Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC22A6 SLC26A3 SLC26A7

4.30e-0531443GO:0005310
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC22A6 SLC26A3 SLC26A7

4.73e-0532443GO:0005452
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC22A6 SLC36A3 SLC26A3 SLC26A7 SLCO2B1

8.92e-05207445GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC22A6 SLC36A3 SLC26A3 SLC26A7 SLCO2B1

9.12e-05208445GO:0005342
GeneOntologyMolecularFunctiontransmembrane transporter activity

PEX2 KCNS1 SLC22A6 SLC36A3 SLC26A3 ABCA5 SLC26A7 SLCO2B1 SLC25A51 CHRNE

1.96e-0411804410GO:0022857
GeneOntologyMolecularFunctionoxalate transmembrane transporter activity

SLC26A3 SLC26A7

2.11e-0410442GO:0019531
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A3 SLC26A7

3.64e-0413442GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A3 SLC26A7

3.64e-0413442GO:0140829
GeneOntologyMolecularFunctiontransporter activity

PEX2 KCNS1 SLC22A6 SLC36A3 SLC26A3 ABCA5 SLC26A7 SLCO2B1 SLC25A51 CHRNE

3.99e-0412894410GO:0005215
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLC22A6 SLCO2B1

4.25e-0414442GO:0015132
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC22A6 SLC36A3 SLC26A3 SLC26A7 SLCO2B1

4.47e-04293445GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC22A6 SLC36A3 SLC26A3 SLC26A7 SLCO2B1

4.68e-04296445GO:0015291
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLC22A6 SLCO2B1

4.89e-0415442GO:0071714
GeneOntologyMolecularFunctionsulfate transmembrane transporter activity

SLC26A3 SLC26A7

5.58e-0416442GO:0015116
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC22A6 SLC36A3 SLC26A3 ABCA5 SLC26A7 SLCO2B1

5.89e-04477446GO:0022804
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLC22A6 SLCO2B1

7.10e-0418442GO:0015347
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC26A3 SLC26A7

