Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNA1D CACNA1E CACNA1F	1.23e-08	14	39	4	GO:0008331
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV	2.82e-08	46	39	5	GO:0005245
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	4.67e-07	152	39	6	GO:0022843
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1A CACNA1D CACNA1E	5.74e-07	9	39	3	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1A CACNA1D CACNA1E	5.74e-07	9	39	3	GO:0099626
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	1.34e-06	182	39	6	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	1.43e-06	184	39	6	GO:0022832
GeneOntologyMolecularFunction	calcium channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV	5.03e-06	129	39	5	GO:0005262
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV	1.08e-05	151	39	5	GO:0015085
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	2.86e-05	465	39	7	GO:0046873
GeneOntologyMolecularFunction	gated channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	4.29e-05	334	39	6	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	4.97e-05	343	39	6	GO:0005261
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	1.87e-04	627	39	7	GO:0022890
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	2.45e-04	459	39	6	GO:0005216
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	2.65e-04	664	39	7	GO:0008324
GeneOntologyMolecularFunction	channel activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	5.01e-04	525	39	6	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	5.06e-04	526	39	6	GO:0022803
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	5.88e-04	758	39	7	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	7.68e-04	793	39	7	GO:0015075
GeneOntologyMolecularFunction	dynein intermediate chain binding	SPTBN5 DNAH10	2.37e-03	37	39	2	GO:0045505
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	SMARCA2 SMARCA4	2.37e-03	37	39	2	GO:0140658
GeneOntologyMolecularFunction	integrin binding	ITGAV JAM3 FERMT3	4.80e-03	175	39	3	GO:0005178
GeneOntologyMolecularFunction	cell-cell adhesion mediator activity	IGSF9 JAM3	6.33e-03	61	39	2	GO:0098632
GeneOntologyMolecularFunction	ATP-dependent activity	SMARCA2 SMARCA4 CLPB DNAH10 KCNJ8	6.56e-03	614	39	5	GO:0140657
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	7.20e-03	1180	39	7	GO:0022857
GeneOntologyMolecularFunction	cell adhesion mediator activity	IGSF9 JAM3	9.67e-03	76	39	2	GO:0098631
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1A CACNA1D CACNA1E CACNA1F	1.80e-06	48	38	4	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1A CACNA1D CACNA1E CACNA1F	1.80e-06	48	38	4	GO:1902656
GeneOntologyBiologicalProcess	import across plasma membrane	SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	3.69e-06	230	38	6	GO:0098739
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	6.02e-06	142	38	5	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	6.02e-06	142	38	5	GO:0098659
GeneOntologyBiologicalProcess	calcium ion import	CACNA1A CACNA1D CACNA1E CACNA1F	3.12e-05	98	38	4	GO:0070509
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV	4.66e-05	217	38	5	GO:0097553
GeneOntologyBiologicalProcess	aortic smooth muscle cell differentiation	SMARCA2 SMARCA4	4.93e-05	6	38	2	GO:0035887
GeneOntologyBiologicalProcess	transmission of nerve impulse	CACNA1A CACNA1E KCNJ8 JAM3	5.27e-05	112	38	4	GO:0019226
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	7.48e-05	392	38	6	GO:0070588
GeneOntologyBiologicalProcess	calcium ion transport	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	3.09e-04	509	38	6	GO:0006816
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1A CACNA1D CACNA1E CACNA1F	1.60e-06	46	39	4	GO:0005891
GeneOntologyCellularComponent	calcium channel complex	CACNA1A CACNA1D CACNA1E CACNA1F	1.03e-05	73	39	4	GO:0034704
GeneOntologyCellularComponent	cation channel complex	CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	7.25e-05	235	39	5	GO:0034703
GeneOntologyCellularComponent	bBAF complex	SMARCA2 SMARCA4	1.51e-04	10	39	2	GO:0140092
GeneOntologyCellularComponent	npBAF complex	SMARCA2 SMARCA4	3.04e-04	14	39	2	GO:0071564
GeneOntologyCellularComponent	GBAF complex	SMARCA2 SMARCA4	3.04e-04	14	39	2	GO:0140288
