Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	RNA splicing	DDX23 SREK1 SRSF4 SFSWAP SRRM2 RRP1B CLK1 PRPF40A LUC7L2 SRRM4 SON ZRANB2	1.90e-11	502	35	12	GO:0008380
GeneOntologyBiologicalProcess	mRNA processing	DDX23 SREK1 PDE12 SRSF4 SFSWAP SRRM2 RRP1B PRPF40A LUC7L2 SRRM4 SON ZRANB2	5.59e-11	551	35	12	GO:0006397
GeneOntologyBiologicalProcess	mRNA metabolic process	DDX23 SREK1 PDE12 SRSF4 SFSWAP SRRM2 RRP1B PRPF40A LUC7L2 SRRM4 SON ZRANB2	1.80e-08	917	35	12	GO:0016071
GeneOntologyBiologicalProcess	RNA processing	DDX23 DDX56 SREK1 PDE12 SRSF4 SFSWAP SRRM2 RRP1B CLK1 PRPF40A LUC7L2 SRRM4 SON ZRANB2	5.90e-08	1500	35	14	GO:0006396
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	DDX23 SRSF4 SFSWAP SRRM2 PRPF40A LUC7L2 SRRM4 SON	1.19e-07	358	35	8	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	DDX23 SRSF4 SFSWAP SRRM2 PRPF40A LUC7L2 SRRM4 SON	1.19e-07	358	35	8	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	DDX23 SRSF4 SFSWAP SRRM2 PRPF40A LUC7L2 SRRM4 SON	1.30e-07	362	35	8	GO:0000375
GeneOntologyBiologicalProcess	regulation of RNA splicing	SRSF4 SFSWAP RRP1B CLK1 SRRM4 SON	1.21e-06	207	35	6	GO:0043484
GeneOntologyBiologicalProcess	regulation of timing of anagen	FERMT1 SPINK5	4.18e-05	6	35	2	GO:0051884
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	SRSF4 SFSWAP SRRM4 SON	6.58e-05	129	35	4	GO:0048024
GeneOntologyBiologicalProcess	mRNA cis splicing, via spliceosome	DDX23 SFSWAP PRPF40A	6.90e-05	47	35	3	GO:0045292
GeneOntologyBiologicalProcess	regulation of hair follicle maturation	FERMT1 SPINK5	1.25e-04	10	35	2	GO:0048819
GeneOntologyBiologicalProcess	regulation of mRNA processing	SRSF4 SFSWAP SRRM4 SON	1.44e-04	158	35	4	GO:0050684
GeneOntologyBiologicalProcess	anagen	FERMT1 SPINK5	3.31e-04	16	35	2	GO:0042640
GeneOntologyBiologicalProcess	mitotic chromosome condensation	NUSAP1 NCAPD2	4.70e-04	19	35	2	GO:0007076
GeneOntologyBiologicalProcess	spliceosomal complex assembly	DDX23 SFSWAP LUC7L2	6.28e-04	99	35	3	GO:0000245
GeneOntologyBiologicalProcess	hair cycle phase	FERMT1 SPINK5	6.92e-04	23	35	2	GO:0044851
GeneOntologyBiologicalProcess	regulation of mRNA metabolic process	PDE12 SRSF4 SFSWAP SRRM4 SON	8.53e-04	443	35	5	GO:1903311
GeneOntologyBiologicalProcess	negative regulation of mRNA splicing, via spliceosome	SRSF4 SFSWAP	1.03e-03	28	35	2	GO:0048025
GeneOntologyBiologicalProcess	hair follicle maturation	FERMT1 SPINK5	1.10e-03	29	35	2	GO:0048820
GeneOntologyBiologicalProcess	negative regulation of mRNA processing	SRSF4 SFSWAP	1.10e-03	29	35	2	GO:0050686
GeneOntologyBiologicalProcess	negative regulation of RNA splicing	SRSF4 SFSWAP	1.43e-03	33	35	2	GO:0033119
GeneOntologyBiologicalProcess	ribonucleoprotein complex biogenesis	DDX23 DDX56 SFSWAP RRP1B LUC7L2	1.66e-03	515	35	5	GO:0022613
GeneOntologyCellularComponent	nuclear speck	ZNF106 SREK1 SRSF4 SRRM2 PRPF40A LUC7L2 SON	6.16e-06	431	35	7	GO:0016607
GeneOntologyCellularComponent	spliceosomal complex	DDX23 SREK1 SRRM2 PRPF40A LUC7L2	2.77e-05	215	35	5	GO:0005681
GeneOntologyCellularComponent	nuclear body	ZNF106 GARIN3 SREK1 SRSF4 SRRM2 PRPF40A LUC7L2 SON	9.78e-05	903	35	8	GO:0016604
GeneOntologyCellularComponent	U2-type prespliceosome	PRPF40A LUC7L2	4.10e-04	18	35	2	GO:0071004
GeneOntologyCellularComponent	prespliceosome	PRPF40A LUC7L2	4.10e-04	18	35	2	GO:0071010
GeneOntologyCellularComponent	spliceosomal snRNP complex	DDX23 PRPF40A LUC7L2	5.52e-04	96	35	3	GO:0097525
GeneOntologyCellularComponent	U2-type spliceosomal complex	SRRM2 PRPF40A LUC7L2	5.69e-04	97	35	3	GO:0005684
GeneOntologyCellularComponent	ribonucleoprotein complex	DDX23 SREK1 SRSF4 SRRM2 RRP1B RPL3 PRPF40A LUC7L2	6.53e-04	1194	35	8	GO:1990904
GeneOntologyCellularComponent	small nuclear ribonucleoprotein complex	DDX23 PRPF40A LUC7L2	7.57e-04	107	35	3	GO:0030532
GeneOntologyCellularComponent	Sm-like protein family complex	DDX23 PRPF40A LUC7L2	1.03e-03	119	35	3	GO:0120114
GeneOntologyCellularComponent	U1 snRNP	PRPF40A LUC7L2	1.39e-03	33	35	2	GO:0005685
Domain	RNA_helicase_DEAD_Q_motif	DDX23 DDX56	2.43e-03	37	37	2	IPR014014
Domain	Q_MOTIF	DDX23 DDX56	2.43e-03	37	37	2	PS51195
Domain	DEAD	DDX23 DDX56	9.19e-03	73	37	2	PF00270
Domain	DEAD/DEAH_box_helicase_dom	DDX23 DDX56	9.19e-03	73	37	2	IPR011545
Pathway	WP_MRNA_PROCESSING	DDX56 SREK1 SRSF4 SFSWAP CLK1 PRPF40A SON BRWD1	3.31e-07	451	23	8	MM15946
Pathway	WP_MRNA_PROCESSING	SREK1 SRSF4 SFSWAP CLK1 PRPF40A	1.56e-06	126	23	5	M39406
Pathway	REACTOME_MRNA_SPLICING	DDX23 SRSF4 SRRM2 PRPF40A	3.52e-04	212	23	4	M14033
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	DDX23 SRSF4 SRRM2 PRPF40A	1.04e-03	283	23	4	M13087
Pathway	KEGG_SPLICEOSOME	DDX23 SRSF4 PRPF40A	1.11e-03	127	23	3	M2044
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	NUSAP1 SMARCC1 DDX23 DIDO1 ZNF106 DDX56 SREK1 SFSWAP SRRM2 RRP1B RPL3 PRPF40A LUC7L2 SON ZRANB2	4.86e-14	989	38	15	36424410
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NUSAP1 SMARCC1 DDX23 DIDO1 ZNF106 DDX56 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 SON BCORL1	1.26e-13	1294	38	16	30804502
