Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

THBD THBS2 EYS FBN2 CABP7 EGF PCDHB14 PCDHB13 PCDHB11 PCDHB8 EFCAB2 PITPNM3 PCDHB3 LRP2 LRP4 ADGRE1 LTBP4 PCDHB16 CRB2

2.16e-107498419GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FRAS1 THBS2 FBN2 COL16A1 COL22A1 LTBP4 SSPOP

1.44e-05188847GO:0005201
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

8.05e-0853856GO:0016339
GeneOntologyBiologicalProcesssynapse assembly

THBS2 PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 LRP4 PCDHB16

4.01e-05308858GO:0007416
GeneOntologyCellularComponentextracellular matrix

FRAS1 THBS2 EYS IL16 FCGBP FBN2 COL16A1 ZAN TNN ADAMTS18 COL22A1 ADAMTS8 LTBP4 SSPOP

4.41e-076568614GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

FRAS1 THBS2 EYS IL16 FCGBP FBN2 COL16A1 ZAN TNN ADAMTS18 COL22A1 ADAMTS8 LTBP4 SSPOP

4.58e-076588614GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

FRAS1 THBS2 EYS IL16 FBN2 COL16A1 TNN COL22A1 ADAMTS8 LTBP4 SSPOP

1.10e-055308611GO:0062023
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type II

BECN2 BECN1

9.98e-054862GO:0034272
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type I

BECN2 BECN1

9.98e-054862GO:0034271
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III

BECN2 BECN1

3.47e-047862GO:0035032
GeneOntologyCellularComponentphagophore assembly site

BECN2 RB1CC1 BECN1

5.52e-0439863GO:0000407
GeneOntologyCellularComponentmicrofibril

FBN2 LTBP4

1.27e-0313862GO:0001527
DomainEGF

THBD FRAS1 THBS2 EYS FCGBP FBN2 MALRD1 EGF ZAN TNN LRP2 LRP4 ASTN1 ADGRE1 LTBP4 CRB2

1.05e-142358616SM00181
DomainEGF-like_dom

THBD FRAS1 THBS2 EYS FCGBP FBN2 MALRD1 EGF ZAN TNN LRP2 LRP4 ASTN1 ADGRE1 LTBP4 CRB2

2.59e-142498616IPR000742
DomainEGF_3

THBD THBS2 EYS FBN2 MALRD1 EGF ZAN TNN LRP2 LRP4 ASTN1 ADGRE1 LTBP4 SSPOP CRB2

1.98e-132358615PS50026
DomainEGF_1

THBD THBS2 EYS FBN2 MALRD1 EGF ZAN TNN LRP2 LRP4 ASTN1 ADGRE1 LTBP4 SSPOP CRB2

6.50e-132558615PS00022
DomainEGF_2

THBD THBS2 EYS FBN2 MALRD1 EGF ZAN TNN LRP2 LRP4 ASTN1 ADGRE1 LTBP4 SSPOP CRB2

1.13e-122658615PS01186
DomainEGF-like_CS

THBD THBS2 EYS FBN2 MALRD1 EGF ZAN TNN LRP2 LRP4 ASTN1 ADGRE1 LTBP4 CRB2

1.42e-112618614IPR013032
DomainEGF_CA

THBD THBS2 EYS FBN2 EGF LRP2 LRP4 ADGRE1 LTBP4 CRB2

2.27e-101228610SM00179
DomainEGF-like_Ca-bd_dom

THBD THBS2 EYS FBN2 EGF LRP2 LRP4 ADGRE1 LTBP4 CRB2

2.67e-101248610IPR001881
DomainEGF_Ca-bd_CS

THBD EYS FBN2 EGF LRP2 LRP4 ADGRE1 LTBP4 CRB2

6.23e-1097869IPR018097
DomainEGF_CA

THBD EYS FBN2 EGF LRP2 LRP4 ADGRE1 LTBP4 CRB2

7.49e-1099869PS01187
DomainASX_HYDROXYL

THBD EYS FBN2 EGF LRP2 LRP4 ADGRE1 LTBP4 CRB2

8.20e-10100869PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

THBD EYS FBN2 EGF LRP2 LRP4 ADGRE1 LTBP4 CRB2

1.38e-09106869IPR000152
DomainGrowth_fac_rcpt_

THBD FRAS1 EYS FBN2 EGF TNN LRP2 LRP4 ADGRE1 LTBP4

2.54e-091568610IPR009030
DomainEGF_CA

THBD THBS2 FBN2 EGF LRP2 LRP4 ADGRE1 LTBP4

5.74e-0986868PF07645
DomainEGF

THBD THBS2 EYS MALRD1 EGF ZAN LRP2 LRP4 CRB2

6.44e-09126869PF00008
DomainCadherin_C

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

3.67e-0842866IPR032455
DomainCadherin_C_2

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

3.67e-0842866PF16492
DomaincEGF

THBD FBN2 LRP2 LRP4 ADGRE1

1.12e-0726865IPR026823
DomaincEGF

THBD FBN2 LRP2 LRP4 ADGRE1

1.12e-0726865PF12662
DomainTIL_dom

FCGBP ZAN LRP2 SSPOP

4.05e-0714864IPR002919
DomainTSP_1

THBS2 CILP2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

4.40e-0763866PF00090
DomainTSP1

THBS2 CILP2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

5.31e-0765866SM00209
DomainTSP1_rpt

THBS2 CILP2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

5.31e-0765866IPR000884
DomainTSP1

THBS2 CILP2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

5.31e-0765866PS50092
DomainCadherin_2

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

5.31e-0765866PF08266
DomainCadherin_N

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

5.31e-0765866IPR013164
DomainVWC

FRAS1 THBS2 FCGBP ZAN SSPOP

8.20e-0738865SM00214
DomainVWF_dom

FRAS1 THBS2 FCGBP ZAN SSPOP

1.37e-0642865IPR001007
DomainVWC_out

FRAS1 FCGBP ZAN SSPOP

1.54e-0619864SM00215
DomainLdl_recept_a

MALRD1 LRP2 LRP4 TMPRSS4 SSPOP

1.95e-0645865PF00057
Domain-

MALRD1 LRP2 LRP4 TMPRSS4 SSPOP

2.17e-06468654.10.400.10
DomainLDLRA_1

MALRD1 LRP2 LRP4 TMPRSS4 SSPOP

2.70e-0648865PS01209
DomainLDLRA_2

MALRD1 LRP2 LRP4 TMPRSS4 SSPOP

2.99e-0649865PS50068
DomainLDrepeatLR_classA_rpt

MALRD1 LRP2 LRP4 TMPRSS4 SSPOP

2.99e-0649865IPR002172
DomainLDLa

MALRD1 LRP2 LRP4 TMPRSS4 SSPOP

2.99e-0649865SM00192
DomainLaminin_G

THBS2 EYS COL16A1 COL22A1 CRB2

6.96e-0658865IPR001791
DomainConA-like_dom

THBS2 EYS MALRD1 COL16A1 ZAN COL22A1 MEFV CRB2

7.61e-06219868IPR013320
DomainCadherin_CS

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.11e-05109866IPR020894
DomainCADHERIN_1