2.26e-0332442GO:0015106
GeneOntologyMolecularFunctionantiporter activity

SLC22A6 SLC26A3 SLC26A7

3.48e-03138443GO:0015297
DomainARM-like

SCYL2 DOCK10 RANBP17 IPO13 NCAPD3 NEK10

3.84e-05270446IPR011989
Domain-

SCYL2 RANBP17 IPO13 NCAPD3 NEK10

1.69e-042224451.25.10.10
DomainSLC26A

SLC26A3 SLC26A7

2.41e-0410442PS01130
DomainSTAS

SLC26A3 SLC26A7

2.94e-0411442PS50801
DomainSLC26A/SulP_fam

SLC26A3 SLC26A7

2.94e-0411442IPR001902
DomainSTAS_dom

SLC26A3 SLC26A7

2.94e-0411442IPR002645
Domain-

SLC26A3 SLC26A7

2.94e-04114423.30.750.24
DomainSLC26A/SulP_dom

SLC26A3 SLC26A7

2.94e-0411442IPR011547
DomainSulfate_transp

SLC26A3 SLC26A7

2.94e-0411442PF00916
DomainSTAS

SLC26A3 SLC26A7

2.94e-0411442PF01740
DomainHEAT

SCYL2 IPO13 NCAPD3

3.44e-0458443IPR000357
DomainIBN_N

RANBP17 IPO13

5.59e-0415442PF03810
DomainHEAT_REPEAT

SCYL2 IPO13 NCAPD3

5.98e-0470443PS50077
DomainIBN_N

RANBP17 IPO13

6.37e-0416442SM00913
DomainImportin-beta_N

RANBP17 IPO13

7.21e-0417442IPR001494
DomainARM-type_fold

SCYL2 RANBP17 IPO13 NCAPD3 NEK10

1.16e-03339445IPR016024
DomainHormR

SCTR CRHR2

1.57e-0325442SM00008
DomainHRM

SCTR CRHR2

1.97e-0328442PF02793
DomainGPCR_2_secretin-like_CS

SCTR CRHR2

2.90e-0334442IPR017983
DomainG_PROTEIN_RECEP_F2_1

SCTR CRHR2

4.00e-0340442PS00649
DomainG_PROTEIN_RECEP_F2_3

SCTR CRHR2

4.00e-0340442PS50227
DomainGPCR_2_extracellular_dom

SCTR CRHR2

4.00e-0340442IPR001879
DomainHEAT

SCYL2 NCAPD3

5.71e-0348442PF02985
DomainG_PROTEIN_RECEP_F2_2

SCTR CRHR2

6.18e-0350442PS00650
Domain7tm_2

SCTR CRHR2

6.18e-0350442PF00002
DomainGPCR_2-like

SCTR CRHR2

8.80e-0360442IPR017981
DomainGPCR_2_secretin-like

SCTR CRHR2

8.80e-0360442IPR000832
DomainG_PROTEIN_RECEP_F2_4

SCTR CRHR2

9.09e-0361442PS50261
PathwayREACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS

SLC26A3 SLC26A7

1.89e-049332M27344
PathwayREACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS

SLC26A3 SLC26A7

1.89e-049332MM15084
Pubmed

Characterization of large-scale genomic differences in the first complete human genome.

KLRC2 KLRC3

1.56e-06244237403156
Pubmed

Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.

KLRC2 KLRC3

9.37e-0644428943374
Pubmed

The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex.

KLRC2 KLRC3

1.56e-0554429683661
Pubmed

Development and function of CD94-deficient natural killer cells.

KLRC2 KLRC3

1.56e-05544221151939
Pubmed

Conservation and variation in human and common chimpanzee CD94 and NKG2 genes.

KLRC2 KLRC3

2.34e-05644211751968
Pubmed

Structural basis for NKG2A/CD94 recognition of HLA-E.

KLRC2 KLRC3

2.34e-05644218448674
Pubmed

Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9.

SLC26A3 SLC26A7

2.34e-05644211834742
Pubmed

Sequence analysis of a 62-kb region overlapping the human KLRC cluster of genes.

KLRC2 KLRC3

3.27e-0574429598306
Pubmed

Viral infection modulates Qa-1b in infected and bystander cells to properly direct NK cell killing.

KLRC2 KLRC3

4.36e-05844233765134
Pubmed

Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells.

KLRC2 KLRC3

4.36e-05844210601355
Pubmed

Physiological roles and regulation of mammalian sulfate transporters.

SLC26A3 SLC26A7

5.60e-05944211581495
Pubmed

Placental, renal, and ileal sulfate transporter gene expression in mouse gestation.

SLC26A3 SLC26A7

5.60e-05944222674389
Pubmed

Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I.

KLRC2 KLRC3

5.60e-05944214707119
Pubmed

N-glycosylation and topology of the human SLC26 family of anion transport membrane proteins.

SLC26A3 SLC26A7

6.99e-051044224647542
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

CYP1A2 SLC22A6 ABCA5 SLCO2B1

1.05e-0419344419343046
Pubmed

Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes.

DOCK10 UTP14C

1.21e-041344211700028
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DOCK10 NCAPD3 GIGYF1 MOGS WASHC5 AQR

1.61e-0465044638777146
Pubmed

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.

SLC22A6 SLCO2B1

1.86e-041644235307651
Pubmed

Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.

VPS37A SYNE1

2.10e-041744217903302
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

IPO13 NCAPD3 INTS2 ABCA5 WASHC5

5.32e-0452944514621295
Pubmed

Genetic variation in metabolizing enzyme and transporter genes: comprehensive assessment in 3 major East Asian subpopulations with comparison to Caucasians and Africans.

CYP1A2 SLCO2B1

5.38e-042744220173083
Pubmed

Defining the membrane proteome of NK cells.

DOCK10 PEX2 GEMIN5 NCAPD3 MOGS INTS2 AQR

6.12e-04116844719946888
Pubmed

Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development.