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SMARCC1 DDX23 DIDO1 DDX56 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 CLK1 PRPF40A LUC7L2 SON ZRANB2	1.78e-13	1082	38	15	38697112
Pubmed	The protein interaction landscape of the human CMGC kinase group.	DDX23 DIDO1 SREK1 SRSF4 SRRM2 RRP1B ARGLU1 CLK1 PRPF40A LUC7L2 SON ZRANB2	6.22e-12	695	38	12	23602568
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	DDX23 DDX56 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 PRPF40A SON ZRANB2	8.36e-12	713	38	12	29802200
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	DDX23 DDX56 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 SON ZRANB2	1.12e-11	731	38	12	29298432
Pubmed	The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.	SREK1 SRSF4 SFSWAP ARGLU1 PRPF40A LUC7L2 SON	2.04e-11	104	38	7	31365120
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SMARCC1 DDX23 DIDO1 DDX56 SRSF4 SRRM2 RRP1B RPL3 PRPF40A SON NCAPD2	7.14e-11	653	38	11	22586326
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	NUSAP1 DDX23 SREK1 SRSF4 SFSWAP RPL3 CLK1 PRPF40A LUC7L2 SRRM4 ZRANB2	2.10e-10	723	38	11	34133714
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	DDX56 SRSF4 SRRM2 ARGLU1 RPL3 LUC7L2 SON ZRANB2	3.42e-10	259	38	8	30404004
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	DDX23 DIDO1 SREK1 SRSF4 SRRM2 RRP1B RPL3 PRPF40A LUC7L2 SON ZRANB2	6.67e-10	807	38	11	22681889
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SMARCC1 DDX23 DIDO1 DDX56 SREK1 SRSF4 SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 SON	7.02e-10	1318	38	13	30463901
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	DDX56 SREK1 SRSF4 SFSWAP SRRM2 RRP1B RPL3 PRPF40A LUC7L2 SON ZRANB2	1.11e-09	847	38	11	35850772
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	DDX23 SREK1 FAM193A SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 ZRANB2	1.54e-09	655	38	10	35819319
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SMARCC1 DIDO1 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 PRPF40A SON BCORL1	3.82e-09	954	38	11	36373674
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	SMARCC1 DDX23 DDX56 SREK1 SRSF4 SFSWAP SRRM2 RPL3 PRPF40A LUC7L2 SON ZRANB2	6.78e-09	1284	38	12	17353931
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DDX23 SREK1 SRSF4 SRRM2 ARGLU1 PRPF40A LUC7L2 FERMT1 NCAPD2	1.02e-08	582	38	9	20467437
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	SMARCC1 DDX23 DDX56 SFSWAP SRRM2 RRP1B RPL3 PRPF40A LUC7L2	1.43e-08	605	38	9	28977666
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SMARCC1 DDX56 SREK1 SFSWAP SRRM2 LBX1 ARGLU1 PRPF40A LUC7L2 SON BRWD1	1.92e-08	1116	38	11	31753913
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	SMARCC1 DDX56 SREK1 FAM193A SRSF4 RRP1B RPL3 LUC7L2 SON	3.79e-08	678	38	9	30209976
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	SMARCC1 DDX56 SRSF4 SRRM2 RPL3 PRPF40A LUC7L2 ZRANB2	4.65e-08	486	38	8	30940648
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	SMARCC1 DDX23 DDX56 SRSF4 SRRM2 RRP1B RPL3	4.74e-08	316	38	7	31665637
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	NUSAP1 DDX23 DDX56 SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 SON	5.16e-08	949	38	10	36574265
Pubmed	Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer.	SREK1 SRRM2 ARGLU1 RPL3 PRPF40A LUC7L2	9.46e-08	206	38	6	34185411
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SMARCC1 DIDO1 ZNF106 SFSWAP SRRM2 ARGLU1 PRPF40A SON ZRANB2	1.17e-07	774	38	9	15302935
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRSF4 SRRM2 RRP1B RPL3 PRPF40A MYPN SON	1.17e-07	361	38	7	30344098
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	DDX23 SRSF4 SRRM2 ARGLU1 PRPF40A	1.67e-07	115	38	5	17332742
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	SMARCC1 SREK1 SRSF4 SRRM2 RRP1B RPL3 PRPF40A LUC7L2 NCAPD2	1.70e-07	809	38	9	32129710
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SMARCC1 DDX23 DIDO1 SRRM2 RRP1B RPL3 LUC7L2 SON SPINK5 NCAPD2 ZRANB2	2.12e-07	1415	38	11	28515276
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SMARCC1 DDX56 SREK1 PDE12 SRRM2 RRP1B RPL3 PRPF40A LUC7L2 NCAPD2 ZRANB2	2.28e-07	1425	38	11	30948266
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SMARCC1 DDX23 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 BRWD1 NCAPD2	2.50e-07	847	38	9	35235311
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	NUSAP1 SMARCC1 SRRM2 RRP1B PRPF40A LUC7L2 SON	2.81e-07	411	38	7	35182466
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SMARCC1 DDX23 SRSF4 SFSWAP ARGLU1 ZRANB2	3.03e-07	251	38	6	31076518
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	NUSAP1 DIDO1 DDX56 PDE12 RRP1B RPL3 PRPF40A SON	3.12e-07	624	38	8	33729478
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PLEKHG1 DDX23 SREK1 PDE12 FAM193A SRRM2 RRP1B ARGLU1 RPL3 PRPF40A ZRANB2	3.48e-07	1487	38	11	33957083
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	SREK1 SRSF4 SFSWAP ARGLU1 PRPF40A LUC7L2	4.54e-07	269	38	6	29511261
Pubmed	The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.	SMARCC1 SFSWAP PRPF40A LUC7L2	4.59e-07	57	38	4	21555454