GeneOntologyCellularComponent	transmembrane transporter complex	COX6C CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	3.85e-04	523	39	6	GO:1902495
GeneOntologyCellularComponent	nBAF complex	SMARCA2 SMARCA4	4.00e-04	16	39	2	GO:0071565
GeneOntologyCellularComponent	presynaptic active zone membrane	CACNA1A CACNA1D KCNJ8	4.15e-04	78	39	3	GO:0048787
GeneOntologyCellularComponent	transporter complex	COX6C CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	5.03e-04	550	39	6	GO:1990351
GeneOntologyCellularComponent	actin cytoskeleton	SPTBN5 WHRN CARMIL2 GAS2L2 JAM3 FERMT3	6.42e-04	576	39	6	GO:0015629
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	6.54e-04	378	39	5	GO:0034702
GeneOntologyCellularComponent	perikaryon	CACNA1A CACNA1D CACNA1E CACNA1F	7.74e-04	223	39	4	GO:0043204
GeneOntologyCellularComponent	SWI/SNF complex	SMARCA2 SMARCA4	1.43e-03	30	39	2	GO:0016514
GeneOntologyCellularComponent	presynaptic membrane	CACNA1A CACNA1D CACNA1E KCNJ8	1.72e-03	277	39	4	GO:0042734
GeneOntologyCellularComponent	photoreceptor cell cilium	SPTBN5 WHRN CACNA1F	2.21e-03	139	39	3	GO:0097733
GeneOntologyCellularComponent	presynaptic active zone	CACNA1A CACNA1D KCNJ8	2.30e-03	141	39	3	GO:0048786
GeneOntologyCellularComponent	actin filament	WHRN GAS2L2 JAM3	2.54e-03	146	39	3	GO:0005884
GeneOntologyCellularComponent	9+0 non-motile cilium	SPTBN5 WHRN CACNA1F	2.90e-03	153	39	3	GO:0097731
GeneOntologyCellularComponent	plasma membrane protein complex	CACNA1A CACNA1D CACNA1E CACNA1F ITGAV KCNJ8	3.11e-03	785	39	6	GO:0098797
GeneOntologyCellularComponent	photoreceptor connecting cilium	SPTBN5 WHRN	3.62e-03	48	39	2	GO:0032391
GeneOntologyCellularComponent	neuronal cell body	WHRN CACNA1A CACNA1D CACNA1E CACNA1F RIN1	4.22e-03	835	39	6	GO:0043025
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGAV JAM3	5.43e-03	59	39	2	GO:0098636
GeneOntologyCellularComponent	presynapse	WHRN CACNA1A CACNA1D CACNA1E KCNJ8 S1PR4	5.62e-03	886	39	6	GO:0098793
GeneOntologyCellularComponent	non-motile cilium	SPTBN5 WHRN CACNA1F	5.79e-03	196	39	3	GO:0097730
GeneOntologyCellularComponent	somatodendritic compartment	WHRN CACNA1A CACNA1D CACNA1E CACNA1F RIN1 IGSF9	6.98e-03	1228	39	7	GO:0036477
GeneOntologyCellularComponent	cell body	WHRN CACNA1A CACNA1D CACNA1E CACNA1F RIN1	7.05e-03	929	39	6	GO:0044297
Domain	GPHH_dom	CACNA1A CACNA1D CACNA1E CACNA1F	5.65e-10	7	39	4	IPR031649
Domain	VDCC_a1su_IQ	CACNA1A CACNA1D CACNA1E CACNA1F	5.65e-10	7	39	4	IPR014873
Domain	Ca_chan_IQ	CACNA1A CACNA1D CACNA1E CACNA1F	5.65e-10	7	39	4	SM01062
Domain	Ca_chan_IQ	CACNA1A CACNA1D CACNA1E CACNA1F	5.65e-10	7	39	4	PF08763
Domain	GPHH	CACNA1A CACNA1D CACNA1E CACNA1F	5.65e-10	7	39	4	PF16905
Domain	VDCCAlpha1	CACNA1A CACNA1D CACNA1E CACNA1F	3.38e-09	10	39	4	IPR002077
Domain	SnAC	SMARCA2 SMARCA4	4.25e-06	2	39	2	SM01314
Domain	QLQ	SMARCA2 SMARCA4	4.25e-06	2	39	2	PS51666
Domain	Gln-Leu-Gln_QLQ	SMARCA2 SMARCA4	4.25e-06	2	39	2	IPR014978
Domain	SnAC	SMARCA2 SMARCA4	4.25e-06	2	39	2	IPR029295
Domain	QLQ	SMARCA2 SMARCA4	4.25e-06	2	39	2	PF08880
Domain	SnAC	SMARCA2 SMARCA4	4.25e-06	2	39	2	PF14619
Domain	QLQ	SMARCA2 SMARCA4	4.25e-06	2	39	2	SM00951
Domain	Channel_four-helix_dom	CACNA1A CACNA1D CACNA1E CACNA1F	5.92e-06	57	39	4	IPR027359
Domain	-	CACNA1A CACNA1D CACNA1E CACNA1F	5.92e-06	57	39	4	1.20.120.350
Domain	CAC1F_C	CACNA1D CACNA1F	1.27e-05	3	39	2	PF16885
Domain	CAC1F_C	CACNA1D CACNA1F	1.27e-05	3	39	2	IPR031688
Domain	HSA	SMARCA2 SMARCA4	2.54e-05	4	39	2	SM00573
Domain	VDCC_L_a1su	CACNA1D CACNA1F	2.54e-05	4	39	2	IPR005446
Domain	HSA	SMARCA2 SMARCA4	2.54e-05	4	39	2	PS51204
Domain	HSA_dom	SMARCA2 SMARCA4	2.54e-05	4	39	2	IPR014012
Domain	HSA	SMARCA2 SMARCA4	2.54e-05	4	39	2	PF07529
Domain	BRK	SMARCA2 SMARCA4	6.34e-05	6	39	2	SM00592
Domain	BRK_domain	SMARCA2 SMARCA4	6.34e-05	6	39	2	IPR006576
Domain	BRK	SMARCA2 SMARCA4	6.34e-05	6	39	2	PF07533
Domain	Ion_trans_dom	CACNA1A CACNA1D CACNA1E CACNA1F	9.18e-05	114	39	4	IPR005821
Domain	Ion_trans	CACNA1A CACNA1D CACNA1E CACNA1F	9.18e-05	114	39	4	PF00520
Domain	Bromodomain_CS	SMARCA2 SMARCA4	1.34e-03	26	39	2	IPR018359
Domain	SNF2_N	SMARCA2 SMARCA4	2.03e-03	32	39	2	PF00176
Domain	SNF2_N	SMARCA2 SMARCA4	2.03e-03	32	39	2	IPR000330
Domain	BROMODOMAIN_1	SMARCA2 SMARCA4	2.70e-03	37	39	2	PS00633
