Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	postsynaptic density assembly	RELN PTPRD SIPA1L1 LRRTM2	8.47e-06	34	79	4	GO:0097107
GeneOntologyBiologicalProcess	postsynaptic specialization assembly	RELN PTPRD SIPA1L1 LRRTM2	2.41e-05	44	79	4	GO:0098698
GeneOntologyBiologicalProcess	excitatory synapse assembly	RELN PTPRD SIPA1L1 LRRTM2	2.88e-05	46	79	4	GO:1904861
GeneOntologyBiologicalProcess	postsynapse assembly	RELN PTPRD SIPA1L1 LRRTM2 NECTIN3	2.90e-05	93	79	5	GO:0099068
GeneOntologyBiologicalProcess	regulation of postsynaptic density assembly	PTPRD SIPA1L1 LRRTM2	6.84e-05	21	79	3	GO:0099151
GeneOntologyBiologicalProcess	postsynaptic density organization	RELN PTPRD SIPA1L1 LRRTM2	7.23e-05	58	79	4	GO:0097106
GeneOntologyBiologicalProcess	regulation of postsynaptic specialization assembly	PTPRD SIPA1L1 LRRTM2	1.32e-04	26	79	3	GO:0099150
GeneOntologyBiologicalProcess	regulation of excitatory synapse assembly	PTPRD SIPA1L1 LRRTM2	1.32e-04	26	79	3	GO:1904889
GeneOntologyBiologicalProcess	regulation of postsynaptic density organization	PTPRD SIPA1L1 LRRTM2	1.48e-04	27	79	3	GO:1905874
GeneOntologyBiologicalProcess	postsynaptic specialization organization	RELN PTPRD SIPA1L1 LRRTM2	1.59e-04	71	79	4	GO:0099084
GeneOntologyBiologicalProcess	smooth muscle tissue development	COL3A1 FOXP2 PDGFRB	1.84e-04	29	79	3	GO:0048745
Domain	Transket_pyr	TKTL1 DHTKD1	4.87e-04	8	79	2	SM00861
Domain	Transket_pyr	TKTL1 DHTKD1	4.87e-04	8	79	2	PF02779
Domain	Transketolase-like_Pyr-bd	TKTL1 DHTKD1	4.87e-04	8	79	2	IPR005475
Domain	C2-set_2	MAG NECTIN3 CD200R1	6.92e-04	41	79	3	PF08205
Domain	CD80_C2-set	MAG NECTIN3 CD200R1	6.92e-04	41	79	3	IPR013162
Domain	Fib_collagen_C	COL3A1 COL11A1	9.48e-04	11	79	2	IPR000885
Domain	COLFI	COL3A1 COL11A1	9.48e-04	11	79	2	PF01410
Domain	NC1_FIB	COL3A1 COL11A1	9.48e-04	11	79	2	PS51461
Domain	Fib_collagen_C	COL3A1 COL11A1	9.48e-04	11	79	2	PD002078
Domain	Tyr_kinase_rcpt_2_CS	DDR1 INSRR	9.48e-04	11	79	2	IPR002011
Domain	COLFI	COL3A1 COL11A1	9.48e-04	11	79	2	SM00038
Domain	RECEPTOR_TYR_KIN_II	DDR1 INSRR	1.13e-03	12	79	2	PS00239
Domain	THDP-binding	TKTL1 DHTKD1	1.34e-03	13	79	2	IPR029061
Domain	-	TKTL1 DHTKD1	1.34e-03	13	79	2	3.40.50.970
Domain	Pkinase_Tyr	DDR1 RIPK1 PDGFRB INSRR	2.19e-03	129	79	4	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	DDR1 RIPK1 PDGFRB INSRR	2.79e-03	138	79	4	IPR001245
Domain	PAS_fold_3	AHR SIM2	4.22e-03	23	79	2	IPR013655
Domain	PAS_3	AHR SIM2	4.22e-03	23	79	2	PF08447
Domain	PAS-assoc_C	AHR SIM2	4.59e-03	24	79	2	IPR000700
Domain	PAS	AHR SIM2	4.98e-03	25	79	2	PF00989
Domain	PAS_fold	AHR SIM2	4.98e-03	25	79	2	IPR013767
Domain	PAC	AHR SIM2	5.38e-03	26	79	2	IPR001610
Domain	PAC	AHR SIM2	5.38e-03	26	79	2	SM00086
Domain	PAC	AHR SIM2	5.38e-03	26	79	2	PS50113
Domain	TyrKc	DDR1 PDGFRB INSRR	6.18e-03	88	79	3	SM00219
Domain	Tyr_kinase_cat_dom	DDR1 PDGFRB INSRR	6.18e-03	88	79	3	IPR020635
Domain	Alkaline_phosphatase_core	SGSH ENPP5	7.59e-03	31	79	2	IPR017850
Domain	Alkaline_Pase-like_a/b/a	SGSH ENPP5	7.59e-03	31	79	2	IPR017849
Domain	-	SGSH ENPP5	7.59e-03	31	79	2	3.40.720.10
Domain	PAS	AHR SIM2	8.07e-03	32	79	2	SM00091
Domain	PROTEIN_KINASE_TYR	DDR1 PDGFRB INSRR	8.08e-03	97	79	3	PS00109
Domain	Tyr_kinase_AS	DDR1 PDGFRB INSRR	8.08e-03	97	79	3	IPR008266
Pubmed	An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors.	COL3A1 DDR1 COL11A1	1.21e-07	5	81	3	9659900
Pubmed	The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1.	RIPK1 OTUD6B	5.36e-06	2	81	2	38880876
Pubmed	Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells.	PDGFRB LOX	5.36e-06	2	81	2	18586678
Pubmed	Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food.	TLR5 AHR	5.36e-06	2	81	2	37742185
Pubmed	The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.	MAG FOXP2 LRRTM3	8.08e-06	17	81	3	34184027
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RELN SORBS2 PTPRD BRD2 PDGFRB JADE2 SUPT5H SIPA1L1 ZNF189 ENPP5 SIM2 RSBN1L B4GALT3	8.18e-06	1285	81	13	35914814
Pubmed	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	COL11A1 FOXP2 BMP10 ZNF189 AHR SHMT1 NECTIN3	1.26e-05	331	81	7	20634891
Pubmed	Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling.	TXNRD1 PDGFRB	1.60e-05	3	81	2	23901112
