Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	signaling adaptor activity	SHANK1 KSR1 KHDRBS1 KSR2	1.40e-04	129	41	4	GO:0035591
GeneOntologyMolecularFunction	MAP-kinase scaffold activity	KSR1 KSR2	3.16e-04	13	41	2	GO:0005078
GeneOntologyMolecularFunction	mitogen-activated protein kinase kinase binding	KSR1 KSR2	6.88e-04	19	41	2	GO:0031434
GeneOntologyMolecularFunction	RNA cap binding	LARP1 LARP1B	8.43e-04	21	41	2	GO:0000339
GeneOntologyMolecularFunction	histone modifying activity	HDAC9 RSBN1 JADE2 KDM4B	1.22e-03	229	41	4	GO:0140993
GeneOntologyMolecularFunction	poly(A) binding	PAN3 KHDRBS1	1.61e-03	29	41	2	GO:0008143
GeneOntologyMolecularFunction	histone demethylase activity	RSBN1 KDM4B	1.84e-03	31	41	2	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	RSBN1 KDM4B	1.96e-03	32	41	2	GO:0140457
GeneOntologyMolecularFunction	poly-purine tract binding	PAN3 KHDRBS1	2.62e-03	37	41	2	GO:0070717
Domain	DM15	LARP1 LARP1B	4.03e-06	2	38	2	SM00684
Domain	KSR1-SAM	KSR1 KSR2	4.03e-06	2	38	2	PF13543
Domain	DM15	LARP1 LARP1B	4.03e-06	2	38	2	IPR006607
Domain	KSR_SAM-like_dom	KSR1 KSR2	4.03e-06	2	38	2	IPR025561
Domain	NUT	NUTM2B NUTM2A	4.02e-05	5	38	2	IPR024310
Domain	NUT_N	NUTM2B NUTM2A	4.02e-05	5	38	2	IPR024309
Domain	NUT	NUTM2B NUTM2A	4.02e-05	5	38	2	PF12881
Domain	La	LARP1 LARP1B	8.41e-05	7	38	2	PF05383
Domain	Lupus_La_RNA-bd	LARP1 LARP1B	8.41e-05	7	38	2	IPR006630
Domain	LA	LARP1 LARP1B	8.41e-05	7	38	2	SM00715
Domain	HTH_LA	LARP1 LARP1B	8.41e-05	7	38	2	PS50961
Domain	EPHD	JADE2 KDM4B	9.08e-04	22	38	2	PS51805
Domain	C1_1	KSR1 KSR2	6.00e-03	57	38	2	PF00130
Domain	ZF_DAG_PE_1	KSR1 KSR2	7.51e-03	64	38	2	PS00479
Domain	ZF_DAG_PE_2	KSR1 KSR2	7.51e-03	64	38	2	PS50081
Domain	C1	KSR1 KSR2	7.73e-03	65	38	2	SM00109
Domain	PE/DAG-bd	KSR1 KSR2	7.97e-03	66	38	2	IPR002219
Domain	SAM_1	SHANK1 CASKIN2	8.44e-03	68	38	2	PF00536
Domain	Ank_2	SHANK1 ANKRD6 CASKIN2	9.44e-03	215	38	3	PF12796
Domain	PHD	JADE2 KDM4B	1.02e-02	75	38	2	PF00628
Domain	Ank	SHANK1 ANKRD6 CASKIN2	1.11e-02	228	38	3	PF00023
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	SLAIN2 SRRM1 KHDRBS1 ATXN2 CASKIN2	2.30e-07	108	43	5	19531213
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	LARP1 SRRM1 RBM15 KHDRBS1 ATXN2	3.02e-07	114	43	5	31553912
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SLAIN2 LARP1 SRRM1 KSR1 RBM15 LARP1B PAN3 NCKAP5L CASKIN2	8.88e-07	861	43	9	36931259
Pubmed	Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK.	KSR1 KSR2	1.49e-06	2	43	2	22801368
Pubmed	KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity.	KSR1 KSR2	1.49e-06	2	43	2	19883615
Pubmed	Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis.	KSR1 KSR2	1.49e-06	2	43	2	28180061