Domain	Bromodomain	SMARCA2 SMARCA4	2.85e-03	38	39	2	PF00439
Domain	BROMODOMAIN_2	SMARCA2 SMARCA4	3.31e-03	41	39	2	PS50014
Domain	BROMO	SMARCA2 SMARCA4	3.47e-03	42	39	2	SM00297
Domain	Bromodomain	SMARCA2 SMARCA4	3.47e-03	42	39	2	IPR001487
Domain	-	SMARCA2 SMARCA4	3.47e-03	42	39	2	1.20.920.10
Domain	LRR_6	FBXL17 CARMIL2	5.88e-03	55	39	2	PF13516
Domain	Ig_I-set	IGSF9 JAM3 LRIT1	7.24e-03	190	39	3	IPR013098
Domain	I-set	IGSF9 JAM3 LRIT1	7.24e-03	190	39	3	PF07679
Domain	CH	SPTBN5 GAS2L2	8.13e-03	65	39	2	SM00033
Domain	CH	SPTBN5 GAS2L2	9.38e-03	70	39	2	PF00307
Domain	-	SPTBN5 GAS2L2	9.64e-03	71	39	2	1.10.418.10
Domain	Ank_2	DGKZ CLPB ANKRD33B	1.01e-02	215	39	3	PF12796
Domain	CH	SPTBN5 GAS2L2	1.02e-02	73	39	2	PS50021
Domain	CH-domain	SPTBN5 GAS2L2	1.07e-02	75	39	2	IPR001715
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1A CACNA1D CACNA1E CACNA1F	1.43e-07	23	30	4	M47666
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1A CACNA1D CACNA1E CACNA1F	2.04e-07	25	30	4	M47948
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1D CACNA1F	6.53e-05	6	30	2	M47762
Pathway	KEGG_TYPE_II_DIABETES_MELLITUS	CACNA1A CACNA1D CACNA1E	1.32e-04	47	30	3	M19708
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	CACNA1A CACNA1E	2.38e-04	11	30	2	M47958
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNA1A CACNA1E	2.38e-04	11	30	2	MM14498
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNA1A CACNA1E	2.38e-04	11	30	2	M26913
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	CACNA1A CACNA1D CACNA1E	2.88e-04	61	30	3	MM15071
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004	CACNA1D CACNA1F	3.92e-04	14	30	2	M47692
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	CACNA1A CACNA1D CACNA1E	4.70e-04	72	30	3	MM14631
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	CACNA1D CACNA1F ITGAV	5.09e-04	74	30	3	M39462
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	CACNA1D CACNA1F ITGAV	5.09e-04	74	30	3	M16376
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	CACNA1A CACNA1D CACNA1E CACNA1F	5.21e-04	178	30	4	M2890
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	CACNA1A CACNA1D CACNA1E	5.94e-04	78	30	3	M1921
Pathway	KEGG_CARDIAC_MUSCLE_CONTRACTION	COX6C CACNA1D CACNA1F	6.17e-04	79	30	3	M17673
Pathway	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	CACNA1D CACNA1F ITGAV	7.12e-04	83	30	3	M8728
Pathway	KEGG_DILATED_CARDIOMYOPATHY	CACNA1D CACNA1F ITGAV	9.02e-04	90	30	3	M835
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	CACNA1A CACNA1D CACNA1E	1.53e-03	108	30	3	M17034
Pathway	WP_KLEEFSTRA_SYNDROME	SMARCA2 SMARCA4	1.72e-03	29	30	2	M48076
Pathway	WP_MAPK_SIGNALING	CACNA1A CACNA1D CACNA1E CACNA1F	1.74e-03	246	30	4	M39597
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	CACNA1A CACNA1D CACNA1E CACNA1F	2.34e-03	267	30	4	M10792
Pathway	KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY	SMARCA2 SMARCA4	2.49e-03	35	30	2	M47969
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	SMARCA2 SMARCA4	2.78e-03	37	30	2	M27797
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1A CACNA1D CACNA1E CACNA1F	1.83e-09	15	39	4	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1A CACNA1D CACNA1E CACNA1F	1.83e-09	15	39	4	24453333
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1A CACNA1D CACNA1E	1.30e-08	5	39	3	11296258
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1A CACNA1D CACNA1E	1.30e-08	5	39	3	15451373
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1D CACNA1E CACNA1F	4.55e-08	7	39	3	12900400
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1D CACNA1E CACNA1F	7.27e-08	8	39	3	28330839
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1A CACNA1D CACNA1E CACNA1F	9.69e-08	38	39	4	30786075
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1A CACNA1E CACNA1F	1.09e-07	9	39	3	16382099
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	4.90e-07	139	39	5	16985003
Pubmed	Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.	SMARCA2 SMARCA4	1.23e-06	2	39	2	18508913
Pubmed	The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.	SMARCA2 SMARCA4	1.23e-06	2	39	2	8670841
Pubmed	Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.	SMARCA2 SMARCA4	1.23e-06	2	39	2	11719516
