Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainRRM_dom

NXF3 RBM44 TIA1

4.18e-03227273IPR000504
DomainSAM_1

SAMD3 BICC1

4.32e-0368272PF00536
DomainRRM

NXF3 RBM44 TIA1

4.33e-03230273PS50102
Domain-

NXF3 RBM44 TIA1

5.11e-032442733.30.70.330
DomainNucleotide-bd_a/b_plait

NXF3 RBM44 TIA1

5.96e-03258273IPR012677
DomainSAM

SAMD3 BICC1

7.14e-0388272SM00454
DomainSAM_DOMAIN

SAMD3 BICC1

8.27e-0395272PS50105
DomainSAM

SAMD3 BICC1

8.61e-0397272IPR001660
Domain-

SAMD3 BICC1

1.02e-021062721.10.150.50
DomainSAM/pointed

SAMD3 BICC1

1.23e-02117272IPR013761
PathwayKEGG_MEDICUS_REFERENCE_BLOCKING_UBIQUITINATION_OF_H2AK119_BY_CK2

YAF2 RNF2

1.38e-0412212M47943
PathwayWP_ALZHEIMERS_DISEASE

LRP1 ADAM10 ITPR2

1.73e-0474213MM15962
PathwayKEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27

YAF2 RNF2

2.19e-0415212M47973
PathwayKEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119

YAF2 RNF2

4.80e-0422212M47924
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6

YAF2 RNF2

6.21e-0425212MM15546
PathwayKEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES

YAF2 RNF2

7.25e-0427212M47941
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

YAF2 RNF2

1.15e-0334212MM15531
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6

YAF2 RNF2

1.15e-0334212M27826
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

YAF2 RNF2

1.36e-0337212M27797
Pubmed

Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.

LRP1 ADAM10

6.25e-07228227503326
Pubmed

Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor.

LRP1 ADAM10

1.87e-06328230279425
Pubmed

The mouse YAF2 gene generates two distinct transcripts and is expressed in pre-and postimplantation embryos.

YAF2 RNF2

1.87e-06328214557078
Pubmed

Association of Rex-1 to target genes supports its interaction with Polycomb function.

YAF2 RNF2

1.74e-05828221530438
Pubmed

RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression.

GREM1 RNF2

5.65e-051428226674308
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

GALNTL6 ASTN1 ITPR2

7.39e-0510128318519826
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1 TAS1R2 ITPR2

7.39e-0510128323382219
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

KIF4B MYO1C COPG1 NFAT5 ITPR2

1.30e-0462628533644029
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

YAF2 RNF2 TIA1 COPG1

2.73e-0439628426687479
Pubmed

An AUTS2-Polycomb complex activates gene expression in the CNS.

YAF2 RNF2

4.32e-043828225519132
Pubmed

PRC1 sustains the integrity of neural fate in the absence of PRC2 function.

YAF2 RNF2

4.32e-043828234994686
Pubmed

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.

YAF2 RNF2

5.03e-044128222325352
Pubmed

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.

YAF2 RNF2

5.28e-044228229028833
Pubmed

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

YAF2 RNF2

5.79e-044428227505670
Pubmed

A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.

TIA1 NFAT5

5.79e-044428232492419
Cytoband4p16.1

ZNF518B PSAPL1

1.07e-03792824p16.1
CytobandEnsembl 112 genes in cytogenetic band chr12p11

FGD4 ITPR2

1.24e-0385282chr12p11
GeneFamilySterile alpha motif domain containing

SAMD3 BICC1

4.20e-0388202760
GeneFamilyRNA binding motif containing

RBM44 TIA1

2.28e-02213202725
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 ADAM10 SPON1 BICC1

4.50e-06178284c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASTN1 GREM1 SPON1 BICC1

6.72e-061972846b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASTN1 GREM1 SPON1 BICC1

7.00e-061992849846d6a31635fde759d55674631c11ab9270a603
ToppCellMild/Remission-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TAS1R2 GALNTL6 FGD4

8.37e-051362831b3c6edcbe0eb674d2d9c838e83ebe2b93e3eec1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GALNTL6 GREM1 SPON1

9.72e-0514328324fd24846fbef049af669a57d42fcc18928d2b27
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAM10 FGD4 ITPR2

1.12e-041502836c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 FGD4 SPON1

1.43e-04163283f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASTN1 ZNF518B STPG1

1.43e-04163283953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 FGD4 SPON1

1.46e-04164283519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

GREM1 SPON1 BICC1

1.56e-04168283838ce47d4958ba12047882f97925eddd02f081c7
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