SLFN12L MTMR7

1.13e-033944238226173
Cytoband8p22

MTMR7 VPS37A

6.84e-04404428p22
CytobandEnsembl 112 genes in cytogenetic band chr8p22

MTMR7 VPS37A

9.44e-0447442chr8p22
Cytoband12p13

KLRC2 KLRC3

1.74e-036444212p13
GeneFamilySolute carriers

SLC22A6 SLC36A3 SLC26A3 SLC26A7 SLCO2B1 SLC25A51

8.39e-05395346752
GeneFamilyCD molecules|C-type lectin domain family|Killer cell lectin like receptors

KLRC2 KLRC3

2.24e-0412342621
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

KLRC2 KLRC3

2.69e-03413421298
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK10 SLFN12L KLRC2 KLRC3 SYNE1

1.18e-06189445b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 KLRC2 KLRC3 CHRNE

1.74e-05157444ad8c6eb34f5288288c4066119c17325afefbaafc
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm_gut_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SLFN12L NABP1 KLRC2 KLRC3

2.21e-0516744469de7d7fc69d699eab03dfea84fdb54263aa5a47
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 SLFN12L KLRC2 KLRC3

2.32e-051694448caf7996796a2e2716e3855de855c903d6126bf2
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 KLRC2 KLRC3 CHRNE

2.37e-0517044465c7ed586e7615203a59999549892ed466a89502
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLFN12L KLRC2 KLRC3 SYNE1

2.43e-05171444adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-mature_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SLFN12L KLRC2 KLRC3 SYNE1

2.78e-051774440f2616a81f8fbede77c860b2126e3fa826672da3
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SLFN12L KLRC2 KLRC3 SYNE1

3.17e-0518344479defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCelldroplet-Lung-nan-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 MTMR7 NABP1 SLCO2B1

3.23e-051844443261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

DOCK10 SLFN12L KLRC2 KLRC3

3.30e-05185444755c0998c729f462399f1d5e88adf4bfae31be30
ToppCellMild-Lymphoid-T-NK|Mild / Condition, Lineage, Cell class and cell subclass

SLFN12L KLRC2 KLRC3 SYNE1

3.37e-05186444ed37a2df547661d22c1ed0b30cb1c19e489d9d0a
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLFN12L KLRC2 KLRC3 SYNE1

3.37e-05186444165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCellmild_COVID-19_(asymptomatic)-gd_T|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SLFN12L KLRC2 KLRC3 SYNE1

3.37e-051864445fa3ed834898aa06aae15a8ade7ab93a6e4744f8
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 MTMR7 NABP1 SLCO2B1

3.44e-05187444f20e7a1751694390f535ffb27b97e887220f8695
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 MTMR7 NABP1 SLCO2B1

3.44e-05187444f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

SCTR SLC26A3 NEK10 AK3

3.44e-051874442ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLFN12L KLRC2 KLRC3 SYNE1

3.67e-051904441f890be1ac8613a098b271945f25a58c3c2530ab
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 SLFN12L KLRC3 SYNE1

3.67e-05190444d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLFN12L KLRC2 KLRC3 SYNE1

3.67e-05190444d7cecf88451f736f8f3f6f4644504cf22846cd6e
ToppCellPSB-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK10 SLFN12L KLRC2 KLRC3

3.67e-05190444e1b5d76edd4c1b95c0a7b94284a65043ab895e67
ToppCellNS-control-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK10 SLFN12L KLRC2 KLRC3

3.74e-0519144427f2151da2f41015a979499f274ab1284a36189f
ToppCellcontrol-Lymphoid-CTL|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DOCK10 SLFN12L KLRC2 KLRC3

3.74e-051914448df23473e24cfa51c09986102ddd391ed0f0b9cc
ToppCellcritical-Lymphoid-CTL|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DOCK10 SLFN12L KLRC2 KLRC3

