Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	SPRY	BSPRY TRIM47 RYR1	1.81e-03	94	48	3	PF00622
Domain	SPRY_dom	BSPRY TRIM47 RYR1	1.81e-03	94	48	3	IPR003877
Domain	B30.2/SPRY	BSPRY TRIM47 RYR1	1.87e-03	95	48	3	IPR001870
Domain	B302_SPRY	BSPRY TRIM47 RYR1	1.87e-03	95	48	3	PS50188
Domain	ConA-like_dom	BSPRY TRIM47 RYR1 CRB2	2.39e-03	219	48	4	IPR013320
Domain	EF_hand_dom	NKD1 RHOT2 ZZEF1 RYR1	2.94e-03	232	48	4	IPR002048
Domain	JMJC	JMJD7 HR	3.05e-03	32	48	2	PS51184
Domain	JmjC_dom	JMJD7 HR	3.05e-03	32	48	2	IPR003347
Domain	JmjC	JMJD7 HR	3.25e-03	33	48	2	SM00558
Domain	-	NKD1 RHOT2 ZZEF1 RYR1	4.48e-03	261	48	4	1.10.238.10
Domain	-	ZFP36L2 UNKL	4.74e-03	40	48	2	4.10.1000.10
Domain	Ldl_recept_a	SPINT1 TMPRSS6	5.97e-03	45	48	2	PF00057
Domain	-	SPINT1 TMPRSS6	6.23e-03	46	48	2	4.10.400.10
Domain	EF-hand-dom_pair	NKD1 RHOT2 ZZEF1 RYR1	6.25e-03	287	48	4	IPR011992
Domain	PRY	BSPRY TRIM47	6.77e-03	48	48	2	SM00589
Domain	ZnF_C3H1	ZFP36L2 UNKL	6.77e-03	48	48	2	SM00356
Domain	LDLRA_1	SPINT1 TMPRSS6	6.77e-03	48	48	2	PS01209
Domain	PRY	BSPRY TRIM47	6.77e-03	48	48	2	IPR006574
Domain	zf-CCCH	ZFP36L2 UNKL	7.04e-03	49	48	2	PF00642
Domain	LDLRA_2	SPINT1 TMPRSS6	7.04e-03	49	48	2	PS50068
Domain	LDrepeatLR_classA_rpt	SPINT1 TMPRSS6	7.04e-03	49	48	2	IPR002172
Domain	LDLa	SPINT1 TMPRSS6	7.04e-03	49	48	2	SM00192
Domain	-	ZNF136 ZIC5 YY2 SNAI3 ZNF785 ZNF646	7.56e-03	679	48	6	3.30.160.60
Domain	-	TMPRSS6 ZZEF1	7.90e-03	52	48	2	2.60.120.290
Domain	Znf_C2H2/integrase_DNA-bd	ZNF136 ZIC5 YY2 SNAI3 ZNF785 ZNF646	8.38e-03	694	48	6	IPR013087
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZFP36L2 OBSCN UNKL ICE1 RHOT2 EXTL3 ZZEF1 CNTROB AHDC1 RIC1 RYR1 GGA3 HR NOD2	4.25e-10	1105	51	14	35748872
Pubmed	Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function.	HR VEGFA	2.11e-06	2	51	2	17003502
Pubmed	Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia: implications for the pathogenesis of psoriasis.	HR VEGFA	2.11e-06	2	51	2	18688025
Pubmed	Killer-cell immunoglobulin-like receptors and falciparum malaria in southwest Nigeria.	KIR2DS3 KIR2DS5	6.32e-06	3	51	2	24929143
Pubmed	A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.	KIR2DS3 KIR2DS5	6.32e-06	3	51	2	8765026
Pubmed	Activating killer immunoglobulin-like receptor incompatibilities enhance graft-versus-host disease and affect survival after allogeneic hematopoietic stem cell transplantation.	KIR2DS3 KIR2DS5	6.32e-06	3	51	2	19500138
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CNOT6 IFT140 HPS4 ICE1 ZZEF1 GGA3 ZNF646	1.17e-05	529	51	7	14621295
Pubmed	ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production.	ZFP36L2 VEGFA	1.26e-05	4	51	2	20166898
Pubmed	A role for KIR gene variants other than KIR2DS1 in conferring susceptibility to psoriasis.	KIR2DS3 KIR2DS5	1.26e-05	4	51	2	16829306
Pubmed	In contrast to other stimulatory natural killer cell immunoglobulin-like receptor loci, several KIR2DS5 alleles predominate in African Americans.	KIR2DS3 KIR2DS5	2.10e-05	5	51	2	19410616
Pubmed	Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b.	ZFP36L2 VEGFA	2.10e-05	5	51	2	15467755
Pubmed	NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.	KIR2DS3 KIR2DS5	5.87e-05	8	51	2	18681957
Pubmed	Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.	KIR2DS3 KIR2DS5	7.54e-05	9	51	2	7749980
