Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THSD4 FRAS1 VTN COL6A5 MEPE VCAN FGA NID1 MUC4

1.83e-051881579GO:0005201
GeneOntologyMolecularFunctioncell adhesion molecule binding

FLNB VTN CDHR5 ITGA2 ITGB6 PTPN11 TJP1 PTPRZ1 CGN CD40LG FGA IZUMO1 BCAM CNTN2 CDH13

7.91e-0559915715GO:0050839
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RANBP2 RGPD8 RGPD1 RGPD5

1.53e-05201604GO:0006607
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RANBP2 RGPD8 RGPD1

3.72e-0591603GO:0033133
GeneOntologyBiologicalProcesscell morphogenesis

FLNB PLOD3 ALS2 ZSWIM6 SLC30A1 JMJD1C ITGB6 ANKRD27 WDR47 YTHDF1 PTPN11 KIDINS220 PTPRZ1 TET1 CGN CAPRIN2 LRP6 CFAP70 POTEJ CNTN2 CDH13 TBCE SMAD4

5.00e-05119416023GO:0000902
GeneOntologyBiologicalProcesscell-matrix adhesion

VTN ITGA2 ITGB6 PTPN11 FGA NID1 BCAM MUC4 CNTN2 CDH13

5.08e-0527016010GO:0007160
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RANBP2 RGPD8 RGPD1

5.28e-05101603GO:1903301
GeneOntologyCellularComponentnuclear inclusion body

RANBP2 RGPD8 RGPD1 ATXN1

1.39e-05201584GO:0042405
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RANBP2 RGPD8 RGPD1

2.31e-0581583GO:1990723
GeneOntologyCellularComponentextracellular matrix

THSD4 FRAS1 IL16 VTN PLOD3 COL6A5 MEPE OTOGL PTPRZ1 SULF1 VCAN FGA NID1 BCAM MUC4 CDH13

3.90e-0565615816GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

THSD4 FRAS1 IL16 VTN PLOD3 COL6A5 MEPE OTOGL PTPRZ1 SULF1 VCAN FGA NID1 BCAM MUC4 CDH13

4.04e-0565815816GO:0030312
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RANBP2 RGPD8 RGPD1

4.89e-05101583GO:0044614
GeneOntologyCellularComponentcollagen-containing extracellular matrix

THSD4 FRAS1 IL16 VTN PLOD3 COL6A5 PTPRZ1 SULF1 VCAN FGA NID1 BCAM MUC4 CDH13

5.20e-0553015814GO:0062023
GeneOntologyCellularComponentprotein complex involved in cell adhesion

VTN ITGA2 ITGB6 IZUMO1 NID1

8.34e-05591585GO:0098636
GeneOntologyCellularComponentannulate lamellae

RANBP2 RGPD8 RGPD1

1.45e-04141583GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RANBP2 RGPD8 RGPD1

3.18e-04181583GO:0044615
GeneOntologyCellularComponentSUMO ligase complex

RANBP2 RGPD8 RGPD1

5.10e-04211583GO:0106068
GeneOntologyCellularComponentnuclear pore

RANBP2 RGPD8 RGPD1 POM121L2 RGPD5

1.02e-031011585GO:0005643
DomainRan_BP1

RANBP2 RGPD8 RGPD1 RGPD5

2.37e-06121594PF00638
DomainRANBD1

RANBP2 RGPD8 RGPD1 RGPD5

2.37e-06121594PS50196
DomainRanBD

RANBP2 RGPD8 RGPD1 RGPD5

3.41e-06131594SM00160
DomainRan_bind_dom

RANBP2 RGPD8 RGPD1 RGPD5

3.41e-06131594IPR000156
DomainGrip

RGPD8 RGPD1 RGPD5

9.50e-05111593SM00755
DomainGRIP

RGPD8 RGPD1 RGPD5

9.50e-05111593PF01465
DomainGRIP_dom

RGPD8 RGPD1 RGPD5

1.26e-04121593IPR000237
DomainGRIP

RGPD8 RGPD1 RGPD5

1.26e-04121593PS50913
DomainZU5

MACC1 ANK1 TJP1

1.26e-04121593PF00791
DomainZU5_dom

MACC1 ANK1 TJP1

1.26e-04121593IPR000906
DomainDUF4211

PRR12 QSER1

2.15e-0431592PF13926
DomainDUF4211

PRR12 QSER1

2.15e-0431592IPR025451
DomainWD40

WSB2 WDFY4 EML3 WDR53 SHKBP1 WDR47 WDR97 KCTD3 WDR90

4.93e-042681599SM00320
DomainWD40_repeat_CS

WSB2 WDFY4 WDR53 WDR47 WDR97 KCTD3 WDR90

5.17e-041641597IPR019775
DomainWD40_repeat

WSB2 WDFY4 EML3 WDR53 SHKBP1 WDR47 WDR97 KCTD3 WDR90

5.49e-042721599IPR001680
DomainWD_REPEATS_1

WSB2 WDFY4 EML3 WDR53 SHKBP1 WDR47 WDR97 KCTD3 WDR90

6.42e-042781599PS00678
DomainWD_REPEATS_2

WSB2 WDFY4 EML3 WDR53 SHKBP1 WDR47 WDR97 KCTD3 WDR90

6.58e-042791599PS50082
DomainWD_REPEATS_REGION

WSB2 WDFY4 EML3 WDR53 SHKBP1 WDR47 WDR97 KCTD3 WDR90

6.58e-042791599PS50294
DomainNIDO_dom

NID1 MUC4

7.08e-0451592IPR003886
DomainNIDO

NID1 MUC4

7.08e-0451592SM00539
DomainNIDO

NID1 MUC4

7.08e-0451592PF06119
DomainNIDO

NID1 MUC4

7.08e-0451592PS51220
PathwayBIOCARTA_RANBP2_PATHWAY

RANBP2 HDAC5 RGPD8 RGPD1

9.87e-06181104MM1549
PathwayREACTOME_ECM_PROTEOGLYCANS

VTN COL6A5 ITGA2 ITGB6 VCAN

3.12e-05471105MM14925
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B ZHX3 FRAS1 HDAC5 LRCH2 SPEG GON4L ALS2 ZSWIM6 WDR47 KIDINS220 STARD9 NFAT5

8.51e-084071651312693553
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

4.18e-07416539480752
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNB RANBP2 NDUFS7 HDAC5 RGPD8 RGPD1 IDH3A JMJD1C PRR12 N4BP2 TET1 TAF1

8.39e-074181651234709266
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FRAS1 IL16 VTN PLOD3 COL6A5 VCAN FGA NID1

1.45e-06167165822159717
Pubmed

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.

