Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenototal anomalous pulmonary venous connection, intracardiac

CFC1 CFC1B

2.13e-052652MP:0010443
DomainZINC_FINGER_C2H2_2

ZNF469 ZNF527 ZNF672 ZNF497 ZNF608 KLF6 MZF1 ZNF559 ZNF423 ZFP64 KCMF1 ZNF407 ZNF324B ZNF467

1.69e-057758914PS50157
DomainZINC_FINGER_C2H2_1

ZNF469 ZNF527 ZNF672 ZNF497 ZNF608 KLF6 MZF1 ZNF559 ZNF423 ZFP64 KCMF1 ZNF407 ZNF324B ZNF467

1.74e-057778914PS00028
DomainARHGEF5_35

ARHGEF35 ARHGEF5

2.25e-052892PF15441
DomainTis11B_N

ZFP36L1 ZFP36L2

2.25e-052892PF04553
DomainARHGEF5/35_N

ARHGEF35 ARHGEF5

2.25e-052892IPR029212
DomainTis11B_N

ZFP36L1 ZFP36L2

2.25e-052892IPR007635
DomainZnf_C2H2-like

ZNF469 ZNF527 ZNF672 ZNF497 ZNF608 KLF6 MZF1 ZNF559 ZNF423 ZFP64 KCMF1 ZNF407 ZNF324B ZNF467

2.28e-057968914IPR015880
DomainZnf_C2H2

ZNF469 ZNF527 ZNF672 ZNF497 ZNF608 KLF6 MZF1 ZNF559 ZNF423 ZFP64 KCMF1 ZNF407 ZNF324B ZNF467

2.58e-058058914IPR007087
DomainZnF_C2H2

ZNF469 ZNF527 ZNF672 ZNF497 ZNF608 KLF6 MZF1 ZNF559 ZNF423 ZFP64 KCMF1 ZNF407 ZNF324B ZNF467

2.69e-058088914SM00355
DomainCFC

CFC1 CFC1B

6.72e-053892PF09443
DomainCryptic/Cripto_CFC-dom

CFC1 CFC1B

6.72e-053892IPR019011
DomainLCE

LCE2D LCE2C LCE2B

6.78e-0517893PF14672
DomainLCE

LCE2D LCE2C LCE2B

6.78e-0517893IPR028205
Domainzf-C2H2

ZNF469 ZNF527 ZNF672 ZNF497 KLF6 MZF1 ZNF559 ZNF423 ZFP64 ZNF407 ZNF324B ZNF467

1.07e-046938912PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF469 ZNF527 ZNF672 ZNF497 KLF6 MZF1 ZNF559 ZNF423 ZFP64 ZNF407 ZNF324B ZNF467

1.09e-046948912IPR013087
DomainSPRR/LCE

LCE2D LCE2C LCE2B

3.14e-0428893IPR026075
Domain-

ZNF527 ZNF672 ZNF497 KLF6 MZF1 ZNF559 ZNF423 ZFP64 ZNF407 ZNF324B ZNF467

3.75e-0467989113.30.160.60
Domainzf-C2H2_6

ZNF527 ZNF672 ZNF497 ZNF423 ZFP64 ZNF324B ZNF467

7.53e-04314897PF13912
DomainPH_dom-spectrin-type

SPTBN5 PSD2

7.91e-049892IPR001605
DomainPH

SPTBN5 PLEKHG1 PSD2 ARHGEF5 PLEKHA7

4.78e-03229895PF00169
Pubmed

Tobacco smoke regulates the expression and activity of microsomal prostaglandin E synthase-1: role of prostacyclin and NADPH-oxidase.

NOX1 PTGES

6.92e-06292221737615
Pubmed

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.

ZFP36L1 ZFP36L2

6.92e-06292220622884
Pubmed

Interaction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase.

ABL1 GRIN2D

6.92e-06292210777567
Pubmed

The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

CFC1 CFC1B

6.92e-06292211174844
Pubmed

Characterization of DeltaN-Zfp36l2 mutant associated with arrest of early embryonic development and female infertility.

ZFP36L1 ZFP36L2

6.92e-06292222367205
Pubmed

Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene.

KLF6 ACVRL1

6.92e-06292223048070
Pubmed

Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.

CFC1 CFC1B

6.92e-06292211327798
Pubmed

Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.

CFC1 CFC1B

6.92e-06292211024280
Pubmed

ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner.

ZFP36L1 ZFP36L2

6.92e-06292229426877
Pubmed

ARE-binding protein ZFP36L1 interacts with CNOT1 to directly repress translation via a deadenylation-independent mechanism.

ZFP36L1 CNOT1

6.92e-06292232311426
Pubmed

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.

CFC1 CFC1B

6.92e-06292211062482
Pubmed

Rodent Lce gene clusters; new nomenclature, gene organization, and divergence of human and rodent genes.

LCE2D LCE2C LCE2B

9.78e-061692317410201
Pubmed

Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice.

ANGPTL4 ZNF407

2.07e-05392227624101
Pubmed

Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins.

ZFP36L1 ZFP36L2

2.07e-05392214604009
Pubmed

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.

