Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium channel activity	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	2.80e-07	129	42	6	GO:0005262
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	7.09e-07	151	42	6	GO:0015085
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNA1D CACNA1S	3.10e-06	14	42	3	GO:0008331
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	4.79e-06	465	42	8	GO:0046873
GeneOntologyMolecularFunction	chemokine (C-C motif) ligand 5 binding	CCR2 CCR5	1.29e-05	3	42	2	GO:0071791
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	4.15e-05	627	42	8	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	6.22e-05	664	42	8	GO:0008324
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	7.66e-05	343	42	6	GO:0005261
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1A CACNA1D CACNA1S	1.23e-04	46	42	3	GO:0005245
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1A CACNA1D	1.54e-04	9	42	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1A CACNA1D	1.54e-04	9	42	2	GO:0099626
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	1.56e-04	758	42	8	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	2.12e-04	793	42	8	GO:0015075
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	3.71e-04	459	42	6	GO:0005216
GeneOntologyMolecularFunction	membrane insertase activity	EMC10 OXA1L	5.76e-04	17	42	2	GO:0032977
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S TRPM7 ABCA12	6.46e-04	1180	42	9	GO:0022857
GeneOntologyMolecularFunction	channel activity	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	7.54e-04	525	42	6	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S TRPM7	7.61e-04	526	42	6	GO:0022803
GeneOntologyMolecularFunction	C-C chemokine receptor activity	CCR2 CCR5	1.06e-03	23	42	2	GO:0016493
GeneOntologyMolecularFunction	C-C chemokine binding	CCR2 CCR5	1.16e-03	24	42	2	GO:0019957
GeneOntologyMolecularFunction	transporter activity	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S TRPM7 ABCA12	1.21e-03	1289	42	9	GO:0005215
GeneOntologyMolecularFunction	chemokine receptor activity	CCR2 CCR5	1.36e-03	26	42	2	GO:0004950
GeneOntologyMolecularFunction	G protein-coupled chemoattractant receptor activity	CCR2 CCR5	1.36e-03	26	42	2	GO:0001637
GeneOntologyMolecularFunction	chemokine binding	CCR2 CCR5	2.19e-03	33	42	2	GO:0019956
GeneOntologyMolecularFunction	G protein-coupled receptor activity	CCR2 OR2T1 ADORA3 GPR52 CCR5 GPR160 NPSR1	2.26e-03	884	42	7	GO:0004930
GeneOntologyMolecularFunction	protein carrier chaperone	EMC10 OXA1L	2.89e-03	38	42	2	GO:0140597
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1A CACNA1D CACNA1S	3.99e-03	152	42	3	GO:0022843
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1A CACNA1D CACNA1S	6.59e-03	182	42	3	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1A CACNA1D CACNA1S	6.79e-03	184	42	3	GO:0022832
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	1.28e-06	392	43	8	GO:0070588
GeneOntologyBiologicalProcess	endoplasmic reticulum organization	CACNA1S EMC10 REEP4 ATL2 REEP5	2.81e-06	107	43	5	GO:0007029
GeneOntologyBiologicalProcess	calcium ion transport	TRPM6 CACNA1A GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	8.83e-06	509	43	8	GO:0006816
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC6A5 TRPM6 SLC17A4 CACNA1A CCR2 GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	1.27e-05	1115	43	11	GO:0034220
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	1.51e-05	922	43	10	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	1.82e-05	942	43	10	GO:0098655
GeneOntologyBiologicalProcess	metal ion transport	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	3.05e-05	1000	43	10	GO:0030001
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	3.52e-05	1017	43	10	GO:0098660
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	CACNA1A CCR2 CLN6 CACNA1D CACNA1S CCR5 TRPM7 ABCA12 NPSR1	6.06e-05	866	43	9	GO:0055082
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	CACNA1A CACNA1D CACNA1S CCR5 NPSR1	8.56e-05	217	43	5	GO:0097553
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC6A5 TRPM6 SLC17A4 CACNA1A CCR2 GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	8.71e-05	1374	43	11	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC6A5 TRPM6 SLC17A4 CACNA1A GPM6A CACNA1D CACNA1S CCR5 TRPM7 NPSR1	1.04e-04	1157	43	10	GO:0006812
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1A CACNA1D CACNA1S	1.37e-04	48	43	3	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1A CACNA1D CACNA1S	1.37e-04	48	43	3	GO:1902656
GeneOntologyBiologicalProcess	cellular homeostasis	CACNA1A CCR2 CLN6 CACNA1D CACNA1S CCR5 TRPM7 ABCA12 NPSR1	1.57e-04	981	43	9	GO:0019725
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	CACNA1A CCR2 CLN6 CACNA1S CCR5 TRPM7 NPSR1	2.47e-04	611	43	7	GO:0030003
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	CCR2 CACNA1D ADORA3	2.53e-04	59	43	3	GO:0045761
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	CACNA1A CCR2 CLN6 CACNA1S CCR5 TRPM7 NPSR1	2.75e-04	622	43	7	GO:0006873
GeneOntologyBiologicalProcess	endoplasmic reticulum membrane organization	ATL2 REEP5	3.26e-04	13	43	2	GO:0090158
GeneOntologyBiologicalProcess	regulation of cyclase activity	CCR2 CACNA1D ADORA3	4.02e-04	69	43	3	GO:0031279
GeneOntologyBiologicalProcess	regulation of lyase activity	CCR2 CACNA1D ADORA3	4.74e-04	73	43	3	GO:0051339
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	CACNA1A CCR2 CLN6 CACNA1S CCR5 TRPM7 NPSR1	5.83e-04	705	43	7	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	CACNA1A CCR2 CLN6 CACNA1S CCR5 TRPM7 NPSR1	6.45e-04	717	43	7	GO:0050801
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	CACNA1A CCR2 CACNA1S CCR5 NPSR1	8.69e-04	359	43	5	GO:0006874
GeneOntologyBiologicalProcess	chemical homeostasis	CACNA1A CCR2 CLN6 CACNA1D CACNA1S CCR5 TRPM7 ABCA12 NPSR1	9.23e-04	1249	43	9	GO:0048878
GeneOntologyBiologicalProcess	endoplasmic reticulum tubular network organization	REEP4 ATL2	9.55e-04	22	43	2	GO:0071786
GeneOntologyCellularComponent	presynaptic membrane	SLC6A5 CACNA1A GPM6A CACNA1D ADORA3 CDH9	2.07e-05	277	43	6	GO:0042734
GeneOntologyCellularComponent	primary dendrite	CCR2 CACNA1D	2.47e-05	4	43	2	GO:0150001
