Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR1 FGFR3 FGFR2

9.10e-075913GO:0005007
GeneOntologyMolecularFunctionfibroblast growth factor binding

FGFR1 FGFR3 FGFR2

2.47e-0427913GO:0017134
GeneOntologyBiologicalProcessbranching involved in salivary gland morphogenesis

HGF SEMA3C FGFR1 FGFR2

5.86e-0628884GO:0060445
GeneOntologyBiologicalProcessfibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development

FGFR1 FGFR2

1.80e-052882GO:0035607
GeneOntologyBiologicalProcesssalivary gland morphogenesis

HGF SEMA3C FGFR1 FGFR2

2.04e-0538884GO:0007435
GeneOntologyBiologicalProcesspositive regulation of phospholipase activity

FGFR1 FGFR3 FGFR2

2.64e-0514883GO:0010518
GeneOntologyBiologicalProcesssalivary gland development

HGF SEMA3C FGFR1 FGFR2

3.36e-0543884GO:0007431
GeneOntologyBiologicalProcessactivation of NF-kappaB-inducing kinase activity

TRAF4 TRAF6 TLR1

4.89e-0517883GO:0007250
GeneOntologyBiologicalProcessfibroblast growth factor receptor apoptotic signaling pathway

FGFR3 FGFR2

5.38e-053882GO:1902178
GeneOntologyBiologicalProcessventricular zone neuroblast division

FGFR1 FGFR2

5.38e-053882GO:0021847
GeneOntologyBiologicalProcessorbitofrontal cortex development

FGFR1 FGFR2

5.38e-053882GO:0021769
GeneOntologyBiologicalProcessexocrine system development

HGF SEMA3C FGFR1 FGFR2

1.03e-0457884GO:0035272
GeneOntologyBiologicalProcessregulation of phospholipase activity

FGFR1 FGFR3 FGFR2

1.09e-0422883GO:0010517
GeneOntologyBiologicalProcesspositive regulation of lipase activity

FGFR1 FGFR3 FGFR2

1.61e-0425883GO:0060193
GeneOntologyBiologicalProcesspositive regulation of protein oligomerization

ABCA3 ZDHHC1

1.78e-045882GO:0032461
GeneOntologyBiologicalProcessregulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling

HGF FGFR1

1.78e-045882GO:0060665
GeneOntologyBiologicalProcessphosphatidylinositol 3-kinase/protein kinase B signal transduction

HGF PIK3C2A MAZ MKRN2 VAV3 FGFR1 FGFR3 CBL

2.28e-04382888GO:0043491
GeneOntologyBiologicalProcessforebrain ventricular zone progenitor cell division

FGFR1 FGFR2

2.67e-046882GO:0021869
GeneOntologyBiologicalProcesspositive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

FGFR1 FGFR3

2.67e-046882GO:0090080
GeneOntologyBiologicalProcesspositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

HGF MAZ VAV3 FGFR1 FGFR3 CBL

3.35e-04217886GO:0051897
GeneOntologyBiologicalProcessforebrain neuroblast division

FGFR1 FGFR2

3.73e-047882GO:0021873
GeneOntologyBiologicalProcessregulation of protein oligomerization

