Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	PP2C_BS	PPM1B PPM1G	6.56e-04	12	60	2	IPR000222
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH6	9.01e-04	14	60	2	IPR024317
Domain	PP2C_SIG	PPM1B PPM1G	9.01e-04	14	60	2	SM00331
Domain	Dynein_HC_stalk	DNAH3 DNAH6	9.01e-04	14	60	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH6	9.01e-04	14	60	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH6	9.01e-04	14	60	2	PF08393
Domain	MT	DNAH3 DNAH6	9.01e-04	14	60	2	PF12777
Domain	AAA_8	DNAH3 DNAH6	9.01e-04	14	60	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH6	9.01e-04	14	60	2	IPR011704
Domain	AAA_5	DNAH3 DNAH6	9.01e-04	14	60	2	PF07728
Domain	DHC_fam	DNAH3 DNAH6	1.04e-03	15	60	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH6	1.04e-03	15	60	2	IPR004273
Domain	PPM_1	PPM1B PPM1G	1.04e-03	15	60	2	PS01032
Domain	Dynein_heavy	DNAH3 DNAH6	1.04e-03	15	60	2	PF03028
Domain	PP2C	PPM1B PPM1G	1.34e-03	17	60	2	IPR015655
Domain	PP2C	PPM1B PPM1G	1.68e-03	19	60	2	PF00481
Domain	PP2Cc	PPM1B PPM1G	1.86e-03	20	60	2	SM00332
Domain	PPM-type_phosphatase_dom	PPM1B PPM1G	1.86e-03	20	60	2	IPR001932
Domain	-	PPM1B PPM1G	1.86e-03	20	60	2	3.60.40.10
Domain	PPM_2	PPM1B PPM1G	1.86e-03	20	60	2	PS51746
Domain	HR1_rho-bd	PSMC5 TRIP10	2.90e-03	25	60	2	IPR011072
Domain	SH3	MAP3K9 TJP2 ARHGEF16 TRIP10	5.12e-03	216	60	4	SM00326
Domain	SH3	MAP3K9 TJP2 ARHGEF16 TRIP10	5.12e-03	216	60	4	PS50002
Domain	SH3_domain	MAP3K9 TJP2 ARHGEF16 TRIP10	5.46e-03	220	60	4	IPR001452
Domain	PH	DOCK11 IRS1 PLEKHH2 ARHGEF16	6.28e-03	229	60	4	PF00169
Pathway	WP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY	SREBF2 RPS6KA6 MAP3K9 IRS1 TRIP10	5.41e-05	132	44	5	M39338
Pubmed	Functional association between the insulin receptor and the transmembrane protein-tyrosine phosphatase LAR in intact cells.	PTPRF IRS1	3.13e-06	2	62	2	8995282
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	CSDE1 GSPT2 DOCK11 AHNAK PSMC5 SRPK1 ATP2B1	7.09e-06	399	62	7	37536630
Pubmed	Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.	RAB3GAP2 PSMC5 CHD8 ATP2B1	8.13e-06	71	62	4	36305789
Pubmed	Modulation of insulin signal transduction by eutopic overexpression of the receptor-type protein-tyrosine phosphatase LAR.	PTPRF IRS1	9.37e-06	3	62	2	8732688
Pubmed	Regulation of acetylation at the major histocompatibility complex class II proximal promoter by the 19S proteasomal ATPase Sug1.	PSMC5 CREBBP	9.37e-06	3	62	2	18662994
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PTPRF SNX6 AHNAK RRP12 PEX19 PSMC5 CRYBG3 ATP2B1 PPM1B PPM1G	1.55e-05	1049	62	10	27880917
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	CSDE1 DNAH3 SNX6 WDR33 PSMC5 SRPK1 DNAH6 ATP2B1 PPM1G	1.85e-05	847	62	9	35235311
Pubmed	SREBP transcriptional activity is mediated through an interaction with the CREB-binding protein.	SREBF2 CREBBP	1.87e-05	4	62	2	8918891
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH3 DNAH6	1.87e-05	4	62	2	11175280
