Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO1D MYO9A MYO9B MYO15A

2.76e-0538924GO:0000146
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A1 COL4A3 COL4A5 COL5A3

5.94e-0546924GO:0030020
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A4 GJA1 SLC6A11 CACNA1S CACNA2D1 SFXN5 SLC11A1 TRPC1 SCNN1A ABCC9 ATP13A5 PKDREJ CHRND

6.82e-057939213GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SLC6A4 CACNA1S CACNA2D1 TRPC1 SCNN1A ABCC9 PKDREJ CHRND

1.86e-04343928GO:0005261
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAI1 MYO1D MYO9A MYO9B MYO15A

2.16e-04118925GO:0003774
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A4 SLC6A11 CACNA1S CACNA2D1 SLC11A1 TRPC1 SCNN1A ABCC9 ATP13A5 PKDREJ CHRND

2.36e-046649211GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A4 SLC6A11 CACNA1S CACNA2D1 SLC11A1 TRPC1 SCNN1A ABCC9 PKDREJ

2.93e-04465929GO:0046873
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

3.11e-046922GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

5.77e-048922GO:0032453
GeneOntologyMolecularFunctionchannel activity

SLC6A4 GJA1 CACNA1S CACNA2D1 TRPC1 SCNN1A ABCC9 PKDREJ CHRND

7.04e-04525929GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC6A4 GJA1 CACNA1S CACNA2D1 TRPC1 SCNN1A ABCC9 PKDREJ CHRND

7.13e-04526929GO:0022803
GeneOntologyMolecularFunctionendopeptidase activity

MBTPS2 ADAMTS3 ADAM20 TPP1 ADAMTS18 USP48 KLKB1 TMPRSS11B

8.32e-04430928GO:0004175
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A4 GJA1 SLC6A11 CACNA1S CACNA2D1 SFXN5 SLC11A1 SLCO2B1 TRPC1 SCNN1A ABCC9 ATP13A5 PKDREJ CHRND

9.78e-0411809214GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC6A4 CACNA1S CACNA2D1 TRPC1 SCNN1A ABCC9 PKDREJ CHRND

1.26e-03459928GO:0005216
GeneOntologyMolecularFunctionintegrin binding

SLC6A4 COL4A3 ADAM20 L1CAM SVEP1

1.30e-03175925GO:0005178
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A1 COL4A3 COL4A5 EFEMP1 COL5A3

1.78e-03188925GO:0005201
GeneOntologyMolecularFunctiontransporter activity

SLC6A4 GJA1 SLC6A11 CACNA1S CACNA2D1 SFXN5 SLC11A1 SLCO2B1 TRPC1 SCNN1A ABCC9 ATP13A5 PKDREJ CHRND

2.25e-0312899214GO:0005215
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MBTPS2 ADAMTS3 ADAM20 ADAMTS18

2.31e-03120924GO:0004222
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A4 SLC6A11 CACNA1S CACNA2D1 SLC11A1 TRPC1 SCNN1A ABCC9 PKDREJ

2.40e-03627929GO:0022890
GeneOntologyBiologicalProcesscollagen-activated tyrosine kinase receptor signaling pathway

COL4A1 COL4A3 COL4A5

1.90e-0512933GO:0038063
GeneOntologyCellularComponentextracellular matrix

COL4A1 COL4A3 COL4A5 ORM2 EFEMP1 ADAMTS3 L1CAM NAV2 ADAMTS18 NCAM1 COL5A3 MUC5B ADAMTSL3 USH2A SVEP1

2.25e-076569415GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A1 COL4A3 COL4A5 ORM2 EFEMP1 ADAMTS3 L1CAM NAV2 ADAMTS18 NCAM1 COL5A3 MUC5B ADAMTSL3 USH2A SVEP1

2.34e-076589415GO:0030312
GeneOntologyCellularComponentcollagen type IV trimer

COL4A1 COL4A3 COL4A5

1.74e-066943GO:0005587
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A1 COL4A3 COL4A5 COL5A3

2.16e-0621944GO:0098644
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A1 COL4A3 COL4A5

4.85e-068943GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A1 COL4A3 COL4A5

4.85e-068943GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A1 COL4A3 COL4A5

4.85e-068943GO:0098645
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL4A1 COL4A3 COL4A5 ORM2 EFEMP1 ADAMTS3 L1CAM NAV2 NCAM1 COL5A3 USH2A

2.59e-055309411GO:0062023
GeneOntologyCellularComponentmyosin complex

MYO1D MYO9A MYO9B MYO15A

1.44e-0459944GO:0016459
GeneOntologyCellularComponentbasement membrane

COL4A1 COL4A3 COL4A5 EFEMP1 USH2A

2.26e-04122945GO:0005604
GeneOntologyCellularComponentcollagen trimer

COL4A1 COL4A3 COL4A5 COL5A3

6.70e-0488944GO:0005581
GeneOntologyCellularComponentL-type voltage-gated calcium channel complex