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.36e-05113866PS00232
DomainCadherin

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.36e-05113866PF00028
DomainCADHERIN_2

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.43e-05114866PS50268
Domain-

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.43e-051148662.60.40.60
DomainCA

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.50e-05115866SM00112
DomainCadherin-like

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.58e-05116866IPR015919
DomainCadherin

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.74e-05118866IPR002126
DomainTIL

FCGBP ZAN SSPOP

2.01e-0512863PF01826
DomainC8

FCGBP ZAN SSPOP

2.01e-0512863PF08742
DomainAtg6/Beclin

BECN2 BECN1

2.10e-052862IPR007243
DomainAPG6

BECN2 BECN1

2.10e-052862PF04111
DomainVWFC_1

FRAS1 THBS2 ZAN SSPOP

2.21e-0536864PS01208
DomainUnchr_dom_Cys-rich

FCGBP ZAN SSPOP

2.61e-0513863IPR014853
DomainC8

FCGBP ZAN SSPOP

2.61e-0513863SM00832
DomainVWFC_2

FRAS1 THBS2 ZAN SSPOP

2.74e-0538864PS50184
DomainLdl_recept_b

EGF LRP2 LRP4

3.31e-0514863PF00058
DomainLDLRB

EGF LRP2 LRP4

3.31e-0514863PS51120
DomainLDLR_class-A_CS

MALRD1 LRP2 LRP4 SSPOP

3.37e-0540864IPR023415
DomainLY

EGF LRP2 LRP4

4.12e-0515863SM00135
DomainLDLR_classB_rpt

EGF LRP2 LRP4

4.12e-0515863IPR000033
DomainVWD

FCGBP ZAN SSPOP

5.05e-0516863SM00216
DomainVWF_type-D

FCGBP ZAN SSPOP

5.05e-0516863IPR001846
DomainVWFD

FCGBP ZAN SSPOP

5.05e-0516863PS51233
DomainVWD

FCGBP ZAN SSPOP

5.05e-0516863PF00094
DomainTILa

FCGBP ZAN

6.27e-053862PF12714
DomainTILa_dom

FCGBP ZAN

6.27e-053862IPR025615
DomainTSPN

THBS2 COL16A1 COL22A1

1.56e-0423863SM00210
DomainhEGF

EYS FBN2 CRB2

2.84e-0428863PF12661
DomainTB

FBN2 LTBP4

4.34e-047862PF00683
DomainMARCH-like

MARCHF8 MARCHF1

5.76e-048862IPR033275
Domain-

FBN2 LTBP4

5.76e-0488623.90.290.10
DomainTB

FBN2 LTBP4

7.39e-049862PS51364
DomainTB_dom

FBN2 LTBP4

7.39e-049862IPR017878
Domain-

EGF LRP2 LRP4

7.64e-04398632.120.10.30
Domain-

THBS2 EYS COL16A1 CRB2

9.70e-04958642.60.120.200
DomainRINGv

MARCHF8 MARCHF1

1.12e-0311862PF12906
DomainZF_RING_CH

MARCHF8 MARCHF1

1.12e-0311862PS51292
Domain6-blade_b-propeller_TolB-like

EGF LRP2 LRP4

1.24e-0346863IPR011042
DomainZnf_RING-CH

MARCHF8 MARCHF1

2.72e-0317862IPR011016
DomainRINGv

MARCHF8 MARCHF1

2.72e-0317862SM00744
DomainMAM

MALRD1 ZAN

2.72e-0317862SM00137
DomainMAM

MALRD1 ZAN

3.06e-0318862PF00629
DomainMAM_dom

MALRD1 ZAN

3.06e-0318862IPR000998
DomainMAM_2

MALRD1 ZAN

3.06e-0318862PS50060
Domainzf-C3HC4

TRIM28 MARCHF8 RNF213 LNX1 MARCHF1

3.69e-03223865PF00097
DomainZnf_RING

TRIM28 MARCHF8 RNF213 IRF2BPL LNX1 MARCHF1

3.94e-03326866IPR001841
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THBS2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

8.41e-0739645M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THBS2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

8.41e-0739645MM15165
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

ITGA11 FBN2 COL16A1 TNN LRP4 ADAMTS18 COL22A1 ADAMTS8 LTBP4

7.83e-06300649M610
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THBS2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

1.38e-0568645M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

THBS2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

1.34e-04109645MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

THBS2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

1.46e-04111645M27416
Pubmed

Protocadherins.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

3.24e-131386612231349
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

7.22e-122086611322959
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

6.28e-095786632633719
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

6.99e-095886630377227
Pubmed

Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.

PCDHB13 PCDHB11 PCDHB8 PCDHB3

7.23e-091086422969705
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

1.85e-086886611230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

2.62e-087286610380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

3.10e-087486610817752
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

THBS2 CILP2 SEMA5B ADAMTS18 ADAMTS8 SSPOP

3.36e-087586620637190
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

3.94e-087786610835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

4.97e-088086610716726
Pubmed

A unique role of cohesin-SA1 in gene regulation and development.

PCDHB14 PCDHB13 PCDHB8 PCDHB16

6.20e-081686422415368
Pubmed

Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.

PCDHB13 PCDHB11 PCDHB8 PCDHB3

8.09e-081786418279309
Pubmed

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

PCDHB14 PCDHB13 PCDHB8 PCDHB16

1.31e-071986423920377
Pubmed

Identification of novel cadherins expressed in human melanoma cells.

PCDHB14 PCDHB11 PCDHB16

5.07e-0778639182820
Pubmed

Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.

PCDHB13 PCDHB8 PCDHB3 PCDHB16

6.82e-072886433523829
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

IL16 EGF MCM8 LRP2 PPP1R15A LTBP4 TP53BP2 FANCA

1.14e-0631386820800603
Pubmed

CRISPR/Cas9-Mediated Disruption of ZNF543 Gene: An Approach Toward Discovering Its Relation to TRIM28 Gene in Parkinson's Disease.