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	LARP1 SRRM1 RBM15 LRRC59 LARP1B PAN3 KHDRBS1 ATXN2	1.59e-06	678	43	8	30209976
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	LARP1 RSBN1 SRRM1 RBM15 LRRC59 KHDRBS1 NUTM2B ATXN2 NUTM2A	2.07e-06	954	43	9	36373674
Pubmed	The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.	NUTM2B NUTM2A	4.48e-06	3	43	2	22456610
Pubmed	Oncoprotein Cot1 represses kinase suppressors of Ras1/2 and 1,25-dihydroxyvitamin D3-induced differentiation of human acute myeloid leukemia cells.	KSR1 KSR2	4.48e-06	3	43	2	20945381
Pubmed	Histone demethylase JMJD2B and JMJD2C induce fibroblast growth factor 2: mediated tumorigenesis of osteosarcoma.	FGF2 KDM4B	4.48e-06	3	43	2	25636512
Pubmed	KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals.	KSR1 KSR2	4.48e-06	3	43	2	19560418
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	4.48e-06	3	43	2	26542179
Pubmed	The KSR2-calcineurin complex regulates STIM1-ORAI1 dynamics and store-operated calcium entry (SOCE).	KSR1 KSR2	1.49e-05	5	43	2	24672054
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	SHANK1 LARP1 PAN3 KHDRBS1 ATXN2 TENM2	2.14e-05	462	43	6	31138677
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	LARP1 LARP1B PAN3 KHDRBS1 ATXN2	2.20e-05	274	43	5	34244482
Pubmed	HiQuant: Rapid Postquantification Analysis of Large-Scale MS-Generated Proteomics Data.	KSR1 KSR2	2.23e-05	6	43	2	27086506
Pubmed	HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.	HDAC9 FGF2	2.23e-05	6	43	2	19351956
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	LARP1 SRRM1 RBM15 LRRC59 LARP1B KHDRBS1 ATXN2	2.51e-05	713	43	7	29802200
Pubmed	MEK drives BRAF activation through allosteric control of KSR proteins.	KSR1 KSR2	3.12e-05	7	43	2	29433126
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	LARP1 RSBN1 SRRM1 RBM15 LRRC59 LARP1B ATXN2 C2orf68 NUTM2A	3.76e-05	1371	43	9	36244648
Pubmed	Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.	CACNA1D ACACB MXI1	4.42e-05	55	43	3	27997827
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SLAIN2 LARP1 FAM149B1 CASKIN2 JADE2 KDM4B	4.55e-05	529	43	6	14621295
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	SLAIN2 LARP1 RBM15 KHDRBS1 ATXN2 UBR4	5.70e-05	551	43	6	34728620
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	RSBN1 SRRM1 RBM15 ACACB ATXN2	9.16e-05	370	43	5	22922362
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	SLAIN2 LARP1 RSBN1 KHDRBS1	1.67e-04	223	43	4	33731348
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	LARP1 SRRM1 RBM15 LRRC59 LARP1B KHDRBS1 ATXN2	1.73e-04	971	43	7	33306668
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ACACB NYAP1 ATXN2 C2orf68 UBR4	1.85e-04	430	43	5	35044719