CFC1 CFC1B

2.07e-05392216835440
Pubmed

The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis.

ZFP36L1 ZFP36L2

2.07e-05392230526691
Pubmed

The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic β-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression.

ZFP36L1 ZFP36L2

2.07e-05392227566829
Pubmed

ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts.

ZFP36L1 ZFP36L2

2.07e-05392234333017
Pubmed

Functional analysis of ZFP36 proteins in keratinocytes.

ZFP36L1 ZFP36L2

2.07e-05392227182009
Pubmed

The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses.

ZFP36L1 ZFP36L2

2.07e-05392236269839
Pubmed

The roles of TTP and BRF proteins in regulated mRNA decay.

ZFP36L1 ZFP36L2

2.07e-05392221278925
Pubmed

Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.

ZFP36L1 ZFP36L2

2.07e-05392215814898
Pubmed

The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat.

ZFP36L1 ZFP36L2

2.07e-0539221996120
Pubmed

Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation.

LCE2D LCE2C LCE2B

2.66e-052292315854049
Pubmed

Differentially expressed late constituents of the epidermal cornified envelope.

LCE2D LCE2C LCE2B

3.05e-052392311698679
Pubmed

Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.

ABL1 ANGPTL4

4.14e-05492237169211
Pubmed

Synergistic roles of tristetraprolin family members in myeloid cells in the control of inflammation.

ZFP36L1 ZFP36L2

4.14e-05492237903626
Pubmed

Multiple tristetraprolin sequence domains required to induce apoptosis and modulate responses to TNFalpha through distinct pathways.

ZFP36L1 ZFP36L2

4.14e-05492212082611
Pubmed

ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production.

ZFP36L1 ZFP36L2

4.14e-05492220166898
Pubmed

Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease.

ABL1 NCKAP1

4.14e-05492211418237
Pubmed

Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling.

ZFP36L1 ZFP36L2

4.14e-05492211796723
Pubmed

Cripto in tumors and embryo development.

CFC1 CFC1B

4.14e-05492211825688
Pubmed

STAT3 induces breast cancer growth via ANGPTL4, MMP13 and STC1 secretion by cancer associated fibroblasts.

ANGPTL4 STC1

4.14e-05492235042959
Pubmed

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.

ZFP36L1 ZFP36L2

4.14e-05492225106868
Pubmed

Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1.

CFC1 CFC1B

4.14e-0549229576836
Pubmed

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.

ZFP36L1 ZFP36L2

4.14e-05492227102483
Pubmed

Role of the EGF-CFC gene cripto in cell differentiation and embryo development.

CFC1 CFC1B

4.14e-05492211992720
Pubmed

Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis.

ANGPTL4 STC1

6.89e-05592236795484
Pubmed

Differential expression and functional analysis of the tristetraprolin family during early differentiation of 3T3-L1 preadipocytes.

ZFP36L1 ZFP36L2

6.89e-05592222701344
Pubmed

Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins.

ZFP36L1 ZFP36L2

6.89e-05592238157296
Pubmed

Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase.

ZFP36L1 ZFP36L2

6.89e-05592224733888
Pubmed

Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism.

ZFP36L1 ZFP36L2

6.89e-05592226952984
Pubmed

A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.

CFC1 CFC1B

6.89e-0559229053319
Pubmed

Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.

CFC1 CFC1B

6.89e-05592225224222
Pubmed

Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b.

ZFP36L1 ZFP36L2

6.89e-05592215467755
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TGFB1I1 ZFP36L1 ZFP36L2 JADE3 KCMF1 AP1G2 TNKS SSH2 DOCK6 KANK2 CNOT1

9.41e-051038921126673895
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PLEKHG1 ESYT2 ABL1 NCKAP1 ZFP36L1 ZFP36L2 ARHGEF5 SSH2 DOCK6 PLEKHA7

9.49e-05861921036931259
Pubmed

A role of the cryptic gene in the correct establishment of the left-right axis.

CFC1 CFC1B

1.03e-04692210574770
Pubmed

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.

CFC1 CFC1B

1.03e-04692212052855
Pubmed

Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1.

ZFP36L1 ZFP36L2

1.03e-04692228394372
Pubmed

GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.

CFC1 CFC1B

1.03e-04692217991893
Pubmed

Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis.

CACNA1B ABL1

1.03e-0469228756350
Pubmed

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.

CFC1 CFC1B

1.44e-04792210521397
Pubmed

Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.

CFC1 CFC1B

1.44e-04792219906859
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TGFB1I1 ZNF469 SPATA31E1 PPFIBP2 ARHGEF5 TNKS PLEKHA7

1.49e-0443092735044719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PPP1R26 CPTP PLEKHG1 ABL1 ZFP36L2 AP1G2 TOR4A GRIN2D ZNF324B DOCK6 TRIM7

1.63e-041105921135748872
Pubmed

Mouse histamine N-methyltransferase: cDNA cloning, expression, gene cloning and chromosomal localization.

CACNA1B ABL1

1.92e-04892211475331
Pubmed

Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.

CFC1 CFC1B

1.92e-04892221419113
Pubmed

Two nodal-responsive enhancers control left-right asymmetric expression of Nodal.

