Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoAplasia/Hypoplasia of the cerebellar vermis

PPP1R21 PCYT1A RAPSN WASHC5 NSD1 MACF1 MME CDC42BPB SEMA3E

5.14e-05369269HP:0006817
HumanPhenoCerebellar vermis hypoplasia

PPP1R21 PCYT1A RAPSN WASHC5 NSD1 MACF1 MME CDC42BPB SEMA3E

5.14e-05369269HP:0001320
HumanPhenoAbnormal cerebellar vermis morphology

PPP1R21 PCYT1A RAPSN WASHC5 NSD1 MACF1 MME CDC42BPB SEMA3E

5.72e-05374269HP:0002334
DomainBTB

IBTK KLHL10 ZBTB43 ZBTB1 KLHL26

1.41e-04131715PF00651
DomainCNMP_BINDING_1

KCNH7 RAPGEF4 PNPLA7

2.41e-0432713PS00888
DomainCNMP_BINDING_2

KCNH7 RAPGEF4 PNPLA7

2.41e-0432713PS00889
DomaincNMP

KCNH7 RAPGEF4 PNPLA7

2.89e-0434713SM00100
DomaincNMP_binding

KCNH7 RAPGEF4 PNPLA7

2.89e-0434713PF00027
DomaincNMP-bd_dom

KCNH7 RAPGEF4 PNPLA7

3.16e-0435713IPR000595
DomainCNMP_BINDING_3

KCNH7 RAPGEF4 PNPLA7

3.16e-0435713PS50042
DomainBTB

IBTK KLHL10 ZBTB43 ZBTB1 KLHL26

3.58e-04160715PS50097
DomainPkinase_C

AKT1 PRKCQ CDC42BPB

3.73e-0437713IPR017892
DomaincNMP-bd-like

KCNH7 RAPGEF4 PNPLA7

4.04e-0438713IPR018490
DomainPkinase_C

AKT1 PRKCQ CDC42BPB

5.43e-0442713PF00433
DomainBTB

IBTK KLHL10 ZBTB43 ZBTB1 KLHL26

6.12e-04180715SM00225
DomainBTB/POZ_dom

IBTK KLHL10 ZBTB43 ZBTB1 KLHL26

6.93e-04185715IPR000210
DomainSKP1/BTB/POZ

IBTK KLHL10 ZBTB43 ZBTB1 KLHL26

7.63e-04189715IPR011333
Domain-

KCNH7 RAPGEF4 PNPLA7

8.05e-04487132.60.120.10
DomainRmlC-like_jellyroll

KCNH7 RAPGEF4 PNPLA7

9.62e-0451713IPR014710
DomainAGC-kinase_C

AKT1 PRKCQ CDC42BPB

1.26e-0356713IPR000961
DomainAGC_KINASE_CTER

AKT1 PRKCQ CDC42BPB

1.26e-0356713PS51285
DomainS_TK_X

AKT1 PRKCQ CDC42BPB

1.26e-0356713SM00133
DomainGal_Oxase/kelch_b-propeller

KLHL10 LCMT2 KLHL26

1.47e-0359713IPR011043
DomainDAG/PE-bd

PRKCQ CDC42BPB

2.86e-0321712IPR020454
DomainLIPASE_SER

PNLIP PAFAH2

4.37e-0326712PS00120
Domain-

KLHL10 KLHL26

4.70e-03277122.130.10.80
DomainRICIN

GALNT3 LY75

5.05e-0328712SM00458
DomainRICIN_B_LECTIN

GALNT3 LY75

5.05e-0328712PS50231
DomainRicin_B_lectin

GALNT3 LY75

5.79e-0330712IPR000772
DomainGal_Oxidase_b-propeller

KLHL10 KLHL26

7.39e-0334712IPR015916
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

MYO1E AKT1 MME CTSL

8.68e-0572464M39403
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

MYO1E AKT1 MME CTSL

9.16e-0573464MM15906
Pubmed

Protein kinase C-theta regulates KIT expression and proliferation in gastrointestinal stromal tumors.

PRKCQ KIT

4.35e-06273218521081
Pubmed

The heparanase system and tumor metastasis: is heparanase the seed and soil?

HPSE2 CTSL

4.35e-06273221308479
Pubmed

KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway.

AKT1 KIT

4.35e-06273217546049
Pubmed

Effect of disruption of Akt-1 of lin(-)c-kit(+) stem cells on myocardial performance in infarcted heart.

AKT1 KIT

4.35e-06273220410290
Pubmed

Evaluation of Akt and RICTOR Expression Levels in Astrocytomas of All Grades.