CACNA1S CACNA2D1

1.28e-0312942GO:1990454
GeneOntologyCellularComponentpostsynapse

SLC6A4 SLC6A11 CACNA1S CACNA2D1 NRCAM FCGR2A MYO9A MYO9B WASF3 NCAM1 USP48 CHRND

2.01e-0310189412GO:0098794
GeneOntologyCellularComponentpostsynaptic membrane

SLC6A4 SLC6A11 CACNA2D1 NRCAM NCAM1 USP48 CHRND

2.35e-03405947GO:0045211
GeneOntologyCellularComponentsupramolecular polymer

COL4A1 COL4A3 COL4A5 GJA1 DNAI1 CACNA1S MYO9A MYO9B TRPC1 NAV3 ABCC9 COL5A3 TTLL8

2.48e-0311879413GO:0099081
DomainC4

COL4A1 COL4A3 COL4A5

2.29e-066923SM00111
Domain-

COL4A1 COL4A3 COL4A5

2.29e-0669232.170.240.10
DomainCollagen_VI_NC

COL4A1 COL4A3 COL4A5

2.29e-066923IPR001442
DomainC4

COL4A1 COL4A3 COL4A5

2.29e-066923PF01413
DomainNC1_IV

COL4A1 COL4A3 COL4A5

2.29e-066923PS51403
DomainIQ

MYO1D MYO9A MYO9B CAMTA1 MYO15A

2.62e-0571925PF00612
DomainMyosin_head_motor_dom

MYO1D MYO9A MYO9B MYO15A

3.58e-0538924IPR001609
DomainMYOSIN_MOTOR

MYO1D MYO9A MYO9B MYO15A

3.58e-0538924PS51456
DomainMyosin_head

MYO1D MYO9A MYO9B MYO15A

3.58e-0538924PF00063
DomainMYSc

MYO1D MYO9A MYO9B MYO15A

3.58e-0538924SM00242
DomainIQ

MYO1D MYO9A MYO9B CAMTA1 MYO15A

4.96e-0581925SM00015
DomainIQ_motif_EF-hand-BS

MYO1D MYO9A MYO9B CAMTA1 MYO15A

8.21e-0590925IPR000048
DomainIQ

MYO1D MYO9A MYO9B CAMTA1 MYO15A

9.60e-0593925PS50096
DomainPLAC

ADAMTS3 ADAMTS18 ADAMTSL3

1.06e-0419923PS50900
DomainPLAC

ADAMTS3 ADAMTS18 ADAMTSL3

1.06e-0419923IPR010909
DomainNeurofascin/L1/NrCAM_C

NRCAM L1CAM

1.43e-044922IPR026966
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

1.43e-044922IPR013637
DomainPLU-1

KDM5C KDM5D

1.43e-044922PF08429
DomainBravo_FIGEY

NRCAM L1CAM

1.43e-044922PF13882
DomainPeptidase_M12B_ADAM-TS

ADAMTS3 ADAMTS18 ADAMTSL3

2.17e-0424923IPR013273
Domainzf-C5HC2

KDM5C KDM5D

2.38e-045922PF02928
DomainZnf_C5HC2

KDM5C KDM5D

2.38e-045922IPR004198
DomainTIG

PLXNA3 REL CAMTA1

4.70e-0431923PF01833
DomainIPT

PLXNA3 REL CAMTA1

5.17e-0432923IPR002909
DomainCollagen

COL4A1 COL4A3 COL4A5 COL5A3

8.23e-0485924IPR008160
DomainCollagen

COL4A1 COL4A3 COL4A5 COL5A3

8.23e-0485924PF01391
DomainPeptidase_M12B_N

ADAMTS3 ADAM20 ADAMTS18

9.30e-0439923IPR002870
DomainPep_M12B_propep

ADAMTS3 ADAM20 ADAMTS18

9.30e-0439923PF01562
DomainDISINTEGRIN_1

ADAMTS3 ADAM20 ADAMTS18

1.00e-0340923PS00427
DomainReprolysin

ADAMTS3 ADAM20 ADAMTS18

1.00e-0340923PF01421
DomainADAM_MEPRO

ADAMTS3 ADAM20 ADAMTS18

1.00e-0340923PS50215
DomainDISINTEGRIN_2

ADAMTS3 ADAM20 ADAMTS18

1.00e-0340923PS50214
DomainPeptidase_M12B

ADAMTS3 ADAM20 ADAMTS18

1.00e-0340923IPR001590
DomainJmjN

KDM5C KDM5D

1.05e-0310922SM00545
DomainJMJN

KDM5C KDM5D

1.05e-0310922PS51183
DomainJmjN

KDM5C KDM5D

1.05e-0310922PF02375
DomainJmjN

KDM5C KDM5D

1.05e-0310922IPR003349
DomainDisintegrin_dom

ADAMTS3 ADAM20 ADAMTS18

1.08e-0341923IPR001762
Domainfn3

NRCAM L1CAM NCAM1 USH2A IL6ST

1.24e-03162925PF00041
DomainZINC_PROTEASE

MBTPS2 ADAMTS3 ADAM20 ADAMTS18

1.40e-0398924PS00142
Domain-

PLXNA3 NRCAM FCGR2A L1CAM NCAM1 REL CAMTA1 ADAMTSL3 USH2A IL6ST

1.56e-0366392102.60.40.10
DomainCTDL_fold

COL4A1 COL4A3 COL4A5 MRC1

1.93e-03107924IPR016187
DomainPLAC

ADAMTS18 ADAMTSL3

2.10e-0314922PF08686
DomainFN3

NRCAM L1CAM NCAM1 USH2A IL6ST

2.22e-03185925SM00060
Domain-

KDM5C KDM5D

2.42e-03159221.10.150.60
DomainBRIGHT

KDM5C KDM5D

2.42e-0315922SM00501
DomainARID_dom

KDM5C KDM5D

2.42e-0315922IPR001606
DomainARID

KDM5C KDM5D

2.42e-0315922PS51011
DomainARID

KDM5C KDM5D

2.42e-0315922PF01388
DomainIg-like_fold

PLXNA3 NRCAM FCGR2A L1CAM NCAM1 REL CAMTA1 ADAMTSL3 USH2A IL6ST

2.47e-037069210IPR013783
DomainFN3

NRCAM L1CAM NCAM1 USH2A IL6ST

3.04e-03199925PS50853
DomainNA_NEUROTRAN_SYMP_2

SLC6A4 SLC6A11

3.49e-0318922PS00754
DomainTSP_1

ADAMTS3 ADAMTS18 ADAMTSL3

3.71e-0363923PF00090
DomainFN3_dom

NRCAM L1CAM NCAM1 USH2A IL6ST

3.74e-03209925IPR003961
DomainSNF

SLC6A4 SLC6A11

3.89e-0319922PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A4 SLC6A11

3.89e-0319922PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A4 SLC6A11

3.89e-0319922PS50267
DomainNa/ntran_symport

SLC6A4 SLC6A11

3.89e-0319922IPR000175
DomainTSP1

ADAMTS3 ADAMTS18 ADAMTSL3

4.05e-0365923SM00209
DomainTSP1_rpt

ADAMTS3 ADAMTS18 ADAMTSL3

4.05e-0365923IPR000884
DomainTSP1

ADAMTS3 ADAMTS18 ADAMTSL3

4.05e-0365923PS50092
Domain-

HNRNPUL2 CCAR1

4.74e-03219221.10.720.30
Domain-

XPO6 PUM2 FRYL ARMCX2 BRAT1

4.83e-032229251.25.10.10
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A3 COL4A5 CACNA1S NCAM1 COL5A3

5.49e-0842706M7169
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A3 COL4A5 CACNA1S NCAM1 COL5A3

6.55e-0763706M11187
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A3

2.54e-0620704MM15061
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A3 COL4A5 KLKB1

4.60e-0623704M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A3 COL4A5 KLKB1

4.60e-0623704MM1427
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A3 COL4A5 ADAMTS3 COL5A3

1.25e-0561705MM14637
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A3 COL4A5

1.37e-0510703M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A3 COL4A5

1.37e-0510703MM1560
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A1 COL4A3 COL4A5 EFEMP1 ADAMTS3 ADAMTS18 NCAM1 COL5A3 KLKB1

1.65e-05300709M610
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A3

1.80e-0532704MM14924
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A3 COL4A5

1.88e-0511703M15422
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A3 COL4A5 ADAMTS3 COL5A3

1.99e-0567705M26999
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

COL4A1 CUL2 COL4A3 PLXNA3 COL4A5 CACNA1S NRCAM MYO9B TRPC1 L1CAM NCAM1 COL5A3

2.31e-055757012M29853
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A3 COL4A5

2.50e-0512703MM1526
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A3 COL4A5

3.24e-0513703MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A3 COL4A5

3.24e-0513703M12950
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A3 COL4A5 COL5A3

3.62e-0538704MM14969
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A1 COL4A3 COL4A5 NCAM1 COL5A3

3.67e-0576705M27219
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A3 COL4A5 ADAMTS3 COL5A3

3.67e-0576705MM14573
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A3 COL4A5

4.10e-0514703MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A3 COL4A5

4.10e-0514703M6487
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A3 COL4A5 COL5A3

4.91e-0541704MM15538
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A3 COL4A5

5.11e-0515703MM14922
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A1 COL4A3 COL4A5

5.11e-0515703M27161
PathwayPID_INTEGRIN3_PATHWAY

COL4A1 COL4A3 COL4A5 L1CAM

5.94e-0543704M53
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A3 COL4A5 COL5A3

6.51e-0544704M27812
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A1 COL4A3 COL4A5 ADAMTS18 COL5A3 KLKB1

6.70e-05140706M587
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A3 COL4A5 ADAMTS3 COL5A3

8.28e-0590705M631
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A3 COL4A5

9.07e-0518703M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A3 COL4A5

9.07e-0518703MM14882
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A3 COL4A5 COL5A3

1.08e-0450704MM14796
PathwayBIOCARTA_AMI_PATHWAY

COL4A1 COL4A3 COL4A5

1.26e-0420703M15394
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A1 COL4A3 COL4A5 COL5A3

1.36e-0453704MM14566
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A3 COL4A5 COL5A3

