Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	polysaccharide binding	CLEC18A CLEC18B CLEC18C	1.45e-04	31	66	3	GO:0030247
GeneOntologyMolecularFunction	histone H3K9 monomethyltransferase activity	SETDB1 EHMT2	2.97e-04	8	66	2	GO:0140948
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETDB1 SETD2 EHMT2	4.15e-04	44	66	3	GO:0140938
GeneOntologyMolecularFunction	histone H3K9me2 methyltransferase activity	SETDB1 EHMT2	4.76e-04	10	66	2	GO:0140947
GeneOntologyMolecularFunction	histone H3K9 methyltransferase activity	SETDB1 EHMT2	8.20e-04	13	66	2	GO:0046974
GeneOntologyCellularComponent	extracellular matrix	TGFB1I1 ADAMTS12 HMCN1 MEGF6 LAMB1 MUC5B LTBP1 SSPOP OTOG	2.09e-04	656	66	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	TGFB1I1 ADAMTS12 HMCN1 MEGF6 LAMB1 MUC5B LTBP1 SSPOP OTOG	2.14e-04	658	66	9	GO:0030312
Domain	EGF_3	CLEC18A THBD CELSR1 CLEC18B HMCN1 MEGF6 CLEC18C LTBP1 C6 NRG3 SSPOP OTOG	3.21e-11	235	66	12	PS50026
Domain	EGF-like_dom	CLEC18A THBD CELSR1 CLEC18B HMCN1 MEGF6 CLEC18C LAMB1 LTBP1 C6 NRG3 OTOG	6.30e-11	249	66	12	IPR000742
Domain	EGF_1	CLEC18A THBD CELSR1 CLEC18B HMCN1 MEGF6 CLEC18C LAMB1 LTBP1 C6 NRG3 SSPOP	8.30e-11	255	66	12	PS00022
Domain	EGF_2	CLEC18A THBD CELSR1 CLEC18B HMCN1 MEGF6 CLEC18C LAMB1 LTBP1 C6 NRG3 SSPOP	1.29e-10	265	66	12	PS01186
Domain	-	CLEC18A CLEC18B CLEC18C PI15 CRISPLD1	1.38e-09	15	66	5	3.40.33.10
Domain	CAP	CLEC18A CLEC18B CLEC18C PI15 CRISPLD1	1.38e-09	15	66	5	PF00188
Domain	CAP_domain	CLEC18A CLEC18B CLEC18C PI15 CRISPLD1	1.38e-09	15	66	5	IPR014044
Domain	SCP	CLEC18A CLEC18B CLEC18C PI15 CRISPLD1	1.38e-09	15	66	5	SM00198
Domain	Allrgn_V5/Tpx1	CLEC18A CLEC18B CLEC18C PI15 CRISPLD1	1.38e-09	15	66	5	IPR001283
Domain	EGF-like_CS	CLEC18A THBD CELSR1 CLEC18B HMCN1 MEGF6 CLEC18C LAMB1 LTBP1 C6 NRG3	1.75e-09	261	66	11	IPR013032
Domain	EGF	CLEC18A THBD CELSR1 CLEC18B HMCN1 MEGF6 CLEC18C LAMB1 LTBP1 NRG3	9.35e-09	235	66	10	SM00181
Domain	TSP_1	ADAMTS12 HMCN1 ADGRB1 C6 SSPOP	2.83e-06	63	66	5	PF00090
Domain	TSP1	ADAMTS12 HMCN1 ADGRB1 C6 SSPOP	3.31e-06	65	66	5	SM00209
Domain	TSP1_rpt	ADAMTS12 HMCN1 ADGRB1 C6 SSPOP	3.31e-06	65	66	5	IPR000884
Domain	TSP1	ADAMTS12 HMCN1 ADGRB1 C6 SSPOP	3.31e-06	65	66	5	PS50092
Domain	EGF	THBD CELSR1 HMCN1 MEGF6 LTBP1 NRG3	5.46e-06	126	66	6	PF00008
Domain	TIL	MUC5B SSPOP OTOG	9.06e-06	12	66	3	PF01826
Domain	C8	MUC5B SSPOP OTOG	9.06e-06	12	66	3	PF08742
Domain	Unchr_dom_Cys-rich	MUC5B SSPOP OTOG	1.18e-05	13	66	3	IPR014853
Domain	C8	MUC5B SSPOP OTOG	1.18e-05	13	66	3	SM00832
Domain	TIL_dom	MUC5B SSPOP OTOG	1.49e-05	14	66	3	IPR002919
Domain	Growth_fac_rcpt_	THBD CELSR1 HMCN1 MEGF6 LAMB1 LTBP1	1.85e-05	156	66	6	IPR009030
Domain	Post-SET_dom	SETDB1 SETD2 EHMT2	2.28e-05	16	66	3	IPR003616
Domain	VWD	MUC5B SSPOP OTOG	2.28e-05	16	66	3	SM00216
Domain	PostSET	SETDB1 SETD2 EHMT2	2.28e-05	16	66	3	SM00508
Domain	VWF_type-D	MUC5B SSPOP OTOG	2.28e-05	16	66	3	IPR001846
Domain	VWFD	MUC5B SSPOP OTOG	2.28e-05	16	66	3	PS51233
Domain	POST_SET	SETDB1 SETD2 EHMT2	2.28e-05	16	66	3	PS50868
Domain	VWD	MUC5B SSPOP OTOG	2.28e-05	16	66	3	PF00094
Domain	ASX_HYDROXYL	THBD CELSR1 HMCN1 MEGF6 LTBP1	2.74e-05	100	66	5	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	THBD CELSR1 HMCN1 MEGF6 LTBP1	3.63e-05	106	66	5	IPR000152
Domain	VWC_out	MUC5B SSPOP OTOG	3.92e-05	19	66	3	SM00215
Domain	EGF_CA	THBD CELSR1 HMCN1 MEGF6 LTBP1	7.12e-05	122	66	5	SM00179
Domain	EGF-like_Ca-bd_dom	THBD CELSR1 HMCN1 MEGF6 LTBP1	7.69e-05	124	66	5	IPR001881
Domain	Cys_knot_C	MUC5B SSPOP OTOG	9.17e-05	25	66	3	IPR006207
Domain	CTCK_2	MUC5B SSPOP OTOG	9.17e-05	25	66	3	PS01225
Domain	cEGF	THBD HMCN1 LTBP1	1.03e-04	26	66	3	IPR026823
Domain	cEGF	THBD HMCN1 LTBP1	1.03e-04	26	66	3	PF12662
Domain	Lectin_C	CLEC18A THBD CLEC18B CLEC18C	2.22e-04	84	66	4	PF00059
Domain	CLECT	CLEC18A THBD CLEC18B CLEC18C	2.22e-04	84	66	4	SM00034
Domain	C_TYPE_LECTIN_2	CLEC18A THBD CLEC18B CLEC18C	2.32e-04	85	66	4	PS50041
Domain	C-type_lectin-like	CLEC18A THBD CLEC18B CLEC18C	2.43e-04	86	66	4	IPR001304