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	DDX23 SREK1 SRSF4 SRRM2 RPL3 LUC7L2	8.58e-07	300	38	6	28561026
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	SRRM2 RRP1B PRPF40A NCAPD2 ZRANB2	9.42e-07	163	38	5	22113938
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	SMARCC1 DDX23 SRRM2 RPL3 PRPF40A SON ZRANB2	1.13e-06	506	38	7	30890647
Pubmed	SON and SRRM2 are essential for nuclear speckle formation.	SRRM2 SON	1.16e-06	2	38	2	33095160
Pubmed	Characterization of a disease-associated mutation affecting a putative splicing regulatory element in intron 6b of the cystic fibrosis transmembrane conductance regulator (CFTR) gene.	SRSF4 CFTR	1.16e-06	2	38	2	19759008
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NUSAP1 SMARCC1 DDX23 DIDO1 DDX56 SFSWAP RRP1B PRPF40A LUC7L2 SON	1.51e-06	1371	38	10	36244648
Pubmed	Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.	SMARCC1 SRSF4 SRRM2 PRPF40A SON	1.53e-06	180	38	5	30110629
Pubmed	Tagging genes with cassette-exchange sites.	NUSAP1 SMARCC1 DIDO1 DDX56 SFSWAP PRPF40A	1.63e-06	335	38	6	15741177
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NUSAP1 DIDO1 DDX56 SREK1 SFSWAP RRP1B ARGLU1 SON NCAPD2 ZRANB2	3.32e-06	1497	38	10	31527615
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	SMARCC1 DDX23 DIDO1 PRPF40A SON	4.10e-06	220	38	5	35785414
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	SMARCC1 PDE12 SFSWAP SRRM2 PRPF40A SON	4.44e-06	399	38	6	35987950
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	DIDO1 ZNF106 DDX56 SRSF4 SON FERMT1	5.19e-06	410	38	6	26949251
Pubmed	Nucleolar proteome dynamics.	DDX23 ZNF106 DDX56 RRP1B RPL3 LUC7L2	5.88e-06	419	38	6	15635413
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	SMARCC1 SFSWAP ARGLU1 PRPF40A BCORL1 ZRANB2	6.37e-06	425	38	6	24999758
Pubmed	Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.	DDX23 SRSF4 RPL3 PRPF40A LUC7L2	6.38e-06	241	38	5	23125841
Pubmed	Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells.	SRSF4 SRRM2	6.96e-06	4	38	2	14578391
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	DDX23 RPL3 PRPF40A SON	7.42e-06	114	38	4	31553912
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	SRSF4 RRP1B RPL3 SON NCAPD2	8.08e-06	253	38	5	29911972
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	SRRM2 CLK1 PRPF40A LUC7L2 SON	8.39e-06	255	38	5	15324660
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	DDX23 SRSF4 SRRM2 RPL3 CLK1 PRPF40A SON	1.08e-05	714	38	7	28302793
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NUSAP1 SMARCC1 DDX23 DIDO1 ARGLU1 PRPF40A SON NCAPD2	1.14e-05	1014	38	8	32416067
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SMARCC1 DDX23 DDX56 PDE12 SRRM2 RPL3 SON FERMT1 NCAPD2	1.17e-05	1353	38	9	29467282
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DDX23 DDX56 SRRM2 RRP1B ARGLU1 RPL3 PRPF40A SON	1.23e-05	1024	38	8	24711643
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	DIDO1 SRRM2 PRPF40A SON	1.25e-05	130	38	4	35545047
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DIDO1 SRRM2 RRP1B MYPN SON NCAPD2	1.66e-05	503	38	6	16964243
Pubmed	A coactivator of pre-mRNA splicing.	SRSF4 SRRM2	1.74e-05	6	38	2	9531537
Pubmed	The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.	SRSF4 CLK1	1.74e-05	6	38	2	8617202
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	SMARCC1 DDX23 SRRM2 RRP1B RPL3 PRPF40A	2.29e-05	533	38	6	30554943
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	SMARCC1 DDX23 SRRM2 PRPF40A	2.43e-05	154	38	4	16055720
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DDX56 PDE12 SRSF4 SRRM2 RRP1B ARGLU1 RPL3 LUC7L2 SON	2.59e-05	1496	38	9	32877691
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	RRP1B RPL3 PRPF40A LUC7L2 SON	3.34e-05	340	38	5	29478914
Pubmed	Regulation of alternative splicing by SRrp86 and its interacting proteins.	SREK1 SRSF4 ZRANB2	3.38e-05	57	38	3	14559993
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	DDX23 DIDO1 DDX56 SRRM2 NCAPD2	3.39e-05	341	38	5	32971831
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	SRSF4 SRRM2 RPL3 SON	3.49e-05	169	38	4	23084401
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	SMARCC1 SRSF4 SRRM2 PRPF40A	3.57e-05	170	38	4	16159877
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SMARCC1 ZNF106 SRRM2 RRP1B RPL3 CLK1 PRPF40A NCAPD2	3.88e-05	1203	38	8	29180619
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	DIDO1 SRRM2 RRP1B CLK1 SON	4.44e-05	361	38	5	26167880
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	NUSAP1 SMARCC1 DIDO1 RRP1B BCORL1 BRWD1	4.78e-05	608	38	6	36089195
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	PLEKHG1 ZNF106 GARIN3 MYRFL SRSF4 CLK1 SRRM4 ZRANB2	4.87e-05	1242	38	8	30973865
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SMARCC1 SRSF4 SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2	5.01e-05	1247	38	8	27684187
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	SRSF4 SRRM2 ARGLU1 PRPF40A	6.34e-05	197	38	4	22365833
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	DIDO1 GARIN3 ARGLU1 BCORL1 NCAPD2	6.88e-05	396	38	5	26687479
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	DDX23 DIDO1 SRRM2 RPL3 PRPF40A SON	7.03e-05	652	38	6	31180492
