Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylcholine flippase activity	ATP8B1 ATP10A	1.85e-04	6	71	2	GO:0140345
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ATP8B1 ATP10A	3.44e-04	8	71	2	GO:0090554
GeneOntologyMolecularFunction	heparin binding	THBS2 THBS3 COL5A3 F2 ITGAM	6.08e-04	192	71	5	GO:0008201
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8B1 PLSCR2 ATP10A	7.94e-04	51	71	3	GO:0140303
GeneOntologyMolecularFunction	axon guidance receptor activity	EPHB3 EPHB1	9.48e-04	13	71	2	GO:0008046
GeneOntologyMolecularFunction	pentosyltransferase activity	LARGE2 PARP1 TNKS2	1.04e-03	56	71	3	GO:0016763
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ATP8B1 ATP10A	1.10e-03	14	71	2	GO:0140333
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHB3 EPHB1	1.27e-03	15	71	2	GO:0005005
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LDLR SORL1	1.45e-03	16	71	2	GO:0005041
GeneOntologyMolecularFunction	FMN binding	NDOR1 NOS1	1.45e-03	16	71	2	GO:0010181
GeneOntologyMolecularFunction	floppase activity	ATP8B1 ATP10A	1.45e-03	16	71	2	GO:0140328
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	EPHB3 FLT4 EPHB1	1.61e-03	65	71	3	GO:0004714
GeneOntologyMolecularFunction	flippase activity	ATP8B1 ATP10A	1.64e-03	17	71	2	GO:0140327
GeneOntologyMolecularFunction	low-density lipoprotein particle binding	LDLR SORL1	1.84e-03	18	71	2	GO:0030169
GeneOntologyMolecularFunction	ephrin receptor activity	EPHB3 EPHB1	2.05e-03	19	71	2	GO:0005003
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ATP8B1 ATP10A	2.27e-03	20	71	2	GO:0008525
GeneOntologyMolecularFunction	phospholipid transporter activity	ATP8B1 PLSCR2 ATP10A	2.33e-03	74	71	3	GO:0005548
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LDLR SORL1	2.51e-03	21	71	2	GO:0030228
GeneOntologyMolecularFunction	glycosaminoglycan binding	THBS2 THBS3 COL5A3 F2 ITGAM	2.66e-03	268	71	5	GO:0005539
GeneOntologyMolecularFunction	cargo receptor activity	ITGAM LDLR SORL1	3.45e-03	85	71	3	GO:0038024
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	EPHB3 FLT4 EPHB1	3.45e-03	85	71	3	GO:0019199
GeneOntologyMolecularFunction	NADPH binding	NDOR1 NOS1	3.83e-03	26	71	2	GO:0070402
GeneOntologyMolecularFunction	NAD+-protein poly-ADP-ribosyltransferase activity	PARP1 TNKS2	4.44e-03	28	71	2	GO:0003950
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8B1 ATP10A	4.44e-03	28	71	2	GO:0140326
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THBS2 THBS3 COL5A3 ECM1	4.53e-03	188	71	4	GO:0005201
GeneOntologyMolecularFunction	chromatin binding	NCOA3 PHC3 PARP1 ZNF274 SMARCA1 CHD3 SVEP1 PHC2	4.62e-03	739	71	8	GO:0003682
GeneOntologyMolecularFunction	NAD+-protein ADP-ribosyltransferase activity	PARP1 TNKS2	5.08e-03	30	71	2	GO:1990404
GeneOntologyCellularComponent	extracellular matrix	MST1 FREM2 THBS2 THBS3 COL5A3 PLSCR2 F2 ECM1 SVEP1	3.67e-04	656	71	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	MST1 FREM2 THBS2 THBS3 COL5A3 PLSCR2 F2 ECM1 SVEP1	3.75e-04	658	71	9	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	MST1 FREM2 THBS2 THBS3 COL5A3 PLSCR2 F2 ECM1	4.24e-04	530	71	8	GO:0062023
HumanPheno	Anti-titin antibody positivity	PDCD1 ITGAM DNASE1	2.63e-04	30	22	3	HP:5000038
HumanPheno	Anti-complement component C1q antibody positivity	PDCD1 ITGAM DNASE1	2.63e-04	30	22	3	HP:0034077
HumanPheno	Anti-ribosome Po antibody positivity	PDCD1 ITGAM DNASE1	2.63e-04	30	22	3	HP:0034076
HumanPheno	Anti-phosphatidic acid antibody positivity	PDCD1 ITGAM DNASE1	2.63e-04	30	22	3	HP:0034096
HumanPheno	Anti-Ro52/TRIM21 antibody positivity	PDCD1 ITGAM DNASE1	2.63e-04	30	22	3	HP:0034093
HumanPheno	Anti-La/SS-B antibody positivity	PDCD1 ITGAM DNASE1	2.63e-04	30	22	3	HP:0032235
HumanPheno	Anti-nucleoporin 62 antibody positivity	PDCD1 ITGAM DNASE1	2.63e-04	30	22	3	HP:0033556
HumanPheno	Pyuria	PDCD1 ITGAM DNASE1	2.91e-04	31	22	3	HP:0012085
HumanPheno	Lupus nephritis	PDCD1 ITGAM DNASE1	3.20e-04	32	22	3	HP:0033726
HumanPheno	Anti-U1 ribonucleoprotein antibody positivity	PDCD1 ITGAM DNASE1	3.20e-04	32	22	3	HP:0033028
HumanPheno	Anti-Sm antibody positivity	PDCD1 ITGAM DNASE1	3.20e-04	32	22	3	HP:0033040
HumanPheno	Extractable nuclear antigen positivity	PDCD1 ITGAM DNASE1	3.84e-04	34	22	3	HP:0033476
HumanPheno	Anti-dsDNA antibody positivity	PDCD1 ITGAM DNASE1	3.84e-04	34	22	3	HP:0020151
HumanPheno	Decreased circulating complement C4 concentration	PDCD1 ITGAM DNASE1	4.19e-04	35	22	3	HP:0045042
MousePheno	decreased apoptosis	NCOA3 PARP1 THBS2 ZNF274 ITGAM NOS1 DNASE1	2.86e-05	219	57	7	MP:0006043
MousePheno	decreased cell death	NCOA3 PARP1 THBS2 ZNF274 ITGAM NOS1 DNASE1	3.21e-05	223	57	7	MP:0012555
Domain	Prothrombin/thrombin	MST1 F2	1.38e-05	2	70	2	IPR003966
Domain	SAM	EPHB3 PHC3 TNKS2 PHC2 EPHB1	1.97e-05	88	70	5	SM00454
Domain	SAM_DOMAIN	EPHB3 PHC3 TNKS2 PHC2 EPHB1	2.85e-05	95	70	5	PS50105
Domain	SAM	EPHB3 PHC3 TNKS2 PHC2 EPHB1	3.16e-05	97	70	5	IPR001660
Domain	-	EPHB3 PHC3 TNKS2 PHC2 EPHB1	4.83e-05	106	70	5	1.10.150.50
Domain	SAM/pointed	EPHB3 PHC3 TNKS2 PHC2 EPHB1	7.74e-05	117	70	5	IPR013761