VTA1 PTPN11 IZUMO1 FUT2

1.79e-0619165421060863
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RANBP2 RGPD8 RGPD1

3.62e-06716539037092
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD8 RGPD1 RGPD5

3.62e-067165315710750
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RANBP2 RGPD8 RGPD1

3.62e-067165311353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RANBP2 RGPD8 RGPD1

3.62e-067165330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RANBP2 RGPD8 RGPD1

3.62e-067165338838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RANBP2 RGPD8 RGPD1

3.62e-06716537559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RANBP2 RGPD8 RGPD1

3.62e-067165317372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RANBP2 RGPD8 RGPD1

3.62e-067165338657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RANBP2 RGPD8 RGPD1

3.62e-067165321205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RANBP2 RGPD8 RGPD1

3.62e-067165318949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RANBP2 RGPD8 RGPD1

3.62e-067165325187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RANBP2 RGPD8 RGPD1

3.62e-06716538603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RANBP2 RGPD8 RGPD1

3.62e-067165326632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RANBP2 RGPD8 RGPD1

3.62e-067165324403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RANBP2 RGPD8 RGPD1

3.62e-067165323818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RANBP2 RGPD8 RGPD1

3.62e-067165323536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RANBP2 RGPD8 RGPD1

3.62e-067165312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RANBP2 RGPD8 RGPD1

3.62e-067165322821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RANBP2 RGPD8 RGPD1

3.62e-067165320682751
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CELF5 ZHX3 PLOD3 ANK1 SPEG SCAF4 GTF2F2 FGA NID1 IGLL1 MUC4 HYDIN

4.98e-064971651236774506
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

HDAC5 GON4L ITGA2 SIRT6 CPS1 MAST2 EML3 SDR39U1 NCOA5 PTPN11 TJP1 SULF1 VCAN CGN FGA CPXM1 NID1 CNTN2 CDH13

5.57e-0612151651915146197
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RANBP2 RGPD8 RGPD1

5.77e-068165321670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RANBP2 RGPD8 RGPD1

5.77e-068165327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RANBP2 RGPD8 RGPD1

5.77e-068165321310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RANBP2 RGPD8 RGPD1

5.77e-068165322262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RANBP2 RGPD8 RGPD1

5.77e-068165328745977
Pubmed

Interaction network of human early embryonic transcription factors.

RANBP2 HDAC5 RGPD1 PRR12 ATXN1 TET1 PAXIP1 TAF1 QSER1 SLX4

7.55e-063511651038297188
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RANBP2 RGPD8 RGPD1

8.63e-069165318394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RANBP2 RGPD8 RGPD1

8.63e-069165328100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RANBP2 RGPD8 RGPD1

8.63e-069165317887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RANBP2 RGPD8 RGPD1

8.63e-069165311553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RANBP2 RGPD8 RGPD1

8.63e-069165310601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RANBP2 RGPD8 RGPD1

8.63e-06916539733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RANBP2 RGPD8 RGPD1

8.63e-069165328877029
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RANBP2 RGPD8 RGPD1

1.23e-0510165327160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RANBP2 RGPD8 RGPD1

1.23e-0510165316332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RANBP2 RGPD8 RGPD1

1.23e-051016538857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RANBP2 RGPD8 RGPD1

1.23e-0510165321859863
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

FRAS1 VTN COL6A5 VCAN NID1

1.38e-0564165522261194
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RANBP2 RGPD8 RGPD1

1.68e-0511165317069463
Pubmed

Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.

FAT4 TJP1 MIP

1.68e-0511165326114487
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RANBP2 RGPD8 RGPD1

1.68e-0511165335771867
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RANBP2 RGPD8 RGPD1

1.68e-0511165334110283
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNB SDK2 RGPD8 GON4L MAST2 OGDH EFTUD2 DHX15

1.73e-05234165836243803
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

PDE4D ITGA2 ADRB2 PTPRZ1 VCAN CDH13 TBCE

1.86e-05171165720201926
Pubmed

Differential association of phosphodiesterase 4D isoforms with beta2-adrenoceptor in cardiac myocytes.

PDE4D ADRB2

2.24e-052165219801680
Pubmed

N-ethylmaleimide-sensitive factor regulates beta2 adrenoceptor trafficking and signaling in cardiomyocytes.

NSF ADRB2

2.24e-052165217510209
Pubmed

Vitronectin, a Novel Urinary Proteomic Biomarker, Promotes Cell Pyroptosis in Juvenile Systemic Lupus Erythematosus.

VTN NLRP3

2.24e-052165235462789
Pubmed

A major functional role for phosphodiesterase 4D5 in human airway smooth muscle cells.

PDE4D ADRB2

2.24e-052165217673687
Pubmed

Siglec-6 Signaling Uses Src Kinase Tyrosine Phosphorylation and SHP-2 Recruitment.

PTPN11 SIGLEC6

2.24e-052165236359823
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

2.24e-052165223544943
Pubmed

Epithelial differentiation and intercellular junction formation in the mouse early embryo.

TJP1 CGN

2.24e-05216521299356
Pubmed

ADAR3 alleviated inflammation and pyroptosis of neuropathic pain by targeting NLRP3 in chronic constriction injury mice.

ADARB2 NLRP3

2.24e-052165234419568
Pubmed

RNA m6A reader YTHDF1 facilitates inflammation via enhancing NLRP3 translation.

NLRP3 YTHDF1

2.24e-052165235649302
Pubmed

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

CPS1 JMJD1C NLRP3 FGA

2.28e-0535165423969696
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RANBP2 RGPD8 RGPD1

2.90e-0513165331427429
Pubmed

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

THSD4 ATP6V1B1 GBP6 VTN PLOD3 MUC16 VTA1 BMP3 FUT2 MUC4

3.31e-054171651019199708
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

FAT4 FRAS1 PLOD3 RGPD8 EFTUD2 DHX15 PRR12 STARD9 NID1 TNFRSF19 DSE

3.70e-055131651125798074
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ZHX3 JMJD1C MED24 PRR12 ATXN1 PAXIP1 TAF1 QSER1

4.53e-05268165833640491
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RANBP2 RGPD8 RGPD1

4.58e-0515165314697343
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

UNC13B DMGDH CPAMD8 EXO5 GALNS INHBC ALS2 ITGA2 CPS1 SLC22A18 ATXN1 VCAN CGN LRP6 TAF1 BCAM HYDIN INVS

4.61e-0512931651815342556
Pubmed

The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation.

TJP1 NID1 SMAD4

5.61e-0516165319733164
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

GBP6 ZNF366 GON4L VTA1 IQCN MTMR10 ITGB6 ANKRD27 SULF1 ARNT2 RAB39B RNF180 RGPD5

6.50e-057501651311230166
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

6.69e-053165223053434
Pubmed

β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation.

PDE4D ADRB2

6.69e-053165220705779
Pubmed

Potential role of entactin in hemostasis. Specific interaction of entactin with fibrinogen A alpha and B beta chains.

FGA NID1

6.69e-05316521680863
Pubmed

Identification of new interacting partners of the shuttling protein ubinuclein (Ubn-1).

TJP1 CGN

6.69e-053165222245583
Pubmed

Sex-specific association of rs16996148 SNP in the NCAN/CILP2/PBX4 and serum lipid levels in the Mulao and Han populations.

PBX4 CILP2

6.69e-053165222208664
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

6.69e-053165230236127
Pubmed

HDAC5 RNA interference ameliorates acute renal injury by upregulating KLF2 and inhibiting NALP3 expression in a mouse model of oxalate nephropathy.

HDAC5 NLRP3

6.69e-053165236183679
Pubmed

The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.

SIRT6 TET1

6.69e-053165225915124
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

6.69e-053165227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

6.69e-053165224204560
Pubmed

Human and Xenopus cingulin share a modular organization of the coiled-coil rod domain: predictions for intra- and intermolecular assembly.

TJP1 CGN

6.69e-053165211042084
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

6.69e-053165224939955
Pubmed

Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4.

PDE4D ADRB2

6.69e-053165218188154
Pubmed

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes.

ADRB2 SMAD4

6.69e-05316529506519
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

6.69e-053165217592322
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

6.69e-053165235879412
Pubmed

Evidence for a functional interaction between cingulin and ZO-1 in cultured cells.

