubmed	Structural basis of the activation of a metabotropic GABA receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	32555460
Pubmed	A transcriptional study in mice with different ethanol-drinking profiles: possible involvement of the GABA(B) receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	22579910
Pubmed	Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.	CYP4A11 CYP4A22	6.62e-06	2	90	2	21820496
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	6.62e-06	2	90	2	33096315
Pubmed	Structures of metabotropic GABAB receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	32580208
Pubmed	GABAB receptors in Schwann cells influence proliferation and myelin protein expression.	GABBR2 GABBR1	6.62e-06	2	90	2	15147298
Pubmed	Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded.	GABBR2 GABBR1	6.62e-06	2	90	2	15304491
Pubmed	Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.	CYP4A11 CYP4A22	6.62e-06	2	90	2	20943934
Pubmed	The Sushi domains of GABAB receptors function as axonal targeting signals.	GABBR2 GABBR1	6.62e-06	2	90	2	20107064
Pubmed	Heterodimeric coiled-coil interactions of human GABAB receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	24778228
Pubmed	GABAB receptors are expressed in human aortic smooth muscle cells and regulate the intracellular Ca(2+) concentration.	GABBR2 GABBR1	6.62e-06	2	90	2	24682435
Pubmed	Apoptosis stimulating protein of p53 (ASPP) 1 and ASPP2 m-RNA expression in oral cancer.	PPP1R13B TP53BP2	6.62e-06	2	90	2	32987288
Pubmed	The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.	CYP4A11 CYP4A22	6.62e-06	2	90	2	2766933
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	6.62e-06	2	90	2	26311622
Pubmed	Structural mechanism of ligand activation in human GABA(B) receptor.	GABBR2 GABBR1	6.62e-06	2	90	2	24305054
Pubmed	Alcohol use disorder and GABAB receptor gene polymorphisms in an Italian sample: haplotype frequencies, linkage disequilibrium and association studies.	GABBR2 GABBR1	6.62e-06	2	90	2	28118741
Pubmed	A novel GLA mutation in a Fabry family with glucose-6-phosphate dehydrogenase deficiency.	GLA G6PD	6.62e-06	2	90	2	22307442
Pubmed	[Methylation of phenols using metal-salt catalysts (author's transl)].	GABBR2 GABBR1	6.62e-06	2	90	2	987231
Pubmed	Increased expression of gamma-aminobutyric acid type B receptors in the hippocampus of patients with temporal lobe epilepsy.	GABBR2 GABBR1	6.62e-06	2	90	2	14625043
Pubmed	Roles of GABAB receptor subtypes in presynaptic auto- and heteroreceptor function regulating GABA and glutamate release.	GABBR2 GABBR1	6.62e-06	2	90	2	18665320
Pubmed	ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells.	PPP1R13B TP53BP2	6.62e-06	2	90	2	23392125
Pubmed	The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.	SCN1A SCN2A	6.62e-06	2	90	2	21377452
Pubmed	Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.	CYP4A11 CYP4A22	6.62e-06	2	90	2	17112342
Pubmed	Gradual downregulation of protein expression of the partner GABA(B)R2 subunit during postnatal brain development in mice defective of GABA(B)R1 subunit.	GABBR2 GABBR1	6.62e-06	2	90	2	21160134
Pubmed	High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.	CYP4A11 CYP4A22	6.62e-06	2	90	2	30088983
Pubmed	Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.	CYP4A11 CYP4A22	6.62e-06	2	90	2	19208908
Pubmed	Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.	EPHB2 EPHA6 EPHA7	9.16e-06	16	90	3	8755474
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB2 EPHA6 EPHA7	1.11e-05	17	90	3	12217323
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHB2 EPHA6 EPHA7	1.58e-05	19	90	3	12684176
Pubmed	Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice.	PAK5 PAK6	1.98e-05	3	90	2	23593460
Pubmed	Prognostic significance of PAK family kinases in acute myeloid leukemia.	PAK5 PAK3	1.98e-05	3	90	2	30890765