GeneOntologyCellularComponent	endoplasmic reticulum tubular network	REEP4 ATL2 REEP5	3.50e-05	31	43	3	GO:0071782
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1A CACNA1D CACNA1S	1.16e-04	46	43	3	GO:0005891
GeneOntologyCellularComponent	Golgi trans cisterna	YIPF2 YIPF6	2.25e-04	11	43	2	GO:0000138
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA1D CACNA1S	2.69e-04	12	43	2	GO:1990454
GeneOntologyCellularComponent	dendrite	CACNA1A CCR2 GPM6A CACNA1D CACNA1S ADORA3 WLS CDH9	3.15e-04	858	43	8	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNA1A CCR2 GPM6A CACNA1D CACNA1S ADORA3 WLS CDH9	3.20e-04	860	43	8	GO:0097447
GeneOntologyCellularComponent	calcium channel complex	CACNA1A CACNA1D CACNA1S	4.56e-04	73	43	3	GO:0034704
GeneOntologyCellularComponent	presynaptic active zone membrane	CACNA1A GPM6A CACNA1D	5.54e-04	78	43	3	GO:0048787
GeneOntologyCellularComponent	somatodendritic compartment	CACNA1A CCR2 GPM6A CACNA1D CACNA1S ADORA3 WLS TRPM7 CDH9	7.43e-04	1228	43	9	GO:0036477
GeneOntologyCellularComponent	Golgi medial cisterna	YIPF2 YIPF6	1.02e-03	23	43	2	GO:0005797
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CLN6 EMC10 REEP4 ATL2 REEP5 WLS FADS2B FMN1 EBP	1.07e-03	1293	43	9	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CLN6 EMC10 REEP4 ATL2 REEP5 WLS FADS2B FMN1 EBP	1.11e-03	1299	43	9	GO:0098827
GeneOntologyCellularComponent	synaptic membrane	SLC6A5 CACNA1A GPM6A CACNA1D ADORA3 CDH9	1.16e-03	583	43	6	GO:0097060
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CLN6 EMC10 REEP4 ATL2 REEP5 WLS FADS2B FMN1 EBP	1.29e-03	1327	43	9	GO:0042175
GeneOntologyCellularComponent	presynapse	SLC6A5 CACNA1A GPM6A CACNA1D ADORA3 TRPM7 CDH9	2.04e-03	886	43	7	GO:0098793
GeneOntologyCellularComponent	presynaptic active zone	CACNA1A GPM6A CACNA1D	3.04e-03	141	43	3	GO:0048786
GeneOntologyCellularComponent	dendrite membrane	CACNA1D WLS	5.93e-03	56	43	2	GO:0032590
Domain	Ca_chan_IQ	CACNA1A CACNA1D CACNA1S	3.42e-07	7	41	3	PF08763
Domain	GPHH	CACNA1A CACNA1D CACNA1S	3.42e-07	7	41	3	PF16905
Domain	GPHH_dom	CACNA1A CACNA1D CACNA1S	3.42e-07	7	41	3	IPR031649
Domain	VDCC_a1su_IQ	CACNA1A CACNA1D CACNA1S	3.42e-07	7	41	3	IPR014873
Domain	Ca_chan_IQ	CACNA1A CACNA1D CACNA1S	3.42e-07	7	41	3	SM01062
Domain	VDCCAlpha1	CACNA1A CACNA1D CACNA1S	1.17e-06	10	41	3	IPR002077
Domain	Chemokine_CCR5	CCR2 CCR5	4.70e-06	2	41	2	IPR002240
Domain	Ion_trans_dom	TRPM6 CACNA1A CACNA1D CACNA1S TRPM7	4.88e-06	114	41	5	IPR005821
Domain	Ion_trans	TRPM6 CACNA1A CACNA1D CACNA1S TRPM7	4.88e-06	114	41	5	PF00520
Domain	TRPM_tetra	TRPM6 TRPM7	2.81e-05	4	41	2	PF16519
Domain	TRPM_tetra	TRPM6 TRPM7	2.81e-05	4	41	2	IPR032415
Domain	VDCC_L_a1su	CACNA1D CACNA1S	2.81e-05	4	41	2	IPR005446
Domain	MHCK_EF2_kinase	TRPM6 TRPM7	7.01e-05	6	41	2	IPR004166
Domain	Alpha_kinase	TRPM6 TRPM7	7.01e-05	6	41	2	PF02816
Domain	TB2_DP1_HVA22	REEP4 REEP5	7.01e-05	6	41	2	IPR004345
Domain	ALPHA_KINASE	TRPM6 TRPM7	7.01e-05	6	41	2	PS51158
Domain	Alpha_kinase	TRPM6 TRPM7	7.01e-05	6	41	2	SM00811
Domain	TB2_DP1_HVA22	REEP4 REEP5	7.01e-05	6	41	2	PF03134
Domain	Yip1	YIPF2 YIPF6	9.81e-05	7	41	2	PF04893
Domain	Yip1	YIPF2 YIPF6	9.81e-05	7	41	2	IPR006977
Domain	Channel_four-helix_dom	CACNA1A CACNA1D CACNA1S	2.65e-04	57	41	3	IPR027359
Domain	-	CACNA1A CACNA1D CACNA1S	2.65e-04	57	41	3	1.20.120.350
Domain	Chemokine_rcpt	CCR2 CCR5	5.53e-04	16	41	2	IPR000355
Domain	GPCR_Rhodpsn_7TM	CCR2 OR2T1 ADORA3 GPR52 CCR5 GPR160 NPSR1	5.75e-04	670	41	7	IPR017452
Domain	G_PROTEIN_RECEP_F1_1	CCR2 OR2T1 ADORA3 GPR52 CCR5 GPR160 NPSR1	6.56e-04	685	41	7	PS00237
Domain	G_PROTEIN_RECEP_F1_2	CCR2 OR2T1 ADORA3 GPR52 CCR5 GPR160 NPSR1	6.91e-04	691	41	7	PS50262
Domain	GPCR_Rhodpsn	CCR2 OR2T1 ADORA3 GPR52 CCR5 GPR160 NPSR1	6.97e-04	692	41	7	IPR000276
Domain	7tm_1	CCR2 OR2T1 ADORA3 GPR52 CCR5 NPSR1	3.38e-03	677	41	6	PF00001
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1A CACNA1D CACNA1S	1.08e-05	23	27	3	M47666
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1A CACNA1D CACNA1S	1.40e-05	25	27	3	M47948
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1D CACNA1S	5.27e-05	6	27	2	M47762
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	CCR2 OR2T1 ADORA3 GPR52 CCR5	1.19e-04	260	27	5	M39397
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	CACNA1A CACNA1S	1.92e-04	11	27	2	M47958
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004	CACNA1D CACNA1S	3.17e-04	14	27	2	M47692
Pathway	WP_CELL_INTERACTIONS_OF_THE_PANCREATIC_CANCER_MICROENVIRONMENT	CCR2 CCR5	1.12e-03	26	27	2	M46461
Pathway	REACTOME_TRP_CHANNELS	TRPM6 TRPM7	1.29e-03	28	27	2	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPM6 TRPM7	1.29e-03	28	27	2	M27241
Pathway	WP_SELECTIVE_EXPRESSION_OF_CHEMOKINE_RECEPTORS_DURING_TCELL_POLARIZATION	CCR2 CCR5	1.39e-03	29	27	2	M39797
Pathway	BIOCARTA_NKT_PATHWAY	CCR2 CCR5	1.69e-03	32	27	2	MM1492
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1A CACNA1D CACNA1S	7.93e-07	15	43	3	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1A CACNA1D CACNA1S	7.93e-07	15	43	3	24453333
Pubmed	Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis.	CCR2 CCR5	1.49e-06	2	43	2	14533004
Pubmed	Analysis of CCR5-Delta 32 and CCR2-V64I polymorphisms in a cohort of Spanish HCV patients using real-time polymerase chain reaction and fluorescence resonance energy transfer technologies.	CCR2 CCR5	1.49e-06	2	43	2	15230854
Pubmed	The channel kinases TRPM6 and TRPM7 are functionally nonredundant.	TRPM6 TRPM7	1.49e-06	2	43	2	16150690
Pubmed	Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies.	CACNA1A FMN1	1.49e-06	2	43	2	18597946
Pubmed	TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP.	TRPM6 TRPM7	1.49e-06	2	43	2	28821869
Pubmed	Distribution of chemokine receptor CCR2 and CCR5 genotypes and their relative contribution to human immunodeficiency virus type 1 (HIV-1) seroconversion, early HIV-1 RNA concentration in plasma, and later disease progression.	CCR2 CCR5	1.49e-06	2	43	2	11752157
Pubmed	Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7.	TRPM6 TRPM7	1.49e-06	2	43	2	16636202
Pubmed	CCR5 haplotypes and mother-to-child HIV transmission in Malawi.	CCR2 CCR5	1.49e-06	2	43	2	17786209
Pubmed	Influence of CCR5 and CCR2 genetic variants in the resistance/susceptibility to HIV in serodiscordant couples from Colombia.	CCR2 CCR5	1.49e-06	2	43	2	24098976