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CSDE1 AHNAK RRP12 TJP2 PSMC5 SRPK1 CHD8 PPM1G	2.05e-05	653	62	8	22586326
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK11 AHNAK RAB3GAP2 MAP3K9 TJP2 IRS1 CRYBG3 ARHGEF16 ATP2B1	2.10e-05	861	62	9	36931259
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	CSDE1 SNX6 CFAP36 AHNAK RRP12 A2ML1 TJP2 PSMC5 ZNF207 TRIP10 PPM1G	2.67e-05	1367	62	11	32687490
Pubmed	DHHC protein family targets different subsets of glioma stem cells in specific niches.	GSPT2 SNX6 IRS1	2.83e-05	33	62	3	30658672
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	CSDE1 DOCK11 WDR33 AHNAK TJP2 ZNF207 ARHGEF16 TRIP10 PPM1G	3.41e-05	916	62	9	32203420
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	CSDE1 AHNAK RAB3GAP2 PSMC5 CC2D1B CRYBG3 ATP2B1 PPM1G	3.64e-05	708	62	8	39231216
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CSDE1 VPS45 AHNAK RRP12 PEX19 TJP2 PSMC5 SRPK1 ATP2B1 PPM1G HNRNPR	4.29e-05	1440	62	11	30833792
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	COL3A1 SPATA7 AHNAK RAB3GAP2 PEX19 ZNF207 CHD8 IRS1 DNAH6 TRIP10 ATP2B1	4.60e-05	1451	62	11	30550785
Pubmed	The embryonic RNA helicase gene (ERH): a new member of the DEAD box family of RNA helicases.	COL3A1 TBXT	4.67e-05	6	62	2	8948440
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	CSDE1 WDR33 A2ML1 SRPK1 HNRNPR	4.67e-05	220	62	5	24550385
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CSDE1 GSPT2 SNX6 AHNAK RAB3GAP2 TJP2 PSMC5 CC2D1B TRIP10 PPM1G HNRNPR	4.72e-05	1455	62	11	22863883
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CSDE1 WDR33 AHNAK RAB3GAP2 TJP2 CHD8 CREBBP	5.46e-05	549	62	7	38280479
Pubmed	Early embryonic death in mice lacking the beta-catenin-binding protein Duplin.	TBXT CHD8	6.53e-05	7	62	2	15367660
Pubmed	The 19S proteasome positively regulates histone methylation at cytokine inducible genes.	PSMC5 CREBBP	6.53e-05	7	62	2	19660582
Pubmed	Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.	PTPRF IRS1	6.53e-05	7	62	2	10660596
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	CSDE1 SNX6 VPS45 AHNAK RAB3GAP2 ARHGEF16 TMEM87A	6.75e-05	568	62	7	37774976
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	WDR33 AHNAK RRP12 GON4L CHD8 PPM1G	7.32e-05	394	62	6	27248496
Pubmed	Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.	WDR33 RRP12 PSMC5 HNRNPR	8.53e-05	129	62	4	28973437
Pubmed	MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.	CREBBP MEF2A	8.69e-05	8	62	2	16043483
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	CSDE1 RRP12 SRPK1 PPM1B HNRNPR	9.90e-05	258	62	5	37794589
Pubmed	Identification of novel CBP interacting proteins in embryonic orofacial tissue.	TRIP10 CREBBP	1.12e-04	9	62	2	15752756
Pubmed	N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells.	PPM1B PPM1G	1.12e-04	9	62	2	23088624
Pubmed	The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.	TJP2 TBXT	1.12e-04	9	62	2	20704721
