Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSBG2 ACSS2 ACSM2A ACSM2B	1.95e-06	26	70	4	GO:0015645
GeneOntologyMolecularFunction	CoA-ligase activity	ACSBG2 ACSS2 ACSM2A ACSM2B	2.29e-06	27	70	4	GO:0016405
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSBG2 ACSS2 ACSM2A ACSM2B	4.06e-06	31	70	4	GO:0016878
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSBG2 ACSS2 ACSM2A ACSM2B	1.27e-05	41	70	4	GO:0016877
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	RGPD8 PPIL3 RGPD1 PPIL2	2.82e-05	50	70	4	GO:0003755
GeneOntologyMolecularFunction	cis-trans isomerase activity	RGPD8 PPIL3 RGPD1 PPIL2	3.56e-05	53	70	4	GO:0016859
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	3.63e-05	3	70	2	GO:0018858
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RGPD8 HPS4 SBF2 RGPD1 ALS2 HERC2 HERC1 RGS12 RGPD5	6.71e-05	507	70	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RGPD8 HPS4 SBF2 RGPD1 ALS2 HERC2 HERC1 RGS12 RGPD5	6.71e-05	507	70	9	GO:0030695
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	7.24e-05	4	70	2	GO:0102391
GeneOntologyMolecularFunction	acyltransferase activity	RGPD8 BRCA2 RGPD1 TRIM71 IRF2BPL PPIL2 HERC2 HERC1 ACSM2A ACSM2B NEDD4	7.50e-05	775	70	11	GO:0016746
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM2A ACSM2B	3.35e-04	8	70	2	GO:0004321
GeneOntologyMolecularFunction	ligase activity	ACSBG2 ACSS2 ACSM2A GSS ACSM2B	3.63e-04	174	70	5	GO:0016874
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RGPD8 RGPD1 TRIM71 IRF2BPL PPIL2 HERC2 HERC1 NEDD4	4.14e-04	512	70	8	GO:0019787
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RGPD8 RGPD1 TRIM71 IRF2BPL PPIL2 HERC2 NEDD4	4.83e-04	398	70	7	GO:0061659
GeneOntologyMolecularFunction	aminoacyltransferase activity	RGPD8 RGPD1 TRIM71 IRF2BPL PPIL2 HERC2 HERC1 NEDD4	5.33e-04	532	70	8	GO:0016755
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM2A ACSM2B	6.53e-04	11	70	2	GO:0031956
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	HPS4 SBF2 ALS2 HERC2 HERC1	1.30e-03	231	70	5	GO:0005085
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1B WDR5	2.21e-03	20	70	2	GO:0042800
GeneOntologyMolecularFunction	SUMO ligase activity	RGPD8 RGPD1	2.21e-03	20	70	2	GO:0061665
GeneOntologyMolecularFunction	C-acyltransferase activity	ACSM2A ACSM2B	2.44e-03	21	70	2	GO:0016408
GeneOntologyMolecularFunction	GTPase activator activity	RGPD8 RGPD1 ALS2 RGS12 RGPD5	2.97e-03	279	70	5	GO:0005096
GeneOntologyMolecularFunction	methylated histone binding	L3MBTL2 WDR5 PHF8	3.43e-03	86	70	3	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	L3MBTL2 WDR5 PHF8	3.66e-03	88	70	3	GO:0140034
GeneOntologyMolecularFunction	fatty acyl-CoA hydrolase activity	ACSBG2 ABCD1	4.02e-03	27	70	2	GO:0047617
GeneOntologyMolecularFunction	acyl-CoA hydrolase activity	ACSBG2 ABCD1	4.32e-03	28	70	2	GO:0016289
GeneOntologyBiologicalProcess	small molecule biosynthetic process	RGPD8 ASAH1 RGPD1 OSBPL6 RTN4IP1 ACSBG2 APOB WDR5 ABCD1 H6PD ACSS2 ACSM2A ACSM2B	3.82e-07	676	70	13	GO:0044283
GeneOntologyBiologicalProcess	protein peptidyl-prolyl isomerization	RGPD8 PPIL3 RGPD1 PPIL2	8.23e-06	38	70	4	GO:0000413
GeneOntologyBiologicalProcess	peptidyl-proline modification	RGPD8 PPIL3 RGPD1 PPIL2	3.38e-05	54	70	4	GO:0018208
GeneOntologyBiologicalProcess	acyl-CoA metabolic process	ACSBG2 ABCD1 ACSS2 ACSM2A ACSM2B	3.46e-05	109	70	5	GO:0006637
GeneOntologyBiologicalProcess	thioester metabolic process	ACSBG2 ABCD1 ACSS2 ACSM2A ACSM2B	3.46e-05	109	70	5	GO:0035383
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	RGPD8 RGPD1 RGPD5	4.09e-05	20	70	3	GO:0006607
GeneOntologyBiologicalProcess	lipid biosynthetic process	ASAH1 AVIL CAPN2 OSBPL6 ACSBG2 APOB ABCD1 H6PD ACSS2 ACSM2A ACSM2B	8.62e-05	813	70	11	GO:0008610
GeneOntologyBiologicalProcess	nucleoside bisphosphate metabolic process	ACSBG2 ABCD1 ACSS2 ACSM2A ACSM2B	1.22e-04	142	70	5	GO:0033865
GeneOntologyBiologicalProcess	ribonucleoside bisphosphate metabolic process	ACSBG2 ABCD1 ACSS2 ACSM2A ACSM2B	1.22e-04	142	70	5	GO:0033875
GeneOntologyBiologicalProcess	purine nucleoside bisphosphate metabolic process	ACSBG2 ABCD1 ACSS2 ACSM2A ACSM2B	1.22e-04	142	70	5	GO:0034032
GeneOntologyBiologicalProcess	fatty acid derivative metabolic process	ACSBG2 CYP4F3 ABCD1 ACSM2A	1.74e-04	82	70	4	GO:1901568
GeneOntologyBiologicalProcess	regulation of lipid biosynthetic process	ASAH1 AVIL CAPN2 APOB ABCD1 H6PD	1.88e-04	246	70	6	GO:0046890
GeneOntologyBiologicalProcess	sulfur compound metabolic process	CSGALNACT2 ACSBG2 ABCD1 ACSS2 ACSM2A GSS ACSM2B	2.36e-04	365	70	7	GO:0006790
GeneOntologyBiologicalProcess	monocarboxylic acid biosynthetic process	OSBPL6 ACSBG2 ABCD1 ACSS2 ACSM2A ACSM2B	2.53e-04	260	70	6	GO:0072330