TRIM28 ZNF543

6.04e-06286235467255
Pubmed

Succination inactivates gasdermin D and blocks pyroptosis.

GSDMD MEFV

6.04e-06286232820063
Pubmed

ZBTB38, a novel regulator of autophagy initiation targeted by RB1CC1/FIP200 in spinal cord injury.

ZBTB38 RB1CC1

6.04e-06286230075197
Pubmed

Downregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiation.

BECN1 TP53BP2

6.04e-06286227929538
Pubmed

Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy.

BECN2 BECN1

6.04e-06286236719945
Pubmed

Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer.

BECN2 BECN1

6.04e-06286226506105
Pubmed

MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.

MARCHF8 MARCHF1

6.04e-06286221757542
Pubmed

Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis.

BECN2 BECN1

6.04e-06286226929373
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

FBN2 ADAMTS18 ADGRE1

1.16e-051886339040056
Pubmed

Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids.

BECN2 BECN1

1.81e-05386227305347
Pubmed

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection.

MARCHF8 MARCHF1

1.81e-05386227503069
Pubmed

TRPM3 is a nociceptor channel involved in the detection of noxious heat.

TRPV1 TRPM3

1.81e-05386221555074
Pubmed

Membrane-associated RING-CH (MARCH) 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor.

MARCHF8 MARCHF1

1.81e-05386223606747
Pubmed

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

RB1CC1 BECN1

1.81e-05386223685627
Pubmed

Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways.

TRPV1 BECN1

1.81e-05386222753949
Pubmed

Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.

MARCHF8 MARCHF1

1.81e-05386238299743
Pubmed

Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.

ADAMTS18 ADAMTS8

1.81e-05386228814085
Pubmed

Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.

MARCHF8 MARCHF1

1.81e-05386223300075
Pubmed

Upregulation of TRPM3 in nociceptors innervating inflamed tissue.

TRPV1 TRPM3

1.81e-05386232880575
Pubmed

A TRP channel trio mediates acute noxious heat sensing.

TRPV1 TRPM3

1.81e-05386229539642
Pubmed

Reactive Oxygen Species-Mediated c-Jun NH2-Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction.

BECN2 BECN1

1.81e-05386228515304
Pubmed

Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.

TRPV1 TRPM3

1.81e-05386225733887
Pubmed

An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system.

BECN2 BECN1

1.81e-05386233608268
Pubmed

Intraperitoneal administration of recombinant receptor-associated protein causes phosphaturia via an alteration in subcellular distribution of the renal sodium phosphate co-transporter.

SLC34A1 LRP2

1.81e-05386215976002
Pubmed

Impaired PTH-induced endocytotic down-regulation of the renal type IIa Na+/Pi-cotransporter in RAP-deficient mice with reduced megalin expression.

SLC34A1 LRP2

1.81e-05386212748857
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

IL16 FBN2 MCM8 TRIM28 TAF7L LRP2 LRP4 RNF213 ZNF740 VPS51 MGA LTBP4

1.93e-051116861231753913
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

NUDT18 KMT2B LRP2 LNX1 BECN1 LTBP4 SSPOP DKK3 TP53BP2

2.00e-0560886916713569
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN2 LTBP4

3.61e-05486212429738
Pubmed

Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.

MARCHF8 MARCHF1

3.61e-05486227503071
Pubmed

The HLA-DRalpha chain is modified by polyubiquitination.

MARCHF8 MARCHF1

3.61e-05486219117940
Pubmed

Francisella induced microparticulate caspase-1/gasdermin-D activation is regulated by NLRP3 independent of Pyrin.

GSDMD MEFV

3.61e-05486230596757
Pubmed

ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis.

RB1CC1 BECN1

3.61e-05486233931087
Pubmed

CHOP mediates ASPP2-induced autophagic apoptosis in hepatoma cells by releasing Beclin-1 from Bcl-2 and inducing nuclear translocation of Bcl-2.

BECN1 TP53BP2

3.61e-05486225032846
Pubmed

Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice.

BECN1 DKK3

3.61e-05486228407687
Pubmed

Beclin 2 negatively regulates innate immune signaling and tumor development.

BECN2 BECN1

3.61e-05486232865519
Pubmed

Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.

SLC34A1 LRP2 ADGRE1

4.57e-052886328847650
Pubmed

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.

BECN2 BECN1

6.01e-05586230842662
Pubmed

The Sensory Coding of Warm Perception.

TRPV1 TRPM3

6.01e-05586232208171
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP2 LRP4

6.01e-05586219047013
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KMT2B ASTN1 RB1CC1 FBXW11

6.63e-058786412465718
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

FBN2 COL16A1 COL22A1 LTBP4 SSPOP

7.63e-0517586528071719
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

KMT2B TRPM3 PCDHB14 NELFB PITPNM3 LRP2 RNF213 SSPOP FANCA

8.73e-0573686929676528
Pubmed

Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor.

EGF DGKQ

9.01e-05686222732145
Pubmed

A synaptic temperature sensor for body cooling.

TRPV1 TRPM3

9.01e-05686234672983
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TRPM3 MED12L RNF213 PCDHB16

1.19e-0410186410997877
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

FBN2 TNN

1.68e-04886223055981
Pubmed

Common variants in the trichohyalin gene are associated with straight hair in Europeans.

FRAS1 EGF

1.68e-04886219896111
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

THBD THBS2 COL16A1 SEMA5B ADAMTS8

1.79e-0421086516537572
Pubmed

Congenital Diaphragmatic Hernia Overview

FRAS1 LRP2 LTBP4

2.05e-044686320301533
Pubmed

Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins.

GSDMD MEFV

2.15e-04986236417874
Pubmed

LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

RB1CC1 BECN1

2.68e-041086231257024
Pubmed

Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes.

RB1CC1 BECN1

2.68e-041086231959973
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

IL16 COL16A1 TRPM3 NELFB IRF2BPL COL22A1 MGA DIS3

3.11e-0468986836543142
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SCYL2 ZBTB38 LRP2 LRP4 ASTN1 ADAMTS8 LNX1 BECN1 DKK3 MITD1 FBXW11

3.25e-041285861135914814
Pubmed

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation.

RB1CC1 BECN1

3.28e-041186226764599
Pubmed

Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.

GSDMD MEFV

3.28e-041186232298652
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP2 LRP4

3.28e-041186224639464
Pubmed

MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy.