Pubmed	Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.	CACNA1D CACNA1E	1.23e-06	2	39	2	8071363
Pubmed	Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.	SMARCA2 SMARCA4	1.23e-06	2	39	2	23163725
Pubmed	The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.	SMARCA2 SMARCA4	1.23e-06	2	39	2	25808524
Pubmed	Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.	SMARCA2 SMARCA4	1.23e-06	2	39	2	19144648
Pubmed	Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.	SMARCA2 SMARCA4	1.23e-06	2	39	2	23076393
Pubmed	DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.	SMARCA2 SMARCA4	1.23e-06	2	39	2	28706277
Pubmed	Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.	CACNA1A CACNA1E	1.23e-06	2	39	2	16381801
Pubmed	Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.	SMARCA2 SMARCA4	1.23e-06	2	39	2	9603422
Pubmed	The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.	SMARCA2 SMARCA4	1.23e-06	2	39	2	15576411
Pubmed	[Expression of BRG1 and BRM proteins in prostatic cancer].	SMARCA2 SMARCA4	1.23e-06	2	39	2	21092585
Pubmed	High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.	SMARCA2 SMARCA4	1.23e-06	2	39	2	29391527
Pubmed	SWI/SNF gene variants and glioma risk and outcome.	SMARCA2 SMARCA4	1.23e-06	2	39	2	23276717
Pubmed	Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.	SMARCA2 SMARCA4	1.23e-06	2	39	2	27097303
Pubmed	Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.	SMARCA2 SMARCA4	1.23e-06	2	39	2	15240517
Pubmed	Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.	SMARCA2 SMARCA4	1.23e-06	2	39	2	26564006
Pubmed	Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.	SMARCA2 SMARCA4	1.23e-06	2	39	2	37634210
Pubmed	SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.	SMARCA2 SMARCA4	1.23e-06	2	39	2	26551623
Pubmed	SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.	SMARCA2 SMARCA4	1.23e-06	2	39	2	33027072
Pubmed	SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.	SMARCA2 SMARCA4	1.23e-06	2	39	2	28038711
Pubmed	A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.	SMARCA2 SMARCA4	1.23e-06	2	39	2	23872584
Pubmed	SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.	SMARCA2 SMARCA4	1.23e-06	2	39	2	19458193
Pubmed	Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.	SMARCA2 SMARCA4	1.23e-06	2	39	2	23963727
Pubmed	SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.	SMARCA2 SMARCA4	1.23e-06	2	39	2	12493776
Pubmed	Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.	SMARCA2 SMARCA4	1.23e-06	2	39	2	31375262
Pubmed	Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.	SMARCA2 SMARCA4	1.23e-06	2	39	2	23088494
Pubmed	C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.	CACNA1D CACNA1F	1.23e-06	2	39	2	16921373
Pubmed	Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.	SMARCA2 SMARCA4	1.23e-06	2	39	2	17075831
Pubmed	Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.	SMARCA2 SMARCA4	1.23e-06	2	39	2	8208605
Pubmed	The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.	SMARCA2 SMARCA4	1.23e-06	2	39	2	34289068
Pubmed	SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.	SMARCA2 SMARCA4	1.23e-06	2	39	2	34518526
Pubmed	SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.	SMARCA2 SMARCA4	1.23e-06	2	39	2	20333683
Pubmed	SMARCA family of genes.	SMARCA2 SMARCA4	1.23e-06	2	39	2	32312722
Pubmed	SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.	SMARCA2 SMARCA4	1.23e-06	2	39	2	34812766
Pubmed	Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.	SMARCA2 SMARCA4	1.23e-06	2	39	2	26356327
Pubmed	Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.	CACNA1D CACNA1F	1.23e-06	2	39	2	25966695
Pubmed	Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.	SMARCA2 SMARCA4	1.23e-06	2	39	2	32855269
Pubmed	Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.	SMARCA2 SMARCA4	1.23e-06	2	39	2	30478150
Pubmed	Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.	SMARCA2 SMARCA4	1.23e-06	2	39	2	12566296
Pubmed	A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.	SMARCA2 SMARCA4	1.23e-06	2	39	2	11163203
Pubmed	Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.	SMARCA2 SMARCA4	1.23e-06	2	39	2	12620226
Pubmed	SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.	SMARCA2 SMARCA4	1.23e-06	2	39	2	31406271
