Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	K63-linked polyubiquitin modification-dependent protein binding	WDR81 TAB2 NPLOC4 SQSTM1	2.98e-05	26	139	4	GO:0070530
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A LRRC37B	2.53e-09	4	134	4	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A LRRC37B	2.53e-09	4	134	4	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A LRRC37B	2.53e-09	4	134	4	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A LRRC37B	2.53e-09	4	134	4	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A LRRC37B	2.53e-09	4	134	4	IPR015753
Domain	DUF3827	KIAA1549 KIAA1549L	5.11e-05	2	134	2	PF12877
Domain	DUF3827	KIAA1549 KIAA1549L	5.11e-05	2	134	2	IPR024606
Domain	Elf-1_N	ELF2 ELF4	1.53e-04	3	134	2	PF12310
Domain	TF_Elf_N	ELF2 ELF4	1.53e-04	3	134	2	IPR022084
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.33e-17	12	148	8	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.12e-16	13	148	8	17668377
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.75e-16	8	148	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.60e-15	10	148	7	17984056
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	3.68e-14	13	148	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.11e-13	17	148	7	11245978
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	EVL NCOA6 GAPVD1 DNAJC13 PHRF1 DAB2 KDM3B ISL2 MCM4 HUWE1 GTF2IRD1 PNISR ZC3H11A BRPF1 CCNL1 ELF2 HSF1 PCM1 MRTFA PPP6R3 SON	1.77e-11	774	148	21	15302935
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PHRF1 KIAA1549 HUWE1 NCKAP5L MSL2 ZNF532 TRPM3 KNL1 PPP6R3	5.36e-10	101	148	9	10997877
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP32 DNAJC13 ZFYVE16 VEZT SIPA1L3 NAGLU KIAA1549 TNS2 TAB2 HUWE1 NCKAP5L CEP350 TOX4 NUP155 SSH3 MTMR3 PPP1R37 PHLPP1 MPHOSPH9 TRIM36 KNL1 PPP6R3	7.43e-10	1049	148	22	27880917
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOA6 RARG RHBDF2 PPRC1 SIPA1L3 NAGLU KDM3B AMBRA1 HUWE1 REV3L MED13L SRCAP GTF2IRD1 ATP13A2 ZC3H11A IGF1R SHANK2 CHST15 BTBD7 NCAPD2 MTMR3 NAV2	1.93e-09	1105	148	22	35748872
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOA6 ARHGAP32 DAB2 SYNGAP1 ZNF469 NUP155 ZNF532 SQSTM1 EIF4EBP1 NFKBIL1 BSN MRTFA TP73 SON	5.17e-09	430	148	14	35044719
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NCOA6 GAPVD1 PHRF1 KDM3B KIAA1549 AMBRA1 SRCIN1 NACAD NPLOC4 NUP155 ZNF532 NCAPD2 NAV2 BSN PPP6R3	9.13e-09	529	148	15	14621295
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	FOXO1 KLF8 DUX4L9 KDM3B ISL2 POU2F2 E2F2 DUX4L2 SRCAP TOX4 MTF1 BTBD7 BRPF1 ELF2 HSF1 DUX4L4 MRTFA NOBOX	1.18e-08	808	148	18	20412781
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	FOXO1 BAK1 E2F2 TAB2 HUWE1 SRCAP NCKAP5L ZZZ3 SQSTM1 BSN NXF1 PCM1 TP73 KNL1 PPP6R3	3.68e-08	588	148	15	38580884
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A LRRC37B	6.48e-08	10	148	4	23064749
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXO1 KLF8 RARG KIAA1549 ISL2 POU2F2 E2F2 SIX1 ZC3H11A TOX4 ZZZ3 MTF1 ELF2 ELF4 HSF1 ZNF541 TP73 NOBOX	6.90e-08	908	148	18	19274049
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SECISBP2L FOXO1 EVL GAPVD1 BMP2K DAB2 KDM3B WDR81 TAB2 NCKAP5L PNISR CEP350 SHANK2 SQSTM1 BTBD7 MPHOSPH9 HEATR5B MRTFA PPP6R3	1.00e-07	1038	148	19	26673895
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	GAPVD1 DNAJC13 ZFYVE16 HUWE1 TOX4 ZZZ3 ZNF532 SQSTM1 NXF1 PCM1 MRTFA KNL1	2.60e-07	418	148	12	34709266
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DAB2 MCM4 HUWE1 ZXDA ZC3H11A SQSTM1 SSH3 NCAPD2 NAV2 PCM1 MRTFA PPP6R3 SON	2.69e-07	503	148	13	16964243
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	3.01e-07	4	148	3	22419166
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L9 DUX4L2 DUX4L4	3.01e-07	4	148	3	17911620
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L9 DUX4L2 DUX4L4	3.01e-07	4	148	3	38509386
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZBTB2 VEZT PHRF1 KIAA1549 AMBRA1 E2F2 REV3L SRCAP NCKAP5L ZNF469 ZZZ3 SQSTM1 BRPF1 RTL9 NFKBIL1 PCM1 TP73 KNL1 SON	3.04e-07	1116	148	19	31753913
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	EVL ARHGAP32 SIPA1L3 TAB2 SRCIN1 NCKAP5L SYNGAP1 BSN PCM1	4.37e-07	218	148	9	33378226
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	NCOA6 DMXL2 SIPA1L3 KDM3B TAB2 MED13L NAV2 PHLPP1 MRTFA	5.69e-07	225	148	9	12168954
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA6 GAPVD1 MAP1B KDM3B HUWE1 SRCAP ZC3H11A TOX4 ZZZ3 ICAM5 NCAPD2 PCM1 PPP6R3	7.20e-07	549	148	13	38280479
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L9 DUX4L2 DUX4L4	7.50e-07	5	148	3	20063414
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FOXO1 NCOA6 ARHGAP32 GAPVD1 MAP1B SIPA1L3 BRSK2 KDM3B TAB2 NCKAP5L CEP350 IGF1R SQSTM1 NAV2 MPHOSPH9 PCM1	9.06e-07	861	148	16	36931259
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	MAP1B PHRF1 WDR81 PPP1R37 HYDIN KNL1	1.24e-06	80	148	6	19389623
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	COL5A1 EVL KLF8 DNAJC13 PDE9A RHBDF2 MAP1B VEZT SIPA1L3 TMEM63B SRCIN1 HUWE1 GTF2IRD1 SNX29 NPLOC4 ZC3H11A IGF1R SHANK2 ZNF532 CROCC PCM1	1.46e-06	1489	148	21	28611215
Pubmed	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	FOXO1 COL5A1 ZNF469	1.50e-06	6	148	3	20719862
Pubmed	The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.	DUX4L9 DUX4L2 DUX4L4	2.61e-06	7	148	3	30765463