Pubmed	CCR2 and CCR5 genotypes in HIV type 1-infected adolescents: limited contributions to variability in plasma HIV type 1 RNA concentration in the absence of antiretroviral therapy.	CCR2 CCR5	1.49e-06	2	43	2	11958683
Pubmed	CCR5 promoter human haplogroups associated with HIV-1 disease progression in Thai injection drug users.	CCR2 CCR5	1.49e-06	2	43	2	15362666
Pubmed	Recent developments in intestinal magnesium absorption.	TRPM6 TRPM7	1.49e-06	2	43	2	18301276
Pubmed	Polymorphism of CC chemokine receptors CCR2 and CCR5 in Crohn's disease.	CCR2 CCR5	1.49e-06	2	43	2	11377705
Pubmed	Structural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico study.	CCR2 CCR5	1.49e-06	2	43	2	22479344
Pubmed	The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.	TRPM6 TRPM7	1.49e-06	2	43	2	18675813
Pubmed	Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice.	CCR2 CCR5	1.49e-06	2	43	2	19517561
Pubmed	Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection.	CCR2 CCR5	1.49e-06	2	43	2	19050266
Pubmed	Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection.	CCR2 CCR5	1.49e-06	2	43	2	12556692
Pubmed	Blood pressure regulation by CCR genes.	CCR2 CCR5	1.49e-06	2	43	2	17060059
Pubmed	Polymorphism of CCR5 affecting HIV disease progression in the Japanese population.	CCR2 CCR5	1.49e-06	2	43	2	11485615
Pubmed	Association of CCR5-59029 A/G and CCR2-V64I variants with renal allograft survival.	CCR2 CCR5	1.49e-06	2	43	2	19098363
Pubmed	Chemokine receptor 2-V64I and chemokine receptor 5-Delta32 polymorphisms and clinical risk factors of delayed graft function and acute rejection in kidney transplantation.	CCR2 CCR5	1.49e-06	2	43	2	22218121
Pubmed	TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.	TRPM6 TRPM7	1.49e-06	2	43	2	24858416
Pubmed	The effect of chemokine receptor gene polymorphisms (CCR2V64I, CCR5-59029G>A and CCR5Δ32) on renal allograft survival in Pakistani transplant patients.	CCR2 CCR5	1.49e-06	2	43	2	23041556
Pubmed	Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases.	TRPM6 TRPM7	1.49e-06	2	43	2	28220887
Pubmed	Genetic variation at the CCR5/CCR2 gene cluster and risk of psoriasis and psoriatic arthritis.	CCR2 CCR5	1.49e-06	2	43	2	20153665
Pubmed	[Genetic polymorphism of human immunodeficiency virus coreceptor CCR5Delta32 and CCR2-64I alleles in Chinese Yi Ethnic group in Sichuan].	CCR2 CCR5	1.49e-06	2	43	2	15769362
Pubmed	Lack of association of CCR gene polymorphisms and left ventricular hypertrophy in essential hypertension.	CCR2 CCR5	1.49e-06	2	43	2	16196460
Pubmed	Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.	CCR2 CCR5	1.49e-06	2	43	2	27895119
Pubmed	Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women.	CCR2 CCR5	1.49e-06	2	43	2	16055130
Pubmed	Determination of the CCR2-64I/CCR5-59653T haplotype linkage disequilibrium in a sample of Polish population.	CCR2 CCR5	1.49e-06	2	43	2	12884524
Pubmed	Effects of CCR2 and CCRS polymorphisms on HIV-1 infection in Thai females.	CCR2 CCR5	1.49e-06	2	43	2	18197127
Pubmed	Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways.	CCR2 CCR5	1.49e-06	2	43	2	15213273
Pubmed	Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women.	TRPM6 TRPM7	1.49e-06	2	43	2	19149903
Pubmed	CCR5 and CCR2 gene polymorphisms in hypertensive patients.	CCR2 CCR5	1.49e-06	2	43	2	12680626
Pubmed	Genetic variations in CC chemokine receptors and hypertension.	CCR2 CCR5	1.49e-06	2	43	2	16461193
Pubmed	Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus.	CCR2 CCR5	1.49e-06	2	43	2	10854218
Pubmed	Chemokine receptor CCR2/CCR5 polymorphism in Spanish patients with systemic lupus erythematosus.	CCR2 CCR5	1.49e-06	2	43	2	12913933
Pubmed	Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis.	CCR2 CCR5	1.49e-06	2	43	2	12853745
Pubmed	Polymorphisms in CCR5 chemokine receptor gene in Japan.	CCR2 CCR5	1.49e-06	2	43	2	17845302
Pubmed	Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.	TRPM6 TRPM7	1.49e-06	2	43	2	18365021
Pubmed	CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse.	CCR2 CCR5	1.49e-06	2	43	2	19824873
Pubmed	The genetic associations and epistatic effects of the CCR5 promoter and CCR2-V64I polymorphisms on susceptibility to HIV-1 infection in a Northern Han Chinese population.	CCR2 CCR5	1.49e-06	2	43	2	23057571
Pubmed	Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine.	CCR2 CCR5	1.49e-06	2	43	2	10843684
Pubmed	Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.	TRPM6 TRPM7	1.49e-06	2	43	2	14976260
Pubmed	Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.	TRPM6 TRPM7	1.49e-06	2	43	2	18192217
Pubmed	Genetic contribution of chemokine receptor 2 (CCR2) polymorphisms towards increased serum total IgE levels in Indian asthmatics.	CCR2 CCR5	1.49e-06	2	43	2	19520154
Pubmed	Hypokalaemic periodic paralysis due to the CACNA1S R1239H mutation in a large African family.	CACNA1A CACNA1S	1.49e-06	2	43	2	17418573
Pubmed	Impact of chemokine receptor CCR2 and CCR5 gene polymorphism on allograft outcome in North Indian renal transplant recipients.	CCR2 CCR5	1.49e-06	2	43	2	19037908
Pubmed	Frequency of polymorphisms of genes coding for HIV-1 co-receptors CCR5 and CCR2 in a Brazilian population.	CCR2 CCR5	1.49e-06	2	43	2	14533983
Pubmed	CCR2 and CCR5 genes polymorphisms in women with cervical lesions from Pernambuco, Northeast Region of Brazil: a case-control study.	CCR2 CCR5	1.49e-06	2	43	2	26982176
Pubmed	Chemokine CCL5 promotes robust optic nerve regeneration and mediates many of the effects of CNTF gene therapy.	CCR2 CCR5	1.49e-06	2	43	2	33627402
Pubmed	A multiethnic study of Delta32ccr5 and ccr2b-V64I allele distribution in four Los Angeles populations.	CCR2 CCR5	1.49e-06	2	43	2	11385319
Pubmed	Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia.	TRPM6 TRPM7	1.49e-06	2	43	2	21602712
Pubmed	Distribution of CCR5-Delta 32 and CCR2-64I alleles in an Argentine Amerindian population.	CCR2 CCR5	1.49e-06	2	43	2	11696224
Pubmed	Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.	CCR2 CCR5	1.49e-06	2	43	2	12837756
Pubmed	CCR2/CCR5-mediated macrophage-smooth muscle cell crosstalk in pulmonary hypertension.	CCR2 CCR5	1.49e-06	2	43	2	31320454