Pubmed	Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain.	RELN FOXP2	1.60e-05	3	81	2	12687690
Pubmed	Reelin activates the small GTPase TC10 and VAMP7 to promote neurite outgrowth and regeneration of dorsal root ganglia (DRG) neurons.	RHOQ RELN	1.60e-05	3	81	2	32652719
Pubmed	Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1.	COL3A1 DDR1	1.60e-05	3	81	2	21044884
Pubmed	Expression profile of receptor-type protein tyrosine kinase genes in the human thyroid.	DDR1 PDGFRB	1.60e-05	3	81	2	9492013
Pubmed	Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis.	PTPRD PDGFRB	1.60e-05	3	81	2	35848503
Pubmed	SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation.	COL3A1 RIPK1 PDGFRB	2.08e-05	23	81	3	36414671
Pubmed	Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis.	LRRTM2 LRRTM3	3.20e-05	4	81	2	16860615
Pubmed	Single-cell transcriptomic analysis of mouse neocortical development.	COL3A1 RELN FOXP2 SLC6A20 NECTIN3	4.99e-05	170	81	5	30635555
Pubmed	Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein.	AHR SIM2	5.33e-05	5	81	2	9020169
Pubmed	Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development.	COL3A1 DDR1	5.33e-05	5	81	2	11283268
Pubmed	Methylation of SPT5 regulates its interaction with RNA polymerase II and transcriptional elongation properties.	SUPT5H PRMT1	5.33e-05	5	81	2	12718890
Pubmed	A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system.	LRRTM2 LRRTM3	5.33e-05	5	81	2	12676565
Pubmed	Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.	MAG RELN FOXP2 NECTIN3	5.49e-05	88	81	4	21491433
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	FARSA COL11A1 LOX UGGT1 AHR PRMT1 UNC45A RSRC2 RSBN1L ITPA NCBP3 RBM17	7.68e-05	1371	81	12	36244648
Pubmed	Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development.	AHR SIM2	7.99e-05	6	81	2	11025203
Pubmed	ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development.	COL3A1 COL11A1	7.99e-05	6	81	2	17029294
Pubmed	Characterization of G protein-coupled receptor 56 protein expression in the mouse developing neocortex.	COL3A1 RELN	7.99e-05	6	81	2	22351047
Pubmed	The discoidin domain receptor tyrosine kinases are activated by collagen.	COL3A1 DDR1	7.99e-05	6	81	2	9659899
Pubmed	Specificity and structure of a high affinity activin receptor-like kinase 1 (ALK1) signaling complex.	BMP10 ACVR2A	7.99e-05	6	81	2	22718755
Pubmed	The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells.	RELN FOXP2	7.99e-05	6	81	2	16680166
Pubmed	Gene expression analysis of the embryonic subplate.	RELN HEG1 FOXP2 LRRTM3 ZHX1	9.78e-05	196	81	5	21862448
Pubmed	Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.	TLR5 AHR	1.12e-04	7	81	2	22306017
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	DDR1 PDGFRB INSRR	1.13e-04	40	81	3	30898150
Pubmed	Extracellular-matrix gene expression during mouse submandibular gland development.	COL3A1 LOX	1.49e-04	8	81	2	9382709
Pubmed	Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis.	COL3A1 COL11A1	1.49e-04	8	81	2	9164858
Pubmed	Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance.	COL3A1 COL11A1	1.49e-04	8	81	2	18816857
Pubmed	Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors.	AHR SIM2	1.49e-04	8	81	2	11782478
Pubmed	Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues.	RELN NECTIN3	1.91e-04	9	81	2	23931996
Pubmed	Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock.	AHR SIM2	1.91e-04	9	81	2	9704006
Pubmed	Mesenchymal condensation-dependent accumulation of collagen VI stabilizes organ-specific cell fates during embryonic tooth formation.	COL3A1 LOX	1.91e-04	9	81	2	25715693
Pubmed	Cell cycle during neuronal migration and neocortical lamination.	RELN FOXP2	1.91e-04	9	81	2	33448039
Pubmed	Foxg1 suppresses early cortical cell fate.	RELN FOXP2	1.91e-04	9	81	2	14704420
Pubmed	Projections and interconnections of genetically defined serotonin neurons in mice.	COL3A1 RELN	1.91e-04	9	81	2	22151329
Pubmed	Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth.	RELN FOXP2	1.91e-04	9	81	2	16387638
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	DDR1 RIPK1 FOXP2 PDGFRB INSRR SIM2	2.38e-04	372	81	6	22939624