AKT1 RICTOR

4.35e-06273227789731
Pubmed

Sustained Mutant KIT Activation in the Golgi Complex Is Mediated by PKC-θ in Gastrointestinal Stromal Tumors.

PRKCQ KIT

4.35e-06273227440273
Pubmed

Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology.

AKT1 RICTOR

4.35e-06273223852728
Pubmed

mTOR-rictor is the Ser473 kinase for AKT1 in mouse one-cell stage embryos.

AKT1 RICTOR

4.35e-06273222057724
Pubmed

Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells.

AKT1 PRKCQ

4.35e-06273211410591
Pubmed

Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).

AKT1 RICTOR

1.30e-05373228986255
Pubmed

Omega-3 fatty acid epoxides produced by PAF-AH2 in mast cells regulate pulmonary vascular remodeling.

PAFAH2 KIT

1.30e-05373235641514
Pubmed

An immunohistochemical panel consisting of EZH2, C-KIT, and CD205 is useful for distinguishing thymic squamous cell carcinoma from type B3 thymoma.

LY75 KIT

1.30e-05373229487009
Pubmed

Gastrointestinal stromal tumors (GISTs): CD117, DOG-1 and PKCθ expression. Is there any advantage in using several markers?

PRKCQ KIT

1.30e-05373222197035
Pubmed

mTORC2 signaling promotes skeletal growth and bone formation in mice.

AKT1 RICTOR

1.30e-05373225196701
Pubmed

Role for the adaptor protein Grb10 in the activation of Akt.

AKT1 KIT

1.30e-05373211809791
Pubmed

RICTOR involvement in the PI3K/AKT pathway regulation in melanocytes and melanoma.

AKT1 RICTOR

1.30e-05373226356562
Pubmed

Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis.

CCRL2 KIT

1.30e-05373218794339
Pubmed

Inhibition of Gsk3β activity improves β-cell function in c-KitWv/+ male mice.

AKT1 KIT

1.30e-05373222249311
Pubmed

Stem cell factor (SCF) protects osteoblasts from oxidative stress through activating c-Kit-Akt signaling.

AKT1 KIT

1.30e-05373225449280
Pubmed

Tight regulation of a timed nuclear import wave of EKLF by PKCθ and FOE during Pro-E to Baso-E transition.

ANKRD17 PRKCQ

1.30e-05373224576425
Pubmed

Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival.

AKT1 RICTOR

1.30e-05373222384145
Pubmed

Altered SDF-1-mediated differentiation of bone marrow-derived endothelial progenitor cells in diabetes mellitus.

AKT1 KIT

1.30e-05373220196780
Pubmed

AKT2 is essential to maintain podocyte viability and function during chronic kidney disease.

AKT1 RICTOR

1.30e-05373224056770
Pubmed

MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses.

RAPSN MACF1

1.30e-05373230842214
Pubmed

Increased Rac activity is required for the progression of T-lymphomas induced by Pten-deficiency.

TIAM1 AKT1

1.30e-05373217521720
Pubmed

Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.

PRKCQ MME

1.30e-05373223838604
Pubmed

Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta.

AKT1 PRKCQ

1.30e-05373214985363
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

IBTK MACF1 AKT1 RICTOR CDC42BPB

2.26e-0516073531678930
Pubmed

Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.

AKT1 KIT

2.60e-05473227468693
Pubmed

Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice.

AKT1 RICTOR

2.60e-05473224662050
Pubmed

Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1).

TIAM1 AKT1

2.60e-05473220360004
Pubmed

Protein kinase C-θ inhibits inducible regulatory T cell differentiation via an AKT-Foxo1/3a-dependent pathway.

AKT1 PRKCQ

2.60e-05473222539794
Pubmed

Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1.

AKT1 ZRANB1

2.60e-05473229748601
Pubmed

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.

AKT1 RICTOR

2.60e-05473216603397
Pubmed

A20 interacts with mTORC2 to inhibit the mTORC2/Akt/Rac1 signaling axis in hepatocellular carcinoma cells.

AKT1 RICTOR

2.60e-05473236411371
Pubmed

Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway.

AKT1 RICTOR

2.60e-05473228699701
Pubmed

mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.

AKT1 RICTOR

2.60e-05473223092880
Pubmed

Casein kinase 2 dependent phosphorylation of neprilysin regulates receptor tyrosine kinase signaling to Akt.

AKT1 MME

4.33e-05573220957047
Pubmed

Integrated Screens Identify CDK1 as a Therapeutic Target in Advanced Gastrointestinal Stromal Tumors.

AKT1 HNRNPUL1

4.33e-05573233727226
Pubmed

IkappaB kinase epsilon and TANK-binding kinase 1 activate AKT by direct phosphorylation.