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SRRM1 RBM15 ACACB KHDRBS1	2.01e-04	234	43	4	36243803
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	LARP1 SRRM1 RBM15 LRRC59 KHDRBS1	2.07e-04	441	43	5	31239290
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	LARP1 SRRM1 LRRC59 KHDRBS1	2.17e-04	239	43	4	26641092
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	LARP1 KSR1 RBM15 ACACB NCKAP5L	2.19e-04	446	43	5	24255178
Pubmed	Recruitment of the human TREX complex to mRNA during splicing.	SRRM1 RBM15	2.80e-04	20	43	2	15998806
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	LARP1 RBM15 LARP1B ATXN2	2.91e-04	258	43	4	37794589
Pubmed	Human transcription factor protein interaction networks.	LARP1 RSBN1 LRRC59 PAN3 ACACB KHDRBS1 ATXN2 UBR4	3.20e-04	1429	43	8	35140242
Pubmed	A human MAP kinase interactome.	SHANK1 HDAC9 KHDRBS1 NCKAP5L JADE2	3.24e-04	486	43	5	20936779
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	SLAIN2 SMTNL2	3.40e-04	22	43	2	22305495
Pubmed	Chromosomal mapping of five highly conserved murine homologues of the Drosophila RING finger gene seven-in-absentia.	FGF2 MXI1	3.72e-04	23	43	2	9143490
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	LARP1 LARP1B SIPA1 ACACB UBR4	3.80e-04	503	43	5	36217030
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SLAIN2 HRES1 RSBN1 SRRM1 KSR1 SIPA1 NCKAP5L	4.03e-04	1116	43	7	31753913
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	LARP1 SRRM1 RBM15 LARP1B KHDRBS1 ATXN2	4.49e-04	807	43	6	22681889
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	SLAIN2 KHDRBS1 UBR4	5.65e-04	130	43	3	35545047
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	LARP1 SRRM1 RBM15 LRRC59 KHDRBS1 JADE2	5.79e-04	847	43	6	35850772
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HDAC9 KHDRBS1 ANKRD6 JADE2 KDM4B MXI1	6.95e-04	877	43	6	20211142
Pubmed	Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.	LARP1 ATXN2	7.23e-04	32	43	2	19542561
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	LARP1 SRRM1 KHDRBS1 CASKIN2	7.25e-04	329	43	4	34316702
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	LARP1 FGF2 SRRM1 RBM15	7.50e-04	332	43	4	25693804
Pubmed	The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.	CACNA1D FAM149B1	7.69e-04	33	43	2	22357600
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	LARP1 SRRM1 RBM15 LRRC59 KHDRBS1	8.74e-04	605	43	5	28977666
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	LARP1 SRRM1 RBM15 KHDRBS1 NCKAP5L ATXN2	9.01e-04	922	43	6	27609421
Pubmed	SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.	LARP1 LRRC59 KHDRBS1 ADAMTSL4	9.42e-04	353	43	4	27545878
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	LARP1 SRRM1 RBM15 KHDRBS1	1.02e-03	361	43	4	30344098