Pubmed	Alternatively spliced forms of human killer inhibitory receptors.	KIR2DS3 KIR2DS5	7.54e-05	9	51	2	8662091
Pubmed	Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.	KIR2DS3 KIR2DS5	9.42e-05	10	51	2	21206914
Pubmed	Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.	KIR2DS3 KIR2DS5	9.42e-05	10	51	2	12559621
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MCPH1 OBSCN DNAH2 ICE1 ZZEF1 SNAI3 RYR1	9.52e-05	736	51	7	29676528
Pubmed	Natural killer cells and immune surveillance.	KIR2DS3 KIR2DS5	1.15e-04	11	51	2	18830515
Pubmed	[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].	KIR2DS3 KIR2DS5	1.15e-04	11	51	2	19664392
Pubmed	Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.	KIR2DS3 KIR2DS5	1.38e-04	12	51	2	20371502
Pubmed	Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.	KIR2DS3 KIR2DS5	1.38e-04	12	51	2	19181658
Pubmed	[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].	KIR2DS3 KIR2DS5	1.38e-04	12	51	2	20137308
Pubmed	Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.	KIR2DS3 KIR2DS5	1.38e-04	12	51	2	19936734
Pubmed	[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].	KIR2DS3 KIR2DS5	1.63e-04	13	51	2	18687225
Pubmed	KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.	KIR2DS3 KIR2DS5	1.63e-04	13	51	2	19934297
Pubmed	Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.	KIR2DS3 KIR2DS5	1.63e-04	13	51	2	19120281
Pubmed	Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.	IFT140 UNKL RHOT2	1.79e-04	74	51	3	11157797
Pubmed	Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.	KIR2DS3 KIR2DS5	1.90e-04	14	51	2	19875891
Pubmed	Multiple sclerosis associates with LILRA3 deletion in Spanish patients.	KIR2DS3 KIR2DS5	1.90e-04	14	51	2	19421224
Pubmed	Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.	KIR2DS3 KIR2DS5	1.90e-04	14	51	2	15896204
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	20082646
Pubmed	Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	19926642
Pubmed	Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	19850842
Pubmed	Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	20207982
Pubmed	Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	19493232
Pubmed	[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	20356536
Pubmed	Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	20643584
Pubmed	KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	17498266
Pubmed	Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.	KIR2DS3 KIR2DS5	2.19e-04	15	51	2	19326408
Pubmed	Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	19897003
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	19000141
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	20670355
Pubmed	Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	19527230
Pubmed	Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	20652381
Pubmed	Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	18668235
Pubmed	Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	19279038
Pubmed	No association of KIR genes with Behcet's disease.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	17868255
Pubmed	A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	18643961
Pubmed	Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	19309280