AKT1 RICTOR

4.33e-05573221464307
Pubmed

Physical and functional characterization of the genetic locus of IBtk, an inhibitor of Bruton's tyrosine kinase: evidence for three protein isoforms of IBtk.

IBTK AKT1

4.33e-05573218596081
Pubmed

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.

WASHC5 SQLE

4.33e-05573224931836
Pubmed

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.

AKT1 RICTOR

4.33e-05573222521878
Pubmed

Neuronal AKAP150 coordinates PKA and Epac-mediated PKB/Akt phosphorylation.

RAPGEF4 AKT1

4.33e-05573218565730
Pubmed

Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis.

AKT1 RICTOR

4.33e-05573221339740
Pubmed

CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo.

AKT1 RICTOR

4.33e-05573219018001
Pubmed

CNS germinomas are characterized by global demethylation, chromosomal instability and mutational activation of the Kit-, Ras/Raf/Erk- and Akt-pathways.

AKT1 KIT

4.33e-05573227391150
Pubmed

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.

AKT1 RICTOR

4.33e-05573218566586
Pubmed

T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b.

AKT1 PRKCQ

4.33e-05573218227156
Pubmed

FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor.

AKT1 RICTOR

4.33e-05573220412774
Pubmed

Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer.

AKT1 KIT

4.33e-05573212140361
Pubmed

ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor.

AKT1 RICTOR

4.33e-05573221343617
Pubmed

Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival.

AKT1 RICTOR

4.33e-05573218776922
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

STRN PXDN WIZ GALNT3 NSD1 ANKRD17 MACF1 RICTOR CMSS1 ZNF593 CDC42BPB ZNF768

6.24e-051497731231527615
Pubmed

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

AKT1 RICTOR

6.48e-05673231996678
Pubmed

A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2.

AKT1 RICTOR

6.48e-05673221177249
Pubmed

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.

AKT1 RICTOR

6.48e-05673216962653
Pubmed

Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.

AKT1 RICTOR

6.48e-05673219299511
Pubmed

Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein.

AKT1 RICTOR

6.48e-05673222084251
Pubmed

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

AKT1 RICTOR

6.48e-05673218339839
Pubmed

mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.

AKT1 RICTOR

6.48e-05673229059166
Pubmed

Functional Analysis of KIT Gene Structural Mutations Causing the Porcine Dominant White Phenotype Using Genome Edited Mouse Models.

AKT1 KIT

6.48e-05673232194624
Pubmed

Cryo-EM structure of human mTOR complex 2.

AKT1 RICTOR

6.48e-05673229567957
Pubmed

Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling.

AKT1 RICTOR

6.48e-05673222307628
Pubmed

IKK interacts with rictor and regulates mTORC2.

AKT1 RICTOR

6.48e-05673223872070
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

PXDN TIAM1 ANKRD17 RICTOR CDC42BPB

6.86e-0520273533005030
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PCYT1A WIZ TIAM1 MYO1E ZBTB43 RAPGEF4 ZNF521 MACF1 HNRNPUL1 CTSL CDC42BPB

7.31e-051285731135914814
Pubmed

Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.

AKT1 RICTOR

9.06e-05773231442424
Pubmed

Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1.

AKT1 SEMA3E

9.06e-05773217318185
Pubmed

P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.

AKT1 RICTOR

9.06e-05773217565979
Pubmed

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.

AKT1 RICTOR

9.06e-05773217141160
Pubmed

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

AKT1 RICTOR

9.06e-05773215718470
Pubmed

Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.

AKT1 RICTOR

9.06e-05773222337773
Pubmed

Hematologic characterization and chromosomal localization of the novel dominantly inherited mouse hemolytic anemia, neonatal anemia (Nan).

KIT ZNF791

9.06e-05773219409822
Pubmed

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR).

AKT1 RICTOR

9.06e-05773219402821
Pubmed

Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.

AKT1 RICTOR

9.06e-05773226453307
Pubmed

PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development.

AKT1 RICTOR

9.06e-05773226453378
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

STRN WIZ WASHC5 ANKRD17 RICTOR

9.20e-0521573535973513
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF469 SKIDA1 ZNF833P

9.60e-054273334673265
Pubmed

Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.

AKT1 RICTOR

1.21e-04873217043309
Pubmed

Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.

AKT1 RICTOR

1.21e-04873225001283
Pubmed

KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development.

AKT1 KIT

1.21e-04873219914172
Pubmed

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling.

AKT1 RICTOR

1.21e-04873218566587
Pubmed

Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt.

AKT1 RICTOR

1.21e-04873225273559
Pubmed

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.

AKT1 RICTOR

1.21e-04873217386266
Pubmed

Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide.