GeneOntologyBiologicalProcess	fatty-acyl-CoA metabolic process	ACSBG2 ABCD1 ACSM2A	3.91e-04	42	70	3	GO:0035337
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD8 RGPD1	4.02e-04	9	70	2	GO:0033133
GeneOntologyBiologicalProcess	fatty acid biosynthetic process	ACSBG2 ABCD1 ACSS2 ACSM2A ACSM2B	4.80e-04	191	70	5	GO:0006633
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD8 RGPD1	5.02e-04	10	70	2	GO:1903301
GeneOntologyCellularComponent	perinuclear region of cytoplasm	FAT1 AATK CHERP RGPD8 LNPEP SBF2 CAPN2 RGPD1 OSBPL6 ABCD1 NEDD4	2.93e-04	934	71	11	GO:0048471
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD8 RGPD1	3.14e-04	8	71	2	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD8 RGPD1	5.03e-04	10	71	2	GO:0044614
Domain	AMP-binding_CS	ACSBG2 ACSS2 ACSM2A ACSM2B	2.69e-06	26	71	4	IPR020845
Domain	AMP_BINDING	ACSBG2 ACSS2 ACSM2A ACSM2B	3.66e-06	28	71	4	PS00455
Domain	AMP-binding	ACSBG2 ACSS2 ACSM2A ACSM2B	4.88e-06	30	71	4	PF00501
Domain	AMP-dep_Synth/Lig	ACSBG2 ACSS2 ACSM2A ACSM2B	4.88e-06	30	71	4	IPR000873
Domain	Grip	RGPD8 RGPD1 RGPD5	8.50e-06	11	71	3	SM00755
Domain	GRIP	RGPD8 RGPD1 RGPD5	8.50e-06	11	71	3	PF01465
Domain	Ran_BP1	RGPD8 RGPD1 RGPD5	1.13e-05	12	71	3	PF00638
Domain	GRIP_dom	RGPD8 RGPD1 RGPD5	1.13e-05	12	71	3	IPR000237
Domain	GRIP	RGPD8 RGPD1 RGPD5	1.13e-05	12	71	3	PS50913
Domain	RANBD1	RGPD8 RGPD1 RGPD5	1.13e-05	12	71	3	PS50196
Domain	NHL	TENM4 TRIM71 TENM2	1.47e-05	13	71	3	PS51125
Domain	RanBD	RGPD8 RGPD1 RGPD5	1.47e-05	13	71	3	SM00160
Domain	Ran_bind_dom	RGPD8 RGPD1 RGPD5	1.47e-05	13	71	3	IPR000156
Domain	AMP-bd_C	ACSS2 ACSM2A ACSM2B	3.45e-05	17	71	3	IPR025110
Domain	AMP-binding_C	ACSS2 ACSM2A ACSM2B	3.45e-05	17	71	3	PF13193
Domain	Rhs_assc_core	TENM4 TENM2	4.26e-05	3	71	2	IPR022385
Domain	RCC1	ALS2 HERC2 HERC1	5.73e-05	20	71	3	PF00415
Domain	RCC1_1	ALS2 HERC2 HERC1	6.67e-05	21	71	3	PS00625
Domain	RCC1_2	ALS2 HERC2 HERC1	6.67e-05	21	71	3	PS00626
Domain	RCC1_3	ALS2 HERC2 HERC1	6.67e-05	21	71	3	PS50012
Domain	Reg_chr_condens	ALS2 HERC2 HERC1	7.70e-05	22	71	3	IPR000408
Domain	-	ALS2 HERC2 HERC1	7.70e-05	22	71	3	2.130.10.30
Domain	Tox-GHH_dom	TENM4 TENM2	8.51e-05	4	71	2	IPR028916
Domain	Ten_N	TENM4 TENM2	8.51e-05	4	71	2	IPR009471
Domain	Ten_N	TENM4 TENM2	8.51e-05	4	71	2	PF06484
Domain	TENEURIN_N	TENM4 TENM2	8.51e-05	4	71	2	PS51361
Domain	Tox-GHH	TENM4 TENM2	8.51e-05	4	71	2	PF15636
Domain	RCC1/BLIP-II	ALS2 HERC2 HERC1	8.83e-05	23	71	3	IPR009091
Domain	YD	TENM4 TENM2	1.41e-04	5	71	2	IPR006530
Domain	HECT	HERC2 HERC1 NEDD4	1.44e-04	27	71	3	PF00632
Domain	HECTc	HERC2 HERC1 NEDD4	1.44e-04	27	71	3	SM00119
Domain	HECT_dom	HERC2 HERC1 NEDD4	1.44e-04	27	71	3	IPR000569
Domain	HECT	HERC2 HERC1 NEDD4	1.44e-04	27	71	3	PS50237
Domain	GCC2_Rab_bind	RGPD8 RGPD1	2.96e-04	7	71	2	IPR032023
Domain	Rab_bind	RGPD8 RGPD1	2.96e-04	7	71	2	PF16704
Domain	TPR_1	RGPD8 RGPD1 IFIT5 RGPD5	3.83e-04	90	71	4	PF00515
Domain	TPR_1	RGPD8 RGPD1 IFIT5 RGPD5	3.83e-04	90	71	4	IPR001440
Domain	Villin/Gelsolin	AVIL SCIN	3.93e-04	8	71	2	IPR007122
Domain	GEL	AVIL SCIN	3.93e-04	8	71	2	SM00262
Domain	-	TENM4 TRIM71 TENM2	4.36e-04	39	71	3	2.120.10.30
Domain	-	RGPD8 RGPD1	6.29e-04	10	71	2	1.10.220.60
Domain	6-blade_b-propeller_TolB-like	TENM4 TRIM71 TENM2	7.11e-04	46	71	3	IPR011042
Domain	PH_dom-like	RGPD8 SBF2 RGPD1 OSBPL6 ALS2 RGS12 RGPD5	1.16e-03	426	71	7	IPR011993
Domain	Gelsolin	AVIL SCIN	1.26e-03	14	71	2	PF00626
Domain	MORN	ALS2 MORN3	1.26e-03	14	71	2	SM00698
Domain	Gelsolin-like_dom	AVIL SCIN	1.26e-03	14	71	2	IPR007123
Domain	MORN	ALS2 MORN3	1.45e-03	15	71	2	IPR003409
Domain	MORN	ALS2 MORN3	1.45e-03	15	71	2	PF02493
Domain	CarboxyPept-like_regulatory	TENM4 TENM2	1.87e-03	17	71	2	IPR008969
Domain	Cyclophilin-type_PPIase_CS	PPIL3 PPIL2	2.34e-03	19	71	2	IPR020892
Domain	TPR-contain_dom	RGPD8 RGPD1 IFIT5 RGPD5	2.56e-03	150	71	4	IPR013026
Domain	Cyclophilin-type_PPIase	PPIL3 PPIL2	2.86e-03	21	71	2	IPR024936
Domain	Cyclophilin-like_dom	PPIL3 PPIL2	3.13e-03	22	71	2	IPR029000
Domain	CSA_PPIASE_2	PPIL3 PPIL2	3.13e-03	22	71	2	PS50072
Domain	Pro_isomerase	PPIL3 PPIL2	3.13e-03	22	71	2	PF00160
Domain	-	PPIL3 PPIL2	3.13e-03	22	71	2	2.40.100.10
Domain	Cyclophilin-type_PPIase_dom	PPIL3 PPIL2	3.13e-03	22	71	2	IPR002130
Domain	CSA_PPIASE_1	PPIL3 PPIL2	3.13e-03	22	71	2	PS00170
Domain	G_patch	CHERP GPATCH3	3.42e-03	23	71	2	SM00443
Domain	G_patch_dom	CHERP GPATCH3	3.42e-03	23	71	2	IPR000467
Domain	G_PATCH	CHERP GPATCH3	3.42e-03	23	71	2	PS50174
Domain	G-patch	CHERP GPATCH3	3.42e-03	23	71	2	PF01585
Domain	WD40_repeat_CS	CDC40 WDR5 HERC1 WDR59	3.53e-03	164	71	4	IPR019775
Domain	TPR_REGION	RGPD8 RGPD1 IFIT5 RGPD5	3.60e-03	165	71	4	PS50293