ABCA3 ZDHHC1

3.73e-047882GO:0032459
GeneOntologyCellularComponentgrowth cone

LIMK1 RASGRF1 MYO5A NGEF CBL PREX1 NIN

8.49e-05245897GO:0030426
GeneOntologyCellularComponentsite of polarized growth

LIMK1 RASGRF1 MYO5A NGEF CBL PREX1 NIN

1.04e-04253897GO:0030427
HumanPhenoShort middle phalanx of toe

FGFR1 FGFR3 FGFR2

2.46e-065333HP:0003795
HumanPhenoCloverleaf skull

FGFR1 FGFR3 FGFR2

1.36e-058333HP:0002676
HumanPhenoAbnormality of the middle phalanges of the toes

FGFR1 FGFR3 FGFR2

3.95e-0511333HP:0010183
HumanPhenoBroad proximal phalanx of the hallux

FGFR1 FGFR2

4.07e-052332HP:0010086
HumanPhenoCalcaneonavicular fusion

FGFR1 FGFR2

4.07e-052332HP:0008122
HumanPheno3-4 toe cutaneous syndactyly

FGFR1 FGFR2

4.07e-052332HP:6000648
HumanPhenoBroad middle phalanges of the toes

FGFR1 FGFR2

4.07e-052332HP:0010195
HumanPhenoTracheal cartilaginous sleeve

FGFR1 FGFR2

4.07e-052332HP:0005347
HumanPhenoAbnormality of the distal phalanx of the hallux

FGFR1 FGFR3 FGFR2

5.24e-0512333HP:0010053
HumanPhenoBroad distal phalanx of the hallux

FGFR1 FGFR2

1.22e-043332HP:0010077
HumanPhenoDeviation of the hallux

LIMK1 AEBP1 FGFR1 FGFR3 FGFR2

2.22e-0488335HP:0010051
HumanPhenoDuplication of the distal phalanx of the hallux

FGFR3 FGFR2

2.42e-044332HP:0010084
HumanPhenoDuplication of distal phalanx of toe

FGFR3 FGFR2

2.42e-044332HP:0010193
HumanPhenoHypoplasia of the lacrimal punctum

FGFR3 FGFR2

2.42e-044332HP:0007892
HumanPhenoAnomalous tracheal cartilage

FGFR1 FGFR2

2.42e-044332HP:0004468
HumanPhenoLacrimal gland aplasia

FGFR3 FGFR2

2.42e-044332HP:0007656
HumanPhenoSynostosis of joints

LIMK1 AEBP1 ASH1L FGFR1 FGFR3 FGFR2 CBL

3.32e-04212337HP:0100240
HumanPhenoHypoplasia of the middle phalanges of the hand

FGFR1 FGFR3 FGFR2 NIN

3.95e-0455334HP:0010240
HumanPhenoShort middle phalanx of finger

FGFR1 FGFR3 FGFR2 NIN

3.95e-0455334HP:0005819
HumanPhenoBroad distal phalanx of the toes

FGFR1 FGFR2

4.02e-045332HP:0010186
HumanPhenoIncreased corneal thickness

FGFR3 FGFR2

4.02e-045332HP:0011487
HumanPhenoShort first metatarsal

FGFR1 FGFR2

4.02e-045332HP:0010105
HumanPhenoDecreased corneal sensation

FGFR3 FGFR2

4.02e-045332HP:0012155
HumanPhenoHallux varus

FGFR1 FGFR2

4.02e-045332HP:0008080
MousePhenopremature facial suture closure

FGFR1 FGFR2

2.47e-052702MP:0030390
MousePhenoabnormal tail morphology

PRAMEF33 TRAF4 TRAF6 MYO5A AEBP1 PA2G4 FGFR1 FGFR3 FGFR2 CBL

3.00e-054037010MP:0002111
MousePhenohearing/vestibular/ear phenotype

USP53 HGF HARS2 PRAMEF33 TRAF6 MYO5A SCMH1 MAZ MKRN2 FGFR1 FGFR3 FGFR2 CBL OPA1 NIN

3.28e-059057015MP:0005377
MousePhenopremature intramembranous bone ossification

FGFR1 FGFR3 FGFR2

4.21e-0514703MP:0003418
MousePhenopremature cranial suture closure

FGFR1 FGFR3 FGFR2

4.21e-0514703MP:0000081
MousePhenopremature craniofacial suture closure

FGFR1 FGFR3 FGFR2

4.21e-0514703MP:0030435
MousePhenolong incisors

FGFR1 FGFR3 FGFR2

6.43e-0516703MP:0004831
MousePhenomacrodontia

FGFR1 FGFR3 FGFR2

6.43e-0516703MP:0030091
MousePhenoabnormal organ of Corti supporting cell morphology