CFC1 CFC1B

1.92e-04892215736223
Pubmed

Left-right patterning of the mouse lateral plate requires nodal produced in the node.

CFC1 CFC1B

2.46e-04992212654299
Pubmed

Left-asymmetric expression of Galanin in the linear heart tube of the mouse embryo is independent of the nodal co-receptor gene cryptic.

CFC1 CFC1B

2.46e-04992218773496
Pubmed

Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo.

CFC1 CFC1B

3.07e-041092217913787
Pubmed

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway.

CFC1 CFC1B

3.75e-041192215475956
Pubmed

BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment.

CFC1 CFC1B

5.30e-041392218550712
Pubmed

Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.

NCKAP1 GRIN2D

6.17e-041492215749123
Pubmed

Genetic mapping of the mouse genes encoding the voltage-sensitive calcium channel subunits.

CACNA1B ABL1

6.17e-04149227490102
Pubmed

Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.

PDE3A ADRB1

6.17e-041492225852085
Pubmed

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry.

CFC1 CFC1B

6.17e-041492217210915
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1B CACNA2D4

7.11e-041592220188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1B CACNA2D4

7.11e-041592224453333
Pubmed

Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse.

CFC1 CFC1B

7.11e-041592212361961
Pubmed

Rab23 regulates Nodal signaling in vertebrate left-right patterning independently of the Hedgehog pathway.

CFC1 CFC1B

7.11e-041592224780629
Pubmed

Maternal Cripto is critical for proper development of the mouse placenta and the placental vasculature.

CFC1 CFC1B

7.11e-041592233730615
Pubmed

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells.

CFC1 CFC1B

7.11e-041592217360443
Pubmed

Man1, an inner nuclear membrane protein, regulates left-right axis formation by controlling nodal signaling in a node-independent manner.

CFC1 CFC1B

9.17e-041792218697220
Pubmed

Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate.

CFC1 CFC1B

9.17e-041792219716815
Pubmed

Gut endoderm is involved in the transfer of left-right asymmetry from the node to the lateral plate mesoderm in the mouse embryo.

CFC1 CFC1B

9.17e-041792222627279
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRIM67 NCKAP1 TBL1Y DCHS1 TNKS SSH2 GRIN2D KANK2 CNOT1

1.03e-0396392928671696
Pubmed

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.

CFC1 CFC1B

1.03e-031892217936261
Pubmed

Gene structure and chromosomal localization of the mouse NMDA receptor channel subunits.

ABL1 GRIN2D

1.03e-03189229011744
Pubmed

Tcf3: a transcriptional regulator of axis induction in the early embryo.

CFC1 CFC1B

1.03e-031892214668413
Pubmed

Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis.

CFC1 CFC1B

1.03e-031892220346354
Pubmed

Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women.

CYP4B1 ZNF407

1.15e-031992222675492
Pubmed

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic.

CFC1 CFC1B

1.15e-031992228126904
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

PLEKHG1 NCKAP1 ZFP36L2 DOCK6 PLEKHA7 CNOT1

1.21e-0344692624255178
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node.

CFC1 CFC1B

1.27e-032092211517919
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node.

CFC1 CFC1B

1.27e-032092211440720
Pubmed

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism.

SCO2 ESYT2 KCMF1

1.32e-038192332060556
Pubmed

Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.

CFC1 CFC1B

1.41e-032192216291790
Pubmed

Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo.

CFC1 CFC1B

1.54e-032292218241853
Pubmed

RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons.

KANK2 STC1

1.54e-032292233903225
Pubmed

Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.

ZNF608 SYTL5

1.69e-032392220932654
Pubmed

Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.

CFC1 CFC1B

1.69e-032392214623818
Pubmed

Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse.

CFC1 CFC1B

1.84e-032492218171685
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

SPTBN5 ASB16 KCMF1 ACVRL1 CNOT1

1.90e-0333192519490893
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PLEKHG1 ESYT2 NCKAP1 JADE3 CPLANE1 PLEKHA7 KANK2 CNOT1

1.93e-0385392828718761
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

SPTBN5 CACNA1B NCKAP1 DOCK6 KANK2 EZHIP

2.07e-0349692631343991
Pubmed

Endogenous Nodal signaling regulates germ cell potency during mammalian testis development.

CFC1 CFC1B

2.16e-032692223034635
Pubmed

The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo.