TJP1 CGN

6.69e-053165212023291
Pubmed

Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.

UNC13B NSF

6.69e-053165221812969
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RANBP2 ZBTB2 RGPD8 RGPD1 TET1 QSER1

7.30e-05146165623892456
Pubmed

Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.

IL16 NCKAP5 ADRB2 CDH13

7.43e-0547165418821565
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

FLNB RANBP2 PLOD3 RGPD8 NSF RGPD1 IDH3A OGDH JMJD1C EFTUD2 DHX15 ATXN1

8.57e-056651651230457570
Pubmed

An integrated genetic map of the pearl locus of mouse chromosome 13.

PDE4D ITGA2 VCAN

9.61e-051916538828042
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

FLNB RANBP2 RPN2 RADX SHKBP1 EFTUD2 DHX15 CILP2 CGN KCTD3

1.01e-044771651031300519
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

VTN VCAN NID1 BCAM CDH13

1.02e-0497165527559042
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

RANBP2 RGPD8 RGPD1 ITGA2 IDH3A EFTUD2 TJP1

1.09e-04226165737839992
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

PLOD3 LRCH2 RGPD1 EFTUD2 DHX15 MED24 GTF2F2 FGA TAF1

1.10e-04390165917643375
Pubmed

Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.

RANBP2 RGPD8 RGPD1 JMJD1C MUC4

1.13e-0499165527746211
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

GON4L ALS2 ZSWIM6 WDFY4 NCOA5

1.24e-04101165510997877
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RANBP2 ANK1 RGPD8 SPEG RGPD1 PTPRZ1 FGA

1.24e-04231165716452087
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZBTB2 WDFY4 JMJD1C SCAF4 EFTUD2 NCOA5 PRR12 N4BP2 CGN SLX4

1.32e-044931651015368895
Pubmed

Crosstalk Between RPE Cells and Choroidal Endothelial Cells via the ANXA1/FPR2/SHP2/NLRP3 Inflammasome/Pyroptosis Axis Promotes Choroidal Neovascularization.

NLRP3 PTPN11

1.33e-044165234595678
Pubmed

Integrin alphavbeta6 mediates HT29-D4 cell adhesion to MMP-processed fibrinogen in the presence of Mn2+.

ITGB6 FGA

1.33e-044165217275949
GeneFamilyWD repeat domain containing

WSB2 WDFY4 EML3 WDR53 SHKBP1 WDR47 WDR97 WDR90

3.06e-042621178362
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RANBP2 RGPD8 RGPD1 CFAP70 RGPD5

9.07e-041151175769
CoexpressionLAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET

THSD4 RANBP2 MACC1 FRAS1 PDE4D ZSWIM6 ITGA2 JMJD1C ATXN1 TJP1 NFAT5

3.40e-0724016311M39236
CoexpressionNABA_CORE_MATRISOME

THSD4 FRAS1 VTN COL6A5 MEPE CILP2 OTOGL VCAN FGA NID1

7.87e-0627016310MM17057
CoexpressionWANG_SMARCE1_TARGETS_UP

FRAS1 PCDHB10 ITGA2 ATXN1 SULF1 VCAN NID1 ATP11C TNFRSF19 BCAM

1.65e-0529416310M1804
CoexpressionKOYAMA_SEMA3B_TARGETS_DN

GALNS GON4L ALS2 NLRP3 PTPN11 CGN PAXIP1 ATP11C QSER1 NFAT5 TBCE

1.86e-0536416311M2029
CoexpressionNABA_ECM_GLYCOPROTEINS

THSD4 FRAS1 VTN MEPE CILP2 OTOGL FGA NID1

2.72e-051911638MM17059
CoexpressionGSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN

ZHX3 NLRP3 ADRB2 TET1 CCDC15 ATP11C DSE

3.40e-051441637M335
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP

INHBC ITGB6 MEPE NRARP LPAR6 PI4KB FUT2 SLX4

3.52e-051981638M9829
CoexpressionGSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP

CERK GBP6 PBX4 ALS2 EML3 ATXN1 DSE INVS

3.65e-051991638M5687
CoexpressionHE_LIM_SUN_FETAL_LUNG_C6_MUC16_POS_CILIATED_CELL

GBP6 MUC16 ITGA2 VCAN MUC4

4.25e-05621635M45790
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN

ESS2 LRCH2 VCAN RAB39B

5.78e-05341634M11023
CoexpressionNABA_CORE_MATRISOME

THSD4 FRAS1 VTN COL6A5 MEPE CILP2 VCAN FGA NID1

5.92e-052751639M5884
CoexpressionNABA_MATRISOME

THSD4 FRAS1 IL16 VTN PLOD3 INHBC MUC16 COL6A5 MEPE BMP3 CILP2 SERPINB13 OTOGL SULF1 VCAN FGA NID1 MUC4

5.95e-05100816318MM17056
CoexpressionYAGUE_PRETUMOR_DRUG_RESISTANCE_DN

VCAN TNS1 DSE

6.45e-05131633M2070
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN

ESS2 LRCH2 VCAN RAB39B

7.27e-05361634MM486
CoexpressionNABA_MATRISOME

THSD4 CPAMD8 FRAS1 IL16 VTN PLOD3 INHBC MUC16 COL6A5 MEPE BMP3 CILP2 SERPINB13 SULF1 VCAN FGA NID1 MUC4

7.45e-05102616318M5889
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

PCSK2 CELF5 FAT4 PDE4D ANK1 ZSWIM6 MAST2 SEZ6L2 ADARB2 WDR47 ATP11C BICRAL CDH13

7.82e-0558416313M39068
CoexpressionHEBERT_MATRISOME_TNBC_LIVER_METASTASIS

VTN COL6A5 FGA

8.17e-05141633M48002
CoexpressionLINDGREN_BLADDER_CANCER_CLUSTER_3_DN

THSD4 PDE4D ZSWIM6 ITGA2 ATXN1 LPAR6 PI4KB SLC24A1

8.92e-052261638M11238
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PCDHB10 ITGA2 SEZ6L2 NRARP PRDM10 SULF1 BCAM CDH13

1.53e-08170165950c6c571591aa4b218caefe5778c570c809f567e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PCDHB10 ITGA2 SEZ6L2 NRARP PRDM10 SULF1 BCAM CDH13

1.53e-0817016598fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PCDHB10 ITGA2 SEZ6L2 NRARP PRDM10 SULF1 BCAM CDH13

1.53e-0817016593232db50b1a40f861e981a1b9c9073b81af9f832
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 NCKAP5 ITGA2 SERPINB13 PTPRZ1 BCAM MUC4 TNS1 CDH13

5.97e-08199165994a7867e800df352731796de8c24cba133c29622
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

FRAS1 ITGA2 ADARB2 SERPINB13 PTPRZ1 SULF1 BCAM MUC4

2.55e-0717116583965ced4be6db14265a90673502fceee425837ca
ToppCellcellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GBP6 MUC16 ITGA2 NRARP SERPINB13 PTPRZ1 FUT2 MUC4

7.76e-0719816586e047de63ef59dcb47e4fc06b173b2a02fdcf4c9
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZSWIM6 JMJD1C NLRP3 CILP2 VCAN SLX4 DSE

1.08e-0614316577adc34d8ad11e57950a5a258ae9bf8f52259385a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK2 EXO5 EML3 MMADHC SULF1 TET1 MFSD13A

2.29e-061601657778faada072e3abfa76a9a06fd4885fb63de7902
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ATP6V1B1 MUC16 ADARB2 NRARP SERPINB13 PTPRZ1 FUT2