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SRRM1 RBM15 KHDRBS1 UBR4	1.02e-03	361	43	4	26167880
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	LARP1 SRRM1 KHDRBS1 ATXN2	1.06e-03	364	43	4	24778252
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	LARP1 RSBN1 SRRM1 RBM15 LRRC59 ACACB UBR4	1.08e-03	1318	43	7	30463901
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	LARP1 SRRM1 LRRC59	1.09e-03	163	43	3	22113938
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 SIPA1 ATXN2 TENM2 UBR4 KSR2	1.13e-03	963	43	6	28671696
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	CACNA1D PAN3 JADE2 KDM4B	1.13e-03	371	43	4	15747579
Pubmed	Comparative Proteomics and Interactome Analysis of the SARS-CoV-2 Nucleocapsid Protein in Human and Bat Cell Lines.	LARP1 LRRC59 KHDRBS1	1.19e-03	168	43	3	39066279
Pubmed	Spatially dependent dynamic MAPK modulation by the Nde1-Lis1-Brap complex patterns mammalian CNS.	KSR1 KSR2	1.19e-03	41	43	2	23673330
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	LARP1B NCKAP5L UBR4	1.23e-03	170	43	3	23314748
Interaction	YWHAH interactions	SLAIN2 LARP1 SRRM1 KSR1 RBM15 LARP1B PAN3 SIPA1 NCKAP5L CASKIN2 SMTNL2 KSR2	1.62e-06	1102	42	12	int:YWHAH
Interaction	YWHAG interactions	SLAIN2 LARP1 SRRM1 KSR1 RBM15 LARP1B PAN3 SIPA1 NCKAP5L CASKIN2 SMTNL2 KSR2	5.87e-06	1248	42	12	int:YWHAG
Cytoband	10q23.2	NUTM2D NUTM2A	1.16e-04	17	43	2	10q23.2
Cytoband	10q22.3	NUTM2E NUTM2B	7.55e-04	43	43	2	10q22.3
Cytoband	Ensembl 112 genes in cytogenetic band chr10q22	NUTM2E FAM149B1 NUTM2B	9.90e-04	208	43	3	chr10q22
Cytoband	Ensembl 112 genes in cytogenetic band chr4q28	FGF2 LARP1B	2.65e-03	81	43	2	chr4q28
Cytoband	17q11.2	TP53I13 KSR1	4.82e-03	110	43	2	17q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr12q24	ACACB ATXN2 KSR2	6.92e-03	415	43	3	chr12q24
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	KSR1 KSR2	1.28e-05	5	21	2	1157
GeneFamily	La ribonucleoprotein domain containing\|RNA binding motif containing	LARP1 LARP1B	2.69e-05	7	21	2	625
GeneFamily	Ankyrin repeat domain containing	SHANK1 ANKRD6 CASKIN2	2.64e-03	242	21	3	403
GeneFamily	Sterile alpha motif domain containing	SHANK1 CASKIN2	4.63e-03	88	21	2	760
GeneFamily	PDZ domain containing	SHANK1 SIPA1	1.33e-02	152	21	2	1220
Computational	Neighborhood of CBFB	SRRM1 RBM15 KHDRBS1	2.17e-05	30	20	3	GNF2_CBFB
Drug	Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; HL60; HG-U133A	ACACB ATXN2 JADE2 ADAMTSL4 KDM4B ZNF710	1.44e-06	199	41	6	1739_UP
Disease	Endometrial Stromal Sarcoma	NUTM2B NUTM2A	1.79e-05	5	40	2	C0206630
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	2.68e-05	6	40	2	C0334488