RB1CC1 BECN1

3.28e-041186228059666
Pubmed

The IgLON family of cell adhesion molecules expressed in developing neural circuits ensure the proper functioning of the sensory system in mice.

TRPV1 TRPM3

3.28e-041186239349721
Pubmed

Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera.

EGF LTBR ADGRE1

3.49e-045586310926756
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

THBS2 FBN2 COL16A1 LTBP4

3.60e-0413586428675934
Pubmed

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy.

TRIM28 BECN1

3.93e-041286223569248
Pubmed

Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis.

GSDMD MEFV

3.93e-041286230451870
Pubmed

Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.

PCDHB11 PCDHB3 PCDHB16

4.29e-045986323754746
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

ADGRG3 EGF ADGRE1 LTBP4

4.48e-0414386420424473
Pubmed

Overexpression of integrin α11 induces cardiac fibrosis in mice.

ITGA11 ADGRE1

4.63e-041386228771943
Pubmed

Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice.

CABP7 LRP4

5.39e-041486238327785
Pubmed

The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology.

COL16A1 TNN

5.39e-041486232541010
Pubmed

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock.

RB1CC1 BECN1

5.39e-041486231346084
Pubmed

The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1.

RB1CC1 BECN1

5.39e-041486231806350
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

FRAS1 ADAMTS8 SSPOP

5.45e-046486322261194
Pubmed

The E3 ubiquitin ligase APC/CCdh1 degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.

SMOX MITD1 FBXW11

5.71e-046586329150431
Pubmed

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

RB1CC1 BECN1

6.21e-041586229056340
Pubmed

Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation.

THBS2 DKK3

6.21e-041586220458143
Pubmed

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

RB1CC1 BECN1

6.21e-041586230245008
Pubmed

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.

NUDT18 MOXD1 COL22A1 SMOX

6.21e-0415686422008794
Pubmed

Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.

MARCHF8 MARCHF1

7.09e-041686214722266
Pubmed

Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling.

SLC34A1 DKK3

7.09e-041686221354128
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

FBN2 LRP2 SSPOP

7.39e-047186333541421
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FRAS1 IL16 COL16A1 LTBP4

8.02e-0416786422159717
Pubmed

Wnt signaling in the murine diastema.

LRP4 DKK3

8.02e-041786221531785
Pubmed

Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development.

CNMD LTBP4

8.02e-041786228898113
Pubmed

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.

RB1CC1 BECN1

8.02e-041786221241894
InteractionNTN5 interactions

FRAS1 FBN2 LRP2 LRP4 LTBP4

5.02e-0824865int:NTN5
InteractionPCDHB13 interactions

PCDHB13 PCDHB11 PCDHB3

7.46e-075863int:PCDHB13
InteractionZNF224 interactions

FBN2 TRIM28 LRP2 LRP4

1.42e-0620864int:ZNF224
InteractionZFP41 interactions

FRAS1 FBN2 LRP2 LRP4 LTBP4

4.42e-0657865int:ZFP41
InteractionZNF563 interactions

TRIM28 LRP4 LTBP4

1.61e-0512863int:ZNF563
InteractionZNF408 interactions

FRAS1 FBN2 ZBTB8B LRP2 LRP4 LTBP4

3.66e-05145866int:ZNF408
InteractionKHDRBS3 interactions

NUDT18 PCDHB14 NELFB LNX1 FBXW11

5.13e-0594865int:KHDRBS3
Cytoband5q31

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

8.65e-081158665q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

2.16e-05298866chr5q31
GeneFamilyClustered protocadherins

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3 PCDHB16

8.15e-086462620
GeneFamilyRing finger proteins|Membrane associated ring-CH-type fingers

MARCHF8 MARCHF1

6.24e-041162260
GeneFamilyLow density lipoprotein receptors

LRP2 LRP4

8.81e-0413622634
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS18 ADAMTS8

1.91e-031962250
GeneFamilyRing finger proteins

TRIM28 MARCHF8 RNF213 LNX1 MARCHF1

2.51e-0327562558
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TRIM28 RB1CC1 PPP1R15A TP53BP2

3.45e-03181624694
GeneFamilyTransient receptor potential cation channels

TRPV1 TRPM3

4.13e-0328622249
GeneFamilyAutophagy related

RB1CC1 BECN1

5.71e-03336221022
CoexpressionNABA_CORE_MATRISOME

FRAS1 THBS2 EYS CILP2 FBN2 COL16A1 TNN COL22A1 LTBP4 SSPOP

2.15e-082758510M5884
CoexpressionNABA_CORE_MATRISOME

FRAS1 THBS2 CILP2 FBN2 COL16A1 TNN COL22A1 LTBP4 SSPOP

2.38e-07270859MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 THBS2 EYS CILP2 FBN2 TNN LTBP4 SSPOP

2.49e-07196858M3008
CoexpressionNABA_MATRISOME

FRAS1 THBS2 EYS IL16 CILP2 FBN2 COL16A1 EGF SEMA5B TNN ADAMTS18 COL22A1 ADAMTS8 LTBP4 SSPOP

9.70e-0710268515M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 THBS2 CILP2 FBN2 TNN LTBP4 SSPOP

2.99e-06191857MM17059
CoexpressionNABA_MATRISOME

FRAS1 THBS2 IL16 CILP2 FBN2 COL16A1 EGF SEMA5B TNN ADAMTS18 COL22A1 ADAMTS8 LTBP4 SSPOP

4.22e-0610088514MM17056
CoexpressionGSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_UP

DENND4A FCGBP ZBTB8B LRP2 RDM1 ZNF543

3.65e-05190856M9871
CoexpressionWANG_MLL_TARGETS

THBD THBS2 FBN2 DEF6 PCDHB13 PCDHB8 DKK3

6.25e-05306857MM1076
CoexpressionAtlasratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3

CABP7 TRPM3 PCDHB13 PCDHB11 PCDHB8 LRP2 ADAMTS18 COL22A1 SSPOP CRB2

1.67e-054718410ratio_ECTO_vs_SC_1000_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500

THBS2 COL16A1 SEMA5B GSDMD TNN PCDHB8 RNF213 ASTN1 LTBP4 FANCA

2.30e-054898410Facebase_RNAseq_e8.5_Paraxial Mesoderm_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#1

ITGA11 THBS2 MOXD1 DENND4A COL16A1 GSDMD TNN DEF6 PCDHB8 RNF213 ALAS1 DKK3 FANCA

3.90e-058788413Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K1
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#4

