Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.51e-08361647GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.51e-08361647GO:0015662
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

MRS2 SLC4A3 ABCC6 SLC22A6 SLC8A2 KCNA1 SLC10A1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 SLC45A3 KCND3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.76e-0775816422GO:0015318
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA4 ABCC6 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.88e-071091649GO:0042626
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

7.46e-07621647GO:0019829
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCA4 MRS2 SPNS3 SLC4A3 ABCC6 SLC52A3 SLC22A6 SLC8A2 KCNA1 SLC10A1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 SLC45A3 KCND3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A DISP1 SLC27A5

1.22e-06118016427GO:0022857
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2A1 ATP2A2 ATP2A3 ATP2B3

1.38e-06111644GO:0005388
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

MRS2 SLC8A2 KCNA1 SLC10A1 KCNA6 KCNA10 KCND1 KCND3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.51e-0646516416GO:0046873
GeneOntologyMolecularFunctiontransporter activity

ABCA4 MRS2 SPNS3 SLC4A3 ABCC6 SLC52A3 SLC22A6 SLC8A2 KCNA1 SLC10A1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 SLC45A3 KCND3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A DISP1 SLC27A5

6.37e-06128916427GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

MRS2 SLC4A3 SLC8A2 KCNA1 SLC10A1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 SLC45A3 KCND3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

8.36e-0679316420GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

MRS2 SLC8A2 KCNA1 SLC10A1 KCNA6 KCNA10 KCND1 SLC45A3 KCND3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.67e-0562716417GO:0022890
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA4 ABCC6 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.68e-051781649GO:0015399
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

MRS2 SLC8A2 KCNA1 SLC10A1 KCNA6 KCNA10 KCND1 SLC45A3 KCND3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

3.44e-0566416417GO:0008324
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC4A3 SLC8A2 SLC10A1 SLC45A3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

4.05e-0530116411GO:0022853
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA4 SLC4A3 ABCC6 SLC22A6 SLC8A2 SLC10A1 SLC45A3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

4.10e-0547716414GO:0022804
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A2 ATP4A

6.26e-05101643GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A2 ATP4A

6.26e-05101643GO:0005391
GeneOntologyMolecularFunctionthreonine deaminase activity

SDSL SDS

6.70e-0521642GO:0004794
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNA1 KCNA6 KCNA10 KCND1 KCND3 ATP1A1 ATP1A2 ATP4A

7.31e-051671648GO:0015079
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A2 ATP4A

8.55e-05111643GO:0008556
GeneOntologyMolecularFunctionpotassium ion binding

ATP1A1 ATP1A2 ATP4A

1.85e-04141643GO:0030955
GeneOntologyMolecularFunctionL-serine ammonia-lyase activity

SDSL SDS

2.00e-0431642GO:0003941
GeneOntologyMolecularFunctioncalcium-dependent ATPase activity

ATP2A1 ATP2A3

3.98e-0441642GO:0030899
GeneOntologyMolecularFunctionA-type (transient outward) potassium channel activity

KCND1 KCND3

3.98e-0441642GO:0005250
GeneOntologyMolecularFunctionATP-dependent activity

ABCA4 SMARCAL1 SRCAP ABCC6 DDX11 STARD9 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A SLC27A5

5.58e-0461416414GO:0140657
GeneOntologyMolecularFunctionammonia-lyase activity

SDSL SDS

6.60e-0451642GO:0016841
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNA1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 KCND3

7.79e-041821647GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNA1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 KCND3

8.31e-041841647GO:0022832
GeneOntologyMolecularFunctioncoenzyme A diphosphatase activity

NUDT7 NUDT8

9.84e-0461642GO:0010945
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA4 SRCAP ABCC6 DDX11 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.08e-0344116411GO:0016887
GeneOntologyMolecularFunctionalkali metal ion binding

ATP1A1 ATP1A2 ATP4A

1.23e-03261643GO:0031420
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A2

1.37e-0371642GO:1990239
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNA1 KCNA6 KCNA10

1.53e-03281643GO:0005251
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNA1 KCNA6 KCNA10 KCND1 KCND3

1.54e-031021645GO:0005249
GeneOntologyBiologicalProcesscardiac conduction

SLC4A3 SLC8A2 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

9.40e-081001629GO:0061337
GeneOntologyBiologicalProcessregulation of cardiac conduction

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.86e-06291625GO:1903779
GeneOntologyBiologicalProcessaction potential

SLC4A3 SLC8A2 KCNA1 KCNA6 KCNA10 KCND1 KCND3 ATP1A1 ATP1A2 ATP2A2

4.42e-0620116210GO:0001508
GeneOntologyBiologicalProcesspropionyl-CoA catabolic process

NUDT7 NUDT8

6.13e-0521622GO:1902859
GeneOntologyBiologicalProcesscalcium ion transport from cytosol to endoplasmic reticulum

ATP2A2 ATP2A3

6.13e-0521622GO:1903515
GeneOntologyBiologicalProcessestablishment or maintenance of transmembrane electrochemical gradient

ATP1A1 ATP1A2 ATP4A

7.49e-05111623GO:0010248
GeneOntologyBiologicalProcessexport across plasma membrane

SLC8A2 KCND3 ATP1A1 ATP1A2 ATP2B3 ATP4A

8.22e-05911626GO:0140115
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

IREB2 MINPP1 SLC4A3 ABCC6 DMXL1 SLC8A2 KCNA1 BOK TMEM9 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.42e-0470516216GO:0055080
GeneOntologyBiologicalProcessregulation of heart contraction

SLC4A3 SLC8A2 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

1.60e-042491629GO:0008016
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

IREB2 MINPP1 SLC4A3 ABCC6 DMXL1 SLC8A2 KCNA1 BOK TMEM9 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.73e-0471716216GO:0050801
GeneOntologyBiologicalProcessregulation of platelet formation

MPL CSF1R

1.83e-0431622GO:1905219
GeneOntologyBiologicalProcesspositive regulation of endoplasmic reticulum calcium ion concentration

ATP2A1 ATP2A2

1.83e-0431622GO:0032470
GeneOntologyBiologicalProcessbutyryl-CoA catabolic process

NUDT7 NUDT8

1.83e-0431622GO:0044580
GeneOntologyBiologicalProcessacetyl-CoA catabolic process

NUDT7 NUDT8

1.83e-0431622GO:0046356
GeneOntologyBiologicalProcessisoleucine biosynthetic process

SDSL SDS

1.83e-0431622GO:0009097
GeneOntologyBiologicalProcessintracellular potassium ion homeostasis

ATP1A1 ATP1A2 ATP4A

2.98e-04171623GO:0030007
GeneOntologyBiologicalProcesssodium ion export across plasma membrane

ATP1A1 ATP1A2 ATP4A

2.98e-04171623GO:0036376
GeneOntologyBiologicalProcessrelaxation of muscle

ATP1A1 ATP1A2 ATP2A1 ATP2A2

3.25e-04421624GO:0090075
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

IREB2 MINPP1 SLC4A3 DMXL1 SLC8A2 BOK TMEM9 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

3.41e-0461116214GO:0030003
GeneOntologyBiologicalProcessregulation of cardiac muscle cell contraction

ATP1A1 ATP1A2 ATP2A1 ATP2A2

3.56e-04431624GO:0086004
GeneOntologyBiologicalProcessmedium-chain fatty-acyl-CoA catabolic process

NUDT7 NUDT8

3.64e-0441622GO:0036114
GeneOntologyBiologicalProcesspropionyl-CoA metabolic process

NUDT7 NUDT8

3.64e-0441622GO:1902858
GeneOntologyBiologicalProcessmalonyl-CoA catabolic process

NUDT7 NUDT8

3.64e-0441622GO:2001294
GeneOntologyCellularComponentplatelet dense tubular network membrane

ATP2A1 ATP2A2 ATP2A3

3.92e-0591653GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ATP2A1 ATP2A2 ATP2A3

7.61e-05111653GO:0031094
GeneOntologyCellularComponentcaveola

HDAC6 TGFBR1 SLC22A6 KCND3 ATP1A1 ATP1A2

2.52e-041111656GO:0005901
GeneOntologyCellularComponentbasal plasma membrane

ABCC6 LEPR TGFBR1 SLC22A6 SLC8A2 SLC10A1 CLCNKA SCRIB ATP1A1 SLC27A5

5.25e-0435416510GO:0009925
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP1A1 ATP1A2 ATP2A2 ATP4A

6.01e-04491654GO:0090533
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNA1 KCNA6 KCNA10 KCND1 KCND3

7.76e-04911655GO:0008076
GeneOntologyCellularComponentbasal part of cell

ABCC6 LEPR TGFBR1 SLC22A6 SLC8A2 SLC10A1 CLCNKA SCRIB ATP1A1 SLC27A5

8.68e-0437816510GO:0045178
GeneOntologyCellularComponentcell-cell contact zone

SCRIB ATP1A1 ATP1A2 ATP2A2 PCDH9

8.99e-04941655GO:0044291
GeneOntologyCellularComponentprocentriole replication complex

CEP192 STIL

9.10e-0461652GO:0120099
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP1A1 ATP1A2 ATP2A2 ATP4A

9.33e-04551654GO:0098533
GeneOntologyCellularComponenttransmembrane transporter complex