Domain	EGF_CA	THBD HMCN1 MEGF6 LTBP1	2.43e-04	86	66	4	PF07645
Domain	Laminin_EGF	CELSR1 MEGF6 LAMB1	2.54e-04	35	66	3	PF00053
Domain	EGF_Lam	CELSR1 MEGF6 LAMB1	2.54e-04	35	66	3	SM00180
Domain	PreSET	SETDB1 EHMT2	2.55e-04	7	66	2	SM00468
Domain	Pre-SET	SETDB1 EHMT2	2.55e-04	7	66	2	PF05033
Domain	Pre-SET_dom	SETDB1 EHMT2	2.55e-04	7	66	2	IPR007728
Domain	PRE_SET	SETDB1 EHMT2	2.55e-04	7	66	2	PS50867
Domain	Laminin_EGF	CELSR1 MEGF6 LAMB1	3.25e-04	38	66	3	IPR002049
Domain	EGF_Ca-bd_CS	THBD HMCN1 MEGF6 LTBP1	3.85e-04	97	66	4	IPR018097
Domain	-	CLEC18A THBD CLEC18B CLEC18C	3.85e-04	97	66	4	3.10.100.10
Domain	SET	SETDB1 SETD2 EHMT2	4.08e-04	41	66	3	PF00856
Domain	C-type_lectin-like/link	CLEC18A THBD CLEC18B CLEC18C	4.16e-04	99	66	4	IPR016186
Domain	EGF_CA	THBD HMCN1 MEGF6 LTBP1	4.16e-04	99	66	4	PS01187
Domain	VWF_dom	MUC5B SSPOP OTOG	4.38e-04	42	66	3	IPR001007
Domain	C-type_lectin_CS	CLEC18A CLEC18B CLEC18C	4.70e-04	43	66	3	IPR018378
Domain	Allrgn_V5/Tpx1_CS	PI15 CRISPLD1	5.43e-04	10	66	2	IPR018244
Domain	CTDL_fold	CLEC18A THBD CLEC18B CLEC18C	5.59e-04	107	66	4	IPR016187
Domain	SET	SETDB1 SETD2 EHMT2	5.74e-04	46	66	3	SM00317
Domain	GAIN_dom_N	CELSR1 ADGRB1	6.63e-04	11	66	2	IPR032471
Domain	CRISP_1	PI15 CRISPLD1	6.63e-04	11	66	2	PS01009
Domain	GAIN	CELSR1 ADGRB1	6.63e-04	11	66	2	PF16489
Domain	CRISP_2	PI15 CRISPLD1	6.63e-04	11	66	2	PS01010
Domain	SET_dom	SETDB1 SETD2 EHMT2	7.34e-04	50	66	3	IPR001214
Domain	SET	SETDB1 SETD2 EHMT2	7.34e-04	50	66	3	PS50280
Domain	EMI	MEGF6 SSPOP	1.62e-03	17	66	2	PS51041
Domain	USP_CS	USP31 USP43 USP27X	1.65e-03	66	66	3	IPR018200
Domain	CTCK_1	MUC5B SSPOP	1.81e-03	18	66	2	PS01185
Domain	USP_1	USP31 USP43 USP27X	1.95e-03	70	66	3	PS00972
Domain	UCH	USP31 USP43 USP27X	2.03e-03	71	66	3	PF00443
Domain	USP_2	USP31 USP43 USP27X	2.03e-03	71	66	3	PS00973
Domain	USP_3	USP31 USP43 USP27X	2.11e-03	72	66	3	PS50235
Domain	USP_dom	USP31 USP43 USP27X	2.11e-03	72	66	3	IPR028889
Domain	Peptidase_C19_UCH	USP31 USP43 USP27X	2.11e-03	72	66	3	IPR001394
Domain	CT	MUC5B OTOG	2.71e-03	22	66	2	SM00041
Domain	C_TYPE_LECTIN_1	CLEC18A CLEC18B CLEC18C	2.85e-03	80	66	3	PS00615
Domain	HormR	CELSR1 ADGRB1	3.50e-03	25	66	2	SM00008
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 GALNT10 MUC5B POMT1 SSPOP	1.71e-05	109	42	5	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS12 GALNT10 MUC5B POMT1 SSPOP	1.86e-05	111	42	5	M27416
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS12 MUC5B POMT1 SSPOP	4.83e-05	68	42	4	M27303
Pathway	KEGG_LYSINE_DEGRADATION	SETDB1 SETD2 EHMT2	2.99e-04	44	42	3	M13720
Pathway	REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES	SETDB1 SETD2 EHMT2	3.41e-04	46	42	3	MM14933
Pubmed	Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.	CLEC18A CLEC18B CLEC18C	6.53e-09	3	66	3	26170455
Pubmed	The C-type lectin-like domain superfamily.	CLEC18A CLEC18B CLEC18C	6.53e-09	3	66	3	16336259
Pubmed	Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.	CLEC18A CLEC18B CLEC18C	6.53e-09	3	66	3	33603190
Pubmed	The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.	CLEC18A CLEC18B CLEC18C	2.61e-08	4	66	3	16709836
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS12 HMCN1 ADGRB1 C6 SSPOP	3.28e-07	75	66	5	20637190
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	ADAMTS12 CLEC18A CLEC18B PROM2 CLEC18C ATP13A5 SHISA2 CRISPLD1	2.59e-06	460	66	8	20562862
Pubmed	Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity.	FAM13A LEPR	3.55e-06	2	66	2	30301961
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	GALNT10 FAM13A MEGF6 PROM2 POMT1 PFKFB4 NRG3 SSPOP CASZ1 VPS13B MOCOS BICD1 ZC3HAV1	3.79e-06	1489	66	13	28611215
Pubmed	Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression.	THBD LEPR	1.06e-05	3	66	2	36030260
Pubmed	Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1.	EHMT2 LEPR	1.06e-05	3	66	2	29101051
Pubmed	Immunohistochemistry for histone h3 lysine 9 methyltransferase and demethylase proteins in human melanomas.	SETDB1 EHMT2	1.06e-05	3	66	2	24658378