Pubmed	Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin.	TRPM6 TRPM7	1.49e-06	2	43	2	26563869
Pubmed	Effect of genetic variants of chemokine receptors on the development of myocardial infarction in Turkish population.	CCR2 CCR5	1.49e-06	2	43	2	20182805
Pubmed	The frequency of CCR5Delta32 and CCR2-64I in southern Iranian normal population.	CCR2 CCR5	1.49e-06	2	43	2	15585333
Pubmed	Possible contribution of chemokine receptor CCR2 and CCR5 polymorphisms in the pathogenesis of chronic spontaneous autoreactive urticaria.	CCR2 CCR5	1.49e-06	2	43	2	23727176
Pubmed	Chemokine receptor genotype is associated with diabetic nephropathy in Japanese with type 2 diabetes.	CCR2 CCR5	1.49e-06	2	43	2	11756347
Pubmed	[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].	CACNA1D CACNA1S	1.49e-06	2	43	2	21789999
Pubmed	The Different Roles of The Channel-Kinases TRPM6 and TRPM7.	TRPM6 TRPM7	1.49e-06	2	43	2	26179995
Pubmed	Lack of association of human chemokine receptor gene polymorphisms CCR2-64I and CCR5-Delta32 with autoimmune Addison's disease.	CCR2 CCR5	1.49e-06	2	43	2	15086346
Pubmed	Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis.	TRPM6 TRPM7	1.49e-06	2	43	2	16075242
Pubmed	CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis.	CCR2 CCR5	1.49e-06	2	43	2	34747459
Pubmed	Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy.	CCR2 CCR5	1.49e-06	2	43	2	16316965
Pubmed	Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.	CACNA1D CACNA1S	1.49e-06	2	43	2	28978442
Pubmed	Evidence for the expression of TRPM6 and TRPM7 in cardiomyocytes from all four chamber walls of the human heart.	TRPM6 TRPM7	1.49e-06	2	43	2	34326388
Pubmed	Genetic polymorphism of chemokine receptors CCR2 and CCR5 in Swedish cervical cancer patients.	CCR2 CCR5	1.49e-06	2	43	2	17094383
Pubmed	Protection from pulmonary fibrosis in the absence of CCR2 signaling.	CCR2 CCR5	1.49e-06	2	43	2	11591761
Pubmed	Analysis of the involvement of CCR5-Delta32 and CCR2-V64I variants in the development of endometriosis.	CCR2 CCR5	1.49e-06	2	43	2	14981141
Pubmed	Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis.	CCR2 CCR5	1.49e-06	2	43	2	15067318
Pubmed	Effects of polymorphisms of chemokine receptors on neurodevelopment and the onset of encephalopathy in children with perinatal HIV-1 infection.	CCR2 CCR5	1.49e-06	2	43	2	17361671
Pubmed	Genetic diversity and linkage disequilibrium in the chemokine receptor CCR2-CCR5 region among individuals and populations.	CCR2 CCR5	1.49e-06	2	43	2	24011637
Pubmed	Differential mRNA expression and glucocorticoid-mediated regulation of TRPM6 and TRPM7 in the heart and kidney throughout murine pregnancy and development.	TRPM6 TRPM7	1.49e-06	2	43	2	25692682
Pubmed	TRPM6 is Essential for Magnesium Uptake and Epithelial Cell Function in the Colon.	TRPM6 TRPM7	1.49e-06	2	43	2	29912157
Pubmed	Magnesium and its transporters in cancer: a novel paradigm in tumour development.	TRPM6 TRPM7	1.49e-06	2	43	2	22671428
Pubmed	Genetic variation at the chemokine receptors CCR5/CCR2 in myocardial infarction.	CCR2 CCR5	1.49e-06	2	43	2	11477473
Pubmed	The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels.	TRPM6 TRPM7	1.49e-06	2	43	2	24385424
Pubmed	Combined effect of CCR5-Delta32 heterozygosity and the CCR5 promoter polymorphism -2459 A/G on CCR5 expression and resistance to human immunodeficiency virus type 1 transmission.	CCR2 CCR5	1.49e-06	2	43	2	16140745
Pubmed	Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians.	CCR2 CCR5	1.49e-06	2	43	2	21429204
Pubmed	Dominant effects of CCR2-CCR5 haplotypes in HIV-1 disease progression.	CCR2 CCR5	1.49e-06	2	43	2	15602133
Pubmed	Adverse effect of the CCR5 promoter -2459A allele on HIV-1 disease progression.	CCR2 CCR5	1.49e-06	2	43	2	11596075
Pubmed	CC chemokine receptor 5 delta32 and CC chemokine receptor 2 64I polymorphisms do not influence the virologic and immunologic response to antiretroviral combination therapy in human immunodeficiency virus type 1-infected patients.	CCR2 CCR5	1.49e-06	2	43	2	12447757
Pubmed	Association study between CCR2-CCR5 genes polymorphisms and chronic Chagas heart disease in Wichi and in admixed populations from Argentina.	CCR2 CCR5	1.49e-06	2	43	2	30650073
Pubmed	C-C chemokine receptor 2 and C-C chemokine receptor 5 genotypes in patients treated for chronic hepatitis C virus infection.	CCR2 CCR5	1.49e-06	2	43	2	12403355
Pubmed	CCR2 and CCR5 genes polymorphisms in benign prostatic hyperplasia and prostate cancer.	CCR2 CCR5	1.49e-06	2	43	2	23632061
Pubmed	SNP/haplotype associations of CCR2 and CCR5 genes with severity of chagasic cardiomyopathy.	CCR2 CCR5	1.49e-06	2	43	2	25312802
Pubmed	Gene variation of the transient receptor potential cation channel, subfamily M, members 6 (TRPM6) and 7 (TRPM7), and type 2 diabetes mellitus: a case-control study.	TRPM6 TRPM7	1.49e-06	2	43	2	20875900
Pubmed	Heterozygosity for CCR5-Delta32 but not CCR2b-64I protects against certain intracellular pathogens.	CCR2 CCR5	1.49e-06	2	43	2	12010355
Pubmed	Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of myocardial infarction among Tunisian male patients.	CCR2 CCR5	1.49e-06	2	43	2	22285384
Pubmed	Chemokine receptor genotype and response to interleukin-2 therapy in HIV-1-infected individuals.	CCR2 CCR5	1.49e-06	2	43	2	12584049
Pubmed	Analysis of CC chemokine receptor 5 and 2 polymorphisms and renal transplant survival.	CCR2 CCR5	1.49e-06	2	43	2	16598837
Pubmed	ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.	EMC10 REEP4 ATL2 REEP5 TRPM7 TM9SF3	1.79e-06	299	43	6	37931956
Pubmed	CCR2-64I allele is associated with the progression of AIDS in a Han Chinese population.	CCR2 CCR5	4.48e-06	3	43	2	19669591
Pubmed	Chemokine and chemokine receptor gene polymorphism in Tunisian hemodialysis patients with HCV infection.	CCR2 CCR5	4.48e-06	3	43	2	22026334
Interaction	YIPF6 interactions	YIPF2 REEP4 LRRC3B MMD YIPF6 EBP	1.28e-07	117	41	6	int:YIPF6
Interaction	VIPR1 interactions	TRPM6 CLN6 OXA1L REEP5 WLS YIPF6 EBP	1.71e-07	205	41	7	int:VIPR1
Interaction	TCTN3 interactions	CACNA1A EMC10 REEP4 REEP5 WLS TRPM7 TM9SF3 EBP	3.11e-07	334	41	8	int:TCTN3
Interaction	GPR52 interactions	GPR52 EMC10 REEP5 EBP	7.37e-07	35	41	4	int:GPR52