KCNA1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP4A

9.40e-0452316512GO:1902495
GeneOntologyCellularComponentneuronal cell body

MPL HDAC6 KALRN IREB2 ALS2 SLC8A2 KCNA1 CSF1R HMCN2 KCND1 KCND3 NPTXR KNDC1 ATP1A2 KLHL14 SORL1

9.65e-0483516516GO:0043025
GeneOntologyCellularComponentbasolateral plasma membrane

ABCC6 LEPR TGFBR1 SLC22A6 SLC8A2 SLC10A1 CLCNKA SCRIB ATP1A1

1.03e-033201659GO:0016323
GeneOntologyCellularComponentplasma membrane raft

HDAC6 TGFBR1 SLC22A6 KCND3 ATP1A1 ATP1A2

1.12e-031471656GO:0044853
GeneOntologyCellularComponentcell surface

MPL LRFN1 LAG3 ADGRV1 SLC4A3 LEPR SIRPG TGFBR1 DUOX1 KCNA1 CSF1R CD8B CD8B2 PTPRJ ATP1A2 TNS1 PLXNB3 SORL1 IL9R

1.26e-03111116519GO:0009986
GeneOntologyCellularComponentpotassium channel complex

KCNA1 KCNA6 KCNA10 KCND1 KCND3

1.41e-031041655GO:0034705
GeneOntologyCellularComponenttransporter complex

KCNA1 KCNA6 KCNA10 CLCNKA CLCNKB KCND1 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP4A

1.44e-0355016512GO:1990351
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.91e-11161587IPR023298
Domain-

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.91e-111615871.20.1110.10
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

4.91e-11171587IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

4.91e-11171587PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

7.98e-11181587PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

7.98e-11181587SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.26e-10191587IPR004014
DomainATPase_P-typ_cyto_domN

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.50e-08351587IPR023299
DomainATPase_P-typ_P_site

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.84e-08361587IPR018303
DomainP_typ_ATPase

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.84e-08361587IPR001757
DomainATPASE_E1_E2

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

1.84e-08361587PS00154
DomainATPase_P-typ_transduc_dom_A

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.26e-08371587IPR008250
DomainE1-E2_ATPase

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.26e-08371587PF00122
Domain-