Pubmed	MUC5B mucin production is upregulated by fibronectin and laminin in human lung epithelial cells via the integrin and ERK dependent pathway.	LAMB1 MUC5B	1.06e-05	3	66	2	26057585
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B LEPR	1.06e-05	3	66	2	20422702
Pubmed	Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes.	PHLPP1 LEPR	1.06e-05	3	66	2	34348155
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	ADAMTS12 CLEC18A CLEC18B PROM2 SUSD3 ATP13A5 WDR82 SHISA2 TNFRSF21 CRISPLD1	1.59e-05	985	66	10	12975309
Pubmed	Hemicentin 1 influences podocyte dynamic changes in glomerular diseases.	HMCN1 LEPR	2.12e-05	4	66	2	29488390
Pubmed	Expression of the histone lysine methyltransferases SETD1B, SETDB1, SETD2, and CFP1 exhibits significant changes in the oocytes and granulosa cells of aged mouse ovaries.	SETDB1 SETD2	2.12e-05	4	66	2	35445296
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	HMCN1 MEGF6 LAMB1 LTBP1 SSPOP	2.12e-05	175	66	5	28071719
Pubmed	EHMT2 and SETDB1 protect the maternal pronucleus from 5mC oxidation.	SETDB1 EHMT2	3.53e-05	5	66	2	31088968
Pubmed	A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.	SETDB1 EHMT2	3.53e-05	5	66	2	19010785
Pubmed	Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.	SETDB1 EHMT2	3.53e-05	5	66	2	18498648
Pubmed	Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.	CLEC18A CLEC18B CLEC18C	4.84e-05	37	66	3	22432025
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	TGFB1I1 SETDB1 UBR4 WDR82 PFKFB4 TNFRSF21 MEX3B LEPR ZNF71 NCOA5	4.87e-05	1124	66	10	21900206
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZNF862 PHLPP1 SSPOP VPS13B	4.89e-05	105	66	4	9628581
Pubmed	Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.	SETD2 EHMT2	5.29e-05	6	66	2	24019522
Pubmed	SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response.	SETDB1 EHMT2	5.29e-05	6	66	2	23034801
Pubmed	Dynamics of Setdb1 expression in early mouse development.	SETDB1 EHMT2	7.40e-05	7	66	2	22504302
Pubmed	LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity.	ACSL4 EHMT2	7.40e-05	7	66	2	37166352
Pubmed	PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia.	SETDB1 EHMT2	7.40e-05	7	66	2	29774127
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	TGFB1I1 MEGF6 ZNF592 UBR4 ADGRB1 C6 STOX1 SSPOP	7.54e-05	736	66	8	29676528
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	MEGF6 EHMT2 LAMB1 LTBP1	7.71e-05	118	66	4	21078624
Pubmed	Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.	AP5Z1 UBR4	9.86e-05	8	66	2	37871017
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	TGFB1I1 SETDB1 SETD2 MEGF6 LAMB1 LTBP1 SSPOP	1.54e-04	608	66	7	16713569
Pubmed	CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.	SETDB1 EHMT2	1.58e-04	10	66	2	19061646
Pubmed	Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development.	SETDB1 EHMT2	1.58e-04	10	66	2	23333759
Pubmed	Esco2 is a novel corepressor that associates with various chromatin modifying enzymes.	SETDB1 EHMT2	1.58e-04	10	66	2	18501190
Pubmed	Cohesion establishment factor, Eco1 represses transcription via association with histone demethylase, LSD1.	SETDB1 EHMT2	1.58e-04	10	66	2	20331966
Pubmed	New nomenclature for chromatin-modifying enzymes.	SETDB1 SETD2 EHMT2	1.77e-04	57	66	3	18022353
Pubmed	CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592.	ZNF592 MEX3B	1.93e-04	11	66	2	20531441
Pubmed	Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency.	SETDB1 EHMT2	1.93e-04	11	66	2	23748610
Pubmed	A protein interaction landscape of breast cancer.	ACSL4 UBR4 MRPS5 MUC5B LTBP1 PFKFB4 ZC3HAV1	1.99e-04	634	66	7	34591612
Pubmed	Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia.	SETDB1 EHMT2	2.31e-04	12	66	2	21402781
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	HMCN1 LAMB1 SSPOP	2.50e-04	64	66	3	22261194
Pubmed	Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.	SETDB1 EHMT2	3.67e-04	15	66	2	35907431
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	CELSR1 SSPOP	3.67e-04	15	66	2	20473291
