Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainBROMODOMAIN_1

TRIM33 PBRM1 ATAD2B

2.27e-0537283PS00633
DomainBromodomain

TRIM33 PBRM1 ATAD2B

2.46e-0538283PF00439
DomainBROMODOMAIN_2

TRIM33 PBRM1 ATAD2B

3.10e-0541283PS50014
DomainBROMO

TRIM33 PBRM1 ATAD2B

3.33e-0542283SM00297
DomainBromodomain

TRIM33 PBRM1 ATAD2B

3.33e-0542283IPR001487
Domain-

TRIM33 PBRM1 ATAD2B

3.33e-05422831.20.920.10
DomainBromodomain_CS

PBRM1 ATAD2B

6.89e-0426282IPR018359
DomainHAD-like_dom

PITPNM2 ATP2C2

6.22e-0379282IPR023214
DomainIQ

MYO18B SCN5A

6.53e-0381282SM00015
DomainIQ_motif_EF-hand-BS

MYO18B SCN5A

8.00e-0390282IPR000048
DomainIQ

MYO18B SCN5A

8.52e-0393282PS50096
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

TRIM33 PBRM1 ATAD2B

3.04e-057528325593309
Pubmed

A high-density association screen of 155 ion transport genes for involvement with common migraine.

ATP2C2 SCN5A

4.10e-051228218676988
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PITPNM2 LARP1 TRIM33 PPP2R2D MDC1

5.88e-0552928514621295
Pubmed

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.

AKAP13 DEPTOR

6.52e-051528223583980
Pubmed

Report of the sixth international workshop on human chromosome 3 mapping 1995.

NKTR SCN5A

1.30e-04212828641130
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

LARP1 FRY PBRM1 HSPA7 ZNF804B

1.43e-0463928523443559
Pubmed

Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.

PBRM1 MDC1

2.68e-043028231043422
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

LARP1 TRIM33 PBRM1 PPP2R2D

2.78e-0439828435016035
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

LARP1 NKTR PBRM1 MDC1

4.07e-0444028434244565
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PITPNM2 FRY PBRM1 PPP2R2D

5.42e-0447528431040226
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

FRY MDC1 ZNF804B

5.44e-0419928323382691
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

LARP1 NKTR ZNF804B SCN5A

5.51e-0447728431300519
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

LARP1 MDC1

5.53e-044328234672947
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

LARP1 AKAP13 PKN2 PBRM1

6.72e-0450328416964243
Cytoband3p21

PBRM1 SCN5A

1.87e-04332823p21
CytobandEnsembl 112 genes in cytogenetic band chr3p22

NKTR SCN5A

5.64e-03184282chr3p22
Cytoband6p21.3

MDC1 NFKBIL1

1.02e-022502826p21.3
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

AKAP13 FRY MYO18B SCN5A

6.46e-0619528475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AKAP13 PKN2 NKTR ATAD2B

7.14e-0620028412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TRIM33 AKAP13 NKTR

8.19e-05135283b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DEPTOR SLC45A4 GABRR3

8.19e-051352838521107817df49efd9a2e81078c8535ed33e729c
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY MYO18B SCN5A

1.62e-041702833f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

AKAP13 NFKBIL1 ZNF185

1.65e-041712830d14bc9688c427ba2265984987dc3eea195b19eb
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY MYO18B SCN5A

1.79e-041762839df7a124ebafb0087da0cda133a394275d7bed81
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NKTR ATP2C2 SLC45A4

1.89e-041792836e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Dendritic_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATPSCKMT MDC1 C1orf174

1.92e-04180283710526abedc8e0f9ba19ad69220df4c9468ada8f
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY MYO18B SCN5A

1.95e-04181283719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTAFR DEPTOR SLC45A4

1.95e-0418128322363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AKAP13 PTAFR ATP2C2

1.98e-0418228372e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AKAP13 PTAFR ATP2C2

1.98e-0418228305c167158815bf25d509df59ab386e1990712765
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