USP53 HGF FGFR1 FGFR3

6.73e-0544704MP:0004300
MousePhenoabnormal skin pigmentation

TRAF6 MYO5A ADAMTS20 FGFR2 CBL

7.32e-0587705MP:0002095
MousePhenomidface hypoplasia

FGFR1 FGFR3 FGFR2

7.78e-0517703MP:0012085
MousePhenodecreased endocochlear potential

USP53 HGF FGFR1

9.30e-0518703MP:0004411
MousePhenoface hypoplasia

FGFR1 FGFR3 FGFR2

1.10e-0419703MP:0030065
MousePhenoabnormal facial suture morphology

FGFR1 FGFR2

1.47e-044702MP:0030230
MousePhenopremature metopic suture closure

FGFR1 FGFR3

1.47e-044702MP:0030367
MousePhenofused tracheal cartilage rings

TRAF4 FGFR2

1.47e-044702MP:0004552
MousePhenoabnormal hearing electrophysiology

USP53 HGF HARS2 PRAMEF33 SCMH1 MAZ MKRN2 FGFR1 FGFR3 OPA1 NIN

1.64e-045947011MP:0006335
MousePhenoabnormal endocochlear potential

USP53 HGF FGFR1

2.26e-0424703MP:0002630
MousePhenoabnormal cochlear endolymph physiology

USP53 HGF FGFR1

2.26e-0424703MP:0006390
MousePhenoabnormal sternocostal joint morphology

TRAF4 SCMH1 ASH1L FGFR1

2.43e-0461704MP:0008148
MousePhenoabnormal endolymph physiology

USP53 HGF FGFR1

2.56e-0425703MP:0004885
MousePhenopremature bone ossification

FGFR1 FGFR3 FGFR2

2.88e-0426703MP:0003416
MousePhenoabnormal hearing physiology

USP53 HGF HARS2 PRAMEF33 SCMH1 MAZ MKRN2 FGFR1 FGFR3 OPA1 NIN

3.26e-046437011MP:0001963
MousePhenoabnormal midface morphology

FGFR1 FGFR3 FGFR2

3.60e-0428703MP:0030095
MousePhenopremature coronal suture closure

FGFR1 FGFR2

3.66e-046702MP:0030350
MousePhenoabnormal cranial synchondrosis

FGFR3 FGFR2

3.66e-046702MP:0030443
MousePhenoocular hypertelorism

FGFR1 FGFR3 FGFR2

4.00e-0429703MP:0001300
MousePhenoabnormal stapes morphology

TRAF6 FGFR1 FGFR3

4.89e-0431703MP:0005107
MousePhenoabnormal ear physiology

USP53 HGF HARS2 PRAMEF33 SCMH1 MAZ MKRN2 FGFR1 FGFR3 OPA1 NIN

5.50e-046847011MP:0003878
MousePhenoabnormal auditory brainstem response

USP53 HARS2 PRAMEF33 SCMH1 MAZ MKRN2 FGFR1 FGFR3 OPA1 NIN

5.57e-045767010MP:0004738
MousePhenoabnormal neural crest cell migration

SEMA3C ADAMTS20 FGFR1

6.44e-0434703MP:0002950
DomainFGF_rcpt_fam

FGFR1 FGFR3 FGFR2

3.63e-074853IPR016248
DomainGDS_CDC24_CS

RASGRF1 NGEF VAV3 PREX1

2.91e-0539854IPR001331
Domainzf-C3HC4

TRIM46 TRAF4 TRAF6 MKRN2 VPS8 TRIM27 CBL

7.06e-05223857PF00097
DomainZnf_RING_CS

TRIM46 TRAF4 TRAF6 MKRN2 TRIM27 CBL

9.98e-05163856IPR017907
DomainZnf_C3HC4_RING-type

TRIM46 TRAF4 TRAF6 MKRN2 TRIM27 CBL

1.34e-04172856IPR018957
DomainDH_1

RASGRF1 NGEF VAV3 PREX1

1.94e-0463854PS00741
Domain-

TRIM46 RMND5B TRAF4 TRAF6 MKRN2 VPS8 ASH1L TRIM27 CBL

2.02e-044498593.30.40.10
DomainIg_I-set

SEMA3C SDK2 CADM1 FGFR1 FGFR3 FGFR2

2.30e-04190856IPR013098
DomainI-set

SEMA3C SDK2 CADM1 FGFR1 FGFR3 FGFR2

2.30e-04190856PF07679
DomainZnf_RING/FYVE/PHD