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	ZNF106 SRSF4 CLK1 LUC7L2	7.12e-05	203	38	4	35012549
Pubmed	A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.	CLK1 PRPF40A LUC7L2	7.70e-05	75	38	3	15383276
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	SRRM2 RPL3 SON	8.01e-05	76	38	3	27542412
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	SRRM2 RRP1B SON NCAPD2	8.12e-05	210	38	4	16565220
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DDX23 SRSF4 SRRM2 PRPF40A LUC7L2 NCAPD2	8.16e-05	670	38	6	22990118
Pubmed	A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).	SRSF4 SFSWAP	9.00e-05	13	38	2	20516191
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	SMARCC1 SREK1 PDE12 RRP1B PRPF40A SON NCAPD2 ZRANB2	9.52e-05	1367	38	8	32687490
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	DDX23 SRRM2 ARGLU1 BRWD1 NCAPD2	1.02e-04	431	38	5	33660365
Pubmed	Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.	NUSAP1 DDX56 RRP1B RPL3 LUC7L2 ZRANB2	1.07e-04	704	38	6	32994395
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	DDX23 RRP1B RPL3 PRPF40A ZRANB2	1.14e-04	441	38	5	31239290
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SMARCC1 SRSF4 SRRM2 PRPF40A	1.23e-04	234	38	4	36243803
Pubmed	Human transcription factor protein interaction networks.	NUSAP1 SMARCC1 DIDO1 DDX56 SRRM2 RRP1B PRPF40A BCORL1	1.29e-04	1429	38	8	35140242
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	NUSAP1 SRSF4 SRRM2 SON	1.34e-04	239	38	4	26641092
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	DDX56 SRSF4 RRP1B RPL3	1.47e-04	245	38	4	35652658
Pubmed	Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations.	DDX23 SRSF4 SRRM2	1.60e-04	96	38	3	25948554
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NUSAP1 SMARCC1 DDX23 DIDO1 SRRM2 BCORL1 ZRANB2	1.69e-04	1103	38	7	34189442
Pubmed	BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing.	SRSF4 SRRM2	1.96e-04	19	38	2	25263594
Pubmed	Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource.	ZNF106 SRRM4	1.96e-04	19	38	2	23912999
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	DDX23 ZNF106 SREK1 LUC7L2 NCAPD2	1.99e-04	497	38	5	36774506
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SRSF4 SRRM2 RPL3 PRPF40A LUC7L2 NCAPD2 ZRANB2	2.17e-04	1149	38	7	35446349
Interaction	SRSF11 interactions	DDX23 SREK1 SRSF4 SRRM2 ARGLU1 CLK1 PRPF40A LUC7L2 SRRM4 SON ZRANB2	7.83e-14	203	38	11	int:SRSF11
Interaction	SRPK2 interactions	DDX23 DIDO1 DDX56 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 CLK1 PRPF40A LUC7L2 SON ZRANB2	1.16e-12	717	38	15	int:SRPK2
Interaction	SRSF1 interactions	SMARCC1 DIDO1 DDX56 SREK1 SRSF4 SRRM2 RRP1B ARGLU1 RPL3 CLK1 PRPF40A LUC7L2 SON	1.83e-11	570	38	13	int:SRSF1
Interaction	MECP2 interactions	NUSAP1 SMARCC1 DDX23 DIDO1 DDX56 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 CLK1 PRPF40A LUC7L2 SON ZRANB2	3.51e-11	1287	38	17	int:MECP2
Interaction	SRPK1 interactions	DDX23 SREK1 SRSF4 SRRM2 RRP1B ARGLU1 RPL3 CLK1 LUC7L2 SON FERMT1 ZRANB2	4.17e-11	477	38	12	int:SRPK1
Interaction	SNRNP70 interactions	SMARCC1 DDX23 DDX56 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 SRRM4 SON ZRANB2	1.03e-10	984	38	15	int:SNRNP70
Interaction	DHX8 interactions	DDX23 SRSF4 SFSWAP SRRM2 RPL3 PRPF40A LUC7L2 MYPN SON ZRANB2	1.16e-10	292	38	10	int:DHX8
Interaction	SRSF7 interactions	DDX23 DIDO1 SREK1 SRSF4 SRRM2 ARGLU1 CLK1 PRPF40A LUC7L2 SON ZRANB2	2.33e-10	425	38	11	int:SRSF7
Interaction	RNPS1 interactions	DDX23 SREK1 SRSF4 SFSWAP SRRM2 RPL3 CLK1 PRPF40A LUC7L2 SRRM4 SON	2.33e-10	425	38	11	int:RNPS1
Interaction	U2AF1 interactions	DDX23 DIDO1 DDX56 SRRM2 PRPF40A LUC7L2 SRRM4 SON ZRANB2	4.82e-10	239	38	9	int:U2AF1
Interaction	DDX23 interactions	DDX23 DDX56 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 CLK1 PRPF40A ZRANB2	8.41e-10	480	38	11	int:DDX23
Interaction	MYCN interactions	NUSAP1 SMARCC1 DDX23 DIDO1 ZNF106 C1orf167 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 SON ZRANB2	1.05e-09	1373	38	16	int:MYCN
Interaction	SREK1 interactions	DDX23 SREK1 SRSF4 RPL3 PRPF40A LUC7L2 SRRM4 ZRANB2	1.54e-09	183	38	8	int:SREK1
Interaction	SRPK3 interactions	DDX56 SREK1 SRSF4 SRRM2 RRP1B RPL3 LUC7L2 SON	2.07e-09	190	38	8	int:SRPK3
Interaction	ZC3H18 interactions	DDX23 DDX56 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 RPL3 CLK1 PRPF40A LUC7L2 SON ZRANB2	3.62e-09	877	38	13	int:ZC3H18
Interaction	SNIP1 interactions	DDX56 SRSF4 SRRM2 ARGLU1 RPL3 PRPF40A LUC7L2 SRRM4 SON ZRANB2	3.64e-09	417	38	10	int:SNIP1
Interaction	PNN interactions	DDX23 SREK1 SRSF4 SFSWAP SRRM2 ARGLU1 CLK1 PRPF40A LUC7L2	3.77e-09	302	38	9	int:PNN
Interaction	SRRM4 interactions	SREK1 SRSF4 CLK1 LUC7L2 SRRM4	7.56e-09	37	38	5	int:SRRM4
Interaction	PRP4K interactions	DDX23 SRSF4 SRRM2 RRP1B RPL3 CLK1 PRPF40A LUC7L2 ZRANB2	7.94e-09	329	38	9	int:PRP4K
Interaction	ZCCHC10 interactions	SREK1 SFSWAP SRRM2 ARGLU1 PRPF40A LUC7L2 SON BCORL1	1.13e-08	236	38	8	int:ZCCHC10
Interaction	RRS1 interactions	DDX23 DIDO1 DDX56 SREK1 SRSF4 RRP1B RPL3 PRPF40A CFTR	1.20e-08	345	38	9	int:RRS1