Pubmed	Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development.	RELN FOXP2	2.38e-04	10	81	2	29127326
Pubmed	Kif14 mutation causes severe brain malformation and hypomyelination.	MAG FOXP2	2.38e-04	10	81	2	23308235
Pubmed	Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.	RELN FOXP2	2.38e-04	10	81	2	22479190
Pubmed	Characterization of binding properties of the myelin-associated glycoprotein to extracellular matrix constituents.	COL3A1 MAG	2.38e-04	10	81	2	2446864
Pubmed	Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex.	RELN FOXP2	2.38e-04	10	81	2	17507397
Pubmed	Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo.	RELN FOXP2	2.38e-04	10	81	2	19389366
Pubmed	G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination.	COL3A1 RELN	2.38e-04	10	81	2	21768377
Pubmed	Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis.	SHMT1 ITPA	2.38e-04	10	81	2	19858780
Pubmed	Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity.	MAG LILRA1	2.91e-04	11	81	2	21364532
Pubmed	Active intermixing of indirect and direct neurons builds the striatal mosaic.	RELN FOXP2	2.91e-04	11	81	2	30413696
Pubmed	ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex.	RELN FOXP2	2.91e-04	11	81	2	27909010
Pubmed	Dual Role of Rbpj in the Maintenance of Neural Progenitor Cells and Neuronal Migration in Cortical Development.	RELN FOXP2	3.48e-04	12	81	2	32780108
Pubmed	A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors.	RELN FOXP2	3.48e-04	12	81	2	22246438
Pubmed	The Forkhead box F1 transcription factor inhibits collagen deposition and accumulation of myofibroblasts during liver fibrosis.	COL3A1 MMP16	3.48e-04	12	81	2	30670377
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	RIPK1 MGST3 UGGT1 SRM	3.57e-04	143	81	4	30397336
Pubmed	ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.	BRD2 SUPT5H SNAP29	3.60e-04	59	81	3	34108663
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	SORBS2 PTPRD FOXP2 PCDH15 MMP16	3.95e-04	265	81	5	19240061
Pubmed	Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System.	MAG PRMT1	4.11e-04	13	81	2	26637354
Pubmed	Novel markers reveal subpopulations of subplate neurons in the murine cerebral cortex.	RELN FOXP2	4.11e-04	13	81	2	19008461
Pubmed	Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.	DDR1 PDGFRB	4.11e-04	13	81	2	36198802
Pubmed	Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse.	RIPK1 WRNIP1	4.11e-04	13	81	2	11863365
Pubmed	Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain.	RELN FOXP2	4.79e-04	14	81	2	22821687
Pubmed	Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system.	RELN FOXP2	4.79e-04	14	81	2	15964824
Pubmed	Membrane-type MMPs are indispensable for placental labyrinth formation and development.	COL3A1 MMP16	4.79e-04	14	81	2	20858856
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	FARSA VPS13D LCTL ZC3H12B RSBN1L	4.83e-04	277	81	5	30745168
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	DDR1 SORBS2 BRD2 PDGFRB LOX PRMT1 SLC5A12 ZHX1 RSBN1L RBM17	5.17e-04	1215	81	10	15146197
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	TXNRD1 OSBP FARSA SUPT5H OTUD6B UGGT1 WRNIP1 SHMT1 PRMT1 UNC45A PAIP1	5.46e-04	1455	81	11	22863883
Pubmed	Collagen II is essential for the removal of the notochord and the formation of intervertebral discs.	COL3A1 COL11A1	5.52e-04	15	81	2	9832566
Pubmed	A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse.	FOXP2 NECTIN3	5.52e-04	15	81	2	23727838
Pubmed	Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells.	RELN NECTIN3	5.52e-04	15	81	2	24115331
Pubmed	Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2.	RELN FOXP2	5.52e-04	15	81	2	22573669
Pubmed	Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain.	RELN PDGFRB	5.52e-04	15	81	2	29901792
Pubmed	Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling.	RIPK1 WRNIP1	5.52e-04	15	81	2	24726327
Pubmed	The DNA sequence and analysis of human chromosome 6.	ILRUN DDR1 MLIP BRD2 GCM2 RIPK1 WRNIP1	6.27e-04	622	81	7	14574404
Pubmed	Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis.	GCM2 LY75	6.29e-04	16	81	2	25053428