1.81e-0457704MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A3 COL4A5 COL5A3

1.93e-0458704M2049
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A3

2.07e-0459704M27218
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A3 COL4A5 COL5A3

2.35e-0461704M27103
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A1 COL4A3 COL4A5 COL5A3 KLKB1

2.52e-04114705MM14571
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A1 COL4A3 COL4A5 COL5A3

2.83e-0464704M26953
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS3 ADAMTS18 MUC5B ADAMTSL3

3.57e-0468704M27303
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A3 COL4A5

4.32e-0430703M27216
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A3

5.46e-0476704MM14867
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A1 COL4A3 COL4A5 COL5A3

8.34e-0485704M16441
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS3 ADAMTS18 ADAMTSL3

9.43e-0439703M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS3 ADAMTS18 ADAMTSL3

9.43e-0439703MM15165
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS3 MC2R ADAMTS18 MUC5B ADAMTSL3 ALDOB

1.49e-03250706M27554
PathwayPID_SYNDECAN_1_PATHWAY

COL4A1 COL4A3 COL4A5

1.53e-0346703M198
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A1 COL4A3 COL4A5 ADAMTS3 COL5A3 KLKB1

1.75e-03258706MM14572
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

COL4A1 COL4A3 PLXNA3 COL4A5 MYO9B COL5A3

1.85e-03261706MM15676
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS3 ADAMTS18 MUC5B ADAMTSL3

2.10e-03109704MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS3 ADAMTS18 MUC5B ADAMTSL3

2.24e-03111704M27416
PathwayWP_8P231_COPY_NUMBER_VARIATION_SYNDROME

FCGR2A FDFT1 MTMR9

2.43e-0354703M48073
Pubmed

Identification of an Altered Matrix Signature in Kidney Aging and Disease.

COL4A1 COL4A3 COL4A5

1.91e-08394334049963
Pubmed

Expression of four immunoglobulin superfamily adhesion molecules (L1, Nr-CAM/Bravo, neurofascin/ABGP, and N-CAM) in the developing mouse spinal cord.

NRCAM L1CAM NCAM1

7.63e-0849437706555
Pubmed

A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla.

NRCAM L1CAM NCAM1

1.90e-07594311807022
Pubmed

The Wilms tumor gene, Wt1, maintains testicular cord integrity by regulating the expression of Col4a1 and Col4a2.

COL4A1 COL4A3 COL4A5 NCAM1

2.89e-072194423325811
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A1 COL4A3 COL4A5

3.80e-0769432426947
Pubmed

Expression of connexins in the developing olfactory system of the mouse.

GJA1 L1CAM NCAM1

3.80e-0769431332989
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A1 COL4A3 COL4A5

3.80e-07694310534397
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A1 COL4A3 COL4A5

3.80e-07694319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A1 COL4A3 COL4A5

3.80e-0769436988303
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A1 COL4A3 COL4A5

3.80e-0769439506531
Pubmed

HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.

COL4A1 COL4A3 COL4A5

3.80e-0769437495302
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A1 COL4A3 COL4A5

3.80e-07694323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A1 COL4A3 COL4A5

3.80e-0769436811420
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A1 COL4A3 COL4A5

3.80e-0769436389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A1 COL4A3 COL4A5

3.80e-07694312225806
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A1 COL4A3 COL4A5

3.80e-0769439673377
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A1 COL4A3 COL4A5

3.80e-07694311732842
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A1 COL4A3 COL4A5

6.64e-0779438006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A1 COL4A3 COL4A5

6.64e-07794310416788
Pubmed

Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).

COL4A1 COL4A3 COL4A5

6.64e-07794310716744
Pubmed

Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.

COL4A1 COL4A3 COL4A5

6.64e-0779437521231
Pubmed

Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals.

COL4A1 COL4A3 COL4A5

6.64e-07794317418794
Pubmed

Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.

COL4A1 COL4A3 COL4A5

6.64e-07794310639489
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A1 COL4A3 COL4A5

6.64e-07794311711546
Pubmed

Tails of unconventional myosins.

MYO9A MYO9B MYO15A

6.64e-07794311212352
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A1 COL4A3 COL4A5

6.64e-0779431724753
Pubmed

Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.

COL4A1 COL4A3 COL4A5

1.06e-0689431377218
Pubmed

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.

COL4A1 COL4A3 COL4A5

1.06e-06894310970885
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A1 COL4A3 COL4A5

1.06e-0689433997552
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A1 COL4A3 COL4A5

1.06e-06894329422532
Pubmed

Mice develop normally without tenascin.

COL4A1 COL4A3 COL4A5

1.06e-0689431383086
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A1 COL4A3 COL4A5

1.06e-06894310382266
Pubmed

Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.

COL4A1 COL4A3 COL4A5

1.59e-0699438562707
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A1 COL4A3 COL4A5

1.59e-06994312101409
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A1 COL4A3 COL4A5

1.59e-0699439878537
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

COL4A1 COL4A3 COL4A5

2.26e-06109439415455
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A1 COL4A3 COL4A5

2.26e-06109439136074
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A1 COL4A3 COL4A5

3.11e-06119437500359
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A1 COL4A3 COL4A5

3.11e-061194314998921
Pubmed

Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.

COL4A1 CUL2 COL4A3

3.11e-061194317339318
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A1 COL4A3 COL4A5

3.11e-06119439731539
Pubmed

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

COL4A1 COL4A3 COL4A5

4.13e-06129438918877
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A1 COL4A3 COL4A5

4.13e-061294315837576
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A1 COL4A3 COL4A5

4.13e-061294316024816
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A1 COL4A3 COL4A5

4.13e-061294312180907
Pubmed

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

GJA1 EFEMP1 HECTD4

4.13e-061294319396169
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL4A1 PLXNA3 COL4A5 GJA1 CACNA2D1 FAM234A EFEMP1 HNRNPUL2 FDFT1 XPO6 L1CAM USP48 IL6ST DMXL1

4.22e-061201941435696571
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

COL4A1 COL4A3 COL4A5 SMAD9

4.24e-064094427068110
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

COL4A1 COL4A3 COL4A5

5.36e-06139439833687
Pubmed

Pioneering axons regulate neuronal polarization in the developing cerebral cortex.

NRCAM L1CAM NCAM1

5.36e-061394324559674
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

CACNA2D1 ORM2 NRCAM L1CAM NCAM1 KLKB1 IL6ST

6.57e-0625794716335952
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A1 COL4A3 COL4A5

6.81e-061494312878203
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

COL4A1 ORM2 L1CAM NCAM1 COL5A3

6.86e-069794527559042
Pubmed

Regionally specific expression of L1 and sialylated NCAM in the retinofugal pathway of mouse embryos.

L1CAM NCAM1

7.23e-06294215022265
Pubmed

PUM2 regulates the formation of thoracic aortic dissection through EFEMP1.

EFEMP1 PUM2

7.23e-06294237062520
Pubmed

Neuronal cell adhesion molecule deletion induces a cognitive and behavioral phenotype reflective of impulsivity.

NRCAM NCAM1

7.23e-06294218081712
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

7.23e-06294210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

7.23e-06294216416087
Pubmed

Effect of Cell Adhesion Molecules on the Neurite Outgrowth of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons.

L1CAM NCAM1

7.23e-06294226990843
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

7.23e-06294232081420
Pubmed

Mutation detection of COL4An gene based on mRNA of peripheral blood lymphocytes and prenatal diagnosis of Alport syndrome in China.

COL4A3 COL4A5

7.23e-06294221143337
Pubmed

Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers.