Interaction	CFAP20 interactions	SFSWAP SRRM2 PRPF40A LUC7L2 CFTR ZRANB2	1.76e-08	91	38	6	int:CFAP20
Interaction	SRSF6 interactions	DDX23 DDX56 SREK1 SRSF4 SRRM2 RRP1B RPL3 CLK1 LUC7L2 SON	2.17e-08	503	38	10	int:SRSF6
Interaction	UBR5 interactions	DDX23 SREK1 SRSF4 SFSWAP RRP1B ARGLU1 PRPF40A LUC7L2 CFTR SON	3.74e-08	533	38	10	int:UBR5
Interaction	IFI6 interactions	DIDO1 SREK1 SFSWAP ARGLU1 PRPF40A	5.36e-08	54	38	5	int:IFI6
Interaction	SRSF4 interactions	DDX23 SREK1 SRSF4 SRRM2 ARGLU1 CLK1 SRRM4 SON	7.29e-08	300	38	8	int:SRSF4
Interaction	ACIN1 interactions	DDX23 SRSF4 SRRM2 ARGLU1 PRPF40A LUC7L2 SON ZRANB2	7.48e-08	301	38	8	int:ACIN1
Interaction	SIRT7 interactions	SMARCC1 DDX23 DIDO1 DDX56 SRSF4 SRRM2 RRP1B RPL3 PRPF40A SON NCAPD2	7.80e-08	744	38	11	int:SIRT7
Interaction	JMJD6 interactions	DIDO1 SREK1 SFSWAP ARGLU1 PRPF40A LUC7L2 SON	9.83e-08	205	38	7	int:JMJD6
Interaction	RBM25 interactions	SMARCC1 DDX23 DDX56 SREK1 SRRM2 PRPF40A SRRM4 CFTR	1.29e-07	323	38	8	int:RBM25
Interaction	IFI27L1 interactions	DIDO1 SREK1 SFSWAP ARGLU1 PRPF40A	1.38e-07	65	38	5	int:IFI27L1
Interaction	PIP4K2A interactions	NUSAP1 DDX23 DDX56 SRRM2 RRP1B LUC7L2 ZRANB2	1.40e-07	216	38	7	int:PIP4K2A
Interaction	SRRM2 interactions	SMARCC1 DDX23 SRSF4 SRRM2 CLK1 PRPF40A LUC7L2 SON ZRANB2	1.46e-07	462	38	9	int:SRRM2
Interaction	SNRNP40 interactions	SMARCC1 DDX23 DDX56 SREK1 SFSWAP SRRM2 RRP1B RPL3 PRPF40A SON	1.97e-07	637	38	10	int:SNRNP40
Interaction	MEN1 interactions	DDX23 DIDO1 DDX56 SREK1 SRSF4 SRRM2 RRP1B RPL3 PRPF40A CFTR SON NCAPD2	2.32e-07	1029	38	12	int:MEN1
Interaction	BRD3 interactions	SMARCC1 SREK1 SFSWAP SRRM2 RRP1B ARGLU1 PRPF40A LUC7L2 SON	2.57e-07	494	38	9	int:BRD3
Interaction	RC3H1 interactions	SMARCC1 DDX56 SREK1 FAM193A SRSF4 SRRM2 RRP1B RPL3 LUC7L2 ZRANB2	3.46e-07	677	38	10	int:RC3H1
Interaction	RNF113A interactions	DDX23 SREK1 FAM193A SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 ZRANB2	4.23e-07	692	38	10	int:RNF113A
Interaction	TOP1 interactions	SMARCC1 DDX23 DIDO1 DDX56 SRRM2 RRP1B PRPF40A CFTR SON ZRANB2	4.46e-07	696	38	10	int:TOP1
Interaction	SFPQ interactions	SMARCC1 DDX23 DIDO1 SREK1 SRSF4 SRRM2 PRPF40A CFTR SON	7.69e-07	563	38	9	int:SFPQ
Interaction	NR2C2 interactions	SMARCC1 DDX23 DIDO1 DDX56 SREK1 SRSF4 SRRM2 RRP1B ARGLU1 RPL3 PRPF40A LUC7L2 SON	8.92e-07	1403	38	13	int:NR2C2
Interaction	AKAP17A interactions	DDX23 SRSF4 SRRM2 SRRM4 ZRANB2	1.14e-06	99	38	5	int:AKAP17A
Interaction	SNRPC interactions	DDX23 DIDO1 SREK1 SRSF4 SRRM2 ARGLU1 PRPF40A SON	1.33e-06	440	38	8	int:SNRPC
Interaction	C1orf35 interactions	DDX56 SRRM2 RRP1B PRPF40A LUC7L2 SRRM4 CFTR	1.40e-06	304	38	7	int:C1orf35
Interaction	SAP18 interactions	SMARCC1 DDX23 SREK1 SRRM2 ARGLU1 PRPF40A SON	1.43e-06	305	38	7	int:SAP18
Interaction	SMC5 interactions	SMARCC1 DIDO1 SREK1 SRSF4 SFSWAP SRRM2 RRP1B ARGLU1 PRPF40A SON BCORL1	1.49e-06	1000	38	11	int:SMC5
Interaction	DOT1L interactions	DDX56 SRSF4 SFSWAP SRRM2 RRP1B RPL3 PRPF40A LUC7L2 SON ZRANB2	1.71e-06	807	38	10	int:DOT1L
Interaction	NUP43 interactions	SMARCC1 SREK1 SRRM2 RRP1B SZT2 ARGLU1 RPL3 LUC7L2 SON	1.83e-06	625	38	9	int:NUP43
Interaction	RBM39 interactions	DDX23 SREK1 SRSF4 SRRM2 RPL3 CLK1 PRPF40A LUC7L2 SRRM4 CFTR SON	2.22e-06	1042	38	11	int:RBM39
Interaction	U2AF2 interactions	NUSAP1 DDX23 SRSF4 SRRM2 CLK1 PRPF40A LUC7L2 SON ZRANB2	2.55e-06	651	38	9	int:U2AF2
Interaction	CDC5L interactions	DDX23 SREK1 SRSF4 SRRM2 ARGLU1 RPL3 PRPF40A SON FERMT1 NCAPD2	2.87e-06	855	38	10	int:CDC5L
Interaction	RC3H2 interactions	SMARCC1 DDX56 SREK1 FAM193A SRSF4 RRP1B RPL3 LUC7L2 SON	3.11e-06	667	38	9	int:RC3H2
Interaction	PARP1 interactions	SMARCC1 DIDO1 ZNF106 DDX56 SREK1 RRP1B RPL3 PRPF40A CFTR BCORL1 NCAPD2 ZRANB2	3.15e-06	1316	38	12	int:PARP1
Interaction	CLK3 interactions	SRSF4 SRRM2 RRP1B ARGLU1 CLK1 LUC7L2	3.26e-06	220	38	6	int:CLK3
Interaction	SRRM1 interactions	DDX23 SRSF4 SRRM2 CLK1 PRPF40A SRRM4 CFTR	3.43e-06	348	38	7	int:SRRM1
Interaction	FOLR1 interactions	SREK1 SRRM2 ARGLU1 RPL3 PRPF40A LUC7L2	3.90e-06	227	38	6	int:FOLR1
Interaction	PUF60 interactions	DDX23 SREK1 SRRM2 ARGLU1 PRPF40A CFTR SON	5.04e-06	369	38	7	int:PUF60
Interaction	IFI16 interactions	SMARCC1 DDX23 DDX56 SRSF4 SRRM2 RRP1B RPL3 PRPF40A SON	5.42e-06	714	38	9	int:IFI16
Interaction	CHD4 interactions	SMARCC1 DDX23 DDX56 SFSWAP SRRM2 RRP1B RPL3 PRPF40A LUC7L2 NCAPD2	6.54e-06	938	38	10	int:CHD4
Interaction	TERF2IP interactions	SMARCC1 DDX23 DIDO1 SREK1 SFSWAP SRRM2 PRPF40A ZRANB2	7.13e-06	552	38	8	int:TERF2IP
Interaction	CHERP interactions	DDX23 SRSF4 SFSWAP ARGLU1 RPL3 PRPF40A	8.88e-06	262	38	6	int:CHERP
Interaction	SRSF10 interactions	DDX23 SREK1 SRSF4 CLK1 PRPF40A LUC7L2	1.08e-05	271	38	6	int:SRSF10
Interaction	PRPF38A interactions	SRSF4 CLK1 PRPF40A LUC7L2 SRRM4	1.24e-05	161	38	5	int:PRPF38A
Interaction	PPIE interactions	SRSF4 SRRM2 RRP1B RPL3 PRPF40A LUC7L2	1.35e-05	282	38	6	int:PPIE
Interaction	NIFK interactions	DDX23 ZNF106 DDX56 SREK1 RRP1B ARGLU1 RPL3	1.39e-05	431	38	7	int:NIFK
Interaction	RPL5 interactions	DDX56 RRP1B ARGLU1 RPL3 CLK1 CFTR SON ZRANB2	1.41e-05	606	38	8	int:RPL5