Pubmed	Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote.	CNOT6 VEGFA	2.50e-04	16	51	2	16880268
Pubmed	Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	20331834
Pubmed	[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	16403292
Pubmed	HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.	KIR2DS3 KIR2DS5	2.50e-04	16	51	2	20210919
Pubmed	Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	19032228
Pubmed	The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	20173784
Pubmed	The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	20173792
Pubmed	Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	20483367
Pubmed	[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	19968064
Pubmed	Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice.	SPINT1 VEGFA	2.83e-04	17	51	2	17673674
Pubmed	[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	19218127
Pubmed	KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	19169284
Pubmed	Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	20878400
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	20650299
Pubmed	Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	19450876
Pubmed	Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.	KIR2DS3 KIR2DS5	2.83e-04	17	51	2	19761533
Pubmed	Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.	KIR2DS3 KIR2DS5	3.18e-04	18	51	2	19630074
Pubmed	Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.	KIR2DS3 KIR2DS5	3.18e-04	18	51	2	20519398
Pubmed	Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.	KIR2DS3 KIR2DS5	3.18e-04	18	51	2	20200544
Pubmed	Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.	KIR2DS3 KIR2DS5	3.18e-04	18	51	2	19046302
Pubmed	Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.	KIR2DS3 KIR2DS5	3.18e-04	18	51	2	19846535
Pubmed	Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.	KIR2DS3 KIR2DS5	3.18e-04	18	51	2	20580654
Pubmed	Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.	KIR2DS3 KIR2DS5	3.18e-04	18	51	2	20210918
Pubmed	KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.	KIR2DS3 KIR2DS5	3.55e-04	19	51	2	18571006
Pubmed	Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.	KIR2DS3 KIR2DS5	3.55e-04	19	51	2	18778326
Pubmed	Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.	KIR2DS3 KIR2DS5	3.55e-04	19	51	2	20600442
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.	KIR2DS3 KIR2DS5	3.55e-04	19	51	2	18848853
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ZNF136 ZIC5 OBSCN USP35 CNTROB AHDC1 ZNF785 VEGFA	3.63e-04	1215	51	8	15146197
Pubmed	Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.	KIR2DS3 KIR2DS5	3.94e-04	20	51	2	20193031
Pubmed	HLA and KIR frequencies in Sicilian Centenarians.	KIR2DS3 KIR2DS5	3.94e-04	20	51	2	20426625
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	CNOT6 IFT140 MCPH1 FRMD7 DLG2 RHOT2 CFAP61 CRB2	4.20e-04	1242	51	8	30973865
Pubmed	Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.	KIR2DS3 KIR2DS5	4.35e-04	21	51	2	19861144
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	CDH9 RYR1	4.78e-04	22	51	2	26494785
Pubmed	Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).	KIR2DS3 KIR2DS5	4.78e-04	22	51	2	20492596