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP31 USP43 USP27X	5.01e-04	81	66	3	12838346
Pubmed	The short 3'-end region of complementary DNAs as PCR-based polymorphic markers for an expression map of the mouse genome.	HOXB7 LAMB1	5.32e-04	18	66	2	8486351
Pubmed	Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.	TGFB1I1 THBD LAMB1 LTBP1	5.37e-04	196	66	4	19334288
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	TGFB1I1 ACSL4 SETDB1 MIS18BP1 TRIM17 ADGRB1 MRPS5 LTBP1 PFKFB4	5.45e-04	1242	66	9	30973865
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TGFB1I1 SETD2 FAM13A MEGF6 LTBP1 BICD1	6.80e-04	560	66	6	21653829
Pubmed	UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.	UBR4 NCOA5	7.28e-04	21	66	2	37422473
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	THBD PROM2 USP43 SHISA2 VPS13B BICD1	7.39e-04	569	66	6	30639242
Pubmed	Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.	SETDB1 EHMT2	7.99e-04	22	66	2	28963472
Pubmed	Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.	USP31 USP43	8.75e-04	23	66	2	14715245
Pubmed	OTUB1 modulates c-IAP1 stability to regulate signalling pathways.	UBR4 WDR82	9.53e-04	24	66	2	23524849
Pubmed	Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.	HOXB7 LAMB1	1.12e-03	26	66	2	9226367
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CELSR1 PSME4 MEGF6 ZNF592 PROM2 UBR4 TNFRSF21 CASZ1	1.14e-03	1105	66	8	35748872
Pubmed	Deep sequencing and proteomic analysis of the microRNA-induced silencing complex in human red blood cells.	UBR4 ZC3HAV1	1.39e-03	29	66	2	25681748
Pubmed	Identification of cathepsin K as a novel marker of adiposity in white adipose tissue.	SETDB1 LEPR	1.39e-03	29	66	2	12652657
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	CELSR1 ADGRB1	1.80e-03	33	66	2	25713288
Pubmed	A common variant in DRD3 receptor is associated with autism spectrum disorder.	LAMB1 CASP9 LEPR	1.88e-03	128	66	3	19058789
Cytoband	8q21.11	PI15 CRISPLD1	7.74e-04	28	67	2	8q21.11
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	CLEC18A PDXDC2P CLEC18C	2.47e-03	183	67	3	chr16q22
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETDB1 SETD2 EHMT2	1.33e-04	34	53	3	487
GeneFamily	C-type lectin domain family	CLEC18A CLEC18B CLEC18C	3.52e-04	47	53	3	494
GeneFamily	Ubiquitin specific peptidases	USP31 USP43 USP27X	5.91e-04	56	53	3	366
Coexpression	NABA_MATRISOME	ADAMTS12 CLEC18A CLEC18B HMCN1 MEGF6 CLEC18C LAMB1 MUC5B LTBP1 NRG3 SSPOP CRISPLD1 OTOG	1.38e-06	1008	67	13	MM17056
Coexpression	NABA_MATRISOME	ADAMTS12 CLEC18A CLEC18B HMCN1 MEGF6 CLEC18C LAMB1 MUC5B LTBP1 NRG3 SSPOP CRISPLD1 OTOG	1.67e-06	1026	67	13	M5889
Coexpression	NABA_ECM_GLYCOPROTEINS	HMCN1 LAMB1 LTBP1 SSPOP CRISPLD1 OTOG	9.55e-06	191	67	6	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	HMCN1 LAMB1 LTBP1 SSPOP CRISPLD1 OTOG	1.11e-05	196	67	6	M3008
Coexpression	DESCARTES_ORGANOGENESIS_CHONDROCYTE_PROGENITORS	ADAMTS12 ATP13A5 PI15 LEPR	1.95e-05	62	67	4	MM3645
Coexpression	DESCARTES_ORGANOGENESIS_MELANOCYTES	CLEC18A FAM13A CLEC18B CLEC18C	2.49e-05	66	67	4	MM3664
Coexpression	NABA_CORE_MATRISOME	HMCN1 LAMB1 LTBP1 SSPOP CRISPLD1 OTOG	6.66e-05	270	67	6	MM17057
Coexpression	BASAKI_YBX1_TARGETS_DN	THBD FAM13A LAMB1 STOX1 CASZ1 VPS13B BICD1	7.01e-05	398	67	7	M14877
Coexpression	NABA_CORE_MATRISOME	HMCN1 LAMB1 LTBP1 SSPOP CRISPLD1 OTOG	7.37e-05	275	67	6	M5884
Coexpression	GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN	PSME4 SUSD3 CASP9 WDR82 CRISPLD1	1.44e-04	195	67	5	M4233
Coexpression	GSE12366_NAIVE_VS_MEMORY_BCELL_UP	PSME4 MEGF6 MARCHF3 TRIM17 SLC38A7	1.44e-04	195	67	5	M3178
Coexpression	GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN	SLCO5A1 PSME4 AP5Z1 LEPR MOCOS	1.51e-04	197	67	5	M6075
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	ADAMTS12 EXOC6 CLEC18A GALNT10 CELSR1 CLEC18B MEGF6 CLEC18C LAMB1 SHISA2 LTBP1 STOX1 CRISPLD1 MEX3B LEPR ZNF710 ZNF71	1.64e-06	1466	66	17	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	TGFB1I1 ADAMTS12 GALNT10 HMCN1 LAMB1 SHISA2	2.88e-07	178	67	6	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	HMCN1 SHISA2 LTBP1 USP27X CRISPLD1 NCOA5	2.88e-07	178	67	6	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HOXB7 HMCN1 LAMB1 CRISPLD1 LEPR	4.22e-07	190	67	6	9d5242759546be0089981ef1877e4ed5f81face5