Interaction	RPL22 interactions	SREK1 PDE12 SRRM2 RRP1B RPL3 LUC7L2 CFTR	1.58e-05	440	38	7	int:RPL22
Interaction	PRPF40A interactions	SMARCC1 DDX23 DDX56 SREK1 SRRM2 PRPF40A SON	1.73e-05	446	38	7	int:PRPF40A
Interaction	ZNF330 interactions	NUSAP1 SMARCC1 ZNF106 DDX56 RRP1B BCORL1 ZRANB2	1.73e-05	446	38	7	int:ZNF330
Interaction	KIF20A interactions	NUSAP1 DIDO1 ZNF106 SFSWAP SRRM2 ARGLU1 RPL3 PRPF40A SON ZRANB2	1.78e-05	1052	38	10	int:KIF20A
Interaction	HNRNPC interactions	PITPNM3 SMARCC1 SREK1 SRSF4 SRRM2 PRPF40A CFTR NCAPD2	1.95e-05	634	38	8	int:HNRNPC
Interaction	BRD7 interactions	SMARCC1 DDX56 SRSF4 SRRM2 RPL3 PRPF40A LUC7L2 ZRANB2	2.01e-05	637	38	8	int:BRD7
Interaction	RAD18 interactions	SMARCC1 DDX23 SRSF4 SFSWAP SRRM2 ARGLU1 ZRANB2	2.02e-05	457	38	7	int:RAD18
Interaction	RPS19 interactions	DDX56 SREK1 SRSF4 SRRM2 RRP1B RPL3 PRPF40A CFTR	2.06e-05	639	38	8	int:RPS19
Interaction	DDX56 interactions	NUSAP1 DDX23 DDX56 RRP1B RPL3 PRPF40A	2.06e-05	304	38	6	int:DDX56
Interaction	PPP1R10 interactions	NUSAP1 DDX56 RRP1B PRPF40A LUC7L2	2.07e-05	179	38	5	int:PPP1R10
Interaction	CUL7 interactions	DDX23 DDX56 SRRM2 RRP1B ARGLU1 RPL3 PRPF40A SON ZRANB2	2.09e-05	845	38	9	int:CUL7
Interaction	CCDC9 interactions	ARGLU1 PRPF40A LUC7L2 CFTR	2.24e-05	88	38	4	int:CCDC9
Interaction	LUC7L3 interactions	DDX23 RRP1B CLK1 LUC7L2 ZRANB2	2.42e-05	185	38	5	int:LUC7L3
Interaction	RRP1B interactions	NUSAP1 DDX23 DDX56 RRP1B RPL3 LUC7L2	2.47e-05	314	38	6	int:RRP1B
Interaction	SRSF5 interactions	DDX56 SREK1 SRSF4 SRRM2 RPL3 CLK1 SON	2.56e-05	474	38	7	int:SRSF5
Interaction	SART1 interactions	DDX23 DDX56 SRSF4 SRRM2 PRPF40A NCAPD2	2.61e-05	317	38	6	int:SART1
Interaction	SNRPA interactions	DDX23 DIDO1 SRSF4 SRRM2 PRPF40A CFTR SON	2.85e-05	482	38	7	int:SNRPA
Interaction	ECT2 interactions	DDX23 DDX56 SREK1 SRRM2 RRP1B ARGLU1 RPL3 SON NCAPD2	3.06e-05	887	38	9	int:ECT2
Interaction	POLR1G interactions	ZNF106 DDX56 SRRM2 RRP1B RPL3 BCORL1 ZRANB2	3.12e-05	489	38	7	int:POLR1G
Interaction	CLK2 interactions	SRSF4 SRRM2 CLK1 LUC7L2 SON	3.12e-05	195	38	5	int:CLK2
Interaction	SSRP1 interactions	SMARCC1 DDX23 DIDO1 SREK1 SRRM2 PRPF40A SON BRWD1	3.39e-05	685	38	8	int:SSRP1
Interaction	SRSF8 interactions	SREK1 SRSF4 CLK1 LUC7L2	3.42e-05	98	38	4	int:SRSF8
Interaction	ZRANB2 interactions	DDX23 SREK1 SRRM2 LUC7L2 ZRANB2	3.44e-05	199	38	5	int:ZRANB2
Interaction	ZC3H10 interactions	DDX56 SRSF4 RRP1B RPL3 PRPF40A	3.52e-05	200	38	5	int:ZC3H10
Interaction	EWSR1 interactions	SMARCC1 DDX23 SRSF4 SFSWAP ARGLU1 PRPF40A CFTR BCORL1 ZRANB2	3.62e-05	906	38	9	int:EWSR1
Interaction	RPL13 interactions	DDX56 SREK1 PDE12 RRP1B RPL3 PRPF40A CFTR SON	3.95e-05	700	38	8	int:RPL13
Interaction	SON interactions	DIDO1 SRSF4 SRRM2 PRPF40A SON	4.25e-05	208	38	5	int:SON
Interaction	SNRPB interactions	DDX23 DIDO1 SRSF4 SRRM2 PRPF40A SON NCAPD2	4.44e-05	517	38	7	int:SNRPB
Interaction	MAGEB2 interactions	DDX56 SREK1 RRP1B RPL3 CFTR ZRANB2	4.47e-05	349	38	6	int:MAGEB2
Interaction	DDX21 interactions	DDX23 SRSF4 SRRM2 RRP1B ARGLU1 RPL3 PRPF40A SON	4.73e-05	718	38	8	int:DDX21
Interaction	LUC7L2 interactions	SREK1 SRRM2 RRP1B LUC7L2 SRRM4 ZRANB2	4.76e-05	353	38	6	int:LUC7L2
Interaction	EED interactions	SMARCC1 DIDO1 DDX56 SRRM2 RRP1B SZT2 ARGLU1 RPL3 PRPF40A SON NCAPD2	4.89e-05	1445	38	11	int:EED
Interaction	CPSF6 interactions	SMARCC1 DDX23 DIDO1 SRRM2 PRPF40A LUC7L2 SON	4.96e-05	526	38	7	int:CPSF6
Interaction	ANKRD50 interactions	DIDO1 SFSWAP ARGLU1 PRPF40A	5.00e-05	108	38	4	int:ANKRD50
Cytoband	15q15.1	NUSAP1 ZNF106	7.04e-04	47	38	2	15q15.1
GeneFamily	DEAD-box helicases	DDX23 DDX56	1.18e-03	42	22	2	499
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG1 FERMT1	2.57e-02	206	22	2	682
GeneFamily	RNA binding motif containing	SREK1 SRSF4	2.73e-02	213	22	2	725
Coexpression	YUAN_ZNF143_PARTNERS	NUSAP1 DIDO1 RRP1B	4.25e-06	22	38	3	M2355
Coexpression	TABULA_MURIS_SENIS_PANCREAS_PANCREATIC_BETA_CELL_AGEING	SRRM2 ARGLU1 CLK1 LUC7L2 SON	1.33e-05	212	38	5	MM3816
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	SREK1 PDE12 SFSWAP CLK1 LUC7L2 SON BRWD1	4.81e-05	680	38	7	M41089
Coexpression	TSUTSUMI_FBXW8_TARGETS	SFSWAP MYPN	7.32e-05	9	38	2	M2187
Coexpression	TSUTSUMI_FBXW8_TARGETS	SFSWAP MYPN	7.32e-05	9	38	2	MM888
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SREK1 SRRM2 ARGLU1 CLK1 SON ZRANB2	1.76e-08	200	38	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SMARCC1 KATNIP SZT2 SON	1.20e-05	166	38	4	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF106 SRRM2 RPL3 CLK1	1.72e-05	182	38	4	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF106 SRRM2 RPL3 CLK1	1.75e-05	183	38	4	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF106 SRRM2 RPL3 CLK1	1.75e-05	183	38	4	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 CLK1 PRPF40A SON	1.91e-05	187	38	4	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 ARGLU1 LUC7L2 SON	2.12e-05	192	38	4	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 ARGLU1 LUC7L2 SON	2.21e-05	194	38	4	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 ARGLU1 LUC7L2 SON	2.21e-05	194	38	4	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SREK1 ARGLU1 CLK1 ZRANB2	2.44e-05	199	38	4	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|megakaryocytic / Lineage and Cell class	SMARCC1 SRRM2 ARGLU1 PRPF40A	2.44e-05	199	38	4	99a65887d3c8a2cde26693dd74404b101bba9d58