GREM1 SPON1 BICC1

1.56e-04168283aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

GREM1 SPON1 BICC1

1.56e-04168283b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

SNTG2 SPON1 ITPR2

1.82e-04177283f0edf04930692418953e4f00a917257804ec0ffd
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

MYO1C SPON1 ITPR2

1.85e-04178283278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 GREM1 SPON1

1.89e-0417928368ccfe66474d049a926afc21bffa231446becc69
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

1.92e-0418028308ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

1.92e-041802839b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

1.95e-041812839e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 ADAM10 BICC1

1.95e-041812836a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 SPON1 BICC1

1.95e-04181283091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 SPON1 BICC1

1.98e-04182283ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ASTN1 NFAT5 ADAM10

2.01e-0418328389727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ASTN1 NFAT5 ADAM10

2.01e-04183283113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 ADAM10 BICC1

2.04e-04184283da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

LRP1 NFAT5 ITPR2

2.08e-041852831d874608aa2062024323512f68889219471b2f00
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAMD3 GREM1 BICC1

2.11e-04186283facc1bd8920003ad03d1893c32fc606d82b4d50a
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

NFAT5 ADAM10 ITPR2

2.11e-041862838571956890fc9894d766ba294a28e376b4aba428
ToppCellfacs-Heart-LA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.11e-04186283ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

GREM1 SPON1 BICC1

2.11e-041862836ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.14e-041872831669df899b1759c338ffce196fe009840123cfcd
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.14e-04187283f3ef3f5a761f8306edc39bf16e76e44aae6fa7f6
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 GREM1 SPON1

2.18e-04188283c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

LRP1 SPON1 BICC1

2.18e-04188283706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 FGD4 ITPR2

2.18e-04188283e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 GREM1 SPON1

2.18e-041882831cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GREM1 PSAPL1 BICC1

2.18e-04188283e82104f71bcdab7392fdb076dc3560255964fd9e
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 SPON1 BICC1

2.21e-0418928340cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.21e-04189283a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.21e-04189283e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.21e-041892832a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 SPON1 BICC1

2.21e-04189283bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAPL1 SPON1 BICC1

2.21e-04189283319e42f6e2322208de78bc666fb2c074707eb4da
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM10 SPON1 BICC1

2.25e-04190283b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ASTN1 SPON1

2.25e-041902839b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.25e-0419028396a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.25e-04190283841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ASTN1 SPON1

2.25e-04190283d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.25e-0419028345df8fee00f8949937863159d7aa042e72748d9b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.25e-04190283d60395739458d7f47a3350ade751fe3819500320
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SAMD3 SPON1

2.28e-04191283107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.28e-04191283b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 ADAM10 BICC1

2.28e-04191283d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.28e-041912836cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.28e-04191283850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.28e-0419128314057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 SAMD3 SPON1

2.28e-04191283bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.28e-041912838b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 SPON1 BICC1

2.28e-04191283997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-04192283dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-04192283162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-041922836f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 SPON1 BICC1

2.32e-0419228360b1312e84f6d6448365a952469c506c00b5fe93
ToppCellfacs-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 SPON1 BICC1

2.32e-041922838df15085b35b86f39debd933284cb703c5dd63c2
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.32e-04192283671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-041922833d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 SPON1 BICC1

2.32e-04192283de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-041922834e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ASTN1 SPON1 BICC1

2.32e-04192283e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-04192283ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 SPON1 BICC1

2.32e-0419228325492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.32e-04192283840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 SPON1 BICC1

2.32e-04192283c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-04192283f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

ASTN1 SPON1 BICC1

2.32e-04192283a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellP03-Mesenchymal-mesenchymal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 SPON1 BICC1

2.32e-04192283e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-04192283df1545670370fb1010c567cd059c2783eab315f7
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.32e-04192283deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.32e-041922835876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.35e-04193283735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.35e-04193283fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellPND28-Mesenchymal-Mesenchymal_structural|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 SPON1 BICC1

2.35e-04193283ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ASTN1 SPON1 BICC1

2.35e-041932839ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellfacs-Heart-RV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.35e-0419328376f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 SPON1 BICC1

2.35e-04193283ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.35e-04193283ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 SPON1 BICC1

2.35e-041932830f2167eef8203a5659c8c72e4e77646003d64797
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 SPON1 BICC1

2.35e-0419328330481fb01c7acf85beae10213f038da86bed6777
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.39e-0419428360622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.39e-041942836e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