2.48e-061621657112fa4de685727f6c8bf6fc4afb82de0524070ad
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ITGA2 ADARB2 SERPINB13 PTPRZ1 SULF1 BCAM MUC4

4.46e-061771657cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ITGA2 ADARB2 SERPINB13 PTPRZ1 SULF1 BCAM MUC4

4.46e-061771657ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRCH2 NCKAP5 ADARB2 TJP1 STARD9 NID1 TNS1

4.63e-061781657185b44700f06ec58b3c09c80520502166c965fd6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK2 FAT4 SDK2 OVOS2 NCKAP5 SEZ6L2 ADARB2

4.80e-061791657c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 FRAS1 ITGA2 ITGB6 CGN BCAM CDH13

4.80e-06179165704ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 PCDHGB2 SEZ6L2 ADARB2 PTPRZ1 ARNT2 CNTN2

5.16e-0618116573aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 PCDHGB2 SEZ6L2 ADARB2 PTPRZ1 ARNT2 CNTN2

5.16e-061811657997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 PCDHGB2 SEZ6L2 ADARB2 PTPRZ1 ARNT2 CNTN2

5.16e-061811657e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

UNC13B THSD4 FLNB PDE4D NCKAP5 ITGA2 ITGB6

5.55e-061831657dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 ANK1 CPS1 OTOGL HYDIN CNTN2

5.75e-0618416572cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 ANK1 CPS1 OTOGL HYDIN CNTN2

5.75e-061841657ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 ANK1 CPS1 OTOGL HYDIN CNTN2

5.75e-0618416572b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK2 FAT4 SDK2 OVOS2 NCKAP5 SEZ6L2 ADARB2

5.96e-06185165716e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCellTuft|World / Class top

FLNB IL16 ANK1 SEZ6L2 MYDGF CDH13 IL17RB

6.17e-061861657f4d83f15ab7b49c0920a322cd832413ece7c9948
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 FRAS1 SDK2 ITGA2 ITGB6 CGN BCAM

6.40e-06187165758d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellTuft-tuft-2|World / Class top

FLNB IL16 ANK1 SEZ6L2 MYDGF CDH13 IL17RB

6.40e-0618716574ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

PDE4D ITGA2 ADARB2 SERPINB13 PTPRZ1 BCAM MUC4

6.40e-0618716578407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell15-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

FRAS1 ITGA2 ITGB6 BMP3 ADRB2 PTPRZ1 BCAM

6.86e-061891657f128c2fc37f232d193de18a922c47fdd70e1982d
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 PDE4D VCAN LRP6 TNFRSF19 NFAT5 IL17RB

7.60e-061921657916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MACC1 FRAS1 PDE4D UGT3A1 MTMR10 BCAM

7.60e-0619216579e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MACC1 FRAS1 PDE4D UGT3A1 MTMR10 BCAM

7.60e-0619216573d777d07878269b87ec7e1f06489cae7c989d633
ToppCell367C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

VTN MOSPD2 ZNF366 OVOS2 ARNT2 ATP11C RNF180

7.60e-061921657e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THSD4 PDE4D RGPD8 ZSWIM6 JMJD1C ATXN1 NFAT5

7.86e-061931657779276e775cb2492e8dd36436295a536084a6415
ToppCellBronchial_Brush-Epithelial-Basal_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

THSD4 FRAS1 NCKAP5 PTPRZ1 TET1 BCAM CDH13

8.98e-061971657f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

MUC16 ITGA2 NRARP SERPINB13 PTPRZ1 FUT2 MUC4

8.98e-061971657b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 VTN PCDHGB2 SLC30A1 SEZ6L2 SULF1 CPXM1

8.98e-06197165726888af95a7cc082a1f1218af35b1f07cb9436ed
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 VTN PCDHGB2 SLC30A1 SEZ6L2 SULF1 CPXM1

8.98e-061971657438de7f0d35d81d5f5e41dcef7b2c54b6da03df4
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FAT4 IL16 SDK2 PDE4D ITGA2 VCAN TNFRSF19

8.98e-061971657f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

UNC13B NCKAP5 ITGB6 ADRB2 CGN BCAM TNS1

9.28e-06198165775bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell21-Trachea-Epithelial-Club-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

ATP6V1B1 MACC1 MUC16 BMP3 VCAN FUT2 MUC4

9.28e-061981657e735d82e5151c98b5724c543f8ad633c8ed824d2
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA2 ITGB6 SERPINB13 PTPRZ1 BCAM MUC4 CDH13

9.28e-0619816575374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

UNC13B FRAS1 NCKAP5 KIDINS220 TJP1 BCAM CDH13

9.59e-06199165711c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ITGA2 NRARP SERPINB13 PTPRZ1 SULF1 BCAM TNS1

9.59e-0619916572add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 FLNB FAT4 ANK1 SULF1 BCAM CDH13

9.59e-0619916576a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ITGA2 ADARB2 NRARP SERPINB13 PTPRZ1 MUC4

9.59e-061991657f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D ITGA2 MTMR10 ITGB6 TNFRSF19 BCAM NFAT5

9.59e-0619916573cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12|Neuronal / cells hierarchy compared to all cells using T-Statistic

SDK2 OVOS2 NCKAP5 ADARB2 PTPRZ1 NID1 ATP11C

9.91e-062001657c74bc12e13d002dedaaf75a2244ec111e47524e1
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MACC1 MUC16 ITGA2 TJP1 CGN FUT2 MUC4

9.91e-062001657d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

SDK2 OVOS2 NCKAP5 ADARB2 PTPRZ1 NID1 ATP11C

9.91e-062001657ead9eb579bb25fde05fc15602e3d05ab6617f7ac
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TNFAIP8L3-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

SDK2 RADX OVOS2 ADARB2 BMP3 PTPRZ1 ATP11C

9.91e-062001657978dfb3c1d5e1c3d778a089175c50b8b719626c0
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FAT4 FRAS1 SDK2 COL6A5 ITGA2 NID1 CDH13

9.91e-062001657aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FAT4 FRAS1 SDK2 COL6A5 ITGA2 NID1 CDH13

9.91e-062001657a510deaada669e690329183e18df02870bd204b3
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ITGA2 SERPINB13 PTPRZ1 BCAM MUC4 CDH13

9.91e-0620016579da214f756a03516eaafde00289b90f69623b9f3
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CPAMD8 FAT4 IL16 STARD9 VCAN NID1 TNS1

9.91e-062001657c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TNFAIP8L3|Neuronal / cells hierarchy compared to all cells using T-Statistic

SDK2 RADX OVOS2 ADARB2 BMP3 PTPRZ1 ATP11C

9.91e-062001657d28b27776c46054b01bdd1e0f1db7c5cd5a48b88
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 ITGA2 NRARP SERPINB13 PTPRZ1 FUT2 MUC4

9.91e-062001657ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 ITGA2 TJP1 PTPRZ1 CGN BCAM MUC4

9.91e-062001657ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAT4 FRAS1 SDK2 COL6A5 ITGA2 NID1 CDH13

9.91e-062001657dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MACC1 COL6A5 ITGA2 CFAP70 SLC24A1

1.91e-05881655fcc15c5c30517c63a835b28627c5f779d9bcd17e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MACC1 COL6A5 ITGA2 CFAP70 SLC24A1

1.91e-058816557838c65160cf81c02b923fc34f566c0610c8d81b
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRCH2 PCDHGB2 EFTUD2 VCAN WDR90 CNTN2