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	GAPVD1 SIPA1L3 DAB2 SNX29 CEP350 SQSTM1 PCM1 PPP6R3	3.41e-06	209	148	8	36779422
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	DMXL2 ZFYVE16 BMP2K DAB2 SNX29 SQSTM1 PPP1R37 HEATR5B TRIM36	3.98e-06	285	148	9	34369648
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COL5A1 GAPVD1 MAP1B PHRF1 MCM4 HUWE1 ZC3H11A NUP155 NCAPD2 NXF1 PCM1 PPP6R3 SON	4.82e-06	653	148	13	22586326
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	LRRC37A3 PPRC1 SIPA1L3 LRRC37A CHST15 PHLPP1	6.10e-06	105	148	6	9628581
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MAPK8IP1 EVL ARHGAP32 DMXL2 MAP1B VEZT BRSK2 DAG1 SRCIN1 HUWE1 NACAD SYNGAP1 SHANK2 CAMKV SQSTM1 BSN PCM1	7.68e-06	1139	148	17	36417873
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NCOA6 MUC16 HUWE1 GTF2IRD1 NCKAP5L SQSTM1 HYDIN	8.83e-06	170	148	7	23314748
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SECISBP2L ARHGAP32 DMXL2 ZBTB2 SIPA1L3 BRSK2 MSL2 CEP350 TOX4 TTBK1 TRPM3	9.29e-06	493	148	11	15368895
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	DNAJC13 MAP1B ZFYVE16 BMP2K TAB2 SQSTM1 IRAK4 CROCC HEATR5B	1.06e-05	322	148	9	39098523
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GAPVD1 MAP1B ZFYVE16 KDM3B MCM4 SRCAP SNX29 NPLOC4 ZC3H11A TOX4 ELF2 PCM1 KNL1 PPP6R3 SON	1.16e-05	934	148	15	33916271
Pubmed	Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.	FOXO1 MAP1B SQSTM1 BSN	1.32e-05	34	148	4	25915474
Pubmed	Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites.	MAP1B SQSTM1 PCM1	1.62e-05	12	148	3	24089205
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	ZFYVE16 BMP2K SIPA1L3 DAB2 SQSTM1 PCM1	1.66e-05	125	148	6	29467281
Pubmed	Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.	RHBDF2 AREG	1.80e-05	2	148	2	28655741
Pubmed	Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction.	TRIM34 TRIM6	1.80e-05	2	148	2	24314652
Pubmed	Regulation of HSF1-responsive gene expression by N-terminal truncated form of p73alpha.	HSF1 TP73	1.80e-05	2	148	2	15081420
Pubmed	Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.	DUX4L9 DUX4	1.80e-05	2	148	2	24145033
Pubmed	AMBRA1 and SQSTM1 expression pattern in prostate cancer.	AMBRA1 SQSTM1	1.80e-05	2	148	2	26423274
Pubmed	Susceptibility to apoptosis in insulin-like growth factor-I receptor-deficient brown adipocytes.	FOXO1 IGF1R	1.80e-05	2	148	2	15356271
Pubmed	Genetic variants in the FOXO1 and ZNF469 genes are associated with keratoconus in Sweden: a case-control study.	FOXO1 ZNF469	1.80e-05	2	148	2	38267912
Pubmed	Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation.	TNS2 SQSTM1	1.80e-05	2	148	2	25101860
Pubmed	Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals.	TRIM34 TRIM6	1.80e-05	2	148	2	18159944
Pubmed	Impact of insulin-like growth factor-1 receptor and amphiregulin expression on survival in patients with stage II/III gastric cancer enrolled in the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer.	AREG IGF1R	1.80e-05	2	148	2	26884344
Pubmed	Nuclear translocation of IGF1R by intracellular amphiregulin contributes to the resistance of lung tumour cells to EGFR-TKI.	AREG IGF1R	1.80e-05	2	148	2	29421153
Pubmed	Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.	FOXO1 ZNF469	1.80e-05	2	148	2	20485516
Pubmed	Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.	RHBDF2 AREG	1.80e-05	2	148	2	25395669
Pubmed	UBE2T promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation.	FOXO1 UBE2T	1.80e-05	2	148	2	32590022
Pubmed	E2F2 is upregulated by the ERK pathway and regulates decidualization via MCM4.	MCM4 E2F2	1.80e-05	2	148	2	37028609
Pubmed	Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.	RHBDF2 AREG	1.80e-05	2	148	2	29116018
Pubmed	A protein interaction landscape of breast cancer.	EVL GAPVD1 BMP2K SIPA1L3 DAB2 DAG1 AREG TOX4 SQSTM1 NAV2 PCM1 PPP6R3	1.86e-05	634	148	12	34591612
Pubmed	A germline-specific class of small RNAs binds mammalian Piwi proteins.	BMP2K LRRC37A2 BRSK2 NPLOC4 MTF1 SQSTM1 NCAPD2 MTMR3 BSN SON	2.48e-05	450	148	10	16751776
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L9 DUX4L2 DUX4L4	3.31e-05	15	148	3	35727972
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	DUX4L9 DUX4L2 DUX4L4	3.31e-05	15	148	3	30071041
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	CEP350 ZC3H11A SQSTM1 NCAPD2 PCM1 KNL1 SON	3.45e-05	210	148	7	16565220
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAPK8IP1 EVL ARHGAP32 DMXL2 DNAJC13 MAP1B SIPA1L3 BRSK2 KIAA1549 SRCIN1 SYNGAP1 SHANK2 CAMKV ICAM5 NCAN BSN CROCC PCM1	4.00e-05	1431	148	18	37142655
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	GAPVD1 BMP2K LRRC37A3 DAB2 RAET1E TRIM6 ATP13A2 ICAM5 SSH3 MPHOSPH9 SUCO PCM1 MRTFA TP73	4.39e-05	925	148	14	28986522
Pubmed	A human MAP kinase interactome.	ARHGAP32 DAB2 NCKAP5L PNISR MSL2 CEP350 TOX4 KIAA1549L NAV2 MPHOSPH9	4.73e-05	486	148	10	20936779
Pubmed	JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.	MAP1B DAG1 SHANK2	4.91e-05	17	148	3	26627310
Pubmed	The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells.	IGF1R TP73	5.38e-05	3	148	2	16181796
Pubmed	Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor.	DCC TP73	5.38e-05	3	148	2	18922894