Interaction	YIPF3 interactions	SLC6A5 GPM6A GPR52 REEP4 MFSD11 TM9SF3	1.96e-06	186	41	6	int:YIPF3
Interaction	CCR2 interactions	CCR2 EMC10 CCR5 WLS	4.02e-06	53	41	4	int:CCR2
Interaction	EMC6 interactions	EMC10 REEP5 MMD EBP	1.16e-05	69	41	4	int:EMC6
Interaction	TMEM60 interactions	REEP4 LRRC3B MMD EBP	3.62e-05	92	41	4	int:TMEM60
Interaction	TVP23B interactions	YIPF2 REEP4 YIPF6	3.72e-05	32	41	3	int:TVP23B
Interaction	ARL6IP5 interactions	SLC6A5 CCR2 CCR5 ATL2 REEP5	4.23e-05	192	41	5	int:ARL6IP5
Interaction	CGRRF1 interactions	CLN6 EMC10 WLS YIPF6	5.63e-05	103	41	4	int:CGRRF1
Interaction	CYP4F2 interactions	REEP4 MMD EBP	6.27e-05	38	41	3	int:CYP4F2
Interaction	LPAR1 interactions	OXA1L REEP4 REEP5 YIPF6 TM9SF3	6.47e-05	210	41	5	int:LPAR1
Interaction	SLC6A5 interactions	SLC6A5 OXA1L ATL2	6.79e-05	39	41	3	int:SLC6A5
Interaction	TMEM167B interactions	REEP4 REEP5 EBP	7.33e-05	40	41	3	int:TMEM167B
Interaction	RETREG3 interactions	SLC6A5 REEP4 REEP5 YIPF6 SFT2D1	8.41e-05	222	41	5	int:RETREG3
Interaction	FFAR1 interactions	CLN6 OXA1L WLS YIPF6 EBP	1.10e-04	235	41	5	int:FFAR1
Interaction	TRPM6 interactions	TRPM6 TRPM7	1.12e-04	8	41	2	int:TRPM6
Interaction	DERL2 interactions	SLC6A5 GPM6A REEP5 SFT2D1	1.16e-04	124	41	4	int:DERL2
Interaction	HSD17B11 interactions	REEP4 ATL2 REEP5 TRPM7 YIPF6 EBP	1.28e-04	390	41	6	int:HSD17B11
Interaction	EDNRA interactions	OXA1L REEP4 EBP	1.71e-04	53	41	3	int:EDNRA
Interaction	FPR2 interactions	OXA1L REEP4 ATL2 REEP5	1.75e-04	138	41	4	int:FPR2
Interaction	TMEM208 interactions	REEP4 REEP5 EBP	1.80e-04	54	41	3	int:TMEM208
Interaction	TMEM199 interactions	CCR2 REEP4 REEP5 EBP	1.85e-04	140	41	4	int:TMEM199
Interaction	EMC10 interactions	CCR2 GPR52 EMC10	1.91e-04	55	41	3	int:EMC10
Interaction	SCN10A interactions	CACNA1A CACNA1D	2.20e-04	11	41	2	int:SCN10A
Interaction	ESYT1 interactions	EMC10 REEP4 ATL2 REEP5 TRPM7 TM9SF3	2.20e-04	431	41	6	int:ESYT1
Interaction	TMEM42 interactions	REEP4 MMD EBP	2.23e-04	58	41	3	int:TMEM42
Interaction	TMEM14B interactions	YIPF2 REEP4 YIPF6 EBP SFT2D1	2.45e-04	279	41	5	int:TMEM14B
Interaction	EMP1 interactions	CCR5 LRRC3B EBP	3.13e-04	65	41	3	int:EMP1
Interaction	YIPF4 interactions	GPR52 REEP4 EBP	3.57e-04	68	41	3	int:YIPF4
Interaction	NALCN interactions	CACNA1A CACNA1D	3.62e-04	14	41	2	int:NALCN
Interaction	CCL16 interactions	CCR2 CCR5	3.62e-04	14	41	2	int:CCL16
Interaction	SLC30A8 interactions	REEP4 YIPF6 SFT2D1	4.06e-04	71	41	3	int:SLC30A8
Interaction	SCN11A interactions	CACNA1A CACNA1D	4.17e-04	15	41	2	int:SCN11A
Interaction	LRRC3B interactions	LRRC3B YIPF6	4.76e-04	16	41	2	int:LRRC3B
Interaction	LEMD1 interactions	REEP4 EBP	4.76e-04	16	41	2	int:LEMD1
Interaction	TEX2 interactions	REEP4 ATL2 REEP5 TM9SF3	5.56e-04	187	41	4	int:TEX2
Interaction	REEP4 interactions	REEP4 REEP5 YIPF6 SFT2D1	6.26e-04	193	41	4	int:REEP4
Interaction	STX1A interactions	SLC6A5 CLN6 GPM6A CACNA1D	7.29e-04	201	41	4	int:STX1A
Interaction	RTP2 interactions	REEP4 REEP5 EBP	7.86e-04	89	41	3	int:RTP2
Interaction	CACFD1 interactions	REEP5 TM9SF3	8.27e-04	21	41	2	int:CACFD1
Interaction	SCN9A interactions	CACNA1A CACNA1D	8.27e-04	21	41	2	int:SCN9A
Interaction	ARLN interactions	REEP4 MMD EBP	8.39e-04	91	41	3	int:ARLN
Interaction	REEP5 interactions	GPR52 REEP4 ATL2 REEP5 EBP	8.95e-04	371	41	5	int:REEP5
Interaction	CCL8 interactions	CCR2 CCR5	9.09e-04	22	41	2	int:CCL8
Interaction	CCL7 interactions	CCR2 CCR5	9.09e-04	22	41	2	int:CCL7
Interaction	CACNB2 interactions	CACNA1A CACNA1D	9.94e-04	23	41	2	int:CACNB2
Interaction	ODR4 interactions	GPM6A REEP5 LRRC3B	1.07e-03	99	41	3	int:ODR4
Interaction	VKORC1L1 interactions	SLC6A5 GPM6A GPR52	1.07e-03	99	41	3	int:VKORC1L1
Interaction	CACNA1D interactions	CACNA1A CACNA1D	1.08e-03	24	41	2	int:CACNA1D
Interaction	CMKLR1 interactions	OXA1L ATL2 TM9SF3	1.13e-03	101	41	3	int:CMKLR1
Interaction	MMD interactions	MMD YIPF6	1.18e-03	25	41	2	int:MMD
Interaction	ATL2 interactions	SLC6A5 ATL2 REEP5	1.23e-03	104	41	3	int:ATL2
Interaction	TMX2 interactions	YIPF2 REEP4 YIPF6 SFT2D1	1.26e-03	233	41	4	int:TMX2
Interaction	TMEM11 interactions	ADORA3 YIPF6 EBP	1.27e-03	105	41	3	int:TMEM11
Interaction	TPST1 interactions	CCR2 CCR5	1.27e-03	26	41	2	int:TPST1
Interaction	FRMD3 interactions	OXA1L REEP4	1.27e-03	26	41	2	int:FRMD3
Interaction	OTULINL interactions	EMC10 REEP4 REEP5 TRPM7 EBP	1.32e-03	405	41	5	int:OTULINL
Interaction	ODF4 interactions	YIPF6 EBP	1.37e-03	27	41	2	int:ODF4
Interaction	HTR3A interactions	GPM6A WLS EBP	1.38e-03	108	41	3	int:HTR3A
Interaction	LRRC59 interactions	CLN6 REEP4 REEP5 WLS TRPM7 TM9SF3 EBP	1.44e-03	845	41	7	int:LRRC59
Interaction	PRAF2 interactions	CCR5 REEP4 REEP5	1.57e-03	113	41	3	int:PRAF2
Interaction	SCN1A interactions	CACNA1A CACNA1D	1.58e-03	29	41	2	int:SCN1A
Interaction	CCL13 interactions	CCR2 CCR5	1.58e-03	29	41	2	int:CCL13
Interaction	ATP2A1 interactions	ATL2 REEP5 WLS TRPM7 TM9SF3	1.60e-03	423	41	5	int:ATP2A1
Interaction	EBP interactions	GPR52 REEP5 YIPF6 EBP	1.61e-03	249	41	4	int:EBP
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA1D CACNA1S	8.44e-06	26	28	3	253
GeneFamily	Receptor accessory proteins	REEP4 REEP5	3.46e-05	6	28	2	717
GeneFamily	Yip1 domain containing	YIPF2 YIPF6	4.83e-05	7	28	2	105
GeneFamily	CD molecules\|C-C motif chemokine receptors	CCR2 CCR5	1.03e-04	10	28	2	1091
GeneFamily	Transient receptor potential cation channels	TRPM6 TRPM7	8.53e-04	28	28	2	249
GeneFamily	G protein-coupled receptors, Class A orphans	GPR52 GPR160	6.46e-03	78	28	2	262
GeneFamily	Solute carriers	SLC6A5 SLC17A4 SLC35F4	2.26e-02	395	28	3	752
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D TRPM7 FMN1 NPSR1	8.74e-06	135	43	4	88f86bab637f1ca1439c7de2d12be4329cf662b8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	1.54e-05	156	43	4	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	1.71e-05	160	43	4	2d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	1.71e-05	160	43	4	8bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	2.32e-05	173	43	4	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	2.32e-05	173	43	4	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	facs-Marrow-T_cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S GPR52 YIPF2 FMN1	2.32e-05	173	43	4	e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCell	facs-Marrow-T-cells-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A CACNA1S YIPF2 YIPF6	2.42e-05	175	43	4	0a01e0104cfa3091bc05b0f1d087c941688169a5