Pubmed	G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.	GRK5 LRP6	1.98e-05	3	90	2	19801552
Pubmed	Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.	SCN1A SCN2A	1.98e-05	3	90	2	32185219
Pubmed	Post-endocytotic Deubiquitination and Degradation of the Metabotropic γ-Aminobutyric Acid Receptor by the Ubiquitin-specific Protease 14.	GABBR2 GABBR1	1.98e-05	3	90	2	26817839
Pubmed	Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice.	CYP4A11 CYP4A22	1.98e-05	3	90	2	2354437
Pubmed	Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.	SCN1A SCN2A	1.98e-05	3	90	2	32005694
Pubmed	ASPP: a new family of oncogenes and tumour suppressor genes.	PPP1R13B TP53BP2	1.98e-05	3	90	2	17211478
Pubmed	Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.	GABBR2 GABBR1	1.98e-05	3	90	2	15660124
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A	1.98e-05	3	90	2	23859570
Pubmed	Puerarin alleviates noise-induced hearing loss via affecting PKCγ and GABAB receptor expression.	GABBR2 GABBR1	1.98e-05	3	90	2	25592416
Pubmed	Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors.	GABBR2 GABBR1	1.98e-05	3	90	2	16081421
Pubmed	Differential sensitivity of Pak5, Pak6, and Pak5/Pak6 double-knockout mice to the stimulant effects of amphetamine and exercise-induced alterations in body weight.	PAK5 PAK6	1.98e-05	3	90	2	23710594
Pubmed	Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.	CYP4A11 CYP4A22	1.98e-05	3	90	2	28270609
Pubmed	Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons.	GABBR2 GABBR1	1.98e-05	3	90	2	17591780
Cytoband	8q24.12	TAF2 DSCC1	2.92e-04	13	90	2	8q24.12
Cytoband	2q24.3	SCN1A SCN2A	4.48e-04	16	90	2	2q24.3
GeneFamily	Gamma-aminobutyric acid type B receptor subunits\|Sushi domain containing	GABBR2 GABBR1	1.35e-05	2	67	2	280
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB2 EPHA6 EPHA7	1.72e-05	14	67	3	1095
GeneFamily	Sterile alpha motif domain containing	EPHB2 EPHA6 CASKIN1 EPHA7	3.18e-04	88	67	4	760
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A	4.79e-04	9	67	2	1203
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL9 OSBP2	8.72e-04	12	67	2	670
GeneFamily	Dyneins, axonemal	DNAH2 DNAH5	1.77e-03	17	67	2	536
GeneFamily	FKBP prolyl isomerases	FKBP10 FKBP5	1.99e-03	18	67	2	910
GeneFamily	Ankyrin repeat domain containing	ANKUB1 CASKIN1 ANKDD1B PPP1R13B TP53BP2	2.03e-03	242	67	5	403
GeneFamily	Calcium voltage-gated channel subunits	CACNA1F CACNA1H	4.15e-03	26	67	2	253
GeneFamily	Cytochrome P450 family 4	CYP4A11 CYP4A22	7.86e-03	36	67	2	1003
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	SH3TC1 FKBP5 CDC23	8.94e-03	115	67	3	769
Coexpression	GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN	DOCK2 BMPR2 GRK5 SCYL1 LPGAT1 FRYL FKBP5	5.50e-06	200	89	7	M9321
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	GPC3 STK26 GRK5 LPL PAK3 PPP1R13B PLA2G4A CACNA1H G6PD ANGPTL1 OLFML3 FKBP5 EPHA7	2.06e-05	768	90	13	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	GPC3 STK26 GRK5 NTNG1 PAK3 PPP1R13B PLA2G4A CACNA1H DSCC1 G6PD OLFML3 FKBP5 EPHA7	2.88e-05	793	90	13	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	GPC3 STK26 GRK5 PAK3 PPP1R13B PLA2G4A OLFML3 FKBP5 EPHA7	2.92e-05	373	90	9	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000	GPR50 ABCA5 CAMK2D SCN1A SCN2A LPL SOCS4 NTNG1 LRP6 PLA2G4A OLFML3 CDC23 SULT1E1	4.02e-05	819	90	13	gudmap_developingKidney_e15.5_Peripheral blastema_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	GPC3 STK26 GRK5 SCN2A LPL PLA2G4A OLFML3 FKBP5 EPHA7	7.04e-05	418	90	9	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	GPC3 GRK5 SCN2A NTNG1 PAK3 PLA2G4A CACNA1H G6PD ANGPTL1 OLFML3 FKBP5 EPHA7	1.01e-04	773	90	12	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	GPC3 STK26 GRK5 NTNG1 PAK3 PPP1R13B PLA2G4A CACNA1H DSCC1 OLFML3 FKBP5 EPHA7	1.06e-04	777	90	12	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	BM Top 100 - thalamus	SCN1A SCN2A NTNG1 GABBR2	1.40e-04	62	90	4	BM Top 100 - thalamus