1.98e-051491656651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellDendritic_Cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

FLNB IL16 ZNF366 RGPD1 SLX4 DSE

2.13e-051511656e089bf197ed60e7243160521d4390d4b40a3832b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT4 CPS1 ADARB2 PTPRZ1 VCAN ATP11C

2.21e-0515216568ff5a178a8f3550d89a003c0858820aab3773386
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POM121L2 COL6A5 FAM135B NID1 MUC4 HYDIN

2.47e-0515516568fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL6A5 CPS1 PTPRZ1 SULF1 HYDIN

2.95e-051601656c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL6A5 CPS1 PTPRZ1 SULF1 HYDIN

2.95e-05160165625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellMonocytes-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

PRDM10 FAM106A LPAR6 VCAN

3.25e-05491654bf67f5dee042fd680c661db637fde715e48b14c5
ToppCell368C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

FLNB ITGA2 WDFY4 EML3 SLX4 IL17RB

3.28e-051631656299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SDK2 RGPD8 ZC3H10 VCAN TNS1 TBCE

3.63e-051661656f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 SDK2 ITGA2 SERPINB13 PTPRZ1 CNTN2

3.63e-051661656aea2ae12e4746149ebc6da063ef694381c098f80
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH MOGAT1 UGT3A1 SLC22A18 TMEM174 FGA

3.88e-051681656b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 LRCH2 SPEG SULF1 IZUMO1 CDH13

4.01e-051691656c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ZHX3 SDK2 RGPD8 ZNF366 WDFY4 DSE

4.28e-05171165604346d4eb726875e3537e215ea081a0318ca4ddd
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL16 ZBTB2 WDR53 N4BP2 CD40LG TBCE

4.28e-051711656f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PBX4 NLRP3 SLC22A18 CILP2 CD40LG DSE

4.28e-051711656bdd30100b74e012eec3090799c22635aa57fa91d
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B NCKAP5 CILP2 OTOGL N4BP2 IZUMO1

4.43e-051721656f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B NCKAP5 CILP2 OTOGL N4BP2 IZUMO1

4.43e-0517216566ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellLeuk-UTI-Myeloid-cDC1|Leuk-UTI / Disease, Lineage and Cell Type

ZNF366 NCKAP5 IDH3A WDFY4 NRARP DSE

4.57e-051731656226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MACC1 MUC16 SERPINB13 PTPRZ1 FUT2 MUC4

4.72e-0517416569e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZHX3 FAT4 LRCH2 NID1 TNS1 DSE

4.87e-0517516561799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

DMGDH VTN INHBC UGT3A1 FGA FOLH1B

4.87e-0517516567f74961436f88c0e380819095e6104489914d765
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

DMGDH VTN INHBC UGT3A1 FGA FOLH1B

4.87e-051751656bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PBX4 FAM135B PTPRZ1 VCAN CPXM1 DSE

4.87e-051751656d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PBX4 FAM135B PTPRZ1 VCAN CPXM1 DSE

4.87e-0517516561d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Neuronal|GW13 / Sample Type, Dataset, Time_group, and Cell type.

SEZ6L2 KIDINS220 PTPRZ1

5.27e-05201653383fa9245ad41596b085fe4c33dc8e910f43538a
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 FRAS1 MUC16 CILP2 SULF1 CPXM1

5.36e-051781656bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 FRAS1 MUC16 CILP2 SULF1 CPXM1

5.36e-051781656c413861148129be1ee94f2ceb5999840217eebe5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MTMR10 BCAM NFAT5 HYDIN SLX4

5.36e-051781656c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

UNC13B THSD4 MACC1 NCKAP5 ITGB6 CGN

5.52e-051791656a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SDK2 POM121L2 BMP3 CPXM1 NID1 TNS1

5.52e-051791656b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

THSD4 SPEG SULF1 VCAN TNS1 CDH13

5.70e-051801656d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 MACC1 FRAS1 PDE4D TET1 FGA

5.70e-051801656023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 SDK2 ANK1 OVOS2 NCKAP5 ADARB2

5.70e-051801656b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRCH2 ADARB2 OTOGL STARD9 NID1 TNS1

5.88e-051811656451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MACC1 MTMR10 ITGB6 NFAT5 HYDIN

5.88e-0518116566a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 OVOS2 NCKAP5 SEZ6L2 ADARB2 ATP11C

5.88e-0518116562f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 ANK1 OVOS2 ADARB2 PTPRZ1 CDH13

6.06e-051821656d3a037268f026eb2f84428b1821022503cef7756
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB NRARP TJP1 SULF1 TNS1 CDH13

6.06e-051821656c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB NRARP TJP1 SULF1 TNS1 CDH13

6.06e-051821656d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell367C-Myeloid-Dendritic-cDC1|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF366 NCKAP5 WDFY4 NLRP3 NRARP DSE

6.06e-0518216566f5228ac47f9ab46d165740cf2655b5ba217acbe
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

FRAS1 SDK2 ITGA2 PM20D2 PTPRZ1 SULF1

6.24e-05183165600a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
Diseasebilirubin measurement

ZHX3 FAT4 ANK1 PBX4 CPS1 JMJD1C NLRP3 SHKBP1 SLC22A18 CILP2 PTPN11 MIP MYDGF FUT2

9.15e-0844215414EFO_0004570
Diseasealkaline phosphatase measurement

ZHX3 MACC1 INHBC ZNF366 PBX4 CPS1 SLC30A1 JMJD1C NLRP3 MED24 CILP2 PTPN11 ZNF45 IZUMO1 BCAM FUT2 NFAT5 MFSD13A

6.33e-06101515418EFO_0004533
Diseaseglycosyl-N-(2-hydroxynervonoyl)-sphingosine (d18:1/24:1(2OH)) measurement

RGPD1 CPS1 PRDM10

7.66e-0681543EFO_0800533
Diseasefibrinogen measurement

PCSK2 CPS1 JMJD1C NLRP3 PRR12 FGA

2.38e-051091546EFO_0004623
Diseasecorneal resistance factor

ZHX3 ITGA2 MTMR10 ATXN1 TJP1 VCAN TET1 ARNT2 LRP6 CPXM1 TNS1

2.67e-0545115411EFO_0010067
Diseaseresponse to hydrochlorothiazide, fasting blood glucose measurement

MOGAT1 VTA1 ADARB2 OTOGL

9.82e-05461544EFO_0004465, EFO_0005202
Diseaseneutrophil count, basophil count

ZNF366 VTA1 MAST2 JMJD1C NLRP3 ADRB2 ATXN1

1.83e-042241547EFO_0004833, EFO_0005090
Diseasegranulocyte count

ZNF366 MAST2 JMJD1C NLRP3 MED24 ADRB2 ATXN1

3.91e-042541547EFO_0007987
Diseaseblood nickel measurement

PDE4D MUC16 VTA1 NLRP3 TNS1

4.27e-041201545EFO_0007583
Diseaselung carcinoma, family history of lung cancer

PCSK2 ADARB2 PM20D2

4.61e-04291543EFO_0001071, EFO_0006953
DiseaseBleeding tendency

PTPN11 SMAD4

5.59e-0471542C1458140
Diseasepentachlorophenol measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022071
Diseaseparathion measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022070
Diseasepotassium chromate measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022072
Diseasemercuric chloride measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022068
Diseaseheptachlor epoxide measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022067
Diseasemethoxychlor measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022069
Disease4,6-dinitro-o-cresol measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022053
Disease2,4,5-trichlorophenol measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022052
Diseaseazinphos methyl measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022055
Diseasealdrin measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022054
Diseasedicofol measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022060
Diseasedisulfoton measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022062
Diseasedieldrin measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022061
Diseaseendrin measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022064
Diseaseendosulfan measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022063
Diseaseheptachlor measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022066
Diseaseethion measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022065
Diseasechlorpyrifos measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022057
Diseasecadmium chloride measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022056
Diseasediazinon measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022059
Diseasedibutyl phthalate measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0022058
Diseaseenvironmental exposure measurement