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EXOC6 THBD HMCN1 LTBP1 LEPR BICD1	4.63e-07	193	67	6	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTS12 HMCN1 LAMB1 LTBP1 VPS13B BICD1	5.22e-07	197	67	6	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 MEGF6 LTBP1 CRISPLD1	5.64e-06	169	67	5	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 MEGF6 LTBP1 CRISPLD1	5.64e-06	169	67	5	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	ADAMTS12 HMCN1 LAMB1 LTBP1 NRG3	7.87e-06	181	67	5	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 GALNT10 HMCN1 USP43 CASZ1	7.87e-06	181	67	5	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	Basal\|World / shred by cell class for mouse tongue	CELSR1 MEGF6 LAMB1 LTBP1 CCNI	8.30e-06	183	67	5	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EXOC6 THBD LTBP1 NRG3 LEPR	8.30e-06	183	67	5	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TGFB1I1 ADAMTS12 HMCN1 LAMB1 LTBP1	8.75e-06	185	67	5	87c416d14ca6255bee39b16e7571553e36ee3069
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FAM13A LAMB1 LTBP1 C6 LEPR	8.98e-06	186	67	5	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FAM13A LAMB1 LTBP1 C6 LEPR	8.98e-06	186	67	5	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD CELSR1 HMCN1 MEGF6 SHISA2	9.21e-06	187	67	5	d9943e65eedab73d141eae524e2411653a751705
ToppCell	facs-Heart-LA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD CELSR1 HMCN1 MEGF6 SHISA2	9.21e-06	187	67	5	7b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	EXOC6 PFKFB4 LEPR CASZ1 BICD1	9.21e-06	187	67	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	ADAMTS12 HMCN1 LAMB1 LTBP1 LEPR	9.21e-06	187	67	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBD HMCN1 MEGF6 LTBP1 CRISPLD1	9.45e-06	188	67	5	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 MEGF6 LTBP1 CRISPLD1	9.95e-06	190	67	5	9b0ad888eb20acc011904d8593bc32bdef18d050
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 MEGF6 LTBP1 CRISPLD1	1.02e-05	191	67	5	fcdf3a747038e346a467eae8b7c293592658b53f
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HOXB7 LTBP1 CRISPLD1 LEPR	1.05e-05	192	67	5	f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TGFB1I1 ADAMTS12 HMCN1 LAMB1 LTBP1	1.05e-05	192	67	5	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB1 CASZ1 MOCOS BICD1 ZC3HAV1	1.05e-05	192	67	5	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP31 THBD HMCN1 LEPR BICD1	1.05e-05	192	67	5	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HOXB7 LTBP1 CRISPLD1 LEPR	1.05e-05	192	67	5	bcd8876235be503186f119653b39476488c0fa15
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TGFB1I1 HMCN1 MEGF6 LTBP1 PI15	1.05e-05	192	67	5	a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 MEGF6 LTBP1 CRISPLD1	1.05e-05	192	67	5	c157981b9a179925edcaabc0cb3b8805f0929004
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB1 CASZ1 MOCOS BICD1 ZC3HAV1	1.05e-05	192	67	5	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 MEGF6 LTBP1 CRISPLD1	1.05e-05	192	67	5	cd4c9b9ab17a779c154264f7459020f51e528ba5
ToppCell	15-Trachea-Endothelial-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	THBD HOXB7 HMCN1 NRG3 LEPR	1.07e-05	193	67	5	6ea0444fc3dc156997129387184e6418947f4b12
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EXOC6 THBD HMCN1 LEPR BICD1	1.07e-05	193	67	5	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	15-Trachea-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	THBD HOXB7 HMCN1 NRG3 LEPR	1.07e-05	193	67	5	b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	USP31 THBD NRG3 LEPR BICD1	1.07e-05	193	67	5	01c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	USP31 THBD NRG3 LEPR BICD1	1.10e-05	194	67	5	53a5e8863d79a052dff0758f389be5ac3883c721