Disease	Antihypertensive use measurement	HDAC9 CACNA1D SRRM1 ATXN2 KDM4B	2.86e-05	265	40	5	EFO_0009927
Disease	monocyte count	OSER1 RSBN1 KSR1 PAN3 NYAP1 ATXN2 JADE2 KDM4B MXI1	5.44e-05	1320	40	9	EFO_0005091
Disease	platelet component distribution width	OSER1 HDAC9 SRRM1 NYAP1 ATXN2 JADE2 ZNF710	6.24e-05	755	40	7	EFO_0007984
Disease	event free survival time, type 1 diabetes mellitus, autoantibody measurement	RSBN1 ATXN2	1.17e-04	12	40	2	EFO_0000482, EFO_0004866, MONDO_0005147
Disease	Ischemic stroke, tissue plasminogen activator measurement	HDAC9 ATXN2	1.86e-04	15	40	2	EFO_0004791, HP_0002140
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	HDAC9 ATXN2	2.12e-04	16	40	2	EFO_0004792, HP_0002140
Disease	factor XI measurement, Ischemic stroke	HDAC9 ATXN2	2.41e-04	17	40	2	EFO_0004694, HP_0002140
Disease	lymphocyte percentage of leukocytes	OSER1 HDAC9 FGF2 ATXN2 KDM4B ZNF710	2.56e-04	665	40	6	EFO_0007993
Disease	factor VIII measurement, Ischemic stroke	HDAC9 ATXN2	3.02e-04	19	40	2	EFO_0004630, HP_0002140
Disease	inflammatory bowel disease	SLAIN2 HDAC9 KSR1 ATXN2 UBR4	3.39e-04	449	40	5	EFO_0003767
Disease	monocyte percentage of leukocytes	OSER1 KSR1 PAN3 ATXN2 JADE2 KDM4B	4.24e-04	731	40	6	EFO_0007989
Disease	mean arterial pressure	HDAC9 CACNA1D SIPA1 ATXN2 KDM4B	5.47e-04	499	40	5	EFO_0006340
Disease	systemic lupus erythematosus	RSBN1 KSR1 SIPA1 ATXN2 KDM4B KSR2	6.77e-04	799	40	6	MONDO_0007915
Disease	Ischemic stroke, factor VII measurement	HDAC9 ATXN2	7.11e-04	29	40	2	EFO_0004619, HP_0002140
Disease	response to angiotensin receptor blocker	CACNA1D TENM2	7.61e-04	30	40	2	EFO_0010735
Disease	Ischemic stroke, von Willebrand factor measurement	HDAC9 ATXN2	7.61e-04	30	40	2	EFO_0004629, HP_0002140
Disease	coronary artery disease	HDAC9 RSBN1 SIPA1 ANKRD6 ATXN2 KDM4B KSR2	1.01e-03	1194	40	7	EFO_0001645
Disease	bipolar disorder	SLAIN2 HDAC9 ANKRD6 JADE2 MXI1	1.05e-03	577	40	5	MONDO_0004985
Disease	neutrophil percentage of leukocytes	OSER1 HDAC9 FGF2 ATXN2 KDM4B	1.34e-03	610	40	5	EFO_0007990
Disease	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	RSBN1 ATXN2	1.35e-03	40	40	2	EFO_1001999, EFO_1002019, EFO_1002020
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	KSR1 ATXN2 SMTNL2	1.59e-03	170	40	3	EFO_0000685, EFO_0007791, EFO_0007837
Disease	breast cancer (is_marker_for)	FGF2 KSR1 KDM4B	2.02e-03	185	40	3	DOID:1612 (is_marker_for)
Disease	health study participation	JADE2 TENM2 KDM4B	2.35e-03	195	40	3	EFO_0010130
Disease	mean platelet volume	HDAC9 RSBN1 SRRM1 ZNF324B ATXN2 ZNF710	2.36e-03	1020	40	6	EFO_0004584
Disease	peripheral arterial disease	HDAC9 ATXN2	2.45e-03	54	40	2	EFO_0004265
Disease	diastolic blood pressure, alcohol consumption measurement	SIPA1 ATXN2	2.45e-03	54	40	2	EFO_0006336, EFO_0007878