PDE4D MUC16 NLRP3 TNS1

5.87e-04731544EFO_0008360
DiseaseDDT metabolite measurement

PDE4D MUC16 NLRP3 TNS1

6.18e-04741544EFO_0007886
Diseaseinternet addiction disorder

FLNB ANK1 NID1

6.78e-04331543EFO_0803368
DiseaseDisproportionate short stature

FLNB PTPN11 SULF1 TBCE

7.18e-04771544C0878659
Diseaseurticaria (is_implicated_in)

NLRP3 ADRB2

7.42e-0481542DOID:1555 (is_implicated_in)
Diseasebreast cancer anti-estrogen resistance protein 3 measurement

VTN JMJD1C

7.42e-0481542EFO_0008040
Diseaseperiodontal disease (biomarker_via_orthology)

IL16 CD40LG

7.42e-0481542DOID:3388 (biomarker_via_orthology)
Diseaseretinal detachment, retinal break

CPAMD8 FRAS1 BMP3

8.07e-04351543EFO_0005773, EFO_0010698
Diseaseascending aortic diameter

THSD4 FLNB JMJD1C HYDIN CDH13

8.59e-041401545EFO_0021787
Diseaseurate measurement

ATP6V1B1 HDAC5 INHBC GON4L CPS1 JMJD1C ITGB6 MEPE TMEM174 PTPN11 NID1 NFAT5 CNTN2

8.67e-0489515413EFO_0004531
Diseasecervical cancer (is_marker_for)

MACC1 PTPN11 SMAD4

8.77e-04361543DOID:4362 (is_marker_for)
Diseaseneutrophil count

CELF5 FLNB CPAMD8 MOSPD2 ZNF366 VTA1 CPS1 MAST2 JMJD1C NLRP3 MED24 KIDINS220 ADRB2 ATXN1 CGN MFSD13A HYDIN

9.22e-04138215417EFO_0004833
Diseasesystemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus

FLNB PRR12 PTPN11

1.03e-03381543EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

DMGDH VTN JMJD1C PTPN11 BCAM NFAT5

1.13e-032221546EFO_0008317, EFO_0020943
Diseasecholelithiasis

CPS1 JMJD1C FUT2 NFAT5

1.18e-03881544EFO_0004799
Diseasesmoking status measurement, chronic obstructive pulmonary disease

THSD4 POM121L2 MED24 TNS1

1.18e-03881544EFO_0000341, EFO_0006527
Diseasephospholipids:total lipids ratio

DMGDH VTN INHBC JMJD1C NCOA5 BCAM

1.27e-032271546EFO_0020946
Diseasesleep duration, low density lipoprotein cholesterol measurement

ZHX3 PBX4 OGDH BCAM

1.34e-03911544EFO_0004611, EFO_0005271
Diseaseglutamine measurement, amino acid measurement

CPS1 MIP

1.44e-03111542EFO_0005134, EFO_0009768
Diseasegastrin-releasing peptide measurement

VTN JMJD1C

1.44e-03111542EFO_0022000
DiseaseCrohn's disease of large bowel

VTN NLRP3 FUT2

1.58e-03441543C0156147
DiseaseIIeocolitis

VTN NLRP3 FUT2

1.58e-03441543C0949272
DiseaseCrohn's disease of the ileum

VTN NLRP3 FUT2

1.58e-03441543C0267380
DiseaseRegional enteritis

VTN NLRP3 FUT2

1.58e-03441543C0678202
Diseasefibrinogen measurement, tissue plasminogen activator measurement

CPS1 JMJD1C NLRP3

1.68e-03451543EFO_0004623, EFO_0004791
Diseasefibrinogen measurement, plasminogen activator inhibitor 1 measurement

CPS1 JMJD1C NLRP3

1.68e-03451543EFO_0004623, EFO_0004792
Diseaseendometrial carcinoma (is_implicated_in)

CDH13 SMAD4

1.73e-03121542DOID:2871 (is_implicated_in)
Diseaseblood cobalt measurement

PDE4D MUC16 NLRP3 TNS1

1.97e-031011544EFO_0007577
Diseasesodium measurement

MAST2 JMJD1C ADRB2 NFAT5

2.11e-031031544EFO_0009282
Diseaseresponse to fenofibrate

JMJD1C FAM135B CDH13

2.28e-03501543GO_1901557
DiseaseCrohn Disease

VTN NLRP3 FUT2

2.28e-03501543C0010346
Diseasegallstones

CPS1 JMJD1C FUT2 NFAT5

2.51e-031081544EFO_0004210
Diseaseblood urea nitrogen measurement

GON4L CPS1 TMEM174 MIP IZUMO1 WDR90 FUT2 NFAT5

2.66e-034521548EFO_0004741
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

PLOD3 VCAN SMAD4

2.70e-03531543C4707243
Diseasecancer biomarker measurement

FAM135B FUT2

2.72e-03151542EFO_0005127
Diseasethrombosis (is_implicated_in)

VTN ITGA2

2.72e-03151542DOID:0060903 (is_implicated_in)
Diseasesusceptibility to common cold measurement

IL16 ANKRD27 FUT2

2.85e-03541543EFO_0008417
Diseaseforced expiratory volume

THSD4 DMGDH ANK1 POM121L2 VTA1 JMJD1C EML3 ADRB2 SULF1 NFAT5 TNS1

2.96e-0378915411EFO_0004314
Diseaseserum non-albumin protein measurement

ZNF366 UGT3A1 CPS1 MAST2 NLRP3 PTPN11 FUT2

2.96e-033611547EFO_0004568
DiseaseIschemic stroke, fibrinogen measurement

CPS1 JMJD1C NLRP3

3.00e-03551543EFO_0004623, HP_0002140
DiseaseDiGeorge Syndrome

ESS2 JMJD1C

3.10e-03161542C0012236
DiseaseCONOTRUNCAL ANOMALY FACE SYNDROME

ESS2 JMJD1C

3.10e-03161542C0795907
Diseaseureidopropionic acid measurement

CPS1 ADARB2

3.10e-03161542EFO_0010542
DiseaseBlood Coagulation Disorders

PTPN11 SMAD4

3.10e-03161542C0005779
DiseaseIdiopathic pulmonary arterial hypertension

HDAC5 SMAD4

3.10e-03161542C3203102
DiseaseShprintzen syndrome

ESS2 JMJD1C

3.10e-03161542C0220704
DiseaseDrug habituation

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C0013170
DiseaseDrug abuse

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C0013146
DiseasePrescription Drug Abuse

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C4316881
DiseaseSubstance-Related Disorders

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C0236969
DiseaseDrug Use Disorders

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C0013222
DiseaseDrug Dependence

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C1510472
DiseaseSubstance Dependence

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C0038580
DiseaseSubstance Use Disorders