CFC1 CFC1B

2.16e-032692223651855
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

CFC1 CFC1B CPLANE1

2.41e-0310092325807483
CytobandEnsembl 112 genes in cytogenetic band chr9q34

PPP1R26 CACNA1B ABL1 PTGES TOR4A PNPLA7

5.14e-05325926chr9q34
Cytoband9q34.3

PPP1R26 PTGES TOR4A PNPLA7

6.42e-051069249q34.3
Cytoband19p13.2

ADAMTS10 ZNF559 LYL1 DOCK6 KANK2

1.02e-0422992519p13.2
CytobandEnsembl 112 genes in cytogenetic band chr19p13

ADAMTS10 ZNF559 ANGPTL4 LYL1 DOCK6 KANK2 CYP4F11

1.13e-03797927chr19p13
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF469 ZNF527 ZNF672 ZNF497 ZNF608 KLF6 MZF1 ZNF559 ZNF423 ZFP64 ZNF407 ZNF324B ZNF467

7.54e-07718621328
GeneFamilyLate cornified envelope proteins

LCE2D LCE2C LCE2B

3.02e-0518623627
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG1 ARHGEF35 ARHGEF5

1.51e-0366623722
GeneFamilyRing finger proteins

RNF151 TRIM67 ZFP36L1 ZFP36L2 TRIM7

2.51e-0327562558
GeneFamilySterile alpha motif domain containing

PPFIBP2 TNKS KIF24

3.43e-0388623760
GeneFamilyCalcium voltage-gated channel subunits

CACNA1B CACNA2D4

3.57e-0326622253
GeneFamilyCytochrome P450 family 4

CYP4B1 CYP4F11

6.76e-03366221003
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 PSD2 TRIM67 SLITRK5 KLHDC7A STC1

4.11e-071379264dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 PSD2 TRIM67 SLITRK5 KLHDC7A STC1

4.11e-07137926c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

TGFB1I1 HHIP PSD2 ZNF608 CARNS1 CYP4F11

1.72e-06175926ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

TGFB1I1 HHIP PSD2 ZNF608 CARNS1 CYP4F11

1.72e-06175926eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZFP36L1 ZFP36L2 ZNF423 ANGPTL4 PLEKHA7 CYP4F11

2.52e-061879262b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TGFB1I1 ARHGEF5 ANGPTL4 PTGES DOCK6 KANK2

2.68e-06189926ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCellproximal-Hematologic-Platelet/Megakaryocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPTBN5 ZNF469 ZNF527 FLYWCH1 PTGES PLEKHA7

2.94e-06192926522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCellproximal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPTBN5 ZNF469 ZNF527 FLYWCH1 PTGES PLEKHA7

2.94e-06192926f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCellproximal-Hematologic-Platelet/Megakaryocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPTBN5 ZNF469 ZNF527 FLYWCH1 PTGES PLEKHA7

2.94e-0619292657899a905ca3e336bb7f31edc6418a2546b9891a
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ADRB1 ZNF608 ZNF423 ACVRL1 DOCK6

3.12e-0619492658f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ADRB1 ZNF608 ZNF423 ACVRL1 DOCK6

3.12e-06194926bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NCKAP1 ANGPTL4 DCHS1 ACVRL1 DOCK6 STC1

3.51e-061989262630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NCKAP1 ANGPTL4 DCHS1 ACVRL1 DOCK6 STC1

3.51e-061989261e83bec16dcd60460422625f89952ff506d6be51
ToppCell10x3'2.3-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NCKAP1 ANGPTL4 DCHS1 ACVRL1 DOCK6 STC1

3.61e-0619992641f046646fff65b7e51b63d3204f76ef32054781
ToppCell10x3'2.3-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NCKAP1 ANGPTL4 DCHS1 ACVRL1 DOCK6 STC1

3.61e-06199926ef7f7f7c861827574b120f48cf4052c563929081
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

REXO5 ZNF497 SYTL5 PRRT3 GRIN2D

6.95e-06128925082b3dc312b033c9b21cf73499009a1dc049ee2b
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8|TCGA-Bladder / Sample_Type by Project: Shred V9

CYP4B1 PPFIBP2 TSGA10 KLHDC7A PLEKHA7

1.45e-0514992589705865e94360c1288ee98c5a6b381f3c6242b3
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4B1 GPT CFC1 CARNS1 HS3ST1

2.66e-051699250cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4B1 GPT CFC1 CARNS1 HS3ST1

2.66e-051699256937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRB1 KLF6 ZFP36L1 ZFP36L2 SSH2

2.98e-05173925869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF35 SYTL5 PTGES HS3ST1 KIF25-AS1

2.98e-05173925176b956e71d98e8275d698b39437fc326e5fe449
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRB1 KLF6 ZFP36L1 ZFP36L2 SSH2

2.98e-051739250672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRB1 KLF6 ZFP36L1 ZFP36L2 SSH2

2.98e-05173925870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRB1 KLF6 ZFP36L1 ZFP36L2 SSH2

3.14e-051759251ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

TGFB1I1 ADAMTS10 HHIP ZNF469 DCHS1

3.41e-05178925142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB1I1 HHIP PTGES KANK2 LCE2B

3.89e-051839256b5eef96b28911c752a8b6c0975918c4572cec38
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 ZPLD1 DOCK6 KANK2 STC1

3.99e-0518492594748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 ZPLD1 DOCK6 KANK2 STC1

3.99e-05184925819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

PLEKHG1 ZNF423 DCHS1 ACVRL1 DOCK6

4.10e-0518592507f9f38f0739d7c830641723a38385550ac1ac92
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A NCKAP1 KLF6 ZFP36L1 KCMF1

4.10e-05185925eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ADAMTS10 ZFP36L1 ZFP36L2 ZNF423 LYL1

