Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled photoreceptor activity	OPN1MW2 OPN1MW3 OPN1MW	4.78e-06	15	45	3	GO:0008020
GeneOntologyMolecularFunction	photoreceptor activity	OPN1MW2 OPN1MW3 OPN1MW	7.11e-06	17	45	3	GO:0009881
GeneOntologyBiologicalProcess	detection of visible light	OPN1MW2 OPN1MW3 IRX6 OPN1MW	7.18e-06	57	45	4	GO:0009584
GeneOntologyBiologicalProcess	detection of light stimulus	OPN1MW2 OPN1MW3 IRX6 OPN1MW	2.38e-05	77	45	4	GO:0009583
GeneOntologyCellularComponent	photoreceptor disc membrane	OPN1MW2 OPN1MW3 OPN1MW	2.34e-05	26	45	3	GO:0097381
HumanPheno	Abnormal left hemidiaphragm morphology	WT1 GATA6	5.99e-05	5	13	2	HP:0040046
HumanPheno	Aplasia of the left hemidiaphragm	WT1 GATA6	5.99e-05	5	13	2	HP:0040048
HumanPheno	Aplasia of the left hemidiaphragm	WT1 GATA6	5.99e-05	5	13	2	HP:0009112
HumanPheno	Abnormal hemidiaphragm morphology	WT1 GATA6	1.25e-04	7	13	2	HP:0040045
HumanPheno	Denervation of the diaphragm	WT1 GATA6	1.25e-04	7	13	2	HP:0009109
HumanPheno	Bicuspid aortic valve	WT1 GATA6 NOTCH3 SCAF4	1.72e-04	119	13	4	HP:0001647
HumanPheno	Abnormal aortic valve cusp morphology	WT1 GATA6 NOTCH3 SCAF4	1.83e-04	121	13	4	HP:0031567
HumanPheno	Aplasia/Hypoplasia of the diaphragm	WT1 GATA6	2.14e-04	9	13	2	HP:0010315
Domain	Opsin_red/grn	OPN1MW3 OPN1MW	1.48e-05	3	42	2	IPR000378
Domain	OPSIN	OPN1MW3 OPN1MW	2.20e-04	10	42	2	PS00238
Domain	Opsin	OPN1MW3 OPN1MW	2.68e-04	11	42	2	IPR001760
Domain	Integrin_alpha	ITGAD ITGAX	2.68e-04	11	42	2	PF00357
Domain	Integrin_alpha_C_CS	ITGAD ITGAX	5.81e-04	16	42	2	IPR018184
Domain	Integrin_alpha-2	ITGAD ITGAX	7.38e-04	18	42	2	IPR013649
Domain	Integrin_alpha2	ITGAD ITGAX	7.38e-04	18	42	2	PF08441
Domain	Integrin_alpha	ITGAD ITGAX	7.38e-04	18	42	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGAD ITGAX	7.38e-04	18	42	2	PS00242
Domain	Int_alpha_beta-p	ITGAD ITGAX	8.24e-04	19	42	2	IPR013519
Domain	Int_alpha	ITGAD ITGAX	8.24e-04	19	42	2	SM00191
Domain	FG_GAP	ITGAD ITGAX	1.11e-03	22	42	2	PS51470
Domain	FG-GAP	ITGAD ITGAX	1.32e-03	24	42	2	PF01839
Domain	FG-GAP	ITGAD ITGAX	1.32e-03	24	42	2	IPR013517
Domain	Integrin_dom	ITGAD ITGAX	1.43e-03	25	42	2	IPR032695
Domain	Homeodomain-like	HOXA13 IRX6 KDM1B NKX2-4	6.45e-03	332	42	4	IPR009057
Domain	VWA	ITGAD ITGAX	7.04e-03	56	42	2	PF00092
Domain	Homeobox_CS	HOXA13 IRX6 NKX2-4	8.39e-03	186	42	3	IPR017970
Domain	RRM_1	CPEB2 RBFOX2 SCAF4	1.14e-02	208	42	3	PF00076
Domain	RRM	CPEB2 RBFOX2 SCAF4	1.27e-02	217	42	3	SM00360
Pathway	REACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION	OPN1MW2 OPN1MW3	1.14e-04	8	29	2	MM14880
Pathway	REACTOME_OPSINS	OPN1MW2 OPN1MW3	1.82e-04	10	29	2	MM15063
Pubmed	Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.	OPN1MW2 OPN1MW3 OPN1MW	8.09e-09	4	45	3	29386880
Pubmed	Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.	OPN1MW2 OPN1MW3 OPN1MW	2.02e-08	5	45	3	2937147
Pubmed	Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.	OPN1MW2 OPN1MW3 IRX6 BSN	2.91e-07	43	45	4	25228773
Pubmed	Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors.	OPN1MW2 OPN1MW	1.64e-06	2	45	2	28402104
Pubmed	Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb.	ITGAD ITGAX	1.64e-06	2	45	2	9598326
Pubmed	Defective colour vision associated with a missense mutation in the human green visual pigment gene.	OPN1MW2 OPN1MW	1.64e-06	2	45	2	1302020
Pubmed	Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype.	OPN1MW2 OPN1MW	1.64e-06	2	45	2	10319869
Pubmed	Molecular determinants of human red/green color discrimination.	OPN1MW2 OPN1MW	4.91e-06	3	45	2	8185948
Pubmed	X-linked cone dystrophy caused by mutation of the red and green cone opsins.	OPN1MW2 OPN1MW	4.91e-06	3	45	2	20579627
Pubmed	Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	38410159
Pubmed	Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	23350963