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	DDX23 DIDO1 SREK1 SRSF4 SRRM2 LUC7L2 SON	1.29e-08	172	38	7	1072_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	DDX23 DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	3.59e-07	170	38	6	1050_DN
Drug	AC1NRA5C	SREK1 SRSF4 SRRM2 CLK1 CFTR ZRANB2	4.12e-07	174	38	6	CID005287709
Drug	Captopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A	NUSAP1 SMARCC1 SFSWAP SRRM2 PRPF40A SON	4.86e-07	179	38	6	4585_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DDX23 DDX56 SREK1 SRSF4 LUC7L2 FERMT1	5.54e-07	183	38	6	4770_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2 FERMT1	7.78e-06	165	38	5	6085_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	7.78e-06	165	38	5	2835_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2 FERMT1	8.25e-06	167	38	5	5217_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	8.49e-06	168	38	5	6820_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SREK1 SRSF4 CLK1 LUC7L2 FERMT1	1.09e-05	177	38	5	873_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	1.09e-05	177	38	5	3227_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	1.12e-05	178	38	5	4710_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	1.12e-05	178	38	5	7245_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	1.12e-05	178	38	5	1112_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	1.12e-05	178	38	5	992_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2 FERMT1	1.12e-05	178	38	5	6276_DN
Drug	trichostatin A; Down 200; 0.1uM; MCF7; HG-U133A	SREK1 SFSWAP LUC7L2 SON FERMT1	1.16e-05	179	38	5	331_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 LUC7L2 FERMT1	1.16e-05	179	38	5	5484_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	DIDO1 SREK1 SRSF4 SRRM2 LUC7L2	1.22e-05	181	38	5	7077_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	NUSAP1 SMARCC1 SFSWAP SRRM2 SON	1.43e-05	187	38	5	4302_DN
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; HL60; HT_HG-U133A	NUSAP1 SMARCC1 SFSWAP SRRM2 SON	1.75e-05	195	38	5	6159_DN
Drug	Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HG-U133A	SMARCC1 SRRM2 RRP1B ARGLU1 CLK1	1.97e-05	200	38	5	1920_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	1.47e-04	161	38	4	4768_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRRM2 LUC7L2	1.55e-04	163	38	4	7453_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 FERMT1	1.55e-04	163	38	4	5594_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRRM2 LUC7L2 FERMT1	1.58e-04	164	38	4	4388_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRRM2 LUC7L2 FERMT1	1.70e-04	167	38	4	3979_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	1.74e-04	168	38	4	3868_DN
Drug	((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one)	SRSF4 CLK1	1.77e-04	12	38	2	ctd:C578491
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	1.78e-04	169	38	4	5572_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 FERMT1	1.78e-04	169	38	4	5231_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	DIDO1 SRSF4 SRRM2 LUC7L2	1.82e-04	170	38	4	3791_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 FERMT1	1.86e-04	171	38	4	6879_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DDX23 SREK1 SRSF4 LUC7L2	1.86e-04	171	38	4	4954_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRRM2 LUC7L2 FERMT1	1.90e-04	172	38	4	3428_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 FERMT1	1.90e-04	172	38	4	2330_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 FERMT1	1.90e-04	172	38	4	5209_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 FERMT1	1.90e-04	172	38	4	1637_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 FERMT1	1.90e-04	172	38	4	6993_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 LUC7L2	1.90e-04	172	38	4	4112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	1.94e-04	173	38	4	5336_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	DIDO1 SRSF4 SRRM2 LUC7L2	1.99e-04	174	38	4	3993_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 FERMT1	1.99e-04	174	38	4	3462_DN
Drug	HC toxin from Helminthosporium carbonum; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	SREK1 SRSF4 SRRM2 LUC7L2	1.99e-04	174	38	4	909_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 LUC7L2	1.99e-04	174	38	4	5945_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 LUC7L2 BRWD1	1.99e-04	174	38	4	5693_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRRM2 LUC7L2	1.99e-04	174	38	4	6493_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	DIDO1 SREK1 SRSF4 LUC7L2	2.03e-04	175	38	4	1058_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	2.03e-04	175	38	4	7387_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SREK1 SRSF4 SRRM2 LUC7L2	2.03e-04	175	38	4	1014_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRRM2 LUC7L2	2.07e-04	176	38	4	2639_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 SON	2.07e-04	176	38	4	6932_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	2.07e-04	176	38	4	3312_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	SREK1 CLK1 LUC7L2 BRWD1	2.07e-04	176	38	4	6980_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	2.07e-04	176	38	4	6784_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SREK1 FAM193A SRSF4 LUC7L2	2.07e-04	176	38	4	981_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 FERMT1	2.12e-04	177	38	4	1645_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SMARCC1 SREK1 SRSF4 LUC7L2	2.12e-04	177	38	4	6972_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DDX23 SREK1 SRSF4 LUC7L2	2.12e-04	177	38	4	5308_DN