TRIM46 RMND5B TRAF4 TRAF6 MKRN2 VPS8 ASH1L TRIM27 CBL

2.38e-04459859IPR013083
DomainRhoGEF

RASGRF1 NGEF VAV3 PREX1

2.61e-0468854SM00325
DomainRhoGEF

RASGRF1 NGEF VAV3 PREX1

2.91e-0470854PF00621
DomainDH_2

RASGRF1 NGEF VAV3 PREX1

2.91e-0470854PS50010
DomainTNF_rcpt--assoc_TRAF

TRAF4 TRAF6

3.03e-046852IPR012227
DomainDH-domain

RASGRF1 NGEF VAV3 PREX1

3.08e-0471854IPR000219
Domain-

RASGRF1 NGEF VAV3 PREX1

3.08e-04718541.20.900.10
DomainZF_RING_1

TRIM46 TRAF4 TRAF6 MKRN2 VPS8 TRIM27 CBL

3.63e-04291857PS00518
DomainZF_RING_2

TRIM46 TRAF4 TRAF6 MKRN2 VPS8 TRIM27 CBL

4.18e-04298857PS50089
DomainRING

TRIM46 TRAF4 TRAF6 MKRN2 VPS8 TRIM27 CBL

4.81e-04305857SM00184
Domainzf-TRAF

TRAF4 TRAF6

5.63e-048852PF02176
DomainZnf_RING

TRIM46 TRAF4 TRAF6 MKRN2 VPS8 TRIM27 CBL

7.13e-04326857IPR001841
Domain-

FBXW10B SEMA3C FBXW10 AHI1 RBBP5 VPS8 BRWD1

8.07e-043338572.130.10.10
DomainWD40/YVTN_repeat-like_dom

FBXW10B SEMA3C FBXW10 AHI1 RBBP5 VPS8 BRWD1

8.36e-04335857IPR015943
DomainMATH/TRAF_dom

TRAF4 TRAF6

1.31e-0312852IPR002083
DomainMATH

TRAF4 TRAF6

1.31e-0312852PS50144
DomainMATH

TRAF4 TRAF6

1.31e-0312852SM00061
DomainZnf_TRAF

TRAF4 TRAF6

1.31e-0312852IPR001293
DomainMATH

TRAF4 TRAF6

1.31e-0312852PF00917
DomainWD40_repeat

FBXW10B FBXW10 AHI1 RBBP5 VPS8 BRWD1

1.51e-03272856IPR001680
DomainZF_TRAF

TRAF4 TRAF6

1.55e-0313852PS50145
DomainWD_REPEATS_1

FBXW10B FBXW10 AHI1 RBBP5 VPS8 BRWD1

1.69e-03278856PS00678
DomainWD_REPEATS_2

FBXW10B FBXW10 AHI1 RBBP5 VPS8 BRWD1

1.72e-03279856PS50082
DomainWD_REPEATS_REGION

FBXW10B FBXW10 AHI1 RBBP5 VPS8 BRWD1

1.72e-03279856PS50294
Domain-

TRAF4 TRAF6

1.80e-03148523.90.890.10
Domain-

TRAF4 TRAF6

1.80e-03148522.60.210.10
DomainLRR_6

NLRP9 CARMIL1 NLRP5

2.01e-0355853PF13516
DomainWD40_repeat_dom

FBXW10B FBXW10 AHI1 RBBP5 VPS8 BRWD1

2.35e-03297856IPR017986
DomainSIAH-type

TRAF4 TRAF6

2.36e-0316852IPR013323
DomainPkinase_Tyr

LIMK1 FGFR1 FGFR3 FGFR2

2.86e-03129854PF07714
Domain-

TRIM46 FLNC SEMA3C SDK2 CADM1 FGFR1 FGFR3 FGFR2 EPB42

3.16e-036638592.60.40.10
DomainCH

FLNC VAV3 UTRN

3.24e-0365853SM00033
DomainSer-Thr/Tyr_kinase_cat_dom

LIMK1 FGFR1 FGFR3 FGFR2

3.64e-03138854IPR001245
DomainPH

RASGRF1 NGEF CNKSR2 VAV3 PREX1

3.93e-03229855PF00169
DomainCH

FLNC VAV3 UTRN

4.00e-0370853PF00307
Domain-

FLNC VAV3 UTRN

4.16e-03718531.10.418.10
DomainIGc2

SDK2 CADM1 FGFR1 FGFR3 FGFR2

4.38e-03235855SM00408
DomainIg_sub2

SDK2 CADM1 FGFR1 FGFR3 FGFR2

4.38e-03235855IPR003598
DomainDAPIN

NLRP9 NLRP5

4.46e-0322852PS50824
DomainPYRIN

NLRP9 NLRP5

4.46e-0322852PF02758
DomainDAPIN

NLRP9 NLRP5

4.46e-0322852IPR004020
DomainPYRIN

NLRP9 NLRP5

4.46e-0322852SM01289
DomainCH

FLNC VAV3 UTRN

4.50e-0373853PS50021