Pubmed	BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.	SMARCA2 SMARCA4	1.23e-06	2	39	2	27039070
Pubmed	Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.	SMARCA2 SMARCA4	1.23e-06	2	39	2	29848589
Pubmed	Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.	SMARCA2 SMARCA4	1.23e-06	2	39	2	29273066
Pubmed	Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.	SMARCA2 SMARCA4	1.23e-06	2	39	2	22721696
Pubmed	Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models.	SMARCA2 SMARCA4	3.67e-06	3	39	2	28292935
Pubmed	The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes.	SMARCA2 SMARCA4	3.67e-06	3	39	2	17938176
Pubmed	Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.	SMARCA2 SMARCA4	3.67e-06	3	39	2	36464671
Pubmed	The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.	CACNA1A CACNA1E	3.67e-06	3	39	2	38996073
Pubmed	Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart.	SMARCA2 SMARCA4	3.67e-06	3	39	2	22740088
Pubmed	BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2.	SMARCA2 SMARCA4	3.67e-06	3	39	2	15034933
Pubmed	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1.	SMARCA2 SMARCA4	3.67e-06	3	39	2	30287812
Pubmed	TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival.	SMARCA2 SMARCA4	3.67e-06	3	39	2	15075294
Pubmed	A putative nuclear receptor coactivator (TMF/ARA160) associates with hbrm/hSNF2 alpha and BRG-1/hSNF2 beta and localizes in the Golgi apparatus.	SMARCA2 SMARCA4	3.67e-06	3	39	2	12044884
Pubmed	SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development.	SMARCA2 SMARCA4	3.67e-06	3	39	2	21518954
Pubmed	Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.	CACNA1A CACNA1E	3.67e-06	3	39	2	24523520
Pubmed	Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma.	SMARCA2 SMARCA4	3.67e-06	3	39	2	19784067
Pubmed	Characterization of mammary tumors from Brg1 heterozygous mice.	SMARCA2 SMARCA4	3.67e-06	3	39	2	17637742
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1A CACNA1D	3.67e-06	3	39	2	23338940
Pubmed	BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.	SMARCA2 SMARCA4	3.67e-06	3	39	2	20571081
Pubmed	Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers.	SMARCA2 SMARCA4	3.67e-06	3	39	2	14603256
Pubmed	SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility†.	SMARCA2 SMARCA4	3.67e-06	3	39	2	36440965
Pubmed	Genetic dissection of horizontal cell inhibitory signaling in mice in complete darkness in vivo.	CACNA1D CACNA1F	3.67e-06	3	39	2	26024096
Pubmed	Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2.	SMARCA2 SMARCA4	3.67e-06	3	39	2	9099865
Pubmed	Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells.	CACNA1A CACNA1D	3.67e-06	3	39	2	32154672
Pubmed	Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.	CACNA1A CACNA1E	7.34e-06	4	39	2	32616470
Pubmed	BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes.	SMARCA2 SMARCA4	7.34e-06	4	39	2	23897427
Pubmed	Cerebellar granule cell signaling is indispensable for normal motor performance.	CACNA1A CACNA1E	7.34e-06	4	39	2	37141091
Pubmed	Dual role of NRSF/REST in activation and repression of the glucocorticoid response.	SMARCA2 SMARCA4	7.34e-06	4	39	2	17984088
Pubmed	Neuregulin-1 modulates the differentiation of neural stem cells in vitro through an interaction with the Swi/Snf complex.	SMARCA2 SMARCA4	7.34e-06	4	39	2	19781646
Pubmed	Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.	SMARCA2 SMARCA4	7.34e-06	4	39	2	31906887
Pubmed	Hypoxia-driven paracrine osteopontin/integrin αvβ3 signaling promotes pancreatic cancer cell epithelial-mesenchymal transition and cancer stem cell-like properties by modulating forkhead box protein M1.	FOXM1 ITGAV	7.34e-06	4	39	2	30367545
Pubmed	Brahma safeguards canalization of cardiac mesoderm differentiation.	SMARCA2 SMARCA4	7.34e-06	4	39	2	35082446
Pubmed	Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.	SMARCA2 SMARCA4	7.34e-06	4	39	2	19805516
Pubmed	SWI/SNF chromatin-remodeling enzymes Brahma-related gene 1 (BRG1) and Brahma (BRM) are dispensable in multiple models of postnatal angiogenesis but are required for vascular integrity in infant mice.	SMARCA2 SMARCA4	7.34e-06	4	39	2	25904594