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB1I1 THBD LAMB1 LTBP1 PI15	1.16e-05	196	67	5	2aa1acea3cefb3dbe3afdb04875c96b927e9d860
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HMCN1 LAMB1 LTBP1 PI15	1.16e-05	196	67	5	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HMCN1 LAMB1 LTBP1 PI15	1.16e-05	196	67	5	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB1I1 THBD LAMB1 LTBP1 PI15	1.16e-05	196	67	5	59ca204c96149fdff08bc524cfa832a30e60e8a4
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	USP31 THBD NRG3 LEPR BICD1	1.16e-05	196	67	5	29ed8b1c4cd730db8632fde6eece404f1883a86d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB1I1 THBD LAMB1 LTBP1 PI15	1.16e-05	196	67	5	d06a29775a41223e02728615af519a18f7e82e8b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	USP31 ADGRB1 LAMB1 PI15 CRISPLD1	1.16e-05	196	67	5	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	TGFB1I1 ADAMTS12 HMCN1 LAMB1 LTBP1	1.27e-05	200	67	5	082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	TGFB1I1 ADAMTS12 HMCN1 SHISA2 LTBP1	1.27e-05	200	67	5	ca777a7d001848f6d01c613ff2bda7e4f3e20521
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	TGFB1I1 ADAMTS12 HMCN1 LAMB1 LTBP1	1.27e-05	200	67	5	731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell	droplet-Skin-nan-21m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM13A HMCN1 SHISA2 PI15 CRISPLD1	1.27e-05	200	67	5	69295705fc614c2687f2b6c8e6aa0c6717841008
ToppCell	(5)_Fibroblast-B_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	TGFB1I1 ADAMTS12 HMCN1 LAMB1 LTBP1	1.27e-05	200	67	5	9bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Abcc9_(Mural.Acta2Rgs5.Abcc9)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS12 ATP13A5 LEPR MOCOS	3.92e-05	126	67	4	2b06adfb00a557bd90ad93719548a49f9ae9edeb
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Abcc9_(Mural.Acta2Rgs5.Abcc9)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ADAMTS12 ATP13A5 LEPR MOCOS	3.92e-05	126	67	4	43e7b226a195ab2068518b3a9ffd2192129e8ae4
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tfh\|GI_small-bowel / Manually curated celltypes from each tissue	TGFB1I1 CLEC18C SHISA2 C6	3.92e-05	126	67	4	d0d3e25e4fb074a76313fc90d8c3828b1d8ea486
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 GJD2 PROM2 SSPOP	5.75e-05	139	67	4	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	368C-Fibroblasts-Fibroblast-H-\|368C / Donor, Lineage, Cell class and subclass (all cells)	MEGF6 TRIM17 LAMB1 POMT1	8.13e-05	152	67	4	dbfb4d4de36ef9f5c7da1950baa915b12788685e
ToppCell	368C-Fibroblasts-Fibroblast-H\|368C / Donor, Lineage, Cell class and subclass (all cells)	MEGF6 TRIM17 LAMB1 POMT1	8.13e-05	152	67	4	9f3682da00fd627e80aa820ecc6f5fed23b9738a
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3\|TCGA-Skin / Sample_Type by Project: Shred V9	HMCN1 PHLPP1 PI15 CRISPLD1	9.68e-05	159	67	4	fb222c42f66901852b01cec073ec0732245ee973
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 HMCN1 PROM2 TRIM17	1.04e-04	162	67	4	36ddebe3bb172c992739353b7b049b2dde98b559
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT10 AP5Z1 UBR4 USP27X	1.04e-04	162	67	4	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-2_PVALB_TAC1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 HOXB7 GJD2 CLEC18C	1.17e-04	167	67	4	d5b62934b3533d65e552adfc99a65d29f874cbb0
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 MARCHF3 SHISA2	1.20e-04	168	67	4	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 MARCHF3 SHISA2	1.20e-04	168	67	4	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS12 SHISA2 LTBP1 CRISPLD1	1.22e-04	169	67	4	1d5ce2c97f7ef7bdc9f861938077a9aa31d84db6
ToppCell	368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS12 SHISA2 LTBP1 CRISPLD1	1.22e-04	169	67	4	58098f8801ca941aeddafb47e88ab0df8b9edb57
