Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionWnt receptor activity

FZD3 RYK

3.33e-0417322GO:0042813
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR51G2 OR51D1 GRIN2D FZD3 OR2L13 RYK CNR1 OR2AJ1

1.06e-031353328GO:0004888
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIN2D ITPR3

1.12e-0331322GO:0099604
GeneOntologyMolecularFunctionWnt-protein binding

FZD3 RYK

1.35e-0334322GO:0017147
GeneOntologyBiologicalProcessdopaminergic neuron axon guidance

FZD3 RYK

3.48e-056322GO:0036514
GeneOntologyBiologicalProcesscell proliferation in midbrain

FZD3 RYK

6.49e-058322GO:0033278
GeneOntologyCellularComponentpresynaptic active zone membrane

GRIN2D FZD3 RYK

2.29e-0478323GO:0048787
DomainOlfact_rcpt

OR51G2 OR51D1 OR2L13 OR2AJ1

4.36e-03393324IPR000725
Domain7tm_1

OR51G2 OR51D1 OR2L13 CNR1 OR2AJ1

5.51e-03677325PF00001
DomainG_PROTEIN_RECEP_F1_1

OR51G2 OR51D1 OR2L13 CNR1 OR2AJ1

5.79e-03685325PS00237
DomainG_PROTEIN_RECEP_F1_2

OR51G2 OR51D1 OR2L13 CNR1 OR2AJ1

6.01e-03691325PS50262
DomainGPCR_Rhodpsn

OR51G2 OR51D1 OR2L13 CNR1 OR2AJ1

6.04e-03692325IPR000276
Pubmed

An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction.

CNR1 ITPR3

2.46e-06332226037800
Pubmed

Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.

CSNK2A2 ITPR3

4.92e-06432214685260
Pubmed

Planar cell polarity signaling components are a direct target of β-amyloid-associated degeneration of glutamatergic synapses.

FZD3 RYK

8.19e-06532234407949
Pubmed

Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem.

FZD3 RYK

3.67e-051032221106844
Pubmed

Expression and functional analysis of Dkk1 during early gonadal development.

SP5 AMH

1.11e-041732221654186
Pubmed

Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.

FZD3 RYK

1.39e-041932226490861
Pubmed

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.

HYDIN ITPR3

1.70e-042132226234751
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR51G2 OR51D1 OR2L13 OR2AJ1

2.60e-0434032411875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR51G2 OR51D1 OR2L13 OR2AJ1

2.60e-0434032411802173
Pubmed

Identification of novel markers of mouse fetal ovary development.

AMH PANK1

2.63e-042632222844512
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR51G2 OR51D1 OR2L13 OR2AJ1

2.69e-0434332432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR51G2 OR51D1 OR2L13 OR2AJ1

2.78e-0434632414611657
Pubmed

Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages.

SP5 CASZ1

3.51e-043032235320729
Pubmed

Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear.

SP5 FZD3

4.25e-043332224727668
Pubmed

Ovarian development in mice requires the GATA4-FOG2 transcription complex.

SP5 AMH

5.07e-043632218927154
Cytoband1q44

OR2L13 OR2AJ1

2.69e-031103221q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2L13 OR2AJ1

3.62e-03128322chr1q44
Cytoband11p15.4

OR51G2 OR51D1

8.60e-0320032211p15.4
GeneFamilyOlfactory receptors, family 51

OR51G2 OR51D1

1.81e-0344262164
GeneFamilyOlfactory receptors, family 2

OR2L13 OR2AJ1

1.14e-02113262149
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

HYDIN ITPR3

2.77e-02181262694
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC25B POLM CASZ1 PIF1

8.34e-061813243fe648db1cb8326066d8bde3ca1287c5c9af19bd
DiseaseHypermetropia, Myopia

CUBN RYK PPM1E

9.24e-04189303HP_0000540, HP_0000545
Diseaseobesity (implicated_via_orthology)

PNPLA1 CNR1 ITPR3

1.34e-03215303DOID:9970 (implicated_via_orthology)
Diseasepyruvate measurement

SERPINB8 HYDIN HACE1

2.51e-03268303EFO_0010117
DiseaseSelf-injurious behavior

POLM CNR1

2.86e-0378302HP_0100716
Diseaseschizophrenia (is_implicated_in)

FZD3 CNR1

2.86e-0378302DOID:5419 (is_implicated_in)
DiseaseModerate albuminuria

CUBN CASZ1

3.01e-0380302HP_0012594
DiseaseNerve Degeneration

GRIN2D CNR1

3.23e-0383302C0027746
DiseaseWeight Gain

RYK CNR1

4.83e-03102302C0043094
Diseasetreatment-resistant hypertension

CASZ1 HACE1

5.50e-03109302EFO_1002006
Diseaseneuroblastoma

SERPINB8 HACE1

6.20e-03116302EFO_0000621
Diseasepursuit maintenance gain measurement

SERPINB8 CSNK2A2

6.95e-03123302EFO_0008433

Protein segments in the cluster

PeptideGeneStartEntry
DADPDDKFHCLRLFR

PRPF4B

741

Q13523
SLQHGFMRFSPLDDC

CASZ1

521

Q86V15
HMDAFERSFCIFRLP

POLM

381

Q9NP87
DEMLPFDLRASFCHL

ITPR3

766

Q14573
RISPSSCLMDRHDFG

IFNA1;

46

P01562
MAFDRFVAICHPLRH

OR51D1

131

Q8NGF3
LSMAFDRFVAICHPL

OR51G2

121

Q8NGK0
HFHFLLECPELMSRF

HACE1

501

Q8IYU2
PRDCPAIFHDFRMFN

PNPLA1

201

Q8N8W4
HCEFSSERGPRMCRF

CDC25B

486

P30305
GDDHRCFTRMTPALL

AMH

236

P03971
LDSHARARPDMFCLF

CHRDL2

21

Q6WN34
EMFPHDPAEALCRAF

PPM1E

296

Q8WY54
FTFFRLESMDNCPHE

CUBN

516

O60494
MDDPCFSHRSRRKLA

HYDIN

1576

Q4G0P3
RSLMFCDFHDPKRED

DNAH7

2266

Q8WXX0
LLPFERDAHSAAAMA

A3GALT2

231

U3KPV4
SKDLRHAFRSMFPSC

CNR1

401

P21554
CMLASMIFRREPFFH

CSNK2A2

221

P19784
HPMVNLDCSRDFRPF

FZD3

66

Q9NPG1
PDCHDMFEHGSFLRR

FOXS1

96

O43638
LSRDLFPMDYHCLGD

RYK

486

P34925
SRAIDHFFCEVPAML

OR2AJ1

171

Q8NGZ0
NLHFIRFPSCAMHRF

PANK1

306

Q8TE04
RAIDHFFCDVPAMLL

OR2L13

171

Q8N349
FDPMAVRCDPRVLHF

PIF1

596

Q9H611
FACPECGKRFMRSDH

SP5

356

Q6BEB4
FPPLFMEAFSRRHCE

PRAMEF20

36

Q5VT98
FTCDSDHLRPADAIM

ST7

176

Q9NRC1
SRMEPRFCADHPFLF

SERPINB8

341

P50452
RLCEIFTRMFADPHS

CLASP1

896

Q7Z460
FSLSACFREHVRMHP

ZNF555

461

Q8NEP9
FRSPFRLRAADNCMS

ZMYND15

671

Q9H091
CLGPTHRMDFLLAFS

GRIN2D

876

O15399