Pubmed	Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	20471354
Pubmed	Multiple hypothalamic cell populations encoding distinct visual information.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	21224225
Pubmed	Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	28751656
Pubmed	Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	36216501
Pubmed	Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	31469404
Pubmed	The molecular genetics and evolution of red and green color vision in vertebrates.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	11545071
Pubmed	Mechanisms of spectral tuning in the mouse green cone pigment.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	9238068
Pubmed	Emergence of novel color vision in mice engineered to express a human cone photopigment.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	17379811
Pubmed	Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	10567724
Pubmed	Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	34111401
Pubmed	Co-expression of murine opsins facilitates identifying the site of cone adaptation.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	12511072
Pubmed	The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	7958444
Pubmed	Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.	OPN1MW2 OPN1MW3	4.91e-06	3	45	2	14500905
Pubmed	Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina.	OPN1MW2 OPN1MW3 NOTCH3	5.15e-06	26	45	3	19828801
Pubmed	Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1.	OPN1MW2 OPN1MW3 ATN1	8.87e-06	31	45	3	16702404
Pubmed	Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	26438865
Pubmed	Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	17249565
Pubmed	Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	38060327
Pubmed	Contribution of M-opsin-based color vision to refractive development in mice.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	34126082
Pubmed	Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	16567464
Pubmed	Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	31461375
Pubmed	S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	24801621
Pubmed	Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	8088841
Pubmed	Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	28103478
Pubmed	Melanopsin Contributions to the Representation of Images in the Early Visual System.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	28528909
Pubmed	Molecular biology of the visual pigments.	OPN1MW2 OPN1MW	9.81e-06	4	45	2	3303660
Pubmed	Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	31846668
Pubmed	Melanopsin-driven light adaptation in mouse vision.	OPN1MW2 OPN1MW3	9.81e-06	4	45	2	25308073
Pubmed	A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages.	WT1 GATA6	1.63e-05	5	45	2	31231034
Pubmed	Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	36631163
Pubmed	Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	26818794
Pubmed	A common integration locus in type B retrovirus-induced thymic lymphomas.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	1333116
Pubmed	Melanopsin-based brightness discrimination in mice and humans.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	22633808
Pubmed	Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes.	ITGAD ITGAX	1.63e-05	5	45	2	15210787
Pubmed	The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	11055434
Pubmed	A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	22090509
Pubmed	Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	10723722
Pubmed	Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	24058409
Pubmed	CD11a regulates hematopoietic stem and progenitor cells.	ITGAD ITGAX	1.63e-05	5	45	2	37781399
Pubmed	Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	34099749
Pubmed	Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.	OPN1MW2 OPN1MW3	1.63e-05	5	45	2	27033727