4.42e-05188925c90669b51e1902fe7726555290c91c92a911df83
ToppCellEntopeduncular-Endothelial|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TGFB1I1 ZFP36L1 ANGPTL4 ACVRL1 KANK2

4.42e-0518892594774652fd42bad5012356672ffac8b6d2c22d37
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TGFB1I1 CACNA1B PLEKHG1 HHIP STC1

4.54e-051899250abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PSD2 ZFP36L1 ZNF423 ANGPTL4 PLEKHA7

4.89e-05192925f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

4.89e-051929250aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A ADRB1 NCKAP1 CYP4B1 ACVRL1

4.89e-051929254bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PSD2 ZFP36L1 ZNF423 ANGPTL4 PLEKHA7

4.89e-05192925705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PSD2 ZFP36L1 ZFP36L2 ANGPTL4 PLEKHA7

5.01e-05193925b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ZNF608 ZNF423 ACVRL1 DOCK6

5.01e-051939256e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ZNF608 ZNF423 ACVRL1 DOCK6

5.01e-05193925af5108260783e69a7d67896c5bf64f862525926d
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PSD2 ZFP36L1 ZFP36L2 ANGPTL4 PLEKHA7

5.01e-0519392540edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCelldroplet-Lung-nan-21m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.01e-051939254893b922e129711d5886bd4f3ee106e9e7065971
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 PDE3A ZNF423 ACVRL1 LYL1

5.01e-051939250b328f725f6feba263783eaca60c142e80df90f3
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.01e-05193925ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCelldroplet-Lung-nan-21m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.01e-05193925ae35c5757a88b02f8b9f94a0af4c3396ca828cc3
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.14e-05194925e13923860a64ba9cf32df53c9f0cf4e7c321881d
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A ADRB1 NCKAP1 CYP4B1 ACVRL1

5.14e-05194925f159ef8541d75a4e98468947f231bb463bec922c
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.14e-0519492543f92b0533e26633dc94cce554045d641ef8fd76
ToppCelldroplet-Lung-1m-Endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.14e-05194925b1a25e3b36e7b7e558ef95ec22a3bdcbceae821f
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MZF1 ZNF559 ARHGEF5 PRRT3 KANK2

5.14e-051949255031f324628ff12a33e84cc52157be4786e0961d
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

PLEKHG1 NCKAP1 ZNF423 DOCK6 STC1

5.14e-051949259591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ZNF608 ZNF423 ACVRL1 DOCK6

5.14e-051949250b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.14e-051949251d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.14e-05194925fc3f81b5bdc544a69c355e482f002643e029a7b0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE3A TRIM67 ZNF608 SYTL5 GRIN2D

5.14e-051949254f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.14e-05194925b49c19c33ad2e391d9367a4a2695b2fe87dd8a08
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.14e-0519492586508dd9b9d345b6624d185048cc92b81dd11c2a
ToppCelldroplet-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 ADRB1 CYP4B1 ACVRL1 HS3ST1

5.14e-05194925fd4548db0f12170b636186e6af90666f7e26c0ad
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 PDE3A ADRB1 NCKAP1 CYP4B1

5.26e-051959257f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellPosterior_cortex-Endothelial|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TGFB1I1 ARHGEF5 ANGPTL4 DOCK6 KANK2

5.26e-05195925988e3449691cc228cb55e5e30355136c97b12262
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3A ZNF423 ANGPTL4 DCHS1 ACVRL1

5.39e-05196925915e4a7422058be246b54760df31e8a607310625
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

PLEKHG1 ZNF608 ZNF423 ACVRL1 DOCK6

5.52e-051979257e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.52e-0519792581718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYTL5 CYP4B1 UNC5CL AP1G2 PLEKHA7

5.52e-051979253d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.66e-05198925a1ccbf0e653b2dd665c2254920eb9b37243cc0bd
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.66e-051989251d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG1 ADRB1 ANGPTL4 ACVRL1 STC1

5.66e-051989255eedcc20e35adbabe268a93b748ee4566b3ffb66
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB1I1 PLEKHG1 DCHS1 ACVRL1 STC1

5.66e-051989250c8ec287500c58938ecc0dbbbc5f6c7a48733fc6
ToppCellBronchial-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.79e-0519992536a230b80096455df26c2e2c8c05fd6b231508c5
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 ADRB1 ZNF423 ACVRL1 DOCK6

5.79e-05199925d58edc5f74970bb26d844746184e4bae7c494d6b
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZFP64 ANGPTL4 ZNF324B ACVRL1 DOCK6

5.79e-051999256f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NCKAP1 ANGPTL4 ACVRL1 DOCK6 STC1

5.79e-051999251c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYTL5 CYP4B1 UNC5CL TSGA10 AP1G2

5.79e-05199925a270630626df614f8605abddb7dee7c4d74f6149
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZFP64 ANGPTL4 ZNF324B ACVRL1 DOCK6

5.79e-051999251aa99d21bf61b86df4a966dc47634044430aa39f
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGFB1I1 PLEKHG1 HHIP ANGPTL4 ACVRL1