Pubmed	Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells.	TBXT CREBBP	1.12e-04	9	62	2	16801560
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CSDE1 AHNAK RRP12 A2ML1 PSMC5 SRPK1 CHD8 ATP2B1 CREBBP HNRNPR	1.31e-04	1353	62	10	29467282
Pubmed	Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.	PPM1B PPM1G	1.39e-04	10	62	2	20801214
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	CSDE1 AHNAK ZNF207 CHD8 CREBBP HNRNPR	1.41e-04	444	62	6	34795231
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	CSDE1 SNX6 VPS45 AHNAK PSMC5 TMEM87A	1.49e-04	449	62	6	31732153
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CSDE1 SREBF2 GON4L SRPK1 CC2D1B CHD8 CRYBG3	1.56e-04	650	62	7	38777146
Pubmed	Trim33 is required for appropriate development of pre-cardiogenic mesoderm.	TBXT MEF2A	1.70e-04	11	62	2	30940539
Pubmed	Deregulation of Rb-E2F1 axis causes chromosomal instability by engaging the transactivation function of Cdc20-anaphase-promoting complex/cyclosome.	SREBF2 CREBBP	1.70e-04	11	62	2	25368385
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	SNX6 WDR33 RAB3GAP2 PSMC5 SRPK1 CREBBP PPM1G	1.87e-04	670	62	7	22990118
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	WDR33 RAB3GAP2 PSMC5 ZNF207 CHD8 CRYBG3	1.96e-04	472	62	6	38943005
Pubmed	Human transcription factor protein interaction networks.	WDR33 RRP12 GON4L PSMC5 TBXT CHD8 CREBBP MEF2A PPM1G HNRNPR	2.04e-04	1429	62	10	35140242
Pubmed	Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo.	TJP2 TBXT	2.04e-04	12	62	2	23406901
Pubmed	A human MAP kinase interactome.	INTS6L CSDE1 CFAP36 SREBF2 CHD8 CREBBP	2.29e-04	486	62	6	20936779
Pubmed	Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis.	TJP2 TBXT	2.41e-04	13	62	2	23213408
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	PTPRF WDR33 AHNAK RRP12 PSMC5 CHD8 IRS1 ATP2B1 HNRNPR	2.68e-04	1203	62	9	29180619
Pubmed	New sequence variants associated with bone mineral density.	HROB ADAM19	2.81e-04	14	62	2	19079262
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH6	2.81e-04	14	62	2	9373155
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	CSDE1 AHNAK A2ML1 PPM1B HNRNPR	2.97e-04	327	62	5	31409639
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	CSDE1 CFAP36 AHNAK GON4L PSMC5	3.10e-04	330	62	5	32529326
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	ADAM19 RPS6KA6 SRPK1 IRS1 ATP2B1 CREBBP PPM1B	3.15e-04	730	62	7	34857952
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	COL3A1 AHNAK PEX19 CHD8 CREBBP	3.19e-04	332	62	5	37433992
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	CSDE1 PSMC5 ZNF207 SRPK1 ATP2B1 PPM1B PPM1G HNRNPR	3.19e-04	971	62	8	33306668
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PTPRF SNX6 PEX19 TJP2 PSMC5 SRPK1 ATP2B1 PPM1G	3.26e-04	974	62	8	28675297
Pubmed	KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.	AHNAK CC2D1B	3.69e-04	16	62	2	24960163