Domain	TPR	RGPD8 RGPD1 IFIT5 RGPD5	3.60e-03	165	71	4	PS50005
Domain	-	RGPD8 SBF2 RGPD1 OSBPL6 ALS2 RGS12	3.69e-03	391	71	6	2.30.29.30
Domain	ADF-H/Gelsolin-like_dom	AVIL SCIN	3.73e-03	24	71	2	IPR029006
Domain	-	AVIL SCIN	3.73e-03	24	71	2	3.40.20.10
Domain	WD40_repeat	CDC40 WDR5 HERC2 HERC1 WDR59	3.76e-03	272	71	5	IPR001680
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD8 RGPD1 RGPD5	2.84e-07	7	71	3	15710750
Pubmed	CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.	CDC40 HERC2 PHF8 FER1L5 KCNH5	1.46e-06	94	71	5	37468549
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	4.11e-06	2	71	2	16521160
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	4.11e-06	2	71	2	19634011
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	4.11e-06	2	71	2	29948332
Pubmed	Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling.	NTRK1 NEDD4	4.11e-06	2	71	2	21332718
Pubmed	Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.	SLC12A3 NEDD4	1.23e-05	3	71	2	21852580
Pubmed	TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum.	MIA2 APOB	1.23e-05	3	71	2	27138255
Pubmed	Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders.	L3MBTL2 WSCD2	1.23e-05	3	71	2	27918536
Pubmed	BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.	BRCA2 NTRK1	1.23e-05	3	71	2	28591715
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1B TENM4 ALS2 CEP192 PHF8 TENM2 NEDD4	1.99e-05	407	71	7	12693553
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	HERC2 HERC1 NEDD4	2.05e-05	26	71	3	26949039
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	TENM4 ASAH1 LNPEP ABCD1 H6PD	2.22e-05	164	71	5	32409323
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM4 TENM2	2.46e-05	4	71	2	10225957
Pubmed	Identification of novel stress-induced genes downstream of chop.	TENM4 AVIL	2.46e-05	4	71	2	9649432
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RGPD8 RGPD5	2.46e-05	4	71	2	9480752
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM4 TENM2	2.46e-05	4	71	2	12000766
Pubmed	Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.	ACSM2A ACSM2B	2.46e-05	4	71	2	32830538
Pubmed	Human transcription factor protein interaction networks.	FAT1 L3MBTL2 PPIL3 RGPD1 IRF2BPL PPIL2 WDR5 CEP192 HERC2 HERC1 PHF8 MRPL49	3.00e-05	1429	71	12	35140242
Pubmed	Functions of gelsolin: motility, signaling, apoptosis, cancer.	AVIL SCIN	4.09e-05	5	71	2	10047530
Pubmed	Model-based prediction of human hair color using DNA variants.	EXOC2 HERC2	4.09e-05	5	71	2	21197618
Pubmed	Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma.	CHERP WDR5 MRPL49	5.09e-05	35	71	3	30942445
Pubmed	Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).	NTRK1 NEDD4	6.13e-05	6	71	2	27445338
Pubmed	Genetic differences between five European populations.	EXOC2 HERC2	6.13e-05	6	71	2	20616560
Pubmed	Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination.	NTRK1 NEDD4	6.13e-05	6	71	2	16701206
Pubmed	PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation.	WDR5 PHF8	6.13e-05	6	71	2	20208542
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FAT1 AATK LMAN2L SETD1B SBF2 CEP192 ABCD1 HERC2 HERC1 WDR59	8.01e-05	1105	71	10	35748872
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD8 RGPD1	8.57e-05	7	71	2	21205196
Pubmed	CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.	SETD1B WDR5	8.57e-05	7	71	2	19433449
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD8 RGPD1	8.57e-05	7	71	2	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD8 RGPD1	8.57e-05	7	71	2	25187515
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD8 RGPD1	8.57e-05	7	71	2	9037092
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD8 RGPD1	8.57e-05	7	71	2	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD8 RGPD1	8.57e-05	7	71	2	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD8 RGPD1	8.57e-05	7	71	2	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD8 RGPD1	8.57e-05	7	71	2	23818861
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD8 RGPD1	8.57e-05	7	71	2	11353387
Pubmed	The ancestral gene for transcribed, low-copy repeats in the Prader-Willi/Angelman region encodes a large protein implicated in protein trafficking, which is deficient in mice with neuromuscular and spermiogenic abnormalities.	HERC2 HERC1	8.57e-05	7	71	2	9949213
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD8 RGPD1	8.57e-05	7	71	2	30944974
Pubmed	The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.	TENM4 TENM2	8.57e-05	7	71	2	10625539
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD8 RGPD1	8.57e-05	7	71	2	38838144
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD8 RGPD1	8.57e-05	7	71	2	23536549