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL

FGFR1 FGFR3 FGFR2 CBL

5.80e-0625684M47934
PathwayPID_FGF_PATHWAY

HGF FGFR1 FGFR3 FGFR2 CBL

6.49e-0655685M276
PathwayPID_RAC1_REG_PATHWAY

RASGRF1 NGEF VAV3 PREX1

3.23e-0538684M241
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

HGF FGFR1 FGFR3 FGFR2

1.40e-0455684M47952
PathwayWP_MAPK_SIGNALING

FLNC TRAF6 RASGRF1 FGFR1 FGFR3 FGFR2 HSPA1L

1.77e-04246687M39597
PathwayWP_BURN_WOUND_HEALING

HGF TLR1 FGFR1 FGFR3 FGFR2

2.11e-04113685M42571
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

HGF TRAF6 FGFR1 FGFR3 FGFR2

2.58e-04118685M713
PathwayKEGG_MAPK_SIGNALING_PATHWAY

FLNC TRAF6 RASGRF1 FGFR1 FGFR3 FGFR2 HSPA1L

2.92e-04267687M10792
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

TRAF6 NGEF VAV3 PREX1

3.57e-0470684MM14824
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_PI3K_SIGNALING_PATHWAY

FGFR1 FGFR3 FGFR2

4.38e-0431683M47396
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

TRAF6 NGEF VAV3 PREX1

4.89e-0476684M19832
PathwayPID_EPHA_FWDPATHWAY

NGEF VAV3 CBL

5.77e-0434683M177
PathwayKEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY

FGFR1 FGFR3 FGFR2

6.29e-0435683M47379
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

HGF FGFR1 FGFR3 FGFR2

6.83e-0483684M27163
PathwayWP_GLIOBLASTOMA_SIGNALING

PIK3C2A FGFR1 FGFR2 CBL

6.83e-0483684M39637
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY

HGF FGFR1 FGFR3 FGFR2

6.83e-0483684M47961
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

TRAF6 NGEF VAV3 PREX1

7.47e-0485684MM14746
PathwayREACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

HGF TRAF6 SCMH1 FGFR1 FGFR3 FGFR2 TRIM27

7.56e-04313687M27867
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

LIMK1 PIK3C2A FGFR1 FGFR3 FGFR2

7.76e-04150685M39520
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY

FGFR1 FGFR2

8.08e-049682M47397
PathwayWP_REGULATION_OF_ACTIN_CYTOSKELETON

LIMK1 PIK3C2A FGFR1 FGFR3 FGFR2

8.24e-04152685MM15834
PathwayREACTOME_SIGNALING_BY_FGFR

FGFR1 FGFR3 FGFR2 CBL

8.88e-0489684M1090
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY

HGF FGFR1 FGFR3 FGFR2

8.88e-0489684M47963
PathwayKEGG_PATHWAYS_IN_CANCER

HGF TRAF4 TRAF6 FGFR1 FGFR3 FGFR2 CBL

9.43e-04325687M12868
PathwayKEGG_MEDICUS_REFERENCE_GF_RTK_RAS_ERK_SIGNALING_PATHWAY

HGF FGFR1 FGFR3 FGFR2

1.01e-0392684M47927
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

TRAF6 NGEF VAV3 PREX1

1.22e-0397684M9400
Pubmed

Transient Redirection of SVZ Stem Cells to Oligodendrogenesis by FGFR3 Activation Promotes Remyelination.

FGFR1 FGFR3 FGFR2

1.79e-08392331189094
Pubmed

Isolation of the complementary DNA encoding a mouse heparin-binding growth factor receptor with the use of a unique kinase insert sequence.