3.82e-051924448c83050c1578d43ca0398ff920f30ea63f092a83
ToppCellNS-critical-d_07-13-Lymphoid-CTL|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK10 SLFN12L KLRC2 KLRC3

3.82e-05192444e7e5ba94ee8fd3c04bb4c358c86d0227c563e9dc
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLFN12L KLRC2 KLRC3 SYNE1

3.90e-051934446e1498153a7766c03fddbda1701dbf1596d21736
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 SLFN12L KLRC2 KLRC3

3.90e-05193444544de0988510cc57744710d7cafe07aa27a0b99d
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

3.90e-0519344454604c2c5dce2ff6f3ec7ca82b595b09b8cdafe8
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLFN12L KLRC2 KLRC3 SYNE1

3.90e-05193444a594f89a18273797506287d9e22f72abe53e4920
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLFN12L KLRC2 KLRC3 SYNE1

3.90e-05193444fce4f805e53669acb4c188f87ac7d84408c0c218
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

3.98e-051944440fdf4d7d42d8f1f47eade2fb89ff35b188b9b51f
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-TRGV5/7_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 SLFN12L KLRC2 KLRC3

3.98e-05194444b571f5f021619df0eedda5dd6739673f41dfab61
ToppCellnormal-na-Lymphocytic_NK-NK_bright|normal / PBMC cell types (v2) per disease, treatment status, and sex

RANBP17 KLRC2 KLRC3 SYNE1

3.98e-051944448c5f716ce05c1f187de63c1b6948eb9f90ff34fe
ToppCellnormal-na-Lymphocytic_NK-NK_bright-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

RANBP17 KLRC2 KLRC3 SYNE1

3.98e-05194444dc4aeee379423827e8d291cffe4dbdf2ff6d0bbe
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 SLFN12L KLRC2 KLRC3

3.98e-05194444b5ad5f34d76efab51a1965d9173179818f412d32
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 SLFN12L KLRC2 KLRC3

3.98e-051944444b208bb429a1e3d58a9b757b05ef4df85a1e7f1e
ToppCellCOVID-19_Moderate-CD8+_T_activated|World / disease group, cell group and cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.06e-05195444070c5d3bdbd4ea54a579c01c37fb99bcf823982e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

4.14e-0519644478b28b263deaa43590b38597186222c6447ad25f
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 SLFN12L KLRC2 KLRC3

4.14e-0519644496407d51cb19d785b98c61a626b7cb167483ec4d
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-Activated_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 SLFN12L KLRC2 KLRC3

4.14e-051964447369cf8edd3a4d7f911667bfd8d33062a0c7fb69
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

4.14e-051964443e78e307c9c991c1aadc85c61d401431cf75eaec
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

4.14e-05196444f0566f2ef96584ed6d9247b149218376fb509915
ToppCellCOVID-19_Severe-NK|World / disease group, cell group and cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.14e-05196444f46ca7cc2d8407d0dcaa77c4b16a2c1f2a23734d
ToppCellInfluenza_Severe-NK|Influenza_Severe / Disease group and Cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444d0f58ee4c02573d214deb210bb7efd3d6118f267
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-051974442abe27f6722fa0dab801bca4cd19e34c1fb4173e
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-0519744448311c7d85ffabf59fd1685c31c18b3e84a145b5
ToppCellSevere_COVID-19-T/NK-NK|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444cc20162892b59e48653981f91fc9a0c27064444d
ToppCellCOVID-19_Moderate-CD8+_T_activated|COVID-19_Moderate / disease group, cell group and cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-051974444711ecb157e907758a5021248ae8b043d17672c6
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444300849a922722adcbc068593fc5cc0bef936d9cb
ToppCellbackground-NK_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DOCK10 SLFN12L SLC26A3 KLRC2

4.22e-05197444e8e1d3e557fe821efe81012e759e35e4ae33ce86
ToppCellsevere_influenza-NK|World / disease group, cell group and cell class (v2)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-051974448e86a1ee0418e153d4f0bf291006cffc6cf36f71
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLFN12L ABCA5 NEK10 SYNE1