AKT1 RICTOR

1.21e-04873224740015
Pubmed

Kit ligand has a critical role in mouse yolk sac and aorta-gonad-mesonephros hematopoiesis.

AKT1 KIT

1.55e-04973230166337
Pubmed

Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.

AKT1 RICTOR

1.55e-04973216962829
Pubmed

Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit.

AKT1 KIT

1.55e-04973218697750
Pubmed

Autoantibody of NRIP, a novel AChR-interacting protein, plays a detrimental role in myasthenia gravis.

RAPSN MACF1

1.93e-041073233773096
Pubmed

External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane.

TIAM1 AKT1

1.93e-041073222750946
Pubmed

Hsp70 associates with Rictor and is required for mTORC2 formation and activity.

AKT1 RICTOR

1.93e-041073218505677
Pubmed

PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12.

AKT1 RICTOR

1.93e-041073222609986
Pubmed

mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.

AKT1 RICTOR

2.36e-041173233052068
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

NUDT19 ARFGEF3 IBTK STRN TBRG4 WIZ MIGA2 COQ8B PRKCQ HNRNPUL1 YARS2

2.75e-041496731132877691
Pubmed

Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.

AKT1 RICTOR

2.83e-041273218851840
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

PXDN WIZ ASTE1 TOMM34 MACF1

3.19e-0428173524163370
Pubmed

mTOR controls embryonic and adult myogenesis via mTORC1.

AKT1 RICTOR

3.34e-041373230872276
Pubmed

HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.

STRN ZRANB1

3.34e-041373223277359
Pubmed

ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.

AKT1 RICTOR

3.34e-041373221795849
GeneFamilyBasic leucine zipper proteins|BTB domain containing

IBTK KLHL10 ZBTB43 ZBTB1 KLHL26

3.71e-05134515861
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

STRN PPP2R5A

8.00e-0415512696
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF469 WIZ ZBTB43 ZNF521 ZBTB1 ZNF791 ZNF768

3.83e-0371851728
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ARHGEF19 ZNF469 ADAMTS4 FRMD7 TOMM34 MME

6.55e-08127736c4809d8502f460370f824719d69b13b400a2b202
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRN PAFAH2 SOSTDC1 PRKCQ GFRA2 SEMA3E

5.85e-07184736e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRN SH2D4A SOSTDC1 PRKCQ GFRA2

1.17e-05180735da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRN SH2D4A SOSTDC1 PRKCQ GFRA2

1.17e-051807355b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRN SH2D4A SOSTDC1 PRKCQ GFRA2

1.17e-0518073550758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 MACF1 PRKCQ LY75 KIT

1.23e-05182735e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 MACF1 PRKCQ LY75 KIT

1.23e-051827351710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH2D4A SOSTDC1 PRKCQ GFRA2 SEMA3E

1.27e-05183735876b4f128c2168fdae7488201ff44f19c06c8415
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH2D4A SOSTDC1 PRKCQ GFRA2 SEMA3E

1.27e-05183735b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CTPS2 SKIDA1 COQ8B TOMM34 KIT

1.30e-05184735b8ecf58b3bdb25bcba5efc2d764930bb84ab95c8
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CTPS2 SKIDA1 COQ8B TOMM34 KIT

1.30e-05184735b232a9cc1d14e1a134b037016d437b93921a4a0f
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

TIAM1 SOSTDC1 MACF1 HPSE2 GFRA2

1.52e-0519073562a3ec1ae0829602b0569cc051210551644f1d46
ToppCellSecretory|World / shred by cell class for bronchial biopsy

ARFGEF3 IBTK FCGBP GALNT3 SQLE

1.72e-0519573552f8281fe0df67cec3faa780a23ed6343ed5a6ba
ToppCellnormal_Lung-Endothelial_cells-Tip-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

PXDN RAPGEF4 SOSTDC1 CCRL2 KIT

1.89e-0519973572c96a5954dfcfbfee8f095984ce1f5249d9a679
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 FCGBP GALNT3 SOSTDC1 PNPLA7

1.89e-05199735eb2d1b7e875c5bf833e7a80b43282e12893c34e9
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 STRN GALNT3 PNPLA7 SEMA3E

1.94e-05200735c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF469 PNLIP GALNT3 PRKCQ

6.78e-0513373463d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GALNT3 PAFAH2 PNPLA7 KIT

9.23e-05144734013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)|Striatum / BrainAtlas - Mouse McCarroll V32

ODF4 HPSE2 PRSS46P

1.25e-0459733a72de8cda377c87fa9a6fbda72735d850650f9f4
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Fos_(iSPN,_IEG+)-|Striatum / BrainAtlas - Mouse McCarroll V32