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	GPC3 STK26 GRK5 PAK3 PLA2G4A OLFML3 FKBP5 EPHA7	1.58e-04	364	90	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	LPL PAK3 G6PD ANGPTL1 OLFML3 FKBP5	1.63e-04	191	90	6	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	ALKBH8 GLA GPC3 STK26 GRK5 SCN2A LPL PPP1R13B PLA2G4A OLFML3 FKBP5 EPHA7	1.89e-04	827	90	12	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	GLA GPC3 STK26 GRK5 LPL PAK3 PPP1R13B PLA2G4A DSCC1 OLFML3 FKBP5 EPHA7	2.41e-04	849	90	12	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#4	BMPR2 STK26 DNAH2 NTNG1 LPGAT1 PLA2G4A ATP5MJ ANGPTL1 OLFML3 EPAS1 EPHA7	2.62e-04	731	90	11	Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K4
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000	GLA GPC3 ERN1 STK26 GRK5 LPL PLA2G4A KCNG3 DSCC1 OLFML3 FKBP5 EPHA7	2.65e-04	858	90	12	gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	DOCK2 ERN1 STK26 GRK5 SCN2A CASP6 PLA2G4A KCNG3 OLFML3 FKBP5 EPHA7	2.91e-04	740	90	11	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200	GPC3 GRK5 PAK3 PLA2G4A OLFML3	3.04e-04	138	90	5	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	PAK3 G6PD ANGPTL1 OLFML3 FKBP5	3.04e-04	138	90	5	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_1000
CoexpressionAtlas	NK cells, NK.Sp, NK1.1+, Spleen, avg-3	DOCK2 DOCK5 GPR174 ERN1 CORO2A GRK5 KCNK5 FRYL	3.46e-04	409	90	8	GSM538315_500
CoexpressionAtlas	NK cells, NK.H+.MCMV7.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3	DOCK2 DOCK5 GPR174 ERN1 CORO2A GRK5 KCNK5 FRYL	3.69e-04	413	90	8	GSM538303_500
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_500	GPR50 ABCA5 SCN1A LPL SOCS4 NTNG1 CDC23 SULT1E1	4.19e-04	421	90	8	gudmap_developingKidney_e15.5_Peripheral blastema_500
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_1000	GPR50 CAMK2D SCN1A LPL OLFML3 SULT1E1	4.84e-04	234	90	6	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k2
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	STK26 GRK5 PAK3 PLA2G4A OLFML3	4.89e-04	153	90	5	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 DOCK5 STK10 KLHL2 SH3TC1 PLA2G4A FKBP5	1.69e-07	200	90	7	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	facs-Large_Intestine-Proximal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A TMPRSS6 LPL ACSF2 LARS2 FKBP5	1.19e-06	168	90	6	23e0e1592d7400012d289adb10c7598285bae2e9
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK2 EPM2A CORO2A LPL FKBP5 SULT1E1	1.19e-06	168	90	6	a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	DNAH2 KCNK5 PAK3 FKBP5 GABBR1 CDC23	1.23e-06	169	90	6	625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A TMPRSS6 LPL ACSF2 LARS2 FKBP5	1.41e-06	173	90	6	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A TMPRSS6 LPL ACSF2 LARS2 FKBP5	1.41e-06	173	90	6	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GPC3 ERN1 CYP4A11 TMPRSS6 KLKB1 FKBP5	2.58e-06	192	90	6	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	FKBP10 GPC3 LPL NTNG1 OLFML3 SULT1E1	2.74e-06	194	90	6	8fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 DOCK5 STK10 KLHL2 SH3TC1 FKBP5	2.91e-06	196	90	6	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GPC3 GRK5 LPL NTNG1 OLFML3 SULT1E1	2.99e-06	197	90	6	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GPC3 GRK5 LPL NTNG1 OLFML3 SULT1E1	2.99e-06	197	90	6	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA5 SCN1A SCN2A PAK5 PAK3 GABBR2	3.08e-06	198	90	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA5 SCN1A SCN2A PAK5 PAK3 GABBR2	3.08e-06	198	90	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA5 SCN1A SCN2A PAK5 PAK3 GABBR2	3.08e-06	198	90	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Control_saline-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|Control_saline / Treatment groups by lineage, cell group, cell type	DOCK2 DOCK5 GLA ENTPD3 CHIT1 G6PD	3.17e-06	199	90	6	e1240bfcdce76ec018599c50350748f9c7b8fb0e