THBS2 COL16A1 GSDMD TNN PCDHB8 RNF213 FANCA

4.79e-05241847Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#5

THBS2 COL16A1 GSDMD TNN PCDHB8 RNF213 FANCA

5.18e-05244847Facebase_RNAseq_e9.5_Olfactory Placode_1000_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#3

THBS2 COL16A1 GSDMD TNN PCDHB8 RNF213 FANCA

5.89e-05249847Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K3
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

FRAS1 THBS2 MOXD1 COL16A1 SEMA5B GSDMD TNN PCDHB8 RNF213 ASTN1 LTBP4 DKK3 FANCA

1.09e-049728413Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5

THBS2 COL16A1 GSDMD TNN PCDHB8 RNF213 FANCA

1.12e-04276847Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

THBS2 COL16A1 SEMA5B GSDMD TNN PCDHB8 MED12L LRP2 RNF213 ASTN1 IRF2BPL LTBP4 FANCA

1.24e-049848413Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#4

ITGA11 THBS2 MOXD1 VPS13D DENND4A GSDMD DEF6 RNF213 ALAS1 DKK3 FANCA

1.41e-047318411Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4

THBS2 COL16A1 GSDMD TNN PCDHB8 RNF213 FANCA

1.80e-04298847Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4
CoexpressionAtlasMyeloid Cells, GN.Arth.SynF, CD11b+ Ly6-G+, Synovial Fluid, avg-3

THBD DENND4A ADGRG3 ALAS1 PPP1R15A ADGRE1 SMOX MEFV

2.49e-04418848GSM854338_500
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_k-means-cluster#2_top-relative-expression-ranked_200

EGF SLC34A1 LRP2

2.99e-0433843gudmap_kidney_adult_RenalCortexMixed_Std_k2_200
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_100

EGF SLC34A1 LRP2

3.57e-0435843gudmap_kidney_adult_JuxtaGlom_Ren1_k4_100
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000

FRAS1 THBS2 COL16A1 SEMA5B GSDMD TNN PCDHB8 RNF213 ASTN1 SMOX LTBP4 FANCA

4.08e-049678412Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000

THBS2 MOXD1 COL16A1 SEMA5B GSDMD TNN PCDHB8 PDXP RNF213 ASTN1 LTBP4 FANCA

4.08e-049678412Facebase_RNAseq_e9.5_Maxillary Arch_1000
CoexpressionAtlasPP_RBC_top-relative-expression-ranked_2500_k-means-cluster#3

PCDHB14 PCDHB13 PCDHB11 PCDHB8 PCDHB3

4.12e-04158845PP_RBC_2500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

FRAS1 THBS2 COL16A1 GSDMD TNN PCDHB8 LRP2 RNF213 ASTN1 IRF2BPL LTBP4 FANCA

4.31e-049738412Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

THBS2 COL16A1 SEMA5B GSDMD TNN PCDHB8 PDXP LRP2 RNF213 ASTN1 LTBP4 FANCA

4.44e-049768412Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000

THBS2 COL16A1 SEMA5B GSDMD TNN PCDHB8 RNF213 ASTN1 PPP1R15A BECN1 LTBP4 FANCA

4.52e-049788412Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_500

MOXD1 COL16A1 CNMD PCDHB11

4.89e-0492844gudmap_developingGonad_e16.5_epididymis_500_k1
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

CABP7 TRPM3 CNMD PCDHB13 ZBTB8B PCDHB8 MED12L LRP2 ADAMTS18 TMPRSS4 ASTN1 CRB2

5.08e-049918412PCBC_ECTO_fibroblast_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4

ITGA11 THBS2 DENND4A GSDMD DEF6 RNF213 ALAS1 DKK3 FANCA

5.43e-04591849Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#2

ITGA11 MOXD1 DENND4A GSDMD DEF6 RNF213 ALAS1 DKK3 FANCA

5.76e-04596849Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K2
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_200

EGF SLC34A1 LRP2

6.13e-0442843gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_200
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5

ITGA11 MOXD1 VPS13D DENND4A GSDMD DEF6 RNF213 ALAS1 DKK3 FANCA

6.30e-047348410Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1

THBS2 DENND4A FBN2 COL16A1 SEMA5B GSDMD DEF6 PCDHB8 MED12L ASTN1 LTBP4 DKK3 PCDHB16

6.37e-0411668413facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1
CoexpressionAtlasMesoderm Day 15-method_episomal_vs_Mesoderm Day 15-method_NA-Confounder_removed-fold2.0_adjp0.05

THBD LRP2 ADAMTS18 COL22A1

6.69e-04100844PCBC_ratio_MESO-15_from-episomal_vs_MESO-15_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 15-reprogram_OSK-L-l-p53KD_vs_Mesoderm Day 15-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

THBD LRP2 ADAMTS18 COL22A1

6.69e-04100844PCBC_ratio_MESO-15_from-OSK-L-l-p53KD_vs_MESO-15_from-ESC_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2

THBS2 SEMA5B ASTN1 LTBP4

6.69e-04100844Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

ITGA11 THBS2 MOXD1 DENND4A GSDMD DEF6 RNF213 ALAS1 DKK3 FANCA

6.99e-047448410Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FBN2 ZAN TRPM3 LRP2 COL22A1 SSPOP

6.98e-081848672cbed6462fea2622871bb7e49b0df3d984239281
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

ITGA11 THBS2 MOXD1 CILP2 COL16A1 TNN DKK3

6.98e-081848670b336489c10e8c3c957795dd845454f03404382b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FBN2 ZAN TRPM3 LRP2 COL22A1 SSPOP

6.98e-08184867ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FBN2 ZAN TRPM3 LRP2 COL22A1 SSPOP

6.98e-081848672b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

THBS2 MOXD1 CILP2 FBN2 COL16A1 TNN DKK3

1.15e-07198867c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

THBS2 MOXD1 COL16A1 TNN ASTN1 ADAMTS8 DKK3

1.15e-07198867300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

THBS2 MOXD1 CILP2 FBN2 COL16A1 TNN DKK3

1.15e-071988673e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

THBS2 MOXD1 CILP2 FBN2 COL16A1 TNN DKK3

1.15e-07198867196257c4420ac801ed9fbb444f11718adb7560ae
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

THBS2 CILP2 COL16A1 TNN LNX1 LTBP4 DKK3

1.15e-071988679f9dcf23ffb333105263132d87b90095642294cf
ToppCell(5)_Fibroblast-B_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ITGA11 THBS2 MOXD1 CILP2 COL16A1 TNN DKK3