FGFR1 FGFR3 FGFR2

1.79e-0839238382556
Pubmed

Fibroblast growth factor receptor signaling in pediatric B-cell precursor acute lymphoblastic leukemia.

FGFR1 FGFR3 FGFR2

1.79e-08392330755670
Pubmed

Differential roles of fibroblast growth factor receptors (FGFR) 1, 2 and 3 in the regulation of S115 breast cancer cell growth.

FGFR1 FGFR3 FGFR2

1.79e-08392323185502
Pubmed

Fibroblast growth factor receptors in in vitro and in vivo chondrogenesis: relating tissue engineering using adult mesenchymal stem cells to embryonic development.

FGFR1 FGFR3 FGFR2

1.79e-08392319728793
Pubmed

FGFR Craniosynostosis Syndromes Overview

FGFR1 FGFR3 FGFR2

1.79e-08392320301628
Pubmed

Expression of fibroblast growth factor receptor1, -2c, and -3c transcripts in mouse molars after tooth eruption.

FGFR1 FGFR3 FGFR2

1.79e-08392333433858
Pubmed

Expression of fibroblast growth factor receptors (FGFR1, FGFR2, FGFR3) in the developing head and face.

FGFR1 FGFR3 FGFR2

1.79e-0839239286594
Pubmed

Fibroblast growth factor (FGF) 3 from Xenopus laevis (XFGF3) binds with high affinity to FGF receptor 2.

FGFR1 FGFR3 FGFR2

1.79e-0839237896824
Pubmed

FGF-FGFR Mediates the Activity-Dependent Dendritogenesis of Layer IV Neurons during Barrel Formation.

FGFR1 FGFR3 FGFR2

1.79e-08392329097598
Pubmed

Enriched Environment Promotes Adult Hippocampal Neurogenesis through FGFRs.

FGFR1 FGFR3 FGFR2

1.79e-08392333637561
Pubmed

Fibroblast growth factor receptor (FGFR) gene amplifications are rare events in bladder cancer.

FGFR1 FGFR3 FGFR2

1.79e-08392324898159
Pubmed

FGFR mutations and plagiocephaly.

FGFR1 FGFR3 FGFR2

1.79e-08392318216705
Pubmed

Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes.

FGFR1 FGFR3 FGFR2

1.79e-08392331830366
Pubmed

FGFR1/3 tyrosine kinase fusions define a unique molecular subtype of non-small cell lung cancer.

FGFR1 FGFR3 FGFR2

1.79e-08392324850843
Pubmed

Somatic FGFR and TWIST mutations are not a common cause of isolated nonsyndromic single suture craniosynostosis.

FGFR1 FGFR3 FGFR2

7.15e-08492317414280
Pubmed

Isolated sagittal and coronal craniosynostosis associated with TWIST box mutations.

FGFR1 FGFR3 FGFR2

7.15e-08492317343269
Pubmed

Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis.

FGFR1 FGFR3 FGFR2

7.15e-08492310704861
Pubmed

Differential expression of the fibroblast growth factor receptor (FGFR) multigene family in normal human adult tissues.

FGFR1 FGFR3 FGFR2

7.15e-0849239212826
Pubmed

Astrocyte activation is suppressed in both normal and injured brain by FGF signaling.

FGFR1 FGFR3 FGFR2

7.15e-08492325002516
Pubmed

FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer.

FGFR1 FGFR3 FGFR2

7.15e-08492336142417
Pubmed

Immunohistochemical detection of fibroblast growth factor receptors in normal endocrine cells and related tumors of the digestive system.

FGFR1 FGFR3 FGFR2

7.15e-08492311759058
Pubmed

Lens fiber cell differentiation occurs independently of fibroblast growth factor receptor signaling in the absence of Pten.

FGFR1 FGFR3 FGFR2

7.15e-08492332858001
Pubmed

Differential expression of fibroblast growth factor receptors in the developing murine choroid plexus.

FGFR1 FGFR3 FGFR2

7.15e-08492312644244
Pubmed

Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9.

FGFR1 FGFR3 FGFR2

7.15e-0849239664689
Pubmed

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.

FGFR1 FGFR3 FGFR2

7.15e-08492327154171
Pubmed

Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin.