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP4A

2.52e-073215863.40.1110.10
Domain-

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP4A

2.52e-073215862.70.150.10
DomainP-type_ATPase_IIA

ATP2A1 ATP2A2 ATP2A3

5.94e-0731583IPR005782
DomainHydrolase_3

ATP2A1 ATP2A2 ATP2A3 ATP2B3

9.95e-07101584PF08282
DomainK_chnl_volt-dep_Kv

KCNA1 KCNA6 KCNA10 KCND1 KCND3

2.82e-06271585IPR003968
DomainHAD-like_dom

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

4.72e-06791587IPR023214
DomainIg_V-set

LAG3 IGSF11 OPCML SIRPG CSF1R CD8B HMCN1 SIGLEC6 SIGLEC1 IGLON5

7.66e-0619915810IPR013106
DomainVG_K_chnl

KCNA1 KCNA6 KCNA10 KCND1 KCND3

7.97e-06331585IPR028325
DomainIg-like_fold

MPL LRFN1 KALRN LAG3 IGSF11 LEPR OPCML SIRPG CSF1R HMCN2 CD8B HMCN1 PTPRJ SIGLEC6 SIGLEC1 IGLON5 PLXNB3 SORL1 IL9R

8.50e-0670615819IPR013783
DomainP-type_ATPase_IIC

ATP1A1 ATP1A2 ATP4A

1.17e-0561583IPR005775
Domain-

MPL LRFN1 KALRN LAG3 IGSF11 LEPR OPCML SIRPG CSF1R CD8B HMCN1 PTPRJ SIGLEC6 SIGLEC1 IGLON5 PLXNB3 SORL1 IL9R

1.33e-05663158182.60.40.10
DomainV-set

LAG3 IGSF11 OPCML SIRPG CSF1R CD8B SIGLEC6 SIGLEC1 IGLON5

2.74e-051841589PF07686
DomainK_chnl_volt-dep_Kv1

KCNA1 KCNA6 KCNA10

3.22e-0581583IPR003972
DomainIGc2

LRFN1 KALRN IGSF11 OPCML CSF1R HMCN2 HMCN1 SIGLEC6 SIGLEC1 IGLON5

3.23e-0523515810SM00408
DomainIg_sub2

LRFN1 KALRN IGSF11 OPCML CSF1R HMCN2 HMCN1 SIGLEC6 SIGLEC1 IGLON5

3.23e-0523515810IPR003598
DomainIg_I-set

LRFN1 KALRN IGSF11 OPCML HMCN2 HMCN1 SIGLEC6 SIGLEC1 IGLON5

3.52e-051901589IPR013098
DomainI-set

LRFN1 KALRN IGSF11 OPCML HMCN2 HMCN1 SIGLEC6 SIGLEC1 IGLON5

3.52e-051901589PF07679
DomainIG

LRFN1 KALRN LAG3 IGSF11 OPCML SIRPG CSF1R HMCN2 CD8B HMCN1 SIGLEC6 SIGLEC1 IGLON5

6.20e-0542115813SM00409
DomainIg_sub

LRFN1 KALRN LAG3 IGSF11 OPCML SIRPG CSF1R HMCN2 CD8B HMCN1 SIGLEC6 SIGLEC1 IGLON5

6.20e-0542115813IPR003599
DomainVIT_2

VWA5B2 VWA5B1

7.11e-0521582PF13757
DomainCl_channel-K

CLCNKA CLCNKB

7.11e-0521582IPR002250
DomainIG_LIKE

LRFN1 KALRN LAG3 IGSF11 LEPR OPCML SIRPG CSF1R HMCN2 CD8B HMCN1 SIGLEC6 SIGLEC1 IGLON5

7.57e-0549115814PS50835
DomainBTB_2

KCNA1 KCNA6 KCNA10 KCND1 KCND3

8.41e-05531585PF02214
DomainT1-type_BTB

KCNA1 KCNA6 KCNA10 KCND1 KCND3

8.41e-05531585IPR003131
DomainIg-like_dom

LRFN1 KALRN LAG3 IGSF11 LEPR OPCML SIRPG CSF1R HMCN2 CD8B HMCN1 SIGLEC6 SIGLEC1 IGLON5

9.78e-0550315814IPR007110
DomainChannel_four-helix_dom

KCNA1 KCNA6 KCNA10 KCND1 KCND3

1.19e-04571585IPR027359
Domain-

KCNA1 KCNA6 KCNA10 KCND1 KCND3

1.19e-045715851.20.120.350
DomainShal-type_N

KCND1 KCND3

2.12e-0431582IPR021645
DomainK_chnl_volt-dep_Kv4_C

KCND1 KCND3

2.12e-0431582IPR024587
DomainDUF3399

KCND1 KCND3

2.12e-0431582PF11879
DomainK_chnl_volt-dep_Kv4

KCND1 KCND3

2.12e-0431582IPR003975
DomainShal-type

KCND1 KCND3

2.12e-0431582PF11601
DomainSer/Thr_deHydtase_PyrdxlP-BS

SDSL SDS

2.12e-0431582IPR000634
DomainDEHYDRATASE_SER_THR

SDSL SDS

2.12e-0431582PS00165
Domainig

LAG3 OPCML SIRPG CSF1R HMCN1 SIGLEC6 SIGLEC1 IGLON5

2.17e-041901588PF00047
DomainImmunoglobulin

LAG3 OPCML SIRPG CSF1R HMCN1 SIGLEC6 SIGLEC1 IGLON5

2.17e-041901588IPR013151
DomainG2F

HMCN2 HMCN1

4.22e-0441582PF07474
DomainNIDOGEN_G2

HMCN2 HMCN1

4.22e-0441582PS50993
DomainGFP

HMCN2 HMCN1

4.22e-0441582IPR009017
DomainG2_nidogen/fibulin_G2F

HMCN2 HMCN1

4.22e-0441582IPR006605
Domain-

RAG2 KLHL11 MEGF8 KLHL14

7.18e-044815842.120.10.80
DomainBTB

KLHL11 KCNA1 KCNA6 KCNA10 KCND1 KCND3 KLHL14

8.64e-041801587SM00225
DomainBTB/POZ_dom

KLHL11 KCNA1 KCNA6 KCNA10 KCND1 KCND3 KLHL14

1.01e-031851587IPR000210
DomainSKP1/BTB/POZ

KLHL11 KCNA1 KCNA6 KCNA10 KCND1 KCND3 KLHL14

1.15e-031891587IPR011333
DomainKelch-typ_b-propeller

RAG2 KLHL11 MEGF8 KLHL14

1.20e-03551584IPR015915
DomainTrpB-like_PLP-dep

SDSL SDS

1.45e-0371582IPR001926
DomainPALP

SDSL SDS

1.45e-0371582PF00291
DomainFN3

MPL LRFN1 KALRN LEPR PTPRJ SORL1 IL9R

1.54e-031991587PS50853
DomainGal_Oxase/kelch_b-propeller

RAG2 KLHL11 MEGF8 KLHL14

1.56e-03591584IPR011043
DomainVWA_3

VWA5B2 VWA5B1

1.93e-0381582PF13768
DomainCalx_beta

ADGRV1 SLC8A2

1.93e-0381582SM00237
DomainDH_1

KALRN ALS2 PLEKHG5 ARHGEF10L

1.99e-03631584PS00741
DomainFN3_dom

MPL LRFN1 KALRN LEPR PTPRJ SORL1 IL9R

2.04e-032091587IPR003961
DomainCalx_beta

ADGRV1 SLC8A2

2.46e-0391582IPR003644
DomainCl-channel_core

CLCNKA CLCNKB

2.46e-0391582IPR014743
Domain-

CLCNKA CLCNKB

2.46e-03915821.10.3080.10
DomainVoltage_CLC

CLCNKA CLCNKB

2.46e-0391582PF00654
DomainCl-channel_volt-gated

CLCNKA CLCNKB

2.46e-0391582IPR001807
DomainCalx-beta

ADGRV1 SLC8A2

2.46e-0391582PF03160
DomainHempt_rcpt_S_F1_CS

LEPR IL9R

2.46e-0391582IPR003531
DomainIon_trans_dom

KCNA1 KCNA6 KCNA10 KCND1 KCND3

2.85e-031141585IPR005821
DomainIon_trans

KCNA1 KCNA6 KCNA10 KCND1 KCND3

2.85e-031141585PF00520
DomainRhoGEF

KALRN ALS2 PLEKHG5 ARHGEF10L

2.93e-03701584PF00621
DomainDH_2

KALRN ALS2 PLEKHG5 ARHGEF10L

2.93e-03701584PS50010
DomainAn_peroxidase

EPX DUOX1

3.06e-03101582PF03098
DomainHaem_peroxidase_animal

EPX DUOX1

3.06e-03101582IPR019791
DomainVIT

VWA5B2 VWA5B1

3.06e-03101582PS51468
DomainVIT

VWA5B2 VWA5B1

3.06e-03101582IPR013694
DomainHaem_peroxidase

EPX DUOX1

3.06e-03101582IPR010255
DomainPEROXIDASE_3

EPX DUOX1

3.06e-03101582PS50292
Domain-

EPX DUOX1

3.06e-031015821.10.640.10
Domain-

KALRN ALS2 PLEKHG5 ARHGEF10L

3.09e-037115841.20.900.10
DomainDH-domain

KALRN ALS2 PLEKHG5 ARHGEF10L

3.09e-03711584IPR000219
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

3.66e-08121245M27326
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

9.12e-08141245MM15052
PathwayREACTOME_CARDIAC_CONDUCTION

SLC8A2 KCND1 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.95e-071031249MM15196
PathwayREACTOME_ION_HOMEOSTASIS

SLC8A2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

4.32e-07541247M27460
PathwayREACTOME_ION_HOMEOSTASIS

SLC8A2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

4.32e-07541247MM15202
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

4.91e-07551247M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

6.31e-07571247MM15643
PathwayREACTOME_CARDIAC_CONDUCTION

SLC8A2 KCND1 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.12e-061301249M27454
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

3.36e-06271245MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

4.06e-06281245M924
PathwayREACTOME_MUSCLE_CONTRACTION

SLC8A2 KCND1 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

1.49e-051651249MM15026
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCNKA CLCNKB ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.49e-051761249MM15718
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA4 MRS2 IREB2 SLC4A3 ABCC6 SLC22A6 SLC8A2 CLCNKA CLCNKB SLC45A3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

2.75e-0568112418MM14985
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNA6 KCNA10 KCND1 KCND3

2.82e-05411245MM14546
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCNKA CLCNKB ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

3.39e-051831249M997
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNA6 KCNA10 KCND1 KCND3

3.58e-05431245M1056
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA

ATP2A1 ATP2A2 ATP2A3

3.60e-0581243M47955
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA4 MRS2 IREB2 SLC4A3 ABCC6 SLC22A6 SLC8A2 CLCNKA CLCNKB SLC45A3 NIPAL2 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

7.56e-0573612418M27287
PathwayREACTOME_MUSCLE_CONTRACTION

SLC8A2 KCND1 KCND3 ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

7.59e-052031249M5485
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

ATP2A1 ATP2A2 ATP2A3

4.92e-04181243M614
PathwayREACTOME_PLATELET_HOMEOSTASIS

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

5.45e-04761245MM15051
PathwayREACTOME_PLATELET_HOMEOSTASIS

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

9.58e-04861245M916
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ATP4A

7.41e-1129167715071553
Pubmed

Gene knockout studies of Ca2+-transporting ATPases.

ATP2A1 ATP2A2 ATP2A3 ATP2B3

3.54e-088167410951186
Pubmed

The Na(+)-K(+)-ATPase alpha2-subunit isoform modulates contractility in the perinatal mouse diaphragm.

ATP1A1 ATP1A2 ATP2A1 ATP2A2

6.34e-089167415253893
Pubmed

The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.

ATP2A1 ATP2A2 ATP2A3

1.09e-073167316410239
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

KCNA1 KCNA6 CLCNKA CLCNKB KCND1 KCND3 ATP1A2 ATP2A2

3.94e-07139167816985003
Pubmed

Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.

ATP2A1 ATP2A2 ATP2A3

4.33e-074167325110346
Pubmed

The nongastric H+-K+-ATPases: molecular and functional properties.

ATP2A1 ATP2A2 ATP2A3

4.33e-074167310362770
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

ADGRB2 SLC4A3 SIRPG SLC8A2 KCNA1 KCNA6 PTPRJ KCND3 DAAM1 ATP1A1 ATP1A2 ATP2A2

6.85e-074051671238187761
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

SLC8A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

1.06e-0638167530786075
Pubmed

Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.

ATP1A1 ATP1A2 ATP4A

1.08e-065167316870707
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

LRFN1 KALRN IGSF11 OPCML CSF1R HMCN1 SIGLEC1 IGLON5

1.26e-06162167825826454
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNA1 KCNA6 KCNA10 KCND1 KCND3

1.38e-0640167516382104
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 SDSL LRFN1 KALRN SZT2 ADGRB2 CUL9 CEP192 SRCAP BIRC6 PLEKHG5 ARHGEF10L SLC52A3 PNPLA6 MEGF8 SLC45A3 RGL2 ATP2A3 AHNAK2

1.70e-0611051671935748872
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP1A2 ATP4A

2.15e-06616733036582
Pubmed

Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.

KCNA1 KCNA6 KCNA10

2.15e-06616739286706
Pubmed

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

ATP2A1 ATP2A2 ATP2A3

3.75e-067167324786561
Pubmed

Pore size matters for potassium channel conductance.

KCNA1 KCNA6 KCNA10

3.75e-067167327619418
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

ATP2A1 ATP2A2 ATP2A3

5.98e-068167319033399
Pubmed

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.

ATP2A1 ATP2A2 ATP2A3

5.98e-068167327923914
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

FKBP15 SCRIB ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2B3 ATP4A

6.48e-06202167824639526
Pubmed

A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.

ATP2A1 ATP2A2 ATP2A3

8.94e-069167325640239
Pubmed

Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.

KCNA1 KCNA6 KCND1

1.27e-051016731383027
Pubmed

Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.

KCNA1 KCNA6 KCNA10 KCND1

1.46e-053116748034307
Pubmed

Decreased expression of both the alpha1- and alpha2-subunits of the Na-K-ATPase reduces maximal alveolar epithelial fluid clearance.

ATP1A1 ATP1A2

2.29e-052167215781423
Pubmed

Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.

ATP2A1 ATP2A2

2.29e-052167212556521
Pubmed

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

CLCNKA CLCNKB

2.29e-052167227335120
Pubmed

Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.

CLCNKA CLCNKB

2.29e-05216728812470
Pubmed

Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.

CLCNKA CLCNKB

2.29e-052167225919862
Pubmed

Molecular cloning of the mouse ouabain-resistance gene.

ATP1A1 ATP1A2

2.29e-05216726324196
Pubmed

Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

CD8B CD8B2

2.29e-05216723035575
Pubmed

Small-molecule compounds boost genome-editing efficiency of cytosine base editor.

ABCA4 HDAC6

2.29e-052167234329468
Pubmed

Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

CD8B CD8B2

2.29e-05216723498943
Pubmed

Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest.

ATP2A1 ATP2A2

2.29e-052167219644701
Pubmed

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking.

HEATR5A HEATR5B

2.29e-052167238240799
Pubmed

An immunological role for the CD8 beta-chain.

CD8B CD8B2

2.29e-05216721534146
Pubmed

Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles.

ATP2A1 ATP2A2

2.29e-052167214638697
Pubmed

The alpha(1)- and alpha(2)-isoforms of Na-K-ATPase play different roles in skeletal muscle contractility.

ATP1A1 ATP1A2

2.29e-052167211507009
Pubmed

Duality of the murine CD8 compartment.

CD8B CD8B2

2.29e-052167224594598
Pubmed

Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain.

CD8B CD8B2

2.29e-05216727889415
Pubmed

AKXD recombinant inbred strains: models for studying the molecular genetic basis of murine lymphomas.

CD8B CD8B2

2.29e-05216723025647
Pubmed

Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.

CLCNKA CLCNKB

2.29e-052167238069401
Pubmed

Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.

CD8B CD8B2

2.29e-05216722452747
Pubmed

Distinct methylation states of the CD8 beta gene in peripheral T cells and intraepithelial lymphocytes.