Domain	TSPN	THBS2 THBS3 COL5A3	8.46e-05	23	70	3	SM00210
Domain	Ephrin_rec_like	EPHB3 SVEP1 EPHB1	1.09e-04	25	70	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB3 SVEP1 EPHB1	1.09e-04	25	70	3	IPR011641
Domain	SAM_1	EPHB3 PHC3 PHC2 EPHB1	1.23e-04	68	70	4	PF00536
Domain	Znf_FCS	PHC3 PHC2	1.37e-04	5	70	2	IPR012313
Domain	TSP_3	THBS2 THBS3	1.37e-04	5	70	2	PF02412
Domain	TSP3	THBS2 THBS3	1.37e-04	5	70	2	PS51234
Domain	TSP_CTER	THBS2 THBS3	1.37e-04	5	70	2	PS51236
Domain	-	THBS2 THBS3	1.37e-04	5	70	2	4.10.1080.10
Domain	Thrombospondin_C	THBS2 THBS3	1.37e-04	5	70	2	IPR008859
Domain	TSP_C	THBS2 THBS3	1.37e-04	5	70	2	PF05735
Domain	Thrombospondin_3_rpt	THBS2 THBS3	1.37e-04	5	70	2	IPR017897
Domain	Thrombospondin_3-like_rpt	THBS2 THBS3	1.37e-04	5	70	2	IPR003367
Domain	TSP_type-3_rpt	THBS2 THBS3	1.37e-04	5	70	2	IPR028974
Domain	FAD_binding_1	NDOR1 NOS1	2.06e-04	6	70	2	PF00667
Domain	ZF_FCS	PHC3 PHC2	2.06e-04	6	70	2	PS51024
Domain	FAD-binding_1	NDOR1 NOS1	2.06e-04	6	70	2	IPR003097
Domain	-	NDOR1 NOS1	2.06e-04	6	70	2	1.20.990.10
Domain	NADPH_Cyt_P450_Rdtase_dom3	NDOR1 NOS1	2.06e-04	6	70	2	IPR023173
Domain	Growth_fac_rcpt_	EPHB3 THBS3 LDLR SVEP1 EPHB1	2.98e-04	156	70	5	IPR009030
Domain	EGF_CA	THBS2 THBS3 LDLR SVEP1	3.05e-04	86	70	4	PF07645
Domain	FLAVODOXIN_LIKE	NDOR1 NOS1	3.82e-04	8	70	2	PS50902
Domain	Flavodoxin/NO_synth	NDOR1 NOS1	3.82e-04	8	70	2	IPR008254
Domain	Flavdoxin-like	NDOR1 NOS1	3.82e-04	8	70	2	IPR001094
Domain	Flavodoxin_1	NDOR1 NOS1	3.82e-04	8	70	2	PF00258
Domain	EGF-like_CS	THBS2 THBS3 LDLR SVEP1 SORL1 EPHB1	4.36e-04	261	70	6	IPR013032
Domain	-	THBS2 THBS3 COL5A3 SVEP1	4.45e-04	95	70	4	2.60.120.200
Domain	EGF_2	THBS2 THBS3 LDLR SVEP1 SORL1 EPHB1	4.73e-04	265	70	6	PS01186
Domain	Flavoprotein-like_dom	NDOR1 NOS1	6.11e-04	10	70	2	IPR029039
Domain	Flavoprot_Pyr_Nucl_cyt_Rdtase	NDOR1 NOS1	6.11e-04	10	70	2	IPR001709
Domain	-	NDOR1 NOS1	6.11e-04	10	70	2	3.40.50.360
Domain	Ephrin_rec_like	EPHB3 SVEP1	7.45e-04	11	70	2	PF07699
Domain	OxRdtase_FAD/NAD-bd	NDOR1 NOS1	8.92e-04	12	70	2	IPR001433
Domain	NAD_binding_1	NDOR1 NOS1	8.92e-04	12	70	2	PF00175
Domain	EGF_CA	THBS2 THBS3 LDLR SVEP1	1.14e-03	122	70	4	SM00179
Domain	EGF-like_Ca-bd_dom	THBS2 THBS3 LDLR SVEP1	1.21e-03	124	70	4	IPR001881
Domain	VWA	CACNA2D4 ITGAM SVEP1	1.21e-03	56	70	3	PF00092
Domain	RECEPTOR_TYR_KIN_V_2	EPHB3 EPHB1	1.22e-03	14	70	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB3 EPHB1	1.22e-03	14	70	2	PS00790
Domain	Eph_TM	EPHB3 EPHB1	1.22e-03	14	70	2	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHB3 EPHB1	1.22e-03	14	70	2	IPR001426
Domain	EPH_lbd	EPHB3 EPHB1	1.22e-03	14	70	2	SM00615
Domain	Ephrin_lbd	EPHB3 EPHB1	1.22e-03	14	70	2	PF01404
Domain	P_typ_ATPase_c	ATP8B1 ATP10A	1.22e-03	14	70	2	IPR032630
Domain	P-type_ATPase_N	ATP8B1 ATP10A	1.22e-03	14	70	2	IPR032631
Domain	EphA2_TM	EPHB3 EPHB1	1.22e-03	14	70	2	PF14575
Domain	Ldl_recept_b	LDLR SORL1	1.22e-03	14	70	2	PF00058
Domain	LDLRB	LDLR SORL1	1.22e-03	14	70	2	PS51120
Domain	Tyr_kinase_ephrin_rcpt	EPHB3 EPHB1	1.22e-03	14	70	2	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHB3 EPHB1	1.22e-03	14	70	2	IPR001090
Domain	EPH_LBD	EPHB3 EPHB1	1.22e-03	14	70	2	PS51550
Domain	P-type_ATPase_IV	ATP8B1 ATP10A	1.22e-03	14	70	2	IPR006539
Domain	PhoLip_ATPase_C	ATP8B1 ATP10A	1.22e-03	14	70	2	PF16212
Domain	PhoLip_ATPase_N	ATP8B1 ATP10A	1.22e-03	14	70	2	PF16209
Domain	Laminin_G	THBS2 THBS3 COL5A3	1.34e-03	58	70	3	IPR001791
Domain	LY	LDLR SORL1	1.41e-03	15	70	2	SM00135
Domain	LDLR_classB_rpt	LDLR SORL1	1.41e-03	15	70	2	IPR000033
Domain	Kringle	MST1 F2	1.82e-03	17	70	2	IPR000001
Domain	Poly(ADP-ribose)pol_cat_dom	PARP1 TNKS2	1.82e-03	17	70	2	IPR012317
Domain	PARP_CATALYTIC	PARP1 TNKS2	1.82e-03	17	70	2	PS51059
Domain	Kringle_CS	MST1 F2	1.82e-03	17	70	2	IPR018056
Domain	PARP	PARP1 TNKS2	1.82e-03	17	70	2	PF00644
Domain	KRINGLE_2	MST1 F2	1.82e-03	17	70	2	PS50070
Domain	Kringle	MST1 F2	1.82e-03	17	70	2	PF00051
Domain	KRINGLE_1	MST1 F2	1.82e-03	17	70	2	PS00021
Domain	-	PARP1 TNKS2	1.82e-03	17	70	2	3.90.228.10
Domain	KR	MST1 F2	1.82e-03	17	70	2	SM00130
Domain	EGF_3	THBS2 THBS3 LDLR SVEP1 SORL1	1.88e-03	235	70	5	PS50026
Domain	EGF	THBS2 THBS3 LDLR SVEP1 SORL1	1.88e-03	235	70	5	SM00181
Domain	-	R3HCC1L RBM12B PPRC1 U2SURP TMEM63B	2.22e-03	244	70	5	3.30.70.330
Domain	Fd_Rdtase_FAD-bd	NDOR1 NOS1	2.27e-03	19	70	2	IPR017927
Domain	FAD_FR	NDOR1 NOS1	2.27e-03	19	70	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	NDOR1 NOS1	2.27e-03	19	70	2	IPR017938
Domain	EGF-like_dom	THBS2 THBS3 LDLR SVEP1 SORL1	2.42e-03	249	70	5	IPR000742
Domain	Nucleotide-bd_a/b_plait	R3HCC1L RBM12B PPRC1 U2SURP TMEM63B	2.82e-03	258	70	5	IPR012677
Domain	VWFA	CACNA2D4 ITGAM SVEP1	3.61e-03	82	70	3	PS50234
Domain	WGR_domain	PARP1 TNKS2	3.62e-03	24	70	2	IPR008893
Pubmed	Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice.	ITGAM LDLR	4.11e-06	2	71	2	10884286
Pubmed	Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness.	TLR5 LDLR	4.11e-06	2	71	2	28202909