Drug	Etifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A	SMARCC1 SRRM2 PRPF40A SON	2.17e-04	178	38	4	3998_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	2.17e-04	178	38	4	1471_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SRSF4 SRRM2 LUC7L2 BRWD1	2.17e-04	178	38	4	5086_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	DIDO1 SRSF4 SRRM2 LUC7L2	2.21e-04	179	38	4	6609_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRRM2 LUC7L2 FERMT1	2.26e-04	180	38	4	6454_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	SRSF4 SFSWAP SRRM2 LUC7L2	2.26e-04	180	38	4	5981_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRRM2 CLK1 LUC7L2	2.26e-04	180	38	4	5511_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	2.26e-04	180	38	4	4821_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SREK1 SRSF4 SRRM2 LUC7L2	2.31e-04	181	38	4	3643_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DIDO1 SREK1 SRSF4 LUC7L2	2.31e-04	181	38	4	6951_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	FAM193A SRSF4 SRRM2 LUC7L2	2.36e-04	182	38	4	5802_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	DIDO1 SRSF4 SRRM2 LUC7L2	2.46e-04	184	38	4	7555_DN
Drug	geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A	DIDO1 PDE12 SZT2 CLK1	2.56e-04	186	38	4	1228_UP
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	SMARCC1 SFSWAP PRPF40A SON	2.67e-04	188	38	4	6735_DN
Drug	2-propylpentanoic acid; Down 200; 10000uM; HL60; HG-U133A	DIDO1 SREK1 SRRM2 LUC7L2	2.72e-04	189	38	4	410_DN
Drug	resveratrol; Down 200; 50uM; MCF7; HG-U133A	NUSAP1 FAM193A SRRM2 ARGLU1	2.78e-04	190	38	4	622_DN
Drug	GSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A	DIDO1 RRP1B SZT2 SON	2.78e-04	190	38	4	7070_UP
Drug	Salbutamol [18559-94-9]; Down 200; 16.8uM; PC3; HT_HG-U133A	DIDO1 RRP1B BCORL1 BRWD1	2.83e-04	191	38	4	7376_DN
Drug	17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	PDE12 RRP1B SZT2 SPINK5	2.83e-04	191	38	4	993_UP
Drug	Ivermectin [70288-86-7]; Down 200; 4.6uM; PC3; HT_HG-U133A	SFSWAP RRP1B LUC7L2 BRWD1	3.13e-04	196	38	4	2051_DN
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	SFSWAP RRP1B BCORL1 FERMT1	3.13e-04	196	38	4	1695_DN
Drug	R(+)-verapamil hydrochloride; Down 200; 10uM; MCF7; HG-U133A	SMARCC1 SRSF4 ARGLU1 SON	3.19e-04	197	38	4	164_DN
Drug	Morantel tartrate [26155-31-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	SMARCC1 SRRM2 RRP1B BRWD1	3.19e-04	197	38	4	1798_DN
Drug	Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A	DIDO1 SRRM2 RRP1B BRWD1	3.19e-04	197	38	4	2070_DN
Drug	(R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A	CLK1 BCORL1 FERMT1 SPINK5	3.38e-04	200	38	4	4841_DN
Disease	hip bone mineral density, hip bone size	DDX56 FAM193A	2.26e-03	56	37	2	EFO_0004844, EFO_0007702
Disease	hypertension, white matter hyperintensity measurement	PLEKHG1 ZNF106	2.76e-03	62	37	2	EFO_0000537, EFO_0005665
Disease	hip bone size	DDX56 FAM193A	3.03e-03	65	37	2	EFO_0004844

Protein segments in the cluster

Peptide	Gene	Start	Entry
EPRACKAQSKAHKRR	C1orf167	1291	Q5SNV9
RVKLFPHRNSSKCKS	CFTR	1446	P13569
KSSKHNKKRSRSRSR	ARGLU1	16	Q9NWB6
PRCAKRHKSKQLAAR	FERMT1	521	Q9BQL6
AKAVVRSSHRPKCRK	BCORL1	1136	Q5H9F3
KPVSSTRAAKRARHK	FAM193A	861	P78312
KWRSSSSHKRRKRSH	CLK1	21	P49759
SQKRARHLARAPKAT	SPINK5	76	Q9NQ38
PASKSHKRERNLSAK	KATNIP	266	O60303
AKRAKSQNPLRSFKH	DDX56	521	Q9NY93
ASASSSAKKREHPRK	C9orf131	936	Q5VYM1
HAKAAAAKKSRKSRP	PDE12	86	Q6L8Q7
SASSPRRAVHKKNNK	MYRFL	596	Q96LU7
NEHKRSLTKTPARKS	NUSAP1	291	Q9BXS6
RKSSPSKDRKRHRSR	DDX23	36	Q9BUQ8
KERAHQKRSSKRAPQ	SLC9A3R1	331	O14745
DRTRQRSESKHKSPK	PRPF40A	906	O75400
SRTKLHNESKKTAPR	DIDO1	781	Q9BTC0
RKSSRKLPHRNASAA	BRWD1	2261	Q9NSI6
TPKKRRKSRTAFTNH	LBX1	121	P52954
EKLRRSRSHSKNPKR	LUC7L2	256	Q9Y383
RREKKDRHPSRKSSH	GARIN3	431	Q8TC56
SASSNPALALRRKKH	SZT2	376	Q5T011
KSRSPSKEKSRSRSH	SRSF4	246	Q08170
PSRHKSKSKSRSRSQ	SRSF4	291	Q08170
SPHEKKKKRRSRSRT	SFSWAP	846	Q12872
TSRKNTPHFNRKRLS	RRP1B	311	Q14684
RAKRDKSHSHTPSRR	SRRM2	466	Q9UQ35
RSSRHRGKVKSFPKD	RPL3	21	P39023
RSRQKDRRRSKSPHK	SREK1	226	Q8WXA9
DRRRSKSPHKKRSKS	SREK1	231	Q8WXA9
RKASANARKRKHSPS	SMARCC1	316	Q92922
TRRHPNTQQRASKKK	NCAPD2	1346	Q15021
NKARDHSRSRSPNKA	SRRM5	456	B3KS81
RSFSKKRRHSSSSPK	SRRM4	146	A7MD48
KRRHSSSSPKSKRRD	SRRM4	151	A7MD48
SSSPKSKRRDEKRHK	SRRM4	156	A7MD48
LEASHRSRPKKNNSR	PITPNM3	886	Q9BZ71
KKSNRRSRSKSRSSH	ZRANB2	196	O95218
KKLHRSSANPSFKRL	ZSWIM3	316	Q96MP5
RRKSEPSSRSHKVLK	PLEKHG1	466	Q9ULL1
RKKKSLRAAHVPENS	ZNF106	1356	Q9H2Y7
RARKRSSKSKSHRSQ	SON	1846	P18583
KSHSSKRIRPRACKN	MYPN	166	Q86TC9