ODF4 HPSE2 PRSS46P

1.25e-04597333ab024fa7a927177da0dc764cee46dabdd008040
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-Langerhans_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCGBP TIAM1 SQLE TOMM34

1.29e-0415773410341ed8cbee0f636770a82cf580f6453bee8596
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTPS2 TIAM1 SOSTDC1 KIT

1.39e-04160734fe9970c160159b35f6599ed13c89cfb49264d554
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

ADHFE1 MACF1 MME GFRA2

1.52e-04164734519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

1.56e-04165734b1bbf5acdfc52bd8c7c7eb356d73b812eb6b908c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

1.56e-0416573428f8297ec7b781149cc7ac2f5e441771083b8ee3
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 SH2D4A SKIDA1 SEMA3E

1.60e-0416673411b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 KCNH7 RAPGEF4 CFAP61

1.60e-04166734f0912ce0df5ede3bc5e7c99ccfe4decc16c6064e
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 SH2D4A SKIDA1 SEMA3E

1.60e-04166734fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH2D4A RAPGEF4 CCRL2 HNRNPUL1

1.71e-041697345f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 ZNF593 KIT CTSL

1.83e-04172734a03f30a996a9474ad4cccd209476423a042df002
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 ZNF593 KIT CTSL

1.83e-04172734f92a53ad2e464cd68ba1714bcc1d5911479cdf1c
ToppCell3'_v3-blood-Mast|blood / Manually curated celltypes from each tissue

ZNF521 CCRL2 MME KIT

1.83e-04172734e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PXDN WIZ ASTE1 KLHL26

1.87e-04173734176d7dc103b8161c4e2d7dc74f2dc77ea1f2d2ed
ToppCell367C-Lymphocytic-ILC-ILC-2|367C / Donor, Lineage, Cell class and subclass (all cells)

ARHGEF19 ADAMTS4 WASHC5 LY75

1.87e-041737340451450605521fecb27a958628870d268adfb023
ToppCellSubstantia_nigra-Macroglia|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ARHGEF19 ADHFE1 ADAMTS4 PRKCQ

1.91e-041747347e7f7ca9a413ec255e54621800a279c771b9e6b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R5A SH2D4A FRMD7 KIT

1.95e-0417573498947a226b5a2ac7091ff9d34243ea7736add973
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARFGEF3 ADHFE1 FCGBP MIGA2

1.95e-04175734dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R5A SH2D4A FRMD7 KIT

2.00e-0417673425ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IBTK NSD1 MACF1 HNRNPUL1

2.00e-04176734749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell3'_v3-blood-Mast-Mast_cell_granulo-myelo|blood / Manually curated celltypes from each tissue

ZNF521 CCRL2 MME KIT

2.00e-04176734d421b6b8e13894dbcf29548c0a6516c3dee8f9b1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R5A SH2D4A TIAM1 FRMD7

2.00e-041767346c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FCGBP RAPSN CCRL2 CTSL

2.04e-04177734382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP PNLIP GALNT3

2.07e-0470733986c7a1002a4ffd3a246495bedde2997ffdc2c9d
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP PNLIP GALNT3

2.07e-0470733c0330216305491d7d57cdbea0ae3cb8e9092c8e3
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP PNLIP GALNT3

2.07e-047073386dde790fcdaec2095e2256463953077811145d2
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FCGBP PNLIP GALNT3

2.07e-0470733e604660b2efbc03e21806dcaecf7a72321673ae2
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN PAFAH2 COQ8B PRKCQ

2.08e-0417873441745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN PAFAH2 COQ8B PRKCQ

2.08e-04178734eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF19 SOSTDC1 GFRA2 SEMA3E

2.08e-041787343e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WASHC5 CCRL2 CMSS1 CTSL

2.13e-041797346624a2e731ab2d6c2eec19445e3dc509f581a8a9
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

KCNH7 FCGBP SH2D4A RAPGEF4

2.17e-04180734289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCellNS-critical-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 CPTP SH2D4A SOSTDC1

2.22e-04181734cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WASHC5 PAFAH2 ZBTB1 CDC42BPB

2.22e-041817343fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL10 SH2D4A PAFAH2 CDC42BPB

2.27e-0418273439f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAFAH2 SOSTDC1 GFRA2 SEMA3E

2.27e-041827346fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP SH2D4A PNLIP SOSTDC1

2.27e-04182734b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP SH2D4A PNLIP SOSTDC1

2.27e-04182734cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.32e-04183734262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.32e-04183734c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZNF469 PNLIP GALNT3

2.35e-0473733562f2264476e5402eda1cf0c8b28c3d325cbc6f1
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZNF469 PNLIP GALNT3