Pubmed	Molecular cloning of ring finger protein 21 (RNF21)/interferon-responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem.	TRIM34 TRIM6	5.38e-05	3	148	2	11013086
Pubmed	p73 and IGF1R Regulate Emergence of Aggressive Cancer Stem-like Features via miR-885-5p Control.	IGF1R TP73	5.38e-05	3	148	2	26554827
Pubmed	circCHST15 is a novel prognostic biomarker that promotes clear cell renal cell carcinoma cell proliferation and metastasis through the miR-125a-5p/EIF4EBP1 axis.	CHST15 EIF4EBP1	5.38e-05	3	148	2	34922539
Pubmed	Associations between multiple system atrophy and polymorphisms of SLC1A4, SQSTM1, and EIF4EBP1 genes.	SQSTM1 EIF4EBP1	5.38e-05	3	148	2	18442140
Pubmed	DNp73 exerts function in metastasis initiation by disconnecting the inhibitory role of EPLIN on IGF1R-AKT/STAT3 signaling.	IGF1R TP73	5.38e-05	3	148	2	24135282
Pubmed	Coactivator ASC-2 mediates heat shock factor 1-mediated transactivation dependent on heat shock.	NCOA6 HSF1	5.38e-05	3	148	2	14960326
Pubmed	Differential regulation of the proapoptotic multidomain protein Bak by p53 and p73 at the promoter level.	BAK1 TP73	5.38e-05	3	148	2	21233848
Pubmed	Survival is associated with genetic variation in inflammatory pathway genes among patients with resected and unresected pancreatic cancer.	MAPK8IP1 IGF1R	5.38e-05	3	148	2	23360921
Pubmed	HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.	AMBRA1 HUWE1	5.38e-05	3	148	2	31434979
Pubmed	IGF-1 Receptor Modulates FoxO1-Mediated Tamoxifen Response in Breast Cancer Cells.	FOXO1 IGF1R	5.38e-05	3	148	2	28096479
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	GAPVD1 MAP1B ZFYVE16 GTF2IRD1 PNISR SQSTM1 PPP1R37	5.48e-05	226	148	7	31452512
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXO1 RARG POU2F2 E2F2 SIX1 GTF2IRD1 TOX4 ZZZ3 ZNF532 MTF1 SQSTM1 BRPF1	5.50e-05	709	148	12	22988430
Pubmed	Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.	HUWE1 NPLOC4 UBE2T SQSTM1	6.23e-05	50	148	4	17550899
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	MAP1B AMBRA1 MCM4 HUWE1 GTF2IRD1 KNL1 SON	6.47e-05	232	148	7	25515538
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZFYVE16 PPRC1 MED13L ZC3H11A CHST15 BTBD7 MTMR3 CROCC SON	6.60e-05	407	148	9	12693553
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAPK8IP1 ARHGAP32 DMXL2 DNAJC13 SIPA1L3 WDR81 HUWE1 SYNGAP1 SHANK2 CAMKV ICAM5 NCAN BSN PCM1	6.74e-05	963	148	14	28671696
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	GAPVD1 ZFYVE16 VEZT KDM3B HUWE1 NCKAP5L CEP350 SQSTM1 MPHOSPH9 CROCC PCM1 KNL1	7.54e-05	733	148	12	34672954
Pubmed	TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.	AMBRA1 TRIM6 SQSTM1	8.16e-05	20	148	3	25127057
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	GAPVD1 ZBTB2 PHRF1 NPLOC4 BTBD7	8.16e-05	103	148	5	10819331
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZFYVE16 HUWE1 SRCAP NACAD MTMR3	8.55e-05	104	148	5	9205841
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KDM3B TNS2 MED13L SHANK2 SON	8.55e-05	104	148	5	10470851
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	MAP1B SRCIN1 HUWE1 CAMKV SQSTM1 PCM1 PPP6R3	9.32e-05	246	148	7	15345747
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOA6 ARHGAP32 LRRC37A3 KDM3B MUC16 TAB2 REV3L CEP350 ASXL3 BSN KNL1	9.62e-05	638	148	11	31182584
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	ARHGAP32 TAB2 NCKAP5L SNX29 CEP350 MPHOSPH9 PCM1	1.06e-04	251	148	7	29778605
Pubmed	RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?	RHBDF2 AREG	1.07e-04	4	148	2	30022999
Pubmed	Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas.	FOXO1 INPP4B	1.07e-04	4	148	2	23078915
Pubmed	An expanded clade of rodent Trim5 genes.	TRIM34 TRIM6	1.07e-04	4	148	2	19147168
Pubmed	SCOP/PHLPP1β mediates circadian regulation of long-term recognition memory.	ICAM5 PHLPP1	1.07e-04	4	148	2	27686624
Pubmed	Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness.	COL5A1 ZNF469	1.07e-04	4	148	2	22814818
Interaction	PHF21A interactions	KLF8 GAPVD1 DNAJC13 ZFYVE16 HUWE1 NCKAP5L TOX4 ZZZ3 SQSTM1 PCM1 MRTFA KNL1	5.45e-06	343	141	12	int:PHF21A
Interaction	PLK1 interactions	GAPVD1 MAP1B GRB7 TNS2 MCM4 NUP155 SQSTM1 MTMR3 PHLPP1 TRIM36 HSF1 PCM1 TP73 PPP6R3	1.42e-05	510	141	14	int:PLK1
Interaction	YWHAG interactions	FOXO1 NCOA6 ARHGAP32 GAPVD1 SIPA1L3 KDM3B TNS2 TAB2 HUWE1 NCKAP5L MSL2 SYNGAP1 CEP350 TTBK1 IGF1R SQSTM1 MTMR3 NAV2 MPHOSPH9 SUCO PCM1 PPP6R3 SON	1.83e-05	1248	141	23	int:YWHAG
Interaction	CEP135 interactions	ARHGAP32 SIPA1L3 NCKAP5L CEP350 NUP155 SQSTM1 RTL9 MPHOSPH9 TRIM36 PCM1	2.22e-05	272	141	10	int:CEP135
Interaction	NUDC interactions	FOXO1 MAP1B AMBRA1 DUX4 HUWE1 SYNGAP1 ZNF532 PHLPP1 HSF1 HYDIN NXF1	2.58e-05	337	141	11	int:NUDC
Interaction	POLH interactions	MCM4 REV3L NPLOC4 PHLPP1 NXF1 KNL1	2.74e-05	84	141	6	int:POLH
Interaction	YWHAZ interactions	FOXO1 EVL ARHGAP32 DMXL2 GAPVD1 SIPA1L3 TAB2 HUWE1 NCKAP5L MSL2 SYNGAP1 IGF1R CAMKV SQSTM1 ASXL3 SSH3 MTMR3 NAV2 MPHOSPH9 HSF1 SUCO NXF1 PCM1	4.34e-05	1319	141	23	int:YWHAZ
Interaction	RCOR1 interactions	DNAJC13 ZFYVE16 HUWE1 NCKAP5L TOX4 ZZZ3 SQSTM1 NCAPD2 NXF1 PCM1 MRTFA KNL1 PPP6R3	4.49e-05	494	141	13	int:RCOR1
Interaction	PSMC3 interactions	KLF8 GAPVD1 MAP1B ZFYVE16 AMBRA1 HUWE1 ZZZ3 SQSTM1 NCAPD2 ELF2 HSF1 NXF1	4.55e-05	425	141	12	int:PSMC3
Interaction	SQSTM1 interactions	FOXO1 ARHGAP32 GAPVD1 DNAJC13 MAP1B ZFYVE16 BMP2K SIPA1L3 WDR81 AMBRA1 TAB2 HUWE1 CEP350 NUP155 CAMKV SQSTM1 IRAK4 PHLPP1 CROCC HEATR5B NXF1 PPP6R3	6.16e-05	1257	141	22	int:SQSTM1