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	AHNAK RRP12 GON4L PSMC5 SRPK1 PPM1G	4.29e-04	547	62	6	37267103
Pubmed	Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.	COL3A1 TBXT	4.70e-04	18	62	2	12571105
Pubmed	Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.	PSMC5 TRIP10	4.70e-04	18	62	2	7776974
Pubmed	ABCE1 is a highly conserved RNA silencing suppressor.	PTPRF RRP12 ZNF207 PPM1G	4.91e-04	204	62	4	25659154
Pubmed	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.	SREBF2 CREBBP	5.24e-04	19	62	2	16799563
Pubmed	Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation.	PEX19 PSMC5	5.24e-04	19	62	2	38225382
Pubmed	The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo.	TJP2 TBXT	5.24e-04	19	62	2	17507402
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	CSDE1 RRP12 A2ML1 PSMC5 ZNF207 PPM1G	5.38e-04	571	62	6	37167062
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	WDR33 MEF2A HNRNPR	5.49e-04	89	62	3	22446626
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	CSDE1 GSPT2 WDR33 RRP12 ZNF207 SRPK1 HNRNPR	5.73e-04	807	62	7	22681889
Pubmed	Germline Chd8 haploinsufficiency alters brain development in mouse.	CHD8 HNRNPR	5.82e-04	20	62	2	28671691
Pubmed	Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins.	SRPK1 PPM1G	5.82e-04	20	62	2	22504172
Pubmed	Identification of novel ARF binding proteins by two-hybrid screening.	AHNAK PEX19	6.42e-04	21	62	2	16582619
Pubmed	The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.	CSDE1 RRP12 SRPK1 PPM1G	6.52e-04	220	62	4	31822558
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	CSDE1 WDR33 AHNAK ZNF207 PPM1G	7.33e-04	399	62	5	35987950
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CSDE1 RAB3GAP2 ZNF207 CHD8 CREBBP MEF2A PPM1G HNRNPR	7.40e-04	1103	62	8	34189442
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	CSDE1 PSMC5 SRPK1 HNRNPR	7.82e-04	231	62	4	36597993
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	TJP2 IRS1 ARHGEF16	8.17e-04	102	62	3	15778465
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	AHNAK GON4L SRPK1 HNRNPR	8.21e-04	234	62	4	36243803
Pubmed	Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1.	PSMC5 ZNF207	8.41e-04	24	62	2	29871923
Pubmed	Preferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.	ADAM19 TRIP10	8.41e-04	24	62	2	25825872
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CSDE1 GSPT2 VPS45 RAB3GAP2 PEX19 TJP2 CRYBG3 PPM1G	9.11e-04	1139	62	8	36417873
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	PEX19 SRPK1 PPM1G	9.13e-04	106	62	3	31024071
Pubmed	Regulation of planar cell polarity by Smurf ubiquitin ligases.	TBXT PPM1B	9.14e-04	25	62	2	19379695
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SNX6 AHNAK RAB3GAP2 RRP12 PEX19 PSMC5 PPM1G HNRNPR	9.63e-04	1149	62	8	35446349
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	AHNAK RRP12 SRPK1 HNRNPR	9.73e-04	245	62	4	21182205