Pubmed	Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex.	RELN FOXP2	6.29e-04	16	81	2	26235615
Pubmed	Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects.	COL3A1 SIPA1L1	6.29e-04	16	81	2	36092713
Pubmed	Maternal immunoglobulins are distributed in the offspring's brain to support the maintenance of cortical interneurons in the postnatal period.	RELN PDGFRB	6.29e-04	16	81	2	38750507
Pubmed	The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate.	RELN FOXP2	6.29e-04	16	81	2	14758363
Pubmed	Extracellular matrix proteins expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line.	COL11A1 LOX	6.29e-04	16	81	2	24804215
Pubmed	Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling.	COL3A1 PDGFRB	7.12e-04	17	81	2	21512159
Pubmed	Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice.	RELN FOXP2	7.12e-04	17	81	2	37590085
Pubmed	Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling.	RELN FOXP2	7.12e-04	17	81	2	20620871
Pubmed	The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors.	COL3A1 PDGFRB	7.12e-04	17	81	2	22573622
Pubmed	Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex.	RELN FOXP2	7.12e-04	17	81	2	21315259
Pubmed	PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis.	COL3A1 BMP10	8.00e-04	18	81	2	21511879
Pubmed	Muscle composition is regulated by a Lox-TGFβ feedback loop.	COL3A1 LOX	8.93e-04	19	81	2	25715398
Pubmed	Analysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypes.	MUC15 SLC5A12	8.93e-04	19	81	2	19474196
Pubmed	Pericytes are required for blood-brain barrier integrity during embryogenesis.	COL3A1 PDGFRB	8.93e-04	19	81	2	20944625
Pubmed	Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse.	GCM2 PDGFRB	8.93e-04	19	81	2	25249461
Pubmed	Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools.	RELN FOXP2	8.93e-04	19	81	2	21666133
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FARSA RELN SORBS2 BRD2 SUPT5H PCDH15 PRMT1 RSRC2 RBM17	9.27e-04	1082	81	9	38697112
Pubmed	The protein tyrosine kinase family of the human genome.	DDR1 PDGFRB INSRR	9.78e-04	83	81	3	11114734
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SORBS2 UNC45A	9.91e-04	20	81	2	21689717
Pubmed	ERK1 and ERK2 are required for radial glial maintenance and cortical lamination.	RELN FOXP2	1.09e-03	21	81	2	20825492
Pubmed	Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation.	RELN FOXP2	1.09e-03	21	81	2	23404109
Pubmed	Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis.	PRMT1 RBM17	1.09e-03	21	81	2	30179224
Interaction	TIGIT interactions	DDR1 PTPRD NECTIN3 ACVR2A	3.22e-06	26	80	4	int:TIGIT
Cytoband	1q21-q23	INSRR B4GALT3	2.37e-04	13	81	2	1q21-q23
Cytoband	6p25.2	RIPK1 WRNIP1	6.94e-04	22	81	2	6p25.2
Cytoband	8q21.3	OTUD6B MMP16	1.21e-03	29	81	2	8q21.3
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	MAG NECTIN3 CD200R1	1.52e-04	40	47	3	592
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	DDR1 PDGFRB INSRR	1.52e-04	40	47	3	321
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MAG PTPRD PDGFRB NECTIN3	8.02e-04	161	47	4	593
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	DDR1 LILRA1 PDGFRB NECTIN3 LY75	3.47e-03	394	47	5	471
Coexpression	HALLMARK_UV_RESPONSE_DN	COL3A1 COL11A1 PDGFRB SIPA1L1 ACVR2A MMP16	5.73e-06	144	81	6	M5942
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	TXNRD1 ILRUN RHOQ OSBP RELN BRD2 LOX AHR KLF3 ACVR2A SIM2 RSRC2	8.12e-06	822	81	12	M6782
Coexpression	GSE6259_33D1_POS_DC_VS_BCELL_UP	RIPK1 MGST3 ACTR5 SHMT1 KLF3 NECTIN3	8.74e-06	155	81	6	M6751
Coexpression	DING_LUNG_CANCER_BY_MUTATION_RATE	DDR1 PTPRD INSRR	3.12e-05	20	81	3	M1189
Coexpression	GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN	RHOQ DDR1 RELN GCM2 KLF3 ACVR2A	3.69e-05	200	81	6	M5128
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_30H_UP	TXNRD1 COL3A1 MAG SRM RPGR B4GALT3	3.69e-05	200	81	6	M9649
Coexpression	CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN	RELN PTPRD FOXP2 SIPA1L1 SLC6A20 AHR SHMT1 NCBP3	3.78e-05	407	81	8	M2214
Coexpression	ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE	COL3A1 COL11A1 PDGFRB LOX	4.67e-05	64	81	4	M2572
Coexpression	DANG_REGULATED_BY_MYC_UP	TXNRD1 TXNL4A SRM SHMT1	5.93e-05	68	81	4	M18501