5.79e-05199925079931e7196719f22a89cfad82f452ec67219ee5
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABL1 ZFP36L1 CYP4B1 PTGES KANK2

5.93e-05200925db6281b5d4032116310db379d9175d790994c99c
ToppCell10x5'v1-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANGPTL4 DCHS1 ACVRL1 DOCK6 STC1

5.93e-052009252488aa12970a43a5af352e2c36c73884d73a1cc5
ToppCellNeuronal-Inhibitory|Neuronal / cells hierarchy compared to all cells using T-Statistic

PDE3A TRIM67 ZNF608 SYTL5 GRIN2D

5.93e-052009259ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCell10x5'v1-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANGPTL4 DCHS1 ACVRL1 DOCK6 STC1

5.93e-0520092577ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TGFB1I1 HHIP ESYT2 CPLANE1 KANK2

5.93e-05200925dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell10x5'v1-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ANGPTL4 DCHS1 ACVRL1 DOCK6 STC1

5.93e-05200925e786544cf6f891550c4be55ebb4928c92297b504
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDE3A NCKAP1 ACVRL1 DOCK6 STC1

5.93e-05200925b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

TGFB1I1 HHIP ESYT2 PDE3A KANK2

5.93e-052009258bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LDHD ZNF469 KIAA1328 SLITRK5

2.14e-04142924f720f13b339589fa924a42e89393e5db0b26300b
ToppCellMS-CD4-CD8_1|MS / Condition, Cell_class and T cell subcluster

ABL1 ASB16 PNPLA7 KLHDC7A

2.64e-041509247dc95c58b98d8c4c6c49fb1a03ec6ac24fb41f54
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD8-Trm_gut_CD8|bone_marrow / Manually curated celltypes from each tissue

PLEKHG1 ADRB1 KLF6 ZFP36L2

2.71e-041519245eebdc7ad6af3cc0263e4d8c3516818305ac38f2
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PSD2 TRIM67 ZNF608 GRIN2D

2.99e-04155924105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

PPP1R26 PSD2 ASB16 GRIN2D

3.14e-04157924c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Neutrophil|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LDHD REXO5 ZNF497 TBL1Y

3.37e-041609247af3fbe555ff2eb1272381411617646e9e8c0440
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

KLF6 ZFP36L1 ZFP36L2 LYL1

3.54e-0416292491ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCellLPS-IL1RA-Unknown-Endothelial-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A ADRB1 TDP1 LYL1

3.62e-041639246b11a3ada8725670d0489f404c8c2175ad3904e9
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TGFB1I1 ADAMTS10 PDE3A DCHS1

3.62e-041639248f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ZNF423 GRIN2D TRIM7

3.62e-04163924bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ZNF423 GRIN2D TRIM7

3.62e-041639248e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

PDE3A DCHS1 HS3ST1 KANK2

3.79e-041659245fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

PDE3A DCHS1 HS3ST1 KANK2

3.79e-0416592493d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-7|TCGA-Kidney / Sample_Type by Project: Shred V9

LNP1 ZNF497 SSH2 HS3ST1

3.88e-04166924b545de32578047c9ca422354b8992f2d9c9e1cc7
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PSD2 TRIM67 SYTL5 GRIN2D

3.97e-041679249a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCellP28|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADRB1 CYP4B1 ACVRL1 HS3ST1

4.06e-041689244ee59a6147bbe7e4a03cc2d6fe9d6c10b18a3a06
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE3A NOX1 ACVRL1 HS3ST1

4.06e-0416892432e4d82efaccf336d347e4063253c3635a3ec672
DrugMethylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; PC3; HT_HG-U133A

SPTBN5 ZFP36L1 ZFP36L2 ZNF423 TSGA10 FRS3 ACVRL1 CPLANE1 ZNF467

1.06e-071979294618_UP
DrugBenfotiamine [22457-89-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A

TGFB1I1 NOX1 TBL1Y MZF1 IGHMBP2 GPT TOR4A STC1

1.36e-061979283837_DN
Diseasedouble outlet right ventricle (implicated_via_orthology)

CFC1 CFC1B

2.40e-053842DOID:6406 (implicated_via_orthology)
Diseasesystolic blood pressure, alcohol drinking

PLEKHG1 PDE3A ADRB1 TNKS PLEKHA7

3.33e-05128845EFO_0004329, EFO_0006335
Diseasedextro-looped transposition of the great arteries (implicated_via_orthology)

CFC1 CFC1B

4.79e-054842DOID:0060770 (implicated_via_orthology)
Diseaseright atrial isomerism (implicated_via_orthology)

CFC1 CFC1B

4.79e-054842DOID:0060856 (implicated_via_orthology)
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

PDE3A ADRB1 ANGPTL4 PCIF1 DOCK6 KANK2

2.85e-04315846EFO_0004574, EFO_0004612
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

PDE3A ADRB1 ANGPTL4 PCIF1 DOCK6 KANK2

2.85e-04315846EFO_0004612, EFO_0008591
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

PDE3A ADRB1 ZFP36L1 ANGPTL4 PCIF1 DOCK6

3.15e-04321846EFO_0004612, EFO_0004639
Diseasediastolic blood pressure, alcohol drinking