Pubmed	The nucleosome-remodeling ATPase ISWI is regulated by poly-ADP-ribosylation.	PARP1 SMARCA1	4.11e-06	2	71	2	18922045
Pubmed	Corneal stromal cells (keratocytes) express thrombospondins 2 and 3 in wound repair phenotype.	THBS2 THBS3	4.11e-06	2	71	2	11943589
Pubmed	CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mice.	ITGAM LDLR	4.11e-06	2	71	2	27234908
Pubmed	Relative abundance of thrombospondin 2 and thrombospondin 3 mRNAs in human tissues.	THBS2 THBS3	4.11e-06	2	71	2	10329465
Pubmed	Identification and characterisation of novel mammalian homologues of Drosophila polyhomeoticpermits new insights into relationships between members of the polyhomeotic family.	PHC3 PHC2	4.11e-06	2	71	2	12384788
Pubmed	Poly-(ADP-Ribose) Polymerase-1 Promotes Prothrombin Gene Transcription and Produces Des-Gamma-Carboxy Prothrombin in Hepatocellular Carcinoma.	PARP1 F2	4.11e-06	2	71	2	28384634
Pubmed	Association study of FLT4 and HYDIN single nucleotide polymorphisms with atrial septal defect susceptibility in the Han Chinese population of Southwest China.	FLT4 HYDIN	4.11e-06	2	71	2	38581027
Pubmed	Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection.	PARP1 NOS1	4.11e-06	2	71	2	15689952
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	PARP1 CIAO1 TMEM151B GART CHD3 LDLR EXOC8	5.34e-06	332	71	7	37433992
Pubmed	Programmed cell death-1 deficiency exacerbates T cell activation and atherogenesis despite expansion of regulatory T cells in atherosclerosis-prone mice.	PDCD1 LDLR	1.23e-05	3	71	2	24691202
Pubmed	Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction.	FLT4 LDLR	1.23e-05	3	71	2	30420641
Pubmed	Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation.	PDCD1 LDLR	1.23e-05	3	71	2	21393583
Pubmed	Lymphatic vessel insufficiency in hypercholesterolemic mice alters lipoprotein levels and promotes atherogenesis.	FLT4 LDLR	1.23e-05	3	71	2	24723556
Pubmed	mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.	THBS2 THBS3	1.23e-05	3	71	2	34669362
Pubmed	Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.	THBS2 THBS3	1.23e-05	3	71	2	1459996
Pubmed	Multiple EphB receptors mediate dorsal-ventral retinotopic mapping via similar bi-functional responses to ephrin-B1.	EPHB3 EPHB1	1.23e-05	3	71	2	25051176
Pubmed	Differential expression of thrombospondin 1, 2, and 3 during murine development.	THBS2 THBS3	1.23e-05	3	71	2	8400410
Pubmed	Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus.	EPHB3 EPHB1	1.23e-05	3	71	2	14691139
Pubmed	Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.	THBS2 THBS3	1.23e-05	3	71	2	9373030
Pubmed	A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development.	EPHB3 EPHB1	1.23e-05	3	71	2	23143520
Pubmed	A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families.	PDCD1 TLR5	1.23e-05	3	71	2	9843983
Pubmed	Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees.	PDCD1 TLR5	1.23e-05	3	71	2	9843982
Pubmed	Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.	PARP1 TNKS2	1.23e-05	3	71	2	33361107
Pubmed	EphB receptors couple dendritic filopodia motility to synapse formation.	EPHB3 EPHB1	1.23e-05	3	71	2	18614029
Pubmed	Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase.	EPHB3 EPHB1	1.23e-05	3	71	2	29731254
Pubmed	Investigating the effects of compound paralogous EPHB receptor mutations on mouse facial development.	EPHB3 EPHB1	1.23e-05	3	71	2	35025117
Pubmed	PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression.	PDCD1 PARP1	1.23e-05	3	71	2	28167507
Pubmed	A novel feedback mechanism by Ephrin-B1/B2 in T-cell activation involves a concentration-dependent switch from costimulation to inhibition.	EPHB3 EPHB1	1.23e-05	3	71	2	22622783
Pubmed	Retinal axon growth cones respond to EphB extracellular domains as inhibitory axon guidance cues.	EPHB3 EPHB1	1.23e-05	3	71	2	11532925
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	MST1 FREM2 FLT4 F2 ECM1 LDLR	1.47e-05	257	71	6	16335952
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	NCOA3 PHC3 PARP1 USP11 CEP76 TNKS2 CASZ1	1.73e-05	398	71	7	35016035
Pubmed	Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells.	FLT4 SVEP1	2.46e-05	4	71	2	37338522
Pubmed	EphB2 receptor forward signaling controls cortical growth cone collapse via Nck and Pak.	EPHB3 EPHB1	2.46e-05	4	71	2	23147113
Pubmed	Proatherogenic immune responses are regulated by the PD-1/PD-L pathway in mice.	PDCD1 LDLR	2.46e-05	4	71	2	17853943
Pubmed	Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors.	EPHB3 EPHB1	2.46e-05	4	71	2	22475621
Pubmed	Developmental regulation of LR11 expression in murine brain.	LDLR SORL1	2.46e-05	4	71	2	9726247
Pubmed	Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.	THBS2 THBS3	2.46e-05	4	71	2	6338048
Pubmed	Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling.	EPHB3 EPHB1	2.46e-05	4	71	2	21804545
Pubmed	Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families.	PDCD1 TLR5	2.46e-05	4	71	2	10677315
Pubmed	Null mutation of calpain 3 (p94) in mice causes abnormal sarcomere formation in vivo and in vitro.	CAPN3 ITGAM	2.46e-05	4	71	2	15138196