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	THBD PHLPP1 USP27X CASZ1	1.25e-04	170	67	4	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 SHISA2 BICD1	1.25e-04	170	67	4	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 SHISA2 BICD1	1.25e-04	170	67	4	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MEGF6 SHISA2 BICD1	1.25e-04	170	67	4	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 HMCN1 PROM2 USP43	1.34e-04	173	67	4	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AP5Z1 WDR82 BICD1 ZC3HAV1	1.34e-04	173	67	4	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 GALNT10 HMCN1 USP43	1.34e-04	173	67	4	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS12 MEGF6 USP27X PI15	1.40e-04	175	67	4	b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 HMCN1 PROM2 CRISPLD1	1.40e-04	175	67	4	787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS12 MEGF6 USP27X PI15	1.40e-04	175	67	4	7ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	THBD SETD2 MEGF6 LEPR	1.43e-04	176	67	4	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CELSR1 SLC38A7 CASP9 BICD1	1.43e-04	176	67	4	792f414f5092aba14260b8e16378e793a822498e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 HMCN1 PROM2 CRISPLD1	1.46e-04	177	67	4	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXB7 NWD1 CRISPLD1 BICD1	1.46e-04	177	67	4	d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEGF6 LTBP1 PI15 CRISPLD1	1.53e-04	179	67	4	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD CELSR1 HMCN1 MEGF6	1.59e-04	181	67	4	cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGFB1I1 THBD LAMB1 LTBP1	1.59e-04	181	67	4	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 GALNT10 NRG3 CASZ1	1.59e-04	181	67	4	22363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CELSR1 PROM2 MUC5B STOX1	1.63e-04	182	67	4	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLCO5A1 THBD CELSR1 HMCN1	1.63e-04	182	67	4	f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HMCN1 CRISPLD1 LEPR	1.66e-04	183	67	4	c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 HMCN1 MEGF6 SHISA2	1.66e-04	183	67	4	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB1 CASZ1 MOCOS BICD1	1.66e-04	183	67	4	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HMCN1 CRISPLD1 LEPR	1.66e-04	183	67	4	c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCell	facs-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HMCN1 CRISPLD1 LEPR	1.66e-04	183	67	4	92eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 MEGF6 CRISPLD1	1.66e-04	183	67	4	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO5A1 CLEC18A NWD1 BICD1	1.66e-04	183	67	4	ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MUC5B SSPOP OTOG	1.70e-04	184	67	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	PND14\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THBD HMCN1 PI15 CASZ1	1.70e-04	184	67	4	1bfee4eb121e76a79f48b06b45f05d124fbbedba
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MUC5B SSPOP OTOG	1.70e-04	184	67	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 MUC5B SSPOP OTOG	1.70e-04	184	67	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLEC18A CLEC18B CLEC18C CRISPLD1	1.73e-04	185	67	4	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	LPS_only\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACSL4 MARCHF3 VPS13B ZC3HAV1	1.73e-04	185	67	4	a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLEC18A CLEC18B CLEC18C CRISPLD1	1.73e-04	185	67	4	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB1 CASZ1 MOCOS BICD1	1.77e-04	186	67	4	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB1 CASZ1 MOCOS BICD1	1.77e-04	186	67	4	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB1 CASZ1 MOCOS BICD1	1.77e-04	186	67	4	b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB1I1 NWD1 ADGRB1 LTBP1	1.81e-04	187	67	4	ddfc2d1d9fcc3d8e4d3d015576bb17eebf44ada9
ToppCell	droplet-Pancreas-Exocrine-24m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBD HOXB7 HMCN1 CRISPLD1	1.81e-04	187	67	4	a178b1fed80a0bf83aedb6262493ee17374734b5
Disease	idiopathic pulmonary fibrosis (is_implicated_in)	SETD2 EHMT2 MUC5B	8.89e-07	9	66	3	DOID:0050156 (is_implicated_in)