CD8B CD8B2

2.29e-05216729233619
Pubmed

Stalk region of beta-chain enhances the coreceptor function of CD8.

CD8B CD8B2

2.29e-052167212847256
Pubmed

Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus latent membrane protein-1.

ATP2A2 ATP2A3

2.29e-052167219650915
Pubmed

Cell-specific role of histone deacetylase 6 in chemotherapy-induced mechanical allodynia and loss of intraepidermal nerve fibers.

RAG2 HDAC6

2.29e-052167231356453
Pubmed

A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.

CLCNKA CLCNKB

2.29e-052167220805576
Pubmed

Sarco/Endoplasmic Reticulum Ca2+ ATPase 2 Activator Ameliorates Endothelial Dysfunction; Insulin Resistance in Diabetic Mice.

LEPR ATP2A2

2.29e-052167235563793
Pubmed

Transcriptional diversity at the duplicated human CD8 beta loci.

CD8B CD8B2

2.29e-05216728436166
Pubmed

Multiple and diverse coexpression, location, and regulation of additional SERCA2 and SERCA3 isoforms in nonfailing and failing human heart.

ATP2A2 ATP2A3

2.29e-052167219962989
Pubmed

Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.

ATP1A1 ATP1A2

2.29e-052167211404365
Pubmed

Mice expressing ouabain-sensitive α1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy.

ATP1A1 ATP1A2

2.29e-052167220952666
Pubmed

Structure and expression of the Lyt-3a gene of C.AKR mice.

CD8B CD8B2

2.29e-05216723169881
Pubmed

Salt wasting and deafness resulting from mutations in two chloride channels.

CLCNKA CLCNKB

2.29e-052167215044642
Pubmed

Esr, a second locus in the house mouse controlling esterase-5.

CD8B CD8B2

2.29e-05216727103930
Pubmed

Expression of alpha isoforms of the Na,K-ATPase in human heart.

ATP1A1 ATP1A2

2.29e-05216728391840
Pubmed

Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.

ATP2A1 ATP2A2

2.29e-052167215718407
Pubmed

The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives.

NUDT7 NUDT8

2.29e-052167211415433
Pubmed

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

CLCNKA CLCNKB

2.29e-05216728041726
Pubmed

A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.

CLCNKA CLCNKB

2.29e-052167218648499
Pubmed

SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.

ATP2A1 ATP2A2

2.29e-052167211402072
Pubmed

Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.

CLCNKA CLCNKB

2.29e-05216728544406
Pubmed

Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes.

CD8B CD8B2

2.29e-05216725558567
Pubmed

Cloning and modeling of CD8 beta in the amphibian ambystoma Mexicanum. Evolutionary conserved structures for interactions with major histocompatibility complex (MHC) class I molecules.

CD8B CD8B2

2.29e-052167212034498
Pubmed

Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.

CLCNKA CLCNKB

2.29e-052167224863058
Pubmed

Regulation of SERCA pumps expression in diabetes.

ATP2A2 ATP2A3

2.29e-052167225270119
Pubmed

Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

CLCNKA CLCNKB

2.29e-05216729916798
Pubmed

Kidney kinetics and chloride ion pumps.

CLCNKA CLCNKB

2.29e-05216729916791
Pubmed

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.

ATP1A1 ATP1A2

2.29e-052167219376809
Pubmed

A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase.

ATP1A1 ATP1A2

2.29e-052167235446892
Pubmed

New molecular determinants controlling the accessibility of ouabain to its binding site in human Na,K-ATPase alpha isoforms.

ATP1A1 ATP1A2

2.29e-052167214742675
Pubmed

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.

HMCN2 HMCN1

2.29e-052167232035013
Pubmed

Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.

CD8B CD8B2

2.29e-05216728108731
Pubmed

Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology.

ATP2A1 ATP2A2

2.29e-052167210603953
Pubmed

Murine Ly-3 restriction fragment length polymorphism and transcript size differences.

CD8B CD8B2

2.29e-05216722576243
Pubmed

Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.

ATP2A1 ATP2A2

2.29e-052167234769190
Pubmed

Histone deacetylase 6 regulates insulin signaling in pancreatic β cells.

HDAC6 LEPR

2.29e-052167233168187
Pubmed

ABCC6/MRP6 mutations: further insight into the molecular pathology of pseudoxanthoma elasticum.

ABCA4 ABCC6

2.29e-052167212673275
Pubmed

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development.

CD8B CD8B2

2.29e-05216729647223
Pubmed

Alterations in genes encoding sarcoplasmic-endoplasmic reticulum Ca(2+) pumps in association with head and neck squamous cell carcinoma.

ATP2A2 ATP2A3

2.29e-052167218295663
Pubmed

DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.

ATP1A1 ATP1A2

2.29e-052167222258333
Pubmed

Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle.

ATP2A1 ATP2A2

2.29e-052167218953100
Pubmed

A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies.

SDSL SDS

2.29e-052167218342636
Pubmed

Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes.

ATP1A1 ATP1A2

2.29e-052167222739122
Pubmed

Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heart.

ATP1A1 ATP1A2

2.29e-052167210360172
Pubmed

Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension.

ATP1A1 ATP2B3

2.29e-052167223416519
Pubmed

SERCA overexpression reduces hydroxyl radical injury in murine myocardium.

ATP2A1 ATP2A2

2.29e-052167216798816
Pubmed

The IB-peptide marker and the Ly-3 surface alloantigen: structural studies of a V kappa-region polymorphism and a T-cell marker determined by linked genes.

CD8B CD8B2

2.29e-0521672408079
Pubmed

Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3.

ATP2A2 ATP2A3

2.29e-052167221885870
Pubmed

Characterization of the mouse CD8 beta chain-encoding gene promoter region.

CD8B CD8B2

2.29e-05216728781121
Pubmed

Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load.

ATP1A1 ATP1A2

2.29e-052167218667729
Pubmed

Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the α1 or α2 Na-K-ATPase ouabain-binding site.

ATP1A1 ATP1A2

2.29e-052167221632957
Pubmed

Expression of the Abca-subfamily of genes in Abcc6-/- mice--upregulation of Abca4.

ABCA4 ABCC6

2.29e-052167221435020
Pubmed

Enzymatic and biochemical properties of a novel human serine dehydratase isoform.

SDSL SDS

2.29e-052167216580895
Pubmed

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.

ATP2A1 ATP2A2

2.29e-052167212975374
Pubmed

Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.

CLCNKA CLCNKB

2.29e-052167211014860
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FKBP15 CUL9 ALS2 HEATR5A CEP192 MEGF8 STARD9 PDE4DIP SCRIB PLXNB3

2.99e-054071671012693553
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

HDAC6 CUL9 NFS1 EPX LEPR PRX MAP4K1 RGL2 ATP2A3

3.29e-05329167917474147
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

MINPP1 LEPR IGFALS CSF1R MEGF8 PTPRJ GUSB PROC

3.67e-05257167816335952
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

NACA ADGRB2 NFS1 KCNA1 KCNA6 PDE4DIP KNDC1

4.96e-05197167736604605
GeneFamilyATPases Ca2+ transporting

ATP2A1 ATP2A2 ATP2A3 ATP2B3

1.72e-07911241209
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRFN1 KALRN SIGLEC16 IGSF11 OPCML HMCN2 HMCN1 SIGLEC6 SIGLEC1

7.07e-071611129593
GeneFamilyPotassium voltage-gated channels

KCNA1 KCNA6 KCNA10 KCND1 KCND3

4.62e-06401125274
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

FKBP15 HDAC6 WDR81 CEP192 KCNA6 SACS TNS1

1.34e-041811127694
GeneFamilyADAM metallopeptidase domain containing|CD molecules

MPL LAG3 LEPR SIRPG CSF1R CD8B PTPRJ SIGLEC6 SIGLEC1 IL9R

1.69e-0439411210471
GeneFamilyI-set domain containing|IgLON cell adhesion molecules

OPCML IGLON5

3.76e-04511221052
GeneFamilyAdenosine receptors|V-set domain containing

SIGLEC16 SIRPG CD8B SIGLEC6 SIGLEC1 IGLON5

5.33e-041631126590
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

SIGLEC16 SIGLEC6 SIGLEC1

6.77e-04281123745
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A2

7.83e-04711221208
GeneFamilyFibulins

HMCN2 HMCN1

1.04e-0381122556
GeneFamilyChloride voltage-gated channels

CLCNKA CLCNKB

1.66e-03101122302
GeneFamilyFibronectin type III domain containing

MPL LRFN1 KALRN PTPRJ SORL1

3.20e-031601125555
GeneFamilyImmunoglobulin like domain containing

LAG3 LEPR CSF1R HMCN2 IGLON5

7.03e-031931125594
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KALRN ALS2 ARHGEF10L

7.98e-03661123722
CoexpressionYOSHIMURA_MAPK8_TARGETS_UP

KALRN SLC4A3 TRBV30 SLC8A2 KCNA1 BOK SLC10A1 IGFALS KCNA6 CLCNKA CLCNKB KCND3 MAP4K1 UGT2A1 DLAT MMS19 ATP2A3 ATP2B3 ATP4A SDS PROC OPLAH IL9R

7.14e-06128116723M1884
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ERMP1 PFKP CLCNKA CLCNKB NIPAL2 ATP1A1 ATP4A SORL1