Pubmed	CD11c regulates hematopoietic stem and progenitor cells under stress.	ITGAD ITGAX	1.63e-05	5	45	2	33351105
Pubmed	Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.	OPN1MW2 OPN1MW3	2.45e-05	6	45	2	23288843
Pubmed	Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.	OPN1MW2 OPN1MW3	2.45e-05	6	45	2	8872469
Pubmed	A thyroid hormone receptor that is required for the development of green cone photoreceptors.	OPN1MW2 OPN1MW3	2.45e-05	6	45	2	11138006
Pubmed	GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina.	OPN1MW2 OPN1MW	2.45e-05	6	45	2	12853434
Pubmed	Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase.	OPN1MW2 OPN1MW3	2.45e-05	6	45	2	10395695
Pubmed	Unique functions of Gata4 in mouse liver induction and heart development.	WT1 GATA6	2.45e-05	6	45	2	26687508
Pubmed	Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis.	OPN1MW2 OPN1MW3	2.45e-05	6	45	2	17436273
Pubmed	Telomere-related markers for the pseudoautosomal region of the mouse genome.	OPN1MW2 OPN1MW3	2.45e-05	6	45	2	1549575
Pubmed	Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	8378320
Pubmed	Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	18974269
Pubmed	Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	30799247
Pubmed	Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	16574740
Pubmed	Rods progressively escape saturation to drive visual responses in daylight conditions.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	29180667
Pubmed	Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	8001979
Pubmed	NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	18199774
Pubmed	Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X Chromosomes.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	9880679
Pubmed	Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.	OPN1MW2 OPN1MW3	3.42e-05	7	45	2	19332056
Pubmed	X-chromosome gene order in different Mus species crosses.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	3416629
Pubmed	The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	12651948
Pubmed	Transcriptional profiling of murine retinas undergoing semi-synchronous cone photoreceptor differentiation.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	31163126
Pubmed	Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	20203194
Pubmed	Tubby is required for trafficking G protein-coupled receptors to neuronal cilia.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	23351594
Pubmed	Localization of the mdx mutation within the mouse dystrophin gene.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	2903046
Pubmed	Epicardial GATA factors regulate early coronary vascular plexus formation.	WT1 GATA6	4.56e-05	8	45	2	24380800
Pubmed	A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3).	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	10725384
Pubmed	Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	16043864
Pubmed	Hepatocyte nuclear factor 4 alpha is related to survival of the condensed mesenchyme in the developing mouse kidney.	WT1 GATA6	4.56e-05	8	45	2	20235219
Pubmed	Nr2e3 functional domain ablation by CRISPR-Cas9D10A identifies a new isoform and generates retinitis pigmentosa and enhanced S-cone syndrome models.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	33007388
Pubmed	Genetic mapping on the mouse X chromosome of human cDNA clones for the fragile X and Hunter syndromes.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	1572654
Pubmed	Linkage of amelogenin (Amel) to the distal portion of the mouse X chromosome.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	1675194
Pubmed	Two transcription factors can direct three photoreceptor outcomes from rod precursor cells in mouse retinal development.	OPN1MW2 OPN1MW3	4.56e-05	8	45	2	21813673
Pubmed	Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	14742273