Interaction	KPNA2 interactions	FOXO1 GAPVD1 ZBTB2 MAP1B MCM4 HUWE1 GTF2IRD1 NUP155 SQSTM1 ASXL3 NCAPD2 HSF1 NXF1	7.42e-05	519	141	13	int:KPNA2
Interaction	RGPD6 interactions	HUWE1 NUP155 NXF1 PCM1	8.02e-05	33	141	4	int:RGPD6
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.84e-10	27	148	6	4q35.2
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.89e-09	117	148	8	chr4q35
Cytoband	6q25.1	ZBTB2 TAB2 RAET1E	2.55e-04	38	148	3	6q25.1
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L9 DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 NOBOX	2.16e-08	92	92	8	521
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MAP1B ZFYVE16 PHRF1 WDR81 PPP1R37 HYDIN KNL1	3.84e-05	181	92	7	694
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ZFYVE16 MTMR3 FGD3	5.17e-04	31	92	3	81
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SECISBP2L DMXL2 GAPVD1 DNAJC13 MAP1B ZFYVE16 BMP2K KDM3B TAB2 REV3L MED13L PNISR CEP350 IGF1R ZZZ3 MTMR3 PHLPP1 MPHOSPH9 SUCO MRTFA SON	1.27e-08	856	146	21	M4500
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	FOXO1 GAPVD1 PPRC1 REV3L MED13L PNISR CEP350 ZZZ3 PHLPP1 ELF2 SUCO	1.02e-06	300	146	11	M8702
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 LRRC37A3 SIPA1L3 AMBRA1 MED13L IGF1R SHANK2 NAV2	2.34e-07	198	141	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 LRRC37A3 SIPA1L3 AMBRA1 MED13L IGF1R SHANK2 PPP6R3	2.44e-07	199	141	8	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5\|TCGA-Pancreas / Sample_Type by Project: Shred V9	RHBDF2 MUC16 MCM4 GTF2IRD1 INPP4B ICAM5 HSF1	1.40e-06	174	141	7	73e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	LRRC37A3 SIPA1L3 AMBRA1 MED13L IGF1R SHANK2 NAV2	3.09e-06	196	141	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	SECISBP2L ARHGAP32 TMEM63B GRB7 PNISR CCNL1 NAV2	3.19e-06	197	141	7	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	TMEM63B GRB7 SHANK2 TRPM3 ICAM5 NAV2 FGD3	3.30e-06	198	141	7	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TMEM63B GRB7 SHANK2 TRPM3 ICAM5 NAV2 FGD3	3.41e-06	199	141	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	COVID_vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	FOXO1 EVL TAB2 PNISR INPP4B IGF1R CCNL1	3.41e-06	199	141	7	885bc902b6e2af0b61e452c4154160cd3f1cf98e
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TMEM63B GRB7 SHANK2 TRPM3 ICAM5 NAV2 FGD3	3.53e-06	200	141	7	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BRSK2 KIAA1549 SRCIN1 TTBK1 CAMKV TP73	1.30e-05	162	141	6	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MCM4 E2F2 GTF2IRD1 UBE2T NCAPD2 KNL1	1.40e-05	164	141	6	fb18b863152fb3109e2224c791c84c6371680a4e
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZBTB2 INPP4B UBE2T NCAPD2 CROCC KNL1	1.55e-05	167	141	6	754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T\|Lung / Manually curated celltypes from each tissue	MCM4 E2F2 UBE2T NCAPD2 TP73 KNL1	2.08e-05	176	141	6	a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell	Mild/Remission-B_naive-12\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DAB2 SRCIN1 SSC5D ZZZ3 TRPM3	2.32e-05	107	141	5	1ab09acb66e4282688fd1f6782a4009f4ea18c41
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP1B KIAA1549 PERM1 NCAN HYDIN TP73	2.59e-05	183	141	6	6f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SECISBP2L RARG PDE9A TMEM63B GRB7 KIAA1549L	2.93e-05	187	141	6	6e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL5A1 MAP1B REV3L INPP4B CHST15 NAV2	2.93e-05	187	141	6	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SECISBP2L RARG PDE9A TMEM63B GRB7 KIAA1549L	2.93e-05	187	141	6	43ef900b76f3c38bd8ce9858201124130c743d56
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SECISBP2L SIPA1L3 GRB7 SHANK2 TRPM3 NAV2	2.93e-05	187	141	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MCM4 E2F2 GTF2IRD1 UBE2T NCAPD2 KNL1	3.02e-05	188	141	6	f5102e8d95506c25c675094b86162a6a50087b64
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 MED13L SNX29 IGF1R SHANK2 TRPM3	3.39e-05	192	141	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXO1 AMBRA1 MED13L SNX29 MRTFA PPP6R3	3.49e-05	193	141	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZFYVE16 DAG1 HUWE1 ZXDA CEP350 SON	3.49e-05	193	141	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MCM4 E2F2 UBE2T NCAPD2 PROB1 KNL1	3.49e-05	193	141	6	cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SIPA1L3 GTF2IRD1 SNX29 IGF1R SHANK2 TRPM3	3.49e-05	193	141	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GTF2IRD1 SNX29 SHANK2 TRPM3 TMEM72 HYDIN	3.60e-05	194	141	6	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RHBDF2 BAK1 E2F2 TNFRSF10C DCC CHST15	3.70e-05	195	141	6	c6e31038be2463f1601d52c82efa4e9facb8228f