PLEKHG1 ADRB1 TNKS PLEKHA7

3.66e-04118844EFO_0004329, EFO_0006336
Diseasevisceral heterotaxy (is_implicated_in)

CFC1 CFC1B

5.19e-0412842DOID:0050545 (is_implicated_in)
Diseasefree cholesterol to total lipids in very large HDL percentage

ANGPTL4 PCIF1 DOCK6

5.25e-0455843EFO_0022288
Diseasefree cholesterol in HDL measurement

ANGPTL4 PCIF1 DOCK6

7.11e-0461843EFO_0022264
Diseasephospholipids in HDL measurement

ANGPTL4 PCIF1 DOCK6

7.11e-0461843EFO_0022293
Diseasetotal lipids in HDL measurement

ANGPTL4 PCIF1 DOCK6

7.81e-0463843EFO_0022307
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ANGPTL4 PCIF1 DOCK6 KANK2

9.72e-04153844EFO_0004611, EFO_0020946
Diseasephospholipids in large HDL measurement

ANGPTL4 PCIF1 DOCK6

1.20e-0373843EFO_0022190
Diseasetotal lipids in large HDL

ANGPTL4 PCIF1 DOCK6

1.25e-0374843EFO_0022189
Diseasehigh density lipoprotein particle size measurement

ADRB1 ANGPTL4 PCIF1 DOCK6

1.43e-03170844EFO_0008592
Diseasecholesterol in large HDL measurement

ANGPTL4 PCIF1 DOCK6

1.56e-0380843EFO_0021900
Diseasepulmonary hypertension (biomarker_via_orthology)

PDE3A NOX1 ACVRL1

1.56e-0380843DOID:6432 (biomarker_via_orthology)
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ADRB1 ZFP36L1 ANGPTL4 PCIF1 DOCK6

1.76e-03303845EFO_0004612, EFO_0020945
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

ADRB1 ZFP36L1 ANGPTL4 PCIF1 DOCK6

1.86e-03307845EFO_0004612, EFO_0020946
Diseasecholesteryl ester measurement, high density lipoprotein cholesterol measurement

PDE3A ADRB1 ANGPTL4 PCIF1 DOCK6

2.00e-03312845EFO_0004612, EFO_0010351
Diseasewaist-hip ratio

ADAMTS10 HHIP ADRB1 KLF6 ZNF423 KIAA1328 ZNF407 DOCK6 TRIM7 STC1

2.51e-0312268410EFO_0004343
Diseaselipid measurement, high density lipoprotein cholesterol measurement

PDE3A ADRB1 ANGPTL4 PCIF1 DOCK6

2.55e-03330845EFO_0004529, EFO_0004612
Diseasemean arterial pressure, alcohol drinking