Pubmed	CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.	ITGAM LDLR	2.46e-05	4	71	2	17372166
Pubmed	Mac-1 Regulates IL-13 Activity in Macrophages by Directly Interacting with IL-13Rα1.	ITGAM LDLR	2.46e-05	4	71	2	26160172
Pubmed	Eph receptor deficiencies lead to altered cochlear function.	EPHB3 EPHB1	2.46e-05	4	71	2	12684184
Pubmed	Transcriptional signals of T-cell and corticosteroid-sensitive genes are associated with future acute cellular rejection in cardiac allografts.	PDCD1 ITGAM	2.46e-05	4	71	2	18096476
Pubmed	Nonredundant roles of keratinocyte-derived IL-34 and neutrophil-derived CSF1 in Langerhans cell renewal in the steady state and during inflammation.	NDOR1 ITGAM	2.46e-05	4	71	2	26634935
Pubmed	E7449: A dual inhibitor of PARP1/2 and tankyrase1/2 inhibits growth of DNA repair deficient tumors and antagonizes Wnt signaling.	PARP1 TNKS2	2.46e-05	4	71	2	26513298
Pubmed	GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking.	EPHB3 EPHB1	2.46e-05	4	71	2	15965473
Pubmed	In Vitro Analysis of the Expression of CD11, CD29, CD36, and DC-STAMP Molecules during the Formation of Multinuclear Macrophages in BCG-Infected Mice.	DCSTAMP ITGAM	2.46e-05	4	71	2	31641985
Pubmed	The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.	RBM12B TNKS2 EXOC8	3.18e-05	30	71	3	30480076
Pubmed	Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.	THBS2 THBS3	4.09e-05	5	71	2	30622267
Pubmed	ANXA1 Promotes Tumor Immune Evasion by Binding PARP1 and Upregulating Stat3-Induced Expression of PD-L1 in Multiple Cancers.	PDCD1 PARP1	4.09e-05	5	71	2	37566399
Pubmed	Enhanced egg-induced immunopathology correlates with high IFN-gamma in murine schistosomiasis: identification of two epistatic genetic intervals.	PARP1 TLR5	4.09e-05	5	71	2	15611268
Pubmed	Vascular endothelial growth factor-C derived from CD11b+ cells induces therapeutic improvements in a murine model of hind limb ischemia.	FLT4 ITGAM	4.09e-05	5	71	2	23219511
Pubmed	Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.	ATP8B1 ATP10A	4.09e-05	5	71	2	9548971
Pubmed	Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping.	EPHB3 EPHB1	4.09e-05	5	71	2	21847105
Pubmed	Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex.	EPHB3 EPHB1	4.09e-05	5	71	2	21559471
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	PARP1 RBM12B ACTBL2 SIPA1L3 U2SURP GART SMARCA1 F2	5.99e-05	660	71	8	32780723
Pubmed	EphB1 and EphB2 intracellular domains regulate the formation of the corpus callosum and anterior commissure.	EPHB3 EPHB1	6.13e-05	6	71	2	26148571
Pubmed	Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling.	PARP1 TNKS2	6.13e-05	6	71	2	21799911
Pubmed	Quantitative trait analysis of the development of pulmonary tolerance to inhaled zinc oxide in mice.	PARP1 TLR5	6.13e-05	6	71	2	16026622
Pubmed	Distribution of EphB receptors and ephrin-B1 in the developing vertebrate spinal cord.	EPHB3 EPHB1	6.13e-05	6	71	2	16786562
Pubmed	Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning.	EPHB3 EPHB1	6.13e-05	6	71	2	19182796
Pubmed	Abnormal hippocampal axon bundling in EphB receptor mutant mice.	EPHB3 EPHB1	6.13e-05	6	71	2	15014111
Pubmed	Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics.	ATP8B1 ATP10A	6.13e-05	6	71	2	25947375
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	EPHB3 FLT4 EPHB1	7.63e-05	40	71	3	30898150
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ENGASE NDOR1 PPRC1 CHCHD5 SIPA1L3 DISP2 FAM110A LDLR CASZ1 PHC2	8.01e-05	1105	71	10	35748872
Pubmed	Molecular mechanisms controlling the migration of striatal interneurons.	EPHB3 EPHB1	8.57e-05	7	71	2	26063906
Pubmed	EphB regulates L1 phosphorylation during retinocollicular mapping.	EPHB3 EPHB1	8.57e-05	7	71	2	22579729
Pubmed	Similarities and Differences in the Way Transmembrane-Type Ligands Interact with the Elk Subclass of Eph Receptors.	EPHB3 EPHB1	8.57e-05	7	71	2	8954633
Pubmed	Forward signaling by EphB1/EphB2 interacting with ephrin-B ligands at the optic chiasm is required to form the ipsilateral projection.	EPHB3 EPHB1	8.57e-05	7	71	2	22103419
Pubmed	Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.	MST1 ECM1	1.14e-04	8	71	2	18438406
Pubmed	3D Mapping Reveals a Complex and Transient Interstitial Matrix During Murine Kidney Development.	FREM2 COL5A3	1.14e-04	8	71	2	33875569
Pubmed	Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.	THBS2 THBS3	1.14e-04	8	71	2	24460873
Pubmed	Mis-expression of L1 on pre-crossing spinal commissural axons disrupts pathfinding at the ventral midline.	EPHB3 EPHB1	1.14e-04	8	71	2	17884558
Pubmed	An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.	FLT4 SVEP1	1.14e-04	8	71	2	28179432
Pubmed	Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons.	EPHB3 EPHB1	1.47e-04	9	71	2	10704386
Pubmed	Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.	EPHB3 EPHB1	1.47e-04	9	71	2	11403717
Pubmed	The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.	USP11 USP25	1.47e-04	9	71	2	22195557
Pubmed	A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.	SMARCA1 CHD3	1.47e-04	9	71	2	16728976