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

THSD4 ZNF366 ADARB2 CDH13

3.15e-031151544C0029231
Diseaseovarian cancer (is_implicated_in)

MUC16 CDH13 SMAD4

3.16e-03561543DOID:2394 (is_implicated_in)
DiseaseSubstance abuse problem

THSD4 ZNF366 ADARB2 CDH13

3.25e-031161544C0740858
Diseasetriglycerides to total lipids in small VLDL percentage

DMGDH JMJD1C BCAM

3.49e-03581543EFO_0022338
Diseasefibrinogen measurement, factor VII measurement

CPS1 JMJD1C NLRP3

3.49e-03581543EFO_0004619, EFO_0004623
Diseaseerythritol measurement

MAST2 ITGB6

3.50e-03171542EFO_0021171
Diseasesphingomyelin 14:0 measurement

PDE4D NID1

3.50e-03171542EFO_0010390
DiseaseFamilial primary pulmonary hypertension

HDAC5 SMAD4

3.50e-03171542C0340543
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TJP1 CD40LG

3.50e-03171542DOID:8677 (biomarker_via_orthology)
Diseasetriglycerides to total lipids in small LDL percentage

DMGDH JMJD1C BCAM

3.66e-03591543EFO_0022337
DiseaseAlzheimer disease, polygenic risk score

FRAS1 PCDHGB2 ZNF366 ZSWIM6 MAST2 ZNF45 BCAM NFAT5 HYDIN

3.77e-035861549EFO_0030082, MONDO_0004975
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