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPHB2 DOCK2 ABCC1 ERN1 RNFT2	1.18e-05	146	90	5	b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCell	LPS-antiTNF-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 GPR174 STK26 PAK3 GABBR2	1.22e-05	147	90	5	1ecd7c084e73eb6fae1ab1f9aae17115d3d62cbd
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA5 CASKIN1 STK26 GRK5 NTNG1	1.58e-05	155	90	5	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	Control-Myeloid-Monocytes,_Macrophages-Mast-cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK5 GPR174 STK26 PAK3 PLA2G4A	1.79e-05	159	90	5	81782e9e370558d61af5e0c760ac9759d69fb725
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHA6 ABCA5 ANKUB1 LARS2 KLKB1	1.95e-05	162	90	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 STK10 ABCC1 LPL GABBR1	2.01e-05	163	90	5	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 STK10 ABCC1 LPL GABBR1	2.01e-05	163	90	5	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ABCC1 GPC3 PAK5 ENTPD3 G6PD	2.07e-05	164	90	5	81c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ABCC1 GLA LPL PLA2G4A	2.33e-05	168	90	5	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ABCC1 GLA LPL PLA2G4A	2.33e-05	168	90	5	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 CORO2A LPL VPS50 FKBP5	2.39e-05	169	90	5	305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK5 CORO2A SCN1A PAK5 OSBP2	2.99e-05	177	90	5	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DOCK5 CORO2A SCN1A PAK5 OSBP2	2.99e-05	177	90	5	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPM2A ABCA5 STK26 LPGAT1 GABBR2	3.07e-05	178	90	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ABCC1 GPC3 NTNG1 ANGPTL1 SULT1E1	3.15e-05	179	90	5	c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A ATP5MJ ACSF2 LARS2 FKBP5	3.32e-05	181	90	5	a52e367f0909689174b3534f0cd51f36abe1b49f
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DOCK2 DNAH5 ANGPTL1 F9	3.35e-05	90	90	4	3817a5b0235e632d976ea565175bdbebbd959bf0
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DOCK2 DNAH5 ANGPTL1 F9	3.35e-05	90	90	4	a528f5dcee1a356dea89ff2588d2e0f276f2d5fc
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCN2A PAK5 ENTPD3 NTNG1 GABBR2	3.78e-05	186	90	5	18fd311252299d6d30ddb32002ed069056108206
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHKA2 SH3TC1 LPL ALG3 EPAS1	3.88e-05	187	90	5	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHKA2 SH3TC1 LPL ALG3 EPAS1	3.88e-05	187	90	5	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK5 GRK5 PLA2G4A KCNG3 FKBP5	4.40e-05	192	90	5	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 LPL PPP1R13B LARS2 EPAS1	4.40e-05	192	90	5	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ENTPD3 OSBPL9 CACNA1H EPAS1 SULT1E1	4.40e-05	192	90	5	5995bae840c0b3f420288f557634d0ae9a12a6ae
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GPC3 LPL NTNG1 OLFML3 SULT1E1	4.62e-05	194	90	5	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GPC3 GRK5 LPL OLFML3 SULT1E1	4.62e-05	194	90	5	99577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCell	Control-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	FKBP10 GPC3 NTNG1 ANGPTL1 OLFML3	4.62e-05	194	90	5	3c2266772c5b56e8e02a461e5193e29588028ee9
ToppCell	21-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	FKBP10 GPC3 LPL NTNG1 OLFML3	4.62e-05	194	90	5	749dd8113ef260e00facac09de9861d61725124a
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	FKBP10 GPC3 NTNG1 ANGPTL1 OLFML3	4.74e-05	195	90	5	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GPC3 GRK5 LPL OLFML3 SULT1E1	4.74e-05	195	90	5	70387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell	Control-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	ABCC1 ERN1 SH3TC1 CAMK2D FKBP5	4.74e-05	195	90	5	6687e579582d7a239bee80846de0cf827a6f6a62