Pubmed	Immunogenetic characteristics of patients with autoimmune gastritis.	KIR2DS3 KIR2DS5	8.35e-04	29	51	2	20082482
Pubmed	Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.	KIR2DS3 KIR2DS5	1.22e-03	35	51	2	19683555
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	DDX17 CNTROB AHDC1 VEGFA	1.43e-03	332	51	4	37433992
Interaction	TOP3B interactions	ZFP36L2 OBSCN UNKL ICE1 RHOT2 EXTL3 ZZEF1 CNTROB AHDC1 RIC1 RYR1 GGA3 HR NOD2	8.76e-06	1470	50	14	int:TOP3B
Cytoband	11q14.1	DLG2 USP35	1.01e-03	42	51	2	11q14.1
Cytoband	15q15.1	JMJD7 SPINT1	1.27e-03	47	51	2	15q15.1
Cytoband	16p13.3	IFT140 UNKL RHOT2	2.56e-03	244	51	3	16p13.3
Cytoband	19q13.4	KIR2DS3 KIR2DS5	3.53e-03	79	51	2	19q13.4
Cytoband	Ensembl 112 genes in cytogenetic band chr16q12	NKD1 NOD2	5.92e-03	103	51	2	chr16q12
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	DNAH2 ZZEF1 CNTROB	6.76e-03	346	51	3	chr17p13
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DS3 KIR2DS5	5.78e-04	18	36	2	620
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF136 ZIC5 YY2 SNAI3 ZNF785 ZNF646	2.70e-03	718	36	6	28
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	DLG2 PPP1R36 RYR1	5.53e-03	181	36	3	694
GeneFamily	EF-hand domain containing	NKD1 RHOT2 ZZEF1	9.33e-03	219	36	3	863
Coexpression	DESCARTES_MAIN_FETAL_CCL19_CCL21_POSITIVE_CELLS	WDR97 ZFP36L2 YY2 TRIM47 AHDC1 VEGFA	1.63e-05	278	51	6	M40127
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ZFP36L2 DLG2 TRIM47 CRB2 VEGFA	2.62e-06	199	49	5	f4fdf94c561dca35bb17766d908c5030655f43eb
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ZFP36L2 DLG2 TRIM47 CRB2 VEGFA	2.62e-06	199	49	5	c0fe99ed906d0eb99cccdab9a1fa32c17b3542e7
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SNAI3 RYR1 VEGFA NOD2	2.81e-05	159	49	4	6115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SNAI3 RYR1 VEGFA NOD2	2.88e-05	160	49	4	a90eb621481fd07a821495db07d1032e109fd386
ToppCell	droplet-Thymus-nan-21m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPINT1 OBSCN PPP1R36 HR	2.95e-05	161	49	4	441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCell	COVID-19_Mild-PLT_2\|World / Disease Group and Platelet Clusters	SLCO4C1 MCPH1 USP35 RIC1	3.57e-05	169	49	4	6abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	BSPRY AHDC1 ZNF785 ZNF646	3.91e-05	173	49	4	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	COVID-19_Mild-PLT_2\|COVID-19_Mild / Disease Group and Platelet Clusters	SLCO4C1 MCPH1 USP35 RIC1	3.91e-05	173	49	4	d11705e56b6b21eec963ea224717f27680c781ed
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NKD1 DLG2 CRB2 VEGFA	4.86e-05	183	49	4	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NKD1 DLG2 CRB2 VEGFA	4.86e-05	183	49	4	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NKD1 DLG2 CRB2 VEGFA	4.97e-05	184	49	4	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	WDR97 SPINT1 BSPRY ZNF785	5.07e-05	185	49	4	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	E17.5-Epithelial-alveolar_epithelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NKD1 SPINT1 BSPRY VEGFA	5.18e-05	186	49	4	a7a2ef8392a045a62fa4d0983577711d5d397dc4
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Proliferative_AT2_Progenitor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	SLCO4C1 SPINT1 TMPRSS6 BSPRY	5.29e-05	187	49	4	e986901f5a1e09cbc9ba37e3c62845ff90ceda95