AKAP13 FRY MYO18B

2.04e-04184283ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY MYO18B SCN5A

2.08e-04185283549eeb521c3985bff396ea0f202db21822efa51f
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TRIM33 AKAP13 NKTR

2.14e-041872830099def970fbc828756fbf853eca2ce77b8cd342
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRY ZNF804B ATP2C2

2.21e-041892837659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

FRY MYO18B SCN5A

2.21e-041892839c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 FRY SLC45A4

2.25e-04190283f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY MYO18B SCN5A

2.25e-04190283918ad5037881212008f9f69d5df5da91fd01422c
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

AKAP13 MYO18B SCN5A

2.25e-04190283fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

FRY MYRFL DEPTOR

2.32e-04192283e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TRIM33 NKTR ATAD2B

2.35e-041932839337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

FRY MYO18B SCN5A

2.35e-04193283dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

FRY MYO18B SCN5A

2.39e-04194283c3535f7cc0076653c72db582047cff053c322397
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRY ZNF804B ATP2C2

2.39e-04194283f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 PTAFR DEPTOR

2.42e-04195283938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell(7)_DC_2|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PTAFR DEPTOR NFKBIL1

2.42e-0419528363abdf512368a32e586f8dc87090796f19a146c6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 PTAFR DEPTOR

2.42e-04195283d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FRY PTAFR DEPTOR

2.46e-04196283ef481eb306350311207f7a29fdfa1ae3feaba4d7
ToppCellwk_08-11-Hematologic-Myeloid-Myelocyte-like|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FRY PTAFR ATP2C2

2.46e-041962834b88c96b737a747422674ad99c073b28e6febc7c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP13 PTAFR HSPA7

2.57e-04199283379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellSigmoid-ILC-ILC|Sigmoid / Region, Cell class and subclass

PITPNM2 FRY MYRFL

2.61e-042002834ac1e6d7f358003e2448eb69e545772cd261c55f
ToppCellSigmoid-(3)_ILC|Sigmoid / shred on region, Cell_type, and subtype

PITPNM2 FRY MYRFL

2.61e-04200283a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCellSigmoid-(3)_ILC-(30)_ILC|Sigmoid / shred on region, Cell_type, and subtype

PITPNM2 FRY MYRFL

2.61e-04200283c39de94623383da7b2b260eb016ddaa5da7f4350
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP13 HSPA7 ZNF185

2.61e-0420028388d713dfc792e7609bf7ecfb28f87cb748088570
ToppCellSigmoid-ILC|Sigmoid / Region, Cell class and subclass

PITPNM2 FRY MYRFL

2.61e-04200283dfb06821f1019833f5d81f9c93808219b5fef407
Diseasereticulocyte measurement