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA5 SCN2A PAK5 PAK3 GABBR2	4.85e-05	196	90	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GPC3 GRK5 NTNG1 OLFML3 SULT1E1	4.85e-05	196	90	5	22538376a95fe3afe8639a216a5497087aa94110
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GPC3 GRK5 PAK5 ANGPTL1 SULT1E1	4.85e-05	196	90	5	ee45e4de9d706ec87094e87f47d3e514539b8092
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	ABCC1 ERN1 SH3TC1 FKBP5 TP53BP2	4.85e-05	196	90	5	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GPC3 GRK5 PAK5 ANGPTL1 SULT1E1	4.85e-05	196	90	5	fa4a85a3cd52df0da5dfedc0e584e9df8c61ce89
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	BMPR2 GRK5 LPL FKBP5 EPAS1	4.97e-05	197	90	5	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GPC3 LPL NTNG1 OLFML3 SULT1E1	4.97e-05	197	90	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMPR2 GRK5 PLA2G4A DNAH5 EPAS1	4.97e-05	197	90	5	d9e196c8b4a6ede4733946dbdba3331534954beb
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CACNA1F ERN1 ABCA5 PLA2G4A TP53BP2	5.09e-05	198	90	5	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A PAK5 PAK3 GABBR2	5.09e-05	198	90	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GPC3 LPL NTNG1 OLFML3 SULT1E1	5.09e-05	198	90	5	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	IPF\|World / Disease state, Lineage and Cell class	LPL ATP5MJ CHIT1 DNAH5 VDAC1	5.09e-05	198	90	5	7f8734729194caccab8ec98e6c1a00ff5c3655af
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA5 SCN2A PAK5 PAK3 GABBR2	5.09e-05	198	90	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	DOCK2 DOCK5 STK10 SH3TC1 FKBP5	5.09e-05	198	90	5	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	15-Distal-Mesenchymal-Mesenchyme_RSPO2+\|Distal / Age, Tissue, Lineage and Cell class	GPC3 LPL NTNG1 OLFML3 SULT1E1	5.09e-05	198	90	5	e87d1fe2befbd32b0c723ab43b9de95495ea3ee3
ToppCell	18-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	GPC3 LPL NTNG1 OLFML3 SULT1E1	5.22e-05	199	90	5	7ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FKBP10 GPC3 ANGPTL1 OLFML3 SULT1E1	5.22e-05	199	90	5	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	18-Distal-Mesenchymal-Mesenchyme_RSPO2+\|Distal / Age, Tissue, Lineage and Cell class	GPC3 LPL NTNG1 OLFML3 SULT1E1	5.22e-05	199	90	5	95403988caef322314f4ed15415ad1a9a987adc1
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCN2A ENTPD3 GABBR2 NPAS1 EPHA7	5.34e-05	200	90	5	2f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FKBP10 GPC3 NTNG1 ANGPTL1 OLFML3	5.34e-05	200	90	5	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 NTNG1 PLA2G4A KCNG3 FREM3	5.34e-05	200	90	5	9c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCN2A ENTPD3 GABBR2 NPAS1 EPHA7	5.34e-05	200	90	5	bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell	15-Airway\|15 / Age, Tissue, Lineage and Cell class	FKBP10 GPC3 ANGPTL1 OLFML3 SULT1E1	5.34e-05	200	90	5	ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	ABCA5 SCN2A PAK5 PAK3 GABBR2	5.34e-05	200	90	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPHA6 GRIN2C KLKB1 GABBR1 TP53BP2	5.34e-05	200	90	5	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPHA6 GRIN2C KLKB1 GABBR1 TP53BP2	5.34e-05	200	90	5	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	ABCA5 SCN2A PAK5 LPGAT1 EPHA7	5.34e-05	200	90	5	f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 NTNG1 PLA2G4A KCNG3 FREM3	5.34e-05	200	90	5	8821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCell	LPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PHKA2 ABCC1 GPR174 GLA STK26	5.34e-05	200	90	5	2200a621da1634728a49b1706e422e3e78b1f3bf