4.22e-05197444e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellSevere-Lymphoid-NK-NK|Severe / Condition, Lineage, Cell class and cell subclass

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444d5b94f9f73e9d050245841b19b046242a32c6258
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444a44501cac24c2f4a53b413e92bd060eed6514616
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444a26dd66a6bd08b46657b3a7c41669e206a8887b3
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-0519744492f35ea602489efd29ce3a8a186d1f70d65faf40
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444a97c4a9eb89260b0b5745834ccef9d558d857f93
ToppCellCOVID-19_Severe-NK_activated|World / disease group, cell group and cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-0519744432b770e403028862f91e4727f4a8fbb6151910e4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 KLRC3 SYNE1

4.22e-05197444bc37b8919f98dc18c2200834405f06823d965d78
ToppCellHealthy_donor-NK|World / disease group, cell group and cell class (v2)

SLFN12L KLRC2 KLRC3 SYNE1

4.30e-051984444c9c40e91173836ad0df2eba635a4cb3385e80c6
ToppCellSevere-Lymphoid-NK|Severe / Condition, Lineage, Cell class and cell subclass

SLFN12L KLRC2 KLRC3 SYNE1

4.30e-0519844426b6d20527d22ce68067cdaea6b4330cb779f91b
ToppCellsevere_influenza-NK|severe_influenza / disease group, cell group and cell class (v2)

SLFN12L KLRC2 KLRC3 SYNE1

4.30e-05198444d431beb870ff5e165d98febfb27049d729e37dc8
ToppCellCOVID-19_Severe-NK|COVID-19_Severe / disease group, cell group and cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.30e-051984440cb88084eac25604ec8f9b1497fb8d2433f1971c
ToppCellHealthy/Control-NK|World / Disease group and Cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.39e-0519944487af9c38938dc2db0f9cf9f3676895d2a8b5d7e6
ToppCellHealthy/Control-NK|Healthy/Control / Disease group and Cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.39e-05199444e7fd91080fca7c31a2d48433791da3c2a4adf14d
ToppCellCOVID-19_Severe-NK_activated|COVID-19_Severe / disease group, cell group and cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.39e-05199444bda28d975f4017ec5bded1d3c72310eabc5aac07
ToppCellHealthy_donor-NK|Healthy_donor / disease group, cell group and cell class (v2)

SLFN12L KLRC2 KLRC3 SYNE1

4.39e-051994444892d85f7c8c00e5afdcea2cd7bae0074322fa52
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-NK|Influenza_Severe / Disease, condition lineage and cell class

SLFN12L KLRC2 KLRC3 SYNE1

4.48e-0520044404ac14414d550b14dc46d682e7af9dd43982211a
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLFN12L KLRC2 KLRC3 SYNE1

4.48e-05200444eda7a1d822e8663510662bc0ca34eaccc88d71ca
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK10 SLFN12L KLRC2 CHRNE

4.48e-052004441db27223e307efca97502fca40ec5e4f8eea512b
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD8|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK10 SLFN12L KLRC2 KLRC3

4.48e-05200444a99cb2ba4a12d81644d054d30e0d450ce3db2b76
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DOCK10 NABP1 CRHR2

2.99e-04132443617644597726e881cd343e57f6edb5a98473b421
ToppCell3'_v3-blood-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|blood / Manually curated celltypes from each tissue

KLRC2 KLRC3 SYNE1

3.41e-041384439f8389a34c400a6b2b9bf6cef3a71499cc945e35
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCTR CYP1A2 RDH8

4.27e-04149443a6e192bf9bcf3b219e618c465bc451f7c86f49f1
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NABP1 KLRC2 KLRC3

4.35e-041504431f83e3be3f94aefe991a3ccd292c2d11ddef858e
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NABP1 KLRC2 KLRC3

4.35e-04150443cd666db614bc1b43d71e8eb7bf38cae4d580be80
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NABP1 KLRC2 KLRC3