Pubmed	A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	27669145
Pubmed	Close linkage of the murine locus bare patches to the X-linked visual pigment gene: implications for mapping human X-linked dominant chondrodysplasia punctata.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	1973136
Pubmed	Feedback induction of a photoreceptor-specific isoform of retinoid-related orphan nuclear receptor β by the rod transcription factor NRL.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	25296752
Pubmed	Comparative mapping of the actin-binding protein 280 genes in human and mouse.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	8088838
Pubmed	Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	12407160
Pubmed	ZBED4, a cone and Müller cell protein in human retina, has a different cellular expression in mouse.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	21850176
Pubmed	Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	28370415
Pubmed	IFT20 is required for opsin trafficking and photoreceptor outer segment development.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	21307337
Pubmed	Multilocus molecular mapping of the mouse X chromosome.	OPN1MW2 OPN1MW3	5.86e-05	9	45	2	2906327
Pubmed	Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye.	OPN1MW2 OPN1MW3	7.32e-05	10	45	2	21148184
Pubmed	Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.	OPN1MW2 OPN1MW3	7.32e-05	10	45	2	31949211
Pubmed	Comparative mapping on the mouse and human X chromosomes of a human cDNA clone encoding the vasopressin renal-type receptor (AVP2R).	OPN1MW2 OPN1MW3	7.32e-05	10	45	2	8449515
Pubmed	Mapping of ornithine aminotransferase gene sequences to mouse chromosomes 7, X, and 3.	OPN1MW2 OPN1MW3	7.32e-05	10	45	2	1349842
Pubmed	The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.	OPN1MW2 OPN1MW3	7.32e-05	10	45	2	32236127
Pubmed	Physical mapping of the loci Gabra3, DXPas8, CamL1, and Rsvp in a region of the mouse X chromosome homologous to human Xq28.	OPN1MW2 OPN1MW3	7.32e-05	10	45	2	1684949
Interaction	RERE interactions	ATN1 RBFOX2 PRRC2B ALG13	4.57e-05	93	43	4	int:RERE
Interaction	DMRTB1 interactions	CPEB2 RBFOX2 PRRC2B ALG13	4.76e-05	94	43	4	int:DMRTB1
Cytoband	Ensembl 112 genes in cytogenetic band chrXq28	OPN1MW2 OPN1MW3 OPN1MW	1.21e-03	213	45	3	chrXq28
GeneFamily	Opsin receptors	OPN1MW2 OPN1MW3 OPN1MW	4.86e-07	11	27	3	215
GeneFamily	CD molecules\|Integrin alpha subunits	ITGAD ITGAX	3.24e-04	18	27	2	1160
GeneFamily	RNA binding motif containing	CPEB2 RBFOX2 SCAF4	3.83e-03	213	27	3	725
Coexpression	GSE17721_CTRL_VS_CPG_8H_BMDC_DN	GPR137B HOXA13 MAPKAPK2 DDHD1 NOTCH3	1.66e-05	200	42	5	M3768
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP3 DLEC1 BSN KCTD11	8.26e-06	130	44	4	1720f16ac06951c3f57b6c3b0944670a571203d1
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KIDINS220 KDM1B ITGAX MN1	1.31e-05	146	44	4	447c05414eda71681a0c07baba900f88ed6165ed
ToppCell	Leuk-UTI-Lymphocyte-T_NK-gdT\|Leuk-UTI / Disease, Lineage and Cell Type	TBC1D19 GATA6 ITGAD RBFOX2	1.78e-05	158	44	4	c4b0af25608cee3d0d2b0193f5ff45d9dc87078b
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CDK2AP2 ITGAX RAB44 DDHD1	1.87e-05	160	44	4	694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR137B ITGAD ITGAX PYGO1	2.06e-05	164	44	4	758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSM14B MN1 NOTCH3 RBFOX2	2.32e-05	169	44	4	2d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSM14B MN1 NOTCH3 RBFOX2	2.32e-05	169	44	4	ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSM14B MN1 NOTCH3 RBFOX2	2.32e-05	169	44	4	ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPN1MW ITGAX RAB44 DDHD1	2.84e-05	178	44	4	de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR137B ITGAX RAB44 DDHD1	3.30e-05	185	44	4	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	WT1 TMEM184C MN1 ALG13	3.59e-05	189	44	4	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WT1 GATA6 ENPP2 SULT1E1	3.74e-05	191	44	4	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WT1 GATA6 ENPP2 SULT1E1	3.74e-05	191	44	4	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	facs-GAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WT1 GATA6 ENPP2 SULT1E1	3.74e-05	191	44	4	1f5d1e8c313a8dc83c06d2ee45f369b0ec507fbf