COL4A3 FCGR2A

7.23e-06294223303673
Pubmed

Neural cell adhesion molecule, NCAM, regulates thalamocortical axon pathfinding and the organization of the cortical somatosensory representation in mouse.

L1CAM NCAM1

7.23e-06294222723769
Pubmed

Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb.

L1CAM NCAM1

7.23e-0629421723996
Pubmed

The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth.

L1CAM NCAM1

7.23e-0629428509458
Pubmed

Universal expression of cell adhesion molecule NCAM in neuroblastoma in contrast to L1: implications for different roles in tumor biology of neuroblastoma?

L1CAM NCAM1

7.23e-06294218972120
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

7.23e-0629427524912
Pubmed

Distinct expression patterns of alpha1 (IV) and alpha5 (IV) collagen chains in cylindroma and malignant cylindroma.

COL4A1 COL4A5

7.23e-06294215583824
Pubmed

Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development.

NRCAM L1CAM

7.23e-06294211564762
Pubmed

Functional interaction between TRPC1 channel and connexin-43 protein: a novel pathway underlying S1P action on skeletal myogenesis.

GJA1 TRPC1

7.23e-06294220614160
Pubmed

Association between FCGR2A rs1801274 and MUC5B rs35705950 variations and pneumonia susceptibility.

FCGR2A MUC5B

7.23e-06294232252656
Pubmed

Class IX Myosins: Motorized RhoGAP Signaling Molecules.

MYO9A MYO9B

7.23e-06294232451867
Pubmed

Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome.

COL4A3 COL4A5

7.23e-06294235177655
Pubmed

Prevalence Estimates of Predicted Pathogenic COL4A3-COL4A5 Variants in a Population Sequencing Database and Their Implications for Alport Syndrome.

COL4A3 COL4A5

7.23e-06294234400539
Pubmed

Possible Digenic Disease in a Caucasian Family with COL4A3 and COL4A5 Mutations.

COL4A3 COL4A5

7.23e-06294230661074
Pubmed

L1-CAM and N-CAM: From Adhesion Proteins to Pharmacological Targets.

L1CAM NCAM1

7.23e-06294226478212
Pubmed

Tlr5 is not primarily associated with susceptibility to Salmonella Typhimurium infection in MOLF/Ei mice.

SLC11A1 TLR5

7.23e-06294216688529
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

7.23e-0629429060413
Pubmed

Spectrum of clinical features and type IV collagen alpha-chain distribution in Chinese patients with Alport syndrome.

COL4A3 COL4A5

7.23e-06294216940319
Pubmed

Guidelines for Genetic Testing and Management of Alport Syndrome.

COL4A3 COL4A5

7.23e-06294234930753
Pubmed

Cell adhesion molecules in the early developing mouse retina: retinal neurons show preferential outgrowth in vitro on L1 but not N-CAM.

L1CAM NCAM1

7.23e-0629428071656
Pubmed

Homophilic NCAM interactions interfere with L1 stimulated neurite outgrowth.

L1CAM NCAM1

7.23e-06294210611478
Pubmed

Discordance between skin biopsy and kidney biopsy in an X-linked carrier of Alport syndrome.

COL4A3 COL4A5

7.23e-06294217294221
Pubmed

Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1. Two L1 isoforms in the cytoplasmic region are produced by differential splicing.

L1CAM NCAM1

7.23e-0629421894011
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

COL4A1 COL4A3 COL4A5

8.50e-061594310625553
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

COL4A1 COL4A3 COL4A5

8.50e-06159439264260
Pubmed

Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.

COL4A1 COL4A3 COL4A5

8.50e-061594310706142
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A1 COL4A3 COL4A5

1.04e-051694315878328
Pubmed

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.

COL4A1 COL4A3 COL4A5

1.51e-05189439160753
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

DYM EFEMP1 ADAMTS3 MYO9A MYO9B ADAMTSL3

1.69e-0519894620881960
Pubmed

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.

COL4A1 COL4A3 COL4A5

1.80e-051994315689378
Pubmed

Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome.

COL4A3 COL4A5

2.16e-05394227576055
Pubmed

A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure.

COL4A3 USH2A

2.16e-05394214676276
Pubmed

Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.

COL4A1 COL4A3

2.16e-0539423025878
Pubmed

A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers.

COL4A3 COL4A5

2.16e-05394224522496
Pubmed

The localization and secretion of type IV collagen in synovial capillaries by immunohistochemistry using a monoclonal antibody against human type IV collagen.

COL4A1 COL4A5

2.16e-0539426386565
Pubmed

Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches.

COL4A3 COL4A5

2.16e-0539427962065
Pubmed

Autosomal dominant form of type IV collagen nephropathy exists among patients with hereditary nephritis difficult to diagnose clinicopathologically.

COL4A3 COL4A5

2.16e-05394228704582
Pubmed

Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16+ NK cells as rapid producers of abundant IFN-gamma on activation.

FCGR2A NCAM1

2.16e-05394221187373
Pubmed

Integration of Genetic Testing and Pathology for the Diagnosis of Adults with FSGS.

COL4A3 COL4A5

2.16e-05394230647093
InteractionOSM interactions

COL4A1 COL4A3 COL4A5 IL6ST

1.86e-0620924int:OSM
GeneFamilyMyosins, class IX

MYO9A MYO9B

1.56e-0527221103
GeneFamilyCollagens

COL4A1 COL4A3 COL4A5 COL5A3

3.32e-0546724490
GeneFamilyFibronectin type III domain containing

NRCAM L1CAM NCAM1 USH2A IL6ST

4.42e-04160725555
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

1.59e-0315722418
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS3 ADAMTS18

2.56e-031972250
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

NRCAM L1CAM NCAM1 ADAMTSL3

3.90e-03161724593
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM5D

4.08e-0324722485
GeneFamilyCalcium voltage-gated channel subunits

CACNA1S CACNA2D1

4.78e-0326722253
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_LYMPHATIC_ENDOTHELIAL_CELL

COL4A5 MRC1 GJA1 EFEMP1 FCGR2A SLCO2B1 WASF3 NAV3 ADAMTSL3 KLKB1

1.17e-063829410M45756
CoexpressionHAY_BONE_MARROW_STROMAL

COL4A1 GJA1 CACNA2D1 EFEMP1 WASF3 NAV3 NAV2 COL5A3 ARMCX2 ADAMTSL3 SVEP1 IL6ST SMAD9

3.54e-067679413M39209
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A1 COL4A3 COL4A5 USH2A

1.28e-0540944M5887
CoexpressionNABA_MATRISOME

COL4A1 COL4A3 PLXNA3 COL4A5 EFEMP1 ADAMTS3 ADAM20 ADAMTS18 COL5A3 CST7 MUC5B ADAMTSL3 USH2A SVEP1

1.71e-0510269414M5889
CoexpressionNABA_COLLAGENS

COL4A1 COL4A3 COL4A5 COL5A3

1.72e-0543944MM17060
CoexpressionNABA_COLLAGENS

COL4A1 COL4A3 COL4A5 COL5A3

1.89e-0544944M3005
CoexpressionNABA_CORE_MATRISOME

COL4A1 COL4A3 COL4A5 EFEMP1 COL5A3 USH2A SVEP1

6.10e-05275947M5884
CoexpressionNABA_MATRISOME

COL4A1 COL4A3 PLXNA3 COL4A5 EFEMP1 ADAMTS3 ADAM20 ADAMTS18 COL5A3 CST7 MUC5B ADAMTSL3 SVEP1

6.27e-0510089413MM17056
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A1 COL4A3 COL4A5

7.51e-0523943M48001
CoexpressionGSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN

TPP1 TLR5 HECTD4 CCAR1 IL6ST DMXL1

8.08e-05198946M8624
CoexpressionGSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN

COL4A3 GJA1 DYM TPP1 COL5A3 UBXN2A

8.54e-05200946M7993
CoexpressionHALLMARK_ESTROGEN_RESPONSE_EARLY

GJA1 FDFT1 SCNN1A NAV2 GREB1 IL6ST

8.54e-05200946M5906
CoexpressionAIZARANI_LIVER_C2_KUPFFER_CELLS_1

MRC1 FCGR2A SLCO2B1 TPP1 REL NCOA4

8.54e-05200946M39106
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_INTERMEDIATE_LYMPHATIC_ENDO_CELL

SETD9 COL4A5 MRC1 EFEMP1 FCGR2A WASF3 FAM171B SMAD9

1.01e-04402948M45754
CoexpressionCHEN_METABOLIC_SYNDROM_NETWORK

COL4A1 MRC1 SLC11A1 ADAMTS3 FCGR2A MYO9B SLCO2B1 ACOT9 LRSAM1 L1CAM SCNN1A ARMCX2 KLKB1 SVEP1

1.34e-0412429414M1920
CoexpressionRIGGINS_TAMOXIFEN_RESISTANCE_DN

GJA1 NRCAM SCNN1A FRYL GREB1 IL6ST

1.47e-04221946M15835
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500

FDFT1 L1CAM HECTD4 NCAM1 FAM171B LONRF2

1.74e-05125926gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_500
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000

NRCAM FDFT1 L1CAM HECTD4 NCAM1 FAM171B LONRF2

3.71e-05211927gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_1000
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CACNA2D1 ADAMTS3 NAV3 ABCC9 GREB1 ADAMTSL3 SVEP1 IL6ST

5.08e-0918493867164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA2D1 EFEMP1 NAV3 NAV2 ABCC9 GREB1 ADAMTSL3 SVEP1

5.31e-09185938a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA2D1 EFEMP1 ADAMTS3 TRPC1 NAV3 GREB1 ADAMTSL3 SVEP1

6.54e-091909387dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A1 GJA1 CACNA2D1 NRCAM TRPC1 L1CAM NAV3

8.54e-08175937f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 HOXA6 CACNA2D1 NRCAM ABCC9 COL5A3 ADAMTSL3

9.96e-08179937dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 EFEMP1 MYO1D MYO9A SCNN1A NAV2

1.07e-07181937b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A1 COL4A3 COL4A5 MYO1D WASF3 SCNN1A NAV2

1.20e-0718493757c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A1 COL4A3 COL4A5 MYO1D WASF3 SCNN1A NAV2

1.20e-07184937d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 EFEMP1 MYO1D MYO9A SCNN1A NAV2

1.29e-071869373aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MRC1 EFEMP1 FCGR2A SLCO2B1 TLR5 NCAM1 ADAMTSL3

1.49e-071909379ce301841ce9486701fa28eb2a9929e35d476878
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A1 ADAMTS3 NAV3 NAV2 COL5A3 ADAMTSL3 SVEP1

1.66e-07193937261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EFEMP1 ADAMTS3 NAV3 NAV2 ABCC9 ADAMTSL3 SVEP1

1.72e-07194937c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EFEMP1 ADAMTS3 NAV3 NAV2 ABCC9 ADAMTSL3 SVEP1

1.78e-071959373c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A5 EFEMP1 SLCO2B1 NAV3 ABCC9 ADAMTSL3

1.85e-071969376bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A5 EFEMP1 SLCO2B1 NAV3 ABCC9 ADAMTSL3

1.85e-07196937c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRC1 SLC11A1 FCGR2A MYO9B SLCO2B1 TPP1 REL

1.85e-071969375fe6534af65d43eeacd4b031310242b4f706008b
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 HOXA6 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

2.05e-07199937000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A1 EFEMP1 NAV3 NAV2 ABCC9 ADAMTSL3 SVEP1

2.12e-072009370c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 GJA1 DNAI1 NAV3 PKDREJ USP6NL

1.39e-06167936961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 GJA1 DNAI1 NAV3 PKDREJ USP6NL

1.39e-061679363760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 GJA1 SCNN1A NAV2 SMAD9

1.71e-061739363afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 MYO9A SLCO2B1 SCNN1A NAV2

1.95e-061779369af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 NAV3 ABCC9 GREB1 ADAMTSL3 SVEP1

2.30e-061829363dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellNS-critical-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A1 GJA1 NRCAM L1CAM NAV3 NCAM1

2.30e-06182936dd1c59babf7211362452e3e264009d70004d99f6
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GJA1 SLC11A1 NRCAM FCGR2A MYO9B CST7

2.37e-06183936278064c9f0582463b83bf156d34e77f60187613b
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 MRC1 GJA1 DNAI1 ARMCX2 IL6ST

2.52e-06185936742350093d90f96735dc73e3360cdd749bae63fd
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

COL4A1 CACNA2D1 NAV3 ABCC9 COL5A3 ADAMTSL3

2.60e-06186936cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 MYO1D MYO9A SCNN1A NAV2

2.69e-0618793658d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

COL4A1 COL4A3 COL4A5 MYO1D WASF3 SCNN1A

2.69e-0618793677f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

CACNA2D1 ADAMTS3 NAV3 GREB1 ADAMTSL3 SVEP1

2.77e-06188936706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFEMP1 NRCAM ABCC9 NCAM1 ARMCX2 SVEP1

2.86e-06189936a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

COL4A1 MRC1 SLCO2B1 ABCC9 ALDOB IL6ST

2.86e-061899369a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFEMP1 NRCAM ABCC9 NCAM1 ARMCX2 SVEP1

2.86e-06189936381058f55908f84375b54601d617389ef43ab855
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFEMP1 NRCAM ABCC9 NCAM1 ARMCX2 SVEP1

2.86e-06189936302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 WASF3 NAV2 ABCC9 NCAM1 SVEP1

2.86e-06189936c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 CACNA2D1 NAV2 ABCC9 SVEP1 IL6ST

2.94e-061909361121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 CACNA2D1 NAV2 ABCC9 SVEP1 IL6ST

2.94e-06190936048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 NAV3 ABCC9 NCAM1 ADAMTSL3 SVEP1

2.94e-06190936efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

MRC1 SLC11A1 FCGR2A MYO9B SLCO2B1 REL

2.94e-06190936d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 WASF3 NAV2 ABCC9 NCAM1 SVEP1

3.03e-06191936c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

COL4A3 GJA1 EFEMP1 WASF3 SCNN1A NAV2

3.03e-0619193666875b2ec2c510489407f3e433a90cdf74a15094
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 WASF3 NAV2 ABCC9 NCAM1 SVEP1

3.03e-06191936806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 WASF3 NAV2 ABCC9 NCAM1 SVEP1

3.03e-06191936cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A1 COL4A3 WASF3 COL5A3 ADAMTSL3 SVEP1

3.03e-0619193670c067c54084bfb02c29bab085f4defd477194fb
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL4A1 CACNA2D1 EFEMP1 ABCC9 COL5A3 ADAMTSL3

3.03e-0619193678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL4A1 COL4A3 WASF3 COL5A3 ADAMTSL3 SVEP1

3.13e-06192936356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 HOXA6 EFEMP1 NRCAM COL5A3 ADAMTSL3

3.22e-06193936b2abe939027a69b60d83a28d4d4cc53ba1dee4c5
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 HOXA6 EFEMP1 NRCAM COL5A3 ADAMTSL3