4.35e-04150443f6ed3e7b36014d1e429b255b0027d89865e1ac07
ToppCellfacs-GAT-Fat-3m-Lymphocytic-NK_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 KLRC2 KLRC3

4.44e-041514433d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRC2 KLRC3 CHRNE

4.61e-041534432a94092937267cd2282452dfde3d328d763d4294
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRC2 KLRC3 CHRNE

4.61e-04153443ad33c81fe6ac10e7c263d42541aae0d796923bad
ToppCelldroplet-Liver-Npc-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP17 SCTR MTMR7

4.70e-04154443d883b3e2a65e4375bea1216eb9bbc86c64ee449c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 SLCO2B1 CRHR2

4.79e-04155443cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRC2 KLRC3 CHRNE

4.79e-041554437a16df1a40c7255c24dfb9a921b62871554c7b6d
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRC2 KLRC3 CHRNE

4.79e-04155443f51a12556ca0a3416a6cf0687f908fb4e752fb2f
ToppCellfacs-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 NABP1 WASHC5

4.88e-0415644369e6e8810d1738a66c9821910f41498931cf30cc
ToppCellfacs-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 NABP1 WASHC5

4.88e-041564433f0b9e35d4da85c90759b930052e5b9c3cde9b15
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK10 ABCA5 SLC26A7

4.97e-04157443c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCTR RDH8 CHRNE

5.06e-0415844398fd640ef0bd0014b8c38b81bd5160efcf42f23c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLFN12L KLRC2 SYNE1

5.06e-041584437274f020c0ecf216da4b6689c62bc5f49c29b6f3
ToppCellLeuk-UTI-Lymphocyte-T_NK-gdT|Leuk-UTI / Disease, Lineage and Cell Type

KLRC2 KLRC3 SYNE1

5.06e-04158443c4b0af25608cee3d0d2b0193f5ff45d9dc87078b
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCTR RDH8 CHRNE

5.06e-041584434d2d69fbb880b5232d7867b4d099d0f047ca9ebe
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MTMR7 BBS12 NEK10

5.06e-041584436811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 KLRC2 KLRC3

5.16e-0415944351bdbacb79227fbee38bb8680c58cb99878df0c7
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-TRGV5/7_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BBS12 KLRC2 KLRC3

5.16e-04159443006076bac619bf14a4c98f1158ac336bd9908914
ToppCellfacs-Lung-nan-3m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 KLRC2 KLRC3

5.35e-04161443ae1cee34361dde9964581cca99a29578c3b3bd99
ToppCellIIF-Lymphocyte-T_NK-NK_CD56bright|IIF / Disease, Lineage and Cell Type

RANBP17 ADAM32 KLRC2

5.35e-04161443b1bd1074ecba4cf171d748e2f686e9a99c0f0e89
ToppCellfacs-Lung-nan-3m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 KLRC2 KLRC3

5.35e-0416144333de3e8b3238fcfc66dfbf89a913a07d464d6c35
ToppCellE18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|E18.5-samps / Age Group, Lineage, Cell class and subclass

DOCK10 NABP1 SLCO2B1

5.45e-0416244360d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCellE18.5-samps-Myeloid|E18.5-samps / Age Group, Lineage, Cell class and subclass

DOCK10 NABP1 SLCO2B1

5.45e-0416244318e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A3 MTMR7 NEK10

5.45e-04162443d712bc31840ad1523e3dbf884acbb428a8995001
Diseaseplatelet glycoprotein ib alpha chain measurement

AK3 CHRNE

9.27e-0510432EFO_0020645
Diseaseplatelet measurement

DOCK10 SLFN12L NABP1 AK3 CHRNE

9.27e-05315435EFO_0005036
Diseaseblood pressure

VPS37A SYNE1

4.70e-0422432EFO_0004325
Diseaseimmature platelet count

DOCK10 NABP1 AK3

5.01e-04106433EFO_0803544
Diseaseimmunoglobulin isotype switching measurement

KLRC2 KLRC3

1.89e-0344432EFO_0010128
Diseasepotassium measurement

CYP1A2 NEK10

1.97e-0345432EFO_0009283
Diseasedepressive disorder (biomarker_via_orthology)