ToppCell	facs-Marrow-T-cells-24m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A CACNA1S YIPF2 YIPF6	2.65e-05	179	43	4	3f2934c5f8816a7b7a6aef8d2f83ebf7b2b693bf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	2.65e-05	179	43	4	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	2.77e-05	181	43	4	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MORC1 GPM6A ATL2 SLC35F4	2.83e-05	182	43	4	37547b36264090b49a193a8ef3a8d88e647f0b79
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 WLS TRPM7 FMN1	2.89e-05	183	43	4	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	droplet-Thymus-nan-24m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A CACNA1S YIPF2 GPR160	3.01e-05	185	43	4	e583f6601f9ed79b0b23d2f9426a4ba8b969230b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.21e-05	188	43	4	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Early_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MORC1 GPM6A TECRL FOXO6	3.21e-05	188	43	4	6151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.21e-05	188	43	4	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	TRPM6 CACNA1D TRPM7 FMN1	3.21e-05	188	43	4	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.27e-05	189	43	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.27e-05	189	43	4	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.27e-05	189	43	4	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.27e-05	189	43	4	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.34e-05	190	43	4	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.34e-05	190	43	4	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D TRPM7 FMN1	3.63e-05	194	43	4	f08a7618a9ccf12e4a7620235ae662a8abc521af
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A CACNA1S YIPF2 YIPF6	3.70e-05	195	43	4	f9a90cd7b4e99a0947fdb3645f7787d02b0f7ca0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 WLS TRPM7 FMN1	3.70e-05	195	43	4	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 CCR5 WLS TM9SF3	3.85e-05	197	43	4	173c0c8de4e69882a9f91189deeb4a651fefe551
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 CCR5 WLS TM9SF3	3.85e-05	197	43	4	e73ca8c8f42cbcc56eaa5fe3d69abd1ce7b7bbca
ToppCell	facs-Brain_Myeloid-Cortex_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 CCR5 WLS TM9SF3	3.85e-05	197	43	4	81379fe6bd14a1ba26f4a159497262adcb600b18
ToppCell	facs-Brain_Myeloid-Cortex_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 CCR5 WLS TM9SF3	3.85e-05	197	43	4	271c75f491d03bd248c7ec037ef02e39456f3ac0
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 CCR5 WLS TM9SF3	3.85e-05	197	43	4	9db329c6fea532dd1afb624f4c29c92407f45568
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CCR2 ADORA3 CCR5 FMN1	3.93e-05	198	43	4	7f7024b26337ae2bc7f57c3274a7dfdaaa64ab7c
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCR2 ADORA3 CCR5 FMN1	3.93e-05	198	43	4	59214e34b077dffa989c48635fdef143f57f1320
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_2-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCR2 ADORA3 CCR5 OXA1L	3.93e-05	198	43	4	984b3753fabd5553f6f364f90a422b035e421535
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	9.94e-05	93	43	3	d84d8fb3f2553364edf4cf5488a2747512fe65af
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	9.94e-05	93	43	3	3223e3e4e1a571bd947949ae545c49cfefe53dce
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	9.94e-05	93	43	3	b6653a0eafe0409d7582640706e729202f3b40ea
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	9.94e-05	93	43	3	78de1ca2c5a8511580fa47734df951d0ee5c518a
ToppCell	Hippocampus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	1.06e-04	95	43	3	6122a821dd1d1630ce11d219dcde6bd74e5487d1
ToppCell	Hippocampus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	1.06e-04	95	43	3	ac03599e8e16465dbede1ce5c6a4176246d79fa1
ToppCell	Hippocampus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	1.06e-04	95	43	3	d5f5af5bf542a72a4f9dba05277824b5c8b2fb6d
ToppCell	Hippocampus-Hematopoietic-MICROGLIA-MI2(C1qb)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	1.06e-04	95	43	3	8f058263d52099544488bd4ee1850d97dfd33de4
ToppCell	Hippocampus-Hematopoietic-MICROGLIA\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	1.06e-04	95	43	3	aa217fa29152df1dbc54d33f36e3f288a18ef417
ToppCell	Cerebellum-Hematopoietic-MICROGLIA\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	3.25e-04	139	43	3	75cca1e6c1af289987d5d98455e9c6db81ecdd64
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1A ABCA12 CDH9	3.25e-04	139	43	3	a1945b07f177cde40e7eea03a19236ce76165857
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	3.25e-04	139	43	3	de34e2f51f6fda638357abb662c111a20b83e70b
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	3.25e-04	139	43	3	a077ce50f6d6746d80de35abed5b6dc35b1145b9
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	3.25e-04	139	43	3	0ae117308bd10d3a7d2688794c69dc5a31cfca5f
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	3.25e-04	139	43	3	fac6a3100a277efa1db250e0c576be1a0c901e6d
ToppCell	Cerebellum-Hematopoietic\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CCR2 ADORA3 CCR5	3.25e-04	139	43	3	3913c3828ad4cb5c71380519d0cf5f195e53c51d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 CACNA1D FMN1	3.32e-04	140	43	3	5e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCR2 CCR5 MMD	3.32e-04	140	43	3	a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC17A4 CCR2 CCR5	3.61e-04	144	43	3	8bd042f12186f36bc5aabf6a0232270a448f4b58
ToppCell	10x3'2.3-week_12-13-Myeloid_DC-DC-tDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCR2 GPM6A CACNA1D	3.68e-04	145	43	3	a6c291811bf62f1c13f1b4b396d75c2223cf1c7d
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Tgfb1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GPR52 FOXO6 CDH9	3.68e-04	145	43	3	84d50a13b48d50c16e768422908e371a55972d0e
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR2 CCR5 GPR160	3.76e-04	146	43	3	26493014daa432db721613ef480d133f3da9eb58