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD8 RGPD1	8.57e-05	7	71	2	7559465
Pubmed	The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.	TENM4 TENM2	8.57e-05	7	71	2	12915301
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD8 RGPD1	8.57e-05	7	71	2	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD8 RGPD1	8.57e-05	7	71	2	38657106
Pubmed	Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.	HERC2 RGS12	8.57e-05	7	71	2	36700049
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD8 RGPD1	8.57e-05	7	71	2	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD8 RGPD1	8.57e-05	7	71	2	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD8 RGPD1	8.57e-05	7	71	2	20682751
Pubmed	CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.	SETD1B WDR5	1.14e-04	8	71	2	18680430
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD8 RGPD1	1.14e-04	8	71	2	22262462
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD8 RGPD1	1.14e-04	8	71	2	21670213
Pubmed	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	EXOC2 HERC2	1.14e-04	8	71	2	18483556
Pubmed	Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.	TENM4 TENM2	1.14e-04	8	71	2	10331952
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD8 RGPD1	1.14e-04	8	71	2	28745977
Pubmed	Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia.	SLC12A3 APOB	1.14e-04	8	71	2	18496130
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	SETD1B WDR5	1.14e-04	8	71	2	22266653
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD8 RGPD1	1.14e-04	8	71	2	27412403
Pubmed	Genomic response to Wnt signalling is highly context-dependent--evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets.	ALS2 TENM2	1.14e-04	8	71	2	19563800
Pubmed	Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.	SETD1B WDR5	1.14e-04	8	71	2	17355966
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD8 RGPD1	1.14e-04	8	71	2	21310149
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CHERP RGPD8 CDC40 L3MBTL2 ASAH1 RGPD1 WDR5 CEP192 HERC2 RGPD5	1.15e-04	1155	71	10	20360068
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	SETD1B CAPN2 PPIL2 WDR5 ACSM2A PTK6 KCNH5 NEDD4	1.20e-04	730	71	8	34857952
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	SETD1B WDR5	1.47e-04	9	71	2	22665483
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD8 RGPD1	1.47e-04	9	71	2	18394993
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD8 RGPD1	1.47e-04	9	71	2	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD8 RGPD1	1.47e-04	9	71	2	10601307
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD8 RGPD1	1.47e-04	9	71	2	9733766
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD8 RGPD1	1.47e-04	9	71	2	28100513
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD8 RGPD1	1.47e-04	9	71	2	28877029
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD8 RGPD1	1.47e-04	9	71	2	17887960
Pubmed	Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.	SETD1B WDR5	1.83e-04	10	71	2	17998332
Pubmed	U box proteins as a new family of ubiquitin-protein ligases.	PPIL2 NEDD4	1.83e-04	10	71	2	11435423
Pubmed	Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS.	SETD1B WDR5	1.83e-04	10	71	2	18838538
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD8 RGPD1	1.83e-04	10	71	2	8857542
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD8 RGPD1	1.83e-04	10	71	2	27160050
Pubmed	Genetic determinants of hair, eye and skin pigmentation in Europeans.	EXOC2 HERC2	1.83e-04	10	71	2	17952075
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD8 RGPD1	1.83e-04	10	71	2	16332688
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM4 TENM2	1.83e-04	10	71	2	38713721
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD8 RGPD1	1.83e-04	10	71	2	21859863
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	ASAH1 HERC2 HERC1 WDR59	1.93e-04	139	71	4	25476789
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	SETD1B RGPD8 BRCA2 PPIL2 CEP192 SCIN PTK6	1.99e-04	588	71	7	38580884
Pubmed	ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.	BRCA2 NTRK1 APOB	2.20e-04	57	71	3	23788249
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD8 RGPD1	2.23e-04	11	71	2	35771867
Pubmed	Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1.	BRCA2 NEDD4	2.23e-04	11	71	2	15001356
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD8 RGPD1	2.23e-04	11	71	2	17069463
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD8 RGPD1	2.23e-04	11	71	2	34110283
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RGPD8 BRCA2 L3MBTL2 RGPD1	2.33e-04	146	71	4	23892456
Pubmed	RhoA is dispensable for axon guidance of sensory neurons in the mouse dorsal root ganglia.	NTRK1 AVIL	2.68e-04	12	71	2	22661927