DMGDH CPS1 JMJD1C BCAM

3.78e-031211544EFO_0008595, EFO_0020943
Diseasemonocyte count

FLNB ZBTB2 ANK1 INHBC ZNF366 GON4L PBX4 IQCN MAST2 OGDH MED24 CILP2 ATXN1 VCAN MYDGF

3.91e-03132015415EFO_0005091
Diseaseacute pancreatitis

RADX ADRB2

3.92e-03181542EFO_1000652

Protein segments in the cluster

PeptideGeneStartEntry
VSSLQGHRNFPTGTV

BMP3

256

P12645
DFVGHQGTVPSDNID

ADRB2

386

P07550
TTEHSSIHQPGVQEG

VCAN

1806

P13611
SVFVNVTDPSQVSHG

CD40LG

236

P29965
NTFGQLGHSDFPTTV

ALS2

586

Q96Q42
GSANAESVQGVTPLH

ANK1

626

P16157
ETGNHDSFPGAVVSI

FAM106A

111

Q4KMX7
GPLNGASEVTFSVHV

FAT4

2526

Q6V0I7
VDAGHPTRFSGVITQ

CPXM1

176

Q96SM3
SHSPGVAVIQFAVGE

ATXN1

621

P54253
TIINGNPGQSFEIHT

CDH13

401

P55290
VNGTFIIHPDSGNLT

CDHR5

296

Q9HBB8
VRHQSFVLVGETGSG

DHX15

151

O43143
AFSSSVVHVPGVNDI

ARNT2

536

Q9HBZ2
HVNPAVTFAFLVGSQ

MIP

66

P30301
QGSQTFHGAPLTVAT

RANBP2

856

P49792
SGFVPNVVHSSEEVV

RAB39B

191

Q96DA2
AVVGPSHEVQEQSSG

QSER1

961

Q2KHR3
SQTGPVHAPVFAVAV

ADARB2

146

Q9NS39
QGSQTFHGAPLTVAT

RGPD5

856

Q99666
QGSQTFHGAPLTVAT

RGPD8

856

O14715
VAAGTPNTSGSIHEN

IQCN

536

Q9H0B3
TNESGVFITGHRGQP

RADX

461

Q6NSI4
GVNVTSQDGSSPLHV

ANKRD27

736

Q96NW4
GPSVLRHAQQGGFSV

EXO5

251

Q9H790
RIIQAHGGTVDPTFT

PAXIP1

631

Q6ZW49
SGGFIGFATTIHQIV

PLOD3

166

O60568
GTHVVVGSIFTNATP

MMADHC

271

Q9H3L0
THGASLVPVVSFGEN

MOGAT1

216

Q96PD6
IGESTAGPTTHQFAV

MUC16

591

Q8WXI7
FHTQQSEGAETTGRP

MUC4

451

Q99102
ETGNHDSFPGAVVSI

FAM106C

111

P0CH98
QIFGARHLSPTETDG

KIDINS220

421

Q9ULH0
HTPVVAGTSRGFQAQ

FRAS1

3301

Q86XX4
VFISHSNVGIGTIVG

SLC24A1

516

O60721
IQTGFAGPSEAESTH

MEPE

281

Q9NQ76
SFGPEGQTALHQSVI

NRARP

46

Q7Z6K4
PEAQISLGGSITAFH

MTMR10

666

Q9NXD2
AQSSVILGGAAHRPF

INHBC

206

P55103
GSETGANHISPFLSQ

JMJD1C

721

Q15652
IQHSTIIGFSQVFEP

IL17RB

211

Q9NRM6
FTVDSRPLTQVGGDH

FLNB

1251

O75369
VVDNGDGTHTVTYTP

FLNB

1471

O75369
VGDTASFSVTVNIPH

ITGB6

411

P18564
TNHGAAGVPFASDTI

PCDHGB2

791

Q9Y5G2
SPGSGLILQANFVHS

PDE4D

171

Q08499
FTRQAEVTFVGHPGN

NID1

516

P14543
SRGGSPFAIVITQQH

NCOA5

246

Q9HCD5
QSGAAVVHETVRSFG

FOLH1B

81

Q9HBA9
VHRVFPNGLASQEGT

IL16

1141

Q14005
GSGSQFVVTAQIAHP

LRP6

391

O75581
GPSIDVQSFTVHGDS

DSE

666

Q9UL01
FSTTIHVPNIATGEQ

NSF

661

P46459
QNHGFPLGSTVQSET

GBP6

61

Q6ZN66
GGSAPAVFVQSTHSQ

LPAR6

146

P43657
AAQVHFVPDTGTVAQ

PRDM10

21

Q9NQV6
QSHPGDFVLSVRTGD

PTPN11

141

Q06124
SAIPVHDSVGVTYQG

PTPRZ1

946

P23471
TFHVAVIVTEFGTGN

OVOS2

296

Q6IE36
TISPNSFFHINISGG

PCDHB10

171

Q9UN67
TGESTHFVAGAPRAN

ITGA2

446

P17301
VVTNAGRSHDVQPFT

NFAT5

526

O94916
HIGNVASSVPVENFT

OGDH

616

Q02218
ASSVPVENFTIHGGL

OGDH

621

Q02218
TAVDTTEVGVPGNHA

PBX4

286

Q9BYU1
IDFCPGQNVSGVTTH

GALNS

416

P34059
ATFETPEVHAGTGVV

ESS2

106

Q96DF8
FGHPSSVAGEVVFNT

CPS1

61

P31327
NGVAIFESVHGTAPD

IDH3A

281

P50213
HVFGSGTQLTVLSQP

IGLL1

96

P15814
VPANGEVTLQVHFSS

HYDIN

2746

Q4G0P3
FSPIDSTVDVGQSVH

HYDIN

4256

Q4G0P3
IGVTHVPVGASFASN

BICRAL

166

Q6AI39
HLVSGQTFAASGSPV

BICRAL

471

Q6AI39
EGTVSFLPAQHTVGS

CERK

326

Q8TCT0
EIHTLQETVGFGNPS

CFAP70

1106

Q5T0N1
QVNGSRPGTFVGVHV

FUT2

186

Q10981
VVGFDISTHVQGQPL

COL6A5

1196

A8TX70
EGPLFHNQTSVTVDG

CPAMD8

111

Q8IZJ3
TVAETLHPAFSGVQQ

CELF5

351

Q8N6W0
PSHGRVAGFEVQSLQ

GON4L

51

Q3T8J9
VVRGSGHVTVFGLSN

CHIC2

31

Q9UKJ5
FIPTDGRHFVSQTTG

CNTN2

176

Q02246
HPDGTIQVSNGSLAF

CAPRIN2

826

Q6IMN6
VPQGHVAVGEFQEVS

MACC1

236

Q6ZN28
LQTHPSGTQSGIFNI

FGA

636

P02671
EETGQVVGFHQPGSI

DMGDH

121

Q9UI17
VVGFHQPGSIRLATT

DMGDH

126

Q9UI17
RVTPDAVHSVGGNSS

MAST2

1281

Q6P0Q8
GSVNSSPATIINFHV

IZUMO1

236

Q8IYV9
FHPSGAVVAVGLNTG

EML3

646

Q32P44
VHGVLNGVAPSSATN

SDR39U1

211

Q9NRG7
ITHQPLGSFGVVSTH

FAM135B

1066

Q49AJ0
HSTIAENGFTGSVPN

HDAC5

326

Q9UQL6
HFGTVSPQTSQAGVA

BCAM

536

P50895
VAQNGGAETSHTEPV

SCAF4

641

O95104
RPNFQDSIHVGFVSG

SDK2

846

Q58EX2
TVGSGPQLFQTFTVH

KCTD3

406

Q9Y597
GHDLFQQSLITPVGS

MFSD13A

431

Q14CX5
VPEQGNAHIGSFVSF

LRCH2

416

Q5VUJ6
GQHGVPIDFRTQISF

OTOGL

726

Q3ZCN5
QGSQTFHGAPLTVAT

RGPD1

841

P0DJD0
SVAPHETQTQRGGEF

RNF180

296

Q86T96
GRTPLHFAVADGNVT

INVS

221

Q9Y283
SEPVHTVVFQGAAGI

NLRP3

216

Q96P20
VSPHGGLTVSAQDRF

MOSPD2

391

Q8NHP6
HPFVLQSVGGQTLTV

GTF2F2

81

P13984
VHFTLPDGTQRSGQV

ATP6V1B1

66

P15313
GEPIEFSSHQTGVVT

NCKAP5

676

O14513
RGTFGGNIIQHSIPA

TAF1

581

P21675
GAFSQVTLHATAQAP

PKDREJ

656

Q9NTG1
FEGQPSLSTEGHSIQ

SMAD4

166

Q13485
ILGSRTAGPHTQFVQ

MED24

911

O75448
GIAPVGFSQHETVDS

RHBDF1

426

Q96CC6
THVGFPENLTNGATA

POTEJ

511

P0CG39
VGSGPQLFQTFTVHR

SHKBP1

416

Q8TBC3
QFQTGIVSDHPAEAG

SIGLEC6

401

O43699
RTASDAGFPVGSHVQ

SEZ6L2

716

Q6UXD5
SPTRHGFLGAGVVSQ

STARD9

4536

Q9P2P6
HTFPQLQVEQSGEGS

PRR12

1911

Q9ULL5
QARGVHQSVATDGPS

NDUFS7

26

O75251
GITHEQRAGSFSTVP

PI4KB

436

Q9UBF8
VSQNVDGLHVRSGFP

SIRT6

111

Q8N6T7
RIVIQTHQSGAFGSV

POM121L2

866

Q96KW2
STDFGNVSFVVPGIH

PM20D2

351

Q8IYS1
FGVPVFGHVQVAINT

SLC22A18

391

Q96BI1
PSRAGVHAQQEATTG

SLX4

1636

Q8IY92
TTSFLGQAFGAIPHQ

TET1

361

Q8NFU7
VPGGNSTLRVAIHNF

CCDC15

926

Q0P6D6
HGVQIRFITEPVSGA

CGN

16

Q9P2M7
TVATSDAHGTFRVPG

CILP2

236

Q8IUL8
TFAVQVHSPVPSEAG

CNK3/IPCEF1

701

G9CGD6
GTRTVFVGNHPVSET

ATP11C

21

Q8NB49
GVGTRHVQEFISGQS

RNF149

186

Q8NC42
FHGTGSAVASVAVDP

WDR47

796

O94967
PSIRLFVTHGGQNSV

UGT3A1

361

Q6NUS8
QQVTLTTHAPFGLGA

TMEM223

131

A0PJW6
TGTTFRVLSDHQGAP

WDR90

1556

Q96KV7
VVEGQPASVTVTFNH

SPEG

1401

Q15772
VNGEHATVRFAGVVP

TBCE

16

Q15813
VFGNHSPLERVSGVV

RNF148

61

Q8N7C7
VDVNTGAELTPHQTF

RPN2

421

P04844
IGFTVTSAPGHENVH

SERPINB13

351

Q9UIV8
AEVPHSTGVASNTIQ

VTA1

226

Q9NP79
GALGQHFSQSPRVTV

WDR97

936

A6NE52
QARAQFSVAGVHTVP

TNS1

1161

Q9HBL0
AVGQLGVRVFHSSPA

WDFY4

1351

Q6ZS81
GEVSIQVDLFTHPGT

UNC13B

1421

O14795
TPLGHTRFQGADDVT

WDR53

41

Q7Z5U6
NGQAVHGELSPVTDF

U2AF1L4

136

Q8WU68
HQGLSAVATASPGVF

nan

111

Q6ZVQ6
GRDNPHFQSGETSIV

TJP1

41

Q07157
VFTGINQPITFHGAT

TMEM174

121

Q8WUU8
GFHLSGTVTEPAIQS

ZSWIM6

226

Q9HCJ5
GPAAAFAGTVTIHNQ

ZXDA

156

P98168
VPVFQSDGESAQGSH

ZNF366

601

Q8N895
VGGAVPVQSHSENFT

TNFRSF19

356

Q9NS68
HTGVPFTSSQQGESR

ZBTB2

276

Q8N680
GHQDVVRDLSFTPSG

WSB2

151

Q9NYS7
APTVGTVATFNHGIA

ZC3H10

296

Q96K80
GIHATTIQPEFASVG

SLC30A1

411

Q9Y6M5
VGTHGATQSFSQPAR

THSD4

271

Q6ZMP0
PGHVNFSDEVTAGLR

EFTUD2

206

Q15029
REGDHSFINGAVPVS

ZHX3

226

Q9H4I2
EHGGATFINAFVTTP

SULF1

71

Q8IWU6
NATVHEQVGGPSLTS

VTN

86

P04004
FRNVVSVGHQSTPDG

ZNF45

41

Q02386
VFQEGAGTHFPSVRV

nan

186

Q6ZTC4
TVVDGQPGFHSDTLS

YTHDF1

161

Q9BYJ9
SNFVQVTHQGGPVFV

GARIN5B

46

Q8N5Q1
TTVAFDVRPGGVVHS

MYDGF

36

Q969H8
DVRPGGVVHSFSHNV

MYDGF

41

Q969H8
VPEFSHGIGISNADS

N4BP2

1176

Q86UW6
TVPERFHCVGGSVQD

PCSK2

461

P16519