PLEKHG1 ADRB1 PLEKHA7

2.79e-0398843EFO_0004329, EFO_0006340

Protein segments in the cluster

PeptideGeneStartEntry
LHRALGQARDHCRPR

GPT

221

P24298
RHATHGDRPRASGCL

ADRB1

401

P08588
DAALSSHRHPGCAQR

ESYT2

6

A0FGR8
HNVSRLHRLPRDCQE

ANGPTL4

176

Q9BY76
GRARSREEENEHHGP

ARHGEF5

391

Q12774
GRARSREEENEHHGP

ARHGEF35

391

A5YM69
RASFRDGDPVHRHRQ

AP1G2

36

O75843
RPHRSCRDPAVHQAL

ASB16

51

Q96NS5
EDAPQCHEHFSRITR

CARNS1

566

A5YM72
RHPQEHRGCGNLHRE

ACVRL1

61

P37023
HDQRRSECGALEHGA

CFC1B

116

P0CG36
RAHRHQDPSKECAGA

CACNA1B

936

Q00975
HDQRRSECGALEHGA

CFC1

116

P0CG37
RHPHLDTACGVRDEK

ADAMTS10

186

Q9H324
DDRDSHCRRPKFEGH

NOX1

251

Q9Y5S8
RLRAHDPDQGSHGRL

DCHS1

706

Q96JQ0
PRRHSHEDQEFRCRS

LNP1

66

A1A4G5
GHCHAPDEQGLEARR

FLYWCH1

171

Q4VC44
RHSDRQDCRSPHEVF

EZHIP

96

Q86X51
QAPTAGRDCHHRADP

PDE3A

21

Q14432
GRDCHHRADPASPRD

PDE3A

26

Q14432
RDPINHRRAALDHSC

KIF24

896

Q5T7B8
GPRLRCLHHDQGLTE

KIF25-AS1

26

Q9Y6Z4
CGHRLAADRVHDSHP

KIAA1328

306

Q86T90
ACDRARVFLHSDEHP

PNPLA7

396

Q6ZV29
NPHCLHRRPADESNL

PPFIBP2

696

Q8ND30
HELCPEERHHIGDRS

NCKAP1

581

Q9Y2A7
EERHHIGDRSLSLCN

NCKAP1

586

Q9Y2A7
DRLEHLRRQCGPHVS

PCIF1

336

Q9H4Z3
HRSLEAAQDARGHCP

DOCK6

816

Q96HP0
ENAREPRKNSPHCHE

CPLANE1

2126

Q9H799
RRRPDSCHAFHPEEN

CACNA2D4

1091

Q7Z3S7
PASEDDHRRGRHCLQ

FRS3

196

O43559
PDGQRFRRACHLVHD

CYP4F11

251

Q9HBI6
LVDLERRSHHPESGC

CPTP

91

Q5TA50
REQHGRDESVHRCEP

LDHD

51

Q86WU2
HRDLAARNCLVGENH

ABL1

361

P00519
RRPSHCELDLAEGHQ

LYL1

131

P12980
ACRSDAHPELVRRHL

KANK2

631

Q63ZY3
NQARPHCRLVALDGH

KLHDC7A

576

Q5VTJ3
HRAPRDLDESSGVRH

KCMF1

136

Q9P0J7
FHRRRHQSPDCCESE

LCE2B

81

O14633
FHRRRHQSPDCCESE

LCE2C

81

Q5TA81
FHRRRHQSPDCCESE

LCE2D

81

Q5TA82
PHGRRFLRACQVAHD

CYP4B1

241

P13584
QGDFHLLDHRGRARC

SCO2

101

O43819
RADSHRNSDVRHAPA

PRRT3

66

Q5FWE3
RENPPHDSRRDCHGK

JADE3

796

Q92613
GRDRCLHESKGRAHP

HS3ST1

261

O14792
HRAVRALCDHTAARP

RUSC1

846

Q9BVN2
HCHRNLGLIFDRGDP

SYTL5

66

Q8TDW5
RCVPSLHHRALDAEE

TIMM10B

31

Q9Y5J6
DPAERARHNCYRELH

RNF151

151

Q2KHN1
NPERHDRRLNHFRVC

FAM183A

101

A6NL82
TRDCPHRGHDDIVNF

PLEKHA7

321

Q6IQ23
HHCPVKNRGIRDRDS

SPATA31E1

1386

Q6ZUB1
ERAAQRGHRAEGCHD

PPP1R26

66

Q5T8A7
RGHRAEGCHDARPAA

PPP1R26

71

Q5T8A7
ADHSQGRAEPGHERR

PPP1R26

621

Q5T8A7
SDPDVERCLRAHRND

PTGES

61

O14684
AHGLHDPGRCAVDRH

HHIP

426

Q96QV1
CQRSPEAAHGLRHRQ

SPTBN5

2431

Q9NRC6
HCAQTHPRADFNRRR

STC1

201

P52823
EECARAGFPRAHRHK

CLUH

586

O75153
VNRHGPEADRHLLRC

CNOT1

36

A5YKK6
RTENHGAPACHRLKE

TDP1

126

Q9NUW8
PRCHFIHNAEERRAL

ZFP36L1

171

Q07352
QCHRSASLDHRGLRG

TRIM67

161

Q6ZTA4
TDLALNGRHGDSHCR

ZPLD1

66

Q8TCW7
HRRVHTGARPHACRD

ZNF497

236

Q6ZNH5
VCDRAREHREHAVLP

TRIM7

151

Q9C029
RLRQEQEHHGAAPTC

SSH2

876

Q76I76
QPGEEERRESHHLRS

SLITRK5

816

O94991
TAELAEHRCHPVERG

PSD2

671

Q9BQI7
LPEIHGCGERARAHA

IGHMBP2

926

P38935
QCPDRLGHDATEDAR

REXO5

356

Q96IC2
NCRDLEGRHSTPLHF

TNKS

676

O95271
LRHRRSHQGERPHAC

ZNF672

271

Q499Z4
RPGAHASRDECRIHL

UNC5CL

211

Q8IV45
LRHCIREGGHDVPSN

TBL1Y

221

Q9BQ87
ARGRCAPDHFQEDHL

ZNF469

3601

Q96JG9
AHHRSPDRGLDRSLE

TSGA10

676

Q9BZW7
ARHHCPEARAAQDCR

TOR4A

226

Q9NXH8
ERERDRHSPFGQRHL

ZNF608

1446

Q9ULD9
EHEGRPLCENHFHAR

TGFB1I1

386

O43294
HRSSRCESHQDLLPD

PLEKHG1

1211

Q9ULL1
DLTDHRAHRCPGDGD

ZNF423

81

Q2M1K9
HRHLCPVTLDGERSA

ZNF407

1246

Q9C0G0
RCHFIHNADERRPAP

ZFP36L2

211

P47974
RHLRSHSAERPFECE

ZNF559

426

Q9BR84
HCAFQGRDRADLLEH

ZFP64

471

Q9NTW7
HQRSHRGERPFPCSE

ZNF467

206

Q7Z7K2
CGRAFRERPALLHHQ

ZNF324B

486

Q6AW86
NRHHRIHTGERPFEC

ZNF527

486

Q8NB42
ASPDGRRRVHRCHFN

KLF6

191

Q99612
HRRVHSGERPFACAE

MZF1

531

P28698
LPELGHDCRAQNRTH

GRIN2D

341

O15399