Pubmed	Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo.	NTRK1 AVIL	2.68e-04	12	71	2	32690615
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	SETD1B WDR5	2.68e-04	12	71	2	27563068
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD8 RGPD1	3.16e-04	13	71	2	31427429
Pubmed	Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.	CHERP SBF2 CAPN2 OSBPL6	3.88e-04	167	71	4	25659891
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1B CDC40 L3MBTL2 CAPN2 WDR5 EXOC2 HERC2 PHF8 MRPL49 WDR59	4.10e-04	1353	71	10	29467282
Pubmed	A genome-wide association study on obesity and obesity-related traits.	FAT1 ASAH1	4.24e-04	15	71	2	21552555
Pubmed	Molecular identification of rapidly adapting mechanoreceptors and their developmental dependence on ret signaling.	NTRK1 AVIL	4.24e-04	15	71	2	20064391
Pubmed	Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.	EXOC2 HERC2	4.24e-04	15	71	2	23548203
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RGPD8 RGPD1	4.24e-04	15	71	2	14697343
Pubmed	SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.	SETD1B WDR5	4.84e-04	16	71	2	23870121
Interaction	UCHL5 interactions	RGPD8 BRCA2 POTEF NTRK1 PSMB8 APOB HERC2 RGPD5	1.45e-05	319	70	8	int:UCHL5
Interaction	RGPD3 interactions	MIA2 RGPD8 RGPD1 RGPD5	2.13e-05	47	70	4	int:RGPD3
Interaction	NPIPB6 interactions	RGPD8 RGPD1 RGPD5	3.15e-05	18	70	3	int:NPIPB6
Interaction	PMS1 interactions	BRCA2 NTRK1 SBF2 CAPN2 HERC2	3.23e-05	105	70	5	int:PMS1
Interaction	WDR59 interactions	NTRK1 AVIL WDR5 HERC2 WDR59	3.86e-05	109	70	5	int:WDR59
Interaction	ABCB1 interactions	NTRK1 PSMB8 IFIT5 NEDD4	4.59e-05	57	70	4	int:ABCB1
Interaction	HSD17B7P2 interactions	BRCA2 POTEF WDR59	5.10e-05	21	70	3	int:HSD17B7P2
Interaction	RGPD4 interactions	RGPD8 RGPD1 RGPD5	5.89e-05	22	70	3	int:RGPD4
Interaction	ACSM2A interactions	ACSM2A ACSM2B	7.10e-05	4	70	2	int:ACSM2A
Interaction	ACSM2B interactions	ACSM2A ACSM2B	7.10e-05	4	70	2	int:ACSM2B
Interaction	TBK1 interactions	POLR3E NTRK1 IRF2BPL APOB CEP192 EXOC2 HERC2 NEDD4	7.50e-05	402	70	8	int:TBK1
Interaction	KANSL2 interactions	SETD1B L3MBTL2 PPIL2 WDR5	1.03e-04	70	70	4	int:KANSL2
Interaction	RGPD2 interactions	RGPD8 RGPD1 RGPD5	1.11e-04	27	70	3	int:RGPD2
GeneFamily	Acyl-CoA synthetase family	ACSBG2 ACSS2 ACSM2A ACSM2B	1.26e-06	26	57	4	40
GeneFamily	Gelsolin/villins	AVIL SCIN	2.70e-04	8	57	2	950
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD8 RGPD1 IFIT5 RGPD5	4.73e-04	115	57	4	769
GeneFamily	Cyclophilin peptidylprolyl isomerases	PPIL3 PPIL2	1.61e-03	19	57	2	909
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	CHERP GPATCH3	2.17e-03	22	57	2	579
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 OSBPL6 TRIM71 CYP4F3 ACSM2A ACSM2B	4.35e-07	180	71	6	1363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 OSBPL6 CYP4F3 ACSS2 ACSM2A ACSM2B	5.28e-07	186	71	6	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	SLC16A9 OSBPL6 CYP4F3 ACSS2 ACSM2A ACSM2B	5.44e-07	187	71	6	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	pdx-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SLC38A4 CYP4F3 ACSM2A NAALADL2 PTK6 ACSM2B	5.97e-07	190	71	6	b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	MIA2 SLC12A3 CYP4F3 ACSM2A ACSM2B	4.78e-06	154	71	5	89a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	MIA2 SLC12A3 CYP4F3 ACSM2A ACSM2B	4.78e-06	154	71	5	f1fea1a87e977221fa125b62287368be9af4987d
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	MIA2 SLC12A3 CYP4F3 ACSM2A ACSM2B	4.78e-06	154	71	5	b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	MIA2 SLC12A3 CYP4F3 ACSM2A ACSM2B	4.78e-06	154	71	5	160b170a3ade8b246843c9854af332475c047ba0
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	NTRK1 WSCD2 ALS2 SCIN NAALADL2	7.30e-06	168	71	5	45ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 TRIM71 CYP4F3 ACSM2A ACSM2B	7.30e-06	168	71	5	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 TRIM71 CYP4F3 ACSM2A ACSM2B	7.95e-06	171	71	5	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 OSBPL6 CYP4F3 ACSM2A ACSM2B	8.41e-06	173	71	5	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT1 SLC16A9 CYP4F3 ACSM2A ACSM2B	1.02e-05	180	71	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT1 SLC16A9 CYP4F3 ACSM2A ACSM2B	1.02e-05	180	71	5	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	367C-Myeloid-Mast_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	ASAH1 NTRK1 OSBPL6 WSCD2 SCIN	1.05e-05	181	71	5	063fc83870f55f63c013f0276c1ec8f3abcbcf27
ToppCell	367C-Myeloid-Mast_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ASAH1 NTRK1 OSBPL6 WSCD2 SCIN	1.05e-05	181	71	5	e1161c9828ee94518eb5bef0b6228d71299c2f59