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1D CACNA1F	7.34e-06	4	39	2	20937870
Pubmed	BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility.	SMARCA2 SMARCA4	7.34e-06	4	39	2	28232072
Pubmed	Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1-FoxM1 complex.	FOXM1 SMARCA4	7.34e-06	4	39	2	27601681
Pubmed	The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes.	SMARCA2 SMARCA4	7.34e-06	4	39	2	33481850
Pubmed	Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.	SMARCA2 SMARCA4	7.34e-06	4	39	2	9744861
Pubmed	BRM (SNF2alpha) expression is concomitant to the onset of vasculogenesis in early mouse postimplantation development.	SMARCA2 SMARCA4	7.34e-06	4	39	2	11231080
Pubmed	Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.	SMARCA2 SMARCA4	7.34e-06	4	39	2	24421395
Pubmed	Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.	SMARCA2 SMARCA4	7.34e-06	4	39	2	16452305
Pubmed	BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists.	SMARCA2 SMARCA4	7.34e-06	4	39	2	15141164
Pubmed	Control of B cell development by the histone H2A deubiquitinase MYSM1.	SMARCA2 SMARCA4	7.34e-06	4	39	2	22169041
Pubmed	Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cells.	SMARCA2 SMARCA4	1.22e-05	5	39	2	25801033
Pubmed	Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.	CACNA1A CACNA1E	1.22e-05	5	39	2	8825650
Pubmed	Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression.	SMARCA2 SMARCA4	1.22e-05	5	39	2	20011120
Cytoband	Ensembl 112 genes in cytogenetic band chr11q13	RIN1 PCNX3 CLPB FERMT3	5.90e-04	454	39	4	chr11q13
Cytoband	11q13.1	PCNX3 FERMT3	1.33e-03	63	39	2	11q13.1
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNA1D CACNA1E CACNA1F	7.79e-08	26	29	4	253
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Intermediate\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1A FBXL17 AFF2 GPATCH2L KCNJ8	8.20e-07	199	39	5	cf592d93612023a13de21e0fb8c6b13714f9af71
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	WHRN CACNA1E ZNF671 S1PR4	1.43e-05	169	39	4	c8691c4f707d46b2865fe46eabe24ea4d03c7b43
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXM1 CACNA1D AFF2 ANKRD33B	1.60e-05	174	39	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMARCA4 CACNA1E IGSF9 NOL9	1.91e-05	182	39	4	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMARCA4 CACNA1E IGSF9 NOL9	1.91e-05	182	39	4	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMARCA4 CACNA1E IGSF9 NOL9	1.91e-05	182	39	4	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-lymphocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN CACNA1E CARMIL2 S1PR4	1.95e-05	183	39	4	a305667cfdae50e64e1890f10f71b407ae617b80
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	FOXM1 B4GALNT3 AFF2 DNAH10	2.35e-05	192	39	4	0445fdc670fa7b847dcd0a061d7736ddcf3519ba
Drug	LY320135	FOXM1 CACNA1A CACNA1E S1PR4	6.36e-08	23	39	4	CID005311257
Drug	Barium	CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	1.45e-07	72	39	5	ctd:D001464
Drug	CNS 1145	CACNA1A CACNA1D CACNA1E CACNA1F	2.90e-07	33	39	4	CID000190902
Drug	IHC-64	CACNA1A CACNA1D CACNA1E CACNA1F	2.90e-07	33	39	4	CID000162753
Drug	Cinildipine	CACNA1A CACNA1D CACNA1E CACNA1F	2.53e-06	56	39	4	CID000002752
Drug	Verapamil	CACNA1A CACNA1D CACNA1F	2.56e-06	16	39	3	DB00661
Drug	nilvadipine	CACNA1A CACNA1D CACNA1E CACNA1F	3.34e-06	60	39	4	CID000004494
Drug	IAA-94	CACNA1A CACNA1D CACNA1E CACNA1F	3.57e-06	61	39	4	CID000003667
Drug	Isradipine	CACNA1D CACNA1E CACNA1F	3.72e-06	18	39	3	ctd:D017275
Drug	lercanidipine	CACNA1A CACNA1D CACNA1E CACNA1F	4.07e-06	63	39	4	CID000065866
Drug	AC1L1TJF	CACNA1A CACNA1D CACNA1E CACNA1F	4.91e-06	66	39	4	CID000003377
Drug	gallopamil	CACNA1A CACNA1D CACNA1E CACNA1F	5.21e-06	67	39	4	CID000001234
Drug	AC1L2AC7	CACNA1A CACNA1D CACNA1E CACNA1F	5.86e-06	69	39	4	CID000068733
Drug	CAS 298-57-7	CACNA1A CACNA1D CACNA1E CACNA1F	7.35e-06	73	39	4	CID000002761
Drug	ethosuximide	CACNA1A CACNA1D CACNA1E CACNA1F	7.76e-06	74	39	4	CID000003291
Drug	nisoldipine	CACNA1A CACNA1D CACNA1E CACNA1F	9.57e-06	78	39	4	CID000004499
Drug	N-cyclopentyl-N-cyclobutylformamide	CACNA1A CACNA1D CACNA1E CACNA1F	1.01e-05	79	39	4	CID005287890
Drug	lavendustin A	FOXM1 CACNA1A CACNA1D CACNA1E CACNA1F	1.06e-05	171	39	5	CID000003894