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	SORBS2 PTPRD SIPA1L1 PCDH15 SLC5A12 ACMSD	6.43e-05	221	81	6	M39222
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB LOX PCDH15 ACVR2A	1.31e-06	190	81	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB LOX PCDH15 LRRTM3	1.39e-06	192	81	6	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	RHOQ COL11A1 HEG1 LOX TKTL1 RPGR	1.61e-06	197	81	6	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	RHOQ COL11A1 HEG1 LOX TKTL1 RPGR	1.61e-06	197	81	6	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 FOXP2 PDGFRB LOX MMP16	1.66e-06	198	81	6	55d2ed345101bec4b73f1242ba8c4d73073b7e88
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PTPRD PDGFRB LOX MMP16	1.66e-06	198	81	6	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 FOXP2 PDGFRB LOX MMP16	1.66e-06	198	81	6	8602a518b5913625b1dd3cbc3c7e6efde0d5d942
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PTPRD PDGFRB LOX MMP16	1.71e-06	199	81	6	7b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PTPRD PDGFRB LOX MMP16	1.71e-06	199	81	6	f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LRRTM2 PCDH15 ZC3H12B LRRTM3 MMP16	9.44e-06	155	81	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	VPS13D PTPRD PCDH15 DHTKD1 RBM17	1.13e-05	161	81	5	347edb0de10850b7d16c40945751033289289c9b
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBPL2 DDR1 RPGR PFKFB1 LY75	1.39e-05	168	81	5	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 PTPRD GCM2 LOX DHTKD1	1.47e-05	170	81	5	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAG RELN SORBS2 MLIP AHR	1.60e-05	173	81	5	922356a5b4c84607318ac24d7caa2e235b72b066
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL11A1 SORBS2 SIM2 MMP16 CC2D2B	1.79e-05	177	81	5	b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	COL3A1 COL11A1 HEG1 PDGFRB LOX	1.84e-05	178	81	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL11A1 MLIP PDGFRB LOX MMP16	1.84e-05	178	81	5	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HEG1 SORBS2 MLIP RPGR CC2D2B	1.94e-05	180	81	5	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	wk_15-18-Mesenchymal-Chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MAG COL11A1 SORBS2 FOXP2 SIM2	1.99e-05	181	81	5	8950844b3e65c7028d80da5787ae2ce509c3d52d
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high\|Trachea / Age, Tissue, Lineage and Cell class	COL3A1 COL11A1 PDGFRB LOX SIM2	2.05e-05	182	81	5	354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL11A1 SORBS2 LCTL SIPA1L1 MMP16	2.05e-05	182	81	5	00a148b1e499bf16325491536d187d4dd6b70c06
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 MLIP SIPA1L1 NECTIN3 RFX2	2.10e-05	183	81	5	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 MLIP SIPA1L1 NECTIN3 RFX2	2.16e-05	184	81	5	30fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 MLIP SIPA1L1 NECTIN3 RFX2	2.16e-05	184	81	5	96926efa220f03d0787322c9519bb9e8f64f74d0
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PDGFRB NECTIN3 MMP16	2.39e-05	188	81	5	ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	COL3A1 COL11A1 PDGFRB SIM2 MMP16	2.39e-05	188	81	5	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	Mesenchymal_cells-Osteoblasts\|World / Lineage and Cell class	COL11A1 SORBS2 MLIP LOX MMP16	2.39e-05	188	81	5	89f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD LOX PCDH15 LRRTM3	2.45e-05	189	81	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB PCDH15 ACVR2A	2.45e-05	189	81	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL11A1 LRRTM2 PCDH15 LRRTM3 MMP16	2.52e-05	190	81	5	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB LOX PCDH15	2.52e-05	190	81	5	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB LOX PCDH15	2.52e-05	190	81	5	d60395739458d7f47a3350ade751fe3819500320