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	RARG NCKAP5L NACAD ZNF469 NAV2 ELF4	3.70e-05	195	141	6	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FOXO1 COL5A1 ARHGAP32 REV3L ELF2 MRTFA	3.70e-05	195	141	6	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B HUWE1 REV3L NAV2 PCM1 SON	3.70e-05	195	141	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL5A1 MAP1B REV3L INPP4B CHST15 NAV2	3.70e-05	195	141	6	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B HUWE1 REV3L NAV2 PCM1 SON	3.70e-05	195	141	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE9A TMEM116 SIPA1L3 GTF2IRD1 SNX29 SHANK2	3.81e-05	196	141	6	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SECISBP2L TMEM63B GRB7 SHANK2 ICAM5 SON	3.92e-05	197	141	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	FOXO1 EVL PDE9A PNISR INPP4B IGF1R	3.92e-05	197	141	6	836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell	(3)_DC_Monocyte_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	MCM4 E2F2 TASL UBE2T NCAPD2 KNL1	4.03e-05	198	141	6	e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP1B UBE2T ADGRG2 NCAPD2 NAV2 KNL1	4.14e-05	199	141	6	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	COL5A1 MAP1B REV3L INPP4B CHST15 NAV2	4.14e-05	199	141	6	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	TMEM63B GRB7 SHANK2 TRPM3 NAV2 SON	4.26e-05	200	141	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TMEM63B GRB7 SHANK2 TRPM3 ICAM5 NAV2	4.26e-05	200	141	6	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MED13L PNISR CEP350 CCNL1 PCM1 SON	4.26e-05	200	141	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	EVL MAP1B POU2F2 CAMKV ASXL3 TRIM36	4.26e-05	200	141	6	68c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Meis2-Meis2_Adamts19\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ISL2 SSC5D HYDIN SON	6.82e-05	69	141	4	130b1a56afe6aee01cde56cb983cbc2c41861bb4
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Meis2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ISL2 SSC5D HYDIN SON	6.82e-05	69	141	4	6568fcefcc0dca211f2acf6e4066f795489e758d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZAN ISL2 POU2F2 DUX4 TASL	9.24e-05	143	141	5	360a2ea8b64e3b9084f4c4cb8beb0d44106b9edb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZAN ISL2 POU2F2 DUX4 TASL	9.24e-05	143	141	5	605532fc0f32979b306cbb58f8796df7d6b24828
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZAN ISL2 POU2F2 DUX4 TASL	9.24e-05	143	141	5	5cc59deb5a8af8095c1581e585eaeeecdd938621
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 TMEM63B INPP4B CCNL1 NAV2	1.35e-04	155	141	5	82e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 TMEM63B INPP4B CCNL1 NAV2	1.35e-04	155	141	5	979c1d53b435a82c57d16707eed8ba7346326866
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MCM4 E2F2 UBE2T TP73 KNL1	1.91e-04	167	141	5	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UBE2T NCAPD2 PPP1R37 MPHOSPH9 MRTFA	1.96e-04	168	141	5	9b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF8 TMEM116 CHST15 CAMKV ICAM5	1.96e-04	168	141	5	b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF8 TMEM116 CHST15 CAMKV ICAM5	1.96e-04	168	141	5	b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UBE2T NCAPD2 PPP1R37 MPHOSPH9 MRTFA	1.96e-04	168	141	5	4b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UBE2T NCAPD2 PPP1R37 MPHOSPH9 MRTFA	1.96e-04	168	141	5	c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SECISBP2L FOXO1 ARHGAP32 SNX29 HEATR5B	2.02e-04	169	141	5	c3a6179a64589a370108fea809b157839347759c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 SYNGAP1 SHANK2 HYDIN TP73	2.13e-04	171	141	5	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	MCM4 E2F2 UBE2T NCAPD2 KNL1	2.19e-04	172	141	5	8d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCell	E17.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SECISBP2L TMEM116 SNX29 INPP4B AREG	2.31e-04	174	141	5	68914ec843f58ecff3e6412544a341daf8a01cac
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXO1 ZAN PDE9A GRB7 RAET1E	2.31e-04	174	141	5	268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	MCM4 E2F2 TRIM34 UBE2T KNL1	2.31e-04	174	141	5	a75ba49ccea6bd3d78ada1092b46deb5202c58a5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	E2F2 KRBA2 UBE2T NCAPD2 KNL1	2.31e-04	174	141	5	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXO1 ZAN PDE9A GRB7 RAET1E	2.31e-04	174	141	5	4cdf2eedc28d88d18241ee390092426fdf849e79
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	MCM4 E2F2 NCAPD2 TP73 KNL1	2.31e-04	174	141	5	e4c8da80eca07e4396f57dad212f76c2eca4c1bd
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	LRRC37A3 DAB2 MED13L ATP13A2 LRRC37A	2.37e-04	175	141	5	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	wk_20-22-Hematologic-Myeloid-Promyelocyte-like\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KDM3B MCM4 LRRC37A NCAPD2 NXF1	2.43e-04	176	141	5	ee33d7077a92c1fd371081e7c990c7266e711957
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MCM4 E2F2 UBE2T EIF4EBP1 KNL1	2.50e-04	177	141	5	f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POU2F2 E2F2 DCC CHST15 TP73	2.57e-04	178	141	5	f815bc76f98aaea2d9058173b02b6f36e45283ce
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	POU2F2 E2F2 DCC CHST15 TP73	2.57e-04	178	141	5	a0334764e865fea652c54b94bbc3b173f7cbc9fc
ToppCell	(5)_Epithelial_cells-(5)_Glands_mucous\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	DAB2 MUC16 TNFRSF10C SIX1 ADGRG2	2.70e-04	180	141	5	a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE9A MAP1B KIAA1549 KIAA1549L SSH3	2.77e-04	181	141	5	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE9A MAP1B KIAA1549 KIAA1549L SSH3	2.77e-04	181	141	5	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 TRIM6 CHST15 BTBD7 CD300LG	2.77e-04	181	141	5	a53f05c4c47465ee62e353716456bd09ab464b23