4.45e-081901679c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ERMP1 PFKP CLCNKA CLCNKB NIPAL2 ATP1A1 ATP4A SORL1

4.45e-0819016795cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT14 HDAC6 WSB2 IGFALS PRSS53 PDE4DIP ATP2A2 ATP2A3

6.74e-0719216785b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Six3-Pvalb_(Thalamic_reticular_nucleus_(TRN))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

BPIFB3 SLC10A1 CLCNKB SPATA25 IL9R

2.38e-06571675ade0457d85acaf87fcbeb6ac0d81525bb4a96950
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Six3-Pvalb_(Thalamic_reticular_nucleus_(TRN))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

BPIFB3 SLC10A1 CLCNKB SPATA25 IL9R

2.38e-065716750e92c8af66bfdf9de6410c82f404b65b1424e09c
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Six3-Pvalb_(Thalamic_reticular_nucleus_(TRN))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

BPIFB3 SLC10A1 CLCNKB SPATA25 IL9R

2.38e-0657167500083b7c710affa6e24ed495ed46ec6fcea8b676
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

SZT2 HEATR5A SPNS3 ARHGEF10L CSF1R MEGF8 SORL1

2.69e-061621677810881210e015c788814e4fe8d7a24c929cf2621
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPL GALNT14 SDSL SPNS3 MAP4K1 KNDC1 ATP2A1

3.16e-06166167716d42eda958b2a6f9d598e9b4b967505dee426ef
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPL GALNT14 SDSL SPNS3 MAP4K1 KNDC1 ATP2A1

3.16e-06166167708d7db4ff1c9c9cea3a36a87b8690838e79d4e0e
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDSL BPIFB3 LAG3 SPNS3 DCLRE1C ATP2A1 ATP4A

3.85e-0617116772dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDSL BPIFB3 LAG3 SPNS3 DCLRE1C ATP2A1 ATP4A

3.85e-0617116772aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCellwk_15-18-Hematologic-Myeloid-Eosinophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MPL ALS2 EPX SLC45A3 SHCBP1L ATP2A1 ATP2A3

4.15e-061731677a85cead231e03945fabbc7762540ad21fe4299df
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A MRS2 KLHL11 PRSS53 PDE4DIP DAAM1 ATP2A3

4.31e-061741677f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAG3 SPNS3 PLEKHG5 SLC45A3 ATP1A2 DISP1 ALOX15B

5.01e-061781677cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL LAG3 SPNS3 PFKP PLEKHG5 SLC45A3 ALOX15B

5.39e-06180167741e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL LAG3 SPNS3 PLEKHG5 SLC45A3 ATP1A2 ALOX15B

5.59e-061811677382337427be3c11ecd03e9fa2c2e831a9674c6a7
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL PFKP CLCNKA CLCNKB PRSS53 NIPAL2 ATP1A1

6.01e-0618316776b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRFN1 LAG3 ADGRB2 SIRPG TUBGCP6 CD8B PCBP4

6.01e-061831677cea27d5e0ec1145d4606c41c18de29035b4aeabe
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|368C / Donor, Lineage, Cell class and subclass (all cells)

FMO4 HLCS RPUSD4 CD8B DCLRE1C STARD9 AP5B1

7.42e-061891677610d7cc1fc923dbd67d3b71f94d529a658982f87
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SDSL LAG3 WDR81 CSF1R SIGLEC1 SDS OPLAH

7.42e-061891677b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 PFKP CLCNKA CLCNKB NIPAL2 ATP1A1 ATP4A

7.95e-0619116775a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 PFKP CLCNKA CLCNKB NIPAL2 ATP1A1 ATP4A

7.95e-06191167778bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ERMP1 CLCNKA CLCNKB ATP1A1 TNS1 SORL1

7.95e-061911677297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA4 ERMP1 CLCNKA CLCNKB ATP1A1 TNS1 SORL1

7.95e-061911677e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ABCC6 SLC52A3 HMCN1 ATP2A1 ANKRD7

9.28e-067516753167beedef7304697e9577270cdeacfc9743cee1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ABCC6 SLC52A3 HMCN1 ATP2A1 ANKRD7

9.28e-0675167570c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ABCC6 SLC52A3 HMCN1 ATP2A1 ANKRD7

9.28e-0675167526d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERMP1 IGSF11 KCNA1 KCNA6 KNDC1 PCDH9 PLXNB3

1.00e-051981677731a90f7e68b19e387499d63e3979af78b503b0c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERMP1 KCNA1 KCNA6 KNDC1 PCBP4 PCDH9 PLXNB3

1.04e-05199167767d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABCA4 LEPR PRX SLC22A6 IGFALS ATP2A1

1.21e-0513516767e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABCA4 LEPR PRX SLC22A6 IGFALS ATP2A1

1.21e-0513516764cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABCA4 LEPR PRX SLC22A6 IGFALS ATP2A1

1.21e-0513516766bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABCA4 LEPR PRX SLC22A6 IGFALS ATP2A1

1.21e-05135167697989546826bf3739e1b86a10832a457fd37c5d2
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MPL SLC4A3 SLC10A1 SLC45A3 SIGLEC6 AHNAK2

2.28e-051511676bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LAG3 C4orf50 ARHGEF10L CD8B MEGF8 IL9R

2.55e-051541676692eb053620db86d301b09bf743ab45fccc245be
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl-Cadm2_(Layer_2/3,_Cadm2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

C4orf50 EPX SPATA25 IL9R

3.14e-05481674bbfc33299ea8e6895dd4d21a7dd38bec33563127
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NWD1 ARHGEF10L TGFBR1 CSF1R PTPRJ GUSB

3.27e-0516116768937f6b92cb2a93ea8c4780d9200a518c3112e53
ToppCellBac-SEP-Myeloid-tDC|Bac-SEP / Disease, Lineage and Cell Type

SDSL SPNS3 NAGS MEGF8 DAAM1 PROC

3.75e-0516516768728f927502e56f2768b4224e9111939d3d7815a
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP2 CEP192 STIL LEPR DDX11 CCNE2

3.75e-05165167696f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP1 LAG3 RUSC1 SPNS3 CD8B ATP2A1

4.02e-051671676e0f2509e86302eca8352821bce12597f6c51fc24
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

KALRN ACR PRX STARD9 NRG3 DISP1

4.02e-0516716765af9127bae05768a5164d5708a4ad37edca99324
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP1 LAG3 RUSC1 SPNS3 CD8B ATP2A1

4.02e-051671676b25646b6653cd8814dbeae4c74ce899ede105200
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

TRIM58 LAG3 SPNS3 SIRPG KCND1 PCBP4

4.29e-051691676bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCelldroplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL BPIFB3 LAG3 SPNS3 ATP2A1 ATP4A

4.89e-0517316768fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCelldroplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL BPIFB3 LAG3 SPNS3 ATP2A1 ATP4A

4.89e-051731676f663571aaae2365660a8b526c355f4bd1a124a74
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRME1 CSF1R MEGF8 MAP4K1 PDE4DIP PCBP4

5.05e-05174167655cc8300489d11322724159ec7d0e1d32a702e91
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KALRN NWD2 NPTXR ATP1A1 VWA5B1 SORL1

5.21e-051751676ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

MPL TRIM58 CLCNKB CXCL5 TNS1 PLXNB3

5.21e-0517516765ca3369ce2c2bb88ba097260195aecd67cec1a3a
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KALRN NWD2 NPTXR ATP1A1 VWA5B1 SORL1

5.21e-05175167621f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early|lymph-node_spleen / Manually curated celltypes from each tissue

MPL TRIM58 KCND3 CXCL5 TNS1 PLXNB3

5.38e-05176167650fe3fd862dd6a6550ebb8c27f337cde468efedc
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDSL LAG3 SPNS3 EPX PLEKHG5 SLC45A3

5.55e-0517716769b4c1ca5c6fca9a7a936dad49a04155903ef9c32
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERMP1 HMCN1 CLCNKB KNDC1 ATP1A1 SORL1

5.55e-051771676c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 HMCN1 CLCNKA ATP1A1 KLHL14 PCDH9

5.73e-0517816764df6218b20c2f076c22346d23260964cc0d73e65
ToppCell368C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SP2 LRFN1 SMARCAL1 SLC10A1 LINC02908 PCDH9

5.73e-05178167650bb1f2c6a8d050ff2af217fd76c3b1b7b4a4a69
ToppCellCOVID-19_Convalescent-PLT_1|World / Disease Group and Platelet Clusters

ZNF142 TRIM58 BRME1 ZNF275 CD8B TNS1

5.91e-051791676d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCellHealthy_Control-Lymphoid-T-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SPNS3 SIRPG CD8B CD8B2 NPTXR CCNE2

5.91e-0517916764cd0bb3a99f85ff599b4b79a6a9ace3e51f8b296
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NUDT8 SRCAP SLC4A3 KCND3 DISP1 PROC

5.91e-051791676140dd7dbac48f5f07279f31bf971d7fbd41fa18b
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN ERMP1 CLCNKA CLCNKB ATP1A1 ATP4A

6.09e-051801676fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT7 KCNA1 SLC10A1 KCNA6 SIGLEC1 PLXNB3

6.09e-051801676da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

LAG3 ARHGEF10L CD8B MEGF8 STARD9 IL9R

6.09e-051801676f24d4cbba4cb50fce3b3d9c4629aa856d9b05358
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRME1 STIL PFKP CD8B MAP4K1 ANKRD7