1.23e-072008679bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 TAF7L MED12L PCDHB3 LRP4 DKK3

5.07e-0715286672499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCelldroplet-Fat-Scat-21m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 MOXD1 FCGBP FBN2 CNMD LTBP4

8.19e-071658663f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 DENND4A TRPM3 PITPNM3 TMPRSS4 FANCA

1.12e-06174866f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FRAS1 COL16A1 PCDHB13 LRP4 ADAMTS18 COL22A1

1.27e-06178866e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CILP2 FBN2 CNMD ANKAR PCDHB16 FANCA

1.45e-0618286603a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

1.65e-061868665473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

1.98e-061928664e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4 DKK3

2.10e-06194866e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

2.16e-061958662b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4 DKK3

2.16e-06195866edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ITGA11 THBS2 COL16A1 TNN LNX1 DKK3

2.16e-0619586678978d85273e5463a7f43e4c121e647fa6aba42b
ToppCellASK428-Mesenchymal-Fibroblast|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

2.16e-06195866c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCellCOPD-Stromal-Myofibroblast|COPD / Disease state, Lineage and Cell class

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

2.23e-06196866af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

2.23e-0619686642e9828222a9663525d571633e8a454c30bfa7f8
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

THBS2 FBN2 COL16A1 SEMA5B LTBP4 DKK3

2.23e-06196866eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4 DKK3

2.29e-06197866ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4 DKK3

2.29e-0619786637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS2 CILP2 FBN2 COL16A1 TNN DKK3

2.29e-061978663fe665c0277d091290b63f0dd24c0c6536a45309
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 CILP2 FBN2 COL16A1 COL22A1 DKK3

2.36e-06198866524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCellBiopsy_Control_(H.)-Mesenchymal-Myofibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

2.43e-061998667a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

2.43e-061998660019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

2.50e-06200866e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 FBN2 COL16A1 TNN CNMD DKK3

2.50e-06200866be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCell15-Airway|15 / Age, Tissue, Lineage and Cell class

THBS2 FBN2 COL16A1 PPP1R15A LTBP4 DKK3

2.50e-06200866ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 FBN2 COL16A1 TNN CNMD DKK3

2.50e-062008668e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBS2 MOXD1 IL16 COL16A1 ADAMTS8 DKK3

2.50e-06200866cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte|GW12 / Sample Type, Dataset, Time_group, and Cell type.

MOXD1 TRPM3 CNMD NELFB EFCAB2 PCDHB3

2.50e-06200866b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP2 FBN2 COL16A1 TNN CNMD DKK3

2.50e-06200866c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THBS2 MOXD1 IL16 COL16A1 ADAMTS8 DKK3

2.50e-06200866311fab076f2ceb258e3970eb21e39344b894042a
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FBN2 LRP2 ASTN1 COL22A1

1.47e-05160865c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FBN2 LRP2 ASTN1 COL22A1

1.47e-0516086525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A TNN MED12L SMOX FANCA

1.66e-051648658e6dbddacd56a07769163813e3ebfad13302bb62
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 TRPM3 TAF7L ZNF641 ZNF543

1.71e-05165865e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 TRPM3 TAF7L ZNF641 ZNF543

1.71e-05165865b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 TRPM3 TAF7L ZNF641 ZNF543

1.71e-05165865d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD PCDHB14 PITPNM3 LTBR MEFV

1.76e-05166865e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCellBasal_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL16A1 LRP4 TMPRSS4 LTBP4 DKK3

1.76e-0516686523c04d1fba0c1733ccd0e4378fae2edde4fd0a7b
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD PCDHB14 PITPNM3 LTBR MEFV

1.76e-051668653ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD PCDHB14 PITPNM3 LTBR MEFV

1.76e-05166865f751cbd01d4978ded7755874ab60504f6291afd7
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

MALRD1 PCDHB14 TMPRSS4 COL22A1 DKK3

1.97e-05170865776d4224a682b6c648041827efd69794f88906f0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CILP2 FCGBP FBN2 MED12L TMPRSS4

2.21e-0517486546bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

ITGA11 MOXD1 COL16A1 PCDHB14 DKK3

2.40e-05177865cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

ITGA11 MOXD1 COL16A1 PCDHB14 DKK3

2.40e-05177865db222faaecbe5600da39277243c4e7e764eb63c9
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS2 IL16 KMT2B LRP4 MGA

2.46e-05178865c87945146b2734141f07b39d268e0d8086ee0364
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 MOXD1 PCDHB11 LTBP4 DKK3

2.60e-05180865ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 COL16A1 TNN LTBP4 DKK3

2.67e-051818659c157de9d3403e092c907599f2a2c16db5b21131
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4

2.67e-05181865c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 COL16A1 LRP4 LTBP4 DKK3

2.67e-05181865b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

ITGA11 THBS2 FBN2 COL16A1 DKK3

2.67e-05181865bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 COL16A1 TNN LTBP4 DKK3

2.67e-05181865eea943fdcbef0bbaa8578f3296923e874893b405
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4

2.67e-05181865c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THBS2 MOXD1 CILP2 CNMD PCDHB3

2.74e-05182865bb7de0c93d8f59f13c990e425139b9348ca8027e
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular-Chondrocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THBS2 MOXD1 CILP2 CNMD PCDHB3

2.74e-05182865507f095af4dff60f2c2b64d750477154084c3595
ToppCellcellseq-Mesenchymal-Chondrocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THBS2 MOXD1 CILP2 CNMD PCDHB3

2.74e-0518286588bd17c07bd8443a0ede4e9dc7bc9d1230b42211
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 MOXD1 COL16A1 LTBP4 DKK3

2.74e-05182865b7d532feb73167e05475855061b35a209583f44c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 MOXD1 COL16A1 LTBP4 DKK3

2.74e-05182865af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCellBasal|World / shred by cell class for mouse tongue

MOXD1 COL16A1 IRF2BPL LTBP4 DKK3

2.81e-05183865c6729a207526ff4aa48176207b9353176f631fea
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOXD1 CILP2 TRPM3 ADAMTS8 LTBP4

2.81e-051838652beb5414958d38a5341870d55229f3b1707e76bf
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 COL16A1 TNN LTBP4 DKK3

2.81e-05183865bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

ITGA11 THBS2 MOXD1 CILP2 COL16A1

2.96e-05185865e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA11 THBS2 MOXD1 CILP2 COL16A1