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCN2A ENTPD3 GABBR2 NPAS1 EPHA7	5.34e-05	200	90	5	dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 NTNG1 PLA2G4A KCNG3 FREM3	5.34e-05	200	90	5	96b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCell	wk_20-22-Mesenchymal-Fibroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FKBP10 GPC3 NTNG1 OLFML3 SULT1E1	5.34e-05	200	90	5	94bd00fb6ff0dcb668eb36ec2085f1c3128855b6
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPHA6 GRIN2C KLKB1 GABBR1 TP53BP2	5.34e-05	200	90	5	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 NTNG1 PLA2G4A KCNG3 FREM3	5.34e-05	200	90	5	ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK5 CORO2A PAK5 OSBP2	6.60e-05	107	90	4	410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK5 CORO2A PAK5 OSBP2	6.60e-05	107	90	4	5bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	EPHA6 NTNG1 A4GNT CACNA1H	7.61e-05	111	90	4	1847dde68d349114286bc3317be6339666df4aa2
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	DOCK5 ANKUB1 KCNK5 DENND5A	1.36e-04	129	90	4	b3cb0c10659d1216b8f7de3aa1f9aac101cb65dd
ToppCell	Severe-B_intermediate-14\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DOCK5 GPR174 ANKDD1B DENND5A	1.97e-04	142	90	4	f9cbc266fcea19bec504be4f3a28d1173c6b2e3c
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	EPHA6 NTNG1 CACNA1H KCNG3	2.02e-04	143	90	4	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EPM2A ALKBH8 CHIT1 KLKB1	2.08e-04	144	90	4	5e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCell	LPS-antiTNF-Hematopoietic_Mast-Mast_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 GPR174 PAK3 GABBR2	2.37e-04	149	90	4	59aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCell	remission-multiplets\|remission / disease stage, cell group and cell class	CACNA1F CASKIN1 CHIT1 TP53BP2	2.37e-04	149	90	4	e9974260a5f2999b363f306cae005698c912893a
ToppCell	LPS-antiTNF-Hematopoietic_Mast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 GPR174 PAK3 GABBR2	2.37e-04	149	90	4	1527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 STK26 PAK3 GABBR2	2.43e-04	150	90	4	ccb782fbcb3122266354a112a9a850506664f44d
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SH3TC1 SOCS4 FRYL OLFML3	2.43e-04	150	90	4	744050a1b665c6989f37141348af3df7579a73c9
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK2 GPR174 PAK3 GABBR2	2.49e-04	151	90	4	b85a763459a0f019d1f9975d09b9f2247d62c9d3
ToppCell	COVID-19_Mild-PLT_0\|World / Disease Group and Platelet Clusters	DOCK5 PTPA SCN1A ATP5MJ	2.55e-04	152	90	4	d49f7c0681500fc4d93818d47e8e8afb726c23d9
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK5 ABCA5 CORO2A FREM3	2.68e-04	154	90	4	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK5 ABCA5 CORO2A FREM3	2.68e-04	154	90	4	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCN1A SCN2A NTNG1 GABBR1	2.75e-04	155	90	4	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERN1 CORO2A PLA2G4A FKBP5	2.82e-04	156	90	4	8349604bd801e20d33770f7d8243598c3756302b
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KCNK5 PAK6 GABBR2 LARS2	2.89e-04	157	90	4	4766f7d545bf2d775390589460677519cb92f4d5
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TMEM249 TMPRSS6 PAK3 DNAH5	2.96e-04	158	90	4	3bc51cfd37b289cc3e866b54ce55a298e5eff690
Drug	hydroxyl radicals	TYR DOCK5 ABCC1 EFL1 PTPA EPM2A GLA CYP4A11 LPL ENTPD3 PPP1R13B LRP6 PLA2G4A CHIT1 G6PD ENOPH1 F9 CDC23 CYP4A22	9.85e-07	1341	90	19	CID000000961
Drug	Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A	EPHB2 GRK5 VPS50 ENTPD3 CACNA1H LARS2 ZNF446 NPAS1	1.20e-06	198	90	8	7357_UP
Drug	3,5-di-tert-butylcatechol	TYR SCN2A DNAH5 TP53BP2	1.30e-06	21	90	4	CID000066099
Drug	NSC618487	STK10 PTPA EPHA6 ERN1 CAMK2D LPL PAK5 ENTPD3 PAK3 CASP6 PLA2G4A GRIN2C PAK6 VDAC1 EPHA7	3.57e-06	933	90	15	CID000005279
Drug	gb1a	TYR GABBR2 GABBR1	4.93e-06	9	90	3	CID000467746
Drug	sunitinib	STK10 EPM2A EPHA6 CAMK2D ALG1 EPHA7	1.30e-05	130	90	6	CID005329102
Drug	2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol	GABBR2 GABBR1	1.55e-05	2	90	2	ctd:C438607