2.35e-04737336b1971d4a50a1f644f70b3e08b9a825434cc6f0c
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 FCGBP SOSTDC1 ACOT4

2.36e-041847347cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 FCGBP SOSTDC1 ACOT4

2.36e-0418473453b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS4 RAPGEF4 KIT CDC42BPB

2.41e-04185734673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS4 RAPGEF4 KIT GFRA2

2.46e-04186734e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PPP1R21 PXDN RAPGEF4 SOSTDC1

2.57e-04188734fe7143c36e4a883745862d3c3147cf751b440e46
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

PPP1R21 PXDN RAPGEF4 SOSTDC1

2.57e-04188734cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP SH2D4A GALNT3 KIT

2.67e-041907340bad41d19dc515e6bc61e699f4d56664cf2e72fd
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PXDN RICTOR MME PNPLA7

2.72e-0419173440813c397f533c2f4a6359a77757f736b6d9e07d
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP TIAM1 SOSTDC1 SEMA3E

2.72e-04191734ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNH7 MYO1E RAPGEF4 ZNF521

2.72e-04191734a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.78e-041927348ad6678df89175c5a4a835c8566f1552df3c996e
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.78e-0419273404f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1E ADAMTS4 RAPGEF4 ZNF521

2.78e-04192734c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.78e-04192734c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.78e-041927342f5378ea0b2fb2f672a36585d375f675983363a1
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.83e-04193734e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACF1 HPSE2 MME SEMA3E

2.83e-041937349f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.83e-0419373402f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 FCGBP GALNT3 KIT

2.83e-041937346a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.83e-041937346e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.83e-04193734f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.83e-04193734af5108260783e69a7d67896c5bf64f862525926d
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.83e-04193734e1d546165dcc2392f540162206852c4717d7306f
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPP2R5A RAPGEF4 ZNF521 KIT

2.83e-041937345122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.83e-041937344ccf984baebbb13ae916727137ce593fda7514a2
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP SH2D4A GALNT3 KIT

2.89e-04194734550e61a40be2baa59520aaf5912bb99ad094ba15
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACF1 HPSE2 MME SEMA3E

2.89e-0419473471d3c7448b1734de54187f902f65649f9283bd4c
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 ZNF521 MACF1 KIT

2.89e-041947340b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1E RAPGEF4 ZNF521 KIT

2.89e-0419473458f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1E RAPGEF4 ZNF521 KIT

2.89e-04194734bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellMonocytes-Phagocytic_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

MYO1E CCRL2 CTSL GFRA2

2.89e-0419473440dbfdf1d7e6b73d120d8f802f08e573fe9a739e
ToppCellIPF-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

PXDN ADAMTS4 RAPGEF4 ZNF521

2.95e-04195734120296531bbc8080dcabacbd64733cc1dc34603a
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTS4 RAPGEF4 ZNF521 MACF1

2.95e-04195734a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 MME CTSL GFRA2

2.95e-041957346bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.95e-0419573419347b7e8d3ea67e0fddd948078abcab9d364a2d
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCRL2 PRKCQ MME KIT

2.95e-04195734c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCellIPF-Endothelial-VE_Peribronchial|IPF / Disease state, Lineage and Cell class

PXDN ADAMTS4 RAPGEF4 ZNF521

2.95e-041957342c3ad3cb79f11119ac69c413a938d21199145040
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOSTDC1 PRKCQ KIT CTSL

2.95e-0419573455b4030f078173b0136990fae87b6eaf44c58f33
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 MME CTSL GFRA2

2.95e-04195734a3b468125e48f072255cede7645f6692298ecf54
DiseaseAdenocarcinoma of large intestine