Disease	Sterility, Reproductive	EHMT2 LEPR	4.91e-05	5	66	2	C4074771
Disease	Subfertility	EHMT2 LEPR	4.91e-05	5	66	2	C0729353
Disease	Infertility	EHMT2 LEPR	4.91e-05	5	66	2	C0021359
Disease	lymphocyte count	EXOC6 SETD2 NWD1 PSME4 PHLPP1 CLEC18C MEX3B LEPR CASZ1 ZNF710 ZNF71 ZC3HAV1	8.68e-05	1464	66	12	EFO_0004587
Disease	response to anti-thyroid drug, Drug-induced agranulocytosis	EHMT2 MOCOS	1.37e-04	8	66	2	EFO_0007838, HP_0012235
Disease	mean platelet volume	ACSL4 SETD2 FAM13A PATE1 LTBP1 PFKFB4 TNFRSF21 LEPR ZNF710	4.30e-04	1020	66	9	EFO_0004584
Disease	Hamman-Rich syndrome	FAM13A MUC5B	4.41e-04	14	66	2	C0085786
Disease	interstitial lung disease	FAM13A MUC5B NRG3	4.62e-04	67	66	3	EFO_0004244
Disease	Astrocytosis	TNFRSF21 LEPR	6.56e-04	17	66	2	C3887640
Disease	Gliosis	TNFRSF21 LEPR	6.56e-04	17	66	2	C0017639
Disease	Usual Interstitial Pneumonia	FAM13A MUC5B	8.22e-04	19	66	2	C4721509
Disease	Hamman-Rich Disease	FAM13A MUC5B	8.22e-04	19	66	2	C4721508
Disease	Familial Idiopathic Pulmonary Fibrosis	FAM13A MUC5B	9.12e-04	20	66	2	C4721952
Disease	Idiopathic Pulmonary Fibrosis	FAM13A MUC5B	1.01e-03	21	66	2	C1800706
Disease	colon carcinoma	PI15 CRISPLD1	1.55e-03	26	66	2	EFO_1001950
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment	FAM13A LAMB1 WDR82	1.70e-03	105	66	3	EFO_0007788, EFO_0008007, EFO_0008343
Disease	Myopia	GJD2 USP43 NRG3 MEX3B VPS13B	1.72e-03	385	66	5	HP_0000545
Disease	glomerular filtration rate, response to platinum based chemotherapy	MARCHF3 NRG3	1.79e-03	28	66	2	EFO_0004647, EFO_0005208
Disease	proteinuria (implicated_via_orthology)	C6 LEPR	2.06e-03	30	66	2	DOID:576 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSPQTHRFMNVCFCC	ACSL4	446	O60488
PQRINMCGQINLVCF	ATP13A5	471	Q4VNC0
HVCLCNNETPNRVML	BICD1	521	Q96G01
TMFVCNTLQPGCNQA	GJD2	51	Q9UKL4
VGNRNPSRAACQMLC	ADGRB1	176	O14514
QCLCPNQHCEFRMRG	CASZ1	1226	Q86V15
LHCMACNQLLQFRGS	CCNI	186	Q14094
KACVSQLNGMVFCPH	EHMT2	521	Q96KQ7
QPMAGCARVAQCAQA	AP5Z1	541	O43299
CHLNPCENMGACVRS	CELSR1	1911	Q9NYQ6
LSGMCQPHRSCNINE	ADAMTS12	366	P58397
PTLKCQTFCQRHGLM	NWD1	11	Q149M9
FNAHMGICVQACPCV	MUC5B	5401	Q9HC84
CCSPGQRSGMLHRNA	NRG3	476	P56975
SPGATELNMCHSNCQ	MIS18BP1	541	Q6P0N0
CSESDHRIFMNTCNP	GALNT10	566	Q86SR1
TNFRVVICHLPCMNG	LTBP1	396	Q14766
LCRVPCNTMFGSQHQ	PDXDC2P	201	Q6P474
CTVNIMFGTPQEHRN	NCOA5	266	Q9HCD5
LHACQRGVCMTNCPT	PFKFB4	26	Q16877
QHNTMGRNCEQCKPF	LAMB1	366	P07942
PQKGSFQMVHCNCSV	LEPR	176	P48357
RFQVLGPCHRCQMIC	MOCOS	801	Q96EN8
GPCHRCQMICIDQQT	MOCOS	806	Q96EN8
RMNVHNLATVFGPNC	FAM13A	186	O94988
PGKVAQTACMSACQH	EXOC6	651	Q8TAG9
CLEQNVHCGPNRMCF	HMCN1	5476	Q96RW7
NMHCAPFEQNLSGVC	HOXB7	86	P09629
QMSQGVCVFCHLLAR	POMT1	251	Q9Y6A1
CTFSIMENNGQPCIN	C6	611	P13671
SNRIGCAINLCHNMN	CRISPLD1	176	Q9H336
SMEPCGHCLIINNVN	CASP9	156	P55211
TQSPFNDRPMCRICH	MARCHF3	61	Q86UD3
VQCRMCHLQFPGEKC	PATE1	46	Q8WXA2
VMSPCHTCVCQRGSF	OTOG	961	Q6ZRI0
VPCGHNLFCMECANR	MEX3B	531	Q6ZN04
SPCANRNGSCMHRCQ	MEGF6	246	O75095
CCISSPSHLMSQQYR	MRPS5	71	P82675
CPSNHQMVGSGLLTC	SUSD3	61	Q96L08
PHRCQMFCNQTACPA	THBD	401	P07204
QCPENMLFRSAEQCH	SSPOP	2886	A2VEC9
GMFQSNATCAPHTVC	TNFRSF21	136	O75509
MPHRNLTGSCNVNCG	SLCO5A1	546	Q9H2Y9
RSQTNCCLPEGTMNN	SHISA2	201	Q6UWI4
NAMPTICFGFQCHVS	SLC38A7	246	Q9NVC3
KCDPNMCTNRLVQHG	SETDB1	786	Q15047
PCRMSCQNHGRLNIS	CLEC18A	231	A5D8T8
PCRMSCQNHGRLNIS	CLEC18B	231	Q6UXF7
PCRMSCQNHGRLNIS	CLEC18C	231	Q8NCF0
TCFMNCIVQALTHTP	USP27X	86	A6NNY8
HGNTCFMNAVVQCLS	USP43	106	Q70EL4
CQGLMHLQGKPVCSF	WDR82	141	Q6UXN9
CAFVTNQRTHEQMGP	PROM2	171	Q8N271
APISHCQSCQCFRDM	STOX1	236	Q6ZVD7
QMLLPNQCSFCAHQR	ZNF592	746	Q92610
KHQNVRPFVCTECGM	ZNF710	456	Q8N1W2
FVPHCCSVITQLTMN	PSME4	646	Q14997
GNCSRFMNHSCEPNC	SETD2	1621	Q9BYW2
SMLCKNALAQHCRFP	ZNF862	1006	O60290
PVMTTCGHNFCRACI	TRIM17	26	Q9Y577
FPGHQKLCQFCISSM	VPS13B	3081	Q7Z7G8
CMLHPICLSNSFQRQ	PHLPP1	1516	O60346
RCGFCNQPIRHKMVT	TGFB1I1	286	O43294
NCRFPNCLRSHNLMD	ZC3HAV1	181	Q7Z2W4
SNRIGCAIHTCQNMN	PI15	181	O43692
RNHGNTCFMNATLQC	USP31	131	Q70CQ4
MNHPGLVCCVQQTTG	UBR4	2171	Q5T4S7
VCPECGRAFSQNMHL	ZNF71	271	Q9NQZ8