Drug	Baclofen	GABBR2 GABBR1	1.55e-05	2	90	2	DB00181
Drug	CGP 71872	GABBR2 GABBR1	1.55e-05	2	90	2	ctd:C104980
Drug	CGP 55845A	GABBR2 GABBR1	1.55e-05	2	90	2	ctd:C085075
Drug	3-aminopropylphosphinic acid	GABBR2 GABBR1	1.55e-05	2	90	2	ctd:C061388
Drug	NSC227243	TYR GLA SCN2A	2.11e-05	14	90	3	CID000024346
Drug	Zonisamide	SCN1A SCN2A CACNA1H	3.90e-05	17	90	3	DB00909
Drug	vandetanib	STK10 EPM2A GLA EPHA6 EPHA7	4.61e-05	99	90	5	CID003081361
Drug	GW 7845	CAMK2D LPL CASP6	4.67e-05	18	90	3	ctd:C401311
Disease	Bipolar Disorder	PTPA GPR50 SCN2A NTNG1 PLA2G4A LARS2 G6PD F9 FKBP5	1.42e-05	477	89	9	C0005586
Disease	Nonorganic psychosis	TYR PAK5 FKBP5 NPAS1	5.76e-05	69	89	4	C0349204
Disease	level of lipoprotein lipase in blood serum	LPL KLKB1	8.94e-05	5	89	2	OBA_2042223
Disease	Cerebral Small Vessel Diseases	GLA SCN1A	8.94e-05	5	89	2	C2733158
Disease	Rett Syndrome, Atypical	NTNG1 GABBR2	8.94e-05	5	89	2	C2748910
Disease	atopy	PAK5 PAK6	8.94e-05	5	89	2	EFO_0002686
Disease	Epilepsy, Cryptogenic	ERN1 SCN1A SCN2A VDAC1	1.13e-04	82	89	4	C0086237
Disease	Awakening Epilepsy	ERN1 SCN1A SCN2A VDAC1	1.13e-04	82	89	4	C0751111
Disease	Aura	ERN1 SCN1A SCN2A VDAC1	1.13e-04	82	89	4	C0236018
Disease	congenital disorder of glycosylation (implicated_via_orthology)	ALG3 ALG1	1.34e-04	6	89	2	DOID:5212 (implicated_via_orthology)
Disease	Epilepsy, Generalized	SCN1A CACNA1H	1.34e-04	6	89	2	C0014548
Disease	X-14939 measurement	CYP4A11 CYP4A22	1.34e-04	6	89	2	EFO_0800747
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	1.87e-04	7	89	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	1.87e-04	7	89	2	C0751057
Disease	disease recurrence, response to allogeneic hematopoietic stem cell transplant, donor genotype effect measurement	PAK5 PAK6	1.87e-04	7	89	2	EFO_0004952, EFO_0007044, EFO_0007892
Disease	Psychotic Disorders	TYR PAK5 FKBP5 NPAS1	2.53e-04	101	89	4	C0033975
Disease	Febrile Convulsions	SCN1A SCN2A	3.19e-04	9	89	2	C0009952
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	3.19e-04	9	89	2	C3502809
Disease	Schizophrenia	TYR CACNA1F GPR50 LPL NTNG1 PLA2G4A GRIN2C LARS2 GABBR1 NPAS1	3.29e-04	883	89	10	C0036341
Disease	Epilepsy	ERN1 SCN1A SCN2A VDAC1	3.38e-04	109	89	4	C0014544
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A	3.98e-04	10	89	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A	3.98e-04	10	89	2	DOID:0080422 (implicated_via_orthology)
Disease	myelodysplastic syndrome	PLA2G4A TAF2	3.98e-04	10	89	2	EFO_0000198
Disease	Pulmonary arterial hypertension	BMPR2 EPAS1	3.98e-04	10	89	2	C2973725
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	CYP4A11 CYP4A22	4.86e-04	11	89	2	DOID:0110861 (biomarker_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A	5.82e-04	12	89	2	DOID:0060170 (implicated_via_orthology)
Disease	Metastatic melanoma	PAK5 SCYL1 EPHA7	5.89e-04	54	89	3	C0278883
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	6.87e-04	13	89	2	C0751122
Disease	MMR-related febrile seizures	SCN1A SCN2A	9.21e-04	15	89	2	EFO_0006519
Disease	P wave duration	CAMK2D EPAS1	9.21e-04	15	89	2	EFO_0005094
Disease	Idiopathic pulmonary arterial hypertension	BMPR2 EPAS1	1.05e-03	16	89	2	C3203102
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	1.05e-03	16	89	2	C0393706
Disease	succinylcarnitine measurement	ABCC1 PTPA	1.05e-03	16	89	2	EFO_0020020
Disease	sphingomyelin 14:0 measurement	PAK5 PAK6	1.19e-03	17	89	2	EFO_0010390
Disease	diet measurement	TYR PTPA ANKUB1 SCN2A KCNK5 CACNA1H ATP5MJ LARS2 DNAH5 EPHA7	1.24e-03	1049	89	10	EFO_0008111
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	1.33e-03	18	89	2	HP_0002373
Disease	polycystic kidney disease (biomarker_via_orthology)	PLA2G4A EPAS1	1.49e-03	19	89	2	DOID:0080322 (biomarker_via_orthology)
Disease	epilepsy (implicated_via_orthology)	CAMK2D SCN1A SCN2A GRIN2C	1.52e-03	163	89	4	DOID:1826 (implicated_via_orthology)