Pubmed	SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing.	ZNF207 MEF2A	9.89e-04	26	62	2	26586428
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	AHNAK ZNF207 SRPK1 CHD8	1.06e-03	251	62	4	31076518
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	WDR33 RRP12 PPM1G HNRNPR	1.06e-03	251	62	4	28077445
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	AHNAK PSMC5 ZNF207 SRPK1 PPM1B HNRNPR	1.14e-03	660	62	6	32780723
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SNX6 WDR33 CFAP36 RAB3GAP2 RRP12 PEX19 PSMC5 CRYBG3 HNRNPR	1.28e-03	1496	62	9	32877691
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	ZBTB2 ZNF207 ATP2B1 CREBBP PPM1G	1.29e-03	453	62	5	29656893
Pubmed	A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.	CHD8 PPM1G HNRNPR	1.34e-03	121	62	3	22412018
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	WDR33 CHD8 CREBBP MEF2A	1.35e-03	268	62	4	33640491
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	INTS6L FAM193B FER1L4 GON4L CPXM1 ZNF207 CC2D1B CHD8	1.38e-03	1215	62	8	15146197
Pubmed	Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.	COL3A1 AHNAK	1.41e-03	31	62	2	32546759
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CSDE1 PTPRF RAB3GAP2 RRP12 SREBF2 PSMC5 PPM1G	1.41e-03	942	62	7	31073040
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	CSDE1 SNX6 PSMC5 ATP2B1 HNRNPR	1.42e-03	463	62	5	34901782
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	CSDE1 WDR33 ZNF207 PPM1G HNRNPR	1.50e-03	469	62	5	37314180
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	WDR33 CFAP36 AHNAK PSMC5 PPM1B	1.68e-03	481	62	5	28190767
Pubmed	Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.	CHD8 CREBBP	1.69e-03	34	62	2	30894540
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	COL3A1 CSDE1 AHNAK RRP12 TJP2 SRPK1 PPM1G HNRNPR	1.70e-03	1257	62	8	36526897
Pubmed	An inter-species protein-protein interaction network across vast evolutionary distance.	FAM193B HROB PEX19 PSMC5 TRIP10	1.71e-03	483	62	5	27107014
Pubmed	The LIFEdb database in 2006.	SPATA7 CSDE1 CCDC184 TJP2 PLEKHH2 MEF2A	1.77e-03	720	62	6	16381901
GeneFamily	Dyneins, axonemal	DNAH3 DNAH6	8.41e-04	17	46	2	536
GeneFamily	Protein phosphatases, Mg2+/Mn2+ dependent	PPM1B PPM1G	8.41e-04	17	46	2	701
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	DOCK11 IRS1 PLEKHH2 ARHGEF16	1.84e-03	206	46	4	682
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC184 ADAM19 SWT1 STX11 TMEM87A	3.84e-06	169	62	5	573f85075d83a4baba41c3e24dc4d9831823a5e5
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC184 ADAM19 SWT1 STX11 TMEM87A	3.84e-06	169	62	5	a24d12199b1a6d9cb243b3a68f4109d3a30b2dcb
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAM19 AHNAK TJP2 JADE1 ATP2B1	6.78e-06	190	62	5	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	BLOOD--(1)_T_cell-(1)_EM_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ADAM19 SNX6 PI16 AHNAK ATP2B1	7.69e-06	195	62	5	4b8831ed8fb73579f49604eeda8a3b2344e69f0e