6.09e-0518016768cef63866c205df3825df84ce51fa61aa04ae491
ToppCellmild_COVID-19_(asymptomatic)-cDC|World / disease group, cell group and cell class (v2)

SPNS3 SLC4A3 GPR157 SIGLEC1 SDS PROC

6.09e-05180167668d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT7 KCNA1 SLC10A1 KCNA6 SIGLEC1 PLXNB3

6.09e-0518016765b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT7 KCNA1 SLC10A1 KCNA6 SIGLEC1 PLXNB3

6.09e-05180167650758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN ERMP1 CLCNKA CLCNKB ATP1A1 ATP4A

6.09e-0518016766763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF11 KCNA1 KCNA6 ATP1A2 PCDH9 PLXNB3

6.48e-051821676d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCellImmune_cells-Dendritic_cells|Immune_cells / Lineage and Cell class

LAG3 SPNS3 TGFBR1 DCLRE1C ATP1A1 ATP2A1

6.48e-05182167699c7d4f1e7cd745643ba64b59190113bcd4e348e
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

GALNT14 KALRN PRX STARD9 NRG3 DISP1

6.48e-0518216768b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF11 KCNA1 KCNA6 ATP1A2 PCDH9 PLXNB3

6.48e-051821676e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BRME1 IGSF11 ADGRV1 GPR157 SCRIB SHCBP1L

6.48e-051821676e6968e0bd9cef92052d04ac54e2dd746b37623f6
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC6 IGFALS SLC45A3 SLC27A5 PROC OPLAH

6.68e-051831676d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF11 STIL KCNA1 KCNA6 ATP1A2 PLXNB3

6.88e-051841676a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCellTuft|World / Class top

ADGRB2 PNPLA6 PRSS53 ATP1A2 ATP2A3 ATP4A

7.30e-051861676f4d83f15ab7b49c0920a322cd832413ece7c9948
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 KALRN ADGRB2 SLC4A3 SLC8A2 CD8B

7.30e-0518616767278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 CLCNKA CLCNKB ATP1A1 PCDH9 SORL1

7.52e-05187167652b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCellTuft-tuft-2|World / Class top

ADGRB2 PNPLA6 PRSS53 ATP1A2 ATP2A3 ATP4A

7.52e-0518716764ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

ABCA4 BRME1 HEXD PRX DNAJB5

7.63e-051161675f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF11 PRX KCNA1 KCNA6 ATP1A2 PLXNB3

7.75e-0518816768385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF11 PRX KCNA1 KCNA6 ATP1A2 PLXNB3

7.75e-051881676cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 HMCN1 CLCNKA CLCNKB ATP1A1 PCDH9

7.75e-0518816763cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 HMCN1 CLCNKA CLCNKB ATP1A1 PCDH9

7.98e-051891676f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT14 IGFALS PRSS53 PDE4DIP ATP2A2 ATP2A3

8.45e-051911676f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PFKP CLCNKA CLCNKB NIPAL2 ATP1A1 SORL1

8.70e-051921676e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN ERMP1 CLCNKA CLCNKB ATP1A1 ATP4A

8.70e-0519216766fb56d062c35617b18b927704bf5fba894faed81
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PFKP CLCNKA CLCNKB NIPAL2 ATP1A1 SORL1

8.70e-05192167661c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERMP1 SLC4A3 CLCNKA CLCNKB ATP1A1 ATP4A

8.95e-051931676b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERMP1 SLC4A3 CLCNKA CLCNKB ATP1A1 ATP4A

8.95e-051931676241a60d1f0d5832638fb3e1e4b7afa7387ea3c75
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN ERMP1 CLCNKA CLCNKB ATP1A1 ATP4A

8.95e-051931676fa8bcf2a5ab7b08fae98a1466a936995142b4309
ToppCellmedial-2-Hematologic-Myeloid_Dendritic_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPNS3 CSF1R KCNA6 KCND1 MAP4K1 PROC

9.47e-05195167654a404ee1b97d0659fcffafb20d11f878ed453d4
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPNS3 CSF1R KCNA6 KCND1 MAP4K1 PROC

9.47e-051951676c0d1ecb378bb482a8e08d7065fcca07a65687dac
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_2-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPNS3 CSF1R KCNA6 KCND1 MAP4K1 PROC

9.47e-05195167635a5302b8b3e76bc92dc38979400c979f0e86550
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT14 RUSC1 IGFALS PRSS53 ATP2A2 ATP2A3

9.47e-05195167658b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TRIM58 IGSF11 OPCML PRX ATP1A2 PCDH9

9.74e-051961676b6226163d9fc93ecfff2115bb74408303a000490
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SDSL CSF1R PDE4DIP SIGLEC1 SDS AHNAK2

9.74e-051961676bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SDSL CSF1R PDE4DIP SIGLEC1 SDS AHNAK2

9.74e-051961676072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAG3 SPNS3 SIRPG CD8B CD8B2 MAP4K1

1.00e-041971676adc7bf2120fad4aea58123d882a8cf18ed4174d0
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGSF11 OPCML STARD9 ATP1A2 PCDH9 PLXNB3

1.00e-041971676e239caae24f40564a24ad909754f5436f767ccdb
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAG3 SPNS3 SIRPG CD8B CD8B2 MAP4K1

1.00e-041971676e133bd09efc6d7f539fc1a1ac7a945f07103d6e6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERMP1 IGSF11 KCNA1 KNDC1 PCDH9 PLXNB3

1.03e-04198167643a2ce64fa309bac89a44ea320e87ae2cc39f782
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD4+_Tem|Bac-SEP / Disease, condition lineage and cell class

FMO4 BRME1 DUOX1 SACS KCND1 KCND3

1.03e-041981676292b26f316f016b50d07689f84772eec46060251
ComputationalNeighborhood of CYP2B6

ABCC6 IGFALS SDS SLC27A5 PROC

1.00e-04491035GNF2_CYP2B6
DrugAC1L1JAO

DLAT ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ALOX15B

1.73e-07571647CID000004955
Drug1sqc

ATP2A1 ATP2A2 ATP2A3 ATP2B3

5.27e-07101644CID000444279
Drug2,5-dimethylquinone

ATP2A1 ATP2A2 ATP2A3 ATP2B3

8.23e-07111644CID000008718
Drugsuccinate

IREB2 NFS1 NAGS SLC22A6 DLAT SIGLEC1 PCBP4 ATP2A1 ATP2A2 ATP2A3 ATP2B3 SDS ALOX15B

1.14e-0633916413CID000001110
Drug1vyq

ATP2A1 ATP2A2 ATP2A3 ATP2B3

1.23e-06121644CID004369390
Drugp-hydroxyhippuric acid

ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.46e-06141644CID000151012
Drugverapamil

ABCA4 BIRC6 ABCC6 KCNA1 KCNA6 KCNA10 KCND1 KCND3 GUSB ATP1A1 ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.79e-0649016415CID000002520
DrugAC1L88YH

ATP2A1 ATP2A2 ATP2A3 ATP2B3

5.74e-06171644CID000374551
Drugacetyl phosphate

PFKP DLAT ATP2A1 ATP2A2 ATP2A3 ATP2B3 PROC

7.06e-06981647CID000000186
DrugNSC 234205

ATP1A1 ATP1A2 ATP2A1 ATP2A3

7.34e-06181644CID000010104
Drugacetazolamide

SLC22A6 KCNA1 KCNA6 DLAT ATP2A1 ATP2A2 ATP2A3

1.26e-051071647CID000001986
Drugcompound 48/80

EPX GUSB ATP1A2 ATP2A1 ATP2A2 ATP2A3 ATP2B3 ALOX15B

1.42e-051511648CID000104735
Drugagelasine B

GUSB ATP2A1 ATP2A2 ATP2A3 ATP2B3

1.97e-05461645CID006439899
DrugC04226

SDSL IREB2 SDS

2.00e-0581643CID000151255
Drug3-methylitaconate

SDSL IREB2 SDS

2.00e-0581643CID006438940
DrugAC1L25Y6

ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.07e-05231644CID000015465
Druglanthanum chloride hydrate

ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.07e-05231644CID000165791
DrugAC1L1G0K

UGT1A6 ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.69e-05491645CID000003473
Drugcyhexatin

ATP2A1 ATP2A2 ATP2A3 ATP2B3

2.92e-05251644CID005364545
Drugdodecyl ether

ATP2A1 ATP2A2 ATP2A3 ATP2B3

3.43e-05261644CID000020667
DrugATP-EDC

ATP2A1 ATP2A2 ATP2A3

4.24e-05101643CID000195647
Drugoctaethylene glycol

ATP2A1 ATP2A2 ATP2A3 ATP2B3

5.36e-05291644CID000078798
DrugAC1MMLID

SLC8A2 ATP1A1 ATP2A1 ATP2A2 ATP2A3 ATP2B3

5.45e-05921646CID000013245
Drugtoxaphene

SCRIB ATP2A1 ATP2A2 ATP2A3 ATP2B3

6.14e-05581645CID005284469
Drugoltipraz

UGT1A6 ADGRV1 ABCC6 SLC10A1 GUSB UGT2A1 OPLAH

6.21e-051371647CID000047318
Drugsanguinarine

GUSB ATP2A1 ATP2A2 ATP2A3 ATP2B3

7.23e-05601645CID000005154
DiseaseBrody myopathy (implicated_via_orthology)