Disease	coagulation factor V measurement	PAK5 PAK6	1.65e-03	20	89	2	EFO_0008087
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A	2.00e-03	22	89	2	DOID:2030 (implicated_via_orthology)
Disease	Drug toxicity	ABCC1 CACNA1H EPHA7	2.12e-03	84	89	3	C0013221
Disease	Adverse reaction to drug	ABCC1 CACNA1H EPHA7	2.12e-03	84	89	3	C0041755
Disease	Involutional paraphrenia	FREM3 FKBP5	2.58e-03	25	89	2	C1571983
Disease	Psychosis, Involutional	FREM3 FKBP5	2.58e-03	25	89	2	C1571984
Disease	Involutional Depression	FREM3 FKBP5	2.58e-03	25	89	2	C0011574
Disease	triacylglycerol 56:5 measurement	DOCK5 LPL	2.79e-03	26	89	2	EFO_0010432
Disease	Glycogen Storage Disease	PHKA2 EPM2A	3.01e-03	27	89	2	C0017919

Protein segments in the cluster

Peptide	Gene	Start	Entry
IIGKSYDYGIDMWSV	PRPF4B	861	Q13523
ALVLGYEGWLAGYQM	VDAC1	141	P21796
KSKWGIGYRLSMYID	ABCA5	701	Q8WWZ7
QYRMLAKHGGYVWLE	EPAS1	306	Q99814
AWYGLGQTYEILKMP	CDC23	401	Q9UJX2
YWRAYAVGDVEKMAL	CDC23	456	Q9UJX2
KLVIDWHNYGYSIMG	ALG1	151	Q9BT22
GGKALIYVWAMEQEY	ALKBH8	496	Q96BT7
YTEIDWKAYMAEVEG	ALG3	66	Q92685
EVLMKTLWGDYYINM	EFL1	261	Q7Z2Z2
AIIWKYGGIYMDTDV	A4GNT	156	Q9UNA3
WGGKVRVQLYDPDYM	CYP4A11	91	Q02928
MVSEGWKDAGYEYLC	GLA	76	P06280
YCVMLGYWGEPQKTE	ACSF2	466	Q96CM8
DGEYWLGLENIYMLS	ANGPTL1	346	O95841
LGVMNKGVAYALWDY	PPP1R13B	1016	Q96KQ4
IMNKGVIYALWDYEP	TP53BP2	1056	Q13625
EEGVYGWITANYLMG	ENTPD3	181	O75355
MKRVGFQYEGTYKWV	G6PD	496	P11413
AWDDGYQIVYKLEMR	OLFML3	386	Q9NRN5
DLLDKGQVMTGYYRW	NPAS1	356	Q99742
IEGEWNGVMYAKYAT	OSBPL9	621	Q96SU4
NEMIYWGLEGAHLEY	KCNG3	96	Q8TAE7
KEGGMLAYYEVCSWK	CHIT1	296	Q13231
VVDMYSSYLVGDELW	PAK5	506	Q9P286
EDWNVVMYDGIMAYG	CACNA1F	711	O60840
YGKIVSWLEMEYGLS	FKBP5	291	Q13451
SYLVGDELWVVMEYL	PAK3	346	O75914
LAVWLSMIGLAQYYK	CASKIN1	546	Q8WXD9
YFALMDGKVYDITEW	DNAJC14	586	Q6Y2X3
EMYKSYLVGEELWVL	PAK6	466	Q9NQU5
TMIKLYREEGLAYIW	EPM2A	216	O95278
YIEGIMYKWLLGMVA	LPGAT1	56	Q92604
MAGVVEIDKYWREYI	GPC3	286	P51654
MNTWLGIFYGYKGLL	GABBR1	766	Q9UBS5
EMAGKIPNWLYLAAY	GPR50	266	Q13585
SWYIQDLCEMLGKYG	CASP6	226	P55212
SYGIVMWEVMSYGER	EPHB2	811	P29323
VFMVTEGWNYIEGLY	KCNK5	181	O95279
GMYESWVPKLVAALY	LPL	86	P06858
WGEECAMKGKYGIYT	F9	431	P00740
YMTAKYGDELAWSEV	FRYL	1371	O94915
YPEGMAVDWLGKNLY	LRP6	706	O75581
GNILALWVFYGYMKE	GPR174	36	Q9BXC1
SYGIVMWEVMSYGER	EPHA7	821	Q15375
EMACVYKGGYWEAKE	OSBP2	891	Q969R2
KWREAGMKVYIYSSG	ENOPH1	141	Q9UHY7
YDTYVGSGWLIKGMD	FKBP10	201	Q96AY3
IGGYWRILEFDYEMK	DSCC1	191	Q9BVC3
YETIIGYFDKGKMWE	DOCK2	1281	Q92608
IGDTVHILEMYEGWY	DOCK5	31	Q9H7D0
LYMGKKQDIWYVIDL	ERN1	116	O75460
WGGKVRVQLYDPDYM	CYP4A22	91	Q5TCH4
AGYDYKVMIWNLDTK	CORO2A	151	Q92828
LKQVDMYALGLIYWE	BMPR2	401	Q13873
DNSGLYAKWLVEYVM	DENND5A	1016	Q6IQ26
THMTIWLGIVYAYKG	GABBR2	651	O75899
WLGIVYAYKGLLMLF	GABBR2	656	O75899
EQPGVYTKVAEYMDW	KLKB1	606	P03952
YYTKVYQEIWIGMGL	ATP5MJ	16	P56378
LMEWLKSTDYGKYEG	EXOC1	391	Q9NV70
PDYWGLGCLIYEMIE	GRK5	366	P34947
TLEGWVDIMYYVMDA	CACNA1H	376	O95180
RCGMVYTDYADLGWK	DNAH2	2221	Q9P225
YGLYLEGAGWDKRNM	DNAH5	4536	Q8TE73
YGKPVDMWACGVILY	CAMK2D	191	Q13557
YIEAAYKVADYGMWE	PHKA2	171	P46019
WVEFSPYEIGMAKYG	PLA2G4A	346	P47712
SYGIVMWEVMSYGER	EPHA6	861	Q9UF33
GQVKLSVYWDYMKAI	ABCC1	956	P33527
QIYTEEGKVWDYMAC	NTNG1	36	Q9Y2I2
YMEKEGLYEKVVTEW	FREM3	631	P0C091
LVPIQLWYKYIMGDD	RNFT2	311	Q96EX2
AVADYWMPVDLYIGG	LARS2	546	Q15031
RAGEWKLGGLDYMYS	SCYL1	151	Q96KG9
YGSYLKGSKLWIIME	STK26	86	Q9P289
YIYGLWMKKTFGVNE	TAF2	376	Q6P1X5
CYWGVMDKYAAEALL	SOCS4	286	Q8WXH5
KGYYEWALLVAVEMG	SH3TC1	966	Q8TE82
YIFILEMLLKWVAYG	SCN1A	1261	P35498
LVVGMLIKAERYYAW	ANKDD1B	381	A6NHY2
YLELMYAGAALKDSW	ANKUB1	46	A6NFN9
YWIVAGKALDYEQML	VPS50	781	Q96JG6
TWVSEIVYMIYKEGD	SULT1E1	51	P49888
MGKWKRSQAYADYIG	PTPA	36	Q15257
LLGAYYHDGKLWIMI	STK10	96	O94804
YIFILEMLLKWVAYG	SCN2A	1251	Q99250
YYVSMDALLGGSEIW	TYR	181	P14679
ELYWDAMLEKYGTVV	ZNF446	221	Q9NWS9
VFVLEYYLDTLWKGM	TMEM249	51	Q2WGJ8
LLWYFLGYKAEVMVS	TMPRSS6	71	Q8IU80
EVDGWTLRMLIDYVY	KLHL2	101	O95198
WNGMIGEVYYKRADM	GRIN2C	491	Q14957