PITPNM2 LARP1 AKAP13 PKN2 DEPTOR ATAD2B SLC45A4 NFKBIL1

2.26e-061053268EFO_0010700
DiseaseCannabis use, age at onset

LARP1 ATP2C2

1.26e-0419262EFO_0004847, EFO_0007585
DiseaseBrugada syndrome

MYO18B SCN5A

1.26e-0419262MONDO_0015263
Diseasebirth weight

AKAP13 PJA1 ATAD2B SLC45A4

3.89e-04399264EFO_0004344
Diseaseobsolete_red blood cell distribution width

LARP1 TRIM33 AKAP13 PKN2 PBRM1 ATAD2B

9.37e-041347266EFO_0005192
Diseaseneutrophil count

TRIM33 AKAP13 PKN2 PPP2R2D HSPA7 SLC45A4

1.07e-031382266EFO_0004833
Diseaseidiopathic pulmonary fibrosis

AKAP13 DEPTOR

1.16e-0357262EFO_0000768
Diseaseplatelet crit

PKN2 PJA1 DEPTOR SPSB3 SLC45A4

1.29e-03952265EFO_0007985
Diseaseinterstitial lung disease

AKAP13 DEPTOR

1.59e-0367262EFO_0004244
Diseaseanorexia nervosa

TRIM33 ZNF804B

1.74e-0370262MONDO_0005351
Diseasereticulocyte count

PITPNM2 LARP1 ATAD2B SLC45A4 NFKBIL1

1.95e-031045265EFO_0007986
Diseasemean corpuscular hemoglobin concentration

LARP1 TRIM33 AKAP13 PKN2 ATAD2B

2.49e-031105265EFO_0004528
DiseaseHbA1c measurement

LARP1 ATAD2B NFKBIL1 ZNF185

2.72e-03675264EFO_0004541
Diseaseeosinophil percentage of leukocytes

PITPNM2 AKAP13 SLC45A4 NFKBIL1

3.89e-03746264EFO_0007991
DiseaseQRS-T angle

MYO18B SCN5A

3.93e-03106262EFO_0020097
Diseaseplatelet component distribution width

TRIM33 AKAP13 PKN2 ATAD2B

4.06e-03755264EFO_0007984
Diseaseatrial fibrillation

PKN2 MYO18B SCN5A

4.14e-03371263EFO_0000275
DiseasePapillary Renal Cell Carcinoma

AKAP13 PBRM1

5.67e-03128262C1306837
DiseaseRenal Cell Carcinoma

AKAP13 PBRM1

5.67e-03128262C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

AKAP13 PBRM1

5.67e-03128262C1266043
DiseaseChromophobe Renal Cell Carcinoma

AKAP13 PBRM1

5.67e-03128262C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

AKAP13 PBRM1

5.67e-03128262C1266044
Diseasecortical surface area measurement

PITPNM2 PKN2 ATAD2B MDC1 SLC45A4

5.77e-031345265EFO_0010736

Protein segments in the cluster

PeptideGeneStartEntry
ANCSVLRSSMRSLSP

AKAP13

1546

Q12802
SSSKGTIRLCDMRSS

PPP2R2D

251

Q66LE6
DRASTPRTTTMTFTC

ATP2C2

831

O75185
RKRCPSQSSSRPAAM

LARP1

1051

Q6PKG0
MGSKRRRATSPSSSV

PBRM1

1

Q86U86
TSRTTRSRTNMSSVK

MDC1

1306

Q14676
SRTRSSKTRAASCPA

ATAD2B

41

Q9ULI0
CHCRPMTSRSRSSEV

MYRFL

181

Q96LU7
SVCRPKSSMASTSRR

NFKBIL1

16

Q9UBC1
LRTEPCSRHSSSSTM

PITPNM2

691

Q9BZ72
RTACERAKRTPSSST

HSPA7

266

P48741
FMRRKSICSPSTDSS

GABRR3

406

A8MPY1
KIVSAVRRSSMSSCG

DEPTOR

271

Q8TB45
KPRAMAVTRSTSSTS

FRY

2356

Q5TBA9
ASSSCPSMSRREFRK

C1orf174

211

Q8IYL3
RRSACMLSSPESSLT

TRIM33

801

Q9UPN9
STRRMKSSCDRERSS

NKTR

471

P30414
MRSSRKCSRATTDTV

PTAFR

311

P25105
SRTSMKPRSSRGSIF

SCN5A

516

Q14524
VCSTAARSSMKVTRS

SPSB3

256

Q6PJ21
ARSSMKVTRSCASAT

SPSB3

261

Q6PJ21
PSETRSSFMSRTSKS

PKN2

361

Q16513
ASTFRGREKRPCTSM

ATPSCKMT

211

Q6P4H8
VDTKPSATSSSMRRR

SLC45A4

401

Q5BKX6
PSSMSSLRSTCSSHR

ZNF804B

716

A4D1E1
MASKCSSERKSRTSL

TIGD1

1

Q96MW7
CTLSLATDTMRTPSR

MYO18B

2131

Q8IUG5
MHRSAPSQTTKRSRS

PJA1

56

Q8NG27
SCTSRVRSPSSCMVT

ZNF185

531

O15231