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE9A MAP1B KIAA1549 KIAA1549L SSH3	2.77e-04	181	141	5	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN DCC TRPM3 ASXL3 HYDIN	2.99e-04	184	141	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_int\|lung / Disease (COVID-19 only), tissue and cell type	POU2F2 E2F2 DCC CHST15 KNL1	2.99e-04	184	141	5	480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	COL5A1 MAP1B SSC5D ZNF469 RTL9	2.99e-04	184	141	5	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN DCC TRPM3 ASXL3 HYDIN	2.99e-04	184	141	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN DCC TRPM3 ASXL3 HYDIN	2.99e-04	184	141	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SECISBP2L ARHGAP32 SHANK2 TRPM3 NAV2	3.06e-04	185	141	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARG INPP4B AREG IGF1R WFIKKN2	3.06e-04	185	141	5	ea3ff0bd3f312bd2e93227ecf6ed577366aab3e0
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	DMXL2 GAPVD1 MCM4 HUWE1 NUP155	3.06e-04	185	141	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	DMXL2 RHBDF2 BMP2K DAB2 CHST15	3.06e-04	185	141	5	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	WDR81 AMBRA1 SSC5D ZZZ3 NCAPD2	3.06e-04	185	141	5	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	WDR81 AMBRA1 SSC5D ZZZ3 NCAPD2	3.06e-04	185	141	5	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	3'_v3-blood-Lymphocytic_T_CD4/8-lo\|blood / Manually curated celltypes from each tissue	MCM4 E2F2 UBE2T NCAPD2 KNL1	3.06e-04	185	141	5	df85ff34b796b403f2d0741771e9592e03657f6a
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFYVE16 NUP155 ASXL3 IRAK4 NXF1	3.14e-04	186	141	5	39e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|lung / Disease (COVID-19 only), tissue and cell type	POU2F2 E2F2 DCC CHST15 KNL1	3.14e-04	186	141	5	66676d9395172de5707e204826a1c9f73b448cca
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 PERM1 PCDHB18P IGF1R CD300LG	3.14e-04	186	141	5	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DMXL2 GAPVD1 MCM4 HUWE1 NUP155	3.14e-04	186	141	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 PERM1 PCDHB18P IGF1R CD300LG	3.14e-04	186	141	5	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFYVE16 NUP155 ASXL3 IRAK4 NXF1	3.14e-04	186	141	5	02418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU2F2 KIAA1549L CAMKV ICAM5 BSN	3.14e-04	186	141	5	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AREG SQSTM1 CCNL1 PCM1 SON	3.22e-04	187	141	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 E2F2 NCAPD2 TP73 KNL1	3.22e-04	187	141	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ZFYVE16 DAB2 REV3L PNISR ELF2	3.22e-04	187	141	5	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 E2F2 NCAPD2 TP73 KNL1	3.22e-04	187	141	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	10x5'-Liver-Lymphocytic_NK-Cycling_NK\|Liver / Manually curated celltypes from each tissue	MCM4 E2F2 UBE2T NCAPD2 KNL1	3.30e-04	188	141	5	5eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	COL5A1 NCOA6 LRRC37A3 NCKAP5L ZNF469	3.30e-04	188	141	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE9A SHANK2 TRPM3 TMEM72 NPAP1	3.30e-04	188	141	5	8f9996c3f3b27efaaae8960a66af77412de9c7ef
Drug	Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; PC3; HT_HG-U133A	ARHGAP32 BMP2K AMBRA1 TNS2 SIX1 SRCAP PNISR IGF1R IRAK4	4.78e-06	192	148	9	7155_DN
Drug	Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; MCF7; HT_HG-U133A	SECISBP2L COL5A1 RARG SIPA1L3 GRB7 PNISR SQSTM1 SSH3 MRTFA	6.39e-06	199	148	9	1703_DN
Drug	Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A	COL5A1 RARG GRB7 TNFRSF10C SRCAP SNX29 ADGRG2 MTMR3 MRTFA	6.66e-06	200	148	9	2769_UP
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	NCOA6 PPRC1 REV3L MED13L PNISR IGF1R ZZZ3 ELF4	1.59e-05	170	148	8	1050_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	NCOA6 PPRC1 MED13L GTF2IRD1 IGF1R ZZZ3 ELF4 SON	1.73e-05	172	148	8	1072_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	RARG PPRC1 GTF2IRD1 PNISR MSL2 IGF1R CHST15 ELF4	2.04e-05	176	148	8	981_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	RARG REV3L MED13L MSL2 CEP350 ZZZ3 CHST15 SON	2.60e-05	182	148	8	3887_DN
Drug	2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A	DMXL2 MAP1B TNFRSF10C SIX1 SRCAP IGF1R TRPM3 NCAN	3.95e-05	193	148	8	5600_UP
Drug	Resveratrol [501-36-0]; Up 200; 17.6uM; HL60; HG-U133A	ARHGAP32 ZFYVE16 GRB7 AMBRA1 POU2F2 TRPM3 SQSTM1 NXF1	3.95e-05	193	148	8	1715_UP
Drug	Leucomisine [17946-87-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A	FOXO1 RARG VEZT NAGLU GRB7 SRCAP SHANK2 ELF4	4.10e-05	194	148	8	6767_DN
Drug	semduramicin	NCOA6 SHANK2	4.20e-05	2	148	2	CID000071327
Drug	Ketoconazole [65277-42-1]; Down 200; 7.6uM; PC3; HT_HG-U133A	FOXO1 RARG DAG1 SIX1 ADGRG2 CROCC PCM1 MRTFA	4.40e-05	196	148	8	4624_DN
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; PC3; HT_HG-U133A	FOXO1 RARG SIPA1L3 NAGLU AMBRA1 IRAK4 PCM1 MRTFA	4.57e-05	197	148	8	7401_UP
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HG-U133A	EVL DNAJC13 RHBDF2 SIPA1L3 DAB2 SSH3 MPHOSPH9 SON	4.73e-05	198	148	8	1913_DN
Drug	Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A	SECISBP2L RARG SIPA1L3 SRCAP CEP350 SSH3 PHLPP1 PCM1	4.73e-05	198	148	8	3292_DN