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB LOX PCDH15	2.58e-05	191	81	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB LOX PCDH15	2.65e-05	192	81	5	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD LOX PCDH15 LRRTM3	2.65e-05	192	81	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB LOX PCDH15	2.65e-05	192	81	5	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 PTPRD PDGFRB PCDH15 ACVR2A	2.65e-05	192	81	5	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	RELN ACTR5 ACVR2A PAIP1 B4GALT3	2.85e-05	195	81	5	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 LCTL FOXP2 MMP16	2.85e-05	195	81	5	30ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL11A1 LRRTM2 PCDH15 LRRTM3 MMP16	2.92e-05	196	81	5	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL11A1 LRRTM2 PCDH15 LRRTM3 MMP16	2.92e-05	196	81	5	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 RELN COL11A1 PDGFRB LOX	2.92e-05	196	81	5	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 LCTL LOX MMP16	2.99e-05	197	81	5	2f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PDGFRB LOX MMP16	2.99e-05	197	81	5	63b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRD FOXP2 WRNIP1 KYAT3 PRMT1	2.99e-05	197	81	5	789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PDGFRB LOX MMP16	2.99e-05	197	81	5	fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNRD1 COL11A1 PTPRD RIPK1 LOX	2.99e-05	197	81	5	cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 COL11A1 PTPRD PDGFRB LOX	3.07e-05	198	81	5	9541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PTPRD PDGFRB MMP16	3.07e-05	198	81	5	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PTPRD LOX MMP16	3.07e-05	198	81	5	6a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PDGFRB LOX MMP16	3.22e-05	200	81	5	780d47f8eff630020dfae32218de495a7e9dbad6
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL3A1 COL11A1 PTPRD PDGFRB MMP16	3.22e-05	200	81	5	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PDGFRB LOX MMP16	3.22e-05	200	81	5	28dd127787a57276253548d1f030814b1af64481
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK---L2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SORBS2 MLIP SIPA1L1 NECTIN3 RFX2	3.22e-05	200	81	5	6ebdae4438bc64c6620416f64a7e22fbca2664bf
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SORBS2 MLIP SIPA1L1 NECTIN3 RFX2	3.22e-05	200	81	5	081ca331b56f85167acfc73af9d2e91f398f8c4d
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PTPRD LOX MMP16	3.22e-05	200	81	5	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SORBS2 MLIP SIPA1L1 NECTIN3 RFX2	3.22e-05	200	81	5	66e2f3e2e9063f17b47621120eb6009405f69e7e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial-Astrocyte\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	COL11A1 PDGFRB PCDH15 TKTL1 LRRTM3	3.22e-05	200	81	5	7205e742ad796d548761839d92a4794ee8f17629
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL11A1 PTPRD LOX MMP16	3.22e-05	200	81	5	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-LTK\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SORBS2 MLIP SIPA1L1 NECTIN3 RFX2	3.22e-05	200	81	5	940892bea41fde567f138a896d151acccef03a6a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	COL11A1 PDGFRB PCDH15 TKTL1 LRRTM3	3.22e-05	200	81	5	25b573f4427ecafe050ca90bea459f1b25b451cf
ToppCell	RV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ASB18 SORBS2 MLIP LRRTM3	7.29e-05	122	81	4	1cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	VPS13D FOXP2 PCDH15 RBM17	1.08e-04	135	81	4	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	COL3A1 HEG1 PTPRD LOX	1.58e-04	149	81	4	3904f8ce9078de238600ceceee0116af52256a1c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PCDH15 ELOVL3 LRRTM3 MMP16	1.75e-04	153	81	4	61fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	COL3A1 PTPRD LOX KYAT3	2.02e-04	159	81	4	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SORBS2 LTO1 NECTIN3 NCBP3	2.22e-04	163	81	4	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAG RELN MLIP GCM2	2.28e-04	164	81	4	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 LOX INSRR MMP16	2.33e-04	165	81	4	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 LOX INSRR MMP16	2.44e-04	167	81	4	fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 RELN LOX ACVR2A	2.49e-04	168	81	4	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRD PCDH15 SLC5A12 ACMSD	2.49e-04	168	81	4	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 RELN LOX ACVR2A	2.49e-04	168	81	4	