AKT1 PRKCQ KIT CDC42BPB

8.65e-0596714C1319315
Diseaselevel of Sphingomyelin (d36:2) in blood serum

RAPSN ANKRD17

1.19e-047712OBA_2045177
DiseaseClear Cell Meningioma

AKT1 CTSL

3.71e-0412712C0431121
DiseaseIntraventricular Meningioma

AKT1 CTSL

3.71e-0412712C1334271
DiseaseBenign Meningioma

AKT1 CTSL

3.71e-0412712C0281784
DiseaseIntraorbital Meningioma

AKT1 CTSL

3.71e-0412712C1334261
DiseaseOlfactory Groove Meningioma

AKT1 CTSL

3.71e-0412712C1335107
DiseaseAngioblastic Meningioma

AKT1 CTSL

3.71e-0412712C1527197
DiseaseMeningiomas, Multiple

AKT1 CTSL

3.71e-0412712C0205834
DiseaseXanthomatous Meningioma

AKT1 CTSL

3.71e-0412712C0457190
DiseaseAngiomatous Meningioma

AKT1 CTSL

3.71e-0412712C0334608
DiseasePsammomatous Meningioma

AKT1 CTSL

3.71e-0412712C0334607
DiseaseFibrous Meningioma

AKT1 CTSL

3.71e-0412712C0334606
DiseaseMeningothelial meningioma

AKT1 CTSL

3.71e-0412712C0334605
DiseaseHemangioblastic Meningioma

AKT1 CTSL

3.71e-0412712C0334609
DiseaseTransitional Meningioma

AKT1 CTSL

3.71e-0412712C0334611
DiseaseHemangiopericytic Meningioma

AKT1 CTSL

3.71e-0412712C0334610
DiseaseSpinal Meningioma

AKT1 CTSL

3.71e-0412712C0347515
DiseaseIntracranial Meningioma

AKT1 CTSL

3.71e-0412712C0349604
DiseasePapillary Meningioma

AKT1 CTSL

3.71e-0412712C3163622
DiseaseMalignant Meningioma

AKT1 CTSL

3.71e-0412712C0259785
DiseaseSphenoid Wing Meningioma

AKT1 CTSL

3.71e-0412712C1565951
DiseasePosterior Fossa Meningioma

AKT1 CTSL

3.71e-0412712C1565950
DiseaseParasagittal Meningioma

AKT1 CTSL

3.71e-0412712C0751304
DiseaseCerebral Convexity Meningioma

AKT1 CTSL

3.71e-0412712C0751303
DiseaseMicrocystic meningioma

AKT1 CTSL

3.71e-0412712C1384408
DiseaseSecretory meningioma

AKT1 CTSL

3.71e-0412712C1384406
Diseaselevel of Sphingomyelin (d34:2) in blood serum

RAPSN ANKRD17

4.38e-0413712OBA_2045174
Diseasecancer (implicated_via_orthology)

PPP2R5A SQLE MACF1 AKT1 KIT

4.75e-04268715DOID:162 (implicated_via_orthology)
Diseaselevel of Phosphatidylethanolamine (18:1_18:1) in blood serum

RAPSN MYO1E

5.10e-0414712OBA_2045142
Diseasevitamin C measurement

RAPSN AKT1

6.70e-0416712EFO_0600003
Diseasetemporal horn of lateral ventricle volume measurement

RAPGEF4 SOSTDC1 SEMA3E

7.07e-0472713EFO_0010333
Diseasecystathionine measurement

SH2D4A GFRA2

9.51e-0419712EFO_0010474
Diseaselevel of Phosphatidylethanolamine (18:0_20:4) in blood serum

RAPSN MYO1E

9.51e-0419712OBA_2045140
Diseaselevel of Sphingomyelin (d38:2) in blood serum

RAPSN ANKRD17

9.51e-0419712OBA_2045179
DiseaseMeningioma

AKT1 CTSL

9.51e-0419712C0025286
Disease5alpha-androstan-3beta,17beta-diol disulfate measurement

PCYT1A PRKCQ

1.28e-0322712EFO_0021115
Diseaselevel of Sphingomyelin (d40:2) in blood serum

RAPSN ANKRD17

1.40e-0323712OBA_2045181
DiseaseNeoplasm of the genitourinary tract

AKT1 KIT

1.52e-0324712cv:C0042065
Diseaselevel of Phosphatidylethanolamine (16:0_18:2) in blood serum

RAPSN MYO1E

1.52e-0324712OBA_2045136
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

RAPSN ANKRD17

1.79e-0326712OBA_2045194
Diseaselevel of Phosphatidylethanolamine (18:0_18:2) in blood serum