Drug	Tranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; MCF7; HT_HG-U133A	SECISBP2L RARG ZFYVE16 SIPA1L3 NAGLU AMBRA1 MTMR3 MRTFA	5.08e-05	200	148	8	5996_DN
Disease	Intellectual Disability	KLF8 MAP1B NAGLU BRSK2 KDM3B MED13L DCC SYNGAP1 SHANK2 TRPM3 MTF1	8.75e-06	447	138	11	C3714756
Disease	nephroblastoma (is_implicated_in)	SIX1 IGF1R TP73	3.51e-05	14	138	3	DOID:2154 (is_implicated_in)
Disease	Neurodevelopmental Disorders	BRSK2 MED13L SRCAP SYNGAP1 ASXL3	7.77e-05	93	138	5	C1535926
Disease	Parkinson's disease (implicated_via_orthology)	FOXO1 BMP2K PPRC1 ATP13A2 IGF1R HSF1	9.94e-05	157	138	6	DOID:14330 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	EVL NCOA6 RARG LRRC37A2 GRB7 INPP4B AREG ZC3H11A IGF1R LRRC37A ZNF532 ICAM5 MTMR3 ZNF541 TP73	1.58e-04	1074	138	15	C0006142
Disease	Alzheimer disease, educational attainment	DAG1 DCC SNX29 CAMKV PPP1R37 BSN TRIM36	1.69e-04	247	138	7	EFO_0011015, MONDO_0004975
Disease	Alveolar rhabdomyosarcoma	FOXO1 TP73	2.15e-04	5	138	2	C0206655
Disease	Breast Carcinoma	EVL LRRC37A2 GRB7 INPP4B AREG ZC3H11A IGF1R LRRC37A ICAM5 TP73	2.30e-04	538	138	10	C0678222
Disease	eye measurement	FOXO1 COL5A1 ZNF469	2.70e-04	27	138	3	EFO_0004731
Disease	glucose measurement	MAPK8IP1 ZAN LRRC37A3 SYNGAP1 IGF1R LRRC37A MTMR3 BSN	4.36e-04	380	138	8	EFO_0004468
Disease	Profound Mental Retardation	NAGLU MED13L DCC SYNGAP1 SHANK2	5.06e-04	139	138	5	C0020796
Disease	Mental Retardation, Psychosocial	NAGLU MED13L DCC SYNGAP1 SHANK2	5.06e-04	139	138	5	C0025363
Disease	Mental deficiency	NAGLU MED13L DCC SYNGAP1 SHANK2	5.06e-04	139	138	5	C0917816
Disease	Congenital Hydrocephalus	WDR81 HYDIN	5.97e-04	8	138	2	C0020256
Disease	Mammary Carcinoma, Human	EVL LRRC37A2 GRB7 AREG ZC3H11A IGF1R LRRC37A ICAM5 TP73	8.43e-04	525	138	9	C4704874
Disease	Mammary Neoplasms, Human	EVL LRRC37A2 GRB7 AREG ZC3H11A IGF1R LRRC37A ICAM5 TP73	8.43e-04	525	138	9	C1257931
Disease	Mammary Neoplasms	EVL LRRC37A2 GRB7 AREG ZC3H11A IGF1R LRRC37A ICAM5 TP73	8.66e-04	527	138	9	C1458155
Disease	prostatic hypertrophy (is_marker_for)	IGF1R TP73	1.16e-03	11	138	2	DOID:11132 (is_marker_for)
Disease	cryptorchidism (biomarker_via_orthology)	IGF1R HSF1	1.16e-03	11	138	2	DOID:11383 (biomarker_via_orthology)
Disease	quality of life during menstruation measurement, decreased attention	IGF1R TRIM36	1.39e-03	12	138	2	EFO_0009366, NCIT_C117245
Disease	obsolete_red blood cell distribution width	DNAJC13 BMP2K LRRC37A2 TMEM63B E2F2 SLFN14 NPLOC4 INPP4B ZC3H11A IGF1R SQSTM1 CD300LG LRRC37B KNL1 PPP6R3	1.63e-03	1347	138	15	EFO_0005192
Disease	C-C motif chemokine 19 measurement	DNAJC13 BSN	1.90e-03	14	138	2	EFO_0008047
Disease	macula measurement	ARHGAP32 SYNGAP1 TMEM72 MTMR3 NAV2	1.99e-03	189	138	5	EFO_0008375
Disease	parental longevity	GAPVD1 PERM1 DCC SNX29 CEP350 CCNL1 PHLPP1 BSN	2.33e-03	494	138	8	EFO_0007796
Disease	Abnormal behavior	BRSK2 KDM3B	2.50e-03	16	138	2	C0233514
Disease	primary autosomal recessive microcephaly (is_implicated_in)	NCAPD2 KNL1	2.50e-03	16	138	2	DOID:0070296 (is_implicated_in)
Disease	creatinine measurement	KLF8 GAPVD1 DNAJC13 SIPA1L3 DAB2 NPLOC4 AREG IGF1R ZZZ3 MTMR3 BSN MRTFA	2.53e-03	995	138	12	EFO_0004518
Disease	platelet component distribution width	GAPVD1 BMP2K SLFN14 INPP4B TOX4 IGF1R TRPM3 MTF1 BTBD7 FGD3	2.98e-03	755	138	10	EFO_0007984
Disease	SARS-CoV-2 antibody measurement, response to COVID-19 vaccine	COL5A1 TAB2 MED13L	3.09e-03	62	138	3	EFO_0803360, EFO_0803362
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	TNFRSF10C AREG IGF1R ELF2	3.39e-03	131	138	4	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	TNFRSF10C AREG IGF1R ELF2	3.39e-03	131	138	4	C4552091
Disease	Juvenile arthritis	TNFRSF10C AREG IGF1R ELF2	3.39e-03	131	138	4	C3495559
Disease	Juvenile psoriatic arthritis	TNFRSF10C AREG IGF1R ELF2	3.39e-03	131	138	4	C3714758
Disease	Global developmental delay	BRSK2 KDM3B IGF1R TRPM3	3.58e-03	133	138	4	C0557874
Disease	keratoconus	FOXO1 COL5A1 ZNF469	3.69e-03	66	138	3	MONDO_0015486
Disease	Juvenile-Onset Still Disease	TNFRSF10C AREG IGF1R ELF2	3.78e-03	135	138	4	C0087031
Disease	corneal hysteresis	FOXO1 ZNF469	3.90e-03	20	138	2	EFO_0010066
Disease	lifestyle measurement, anxiety disorder measurement	SNX29 NPLOC4 SHANK2 TRPM3	3.98e-03	137	138	4	EFO_0007795, EFO_0010724
Disease	bipolar I disorder	MAPK8IP1 KDM3B SHANK2 NCAN	4.41e-03	141	138	4	EFO_0009963
Disease	systemic lupus erythematosus	TMEM116 PHRF1 DAB2 SRCAP GTF2IRD1 TASL SYNGAP1 TOX4 MTF1 ICAM5	4.43e-03	799	138	10	MONDO_0007915

Protein segments in the cluster

Peptide	Gene	Start	Entry
AEDSNMSVPSEPSSP	PRPF4B	556	Q13523
SEISPVSEMPSSSEP	AREG	61	P15514
ADPEMVTLPLQPSST	BAK1	56	Q16611
MALPTPSDSTLPAEA	DUX4L4	1	P0CJ87
PPVTTHNMIDDSTDP	GYS2	441	P54840
VTSPSSDEPPMEASQ	EIF4EBP1	81	Q13541
ASSPAIDMPPQSETI	ADGRG2	311	Q8IZP9
NVDSSPETSPSVSPM	DMXL2	941	Q8TDJ6
MALPTPSDSTLPAEA	DUX4L6	1	P0CJ89
EAESMPPPRTSASSV	AMBRA1	431	Q9C0C7
PTPSMQDGLDLPSET	CCNL1	66	Q9UK58
SSIPSALPEPMTASE	BMP2K	331	Q9NSY1
PVSNLPLTSETSPMS	ASXL3	706	Q9C0F0
PLTSETSPMSDLPLT	ASXL3	711	Q9C0F0
NTPEPIIMSSSSIAP	ASXL3	806	Q9C0F0
ADTFNEMQPPSSEPS	NAGLU	311	P54802
EAMPEPTVSPVNASD	RAET1E	201	Q8TD07
QSTSSEEMVPSSPSP	RARG	66	P13631
TFPEPPMLLTSDQTL	NOBOX	411	O60393
PEIAMTSLTSPIPEN	PCDHB18P	291	Q96TA0
TSLTSPIPENSSPEM	PCDHB18P	296	Q96TA0
PSEAPASLSLMPSDL	KIAA1549	641	Q9HCM3
FGDMSTPPDLNSPTE	DAB2	216	P98082