Pubmed	Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion.	EPHB3 EPHB1	1.47e-04	9	71	2	18713744
Pubmed	EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis.	EPHB3 EPHB1	1.47e-04	9	71	2	33253166
Pubmed	EphB/syndecan-2 signaling in dendritic spine morphogenesis.	EPHB3 EPHB1	1.47e-04	9	71	2	11580899
Pubmed	Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.	LDLR SORL1	1.47e-04	9	71	2	20005821
Pubmed	Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina.	EPHB3 EPHB1	1.47e-04	9	71	2	10683176
Pubmed	Volumetric imaging reveals VEGF-C-dependent formation of hepatic lymph vessels in mice.	FLT4 LDLR	1.47e-04	9	71	2	36051444
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	PARP1 ACTBL2 GART BMS1 TNKS2	1.82e-04	256	71	5	32698014
Pubmed	Aberrant cell segregation in the craniofacial primordium and the emergence of facial dysmorphology in craniofrontonasal syndrome.	EPHB3 EPHB1	1.83e-04	10	71	2	32092051
Pubmed	The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.	ATP8B1 ATP10A	1.83e-04	10	71	2	15919184
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	FREM2 COL5A3	1.83e-04	10	71	2	15345741
Pubmed	EphB signaling regulates target innervation in the developing and deafferented auditory brainstem.	EPHB3 EPHB1	1.83e-04	10	71	2	22021100
Pubmed	Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling.	EPHB3 EPHB1	1.83e-04	10	71	2	25923646
Pubmed	Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling.	FLT4 ITGAM	1.83e-04	10	71	2	27464987
Pubmed	EphB2 guides axons at the midline and is necessary for normal vestibular function.	EPHB3 EPHB1	1.83e-04	10	71	2	10839360
Pubmed	Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence- and preoptic area-derived interneurons in the deep and superficial migratory stream.	EPHB3 EPHB1	2.23e-04	11	71	2	22171039
Pubmed	Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism.	EPHB3 EPHB1	2.23e-04	11	71	2	19515977
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	CAPN3 OSBPL7 F2 LDLR	2.33e-04	146	71	4	20686565
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	PARP1 ACTBL2 U2SURP SMARCA1 CHD3	2.37e-04	271	71	5	32433965
Pubmed	USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair.	PARP1 USP11	2.68e-04	12	71	2	31504778
Cytoband	1q41-q42	PARP1 TLR5	2.35e-05	5	71	2	1q41-q42
GeneFamily	Sterile alpha motif domain containing	EPHB3 PHC3 TNKS2 PHC2 EPHB1	2.85e-06	88	46	5	760
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB3 EPHB1	5.65e-04	14	46	2	1095
GeneFamily	ATPase phospholipid transporting	ATP8B1 ATP10A	6.51e-04	15	46	2	1210
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP1 TNKS2	8.41e-04	17	46	2	684
ToppCell	facs-Lung-EPCAM-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF8 CYP4B1 CHCHD5 SHCBP1 DISP2 DNASE1	1.81e-07	155	71	6	0e942609d3e060f1e589fee5997fc6299f3d18bc
ToppCell	facs-Lung-EPCAM-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 CHCHD5 SHCBP1 DISP2 DNASE1	5.09e-06	156	71	5	bb64bf520cb74897a01c64924a85a1550df2b801
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 ATP8B1 ALS2CL ATP10A CASZ1	1.10e-05	183	71	5	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 ATP8B1 ALS2CL ATP10A CASZ1	1.10e-05	183	71	5	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	facs-Brain_Non-Myeloid-Striatum_\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 CYP4B1 CAPN3 TLR5 ITGAM	1.10e-05	183	71	5	824ecda1219fb596a01bf5cfeee29a6daa462098
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 CYP4B1 CAPN3 TLR5 ITGAM	1.10e-05	183	71	5	82b84ee065fb573688d59da97a327152a1ba294c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 ATP8B1 ALS2CL ATP10A CASZ1	1.13e-05	184	71	5	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 ECM1 SVEP1	1.29e-05	189	71	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 ECM1 SVEP1	1.32e-05	190	71	5	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 ECM1 SVEP1	1.32e-05	190	71	5	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS2 THBS3 SMARCA1 SVEP1 TENT5B	1.36e-05	191	71	5	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3\|TCGA-Ovary / Sample_Type by Project: Shred V9	THBS2 COL5A3 ATP8B1 ECM1 ATP10A	1.36e-05	191	71	5	80d30d8eedb4c70b58440646325bc04c5700803e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS3 COL5A3 ATP8B1 ECM1 SVEP1	1.39e-05	192	71	5	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	(3)_Chondrocytes-(30)_Chondro\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	NOTUM CYP4B1 CHD3 PDE7B SORL1	1.50e-05	195	71	5	f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	EPHB3 LARGE2 CYP4B1 TMEM63B LDLR	1.69e-05	200	71	5	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	droplet-Heart-HEART-1m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF8 ENGASE SIPA1L3 EPHB1	2.07e-05	101	71	4	6c4524be89cf3eb06769c2963dcded3da1e71ca0
ToppCell	LPS-antiTNF-Myeloid-Dendritic_cells-pDC\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDCD1 ATP10A CLEC4C EPHB1	5.40e-05	129	71	4	454bae525f6db3d0dd6347d2a2c3ea9dda9cd212