ToppCell	COVID-19_Mild-PLT_5\|World / Disease Group and Platelet Clusters	CCR5 TECRL FMN1	4.23e-04	152	43	3	90ba4e8a735ec8921038fa072129535f0e3fd9ae
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 CCR5 GPR160	4.23e-04	152	43	3	ed6df77ba04b715e12c2e1591b4a1e894ca49d25
ToppCell	PND01-Immune-Immune_Myeloid-DC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 ADORA3 CCR5	4.23e-04	152	43	3	c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCell	E16.5-samps-Myeloid-Fetal_macrophage-Proliferative_Myeloid\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CCR2 CCR5 GPR160	4.23e-04	152	43	3	e427758a6e39052616a0d8ecec0c1299e81d1d3c
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 ADORA3 CCR5	4.23e-04	152	43	3	c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 ADORA3 CCR5	4.23e-04	152	43	3	cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCell	E16.5-samps-Myeloid-Fetal_macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CCR2 CCR5 GPR160	4.31e-04	153	43	3	e9567966fe4426176e2f2dc0be4832c769c9903a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 TRPM7 FMN1	4.31e-04	153	43	3	98670bbce4a770af244f033cdd2d54db57200ca8
ToppCell	Striatum-Hematopoietic\|Striatum / BrainAtlas - Mouse McCarroll V32	ADORA3 CCR5 GPR160	4.47e-04	155	43	3	12301d823338bf829475905c66c5f08f7159d29f
ToppCell	droplet-Heart-4Chambers-21m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CACNA1S ADORA3	4.56e-04	156	43	3	5d97755db872d51522f6412a93704f3c79a084cd
ToppCell	E16.5-samps-Myeloid\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CCR2 CCR5 GPR160	4.56e-04	156	43	3	c7c73cef5700b0ae75280e62c94728434c712537
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 ADORA3 CCR5	4.64e-04	157	43	3	904cd98ae85ed6459e0663f077ac462842bf12df
ToppCell	facs-Spleen-nan-18m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CCR5 GPR160	4.64e-04	157	43	3	a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S CCR5 ABCA12	4.82e-04	159	43	3	656aa20706bdba81bbcc3e68e6058215b92b8802
ToppCell	mild-Myeloid-CD14_Monocytes_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CCR2 CCR5 REEP4	4.91e-04	160	43	3	a83568cd8a0b05642bacd43a8ec443e5ce314c4d
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1S ADORA3 CCR5	5.00e-04	161	43	3	76c993a4533362db2250c88b3ee3ede55362d54e
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CACNA1S CCR5	5.00e-04	161	43	3	f5821f551cf5c64c9f75cdb723492c87aac1ece0
ToppCell	droplet-Heart-nan-24m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CACNA1S ADORA3	5.00e-04	161	43	3	7e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CACNA1S CCR5	5.00e-04	161	43	3	58a32a1033f379579697bda1bbf047a088e4a34f
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CACNA1S CCR5	5.00e-04	161	43	3	16f77e7a5444d2f2b210362816cd7a07b9b42af6
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 CCR5 ABCA12	5.09e-04	162	43	3	9d6931619f5eb847c79d00ff5ae031fef30fd55c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CCR2 YIPF2 CCR5	5.18e-04	163	43	3	ce07bc424ef99c547588b07f5c8b39ff0773ca9b
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 ADORA3 CCR5	5.18e-04	163	43	3	7af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR2 ADORA3 GPR52	5.27e-04	164	43	3	cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCR2 ADORA3 GPR52	5.27e-04	164	43	3	6d331e74efecb4733d87653f86cd67247be05025
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR5 FMN1 GPR160	5.37e-04	165	43	3	fe2135fdacf3807eb4b5ea5e790febfb8cd54335
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR5 FMN1 GPR160	5.37e-04	165	43	3	47e716ce8dc283d406352c1909e09362fcb9e3a3
ToppCell	droplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 ADORA3 CCR5	5.46e-04	166	43	3	e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPM6A CACNA1S YIPF2	5.56e-04	167	43	3	8ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPM6A CACNA1S YIPF2	5.56e-04	167	43	3	a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GPR52 FOXO6 CDH9	5.66e-04	168	43	3	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TRPM6 GPM6A LRRC3B	5.66e-04	168	43	3	5ce3129a023a48a3d7e6b9306c1fc5addfef9675
ToppCell	facs-Large_Intestine-Proximal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A4 ABCA12 MMD	5.66e-04	168	43	3	23e0e1592d7400012d289adb10c7598285bae2e9
ToppCell	droplet-Pancreas-PANCREAS-30m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CACNA1S CCR5	5.66e-04	168	43	3	5946204d42307391bc2160abe12850815f350aea
ToppCell	droplet-Bladder-nan-24m-Hematologic-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR2 CACNA1S CCR5	5.66e-04	168	43	3	c6e0daa790dd5db20dd1ab8c1e7142484976d743
ToppCell	facs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A CACNA1S YIPF6	5.75e-04	169	43	3	b798b91567d2f49082e2d8a337169f241c8d2080
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 CDH9 TMEM145	5.75e-04	169	43	3	bca5322880c09b78ef10d9dda6420a80c1ba7e62
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FOXO6 ABCA12 EBP	5.75e-04	169	43	3	aec97583b23112060437b619cb429dc32f29285f
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EMC10 TECRL FMN1	5.85e-04	170	43	3	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	EMC10 TECRL FMN1	5.85e-04	170	43	3	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GPR52 FOXO6 CDH9	5.95e-04	171	43	3	d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCell	PND14-Immune-Immune_Myeloid-DC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCR2 ADORA3 CCR5	5.95e-04	171	43	3	8772d6349db24de47f089df2032a80345db7177f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC17A4 CACNA1D GPR160	5.95e-04	171	43	3	f2b31c97bbcc5164fc279ed0362007878887ad5e
Computational	Complement and cAMP signaling.	ADORA3 MMD	1.54e-04	12	17	2	MODULE_575
Computational	Genes in the cancer module 367.	CCR2 CCR5	9.32e-04	29	17	2	MODULE_367
Computational	Genes in the cancer module 134.	CCR2 CCR5	9.98e-04	30	17	2	MODULE_134
Computational	Genes in the cancer module 288.	CCR2 CCR5	1.52e-03	37	17	2	MODULE_288
Drug	AC1L1JG6	CACNA1A CACNA1D CACNA1S	1.95e-06	14	41	3	CID000005026
Drug	Verapamil	CACNA1A CACNA1D CACNA1S	2.99e-06	16	41	3	DB00661
Drug	proanthocyanidin	CCR2 CCR5	9.48e-06	3	41	2	ctd:C013221
Drug	gamma-aminobutyric acid	SLC6A5 MORC1 CACNA1A CACNA1D CACNA1S ADORA3 EBP	1.98e-05	474	41	7	CID000000119