Drug	capsazepine	FOXM1 CACNA1A CACNA1D CACNA1E	1.28e-05	84	39	4	CID002733484
Drug	mAHP	CACNA1A CACNA1D CACNA1E	1.32e-05	27	39	3	CID000220531
Drug	NSC7524	CACNA1A CACNA1D CACNA1E CACNA1F S1PR4	1.43e-05	182	39	5	CID000005657
Drug	AC 110	CACNA1A CACNA1E	1.71e-05	4	39	2	CID000022860
Drug	baclofen	CACNA1A CACNA1D CACNA1E CACNA1F KCNJ8	1.80e-05	191	39	5	CID000002284
Drug	NSC759576	FOXM1 CACNA1A CACNA1D CACNA1E CACNA1F	1.80e-05	191	39	5	CID000003075
Drug	manidipine	CACNA1A CACNA1D CACNA1E CACNA1F	2.09e-05	95	39	4	CID000004008
Drug	Bufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A	SPTBN5 WHRN QPCTL AFF2 JAM3	2.14e-05	198	39	5	5515_UP
Drug	isotetrandrine	CACNA1A CACNA1D CACNA1E CACNA1F	2.27e-05	97	39	4	CID000005422
Drug	nitrendipine	CACNA1A CACNA1D CACNA1E CACNA1F	2.36e-05	98	39	4	CID000004507
Drug	isradipine	CACNA1A CACNA1D CACNA1E CACNA1F	2.56e-05	100	39	4	CID000003784
Drug	AC1NDT8D	SMARCA2 SMARCA4 JAM3	2.68e-05	34	39	3	CID004631220
Drug	loperamide	CACNA1A CACNA1D CACNA1E CACNA1F	3.10e-05	105	39	4	CID000003954
Drug	3,4-dihydroquinazoline	CACNA1A CACNA1E	4.27e-05	6	39	2	CID000583065
Drug	alpha-sialylcholesterol	CACNA1A CACNA1E	4.27e-05	6	39	2	CID000133976
Drug	lamotrigine	CACNA1A CACNA1D CACNA1E CACNA1F	4.58e-05	116	39	4	CID000003878
Drug	AC1NBU2S	CACNA1A CACNA1D CACNA1E CACNA1F	4.74e-05	117	39	4	CID004473765
Drug	APMPA	CACNA1A CACNA1E	5.97e-05	7	39	2	CID000512300
Drug	bepridil	CACNA1A CACNA1D CACNA1E CACNA1F	6.33e-05	126	39	4	CID000002351
Drug	amlodipine	CACNA1A CACNA1D CACNA1E CACNA1F	6.33e-05	126	39	4	CID000002162
Drug	pimozide	CACNA1A CACNA1D CACNA1E CACNA1F	6.53e-05	127	39	4	CID000016362
Drug	enzacamene	CACNA1A CACNA1D CACNA1E CACNA1F	6.94e-05	129	39	4	ctd:C038939
Drug	lanthanum	CACNA1A CACNA1D CACNA1E CACNA1F	8.52e-05	136	39	4	CID000023926
Drug	KW-3049	CACNA1A CACNA1D CACNA1F	8.61e-05	50	39	3	CID000002324
Drug	phorbol acetate myristate	FOXM1 SLC28A1 CACNA1A CACNA1D CACNA1E CACNA1F DGKZ ITGAV KCNJ8 S1PR4	9.15e-05	1399	39	10	CID000004792
Drug	octylmethoxycinnamate	CACNA1A CACNA1D CACNA1E CACNA1F	9.27e-05	139	39	4	ctd:C118580
Drug	Cinnarizine	CACNA1D CACNA1F	1.02e-04	9	39	2	DB00568
Drug	Nimodipine	CACNA1D CACNA1F	1.02e-04	9	39	2	DB00393
Drug	Dantrolene-13C3	CACNA1A CACNA1D CACNA1E CACNA1F	1.09e-04	145	39	4	CID000002951
Drug	nimodipine	CACNA1A CACNA1D CACNA1E CACNA1F	1.09e-04	145	39	4	CID000004497
Drug	nicardipine	CACNA1A CACNA1D CACNA1E CACNA1F	1.09e-04	145	39	4	CID000004473
Drug	Bay K 8644	CACNA1A CACNA1D CACNA1E CACNA1F	1.24e-04	150	39	4	CID000002303
Drug	Pesticides	CACNA1A CACNA1D PPP1R15A ITGAV	1.24e-04	150	39	4	ctd:D010575
Drug	procaine	CACNA1A CACNA1D CACNA1E CACNA1F	1.34e-04	153	39	4	CID000004914
Drug	lindane	FOXM1 CACNA1D CACNA1E CACNA1F	1.38e-04	154	39	4	CID000000727
Drug	butylparaben	CACNA1A CACNA1D CACNA1E CACNA1F	1.48e-04	157	39	4	ctd:C038091
Drug	Mibefradil	CACNA1D CACNA1F	1.56e-04	11	39	2	DB01388
Drug	leys	CACNA1A CACNA1E	1.56e-04	11	39	2	CID000484683
Drug	EGTA-AM	CACNA1A CACNA1D CACNA1E	1.64e-04	62	39	3	CID000121907
Drug	AC1L2VU3	CACNA1A CACNA1E	1.87e-04	12	39	2	CID000129572
Drug	gabapentin	CACNA1A CACNA1D CACNA1E CACNA1F	1.97e-04	169	39	4	CID000003446
Drug	felodipine	CACNA1A CACNA1D CACNA1E CACNA1F	1.97e-04	169	39	4	CID000003333
Drug	riluzole	CACNA1A CACNA1D CACNA1E CACNA1F	2.20e-04	174	39	4	CID000005070
Drug	papaverine	CACNA1A CACNA1D CACNA1E CACNA1F	2.30e-04	176	39	4	CID000004680
Drug	Prenylamine lactate [69-43-2]; Up 200; 9.6uM; PC3; HT_HG-U133A	SPTBN5 WHRN PPP1R15A AFF2	2.50e-04	180	39	4	5070_UP
Drug	AC1L1JG6	CACNA1A CACNA1D	2.57e-04	14	39	2	CID000005026
Drug	AC1L1KC5	FOXM1 CACNA1A CACNA1D CACNA1E CACNA1F PPP1R15A	2.93e-04	541	39	6	CID000005428
Drug	Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	WHRN RIN1 AVPI1 GPATCH1	2.95e-04	188	39	4	7124_UP
Drug	butamben	CACNA1A CACNA1E	2.96e-04	15	39	2	CID000002482
Drug	FPL 64176	FOXM1 CACNA1D	2.96e-04	15	39	2	CID000003423
Drug	Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A	CACNA1A CACNA1D RIN1 PPP1R15A	3.20e-04	192	39	4	4152_DN
Drug	dihydropyridine	CACNA1A CACNA1D CACNA1E CACNA1F	3.26e-04	193	39	4	CID000104822
Drug	pentasulfane	CACNA1A CACNA1E	3.38e-04	16	39	2	CID000448216
Drug	Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; HL60; HT_HG-U133A	CACNA1A RIN1 ZNF671 AVPI1	3.39e-04	195	39	4	1330_DN