2.96e-0518586587c416d14ca6255bee39b16e7571553e36ee3069
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 CNMD ALAS1 MEFV FANCA

2.96e-0518586553854a9ec87c24c360541c83d86d8fafb303ad58
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 CNMD ALAS1 MEFV FANCA

2.96e-05185865a61fc7a3700a1efcf640bef7680c0443ee148a46
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND4A RNF213 ALAS1 PPP1R15A TP53BP2

2.96e-05185865a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCell15-Distal-Immune-Hematopoietic,_T_Cells|Distal / Age, Tissue, Lineage and Cell class

EYS IL16 ADGRG3 DEF6 ADGRE1

2.96e-05185865481e3d3b63f2e5b4783088523c3cf70a461aed27
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 MOXD1 FBN2 COL16A1 LTBP4

2.96e-05185865785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 MOXD1 FBN2 COL16A1 LTBP4

2.96e-0518586597a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS2 CILP2 COL16A1 TNN CRB2

3.04e-051868654e983de6d2515082f9e555f4f949cec84281c140
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 MOXD1 FBN2 COL16A1 LTBP4

3.04e-0518686594d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 MOXD1 IL16 COL16A1 LTBP4

3.20e-05188865ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell5'-Adult-SmallIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP MALRD1 CABP7 COL16A1 TMPRSS4

3.20e-0518886591fa9cc29cbc88d3c29590ecee5c8ce858ac0aa7
ToppCell5'-Adult-SmallIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP MALRD1 CABP7 COL16A1 TMPRSS4

3.28e-051898656f4f2911fcbf3b43718b6183dbd9c970d4c19607
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 MOXD1 COL16A1 LTBP4 DKK3

3.28e-0518986571397e993a77d70b2eeede240bdfc7660b558987
ToppCellfacs-Skin-nan-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 FCGBP COL16A1 TAF7L LRP4

3.28e-051898656c71e81373cb7822de23c193a6350b6df9f567bc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 MOXD1 COL16A1 LTBP4 DKK3

3.28e-051898654eea4759520c312bd17a681034d8074e47093d2b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MOXD1 COL16A1 ADAMTS8 LTBP4 DKK3

3.28e-05189865a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4

3.28e-05189865e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THBD MOXD1 ADAMTS18 PPP1R15A LTBP4

3.36e-05190865e1b721bb74561fe51c53328a0394c9954e489049
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 MOXD1 IL16 COL16A1 LTBP4

3.36e-05190865efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCelldroplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 MOXD1 FCGBP COL16A1 LTBP4

3.36e-05190865c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS2 MOXD1 ADAMTS8 LTBP4 DKK3

3.36e-05190865d60395739458d7f47a3350ade751fe3819500320
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 MOXD1 COL16A1 LTBP4 DKK3

3.45e-05191865a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS2 MOXD1 COL16A1 ADAMTS8 LTBP4

3.45e-05191865b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

THBS2 MOXD1 ADAMTS8 LTBP4 DKK3

3.45e-05191865f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4

3.45e-0519186539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 MOXD1 COL16A1 LTBP4 DKK3

3.45e-051918650fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MOXD1 ADAMTS18 ALAS1 PPP1R15A LTBP4

3.45e-05191865d162917816dd2e4767c97447c1cddae9397713ab
ToppCellASK440-Mesenchymal-Fibroblast|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

THBS2 MOXD1 ADAMTS8 LTBP4 DKK3

3.45e-05191865387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FRAS1 MOXD1 IL16 ADAMTS8 DKK3

3.45e-051918656688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 THBS2 MOXD1 COL16A1 LTBP4

3.45e-05191865ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
Diseaseresponse to platinum based chemotherapy, cytotoxicity measurement

FRAS1 EYS

7.40e-055812EFO_0004647, EFO_0006952
Diseaseautosomal dominant polycystic kidney disease (biomarker_via_orthology)

SLC34A1 LRP2

1.55e-047812DOID:898 (biomarker_via_orthology)
Diseasecortical thickness

VPS13D FBN2 MALRD1 KMT2B PCDHB11 LRP4 ADAMTS18 ADAMTS8 LNX1 PCDHB16 CRB2

2.26e-0411138111EFO_0004840
Diseaseend stage renal disease (biomarker_via_orthology)

SLC34A1 LRP2 BECN1

2.96e-0447813DOID:783 (biomarker_via_orthology)
Diseaselymphocyte count

FRAS1 IL16 CILP2 ZBTB38 EGF ZAN MARCHF8 DEF6 MED12L LTBR ADGRE1 SMOX

6.29e-0414648112EFO_0004587
Diseaseischemia (biomarker_via_orthology)

THBD BECN1

1.11e-0318812DOID:326 (biomarker_via_orthology)
Diseaseovulation

MCM8 FANCA

1.23e-0319812GO_0030728
Diseaseanti-Mullerian hormone measurement

MCM8 TNN

1.37e-0320812EFO_0004769
Diseasecorneal resistance factor

ZBTB38 FBN2 TRPM3 ADAMTS18 ADAMTS8 LNX1

1.52e-03451816EFO_0010067
Diseasecentral corneal thickness

ZBTB38 FBN2 ADAMTS18 ADAMTS8 LNX1

1.63e-03309815EFO_0005213
Diseasehemoglobin measurement, mean corpuscular hemoglobin

DENND4A MARCHF8

1.66e-0322812EFO_0004509, EFO_0004527
Diseasevital capacity

THBS2 ZBTB38 SLC34A1 LRP2 ADAMTS18 ADAMTS8 SMOX LNX1 LTBP4 DKK3

2.02e-0312368110EFO_0004312
Diseaseankylosing spondylitis

MALRD1 LTBR MEFV

2.03e-0391813EFO_0003898
DiseaseUterine leiomyoma

ITGA11 MCM8 LNX1

2.03e-0391813HP_0000131
Diseasebreast cancer (implicated_via_orthology)

BECN2 BECN1

2.14e-0325812DOID:1612 (implicated_via_orthology)
Diseaseretinitis pigmentosa (implicated_via_orthology)

EYS CRB2

2.50e-0327812DOID:10584 (implicated_via_orthology)
Diseaseobsessive-compulsive disorder