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WT1 GATA6 ENPP2 SULT1E1	3.74e-05	191	44	4	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	WT1 TMEM184C MN1 ALG13	3.98e-05	194	44	4	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	KIDINS220 RBFOX2 PRRC2B CCSER2	4.48e-05	200	44	4	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Frontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Igsf8_(Ctps)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ITGAD NKX2-4 RAB44	6.55e-05	79	44	3	eddad041c0bc6952d9c68a36bdd78f6d661f0e58
ToppCell	Frontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Igsf8_(Ctps)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ITGAD NKX2-4 RAB44	6.55e-05	79	44	3	4c9c3051cb8a9c39c6df20e3fe37242db4b44280
Disease	blue cone monochromacy (implicated_via_orthology)	OPN1MW2 OPN1MW3 OPN1MW	1.15e-08	4	43	3	DOID:0050679 (implicated_via_orthology)
Disease	Feeding difficulties	ATN1 MN1	3.13e-04	18	43	2	C0232466
Disease	upper face morphology measurement	GPR137B DLEC1 ENPP2	3.86e-04	97	43	3	EFO_0010949
Disease	Congenital diaphragmatic hernia	WT1 GATA6	4.28e-04	21	43	2	C0235833
Disease	congenital heart disease (is_implicated_in)	GATA6 RBFOX2	5.61e-04	24	43	2	DOID:1682 (is_implicated_in)
Disease	Thyroid Gland Follicular Adenoma	ENPP2 PRDM2	1.20e-03	35	43	2	C0151468
Disease	sex interaction measurement, Crohn's disease	BSN MAPKAPK2	1.34e-03	37	43	2	EFO_0000384, EFO_0008343
Disease	Thyroid Neoplasm	ENPP2 PRDM2	1.34e-03	37	43	2	C0040136
Disease	Diaphragmatic Hernia	WT1 GATA6	1.64e-03	41	43	2	C0019284
Disease	Thyroid carcinoma	ENPP2 PRDM2	1.89e-03	44	43	2	C0549473
Disease	Acute Promyelocytic Leukemia	WT1 ITGAX	2.06e-03	46	43	2	C0023487

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPSPMGHYQGFGHTV	TMEM184C	391	Q9NVA4
NRHNMPGPKVDFYPG	ALG13	666	Q9NP73
RPHVMSPGNRNHPFY	ATN1	891	P54259
GSMYAPAQFQPGFIP	CECR2	741	Q9BXF3
QSGFLPHGVPSSGYM	CECR2	846	Q9BXF3
AAANPGYPFHPLMAA	OPN1MW3	291	P0DN78
MAGGGPQANPDYLFH	RAB44	821	Q7Z6P3
MQNEPLTPGYHGFPA	RBFOX2	1	O43251
SGGAFLYPPNMSPTF	ITGAX	376	P20702
MSFPHFGHPYRGASQ	IRX6	1	P78412
AAANPGYPFHPLMAA	OPN1MW2	291	P0DN77
FGPPMFVYTRPHPNS	OR4F21	251	O95013
SGMTGPQHPFYNRPF	KIDINS220	1126	Q9ULH0
ATYHMPPGVSQFPHG	NKX2-4	91	Q9H2Z4
PPGVSQFPHGAMGSY	NKX2-4	96	Q9H2Z4
PPFYSNHGLAISPGM	MAPKAPK2	261	P49137
SPFQPHVPYSPFRGM	LSM14B	106	Q9BX40
HAQRPEPMDGSGPYF	FER1L4	501	A9Z1Z3
AFRPTGHYAGQTPMP	BSN	3111	Q9UPA5
GQAMVFPYHRPSPGS	NOTCH3	1551	Q9UM47
AAANPGYPFHPLMAA	OPN1MW	291	P04001
GGAFLYPPNMSPTFI	ITGAD	376	Q13349
PLGHFESYGGMPFFQ	CCSER2	631	Q9H7U1
ARFPYSPSPPMANGA	GATA6	261	Q92908
PLFNDFGPPSMGYVQ	CDK2AP2	46	O75956
HVPGMNRYFQPFYQP	KDM1B	261	Q8NB78
GFYPGLPSSMNPAFF	CPEB2	11	Q7Z5Q1
SSTFPRMYPGQGPFD	DLGAP3	86	O95886
GLPMGTYQAFPNIHP	IST1	256	P53990
MNYPGRGSPRSPEHN	DDHD1	1	Q8NEL9
FFPHFSQGMLGPYQQ	DLEC1	1186	Q9Y238
GFPGDGMQQPAYTQH	SCAF4	321	O95104
HKYGPFGPEMTNPLR	ENPP2	316	Q13822
PPFQYHHRNPMGIGV	PRDM2	1301	Q13029
GGPMLPSQHAQFEYP	MN1	396	Q10571
FGPPMFVYTRPHPNS	OR4F3;	251	Q6IEY1
YVFNPNPGLFAVMHP	CFAP221	656	Q4G0U5
PMPPNLNSQGGGHYF	KCTD11	11	Q693B1
GMVPSHGFSPRSYFF	GPR137B	326	O60478
PGFGGYSTFRMPPHV	PYGO1	96	Q9Y3Y4
FPQNPLGMGFNRPHA	PYGO1	131	Q9Y3Y4
RFYEMFGHPQPGSAN	SHLD1	101	Q8IYI0
PSYFAHFHSGGMPAP	PRR32	276	B1ATL7
SGYYPCARMGPHPNA	HOXA13	176	P31271
FFLMVAGHPNPGSFP	SULT1E1	141	P49888
SSGQARMFPNAPYLP	WT1	121	P19544
PQRTFYPHHPQMLGF	PRRC2B	656	Q5JSZ5
NLAAPHGPGAFFRYM	ZIC4	106	Q8N9L1
NGVIPFHGFSMYVAP	TBC1D19	361	Q8N5T2