Disease	comparative body size at age 10, self-reported	CACNA1D NYAP1 ZNF710 KSR2	2.47e-03	420	40	4	EFO_0009819
Disease	Ischemic stroke, fibrinogen measurement	HDAC9 ATXN2	2.54e-03	55	40	2	EFO_0004623, HP_0002140
Disease	Crohn's disease	SLAIN2 RSBN1 KSR1 ATXN2	2.94e-03	441	40	4	EFO_0000384
Disease	lymphocyte count	OSER1 HDAC9 FGF2 RSBN1 ATXN2 KDM4B ZNF710	3.22e-03	1464	40	7	EFO_0004587
Disease	rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement	RSBN1 ATXN2	3.32e-03	63	40	2	EFO_0000685, EFO_0007791, EFO_0009459
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	HDAC9 ATXN2	3.32e-03	63	40	2	EFO_0001645, EFO_0004792
Disease	cardiovascular disease	CACNA1D SRRM1 ATXN2 MXI1	3.34e-03	457	40	4	EFO_0000319
Disease	rheumatoid arthritis	RSBN1 KSR1 ATXN2 SMTNL2	3.47e-03	462	40	4	EFO_0000685
Disease	sclerosing cholangitis	HDAC9 ATXN2	3.64e-03	66	40	2	EFO_0004268
Disease	tissue plasminogen activator measurement, coronary artery disease	HDAC9 ATXN2	4.20e-03	71	40	2	EFO_0001645, EFO_0004791

Protein segments in the cluster

Peptide	Gene	Start	Entry
LPLHRNRRHPRSPPR	ADAMTSL4	166	Q6UY14
VRRRHTPAPTRPRKP	C2orf68	51	Q2NKX9
PKKRNRHRCSSPPPP	ANKRD6	371	Q9Y2G4
RPRKRHCAPSPDRSP	RBM15	661	Q96T37
KRSRRRPLLPPTPDS	TP53I13	371	Q8NBR0
GRRRNSLPPSHQKPP	ACACB	86	O00763
EKLASRPTRPPEPRH	LARP1	266	Q6PKG0
ARPPPLTKVPRRAHT	NCKAP5L	1161	Q9HCH0
SRPRKPPPRKHTRSW	LRRC59	231	Q96AG4
PRLSPKTHRPRSPRQ	ATXN2	681	Q99700
PPHRRPTLHRRPTLP	KIAA2026	351	Q5HYC2
SPRQRHAVRTPPRTP	KSR2	251	Q6VAB6
GPPTRKPPRRTSSHL	JADE2	641	Q9NQC1
QLRRHTKLKPPRTPP	KSR1	276	Q8IVT5
RRHPLGRPPTRSPLS	KDM4B	611	O94953
TPPRSVPRLRPRHRH	HRES1	31	P13985
PPRPKRRSHSLSRPG	CASKIN2	791	Q8WXE0
SPKITPHTSPAPRRR	PAN3	346	Q58A45
PLHTRPRVPAPKTRN	ITIH6	821	Q6UXX5
ALPRRRPRRHPSVNP	FGF2	41	P09038
RQTPSRQPPLPHRSR	KHDRBS1	31	Q07666
PRHRPLNRTQSAPLP	HDAC9	441	Q9UKV0
PRPSVPRTLPGSRHK	CABLES2	266	Q9BTV7
PRRRLLPPTPASHRR	CACNA1D	1906	Q01668
IHPTRTPKTPRTPRL	LARP1B	596	Q659C4
TRRRNPPPRTLHPIS	FAM149B1	416	Q96BN6
TRRPPAKPRRHPSTK	NYAP1	111	Q6ZVC0
PPPRPHRRAETKARL	NUTM2A	481	Q8IVF1
HRRAETKARLPPPRP	NUTM2A	486	Q8IVF1
PPPRPHRRAETKARL	NUTM2B	481	A6NNL0
HRRAETKARLPPPRP	NUTM2B	486	A6NNL0
PRPHRRAETKARLPP	NUTM2D	411	Q5VT03
PPPQPHRRAETKARL	NUTM2E	481	B1AL46
HRRAETKARLPPPRP	NUTM2E	486	B1AL46
EPPLAPPHRRRRSRQ	RSBN1	106	Q5VWQ0
RPSPKQSPRNSPRSR	SLAIN2	351	Q9P270
RKLRQPARPPLTPHT	SIPA1	26	Q96FS4
TPPPRLLPRNTFSRK	TENM2	346	Q9NT68
TQRRRRSKSPVLHPP	OSER1	76	Q9NX31
SPPAARRSLLHRLPP	SHANK1	1436	Q9Y566
SPQPRLPPSRHPSRR	TYMSOS	81	Q8TAI1
QRRYSPSPPPKRRTA	SRRM1	601	Q8IYB3
PKRRVSHSPPPKQRS	SRRM1	631	Q8IYB3
RKPRTLRHLPRTPRP	ZNF710	166	Q8N1W2
PRPRPVSLSLRLPHQ	SMTNL2	181	Q2TAL5
RPRNKRRHVTLPSSP	UBR4	2706	Q5T4S7
RLTSPLRPPKSSRPR	ZNF324B	161	Q6AW86
SMPSPRLQHSKPPRR	MXI1	36	P50539