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 DNASE1	9.69e-05	150	71	4	96b160f163030fbf48aedc37d6ae224e11492c52
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHCBP1 CHD3 ATP8B1 CASZ1	9.95e-05	151	71	4	10da94037225a71844281ddcb395072250a78094
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLT4 CYP4B1 ECM1 CASZ1	1.07e-04	154	71	4	212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GART TMEM63B COL5A3 PLSCR2	1.10e-04	155	71	4	82e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GART TMEM63B COL5A3 PLSCR2	1.10e-04	155	71	4	979c1d53b435a82c57d16707eed8ba7346326866
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	DCSTAMP ITGAM CASZ1 SORL1	1.13e-04	156	71	4	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	facs-GAT-Fat-24m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 CACNA2D4 CYP4B1 PLSCR2	1.16e-04	157	71	4	c4a0b6c95d353691fd2846002ce4bc7c2b0edd1c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL5A3 F2 ECM1 SVEP1	1.18e-04	158	71	4	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	PPRC1 SIPA1L3 OSBPL7 LDLR	1.21e-04	159	71	4	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-pDC\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDCD1 ATP10A CLEC4C EPHB1	1.24e-04	160	71	4	dee756a2dc9725520d439e7273c489c2284015d8
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	PDCD1 SMARCA1 PDE7B TENT5B	1.37e-04	164	71	4	334f376350c9cf92611d0f75b2e18a102f4c116a
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM12B CAPN3 ECM1 ATP10A	1.43e-04	166	71	4	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM12B CAPN3 ECM1 ATP10A	1.43e-04	166	71	4	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL5A3 ATP10A SVEP1 SORL1	1.57e-04	170	71	4	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	EPHB3 GART ITGAM PDE7B	1.60e-04	171	71	4	26b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 PLSCR2 F2 CASZ1	1.68e-04	173	71	4	2a5ea28c65dd4ee03ba3d0bfe0c819b1d583f8da
ToppCell	droplet-Fat-Scat-21m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 ATP8B1 PLSCR2 EXOC8	1.68e-04	173	71	4	f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	ZNF8 PDCD1 OSBPL7 PDE7B	1.68e-04	173	71	4	e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MST1 SHCBP1 DCSTAMP TENT5B	1.68e-04	173	71	4	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 PLSCR2 F2 CASZ1	1.68e-04	173	71	4	6a7e4fa2d9d00f50decc89b535d8a68ec96de58a
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FLT4 ATP8B1 CASZ1 EPHB1	1.72e-04	174	71	4	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	facs-Spleen-nan-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 KCND1 CHD3 FAM110A	1.72e-04	174	71	4	096bc6f1889f2bbadfe1e1a3eb6ae569aaa2ee7d
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FLT4 TLR5 SMARCA1	1.75e-04	175	71	4	9d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FLT4 TLR5 SMARCA1	1.75e-04	175	71	4	f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell	facs-Heart-RV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ALS2CL	1.79e-04	176	71	4	fb3d03f64592e1df1d9785d9f2e70938d7ff9ce8
ToppCell	facs-Heart-RV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ALS2CL	1.79e-04	176	71	4	3270a36fc91a5583646ffeb70bfcbc5af7292aac
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ALS2CL	1.79e-04	176	71	4	a3f27b5d7edf2d396c085efbe35305cfa0afa565
ToppCell	facs-Pancreas-Endocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	1.79e-04	176	71	4	9ddf87e586d2378984cd007c60f7dc254845f8f3
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 HYDIN	1.79e-04	176	71	4	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	facs-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	1.79e-04	176	71	4	e987e741fcf1bed8598a5060700efd3018f8123b
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	THBS2 THBS3 COL5A3 ECM1	1.79e-04	176	71	4	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF8 CACNA2D4 CYP4B1 TLR5	1.79e-04	176	71	4	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF8 CACNA2D4 CYP4B1 TLR5	1.79e-04	176	71	4	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	facs-Pancreas-Endocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	1.79e-04	176	71	4	92ebcea9b2b22601234b76d7a98f0410b905a87b
ToppCell	facs-Heart-RV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ALS2CL	1.79e-04	176	71	4	99410c121f55adbc7fcc013c8fa8905a45dba76b
ToppCell	facs-Lung-EPCAM-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 PLSCR2 ALS2CL CASZ1	1.83e-04	177	71	4	2433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 RBM12B PLSCR2 EPHB1	1.87e-04	178	71	4	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	FLT4 ITGAM ATP10A SVEP1	1.91e-04	179	71	4	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	facs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 PLSCR2 ALS2CL CASZ1	1.95e-04	180	71	4	082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 PLSCR2 ALS2CL CASZ1	1.95e-04	180	71	4	53043d764fad9ac33ee40e356e562e759931adef