DSTSTGELQPMPTSP	MCM4	41	P33991
DMLDTSLEPVTTSPP	MUC16	8896	Q8WXI7
LTLSPGEPETTPSMA	MUC16	10896	Q8WXI7
LTLSPGEPETTPSMA	MUC16	11006	Q8WXI7
DDFPTSVPDLSTPML	DCC	831	P43146
ASSEMPAPPQESTEN	LRRC37A3	91	O60309
APALPPESSMESLTL	LRRC37A3	261	O60309
PSDMQDSSLSHKIPP	MAP1B	1691	P46821
MSTPTLEEEPASNPA	MED13L	396	Q71F56
PSTTRPLNSVEPATM	MED13L	1086	Q71F56
MALPTPSDSTLPAEA	DUX4	1	Q9UBX2
ASSEMPAPPQESTEN	LRRC37A2	91	A6NM11
APALPPESSMESLTL	LRRC37A2	261	A6NM11
ASSEMPAPPQESTEN	LRRC37A	91	A6NMS7
APALPPESSMESLTL	LRRC37A	261	A6NMS7
EMPSEDSLAEPVPTS	NCKAP5L	1096	Q9HCH0
TSEMLPDSDPAPAVT	ELF4	116	Q99607
PPTESRMSVSSDPDP	MAPK8IP1	301	Q9UQF2
STEESSPQDQPPVMR	INPP4B	491	O15327
TDMSTIPPSASLNLP	KIAA1109	3036	Q2LD37
SPPSQSESLLAMFDP	GAPVD1	816	Q14C86
TPEEMSNLTPESSPE	BRSK2	501	Q8IWQ3
PMRSQASEEESPVSP	BSN	3496	Q9UPA5
ADELDDSKPPPSSSM	DAG1	801	Q14118
MALPTPSDSTLPAEA	DUX4L3	1	P0CJ86
EPENMESVPLDPSAS	IGF1R	1296	P08069
SDITELAPASPMASP	HSF1	266	Q00613
DLFSPSVTVPDMSLP	HSF1	416	Q00613
ESLESFSSMPDPVDP	PCM1	1256	Q15154
SAESPPEMDESTCPS	ICAM5	661	Q9UMF0
SSSPVPTLSPEQQEM	NXF1	556	Q9UBU9
VSIDPTMPANSERTP	PDE9A	61	O76083
METLPLESQTHPTSP	FAM205A	866	Q6ZU69
SQMEDPSTSPSPGTR	EVL	296	Q9UI08
SLAGPSSEMETSVPP	NPLOC4	81	Q8TAT6
NTPETTMPPSEATTP	DEFB125	116	Q8N687
EATTPETTMPPSETA	DEFB125	126	Q8N687
PSETATSETMPPPSQ	DEFB125	136	Q8N687
SVLEPSMSSPSDIDS	MPHOSPH9	326	Q99550
NDAETMSVDSSLPSP	POU2F2	266	P09086
IQLDDMSSPPSPEST	PHRF1	1281	Q9P1Y6
TSMSPLEIPSDSEES	KLF8	221	O95600
IEMPTLSSSPTEERP	KDM3B	736	Q7LBC6
FTVNTPPTPEDLMLS	KNL1	1921	Q8NG31
QEAPALPPESSMESL	LRRC37B	301	Q96QE4
LPPESSMESLAQTPL	LRRC37B	306	Q96QE4
PMVPPTSDRSQESSA	KIAA1549L	1371	Q6ZVL6
SQDEDPSLSPDMPIT	FGD3	486	Q5JSP0
MSNPSPQVPEEEAST	NFKBIL1	1	Q9UBC1
SMPTVSFLDQDQSPP	ARHGAP32	1191	A7KAX9
EESPMDVDQPSPSAQ	HUWE1	3806	Q7Z6Z7
PTTDPQASLSPMSES	MSL2	166	Q9HCI7
MELDLSPPHLSSSPE	GRB7	1	Q14451
PPVLSSDPNMLSNEE	NUP155	1001	O75694
SASMPETTATEPQPD	PPP1R37	471	O75864
ESPQNPSSSPLAEMA	NCOA6	1116	Q14686
FDTMSPAPVIPSNTD	TP73	106	O15350
PASLEFLPMESPTAV	ATP13A2	786	Q9NQ11
QPESPVLLPATEMAS	CROCC	61	Q5TZA2
LTSDSPPHNDIMTPV	FOXO1	466	Q12778
MESIPATSEAASPPA	HYDIN	1231	Q4G0P3
SQPEDSVPTPDEVSM	HEATR5B	1846	Q9P2D3
AAATPEPAMAQPDST	CAMKV	456	Q8NCB2
AQPSSSTDPSIMEPT	E2F2	331	Q14209
STDPSIMEPTASSVP	E2F2	336	Q14209
MALPTPSDSTLPAEA	DUX4L9	1	Q6RFH8
PPSSSSQDEELLMPP	TMEM63B	796	Q5T3F8
SSDMSLSEPPQPLAR	CEP350	711	Q5VT06
TPTPTEAAPMPETSE	COL5A1	311	P20908
MALPTPSDSTLPAEA	DUX4L7	1	P0CJ90
LISTPPSDMLPTTEG	BTBD7	541	Q9P203
STSVMSNLPPPVDHE	DNAJC13	2221	O75165
EESEPMDTSPIPTSP	ELF2	151	Q15723
MDTSPIPTSPDSHEP	ELF2	156	Q15723
MPPDSSSPENKSLEV	IRAK4	146	Q9NWZ3
MALPTPSDSTLPAEA	DUX4L5	1	P0CJ88
VTVPDPSPTSEEMTD	GTF2IRD1	506	Q9UHL9
EESATVSAPAPMSPT	SCNM1	171	Q9BWG6
SDMAVSTPASEPQPD	PERM1	296	Q5SV97
STPASEPQPDRDMAV	PERM1	301	Q5SV97
EPQPDRDMAVSTPAS	PERM1	306	Q5SV97
RDMAVSTPASEPQPD	PERM1	326	Q5SV97
STPASEPQPDTDMAV	PERM1	331	Q5SV97
EPQPDTDMAVSTPAS	PERM1	336	Q5SV97
TDMAVSTPASEPQPD	PERM1	341	Q5SV97
STPASEPQPDRDMAV	PERM1	346	Q5SV97
QASPMPVDSVEADPT	PPRC1	581	Q5VV67
MDPTPEASEPSTSQG	KRBA2	471	Q6ZNG9
LPQTMEPSPSETSLV	MTMR3	876	Q13615
LSSQLPDTPNSMVPS	ISL2	341	Q96A47
VEMDPSTEATSPPTT	MUC3B	701	Q9H195
PVMVPDSAVASDNSP	HSFX1	276	Q9UBD0
STPLMLAPDSGELSP	RTL9	191	Q8NET4
SSDPEVLTLSMAVPP	TRIM34	416	Q9BYJ4
SSNEPENRVLPMPTS	TRIM36	651	Q9NQ86
ENPPSNMSPDTLALF	SLFN14	751	P0C7P3
PLSSLLPSASVPESM	SNX29	451	Q8TEQ0
ASPPNTDELMSRSQP	TAB2	371	Q9NYJ8
AETPSDPQTETLSAM	MTF1	701	Q14872
VNPMDSTVTPAPSDA	NCAN	826	O14594
SDIEEMTDSSLPSSP	NAV2	1856	Q8IVL1
RTTPTMSEEPPLDLT	SIPA1L3	1701	O60292
PLMSSSEEEFSPPQS	SIX1	211	Q15475
EDTGLSMPSDTSLSP	SECISBP2L	621	Q93073
DMPLEEPSSSSVPSA	SRCAP	2211	Q6ZRS2
TTSMPAPTTTTPEEE	SSC5D	1551	A1L4H1
TPEPTEMQSPSTREI	PROB1	556	E7EW31
DFLSLPIMVPPDTST	NPAP1	791	Q9NZP6
TAILDHPPSPMDTSE	MRTFA	851	Q969V6
LQMPESEGPSSLDPS	SQSTM1	356	Q13501
DSAEQLSSPMPSATP	SHANK2	1136	Q9UPX8
PSLELESTSETSDMP	SSH3	546	Q8TE77
SDSDKSTEDPPMDLP	BRPF1	956	P55201
PPMQLDSTSAEDTSP	CD300LG	216	Q6UXG3
FPSNPSLMDSENPSD	CHST15	116	Q7LFX5
TSQEDPKESPAMLPT	NCAPD2	906	Q15021
PSSTPITPAMPLDED	ZNF532	731	Q9HCE3
APRETPSEMATNSLP	TTBK1	1001	Q5TCY1
DMLTPTPDSSPRSTS	REV3L	1846	O60673
SQDPERSSPPMLSAD	SRCIN1	6	Q9C0H9
PSTLNPTMPASERTV	SYNGAP1	1141	Q96PV0
IPLPMEDSISTQPSD	TASL	161	Q9HAI6
DPAGEETMSPTSPTL	TRPM3	1341	Q9HCF6
DSSPPEVSGPSSSQM	ZC3H11A	736	O75152
TPAAEETMNTSPGTP	TNFRSF10C	161	O14798
PSAMAELPPSANTSV	TMEM116	66	Q8NCL8
SEPNPDDPLMADISS	UBE2T	116	Q9NPD8
THDMEPSTPDTPKES	SUCO	561	Q9UBS9
AAMSLQEEAEPTPSP	ZNF469	2016	Q96JG9
VDPPSLMATSDPPQS	ZXDA	656	P98168
MSSEVGSTASDEPPP	PHLPP1	1486	O60346
PMDIVPPSEDSNSQD	PNISR	116	Q8TF01
NMTPSDPLQTSLSPE	ZBTB2	191	Q8N680
PPNTLMELSLEPADS	TMEM72	201	A0PK05
PVEPISNSEPSMNSD	VEZT	621	Q9HBM0
ESPEMTSLPPATLEA	VRTN	141	Q9H8Y1
SMPDDVFESPPLSAS	RHBDF2	301	Q6PJF5
TSTEPMDPLTPSAAA	PPP6R3	746	Q5H9R7
TSLESMPASGEPEPS	ZZZ3	341	Q8IYH5
ESILEPPAMAAPESS	SON	1341	P18583
LEETPEAPVPTNMST	TNS2	1251	Q63HR2
TVESSPERPMNNSPE	TOX4	511	O94842
ISPSSRNPASVEPTM	WDR81	1521	Q562E7
EDSSPSLLLSMTVPP	TRIM6	416	Q9C030
SEDFSPLSPDVPMTV	ZFYVE16	896	Q7Z3T8
PSLPTPDMSSEVLED	ZNF541	56	Q9H0D2
PTTPTEETTTSMEEP	ZAN	661	Q9Y493
TTASPETPELDMAAP	WFIKKN2	196	Q8TEU8
MALPTPSDSTLPAEA	DUX4L2	1	P0CJ85
AEPLSPAMSISPQAT	KIAA1522	276	Q9P206
AMTPPLPLQDTDLSS	NACAD	601	O15069
AMTPPLPLQDTDLSS	NACAD	681	O15069
AMTPPLPLQDTDLSS	NACAD	721	O15069
AMTPPLPLQDTDLSS	NACAD	761	O15069
AMTPPLPLQDTDLSS	NACAD	801	O15069
AMTPPLPLQDTDLSS	NACAD	841	O15069
AMTPPLPLQDTDLSS	NACAD	881	O15069