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL11A1 SORBS2 SIM2 MMP16	2.55e-04	169	81	4	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ASB18 SORBS2 MLIP LRRTM3	2.61e-04	170	81	4	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 SORBS2 OTUD6B MMP16	2.61e-04	170	81	4	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SORBS2 MLIP LCTL ACMSD	2.61e-04	170	81	4	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 SORBS2 OTUD6B MMP16	2.61e-04	170	81	4	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SORBS2 MLIP LCTL ACMSD	2.61e-04	170	81	4	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD16\|GI_small-bowel / Manually curated celltypes from each tissue	PDGFRB KLF3 TKTL1 SIM2	2.67e-04	171	81	4	1ee505b91f15191d294a5d491ecdf154c08b8622
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ASB18 COL11A1 FOXP2 ACVR2A	2.67e-04	171	81	4	9e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRD PCDH15 SLC5A12 ACMSD	2.67e-04	171	81	4	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBPL2 DDR1 ZC3H12B CD200R1	2.67e-04	171	81	4	2dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBPL2 DDR1 ZC3H12B CD200R1	2.67e-04	171	81	4	2aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LCTL PCDH15 AHR MMP16	2.67e-04	171	81	4	3112d15f2a28cf4a71992db4971d960716dc1264
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL11A1 PDGFRB MMP16	2.73e-04	172	81	4	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 COL11A1 PDGFRB MMP16	2.73e-04	172	81	4	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	droplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBPL2 DDR1 ZC3H12B CD200R1	2.79e-04	173	81	4	8fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCell	droplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBPL2 DDR1 ZC3H12B CD200R1	2.79e-04	173	81	4	f663571aaae2365660a8b526c355f4bd1a124a74
ToppCell	Caecum-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	LTO1 TLR5 ACVR2A	2.82e-04	70	81	3	05f8fc648641b9db50c2ae20d6246b52869957cf
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 MLIP PTPRD MUC15	2.85e-04	174	81	4	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ASB18 COL11A1 FOXP2 ACVR2A	2.85e-04	174	81	4	2947e5906b172d149412fa4e77476fce4ea695d2
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MAG COL11A1 LCTL FOXP2	2.91e-04	175	81	4	a84965d28438a4228d841b357c2cd75cf4b59a63
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ASB18 SORBS2 MLIP LRRTM3	2.98e-04	176	81	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	ASK452-Endothelial-Lymphatic\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	RELN ACTR5 ACVR2A PAIP1	2.98e-04	176	81	4	b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 PTPRD PCDH15 ZC3H12B	3.04e-04	177	81	4	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL11A1 SORBS2 MLIP FOXP2	3.04e-04	177	81	4	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 PTPRD PCDH15 ZC3H12B	3.04e-04	177	81	4	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	COL3A1 PTPRD PDGFRB LOX	3.17e-04	179	81	4	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_8\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	JADE2 SIPA1L1 ELOVL3 CD200R1	3.17e-04	179	81	4	163f5430d72ea0c1b239ea5d21e53be536636d3d
Disease	interleukin-6 measurement, response to cytokine	VPS13D SORBS2	6.90e-06	2	78	2	EFO_0004810, GO_0034097
Disease	interleukin-6 measurement, response to corticosteroid, response to cytokine	VPS13D SORBS2	6.90e-06	2	78	2	EFO_0004810, GO_0031960, GO_0034097
Disease	Weight Gain	VPS13D SORBS2 SIPA1L1 AHR	1.58e-04	102	78	4	C0043094
Disease	coiled-coil domain-containing protein 80 measurement	NECTIN3 CD200R1	1.91e-04	8	78	2	EFO_0020268
Disease	disease recurrence, unipolar depression, bipolar disorder, schizophrenia	FOXP2 NCBP3	1.91e-04	8	78	2	EFO_0003761, EFO_0004952, MONDO_0004985, MONDO_0005090
Disease	Gastric Adenocarcinoma	BRD2 PDGFRB ACVR2A	2.33e-04	45	78	3	C0278701
Disease	Ehlers-Danlos syndrome (is_implicated_in)	COL3A1 LOX	2.45e-04	9	78	2	DOID:13359 (is_implicated_in)
Disease	Aortic Valve Insufficiency	COL3A1 LOX	3.74e-04	11	78	2	C0003504
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL3A1 COL11A1 LOX	3.78e-04	53	78	3	C4707243