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS2 COL5A3 PDE7B SVEP1	2.04e-04	182	71	4	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYP4B1 TMEM63B ALS2CL ATP10A	2.08e-04	183	71	4	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	Basal\|World / shred by cell class for mouse tongue	LARGE2 FREM2 SIPA1L3 ECM1	2.08e-04	183	71	4	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 SVEP1	2.08e-04	183	71	4	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 SVEP1	2.08e-04	183	71	4	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 SVEP1	2.08e-04	183	71	4	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB3 THBS3 ZNF274 KCND1	2.12e-04	184	71	4	d754c3de621429b220ae4ac426cdfc619e848462
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LARGE2 FREM2 CYP4B1 SORL1	2.12e-04	184	71	4	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 SVEP1	2.17e-04	185	71	4	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Pancreas-Endocrine-24m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	2.17e-04	185	71	4	7f9121bbff3471982aa8706a599922c2d28e6e9b
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 SVEP1	2.17e-04	185	71	4	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 SVEP1	2.17e-04	185	71	4	a94694e226856bc5b168464f52d76004145717a5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 FREM2 COL5A3 HYDIN	2.17e-04	185	71	4	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	CYP4B1 SIPA1L3 ALS2CL ATP10A	2.17e-04	185	71	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	facs-Pancreas-Endocrine-24m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	2.17e-04	185	71	4	8159e0aef2c8826e0deac6fdc90505ac0400ba2b
ToppCell	facs-Pancreas-Endocrine-24m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	2.17e-04	185	71	4	8626fb015cfa20c847661b74ef51ca0dfd1025e0
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	NCOA3 NOTUM SIPA1L3 DNASE1	2.21e-04	186	71	4	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	ENGASE COL5A3 ATP8B1 SVEP1	2.21e-04	186	71	4	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	NCOA3 NOTUM SIPA1L3 DNASE1	2.21e-04	186	71	4	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	facs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4B1 ALS2CL CASZ1 TENT5B	2.26e-04	187	71	4	fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 NOS1 ATP10A HYDIN	2.31e-04	188	71	4	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS3 COL5A3 ATP8B1 ECM1	2.31e-04	188	71	4	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ALS2CL	2.31e-04	188	71	4	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	droplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FLT4 SMARCA1 EPHB1	2.31e-04	188	71	4	a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 FLT4 SMARCA1 EPHB1	2.31e-04	188	71	4	54550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCell	facs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ALS2CL	2.31e-04	188	71	4	e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHCBP1 ATP8B1 PDE7B CASZ1	2.31e-04	188	71	4	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	facs-Heart-LV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ALS2CL	2.31e-04	188	71	4	0fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FREM2 SIPA1L3 HYDIN CASZ1	2.31e-04	188	71	4	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	droplet-Heart-HEART-1m-Hematologic-erythrocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF8 ENGASE EPHB1	2.34e-04	75	71	3	f1ad409d1b2c5f23bf2b22137e612d627c041b97
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 THBS3 COL5A3 ECM1	2.35e-04	189	71	4	544d95df910f1b276995624509a7e41b219baca0
ToppCell	droplet-Pancreas-Endocrine-21m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	2.35e-04	189	71	4	37ce47abd6f96df04d35a4a6189d007bef5ccc94
ToppCell	droplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	2.35e-04	189	71	4	b55324cb365a827d071952709bbf0e8ef8c313de
ToppCell	droplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 CYP4B1 PLSCR2 ECM1	2.35e-04	189	71	4	62e46d59d3b89d4566b595c704d8b02f1ea9060b
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS3 COL5A3 ECM1 LDLR	2.35e-04	189	71	4	0a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	DPP9 SIPA1L3 TMEM63B CASZ1	2.35e-04	189	71	4	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS2 FLT4 SMARCA1 EPHB1	2.40e-04	190	71	4	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 COL5A3 ECM1 SVEP1	2.40e-04	190	71	4	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS2 FLT4 SMARCA1 EPHB1	2.40e-04	190	71	4	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 COL5A3 ECM1 SVEP1	2.40e-04	190	71	4	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 COL5A3 ECM1 SVEP1	2.40e-04	190	71	4	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS2 FLT4 SMARCA1 EPHB1	2.40e-04	190	71	4	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHCBP1 ATP8B1 PDE7B CASZ1	2.40e-04	190	71	4	11d3c31167ea71809b4cc3757a0c6ea54a448602
Disease	Systemic lupus erythematosus	PDCD1 TLR5 DNASE1	1.82e-06	11	67	3	cv:C0024141
Disease	Libman-Sacks Disease	PDCD1 TLR5 ITGAM DNASE1	9.39e-06	58	67	4	C0242380
