Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	WD40	FZR1 WDR75 MED16 NSMAF	3.63e-04	259	25	4	PF00400
Domain	WD40	FZR1 WDR75 MED16 NSMAF	4.14e-04	268	25	4	SM00320
Domain	WD40_repeat	FZR1 WDR75 MED16 NSMAF	4.37e-04	272	25	4	IPR001680
Domain	WD_REPEATS_1	FZR1 WDR75 MED16 NSMAF	4.75e-04	278	25	4	PS00678
Domain	WD_REPEATS_2	FZR1 WDR75 MED16 NSMAF	4.81e-04	279	25	4	PS50082
Domain	WD_REPEATS_REGION	FZR1 WDR75 MED16 NSMAF	4.81e-04	279	25	4	PS50294
Domain	WD40_repeat_dom	FZR1 WDR75 MED16 NSMAF	6.09e-04	297	25	4	IPR017986
Domain	-	FZR1 WDR75 MED16 NSMAF	9.34e-04	333	25	4	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	FZR1 WDR75 MED16 NSMAF	9.55e-04	335	25	4	IPR015943
Domain	Ank	TNKS CAMTA2 TRPC5	3.39e-03	228	25	3	PF00023
Domain	-	TNKS CAMTA2 TRPC5	4.29e-03	248	25	3	1.25.40.20
Domain	ANK_REPEAT	TNKS CAMTA2 TRPC5	4.53e-03	253	25	3	PS50088
Domain	Ankyrin_rpt-contain_dom	TNKS CAMTA2 TRPC5	4.58e-03	254	25	3	IPR020683
Domain	ANK_REP_REGION	TNKS CAMTA2 TRPC5	4.58e-03	254	25	3	PS50297
Domain	Ankyrin_rpt	TNKS CAMTA2 TRPC5	5.00e-03	262	25	3	IPR002110
Domain	Ion_trans_dom	TRPM3 TRPC5	1.01e-02	114	25	2	IPR005821
Domain	Ion_trans	TRPM3 TRPC5	1.01e-02	114	25	2	PF00520
Pathway	REACTOME_TRP_CHANNELS	TRPM3 TRPC5	3.93e-04	28	15	2	M27241
Pathway	REACTOME_TRP_CHANNELS	TRPM3 TRPC5	3.93e-04	28	15	2	MM14943
Pubmed	Inhibition of endothelial cell Ca²⁺ entry and transient receptor potential channels by Sigma-1 receptor ligands.	TRPM3 TRPC5	1.74e-06	3	27	2	23121507
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	1.74e-06	3	27	2	26542179
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SPTBN4 RESF1 AARS2 SSPOP	3.06e-06	130	27	4	12421765
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SPTBN4 RESF1 TRPM3	6.61e-05	101	27	3	10997877
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	OGDHL FZR1 AARS2	7.01e-05	103	27	3	10574462
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPM3 TRPC5	1.59e-04	24	27	2	33884443
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPM3 TRPC5	1.72e-04	25	27	2	16382100
Pubmed	An introduction to TRP channels.	TRPM3 TRPC5	2.01e-04	27	27	2	16460286
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	IPO5 TNKS RESF1	2.17e-04	151	27	3	17043677
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPM3 TRPC5	3.02e-04	33	27	2	19834762
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	TRPM3 TRPC5	5.38e-04	44	27	2	19322198
Pubmed	Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin.	IPO5 MED16	6.40e-04	48	27	2	27703004
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	RESF1 TTC7B AARS2	7.71e-04	233	27	3	37704626
Interaction	TCAIM interactions	OGDHL AARS2	1.47e-05	5	25	2	int:TCAIM
Cytoband	10q22.3	NUTM2E NUTM2B	2.96e-04	43	27	2	10q22.3
Cytoband	Ensembl 112 genes in cytogenetic band chr10q22	NUTM2E NUTM2B	6.66e-03	208	27	2	chr10q22
Cytoband	19p13.3	FZR1 MED16	8.56e-03	237	27	2	19p13.3
GeneFamily	WD repeat domain containing	FZR1 WDR75 MED16 NSMAF	1.12e-04	262	18	4	362
GeneFamily	Transient receptor potential cation channels	TRPM3 TRPC5	3.48e-04	28	18	2	249
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	1.03e-05	6	25	2	C0334488
Disease	lysophosphatidylethanolamine 20:4 measurement	TNKS DOK7	2.76e-04	29	25	2	EFO_0010370
Disease	lysophosphatidylcholine 20:4 measurement	TNKS DOK7	3.37e-04	32	25	2	EFO_0010363
Disease	diglyceride measurement	IFT22 DOK7	8.57e-04	51	25	2	EFO_0010223
Disease	susceptibility to rubella infection measurement	TTC7B TRPM3	8.90e-04	52	25	2	EFO_0008418
Disease	polyp of colon	FZR1 DOK7	1.03e-03	56	25	2	MONDO_0021400
Disease	diastolic blood pressure, systolic blood pressure	MTNR1B TRPM3 DOK7 NSMAF	2.28e-03	670	25	4	EFO_0006335, EFO_0006336

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLHMDFWCARLATKG	ACRBP	436	Q8NEB7
MWACALGHLEAAVLL	CAMTA2	761	O94983
VRKHASWAVMVCAGD	ARMC3	496	Q5W041
SGHDLSEWLKGCDMH	SPACA5	136	Q96QH8
WALGEEHCKASAFVM	MTNR1B	106	P49286
GAELAWCQEEHKNMG	OGDHL	936	Q9ULD0
ALCWHLQMLAKVADG	AP5B1	536	Q2VPB7
WHFMCDALIKAIGTE	IPO5	746	O00410
ADGQIKCWSMADHLA	MED16	101	Q9Y2X0
WDAAAGKKLSMLEGH	FZR1	256	Q9UM11
ESCWPALMKDAHGVV	IFT22	71	Q9H7X7
MGHDDAVSKICWHDN	NSMAF	711	Q92636
AIMLGFDSHEAMCAW	DOK7	86	Q18PE1
WKGNSGSCLMAEALH	NUTM2B	36	A6NNL0
WKGNSGSCLMAEALH	NUTM2E	36	B1AL46
ALAKASPEGHCFAMW	SSPOP	106	A2VEC9
EKDDIHCCALGWLSM	RESF1	1166	Q9HCM1
DEAWRLGCMAKHTAT	AARS2	621	Q5JTZ9
MKACDLGHIWACANA	COA7	176	Q96BR5
DCIASGHMDGKIRLW	WDR75	216	Q8IWA0
WQHGEEAMAKALVAC	TRPM3	681	Q9HCF6
LLKHGACVNAMDLWQ	TNKS	421	O95271
WSEAMAHGCFLNAKR	PRAMEF5	116	Q5TYX0
ECGHTAAATMAEWKD	SPTBN4	1796	Q9H254
HMAEKLCEAWAFGQS	TMEM201	281	Q5SNT2
LAAKLCMGSLHWLEE	TTC7B	436	Q86TV6
CMGSLHWLEEAEKFA	TTC7B	441	Q86TV6
AIWAGLMAACHADDK	TTC37	1271	Q6PGP7
VFETWGEACDLLMHK	TRPC5	946	Q9UL62
GEACDLLMHKWGDGQ	TRPC5	951	Q9UL62