ATP2A1 ATP2A2 ATP2A3

1.65e-0731633DOID:0050692 (implicated_via_orthology)
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A2 ATP4A

5.70e-0671633DOID:0060178 (implicated_via_orthology)
DiseaseBartter disease type 4B

CLCNKA CLCNKB

3.03e-0521632cv:C4310805
DiseaseBartter disease type 3 (implicated_via_orthology)

CLCNKA CLCNKB

3.03e-0521632DOID:0110144 (implicated_via_orthology)
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

3.03e-0521632613090
DiseaseBARTTER SYNDROME, TYPE 4B

CLCNKA CLCNKB

3.03e-0521632C2751312
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

3.03e-0521632C4310805
DiseaseBartter disease type 4b (is_implicated_in)

CLCNKA CLCNKB

3.03e-0521632DOID:0110146 (is_implicated_in)
DiseaseBartter disease (implicated_via_orthology)

CLCNKA CLCNKB

3.03e-0521632DOID:445 (implicated_via_orthology)
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A2 ATP4A

3.51e-05121633DOID:863 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

KALRN KCNA1 KCNA6 KCNA10 ATP1A1 ATP1A2 ATP4A

3.57e-051631637DOID:1826 (implicated_via_orthology)
Diseaseresponse to olanzapine

HIVEP1 ADGRV1 ATP1A2

7.17e-05151633GO_0097333
DiseaseOMENN SYNDROME

RAG2 DCLRE1C

9.07e-0531632603554
DiseaseReticuloendotheliosis, familial, with eosinophilia

RAG2 DCLRE1C

9.07e-0531632C2931884
DiseaseOmenn syndrome (is_implicated_in)

RAG2 DCLRE1C

9.07e-0531632DOID:0060010 (is_implicated_in)
DiseaseHistiocytic medullary reticulosis

RAG2 DCLRE1C

9.07e-0531632cv:C2700553
Diseasemaximal midexpiratory flow rate

GALNT14 IGSF11 TUBGCP6

1.76e-04201633EFO_0004313
DiseaseConn Syndrome

ATP1A1 ATP2B3

4.48e-0461632C1384514
DiseaseBartter syndrome

CLCNKA CLCNKB

4.48e-0461632cv:C0004775
DiseaseHyperaldosteronism

ATP1A1 ATP2B3

4.48e-0461632C0020428
DiseaseDelayed Puberty

LEPR IGFALS

6.25e-0471632C0034012
DiseaseHypertensive disease

LEPR CLCNKA ATP1A1 ATP1A2 ATP2B3 PROC

6.78e-041901636C0020538
DiseaseAdenoma, Microcystic

ATP1A1 ATP2A3 ATP2B3

1.03e-03361633C0205648
DiseaseAdenoma, Monomorphic

ATP1A1 ATP2A3 ATP2B3

1.03e-03361633C0205649
DiseaseAdenoma, Basal Cell

ATP1A1 ATP2A3 ATP2B3

1.03e-03361633C0205646
DiseaseFollicular adenoma

ATP1A1 ATP2A3 ATP2B3

1.03e-03361633C0205647
DiseasePapillary adenoma

ATP1A1 ATP2A3 ATP2B3

1.03e-03361633C0205650
DiseaseAdenoma, Trabecular

ATP1A1 ATP2A3 ATP2B3

1.03e-03361633C0205651
DiseaseAdenoma

ATP1A1 ATP2A3 ATP2B3

1.03e-03361633C0001430
Diseaseheart disease (implicated_via_orthology)

ATP2A1 ATP2A2 ATP2A3

1.21e-03381633DOID:114 (implicated_via_orthology)
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

CLCNKA CLCNKB

1.33e-03101632DOID:12387 (implicated_via_orthology)
Diseaselinguistic error measurement, specific language impairment

HLCS GPR157

1.33e-03101632EFO_0007798, EFO_1001510
DiseaseInherited neuropathies

KCNA1 PNPLA6 SACS

1.41e-03401633C0598589
Diseasehyperhomocysteinemia (biomarker_via_orthology)

ATP1A1 ATP1A2

1.93e-03121632DOID:9279 (biomarker_via_orthology)
DiseaseHematologic Neoplasms

MPL CSF1R

1.93e-03121632C0376545
Diseasesevere combined immunodeficiency (is_implicated_in)

RAG2 DCLRE1C

2.64e-03141632DOID:627 (is_implicated_in)
Diseaseanemia (implicated_via_orthology)

IREB2 SLC4A3

3.04e-03151632DOID:2355 (implicated_via_orthology)
DiseaseR-6-hydroxywarfarin measurement

NWD1 CLCNKB SIGLEC6 PCDH9

3.74e-031141634EFO_0803327
DiseaseFeeding difficulties

RARS1 FCSK

4.38e-03181632C0232466
Diseaseresponse to platinum based chemotherapy

SDSL ANKRD7

4.38e-03181632EFO_0004647
Diseaseglucose homeostasis measurement, acute insulin response measurement