Disease	Liver Cirrhosis, Experimental	COL3A1 RHOQ PTPRD PDGFRB LOX DHTKD1 CD200R1 SNAP29	1.01e-03	774	78	8	C0023893
Disease	QRS duration	ILRUN DDR1 COL11A1 PTPRD SIPA1L1	1.18e-03	298	78	5	EFO_0005055
Disease	unipolar depression, bipolar disorder, schizophrenia	FOXP2 NCBP3	1.27e-03	20	78	2	EFO_0003761, MONDO_0004985, MONDO_0005090
Disease	Cleft Palate	COL11A1 TXNL4A SIM2	1.31e-03	81	78	3	C0008925
Disease	short-term memory	SORBS2 PTPRD PCDH15	1.40e-03	83	78	3	EFO_0004335
Disease	Back pain	ILRUN COL11A1 ACVR2A	1.61e-03	87	78	3	HP_0003418
Disease	autism spectrum disorder, schizophrenia	DDR1 BRD2 ACTR5 SIPA1L1 MMP16	1.77e-03	327	78	5	EFO_0003756, MONDO_0005090
Disease	Left Ventricular Hypertrophy	COL3A1 AHR	1.99e-03	25	78	2	C0149721
Disease	Adenocarcinoma of lung (disorder)	INSRR SRM AHR SHMT1	2.20e-03	206	78	4	C0152013
Disease	Schizophrenia	COL3A1 MAG DDR1 RELN FOXP2 PDGFRB SHMT1 SNAP29	2.30e-03	883	78	8	C0036341
Disease	triglyceride measurement, response to escitalopram, response to citalopram	COL11A1 SORBS2	2.32e-03	27	78	2	EFO_0004530, EFO_0006329, EFO_0007871
Disease	susceptibility to rheumatic fever measurement	RELN PTPRD	2.49e-03	28	78	2	EFO_0008416
Disease	glucose metabolism disease (implicated_via_orthology)	TLR5 INSRR	2.49e-03	28	78	2	DOID:4194 (implicated_via_orthology)
Disease	Liver Cirrhosis	COL3A1 LOX AHR	2.60e-03	103	78	3	C0023890

Protein segments in the cluster

Peptide	Gene	Start	Entry
PYKSEMDSMPYTQNF	AHR	686	P35869
VSYKNYEFFLPDNME	PFKFB1	86	P16118
TPDQYLKMNGFPNEY	B4GALT3	241	O60512
NEKFSYFPEMEVTQP	ACVR2A	111	P27037
KPTNTQAYSGDYMEP	DDR1	536	Q08345
NPMNPKKYLGSFYTD	ACMSD	251	Q8TDX5
PDYYENNVHKMQLPF	ACTR5	266	Q9H9F9
NELDEPFYTNPIMYK	DHTKD1	436	Q96HY7
PNNPEYSDLMESVTY	CC2D2B	681	Q6DHV5
KPNAEDMTSKDYYFD	PRMT1	41	Q99873
VYEPNPFSKYLEDNS	MLIP	351	Q5VWP3
QEAMDPVSVSYPSNY	KLF3	11	P57682
SNMSDQGPYNEYEPT	LRRTM2	476	O43300
LQFEGYASMDVKYPP	MAG	226	P20916
YYNPTLNDSAMPESE	MUC15	301	Q8N387
MSNSDYLPDYPLNSD	ASB18	1	Q6ZVZ8
EMSYDNNPFIKTLYD	COL11A1	1741	P12107
MKIPDSYQLSPDDYY	JADE2	61	Q9NQC1
ANPIYAGDYPQVMKD	LCTL	291	Q6UWM7
PTHYMPYNESVSFED	ENPP5	151	Q9UJA9
PMSSEIAPNYEFYKN	FOXP2	486	O15409
MSTQDVFSYFKEYPP	NCBP3	136	Q53F19
DYKEEYNTTLPQFMP	LY75	1386	O60449
DEMQPYASYTEKNNP	CD200R1	286	Q8TD46
KSGDFQMSPYAEYPK	HEG1	1286	Q9ULI3
YKVEYPIMYSTDPEN	MGST3	36	O14880
LPKNAENMYYFSELA	OSBP	686	P22059
PENDPNYFMNEPTFY	PAIP1	391	Q9H074
PQNFYEKPAFDYPMN	RELN	1236	P78509
LDENNQSPYFTMPSY	PCDH15	386	Q96QU1
PNTGDMYTPEEFQKY	OTUD6B	201	Q8N6M0
AYYDFESPNISVPSM	ILRUN	61	Q9H6K1
PPEYMLELYNKFATD	BMP10	81	O95393
QPYNFELSKDMRPFF	ELOVL3	16	Q9HB03
MGYFLPDDYKFSVPN	C3orf20	821	Q8ND61
MVGDDPYNPYKYSDD	LOX	166	P28300
IGMIQKFPYDDPTYD	LTO1	86	Q8WV07
VNPEYFSASDMYVPD	INSRR	956	P14616
QPDGYEQTYAEMPKA	ITPA	156	Q9BY32
FAPYYGDEPMDFKIN	COL3A1	1216	P02461
DPDLSDMKNNEPYDY	KYAT3	381	Q6YP21
IESSNYMAPYDNYVP	PDGFRB	766	P09619
PENYNSAMPFKILYD	PTPRD	1041	P23468
FFESMPYKVNPDTGY	SHMT1	166	P34896
YNENPKGYMLDDADS	RPGR	916	Q92834
DYFSFNFPNSPVKME	RSBN1L	416	Q6PCB5
LMSYANDAFPEEYVP	RHOQ	26	P17081
SYYNPAAVNPMKFAE	RSRC2	316	Q7L4I2
KPAYNPYTEPSMEVF	FARSA	406	Q9Y285
SIHEYPKYQAEFPMS	LILRA1	371	O75019
QMTPSTQEFYVDYKP	LRRTM3	471	Q86VH5
EPQMYAPSSTASYFE	RFX2	96	P48378
YQAYQPPAMKYSDSV	GCM2	391	O75603
MSAYPKSYNPFDDDG	SNAP29	1	O95721
EKPDEMKENGSPYNY	SIPA1L1	521	O43166
YPPQQYSSFQMDKLE	SIM2	386	Q14190
TPAMYNTDQFSPYAA	SUPT5H	881	O00267
YYMAPEHLNDVNAKP	RIPK1	191	Q13546
NFKMPFPIDQDFYVS	SGSH	391	P51688
ASAYPSKYSEMFPQI	SLC6A20	341	Q9NP91
PDDDTDMYNTPYTYN	SORBS2	111	O94875
MFSNCYKYNPPDHDV	BRD2	421	P25440
MNGPEDLPKSYDYDL	TXNRD1	151	Q16881
KTYPYNETKESFDPN	ZNF189	426	O75820
PFYQYMETDNFKLPN	MMP16	266	P51512
LADEYDPMFPNDYEK	RBM17	96	Q96I25
NTYNKFPYPTMSEIT	ZHX1	301	Q9UKY1
DPMGPAESLFKESYY	SRM	176	P19623
TPISYAEQYPKFESM	ZC3H12B	526	Q5HYM0
KYNPMYSEPVDQEYL	WRNIP1	636	Q96S55
VPDFNKMYELYDPCT	TXNL4A	66	P83876
DHPQGTEPDMYKYDA	TLR5	681	O60602
YDPKDKSYNNMAFET	SLC5A12	601	Q1EHB4
YLEDMKTYFGAEPQP	SERPINB10	126	P48595
FFYIMRYKQSDPENP	TKTL1	61	P51854
CTNSYDYEEPDPKMV	UNC45A	596	Q9H3U1
SPTFKEFIPYMANEY	UGGT1	1296	Q9NYU2
PYDMYILNASNPDTA	TBPL2	66	Q6SJ96
KENYPDYMPSNIFSD	VPS13D	3151	Q5THJ4
YMNTSVQEPPLDYSF	LRRC51	6	Q96E66
GDYFAKNYIPPSDMQ	NECTIN3	436	Q9NQS3