RAPSN MYO1E

2.07e-0328712OBA_2045139
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

MYO1E COQ8B

2.38e-0330712C1868672

Protein segments in the cluster

PeptideGeneStartEntry
TALKYSFQTHDRLCF

AKT1

211

P31749
FLASDHCFNDKDYAL

CFAP61

716

Q8NHU2
HFSLSDCKSSYNLDK

CCRL2

266

O00421
TFSKYLCRCFHLRSN

CCRL2

306

O00421
CFLKANDLTHSLSSY

CMSS1

121

Q9BQ75
AHCTAAALAALSLYN

BTBD11

176

A6QL63
HSNEFKESALTLACY

ANKRD17

396

O75179
DGYALFHRLCFSSNL

ASTE1

31

Q2TB18
VAYHANDFCLAAGSK

NSD1

1666

Q96L73
YLNLARSNEKLCEFH

RAPSN

86

Q13702
LHFYKSRSCSDLENG

ODF4

136

Q2M2E3
SSKAVYLHLFNDCLL

ARHGEF19

616

Q8IW93
QSCHKFDLSRATFYA

PRKCQ

471

Q04759
AFLASKNCIHRDLAA

KIT

781

P10721
RLANFASLSDLHKFC

NUDT19

266

A8MXV4
GTRDFAACNHLRSYK

PNLIP

271

P16233
FLSSHCYNAATIKDV

IBTK

36

Q9P2D0
SNADVRALTYCDLHK

KCNH7

821

Q9NS40
SCSHLNLAEKEYFGL

FRMD7

31

Q6ZUT3
CSPANLSRHKAAAYD

PCYT1A

346

P49585
SAEFSEAFHCRKNSY

MME

726

P08473
CYKSDQALHSFSEAK

LY75

1546

O60449
LGCYSDQDFLAKLHC

MIGA2

341

Q7L4E1
CSHSALRRDKYVAEF

CDC42BPB

41

Q9Y5S2
DSKSVHFYAECRALS

PPP1R21

686

Q6ZMI0
SLDKLYNFADCSGLH

HPSE2

206

Q8WWQ2
LTAATDACRLYATKH

RICTOR

721

Q6R327
NRDCSFLSISKAHFY

PNPLA7

546

Q6ZV29
LNALNKAYHDLCDGS

MACF1

1511

Q9UPN3
QCAAYNHRTDLFKSF

ADAMTS4

586

O75173
SAHKNILCSCSSYFR

KLHL10

51

Q6JEL2
AHKVVLAACSDYFRA

KLHL26

76

Q53HC5
SRLADFHANCRASYQ

GFRA2

266

O00451
DKAFLCRSLAAYTAA

FCGBP

5086

Q9Y6R7
AKHCFNAFASDRISL

GALNT3

146

Q14435
ADSLYTAAHCALLLN

ARFGEF3

731

Q5TH69
ALCADSYNASLAAYH

CPTP

136

Q5TA50
DDSLHQLRKACFLYF

SQLE

481

Q14534
YALHRKLAGAFLACA

COQ8B

486

Q96D53
YSLCGAAHLLAAADK

LBX1

51

P52954
AAHCLQRFKDLSLYS

PRSS46P

81

E5RG02
YKHLAFLAESCATLS

TBRG4

181

Q969Z0
HRDRSAATTYFCKQA

PAFAH2

136

Q99487
KSNSLDHFYCDRGQL

OR9A2

166

Q8NGT5
YNCDLHFKVARDRSS

HNRNPUL1

216

Q9BUJ2
CKAANLYASSPHSDF

ADHFE1

146

Q8IWW8
AAHCKEYKNLNSFFA

RAPGEF4

851

Q8WZA2
AYSAAHQRLLSCSAD

STRN

576

O43815
AKRCTQALYHSSIDA

YARS2

366

Q9Y2Z4
ANFLYHLASAAAATK

SKIDA1

481

Q1XH10
LCGLYFENRKALASH

WIZ

1401

O95785
TAKGLALFHAQLAYC

PPP2R5A

281

Q15172
EKGALFRAHARYCAD

ACOT4

41

Q8N9L9
KDRRNHCGIASAASY

CTSL

316

P07711
AHKAVLAASSPYFCD

ZBTB43

46

O43298
CGKAFRYSSSIRNHE

ZNF833P

71

Q6ZTB9
SVLYSNRAACHLKDG

TOMM34

51

Q15785
RDCYASVFKALEHSA

CTPS2

311

Q9NRF8
ECEKAFSYLKSFQRH

ZNF791

136

Q3KP31
NYSCRFDSKHLAAAL

WASHC5

966

Q12768
ADRFKLYSAFCASHT

TIAM1

1136

Q13009
QFCDKSFSRLSYLKH

ZNF521

121

Q96K83
ALATLALNYSVCFHK

PLAA

701

Q9Y263
YCNLSAAHTFEDLKN

PXDN

1176

Q92626
RCGKAFADSSYLLRH

ZNF768

321

Q9H5H4
CKHFLIDASADAYSF

SH2D4A

391

Q9H788
CLAFKNDATEILYSH

SOSTDC1

21

Q6X4U4
CDRNYSSLAAFLAHR

ZNF469

736

Q96JG9
QAHKAVLAACSSYFR

ZBTB1

36

Q9Y2K1
CARYFIDSTNLKTHF

ZNF593

66

O00488
RDHSNCSLSFYALSN

ZACN

166

Q401N2
FLRLHKSDAGTYFCQ

SEMA3E

641

O15041
LKCAHYFILAASRGD

LCMT2

301

O60294
ASLHQRKGDFACYFL

ZRANB1

361

Q9UGI0
EQACYTRDALAKALH

MYO1E

346

Q12965