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MIA2 SLC16A9 CYP4F3 ACSM2A ACSM2B	1.10e-05	183	71	5	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	MIA2 SLC16A9 CYP4F3 ACSM2A ACSM2B	1.13e-05	184	71	5	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 SLC16A9 ACSS2 ACSM2A ACSM2B	1.13e-05	184	71	5	9434731f651820b05335085582960f08fbf895de
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSGALNACT2 AVIL ACSS2 SCIN NEDD4	1.16e-05	185	71	5	5527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 TRIM71 CYP4F3 ACSM2A ACSM2B	1.19e-05	186	71	5	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 TRIM71 CYP4F3 ACSM2A ACSM2B	1.23e-05	187	71	5	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	FAT1 MIA2 CYP4F3 ACSM2A ACSM2B	1.23e-05	187	71	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MIA2 SLC16A9 CYP4F3 ACSM2A ACSM2B	1.26e-05	188	71	5	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MIA2 SLC16A9 CYP4F3 ACSM2A ACSM2B	1.26e-05	188	71	5	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 SLC16A9 TRIM71 ACSM2A ACSM2B	1.29e-05	189	71	5	28b502611829e4a24caff2562545c7db97686099
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SLC38A4 CYP4F3 PHF8 ACSM2A ACSM2B	1.39e-05	192	71	5	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 SLC16A9 ACSM2A NAALADL2 ACSM2B	1.43e-05	193	71	5	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 MIA2 SLC16A9 ACSM2A ACSM2B	1.69e-05	200	71	5	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Papillary_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	AATK CACNA1I CDH18 GSS	2.60e-05	107	71	4	c3695771de30bd1d4da29ae97882f6d7dfdb2242
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NTRK1 WDR5 ABCD1 RGPD5	1.02e-04	152	71	4	ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCell	COVID-19-Mast_cells-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	NTRK1 OSBPL6 ALS2 SCIN	1.13e-04	156	71	4	bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCell	COVID-19-Mast_cells\|COVID-19 / group, cell type (main and fine annotations)	NTRK1 OSBPL6 ALS2 SCIN	1.13e-04	156	71	4	159504d43421ee83b9ab484816333ae549c9c2fd
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Nrip3_(CA1_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CDC40 TRIM71 SCIN	1.15e-04	59	71	3	172f1c6fdc8005a6f21d68a4dc0f8631c265d9e5
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NTRK1 WDR5 ABCD1 RGPD5	1.24e-04	160	71	4	19105debef96ea0c267d6a1d332303ec668ae47e
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HPS4 WSCD2 PHF8 SCIN	1.27e-04	161	71	4	9703b7e67d9fadb6129cad166bd01be915042e44
ToppCell	PND03-Immune-Immune_Myeloid-DC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSMB8 SLA HCLS1 PTK6	1.27e-04	161	71	4	f50e91f8363f20bb7c565aaca4d4961d3fe4b5b5
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A9 APOB ACSS2 GSS	1.30e-04	162	71	4	de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCell	Basal_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	WSCD2 APOB CYP4F3 TENM2	1.34e-04	163	71	4	679e25e5548d157d49a73057a3b5617dccda260f
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ASAH1 SCIN SLA HCLS1	1.40e-04	165	71	4	8a278e72a9a779152de78b6bd55567d82941c5aa
ToppCell	ILEUM-non-inflamed-(4)_Mast\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ASAH1 NTRK1 ALS2 CDH18	1.47e-04	167	71	4	de0cb257def6049830af068f8f74829a708b810f
ToppCell	ILEUM-non-inflamed-(4)_Mast_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ASAH1 NTRK1 ALS2 CDH18	1.47e-04	167	71	4	85b39e05eb6e18e06b47e374d808e479ca65173c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A4 APOB H6PD GSS	1.50e-04	168	71	4	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A4 APOB H6PD GSS	1.50e-04	168	71	4	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A4 APOB H6PD GSS	1.53e-04	169	71	4	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A4 APOB H6PD GSS	1.53e-04	169	71	4	7785cab967a33560830c394c918d6ce625103858
ToppCell	COVID-19-lung-MAST\|lung / Disease (COVID-19 only), tissue and cell type	NTRK1 WSCD2 ALS2 SCIN	1.57e-04	170	71	4	e90f18e5462381b38e918442b38b1c8105291908
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th1\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTRK1 PSMB8 SLA HCLS1	1.64e-04	172	71	4	c0c9a3f5b5fb942b049bc159fd9f21b5b706edd2
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	LMAN2L NTRK1 RTN4IP1 MORN3	1.68e-04	173	71	4	e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H6PD PHF8 ACSS2 SCIN	1.75e-04	175	71	4	b4f01e7782cdd107d0817ef601891fd3a382bc35