3.22e-0619393687ce81ff5b27d9c4300826d76ff5a62e9c408d5d
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 HOXA6 EFEMP1 NRCAM COL5A3 ADAMTSL3

3.22e-06193936d75f334fe3d9f39ef02a5de0f8202f7a761a8fc8
ToppCellEC-Sinusoidal_ECs|EC / Lineage and Cell class

COL4A1 MRC1 GJA1 ABCC9 ALDOB IL6ST

3.22e-061939361291b1d3494dcb4b9309f8bff63fb662e7eca0c8
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL4A1 COL4A3 WASF3 COL5A3 ADAMTSL3 SVEP1

3.22e-06193936dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 HOXA6 EFEMP1 NRCAM COL5A3 ADAMTSL3

3.22e-0619393641ea268e7697101fe70d8ef1045f3a43b9311739
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 HOXA6 EFEMP1 NRCAM COL5A3 ADAMTSL3

3.32e-061949363cffb5c58f6d5bd254f39ee9c41b7e1e4da0ff75
ToppCell3'-Distal_airway-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 HOXA6 EFEMP1 NRCAM COL5A3 ADAMTSL3

3.32e-06194936f5e3e675187afb6efa774f2a8d685efcf813de82
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

MRC1 SLC11A1 FCGR2A MYO9B SLCO2B1 REL

3.52e-061969364929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLC6A4 COL4A3 GJA1 EFEMP1 SCNN1A NAV2

3.63e-061979369ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCellFetal_29-31_weeks-Immune|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MRC1 SLC11A1 FCGR2A MYO9B SLCO2B1 REL

3.73e-061989365dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

COL4A1 SLC6A4 COL4A3 GJA1 EFEMP1 NAV2

3.73e-061989360047a9ef7684230ac5179efea94461480e90bdaf
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A3 EFEMP1 MYO1D MYO9A SCNN1A NAV2

3.84e-06199936d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A5 GJA1 EFEMP1 SCNN1A NAV2

3.84e-06199936c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MRC1 SLC11A1 FCGR2A MYO9B SLCO2B1 TPP1

3.84e-0619993622001aa733273e784051b7f750e07d99aaf7a225
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MRC1 SLC11A1 FCGR2A SLCO2B1 TLR5 IL6ST

3.84e-061999364ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MRC1 SLC11A1 FCGR2A SLCO2B1 TLR5 IL6ST

3.84e-061999363ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCellmedial-mesenchymal-Pericyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

3.96e-06200936bbda454260016be92b539e220ecf7bcbbc6139e4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC11A1 FCGR2A SLCO2B1 TPP1 TLR5 IL6ST

3.96e-062009360eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

3.96e-06200936911db29f254bb697610e720ba78816e2c7f57933
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC11A1 FCGR2A SLCO2B1 TPP1 TLR5 IL6ST

3.96e-0620093601d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

COL4A3 COL4A5 EFEMP1 MYO9A SCNN1A NAV2

3.96e-062009362dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellmedial-mesenchymal-Pericyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

3.96e-06200936f36d7cb6345daccebf76997f998e35d959b59452
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL4A3 EFEMP1 MYO1D MYO9A SCNN1A NAV2

3.96e-06200936ddfb1f006365bf16203ee49f20200f68220cc288
ToppCelldistal-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A5 GJA1 EFEMP1 SCNN1A NAV2

3.96e-06200936313ec1e53bd738a9cb48dc5b946261156f99f44b
ToppCelldistal-mesenchymal-Pericyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

3.96e-06200936fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL4A3 EFEMP1 MYO1D MYO9A SCNN1A NAV2

3.96e-062009368683445ad5b70748c4a1f12eb77d47623085147e
ToppCellmedial-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

3.96e-062009369820fb4f6efcdfc6de937ef2302a98b48426baa3
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A1 EFEMP1 NAV3 NAV2 ADAMTSL3 SVEP1

3.96e-06200936b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellBiopsy_Other_PF-Epithelial-AT1|Biopsy_Other_PF / Sample group, Lineage and Cell type

COL4A3 COL4A5 GJA1 EFEMP1 WASF3 SCNN1A

3.96e-06200936b746dcc94814bcbca63c71e6451a9c5f084bcfaf
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

3.96e-06200936867935701fac71a3fe01578362da0676f959736c
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

COL4A1 EFEMP1 ADAMTS18 ABCC9 COL5A3 ADAMTSL3

3.96e-0620093669edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellBiopsy_Control_(H.)-Epithelial-AT1|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

COL4A1 COL4A3 GJA1 EFEMP1 WASF3 SCNN1A

3.96e-062009363a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCelldistal-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A1 EFEMP1 NRCAM ABCC9 COL5A3 ADAMTSL3

3.96e-062009364ee0b2f56c2652435fa78bf6b3c90cea28df74e0
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 SLC6A4 COL4A3 GJA1 ABCC9

1.85e-05155935010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

COL4A1 GJA1 NRCAM SLCO2B1 ADAMTS18

2.09e-051599354f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|343B / Donor, Lineage, Cell class and subclass (all cells)

MRC1 SLC11A1 FCGR2A SLCO2B1 KLKB1

2.29e-051629350acb8f7b51bf422d4f4f8e99bd10360163ae4eb7
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL4A5 GJA1 EFEMP1 MC2R SVEP1

2.73e-051689359930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 SLC11A1 SLCO2B1 LONRF2 GPR160

2.80e-05169935a1efc20e34a81ae32f8d278a5486811ade03ef24
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|390C / Donor, Lineage, Cell class and subclass (all cells)

MRC1 SLC11A1 FCGR2A MYO9B SLCO2B1

2.88e-05170935439167e44a1bd5ac8e1e457351dd202ec968db46
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

COL4A1 CACNA2D1 NRCAM COL5A3 ADAMTSL3

2.97e-05171935080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 ABCC9 ATP13A5 PKDREJ

3.05e-05859347c5ea38893372fdecf7cc3ccf46a37b4ec45f0b1
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 ABCC9 ATP13A5 PKDREJ

3.05e-05859345a2c02aeceeabd44a417b09ac8b2e2f185070b15
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

COL4A3 ABCC9 ATP13A5 PKDREJ

3.05e-05859340bfabb6761a84d6a04f9fa415106a33059d78099
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC6A4 SLC6A11 NCAM1 CST7 KDM5D

3.05e-0517293568fd03f2c8ee01fe46194400f74ede3830e00f34
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

GJA1 CACNA2D1 EFEMP1 TRPC1 ADAMTSL3

3.05e-05172935d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

COL4A1 NRCAM COL5A3 ADAMTSL3 CHRND

3.05e-05172935858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRC1 SLC11A1 FCGR2A MYO9B SLCO2B1

3.22e-05174935d5c22b43531414951666ee7542a66ed9380e2d14
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A3 GJA1 WASF3 SCNN1A

3.31e-05175935bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 EFEMP1 COL5A3 ADAMTSL3 SVEP1

3.40e-05176935fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 SLC6A4 COL4A3 GJA1 WASF3

3.40e-051769354a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 EFEMP1 COL5A3 ADAMTSL3 SVEP1

3.40e-05176935f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 ABCC9 COL5A3 LONRF2 ADAMTSL3

3.50e-05177935bd602db857f37869ef76d14c05ef522c509f08ee
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

COL4A1 SLC6A4 GJA1 NRCAM FAM171B

3.50e-05177935f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
DrugAC1NPPZW