ToppCell	E17.5-Epithelial\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NKD1 SPINT1 BSPRY VEGFA	5.29e-05	187	49	4	fdabe716ce67f2eede90548198cbe20bbf693570
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TOR1AIP2 SND1-IT1 ZZEF1 VEGFA	5.29e-05	187	49	4	4527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	SLCO4C1 SPINT1 TMPRSS6 BSPRY	5.98e-05	193	49	4	c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCell	E16.5-samps-Epithelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	SLCO4C1 SPINT1 TMPRSS6 BSPRY	5.98e-05	193	49	4	1cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	SPINT1 TMPRSS6 TRIM47 RYR1	6.10e-05	194	49	4	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TMPRSS6 BSPRY SNAI3	8.39e-05	77	49	3	10969743351c49a1d6d8ae1ef93098e7786ca3fe
Drug	Atractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A	IFT140 DDX17 BSPRY PGPEP1 EXTL3 VEGFA	4.92e-06	196	51	6	3435_UP
Drug	1c88	MCPH1 KIR2DS3 KIR2DS5 HR NOD2	9.18e-06	126	51	5	CID000444766
Disease	Kunitz-type protease inhibitor 1 measurement	GJA9 SPINT1	8.88e-05	9	47	2	EFO_0008199
Disease	alcohol use disorder (implicated_via_orthology)	DDX17 JMJD7 RYR1 HR	2.64e-04	195	47	4	DOID:1574 (implicated_via_orthology)
Disease	proteinuria (implicated_via_orthology)	HR VEGFA	1.05e-03	30	47	2	DOID:576 (implicated_via_orthology)
Disease	colorectal adenoma	DLG2 NOD2	1.27e-03	33	47	2	EFO_0005406

Protein segments in the cluster

Peptide	Gene	Start	Entry
PFHGLCFPHPDDVLE	CFAP61	261	Q8NHU2
DGKHFPPLAHPPTVF	AHDC1	1376	Q5TGY3
PHRKPQGVDPASFHF	NKD1	306	Q969G9
PLFPRDHRKPHSFLS	RIC1	751	Q4ADV7
TFEKACHPFLLGPPL	TOR1AIP2	81	Q9H496
EPFELSHHFPAAPLC	MCPH1	726	Q8NEM0
RLDGCHLPFFPLPLD	CRB2	771	Q5IJ48
GEKHFLFHPPSDRPF	JMJD7	191	P0C870
EFRPLGPCPALSHKA	FRMD7	606	Q6ZUT3
HFAFLHVPVPDGRAP	HPS4	386	Q9NQG7
HGCFSLAERPSPPKA	CCDC120	231	Q96HB5
PQPCPRRGFHLFQEH	HR	851	O43593
HGRSAFVHVPPLGKP	PGPEP1	161	Q9NXJ5
PHEGFRRKPSLLAHP	KIR2DS3	21	Q14952
FHFAKECPPGRPDVL	GGA3	611	Q9NZ52
PHEGFRRKPSLLAHP	KIR2DS5	21	Q14953
LFHFPGRHLPLDEPA	OBSCN	7396	Q5VST9
FCAATPKHALPVPGR	ICE1	1716	Q9Y2F5
LCAHHVSFPGPLFPV	BSPRY	376	Q5W0U4
FHLEPLFKCHGHPCP	GJA9	181	P57773
PCSHVGHVFPKRAPY	GALNT4	356	Q8N4A0
CAPGPFHLFPHTPFD	EXTL3	606	O43909
FPDKFGSCVPHTTRP	DLG2	701	Q15700
RGGDVCPKPVFAFHH	DDX17	161	Q92841
FHHLCPSKRPPIFGD	DNAH2	2681	Q9P225
LRPPHHFSPPCFVAA	RYR1	1771	P21817
NTHPDPRFLHLGPFK	CDH9	351	Q9ULB4
HLTHCIFRLPPPGED	IFT140	151	Q96RY7
GCPHPLIPSDHFSLF	CNOT6	521	Q9ULM6
LGAFHPDHRAERPFP	CNTROB	671	Q8N137
KVHHLFLEGFPCSPR	SND1-IT1	61	Q9HBX3
FCPAHLGPHERSPAL	TRIM47	151	Q96LD4
GPSPAEFCRKHRLPA	RHOT2	536	Q8IXI1
PRAPGGFECFHCHKP	SNAI3	146	Q3KNW1
VCGKPFHSLSPFRIH	ZNF136	396	P52737
RKHFHSIPPAAPGEA	NOD2	716	Q9HC29
PFSCFPKHLPGTAEI	SLCO4C1	331	Q6ZQN7
RIHFPSDKGHCVDLP	SPINT1	381	O43278
PVPPHHVLRCFAAYG	WDR97	256	A6NE52
FFPATVQPHKHCLRP	WDR97	1026	A6NE52
GFHPHTKEPRLFSIC	STAMBPL1	406	Q96FJ0
HPRCVPDGPHRLLFC	USP35	151	Q9P2H5
HLRIHTGDKPFVCPF	YY2	331	O15391
PREGPFTCPHCPRHF	ZNF646	1756	O15015
GEPRCLFNPHTLHPL	PPP1R36	366	Q96LQ0
LHCAFAHGPLDLRPP	UNKL	136	Q9H9P5
SLGQPHCFHPPFILF	ZZEF1	1601	O43149
PHPCGPCSERRKHLF	VEGFA	181	P15692
FPREPRPKLHHSLSF	ZFP36L2	246	P47974
RHPRQDLCGEHPSFP	nan	81	Q96M66
GGKDPPVHFRHFPDI	ZNF785	386	A8K8V0
PVCLPARSHFFEPGL	TMPRSS6	686	Q8IU80
HIRVHTGEKPFPCPF	ZIC5	481	Q96T25