Computational	Genes in the cancer module 397.	FER1L4 GON4L SRPK1 ARHGEF16 DNAH6	6.20e-05	121	38	5	MODULE_397
Disease	autism spectrum disorder (implicated_via_orthology)	CSDE1 CHD8 CREBBP MEF2A	2.47e-04	152	59	4	DOID:0060041 (implicated_via_orthology)
Disease	Endogenous Hyperinsulinism	COL3A1 IRS1	1.24e-03	26	59	2	C1257963
Disease	Exogenous Hyperinsulinism	COL3A1 IRS1	1.24e-03	26	59	2	C1257964
Disease	Compensatory Hyperinsulinemia	COL3A1 IRS1	1.24e-03	26	59	2	C1257965
Disease	Hyperinsulinism	COL3A1 IRS1	1.44e-03	28	59	2	C0020459
Disease	Large cell carcinoma of lung	RPS6KA6 ALPK3	1.88e-03	32	59	2	C0345958
Disease	fibromuscular dysplasia	TJP2 ATP2B1	3.52e-03	44	59	2	EFO_1000938

Protein segments in the cluster

Peptide	Gene	Start	Entry
AITDEGMDVPLAMEE	PI16	91	Q6UXB8
MALDGPEQMELEEGK	PSMC5	1	P62195
QDDEGDPLMMMDEEI	CHD8	1706	Q9HCK8
DTEGDIGKIEVIPMM	CRYBG3	1626	Q68DQ2
EEGDMLDPGLVMTGT	ADAM19	616	Q9H013
GEVEEMTEKPEMTAE	CFAP36	306	Q96G28
LEMGKDVDDPMVSQG	A2ML1	1106	A8K2U0
EGEVGEEIEMTPMVF	ALPK3	1576	Q96L96
SLDDMDVDKDPGGML	ARHGEF16	131	Q5VV41
GESKGEPRSEMMEED	CREBBP	1011	Q92793
VMEMSDKPGEHELGE	CPXM1	336	Q96SM3
KGDMDVSLPKVEGDM	AHNAK	3106	Q09666
QGMIEIVEEGDMKGE	CSDE1	616	O75534
MEMQPLKSEEGGDGD	ATP2B1	331	P20020
MMDQEEKTEEGSGPC	PCP2	1	Q8IVA1
KGMMIDEADEFVAGP	INTS6L	591	Q5JSJ4
EVSEMEMDLGAIPDL	RAB3GAP2	981	Q9H2M9
QEKMGMTEEEAPCGL	IL31RA	216	Q8NI17
PPEEEGEMEETGDMM	FER1L4	1041	A9Z1Z3
PPEESGQEMMEEKEE	GSPT2	171	Q8IYD1
MDEMNGKEIEGEEIE	HNRNPR	391	O43390
VLASMELEEPGMELE	HROB	161	Q8N3J3
GEVNGLKMVDEPMEE	RPS6KA6	26	Q9UK32
LKMVDEPMEEGEADS	RPS6KA6	31	Q9UK32
SKGMMPPLSEEEELE	MEF2A	281	Q02078
PREEETGTEEYMKMD	IRS1	931	P35568
EFTEGKDMEEMEIPE	PLEKHH2	221	Q8IVE3
EELTKAMEGLGMDEG	PEX19	151	P40855
DDKEMVIEDALPGQM	DNAH6	4071	Q9C0G6
PNIDEEGAMKEDAGM	DOCK11	1671	Q5JSL3
GIRKDMIAPEEGEVM	DNAH3	241	Q8TD57
DDVFLPKDMDGVEMD	FAM193B	846	Q96PV7
PKDMDGVEMDETDRE	FAM193B	851	Q96PV7
GQGKDMMEEEAPEER	GON4L	1911	Q3T8J9
GPEDMLLGMDEAEDD	CC2D1B	31	Q5T0F9
GDEPMDFKINTDEIM	COL3A1	1221	P02461
GEEKGGLRIDMEDKM	CCDC168	5011	Q8NDH2
ALEGPEVDGFVKDMM	SCGN	216	O76038
MEDGLLEIMTKDGGD	CCDC184	1	Q52MB2
SLMEMEDEDSEGPGS	MAP3K9	671	P80192
MMGAEELTKEDEMPV	PTPRF	266	P10586
EEEEEEMMVPGMEGK	PPM1G	306	O15355
GRPEKMDDEDPIMGT	SIGLEC5	471	O15389
EEIMEKSGEEGMPDL	PPM1B	321	O75688
MQEIEEMEKESGPGQ	SRPK1	286	Q96SB4
LELTNEEFKEMGMPE	JADE1	151	Q6IE81
PGELMSMEIDLEDDV	SWT1	361	Q5T5J6
AKGEDEEMADPMEDV	RRP12	1171	Q5JTH9
MAEGEDLSLMEEDKG	TRIP10	561	Q15642
SEGKMEGMDDDPEDR	TJP2	886	Q9UDY2
DEEEEGTMMKAKGDL	ZBED2	6	Q9BTP6
EIMGKEVSGDQIEDM	STX11	166	O75558
EDMGTVKEMLPDDPT	RFX8	451	Q6ZV50
AAEMDLEDGGEMPKQ	SLC7A7	491	Q9UM01
MDDSGELGGLETMET	SREBF2	1	Q12772
SGEPQIEDDMLKEEM	SPATA7	126	Q9P0W8
EDSGPGMKVLLMDKE	VPS45	16	Q9NRW7
KERSDHKEMMEEPGD	TBXT	221	O15178
MMEGLDDGPDFLSEE	SNX6	1	Q9UNH7
ELEIYGMEGIPEKDM	ZNF207	76	O43670
DLGKDAMEVPEAGMI	ZBTB2	301	Q8N680
EIEMTIPGLDWGMEE	WDR33	466	Q9C0J8
VIDEMGFMKTPDEDE	TTLL7	56	Q6ZT98
DEQKEPMLKESFEGM	TMEM87A	481	Q8NBN3