GREM1 SPON1 BICC1

2.39e-0419428303a269f75a481ea54aea8e6444605db8d6df493d
ToppCelldroplet-Heart-nan-3m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.39e-04194283ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SPON1 BICC1

2.39e-0419428389b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 SPON1 BICC1

2.39e-041942838ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASTN1 PSAPL1 BICC1

2.39e-04194283421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCelldroplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.39e-04194283a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 SPON1 BICC1

2.39e-04194283ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCellfacs-Heart-LA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SPON1 BICC1

2.42e-0419528379a6e8e6de040ff07539e8901fc407363a50e355
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 SPON1 BICC1

2.42e-041952831236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 SPON1 BICC1

2.42e-041952836bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

LRP1 SPON1 BICC1

2.42e-041952836a02ebbeb3199447ddce64d92d8809436e040eba
Diseasetrimethylamine-N-oxide measurement

TAS1R2 ITPR2

6.75e-0514262EFO_0010541
Diseasehyperuricemia

ZNF518B NFAT5

3.88e-0433262EFO_0009104
Diseaseleft ventricular systolic function measurement

MYO1C SPON1

6.90e-0444262EFO_0008206
DiseaseAlzheimer's disease (biomarker_via_orthology)

LRP1 ADAM10

1.20e-0358262DOID:10652 (biomarker_via_orthology)
Diseasecleft lip

GALNTL6 GREM1 BICC1

1.95e-03284263EFO_0003959
Diseasesquamous cell lung carcinoma, family history of lung cancer

GALNTL6 SNTG2

2.55e-0385262EFO_0000708, EFO_0006953
Diseaseunipolar depression

GALNTL6 ASTN1 KIF4B SAMD3 ITPR2

3.63e-031206265EFO_0003761
Diseasecystatin C measurement

LRP1 RNF2 NFAT5

5.17e-03402263EFO_0004617
Diseaseurate measurement

LRP1 ZNF518B NFAT5 BICC1

7.38e-03895264EFO_0004531
Diseasecolorectal cancer, colorectal adenoma

LRP1 GREM1

7.90e-03152262EFO_0005406, MONDO_0005575

Protein segments in the cluster

PeptideGeneStartEntry
VCCMKKMDPSTCAST

ADAM10

596

O14672
GDLKQMMCPSKVSCA

BICC1

641

Q9H694
MMCPSKVSCAKRQTV

BICC1

646

Q9H694
AINPSAKCKTDMTVM

ASTN1

566

O14525
ADCSEAFLKMKMTFC

RAD21L1

76

Q9H4I0
DTEKDLPSMCCQKIM

RBM44

586

Q6ZP01
TTMMEACAKENCSPT

ITPR2

2446

Q14571
DTKMASNPRKCMAAS

NXF3

236

Q9H4D5
CSFCKPKKFTTMMVT

GREM1

141

O60565
SCTMNSKMMPECQCP

LRP1

4386

Q07954
EVTMCMKCKEPFNAL

FGD4

561

Q96M96
CSFEEAMKAMKTTGC

NFAT5

566

O94916
MGAMAKPDCIITCDS

FABP5P3

1

A8MUU1
CATPNSKILKEMCDM

KIF4B

1161

Q2VIQ3
DPTAVACTFSCMMKF

COPG1

716

Q9Y678
CMMKFTVKDCDPTTG

COPG1

726

Q9Y678
CPICLDMLKNTMTTK

RNF2

51

Q99496
NSCMDCNPAEKKIFM

GALNTL6

556

Q49A17
KAETSQAEKCMMPEC

SPON1

596

Q9HCB6
MMDPVAVCKKVGACH

PSAPL1

456

Q6NUJ1
VKCMLAEQKCPDHSM

SAMD3

156

Q8N6K7
LQNMKMANKCCSPSD

SNTG2

281

Q9NY99
MANKCCSPSDQVVHM

SNTG2

286

Q9NY99
CTKDNTPKIMEKCTM

OXCT2

441

Q9BYC2
LSKKGTCMFPSMCAR

STPG1

86

Q5TH74
AFKCMMCDVRKGTST

YAF2

36

Q8IY57
PMSMCSKRCQSGQKK

TAS1R2

491

Q8TE23
GPCKNCKMIMDTAGN

TIA1

31

P31483
KAKMDMCCAASPSQV

ZNF541

761

Q9H0D2
EAAMMTIATCAKCKS

ZNF518B

51

Q9C0D4
KETMCSSKNPIMSQC

MYO1C

571

O00159