ATP2A2 ATP2A3

4.38e-03181632EFO_0006831, EFO_0006896
DiseaseAge-related macular degeneration

ABCA4 HMCN1

4.38e-03181632cv:C0242383
DiseaseCannabis use initiation

C4orf50 GPR157

4.38e-03181632EFO_0007586
DiseaseHydrops Fetalis

GUSB ATP1A2

4.88e-03191632C0020305
Diseasesuperior temporal gyrus volume measurement

BOK ANKRD7

4.88e-03191632EFO_0010331
DiseaseOmenn Syndrome

RAG2 DCLRE1C

4.88e-03191632C2700553
DiseaseSevere Combined Immunodeficiency

RAG2 DCLRE1C

5.40e-03201632C0085110

Protein segments in the cluster

PeptideGeneStartEntry
ATLVQPVGSPLSLEC

TRBV30

26

A0A0K0K1B3
LELAGSPSVPLVIGC

ADGRB2

926

O60241
VESPPSLKLVLIGGC

ALG11

331

Q2TAA5
TVVLVGCVPFLEQPA

SLC4A3

516

P48751
PGLLCPVVDSVLGVV

BPIFB3

191

P59826
CLTVGPGPVRTLLSL

ARHGEF10L

966

Q9HCE6
CTVNIPTIDGRVIPL

DNAJB5

276

O75953
GRPILLTDVLIPTCG

BIRC6

1796

Q9NR09
TAIALIGCPPLVLLD

ABCA4

2081

P78363
EICPSSPILENALVG

ALS2

76

Q96Q42
NDIALVEITPPISCG

ACR

141

P10323
PRFGEICNISLLVTP

ADGRV1

631

Q8WXG9
VLSGGISPCIIIETP

CCNE2

61

O96020
LEPVLPCVAALSSVG

ACAP3

556

Q96P50
ITCASPPEVVGLDLR

IGFALS

581

P35858
LPGVDVLLEVFPTCS

CUEDC2

146

Q9H467
AAPVPGRLAEVCAVL

BOK

56

Q9UMX3
GLSLVPAPGLVLTCL

C3orf36

21

Q3SXR2
STARPGCIIALDPIT

DMXL1

806

Q9Y485
VVCALVGVLVPELPD

DISP1

201

Q96F81
EIPPDVVLASILAGC

ERMP1

616

Q7Z2K6
AIPEGLPAVITTCLA

ATP2A1

306

O14983
AIPEGLPAVITTCLA

ATP2A3

306

Q93084
LTCIAVVGIEDPVRP

ATP2B3

671

Q16720
IVLVLDITSGDPCPV

NWD1

1321

Q149M9
LIPDCPDIIVFITSA

NWD2

1486

Q9ULI1
LADVLSAPCPFIVGI

DENND4A

456

Q7Z401
IRVDLPLGSPAVNCT

RAG2

236

P55895
LGLPVSLTLPEVVGC

IREB2

306

P48200
SAAVLVPLCSVRGVP

NUDT8

31

Q8WV74
VLSDLVSVETPGCPA

DUOX1

106

Q9NRD9
SSVPIIPSVGLEETC

NRG3

596

P56975
GCISLLNITEPVLGP

NOL9

346

Q5SY16
PVTLRLVIPASQCGS

PCBP4

101

P57723
ICAVILESPPKGATI

PCBP4

166

P57723
PVVEISLISRLPFCG

OR6N1

156

Q8NGY5
NLATVAILPVCAEVP

PNPLA6

781

Q8IY17
NITVCPVLGDIEGTP

PTPRJ

431

Q12913
ICSLSGVLVIALPVP

KCND1

391

Q9NSA2
ICSLSGVLVIALPVP

KCND3

386

Q9UK17
LCAIAGVLTIALPVP

KCNA1

391

Q09470
VPTPLVVGLGAACEV

NFS1

296

Q9Y697
LSLCVALPPGLAVSV

MMS19

116

Q96T76
VTLECLASGVPPPDV

HMCN2

1911

Q8NDA2
AGEATAPVEVCVVPL

LRFN1

376

Q9P244
ANIPLPLGTVTILCI

ATP1A1

796

P05023
PVGCALSTLLISIPL

HLCS

516

P50747
GAVELLCPAPSIDAV

PLXNB3

826

Q9ULL4
TRDVPLGTPLCIIVE

DLAT

281

P10515
LVPLSAIPGSVVAEV

PCDH9

686

Q9HC56
LATLVLAQPCEGTDP

EPX

11

P11678
IALLEATPDTPACVV

PFKP

331

Q01813
LIVPPACAVGSEGVI

FKBP15

256

Q5T1M5
DIAACIGTKPSIPLL

FMO4

436

P31512
PEFLVPLVDVTCLLG

KALRN

2471

O60229
VLCELLPAGVPSLAA

HEXD

306

Q8WVB3
AGGSLLVLVPTLCPL

MEGF8

886

Q7Z7M0
TLCALALDVTSVGPP

MRS2

21

Q9HD23
VTCGPLLLEPETISE

LEPR

906

P48357
QSTVLDCGPRLPVEV

TUBGCP6

1311

Q96RT7
PGSLGKLLCEVTPVS

LAG3

361

P18627
ESGSIPILCPIGETA

NAGS

251

Q8N159
LVACCLAGQPTVLTP

AP5B1

471

Q2VPB7
VPCLIDTDTLITPFV

NUDT7

111

P0C024
SCIVPLEFVTEGPLE

PCDHGC4

101

Q9Y5F7
ALPLSCPLETVFVVG

DDX11

916

Q96FC9
GVSSCPELQIPLFLV

OR8J3

16

Q8NGG0
LGAVICIIASVPLAA

NPTXR

16

O95502
NPVVPIGCLATAAAL

HIGD2A

46

Q9BW72
VLECIAEGVPTPRIT

HMCN1

3731

Q96RW7
AILPCVADGIPTPAI

HMCN1

4186

Q96RW7
CLSVITLFPGAPVVL

GALNT14

476

Q96FL9
SSVTLLCLAIGRPEP

OPCML

151

Q14982
CSTILNVAFPPEVIG

SLC10A1

266

Q14973
LSQTIVPICLPDSGL

PROC

311

P04070
CAIAGVLTIALPVPV

KCNA10

441

Q16322
GVSSCPELQIPLFLV

OR8J1

16

Q8NGP2
SVVSCLLEGPVQLGP

FCSK

366

Q8N0W3
VAVLEILGAVCLVPG

DAAM1

221

Q9Y4D1
AIPEGLPAVITTCLA

ATP2A2

306

P16615
PLPLGTVTILCIDLG

ATP1A2

796

P50993
TLDPGTCLAAVTVEP

C4orf50

201

Q6ZRC1
TCLAAVTVEPGLPAQ

C4orf50

206

Q6ZRC1
PLCSPVTLGLLVAGV

CD8B2

166

A6NJW9
PCLLTDPVLEAGVSL

CSF1R

126

P07333
NLLCLAVGRPEPTVT

IGLON5

151

A6NGN9
VILLCSSEEGIPRPT

IGSF11

161

Q5DX21
VCSPEGSISILPTIL

HEATR5A

1736

Q86XA9
ILGVSIQFLCSPRPE

HEATR5B

1591

Q9P2D3
SLPPEVLSIEGAAIC

KLHL11

591

Q9NVR0
LCAIAGVLTIALPVP

KCNA6

441

P17658
VAEPLAGPACVTVIL

KLHL14

606

Q9P2G3
SPGCQLLVETLGVPL

BRME1

141

Q0VDD7
IVVTLLPAGHCPGSV

DCLRE1C

106

Q96SD1
LDSVIGTELCPSPIP

C5orf60

21

A6NFR6
PLCSPITLGLLVAGV

CD8B

166

P10966
EPAILPVCAARLAGS

LINC02908

81

Q6ZV77
IVVIDECPGVGLALP

GUSB

401

P08236
VLTLCGSPAVQTPVL

GPR157

246

Q5UAW9
QRTALILAVSGEPPC

ANKRD7

191

Q92527
TGIPCLTPSELEAFL

EPHX3

251

Q9H6B9
EIAERSPCVAGVIPV

GPR142

146

Q7Z601
ELSPLVCSPAGVSRL

CEP192

1026

Q8TEP8
GLEPCTLPVIVNIAA

KNDC1

1201

Q76NI1
PGSESLLLTVPAAVI

CUL9

841

Q8IWT3
GCLSEPVASALIPVK

CRYBG1

386

Q9Y4K1
LVAVCPIPAAGLDVT

HDAC6

1116

Q9UBN7
LRTPLPSLVVIVCGG

SDS

291

P20132
GAVPVAASAVTVLLP

SLC22A6

491

Q4U2R8
PLIPRTILEEGQTCV

SACS

801

Q9NZJ4
TVSVPLPLGCITILF

ATP4A

806

P20648
VPGPSSSLCALLVLL

CXCL5

11

P42830
GSTEPCVLPFQVLLE

PCDHB6

96

Q9Y5E3
IATLPPVNATCDVIL

ALOX15B

591

O15296
ALLTGPGSELPAVCI

MAP4K1

661

Q92918
PDVGHLVLTTLCPAL

RUSC1

521

Q9BVN2
PGVQLCITDVLPILA

RPUSD4

121

Q96CM3
VPGCSIPLTIVKSDG

RARS1

366

P54136
GAAICLPSVKPVVSS

TAF4B

476

Q92750
SVPVCSLPTCLGQVL

SZT2

1581

Q5T011
VLGSVGVPTPLVSCD

RGL2

536

O15211
IDVSEGPLIPRTSIC

MRPL39

261

Q9NYK5
FTLVALLPPGALCEV

SORL1

16

Q92673
PSCLSEVPIIFTLLG

SLC52A3

66

Q9NQ40
LTVPQGCLLAVVGPV

ABCC6

651

O95255
APITLIAPLGCVSVT

NIPAL2

111

Q9H841
PCLIIDSNSTILVEP

OPLAH

691

O14841
LPSLSPDCINVVVTG

SMARCAL1

501

Q9NZC9
PALCVTLAGLIPFVA

TMEM69

96

Q5SWH9
VLPLPGAQDTVTCIR

POLR1H

26

Q9P1U0
PESLTVQEGLCVLVP

SIGLEC6

36

O43699
SIPFVGILVEVTCEP

SHCBP1L

176

Q9BZQ2
ALPPEIGGCVALSVL

SCRIB

326

Q14160
TPASVGLTPRICEGL

STARD9

116

Q9P2P6
ILRGSECTVVLPPEA

IL9R

96

Q01113
TTLTVLPEGEELPLC

SRCAP

2631

Q6ZRS2
LHCTVTSLLPVGPVL

SIRPG

51

Q9P1W8
LSLGLCSPVEPVVVA

SPATA25

26

Q9BR10
LQAEGCLPPSLTSVV

SDSL

291

Q96GA7
CLPPSLTSVVVIVCG

SDSL

296

Q96GA7
PVLGLVCVPLLGSAS

SLC45A3

61

Q96JT2
LGPVELAAVIAGPVC

TGFBR1

121

P36897
LCIPLPSADLVVQAG

AHNAK2

1871

Q8IVF2
ILARGCPTEPVTLTL

CLCNKA

621

P51800
ILAAGCPTEPVTLKL

CLCNKB

621

P51801
LQTVPVTLLGPRACS

PRSS53

431

Q2L4Q9
SLSELCLAVPAPGIR

PLEKHG5

901

O94827
LVAVVGCLLVPPAEA

TMEM9

6

Q9P0T7
VPECLEITPTASLPG

STIL

106

Q15468
PELLEGTCTPVQLVA

MINPP1

71

Q9UNW1
VIPGAEPLICASSLL

SPNS3

336

Q6ZMD2
PASLCAGEPTALLVL

SLC27A5

166

Q9Y2P5
ALLAATCSKIGPPAV

SP2

36

Q02086
LPTLPCLETREGAVS

PRX

306

Q9BXM0
PVQCVSPELALTIAL

TNS1

921

Q9HBL0
GQLALVLCTVDSRPP

SIGLEC1

1186

Q9BZZ2
GPTVIQLIATETCCP

MPL

181

P40238
LVTGPCLLAGLESPS

VWA5B2

221

Q8N398
PIPTEPGCLLVEATA

ZNF142

51

P52746
PQVPDVSCLVLATGL

WSB2

116

Q9NYS7
ALFTDPALPCGVILA

UGT1A6

146

P19224
SVELACGSGPAPLLV

VSIG10L2

51

P0DP72
CVSLLGVPVLNPALV

ZNF275

6

Q9NSD4
VLVSDPVFPCGDIVA

UGT2A1

146

P0DTE4
PILVRQVCTTEPLDG

HIVEP1

1796

P15822
GVAELSSVVPCIPIG

HIVEP1

2456

P15822
VLGDIVSGPVLSCLL

WDR81

1286

Q562E7
CDATPLILPPTTIAG

TRIM58

451

Q8NG06
PVPEGLCVIVSCNLS

SIGLEC16

31

A6NMB1
SGAVRVLLPAVCAPT

VWA5B1

156

Q5TIE3
LPPTVDVVALGRCSL

KIAA1522

301

Q9P206
LVGVTLLLAAPPCSG

SLC8A2

6

Q9UPR5
NTCAPLATLVLAPEI

NACA

716

E9PAV3
PLLLGCCETPVVSLA

PDE4DIP

1726

Q5VU43