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H6PD PHF8 ACSS2 SCIN	1.75e-04	175	71	4	ef6f811d8e1839f405c3b41090ddf79be57a099f
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB H6PD GSS NEDD4	1.75e-04	175	71	4	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	droplet-Fat-Bat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	H6PD PHF8 ACSS2 SCIN	1.75e-04	175	71	4	7f7598d46d10bff1cbea42f950bdde1aaa16e9a4
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ELAPOR2 AVIL CACNA1I SVEP1	1.75e-04	175	71	4	16849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	1.79e-04	176	71	4	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC38A4 APOB CYP4F3 ACSM2B	1.79e-04	176	71	4	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	LMAN2L NTRK1 RTN4IP1 MORN3	1.83e-04	177	71	4	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 ACSS2 ACSM2A ACSM2B	1.83e-04	177	71	4	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTRK1 CACNA1I SLA HCLS1	1.87e-04	178	71	4	307b6e21bc69a0310c550f1fafa8600285e99ccd
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC16A9 CYP4F3 ACSM2A ACSM2B	1.87e-04	178	71	4	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	(3)_Chondrocytes-(32)_Chondro-prehyper-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SLC38A4 WSCD2 SCIN TENM2	1.87e-04	178	71	4	c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT1 TENM4 WSCD2 ACSM2A	1.87e-04	178	71	4	544379f5a6145429762258d426b876bb36c112f5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 OSBPL6 ACSM2A ACSM2B	1.91e-04	179	71	4	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 SLC16A9 ACSM2A ACSM2B	1.91e-04	179	71	4	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	1.91e-04	179	71	4	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	1.95e-04	180	71	4	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LMAN2L NTRK1 RTN4IP1 MORN3	1.95e-04	180	71	4	a682a5d55c612709c9ee9fa4289d6f8bef7fe1af
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A3 CYP4F3 ACSM2A CDH18	1.99e-04	181	71	4	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC16A9 CYP4F3 ACSM2A ACSM2B	1.99e-04	181	71	4	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.04e-04	182	71	4	e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.04e-04	182	71	4	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.04e-04	182	71	4	57bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC16A9 SCIN ACSM2A ACSM2B	2.04e-04	182	71	4	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 ACSBG2 ACSM2A ACSM2B	2.08e-04	183	71	4	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT1 SLC16A9 ACSM2A ACSM2B	2.08e-04	183	71	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.08e-04	183	71	4	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.08e-04	183	71	4	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	FAT1 SLC16A9 ACSM2A ACSM2B	2.12e-04	184	71	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.17e-04	185	71	4	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 ACSM2A ACSM2B NEDD4	2.21e-04	186	71	4	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.21e-04	186	71	4	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	10x5'-Lung-Mast\|Lung / Manually curated celltypes from each tissue	FAT1 NTRK1 WSCD2 SCIN	2.26e-04	187	71	4	f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.26e-04	187	71	4	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	10x5'-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	FAT1 NTRK1 WSCD2 SCIN	2.26e-04	187	71	4	da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.26e-04	187	71	4	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 MIA2 ACSM2A ACSM2B	2.26e-04	187	71	4	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.26e-04	187	71	4	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.26e-04	187	71	4	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.26e-04	187	71	4	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	kidney_cells-Hypertensive_with+without-CKD\|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group	ASAH1 LNPEP IRF2BPL SCIN	2.31e-04	188	71	4	90188b60ff893754f7938fe8edab79758827168e
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	CSGALNACT2 SBF2 SLA HCLS1	2.35e-04	189	71	4	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.35e-04	189	71	4	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Mast_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ASAH1 NTRK1 WSCD2 ALS2	2.35e-04	189	71	4	7bc6e152fb4fe5cd6db9407929c15843a5d8f8c4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.35e-04	189	71	4	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	FAT1 MIA2 ACSM2A ACSM2B	2.35e-04	189	71	4	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.50e-04	192	71	4	3e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCell	3'_v3-Lung-Mast\|Lung / Manually curated celltypes from each tissue	FAT1 NTRK1 OSBPL6 SCIN	2.60e-04	194	71	4	5e6eb81ddc9d5e22c1297734689f476d5a05bff6