CYP1A2 CRHR2

2.63e-0352432DOID:1596 (biomarker_via_orthology)
Diseaselung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma

FRY NEK10

2.63e-0352432EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575

Protein segments in the cluster

PeptideGeneStartEntry
IPANNIIQEVQKVLL

ABCA5

586

Q8WWZ7
FQNSLLQIVIPEKIQ

ADAM32

21

Q8TC27
QILEIETFIPLLLQN

AQR

1066

O60306
LQVLIQFKVNLVLVQ

BBS12

401

Q6ZW61
LIFLKFVQAVIPTIE

ATG3

291

Q9NT62
LAQTVFLFLIAQKIP

CHRNE

281

Q04844
PFVIQALIQVIAKIT

RANBP17

101

Q9H2T7
LIPQEKIVNLVNDIF

CYP1A2

301

P05177
ELLLKLLQQQQAVPV

GIGYF1

736

O75420
LIRCKNFQIIQLIIP

MTMR7

71

Q9Y216
VINLNVPFEVIKQRL

AK3

111

Q9UIJ7
PIQQILIQLHKIIYI

NEK10

1031

Q6ZWH5
AEFLIFLLPLINVQK

PEX2

201

P28328
IAQPELEKQIFAIQL

INTS2

1046

Q9H0H0
PIILVLLINFVFLFN

CRHR2

271

Q13324
ILVVALPITIIFNKF

KCNS1

446

Q96KK3
TQDPLRQKIVFVIFL

OR4C11

16

Q6IEV9
IQLLQFNIFISLVEP

RDH8

171

Q9NYR8
QGQFLIQQVTLKIPI

MOGS

316

Q13724
FLPIILNQLFKVLVQ

DOCK10

901

Q96BY6
FFIQTLDPKLILQAV

C1orf112

636

Q9NSG2
DLFQKILVPIQQVLK

HSPA13

376

P48723
FPILIQNILNLEQDK

ETFBKMT

166

Q8IXQ9
PLNIFVKIIQFIAQE

FRY

451

Q5TBA9
FQQIQVTLVVLPLLL

SLC22A6

16

Q4U2R8
PVVVVLQQVFQLIQK

IPO13

676

O94829
PGLKNLNVVFIVLEI

NABP1

16

Q96AH0
IILQKLANVFEQPVA

SYNE1

6506

Q8NF91
TVLKTIVLIPFLEQN

KLRC2

86

P26717
AITFPIQKVLFRQQL

SLC25A51

46

Q9H1U9
VFKQQEPIQILLIFL

SCYL2

416

Q6P3W7
TVLKTIVLIPFLEQN

KLRC3

86

Q07444
VLVSQLKFIFQLTVP

SLC26A3

221

P40879
DPQVLDNFLQVLIKV

PDK3

101

Q15120
ILPFLILLVFIQNLK

SLC36A3

196

Q495N2
ILLVFIQNLKVLSVF

SLC36A3

201

Q495N2
QVQKRNFIENIIPII

NCAPD3

1191

P42695
NFIENIIPIIISLKT

NCAPD3

1196

P42695
LQKTPVIQLVLFIIQ

TMEM138

31

Q9NPI0
IILKNQQAEQLVFPL

UTP14C

146

Q5TAP6
IVNFLFLIAQLPKLQ

WASHC5

1041

Q12768
LSNILPKENQIFLFV

SLFN12L

556

Q6IEE8
QIAPNLTVIQFIKVF

SLCO2B1

346

O94956
PVILSILINFILFIN

SCTR

301

P47872
EIFQIPNLKLICTIQ

GEMIN5

561

Q8TEQ6
QVKIISINNPLVFLN

SLC26A7

501

Q8TE54
VLLEQFLTLPQLKQI

VPS37A

251

Q8NEZ2