Disease	systemic lupus erythematosus (is_implicated_in)	PDCD1 TLR5 F2 DNASE1	1.23e-05	62	67	4	DOID:9074 (is_implicated_in)
Disease	Lupus Erythematosus, Systemic	PDCD1 TLR5 ITGAM DNASE1	2.10e-05	71	67	4	C0024141
Disease	atherosclerosis (implicated_via_orthology)	F2 LDLR	1.06e-04	7	67	2	DOID:1936 (implicated_via_orthology)
Disease	Alzheimer's disease (is_implicated_in)	PARP1 NOS1 LDLR SORL1	2.36e-04	132	67	4	DOID:10652 (is_implicated_in)
Disease	autoimmune hepatitis (is_marker_for)	F2 DNASE1	2.76e-04	11	67	2	DOID:2048 (is_marker_for)
Disease	autoimmune hepatitis (is_implicated_in)	PDCD1 F2	3.90e-04	13	67	2	DOID:2048 (is_implicated_in)
Disease	cortisol measurement, response to corticosteroid, response to synacthen	NOS1 PDE7B	3.90e-04	13	67	2	EFO_0005843, EFO_0009175, GO_0031960
Disease	hyperglycemia (is_marker_for)	F2 ITGAM	3.90e-04	13	67	2	DOID:4195 (is_marker_for)
Disease	transient cerebral ischemia (implicated_via_orthology)	PARP1 ITGAM NOS1	4.22e-04	64	67	3	DOID:224 (implicated_via_orthology)
Disease	Prostatic Neoplasms	NCOA3 PARP1 TLR5 SMARCA1 COL5A3 CHD3 CASZ1	4.91e-04	616	67	7	C0033578
Disease	Malignant neoplasm of prostate	NCOA3 PARP1 TLR5 SMARCA1 COL5A3 CHD3 CASZ1	4.91e-04	616	67	7	C0376358
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	PARP1 TLR5	6.76e-04	17	67	2	DOID:8677 (biomarker_via_orthology)
Disease	lupus nephritis (is_implicated_in)	PDCD1 ITGAM	7.59e-04	18	67	2	DOID:0080162 (is_implicated_in)
Disease	parahippocampal gyrus volume measurement	EPHB3 FREM2	7.59e-04	18	67	2	EFO_0010318
Disease	toxic shock syndrome (is_marker_for)	PDCD1 F2	8.47e-04	19	67	2	DOID:14115 (is_marker_for)
Disease	end stage renal disease (implicated_via_orthology)	F2 NOS1	9.40e-04	20	67	2	DOID:783 (implicated_via_orthology)
Disease	prothrombin time measurement	FAM110A F2	1.04e-03	21	67	2	EFO_0008390
Disease	Obesity	PARP1 F2 ITGAM LDLR	1.23e-03	205	67	4	C0028754
Disease	pre-eclampsia (is_implicated_in)	F2 ITGAM	1.47e-03	25	67	2	DOID:10591 (is_implicated_in)
Disease	cystic fibrosis (is_implicated_in)	TLR5 NOS1	1.72e-03	27	67	2	DOID:1485 (is_implicated_in)
Disease	creatinine measurement	THBS3 USP11 SIPA1L3 FAM110A LDLR CASZ1 PHC2 SORL1	1.82e-03	995	67	8	EFO_0004518
Disease	hepatitis C (is_implicated_in)	PDCD1 LDLR	1.85e-03	28	67	2	DOID:1883 (is_implicated_in)
Disease	vital capacity	EPHB3 NCOA3 THBS2 R3HCC1L DISP2 ATE1 DNASE1 CASZ1 SVEP1	1.85e-03	1236	67	9	EFO_0004312
Disease	triglyceride measurement, intermediate density lipoprotein measurement	CAPN3 TNKS2 LDLR	2.08e-03	111	67	3	EFO_0004530, EFO_0008595
Disease	cancer	PHC3 PARP1 CHD3 ATP8B1 ATE1	2.17e-03	400	67	5	MONDO_0004992

Protein segments in the cluster

Peptide	Gene	Start	Entry
FRDFVCAGCPRDLQE	ALS2CL	606	Q60I27
IGNERFRCPEAIFQP	ACTBL2	251	Q562R1
LINDGFQRFRATEDC	CASZ1	581	Q86V15
NEEFQDAIRRAVPDG	CEP76	576	Q8TAP6
ELGGLFRVNQPDREC	BMS1	711	Q14692
VEPLEDRRQENFFCG	DISP2	266	A7MBM2
GFIECEEPNNRLDKF	ATP8B1	261	O43520
GDFVRLRCNEIFPAD	ATP10A	166	O60312
DFGPRDERDNFVQND	RBFA	201	Q8N0V3
FNDDGDCLDPRLLQE	R3HCC1L	581	Q7Z5L2
QEEDFRCPSDEDFRQ	RBM12B	831	Q8IXT5
LDEEDPCFEFRQQQL	LARGE2	396	Q8N3Y3
GCFVKNREELGFRPE	PARP1	161	P09874
SRCDDNVEFVPRQLG	EPHB1	371	P54762
PRQECIQAFDEELAF	KCND1	106	Q9NSA2
EFAFQPETEECRVGI	FREM2	206	Q5SZK8
AFPEDRSQPGQDCRF	PDCD1	81	Q15116
DADNFGIQFPRDLDV	PLSCR2	261	Q9NRY7
VERCGEILFENPDQN	PDE7B	6	Q9NP56
FVQFDERERHQQRPC	DCSTAMP	251	Q9H295
DLERFFNFCGLDPEE	FAM110A	201	Q9BQ89
RCDDNVEFVPRQLGL	EPHB3	391	P54753
CNNFRDFIERENLQP	JRKL	156	Q9Y4A0
PEDLDVCIAQRDFEG	EXOC8	341	Q8IYI6
LPGCQDIADEFRAQE	PHC3	931	Q8NDX5
AQGQEELFEYCNRPR	NDOR1	336	Q9UHB4
NRIQADELVPCFVRG	NOS1	1221	P29475
VVPERCRRQFQEGEE	NOTUM	301	Q6P988
PFEAFEECLRQNEAA	CHCHD5	61	Q9BSY4
CETEIFEVRFDPQGA	HYDIN	1651	Q4G0P3
PQSEGEDELCFLRAN	DPP9	431	Q86TI2
PDENGVITFDCRNRG	CACNA2D4	266	Q7Z3S7
PERFNNLEGFLEEFA	CHD3	931	Q12873
CGNDTFNREPAIVRF	DNASE1	126	P24855
AEAAIRFECVFLPDN	TMEM63B	551	Q5T3F8
CRFNQDPEAVDEDRS	ATE1	451	O95260
CREEVREILGDQDFF	CYP4B1	341	P13584
RQGEARFSCFQEEAP	ECM1	261	Q16610
EDGFNVALEPLACRQ	ENGASE	101	Q8NFI3
DLRENFCRNPDGSEA	MST1	326	P26927
CENPRFIIDGANRTD	CAPN3	106	P20807
QADEQPFDLCFGGRR	PPRC1	1606	Q5VV67
IDPNQGCARDSFRVF	COL5A3	1561	P25940
RENGDPQLCDFLEND	FTH1P19	86	P0C7X4
CERPDRGFRFISEQV	OSBPL7	566	Q9BZF2
GVPRCQDDRDVFALA	MEIOC	871	A2RUB1
FNGEDFDRPVVVSNC	SORL1	661	Q92673
EELRQCVRNAPQFRF	SMARCA1	986	P28370
CQRARFFAENEGLDD	TMEM151B	251	Q8IW70
PGFEDIIRRCIQRFF	NCOA3	291	Q9Y6Q9
ILNEFRSEQPDARGC	SIPA1L3	221	O60292
RLCQEPGEEEREIQF	SHCBP1	351	Q8NEM2
FNPREVARNVFECND	ITGAM	626	P11215
QCEPGYELEGNRERV	SVEP1	3266	Q4LDE5
CSRFFIDFPDLVEQR	TENT5B	306	Q96A09
DEERARERNCGFVAF	U2SURP	311	O15042
CGDDAIRVFQEDPNS	CIAO1	271	O76071
GEPNNLDERCAIINF	CLEC4C	171	Q8WTT0
LPGCQEIAEEFRAQE	PHC2	806	Q8IXK0
RPFECQECGRTFNDR	ZNF274	561	Q96GC6
PGVQINEEFCQRLRD	FLT4	1116	P35916
LEQFGDRNLSFDERC	USP25	826	Q9UHP3
CNDTVPEDFEPFRRQ	THBS3	936	P49746
VLEFNCRFGDPECQV	GART	286	P22102
VEPAARELFEACRNG	TNKS2	21	Q9H2K2
GEKPFECRQRLIFEQ	ZNF8	421	P17098
QLVENFCRNPDGDEE	F2	256	P00734
NCRLVFNPDQEDLDG	THBS2	911	P35442
NLCFEERDFVPGENR	TLR5	726	O60602
LCFRFRDQNPEVAVE	USP11	11	P51784
PDGFQLVAQRRCEDI	LDLR	341	P01130