ToppCell	3'_v3-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	FAT1 NTRK1 OSBPL6 SCIN	2.60e-04	194	71	4	7b7f1714c4a9d9519c4d0e460cb87f2eb82392dd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC16A9 CYP4F3 ACSM2A ACSM2B	2.70e-04	196	71	4	4ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ASAH1 SCIN SLA HCLS1	2.75e-04	197	71	4	50f994e0d4e69019ec92e164edf3e4e951333766
Drug	Estrone [53-16-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A	KRT24 TENM4 IFIT5 ACSBG2 APOB PHF8 SLA	2.54e-06	195	71	7	6448_UP
Disease	indoleacetoylcarnitine measurement	SLC16A9 ACSM2A ACSM2B	2.54e-07	6	70	3	EFO_0800106
Disease	X-21319 measurement	ACSM2A ACSM2B	5.55e-06	2	70	2	EFO_0800807
Disease	X-11478 measurement	ACSM2A ACSM2B	1.66e-05	3	70	2	EFO_0021242
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	5.52e-05	5	70	2	EFO_0800378
Disease	adrenoleukodystrophy (implicated_via_orthology)	ACSBG2 ABCD1	1.16e-04	7	70	2	DOID:10588 (implicated_via_orthology)
Disease	Tourette syndrome	TENM4 L3MBTL2 TENM2	2.31e-04	50	70	3	EFO_0004895
Disease	niacinamide measurement	EXOC2 NAALADL2	3.61e-04	12	70	2	EFO_0010511
Disease	unipolar depression, bipolar disorder	LMAN2L TENM4 L3MBTL2 TENM2	5.25e-04	156	70	4	EFO_0003761, MONDO_0004985
Disease	depressive symptom measurement	AATK L3MBTL2 PSMB8 HERC1 NAALADL2 TENM2	5.26e-04	426	70	6	EFO_0007006
Disease	Manic Disorder	LMAN2L TENM4 NTRK1	6.51e-04	71	70	3	C0024713
Disease	Manic	LMAN2L TENM4 NTRK1	8.56e-04	78	70	3	C0338831
Disease	schizophrenia (is_implicated_in)	NTRK1 HPS4 CACNA1I	8.56e-04	78	70	3	DOID:5419 (is_implicated_in)
Disease	Depression, Bipolar	LMAN2L TENM4 NTRK1	8.89e-04	79	70	3	C0005587
Disease	obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa	LMAN2L L3MBTL2 CACNA1I TENM2	1.32e-03	200	70	4	EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Disease	L-arginine measurement	SLC38A4 HPS4	1.87e-03	27	70	2	EFO_0006524

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKWVILEKDFSIYGG	ACSBG2	626	Q5FVE4
FWDLLGGKTPYANDK	AVIL	591	O75366
YEGEFSDDWTLSGKG	ALS2	1221	Q96Q42
FWLLGDRGIKDEDGY	ACSM2A	441	Q08AH3
GGYLGILEWILGKKD	ASAH1	231	Q13510
KLGDKVAFYWEGNEP	ACSS2	116	Q9NR19
GGESYWGKPFKDEFR	PPIL2	341	Q13356
YDKDVGQWKERGIGD	RGPD5	1366	Q99666
YDKDVGQWKERGIGD	RGPD8	1366	O14715
WDKKGPGLYYVDEHG	PSMB8	176	P28062
LQFDGEGGWKFEKLD	ABCD1	671	P33897
GSKEYKVKAIGGIDW	FAT1	311	Q14517
LYIEWLDAFGEGKGK	SLC16A9	36	Q7RTY1
GSSKSKVGAWGDYDD	POTEF	111	A5A3E0
VLKWELGEGAFGKVF	NTRK1	511	P04629
GVFLNKYGFEGALWK	TRIM71	731	Q2Q1W2
RLWIEFDGEKGLDYG	NEDD4	991	P46934
FEGTLYKRGALLKGW	SBF2	1746	Q86WG5
VLGFDWGKFLKDHSY	L3MBTL2	176	Q969R5
ALTKDGQVYSWGKGD	HERC2	671	O95714
EGEVFSWGDGDYGKL	HERC1	476	Q15751
KFAIKVDGDYLWVLG	HPS4	81	Q9NQG7
ILGKGDVFGDIFWKE	KCNH5	606	Q8NCM2
ELKWEKGGSGLVFYT	GPATCH3	326	Q96I76
EYEKKHGSGDWRLLG	IRF2BPL	461	Q9H1B7
IRDGEAKQYGGWEVK	EXOC2	526	Q96KP1
KIKEWYDKYGPGSGD	KRT24	171	Q2M2I5
DKGWSFLLGKYISIG	LNPEP	871	Q9UIQ6
GKKNLHGDGLAIWYT	LMAN2L	121	Q9H0V9
EGKAVYRLFGKWHEG	OSBPL6	786	Q9BZF3
GTYSLGSGIKFDEWD	ELAPOR2	126	A8MWY0
KLGSGYFGEVFEGLW	PTK6	196	Q13882
DGKYEGLQEWEGKAH	APOB	3961	P04114
EVKGWGGEDVHLYRK	CSGALNACT2	451	Q8N6G5
DCEKGWALLKFGGKY	IFIT5	141	Q13325
DYFGKESLWTGKGIQ	BRCA2	2566	P51587
IKGGDVRDKWDQYKG	CHERP	871	Q8IWX8
ALGIFGKKCYLGDTW	CACNA1I	136	Q9P0X4
KKDVLDFGDLTYGGW	CEP192	1501	Q8TEP8
YLGDWGPEFKKLAEL	CDH18	766	Q13634
DKVFYSFLKPWLGDG	CYP4F3	121	Q08477
KGLALGIAKAWELYG	GSS	186	P48637
LGATGDLAKKYLWQG	H6PD	31	O95479
DFTGGIAEWYELKKP	CAPN2	206	P17655
KGWEFILPYDGEFIK	POLR3E	396	Q9NVU0
GTQVWKKKGAIYEGD	MORN3	51	Q6PF18
YDKDVGQWKERGIGD	RGPD1	1351	P0DJD0
REDLWAGSKGKEFGY	MIA2	76	Q96PC5
YHGWLFEGLGRDKAE	SLA	81	Q13239
GLDVKYFKPGDEVWA	RTN4IP1	131	Q8WWV3
LAKGEEEGWEYDTFG	FER1L5	971	A0AVI2
GFGGRYGVEKDKWDK	HCLS1	156	P14317
DKWDKAALGYDYKGE	HCLS1	166	P14317
LYLKEIGRGWFGKVF	AATK	126	Q6ZMQ8
YIWVGKGASQEEEKG	SCIN	551	Q9Y6U3
GFLGPWAKYVDEKDV	CDC40	191	O60508
VGLWHLAFYNDGKDK	TENM2	546	Q9NT68
CLLESWGKGEGLGYE	SETD1B	931	Q9UPS6
LIYEKLGEKAFGWPG	SLC38A4	136	Q969I6
GYFDQELKAWLLEKG	MRPL49	151	Q13405
NGIWKVYIDGKLSDG	SVEP1	1521	Q4LDE5
WSEKGDKDAEYGDKG	SIX6OS1	366	Q8N1H7
FWLLGDRGIKDEDGY	ACSM2B	441	Q68CK6
SSDEEGGLYEGKGWL	RGS12	106	O14924
RGGNSIWGKKFEDEY	PPIL3	61	Q9H2H8
EKGWRIGKGEGYADL	MTHFSD	146	Q2M296
YEIDASKLGGWSLDK	TENM4	1161	Q6N022
QGKKTIDIYWLFDDG	SLC12A3	826	P55017
DLYKWKDGSGEVGTT	WDR59	86	Q6PJI9
FGGTSVWYHVLKGEK	PHF8	286	Q9UPP1
GSLYNKGFKGERDHW	WSCD2	376	Q2TBF2
DKLIKIWGAYDGKFE	WDR5	66	P61964
IWGAYDGKFEKTISG	WDR5	71	P61964
FGNIGSYEWGEDFKK	NAALADL2	501	Q58DX5