COL4A3 COL4A5 GJA1 TRPC1 SCNN1A NAV3 NAV2

2.17e-07103937CID005183170
DrugS-(-)-Etomoxir

DYM MYO1D MYO9A MYO9B FDFT1 MYO15A

3.45e-06100936CID000060765
DrugBenzethonium chloride [121-54-0]; Up 200; 9uM; HL60; HT_HG-U133A

HOXA6 CACNA1S ORM2 SLC11A1 SCNN1A ALDOB USP6NL

1.54e-051959372508_UP
Drugsipatrigine

SLC6A4 SLC6A11 CACNA2D1 SCNN1A

1.55e-0537934CID000060803
Drugfurosemide

SLC6A4 SLC6A11 CACNA2D1 ORM2 FCGR2A MC2R SCNN1A KLKB1

1.59e-05272938CID000003440
DrugSM-6586

CACNA1S CACNA2D1

1.65e-052932CID005487142
Drugdiazipine

CACNA1S CACNA2D1

1.65e-052932CID000195792
DrugNabumetone [42924-53-8]; Up 200; 17.6uM; MCF7; HT_HG-U133A

COL4A1 SLC11A1 TPP1 GREB1 MYO15A SVEP1 SMAD9

1.70e-051989376487_UP
Diseasecollagen disease (implicated_via_orthology)

COL4A1 COL4A3 COL4A5 TLR5

3.93e-0812904DOID:854 (implicated_via_orthology)
DiseaseAlport syndrome (is_implicated_in)

COL4A3 COL4A5

2.75e-053902DOID:10983 (is_implicated_in)
DiseaseAlport syndrome

COL4A3 COL4A5

2.75e-053902cv:C1567741
Diseaseadenoma (is_marker_for)

EFEMP1 NCAM1

2.75e-053902DOID:657 (is_marker_for)
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A5

2.75e-053902cv:CN076135
Diseasesystemic lupus erythematosus (is_implicated_in)

SLC11A1 FCGR2A TLR5 KLKB1

3.94e-0562904DOID:9074 (is_implicated_in)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

5.50e-054902DOID:0060809 (implicated_via_orthology)
DiseaseHematuria, Benign Familial

COL4A3 COL4A5

5.50e-054902C0241908
DiseaseAlport Syndrome

COL4A3 COL4A5

5.50e-054902C1567741
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A5

9.15e-055902C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A5

9.15e-055902C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A5

9.15e-055902C1567744
Diseaseautism spectrum disorder (implicated_via_orthology)

SLC6A4 NRCAM KDM5C TRPC1 KDM5D

1.05e-04152905DOID:0060041 (implicated_via_orthology)
DiseaseMarijuana Abuse

SLC6A4 FDFT1 NCAM1

1.05e-0430903C0024809
Diseasedengue hemorrhagic fever (is_implicated_in)

SLC6A4 FCGR2A

1.37e-046902DOID:12206 (is_implicated_in)
DiseaseMASA syndrome (implicated_via_orthology)

NRCAM L1CAM

1.91e-047902DOID:0060246 (implicated_via_orthology)
Diseasecorpus callosum anterior volume measurement

NAV3 NAV2 FAM171B

2.32e-0439903EFO_0010295
DiseasePulmonary Cystic Fibrosis

FCGR2A SCNN1A

3.27e-049902C0392164
DiseaseFibrocystic Disease of Pancreas

FCGR2A SCNN1A

3.27e-049902C1527396
DiseaseHematuria

COL4A1 COL4A5

3.27e-049902C0018965
Diseasemyopathy (implicated_via_orthology)

COL4A1 COL4A3 COL4A5

4.30e-0448903DOID:423 (implicated_via_orthology)
DiseaseSystemic lupus erythematosus

FCGR2A TLR5

4.97e-0411902cv:C0024141
DiseaseShortened QT interval

CACNA2D1 ABCC9

4.97e-0411902C0151879
DiseaseCystic Fibrosis

FCGR2A SCNN1A

4.97e-0411902C0010674
DiseaseProstatic Neoplasms

GJA1 TPP1 WASF3 TLR5 MC2R COL5A3 GREB1 IL6ST

5.95e-04616908C0033578
DiseaseMalignant neoplasm of prostate

GJA1 TPP1 WASF3 TLR5 MC2R COL5A3 GREB1 IL6ST

5.95e-04616908C0376358
Diseaseacylcarnitine measurement

SLC6A11 UBXN2A USH2A USP6NL

6.28e-04127904EFO_0005059
Diseaselow density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor

NCAM1 USP6NL

9.41e-0415902EFO_0004611, EFO_0005658
Diseasediastolic blood pressure, systolic blood pressure

COL4A1 MRC1 GJA1 EFEMP1 ADAMTS3 MYO9A COL5A3 ADAMTSL3

1.02e-03670908EFO_0006335, EFO_0006336
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

1.07e-0316902DOID:0050888 (implicated_via_orthology)
Diseaseulcerative colitis (is_implicated_in)

SLC11A1 FCGR2A

1.21e-0317902DOID:8577 (is_implicated_in)
DiseaseAutistic Disorder

SLC6A4 GJA1 NRCAM MYO1D KDM5C

1.24e-03261905C0004352
Diseaselupus nephritis (is_implicated_in)

FCGR2A KLKB1

1.36e-0318902DOID:0080162 (is_implicated_in)
Diseaseborna disease (biomarker_via_orthology)

SLC6A4 GJA1

1.36e-0318902DOID:5154 (biomarker_via_orthology)
Diseasespine bone size

DYM ADAMTSL3

1.36e-0318902EFO_0004508
DiseaseColorectal Carcinoma

EFEMP1 NRCAM CCAR1 ADAMTS18 LONRF2 ADAMTSL3 IL6ST SMAD9

1.38e-03702908C0009402
DiseaseCongenital Myasthenic Syndromes, Presynaptic

MYO9A CHRND

1.52e-0319902C0751884
Diseasealpha-tocopherol measurement

CACNA2D1 USH2A

1.69e-0320902EFO_0007898
DiseaseLung diseases

DNAI1 SCNN1A SMAD9

1.77e-0378903C0024115
DiseaseArthrogryposis

MYO9A L1CAM

1.86e-0321902C0003886
Diseasepulmonary hypertension (biomarker_via_orthology)

COL4A1 GJA1 SMAD9

1.90e-0380903DOID:6432 (biomarker_via_orthology)
DiseaseRheumatoid Arthritis

SLC11A1 FCGR2A REL IL6ST

2.01e-03174904C0003873
DiseaseBronchiectasis

DNAI1 SCNN1A

2.04e-0322902C0006267
DiseaseRenal glomerular disease

COL4A3 COL4A5

2.23e-0323902C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A5

2.23e-0323902C4521256
Diseasefrailty measurement

SLC6A4 NCAM1

2.23e-0323902EFO_0009885
Diseasethalamus volume

NAV2 NCAM1 CAMTA1

2.26e-0385903EFO_0006935
DiseaseAnhedonia

SLC6A4 GJA1

2.43e-0324902C0178417
DiseaseBrugada Syndrome (disorder)

CACNA2D1 ABCC9

2.43e-0324902C1142166
DiseaseIntellectual Disability

ZCCHC8 ACOT9 FDFT1 TPP1 KDM5C WDR45B

2.49e-03447906C3714756
Diseasecortical surface area measurement

CACNA2D1 ADAMTS3 MYO9B NAV3 NAV2 CCAR1 ADAMTS18 NCAM1 FRYL ADAMTSL3 SVEP1

2.60e-0313459011EFO_0010736
DiseaseCardiac Arrhythmia

GJA1 CACNA2D1

2.64e-0325902C0003811
Diseasevisual epilepsy (biomarker_via_orthology)