Drug	felodipine; Up 200; 10uM; MCF7; HG-U133A	SLC28A1 CACNA1A CACNA1E KCNJ8	3.53e-04	197	39	4	337_UP
Drug	Rolipram [61413-54-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A	SPTBN5 WHRN GPATCH2L JAM3	3.53e-04	197	39	4	6449_UP
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	SMARCA2 RIN1 PPP1R15A GPATCH1	3.53e-04	197	39	4	2075_UP
Drug	pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A	SMARCA2 GPATCH2L KCNJ8 JAM3	3.53e-04	197	39	4	5972_UP
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A	SLC28A1 SPTBN5 CACNA1D KCNJ8	3.60e-04	198	39	4	4374_UP
Drug	Nisoxetine hydrochloride [57754-86-6]; Down 200; 13uM; HL60; HT_HG-U133A	SMARCA4 CACNA1A RIN1 S1PR4	3.60e-04	198	39	4	3117_DN
Drug	Ethionamide [536-33-4]; Down 200; 24uM; PC3; HT_HG-U133A	WHRN CACNA1A PPP1R15A KCNJ8	3.67e-04	199	39	4	4593_DN
Drug	gadolinium	CACNA1A CACNA1D CACNA1E CACNA1F	3.67e-04	199	39	4	CID000023982
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A	WHRN QPCTL AFF2 GPATCH2L	3.67e-04	199	39	4	4741_DN
Drug	D-myo-inositol-1,4,5-triphosphate	FOXM1 CACNA1A CACNA1D CACNA1E CACNA1F DGKZ	3.80e-04	568	39	6	CID000000806
Drug	myo-inositol	FOXM1 CACNA1A CACNA1D CACNA1E CACNA1F DGKZ S1PR4	4.03e-04	811	39	7	CID000000892
Drug	guanosine 3',5'-cyclic monophosphoric acid	SMARCA2 SMARCA4 CACNA1A CACNA1D CACNA1E CACNA1F	4.13e-04	577	39	6	CID000000295
Drug	N6-Me-dAdo	CACNA1A CACNA1E	4.80e-04	19	39	2	CID000168948
Drug	pranidipine	CACNA1A CACNA1E	4.80e-04	19	39	2	CID006436048
Drug	cobalt-60	CACNA1A CACNA1D POP7 CACNA1E CACNA1F	5.12e-04	390	39	5	CID000061492
Drug	phenytoin	CACNA1A CACNA1D CACNA1E CACNA1F	5.26e-04	219	39	4	CID000001775
Disease	familial hemiplegic migraine 1 (implicated_via_orthology)	CACNA1A CACNA1E	4.84e-06	3	38	2	DOID:0111181 (implicated_via_orthology)
Disease	migraine (implicated_via_orthology)	CACNA1A CACNA1E	9.67e-06	4	38	2	DOID:6364 (implicated_via_orthology)
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1D CACNA1F	9.67e-06	4	38	2	DOID:0060173 (implicated_via_orthology)
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	SMARCA2 SMARCA4	1.61e-05	5	38	2	C3281201
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A CACNA1E	3.38e-05	7	38	2	DOID:0050951 (implicated_via_orthology)
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA2 SMARCA4	5.78e-05	9	38	2	DOID:0050340 (implicated_via_orthology)
Disease	Coffin-Siris syndrome	SMARCA2 SMARCA4	1.25e-04	13	38	2	C0265338
Disease	Sinus Node Dysfunction (disorder)	CACNA1D KCNJ8	1.68e-04	15	38	2	C0428908
Disease	sciatic neuropathy (biomarker_via_orthology)	CACNA1D KCNJ8 JAM3	2.84e-04	99	38	3	DOID:11446 (biomarker_via_orthology)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1D CACNA1F	9.90e-04	36	38	2	DOID:11723 (implicated_via_orthology)
Disease	aspirin use measurement	SMARCA4 PCNX3	1.16e-03	39	38	2	EFO_0007013

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRTLRAVRVLRPLKL	CACNA1A	191	O00555
LRTLRAVRVLRPLKL	CACNA1E	186	Q15878
LLLRPVKLLRRRFRL	B4GALNT3	11	Q6L9W6
LRLQRSPVLKRRPKL	CARMIL2	1376	Q6F5E8
RPLLSLIREKARPRP	AFF2	586	P51816
RVAEALKRLRRKRPP	AVPI1	66	Q5T686
PRKASLLPLQRLRRR	ANKRD33B	401	A6NCL7
KRRLLPRVRLLPLLL	QPCTL	26	Q9NXS2
KILRVLRVLRPLRAI	CACNA1F	966	O60840
RKARPQLILSRRPRR	NOL9	21	Q5SY16
NLRKPRIRDRLPKAR	KCNJ8	21	Q15842
PQELLRRLKSLPLRR	GPATCH1	916	Q9BRR8
LALLRPSKRQPPLRR	PCNX3	386	Q9H6A9
MALRRPPRLRLCARL	JAM3	1	Q9BX67
LMLRGLRRLRELRLP	LRIT1	101	Q9P2V4
TLRKRLPSRLPRRPN	POP7	21	O75817
IYKLKLRPRIRPRRD	GAS2L2	771	Q8NHY3
RRRPLLRLPRRTPAK	FBXL17	26	Q9UF56
RRRLRLGPRGLPLLL	ITGAV	6	P06756
LPKPRMRGLLARRLR	COX6C	6	P09669
RRPLILKRRRLPLPV	FOXM1	6	Q08050
APCRPLRRRRKVKRV	GPATCH2L	121	Q9NWQ4
VLRRKALAPRLLLRL	CLPB	6	Q9H078
APRRLNKRRFPGLRL	DGKZ	36	Q13574
FLRALRKLPRPVRGL	DNAH10	1301	Q8IVF4
KAPRPAARRKARRLL	S1PR4	236	O95977
KILRVLRVLRPLRAI	CACNA1D	981	Q01668
RLPLRLQRRLKRPET	PPP1R15A	526	O75807
RRLPRELKIRVRKLQ	POLR3GL	111	Q9BT43
LKPLRPILAARLRRR	RIN1	441	Q13671
RRLHKVLRPFLLRRL	SMARCA2	936	P51531
RRLHKVLRPFLLRRL	SMARCA4	966	P51532
VKRRLLPMLRLVIPR	WHRN	86	Q9P202
RLKTLRRPRVRDRLP	SPTBN5	2111	Q9NRC6
RKCLRPRSRRLPLPA	ZNF671	16	Q8TAW3
NPRARKKRSRIPLLR	SPDYE5	296	A6NIY4
LRIFRIPRRPRKLTL	FERMT3	356	Q86UX7
ARRRRKRLRQDPPLI	IGSF9	766	Q9P2J2
RLLKRLLGPKLRRFL	SLC28A1	126	O00337