MALRD1 TNN ZNF543

2.66e-03100813EFO_0004242

Protein segments in the cluster

PeptideGeneStartEntry
HIYCDPELVLEEGCC

COL16A1

226

Q07092
LCSEGSCLPEEEVER

ADAMTS8

506

Q9UP79
LLDECGLELGEDTPH

GSDMD

441

P57764
VLEAPALHCEVCELH

DGKQ

141

P52824
EVRPEGTVCCCDHLT

ADGRG3

236

Q86Y34
VVDLCKEPGESDCHL

TP53BP2

31

Q13625
RLLDPCEHQCDPETG

ASTN1

466

O14525
IDGVCELVGCDHELG

ADAMTS18

716

Q8TE60
LTDEDVCHELEGPIS

DENND4A

1371

Q7Z401
LLDCECTGEEVHTGD

RAD54B

826

Q9Y620
RCEEELHGLIQVPCS

RDM1

241

Q8NG50
LLVCDEPEVHSRCAV

ANKAR

791

Q7Z5J8
CLGRLDSLPEHEDSE

RB1CC1

216

Q8TDY2
LDREDLCGHTEPCVL

PCDHB13

91

Q9Y5F0
SLGCCPTEGELHDLI

EFCAB2

181

Q5VUJ9
ARDEELIHLDGKCCP

FRAS1

326

Q86XX4
VGEHCLKEPERLCTD

MED12L

1256

Q86YW9
DECLSEPCLHDGVCI

EYS

1006

Q5T1H1
IECELVHDLVDSCVP

MCM8

311

Q9UJA3
HLDEECLPEEGCATV

MGA

2031

Q8IWI9
AGLHCEPETLLSVEE

NUDT18

96

Q6ZVK8
VCPLEELCDVAHEFG

ALAS1

391

P13196
EEDVDECLSDPCLHG

CRB2

356

Q5IJ48
DVDHPLCEECTDTLL

BECN1

131

Q14457
GPLCCTICHERLEDT

IRF2BPL

711

Q9H1B7
ECGACLRVLEGHEEL

FBXW11

431

Q9UKB1
CGDEIVEISDSPVHC

IL16

401

Q14005
HDLDVGEICTVDPCH

NELFB

246

Q8WX92
YPEEVDDDLICHICL

LNX1

31

Q8TBB1
RICHCEGDDESPLIT

MARCHF8

81

Q5T0T0
HRVLPEGATCDEEED

KMT2B

2531

Q9UMN6
DCGDGSDEELHLCLD

LRP2

3866

P98164
FCEDHDEPICLICSL

MEFV

386

O15553
CNEDEHCVPDLVLDA

ITGA11

781

Q9UKX5
RICHCEGDEESPLIT

MARCHF1

81

Q8TCQ1
DREELCGSIEPCVLH

PCDHB11

91

Q9Y5F2
ALAEHTCPCGEVLER

SLC34A1

56

Q06495
DREELCGPTEPCILH

PCDHB16

91

Q9NRJ7
LNAERELCHPDTDLC

MALRD1

241

Q5VYJ5
ELCHPDTDLCRFDAT

MALRD1

246

Q5VYJ5
DRDELCGSTEPCVLH

PCDHB14

91

Q9Y5E9
AVVDHPLCEECTDSL

BECN2

111

A8MW95
HLGTAEECPVDVETC

CABP7

161

Q86V35
DGIHCLDIDECQLGE

EGF

906

P01133
LDIDECQLGEHSCGE

EGF

911

P01133
AACGPHEECRLEDGV

FCGBP

4831

Q9Y6R7
SHVAELLADRGDCDP

FANCA

1416

O15360
DSRHAELETCCDIPS

COL22A1

426

Q8NFW1
RCPDCGSTELVEDSH

BRF2

6

Q9HAW0
PLDAHCCVEVLPDRD

DEF6

261

Q9H4E7
GPRAAECLDVDECHR

LTBP4

621

Q8N2S1
DTRICEDIDECFAHP

FBN2

1686

P35556
GRRSHECIIDEDCGP

DKK3

141

Q9UBP4
VEGELCHDPASRLLD

DKK3

236

Q9UBP4
PSHRECCPAVEEEDD

PPP1R15A

181

O75807
DREELCGPTEPCILH

PCDHB3

91

Q9Y5E6
LDREDLCGHTEPCVL

PCDHB8

91

Q9UN66
LVCTADGDIHLSPEE

TAF7L

181

Q5H9L4
HRCEDVDDCILEPSP

THBD

321

P07204
LCDGHPDCLDAADEE

SSPOP

1471

A2VEC9
CDFDLRPCHETTVDI

MITD1

226

Q8WV92
HPLEESRDCLAFCTE

SCYL2

106

Q6P3W7
PGCTDIDDALHCREL

DIS3

481

Q9Y2L1
EACAHLRDPECLLVA

PDXP

161

Q96GD0
EDVDECADPRACPEH

ADGRE1

171

Q14246
LDTCECPDHILLGSV

CILP2

201

Q8IUL8
TFDPRLDHEGICCIE

CNMD

271

O75829
AFLPDCLDLETLGHC

RNF213

1791

Q63HN8
LGEPAEELCEEFLAH

VPS51

261

Q9UID3
EGHCTLECLEEALEA

MOXD1

361

Q6UVY6
HCEEGREGPACERLA

TNN

156

Q9UQP3
VDCPHEEGELDSCPT

TRPV1

61

Q8NER1
GLGDKVEDLTCCHPE

TRPM3

1596

Q9HCF6
VEDLTCCHPEREAEL

TRPM3

1601

Q9HCF6
ECEDCELIPADHVIV

SMOX

316

Q9NWM0
LDCPLGEDEEHCVKS

TMPRSS4

81

Q9NRS4
EDICLGLHTEEALCA

SEMA5B

946

Q9P283
CVDDTLIVLAEEHGC

TBCK

221

Q8TEA7
EIHEDSEEGCPQRSC

PITPNM3

111

Q9BZ71
HCELLSDCPPGTEAE

LTBR

141

P36941
CDSHGPVTDALIREE

ZNF543

181

Q08ER8
LCLERTDVCHEAEPV

ZBTB38

201

Q8NAP3
THCEDLDECALVPDI

THBS2

586

P35442
LIHTGEKPFECDICD

ZNF740

121

Q8NDX6
CSLCHVLPDLKEEDG

TRIM28

666

Q13263
EHCVLDLCSAQDPRE

ZAN

2571

Q9Y493
PEDHVCLLDCVVVDL

VPS13D

2146

Q5THJ4
DCGDCHPLELVVRDS

ZBTB8B

196

Q8NAP8
GPLEHLCCDLEEEPQ

ZNF641

56

Q96N77
DCGDHSDEDGCILPT

LRP4

56

O75096