GJA1 SLC6A11 IL6ST

2.66e-0390903DOID:11832 (biomarker_via_orthology)
Diseasemacula measurement

COL4A3 MYO9A NAV2 NCAM1

2.71e-03189904EFO_0008375
DiseaseHypertensive disease

GJA1 CACNA2D1 MC2R SCNN1A

2.77e-03190904C0020538

Protein segments in the cluster

PeptideGeneStartEntry
LYKNTNSSNNFSRSC

FAM234A

111

Q9H0X4
ENNNDGSFQISYSCN

CHRND

116

Q07001
GTFAAQENCFQYLQQ

BRAT1

81

Q6PJG6
QYSECFLANQSNFST

ATP13A5

1006

Q4VNC0
QEASNNYSCLFDQIS

CAMTA1

896

Q9Y6Y1
NVNDVCNFASRNDYS

COL4A3

1506

Q01955
QQAAAAAAALQQQYS

CCAR1

71

Q8IX12
ASQSCYQEINTQGNR

ADAM20

526

O43506
ENANALARYASICQQ

ALDOB

166

P05062
RFKANNNDSGEYTCQ

FCGR2A

91

P12318
REYQTRQNQCFYNSS

ORM2

81

P19652
RQNQCFYNSSYLNVQ

ORM2

86

P19652
FLSSQVCFTQNNYIQ

ACOT9

356

Q9Y305
SSYNINDGVLQNSCF

ABCC9

11

O60706
QFNFSERASQTYNNP

DNAI1

191

Q9UI46
FSQKYQACRANLQST

DMXL1

926

Q9Y485
LSNNANYSCNQETIR

ARMCX2

411

Q7L311
QQCFYQGFIRNDSSS

ADAMTS18

141

Q8TE60
NSLDFRAQQCAEYNS

ADAMTS18

646

Q8TE60
NINNVCNFASRNDYS

COL4A1

1506

P02462
LCGNFNQNQADDFTA

MUC5B

561

Q9HC84
FDYNSQQQLFQRTNA

PUM2

256

Q8TB72
DNSYAFNQRSTCNGI

KBTBD3

6

Q8NAB2
QAARYSVEKFNNCTN

CST7

51

O76096
CFYQQSNSVLACNRA

HOXA6

56

P31267
DLTQNVQYNQNRFLC

GREB1

1726

Q4ZG55
NVQERSSAVYQCNAS

NRCAM

421

Q92823
FQQRCAQSAYCNTKQ

MTMR9

376

Q96QG7
YESQRQNLVQQACSS

LRSAM1

406

Q6UWE0
SFNSFEQLCINYANE

MYO15A

1596

Q9UKN7
NQGYNFAEAVNFCTA

KDM5D

596

Q9BY66
AIATLAACYNNQQVF

FDFT1

296

P37268
RFNSSSVQCQNASYS

PLXNA3

736

P51805
QYLANLAEQCSADNN

NAV3

2101

Q8IVL0
AIANVFQNRDYQCDT

FRYL

1191

O94915
RNFILDQCNVYNSGQ

HNRNPUL2

531

Q1KMD3
DTGRYFCLAANDQNN

L1CAM

491

P32004
YQKTNQAAFNICANS

SLC11A1

311

P49279
NYEQALQDASAACQN

LONRF2

246

Q1L5Z9
QNCSATDLFYQGNSQ

HECTD4

2516

Q9Y4D8
LYKQNSISFNACAAQ

OR8U9

86

P0C7N5
SENCSFQYQLRQTNQ

GPR160

6

Q9UJ42
NSQTSSRACNFFNNV

NCOA4

236

Q13772
QCQQRNSHFEYQNTK

ADAMTS3

616

O15072
RQQYFKQNCSQHESS

IL6ST

811

P40189
NFNSLYTALCEQQTS

DYM

331

Q7RTS9
LARANTNNANANVAY

CACNA1S

1656

Q13698
FEQLLNYNVSRANCN

CACNA2D1

341

P54289
CNINNVCNFASRNDY

COL4A5

1521

P29400
GDRNNSSCRNYNKQA

GJA1

291

P17302
QEASNLLQESNCSQY

CUL2

221

Q13617
NNHSLTDVCFSYRNN

MBTPS2

336

O43462
CTNNIRCQFFSYATQ

KLKB1

141

P03952
FQLCNQNKSDCFYQT

SCNN1A

226

P37088
ACRFNQVSCNQANYS

SCNN1A

281

P37088
ATARQNFTYSCQNAA

COL5A3

1641

P25940
DVSFLSVNQNNYSRN

FAM171B

466

Q6P995
AEANQTCNNENAYLT

MRC1

526

P22897
SNQCAQQCYNILGSF

EFEMP1

261

Q12805
RQCNQCQNGFYNLQE

USH2A

671

O75445
QVDQNCVRNSYDVFS

UVRAG

181

Q9P2Y5
YCVSAFQNTEFSNNR

PKDREJ

2131

Q9NTG1
RQYLSNLADQCNSEN

NAV2

2201

Q8IVL1
VGQYVNNCSNDRAAN

SETD9

226

Q8NE22
NNCSNDRAANVCYQE

SETD9

231

Q8NE22
RGSQAANIYCINFNQ

WDR45B

226

Q5MNZ6
NGYFIQNTCNNHFNA

SVEP1

386

Q4LDE5
SDSSIFVQSRNCNYQ

SMAD9

351

O15198
NSYENINNTARNNSD

MC2R

6

Q01718
ENDFGNYNCTAVNRI

NCAM1

481

P13591
YNQKEFVSQSNCQQF

TRPC1

316

P48995
AFISNSRNYFSQCQA

TTLL8

316

A6PVC2
SRQYNHAAANQNSNA

USP6NL

461

Q92738
ACGEANNQNFQQRYH

ZCCHC8

261

Q6NZY4
VTYNDNCENAASQAS

TMPRSS11B

56

Q86T26
QDALDNSQVFYTNCS

SLCO2B1

526

O94956
EFNATDALRCVNNYQ

TIPRL

66

O75663
NYYNASVSCCKQRNN

STPG1

151

Q5TH74
FNEANNFYIRANSLQ

WASF3

56

Q9UPY6
GNNQQSNCEYFVDSL

UBXN2A

26

P68543
CLTALGSYNNYNNNC

SLC6A11

316

P48066
NASNACIYNNADDIV

REL

456

Q04864
VLNSFQDSNNSYARQ

ZSCAN4

46

Q8NAM6
YNCNQCGEAFSQKSN

ZNF782

646

Q6ZMW2
AQYCSEVHRQNTQQF

XPO6

636

Q96QU8
DTQYSDQNRFNLCFE

TLR5

716

O60602
QSHNACVNYANRNAT

SFXN5

141

Q8TD22
NKFNNNCYQDALVTS

SLC6A4

351

P31645
NRYFCENCQSKQNAT

USP48

266

Q86UV5
CNFQLTQYQISHANQ

ZNF781

16

Q8N8C0
FDDNQCGNVFRNTQS

ZNF300

241

Q96RE9
EAFQSGQNNYSCTQC

ZNF17

181

P17021
SNNSQACAQFLEQYF

TPP1

221

O14773
RAQQCSAYNDVQYQG

ADAMTSL3

131

P82987
NQGYNFAEAVNFCTA

KDM5C

606

P41229
DNNSFEQFCINYCNE

MYO1D

391

O94832
NNSFEQFCINFANER

MYO9A

546

B2RTY4
SFEQFCINYANEQLQ

MYO9B

531

Q13459