Drug	CNS 1145	CACNA1A CACNA1D CACNA1S	2.85e-05	33	41	3	CID000190902
Drug	IHC-64	CACNA1A CACNA1D CACNA1S	2.85e-05	33	41	3	CID000162753
Drug	Nilvadipine	CACNA1D CACNA1S	3.15e-05	5	41	2	DB06712
Drug	Nisoldipine	CACNA1D CACNA1S	3.15e-05	5	41	2	DB00401
Drug	mag-fura-2	TRPM6 CACNA1S TRPM7	4.04e-05	37	41	3	CID000123839
Drug	CPU-23	CACNA1D CACNA1S	4.72e-05	6	41	2	CID003036051
Drug	Amlodipine	CACNA1D CACNA1S	6.61e-05	7	41	2	DB00381
Drug	Isradipine	CACNA1D CACNA1S	6.61e-05	7	41	2	DB00270
Drug	h PM	CACNA1A CACNA1D CACNA1S	7.30e-05	45	41	3	CID005494424
Drug	Nitrendipine	CACNA1D CACNA1S	8.80e-05	8	41	2	DB01054
Drug	Nifedipine	CACNA1D CACNA1S	8.80e-05	8	41	2	DB01115
Drug	Barium permanganate	CACNA1A CACNA1D CACNA1S TRPM7	9.53e-05	133	41	4	CID000024587
Drug	KW-3049	CACNA1A CACNA1D CACNA1S	1.00e-04	50	41	3	CID000002324
Drug	lanthanum	CACNA1A CACNA1D CACNA1S TRPM7	1.04e-04	136	41	4	CID000023926
Drug	Cinnarizine	CACNA1D CACNA1S	1.13e-04	9	41	2	DB00568
Drug	Nimodipine	CACNA1D CACNA1S	1.13e-04	9	41	2	DB00393
Drug	Cinildipine	CACNA1A CACNA1D CACNA1S	1.41e-04	56	41	3	CID000002752
Drug	Felodipine	CACNA1D CACNA1S	1.72e-04	11	41	2	DB01023
Drug	Mibefradil	CACNA1D CACNA1S	1.72e-04	11	41	2	DB01388
Drug	3-chlorophenol	CCR2 CCR5	1.72e-04	11	41	2	ctd:C030682
Drug	nilvadipine	CACNA1A CACNA1D CACNA1S	1.73e-04	60	41	3	CID000004494
Drug	IAA-94	CACNA1A CACNA1D CACNA1S	1.81e-04	61	41	3	CID000003667
Drug	lercanidipine	CACNA1A CACNA1D CACNA1S	2.00e-04	63	41	3	CID000065866
Drug	NSC759256	CACNA1A CACNA1D CACNA1S	2.00e-04	63	41	3	CID000125889
Drug	mibefradil	CACNA1A CACNA1D CACNA1S	2.09e-04	64	41	3	CID000060662
Drug	gallopamil	CACNA1A CACNA1D CACNA1S	2.40e-04	67	41	3	CID000001234
Drug	epostane	CCR2 CCR5	2.44e-04	13	41	2	ctd:C046855
Drug	AC1L2AC7	CACNA1A CACNA1D CACNA1S	2.61e-04	69	41	3	CID000068733
Drug	papaverine	CACNA1A CACNA1D CACNA1S ADORA3	2.80e-04	176	41	4	CID000004680
Drug	Barium	TRPM6 CACNA1A CACNA1D	2.97e-04	72	41	3	ctd:D001464
Drug	AC1L1JVU	CACNA1D CACNA1S TRPM7	2.97e-04	72	41	3	CID000005229
Drug	CAS 298-57-7	CACNA1A CACNA1D CACNA1S	3.09e-04	73	41	3	CID000002761
Drug	NSC7524	CACNA1A CACNA1D CACNA1S ADORA3	3.18e-04	182	41	4	CID000005657
Drug	ethosuximide	CACNA1A CACNA1D CACNA1S	3.21e-04	74	41	3	CID000003291
Drug	FPL 64176	CACNA1D CACNA1S	3.27e-04	15	41	2	CID000003423
Drug	DM-nitrophen	CACNA1A CACNA1S	3.74e-04	16	41	2	CID000003083
Drug	nisoldipine	CACNA1A CACNA1D CACNA1S	3.75e-04	78	41	3	CID000004499
Drug	baclofen	CACNA1A CACNA1D CACNA1S ADORA3	3.81e-04	191	41	4	CID000002284
Drug	N-cyclopentyl-N-cyclobutylformamide	CACNA1A CACNA1D CACNA1S	3.90e-04	79	41	3	CID005287890
Disease	posterior uveitis (is_implicated_in)	CCR2 CCR5	5.37e-06	3	40	2	DOID:12574 (is_implicated_in)
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1D CACNA1S	1.07e-05	4	40	2	DOID:0060173 (implicated_via_orthology)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	SLC6A5 CACNA1D CACNA1S	1.60e-05	36	40	3	DOID:11723 (implicated_via_orthology)
Disease	hereditary spastic paraplegia 31 (implicated_via_orthology)	REEP4 REEP5	2.68e-05	6	40	2	DOID:0110782 (implicated_via_orthology)
Disease	urticaria (is_implicated_in)	CCR2 CCR5	4.99e-05	8	40	2	DOID:1555 (is_implicated_in)
Disease	Coronavirus infectious disease (implicated_via_orthology)	CCR2 CCR5	6.41e-05	9	40	2	DOID:0080599 (implicated_via_orthology)
Disease	Kawasaki disease (is_implicated_in)	CCR2 CCR5	1.17e-04	12	40	2	DOID:13378 (is_implicated_in)
Disease	response to triptolide, cytotoxicity measurement	TECRL LRRC3B	2.12e-04	16	40	2	EFO_0006952, EFO_0007662
Disease	–	CCR2 CCR5	2.12e-04	16	40	2	609423
Disease	Susceptibility to HIV infection	CCR2 CCR5	2.12e-04	16	40	2	cv:C1836230
Disease	sarcoidosis (is_implicated_in)	CCR2 CCR5	2.12e-04	16	40	2	DOID:11335 (is_implicated_in)
Disease	interstitial lung disease (is_marker_for)	CCR2 CCR5	5.27e-04	25	40	2	DOID:3082 (is_marker_for)
Disease	type 2 diabetes mellitus (is_marker_for)	CCR2 CACNA1D CCR5	8.35e-04	136	40	3	DOID:9352 (is_marker_for)
Disease	atopic dermatitis (is_marker_for)	CCR2 CCR5	1.04e-03	35	40	2	DOID:3310 (is_marker_for)
Disease	Adenoma	CACNA1D TRPM7	1.10e-03	36	40	2	C0001430
Disease	Adenoma, Microcystic	CACNA1D TRPM7	1.10e-03	36	40	2	C0205648
Disease	Adenoma, Monomorphic	CACNA1D TRPM7	1.10e-03	36	40	2	C0205649
Disease	Adenoma, Basal Cell	CACNA1D TRPM7	1.10e-03	36	40	2	C0205646
Disease	Follicular adenoma	CACNA1D TRPM7	1.10e-03	36	40	2	C0205647
Disease	Papillary adenoma	CACNA1D TRPM7	1.10e-03	36	40	2	C0205650
Disease	Adenoma, Trabecular	CACNA1D TRPM7	1.10e-03	36	40	2	C0205651
Disease	asthma (is_implicated_in)	CCR2 CCR5 NPSR1	1.26e-03	157	40	3	DOID:2841 (is_implicated_in)
Disease	human immunodeficiency virus infectious disease (is_implicated_in)	CCR2 CCR5	1.29e-03	39	40	2	DOID:526 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
YRMWQFVVSPPFEYT	CACNA1A	1556	O00555
YMVYFSFLTWIFIPL	ADORA3	176	P0DMS8
WVTNFIYDMVFYLVP	ABCA12	2031	Q86UK0
MIVYFLFWAPYNIVL	CCR5	241	P51681
VFMRTWYPVSIPAFY	BMS1	1096	Q14692
ITPSYVFMVWYEFCS	FMN1	1346	Q68DA7
SFRAYTSVLYFNPWM	MORC1	236	Q86VD1
MWQEYYFLNVFFPLL	OR2T1	1	O43869
YWTPYMTIVAFLVYF	NPSR1	206	Q6W5P4
AFTSLPVYMYFNLWT	GPM6A	146	P51674
YNFYRWFPSGKVVFM	FANCM	126	Q8IYD8
LSQIYDWMVRYVPYF	FOXO6	111	A8MYZ6
FGWFTMVISYVVYYV	LRRC3B	211	Q96PB8
FPTAVFMYWLSSNLF	OXA1L	311	Q15070
YSMYIAVFIQPFPWS	MFSD11	86	O43934
TSVFYMLWLPYIIYF	GPR52	271	Q9Y2T5
RMVIYFFIAASYAPW	MMD	101	Q15546
LYFYKVWLPLFMPVY	FADS2B	301	A8MWK0
FYVSIQSYWLSFFMV	GPR160	176	Q9UJ42
VWYIVTSSYFEYLMF	CACNA1S	1111	Q13698
FQTLMFLIRDWSYPY	ATL2	236	Q8NHH9
FTIMIVYFLFWTPYN	CCR2	246	P41597
SFFAKYWMYIIPVVL	EMC10	221	Q5UCC4
HPLYFWFYFVFMNAL	EBP	181	Q15125
WLFYTIMAYTPTYIS	SLC17A4	306	Q9Y2C5
YIPLFIWTYMFHTVD	CDH9	6	Q9ULB4
YKFWYVVNSSPFEYM	CACNA1D	1196	Q01668
DIFISWFPFYYEIKM	REEP4	56	Q9H6H4
FILCFSFYQWEPMTY	SLC6A5	691	Q9Y345
MAWVSFYLLPFIFST	IGLV4-3	1	A0A075B6K6
FFSDIFLSWFPFYYM	REEP5	101	Q00765
FSTNWNIMFFPVYYS	SLC35F4	201	A4IF30
WYIPFFLILFMYFSG	CLN6	181	Q9NWW5
QFLSMTWYSLSYIPY	SFT2D1	131	Q8WV19
VYPVFLFYFVISWMI	YIPF6	216	Q96EC8
ISPQFYATFWSLTMY	THOC2	876	Q8NI27
SAPIVKFWFYTMAYL	TRPM6	836	Q9BX84
IFIEMYFIFTSFWAY	TM9SF3	461	Q9HD45
FTWMFFLVSCPNYTY	TECRL	291	Q5HYJ1
WNLYVFALMFLYAPS	WLS	481	Q5T9L3
YGYSLFVFIPMVVLW	YIPF2	206	Q9BWQ6
IVFHPYWMIFGEVYA	TRPM7	1036	Q96QT4
FFAAYTLWFFAVPVM	TMEM145	351	Q8NBT3