FGFR1 FGFR3 FGFR2

7.15e-08492312373339
Pubmed

The FGF system has a key role in regulating vascular integrity.

FGFR1 FGFR3 FGFR2

7.15e-08492318776942
Pubmed

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector.

FGFR1 FGFR3 FGFR2

7.15e-08492317304337
Pubmed

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.

FGFR1 FGFR3 FGFR2

1.78e-07592315987787
Pubmed

The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes.

FGFR1 FGFR3 FGFR2

1.78e-07592327078042
Pubmed

Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors.

FGFR1 FGFR3 FGFR2

1.78e-07592316091423
Pubmed

FGF-dependent regulation of VEGF receptor 2 expression in mice.

FGFR1 FGFR3 FGFR2

1.78e-07592321633168
Pubmed

FGF21 signalling pathway and metabolic traits - genetic association analysis.

FGFR1 FGFR3 FGFR2

1.78e-07592320717167
Pubmed

Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1.

FGFR1 FGFR3 FGFR2

1.78e-07592319696444
Pubmed

Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands.

FGFR1 FGFR3 FGFR2

1.78e-07592327206683
Pubmed

Expression of fibroblast growth factor receptors in peri-implantation mouse embryos.

FGFR1 FGFR3 FGFR2

1.78e-0759239771645
Pubmed

Nectin-1 binds and signals through the fibroblast growth factor receptor.

FGFR1 FGFR3 FGFR2

1.78e-07592322955284
Pubmed

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

FGFR1 FGFR3 FGFR2

1.78e-07592328094278
Pubmed

Expression and biological activity of mouse fibroblast growth factor-9.

FGFR1 FGFR3 FGFR2

1.78e-0759238576175
Pubmed

Craniosynostosis: genes and mechanisms.

FGFR1 FGFR3 FGFR2

1.78e-0759239300656
Pubmed

Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands.

FGFR1 FGFR3 FGFR2

1.78e-0759239013630
Pubmed

The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.

FGFR1 FGFR3 FGFR2

1.78e-07592311566361
Pubmed

Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.

FGFR1 FGFR3 FGFR2

3.56e-07692310572038
Pubmed

The complex morphology of reactive astrocytes controlled by fibroblast growth factor signaling.

FGFR1 FGFR3 FGFR2

3.56e-07692324796693
Pubmed

Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1.

FGFR1 FGFR3 FGFR2

3.56e-07692324026051
Pubmed

FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells.

FGFR1 FGFR3 FGFR2

3.56e-0769239010207
Pubmed

Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains.

FGFR1 FGFR3 FGFR2

3.56e-07692316365308
Pubmed

Regulation of fibroblast growth factor-23 signaling by klotho.

FGFR1 FGFR3 FGFR2

3.56e-07692316436388
Pubmed

Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.

FGFR1 FGFR3 FGFR2

3.56e-07692319232523
Pubmed

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.

FGFR1 FGFR3 FGFR2

3.56e-07692329720668
Pubmed

Gyrification of the cerebral cortex requires FGF signaling in the mammalian brain.

FGFR1 FGFR3 FGFR2

3.56e-07692329132503
Pubmed

Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb.

FGFR1 FGFR3 FGFR2

3.56e-07692338056728
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

TRIM46 TRAF4 TRAF6 MKRN2 TRIM27 CBL

3.79e-0710592622493164
Pubmed

Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme.

HGF FGFR1 FGFR3 FGFR2

3.91e-072392420934536
Pubmed

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

TRAF6 RASGRF1 NGEF VAV3 PREX1

5.65e-076092512787561
Pubmed

Expression patterns of FGF receptors in the developing mammalian cochlea.

FGFR1 FGFR3 FGFR2

6.22e-07792320131355
Pubmed

FGF as a target-derived chemoattractant for developing motor axons genetically programmed by the LIM code.

FGFR1 FGFR3 FGFR2

6.22e-07792316772167
Pubmed

Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells.

FGFR1 FGFR3 FGFR2

6.22e-0779238959336
Pubmed

Fibroblast Growth Factor 2 Modulates Hypothalamic Pituitary Axis Activity and Anxiety Behavior Through Glucocorticoid Receptors.

FGFR1 FGFR3 FGFR2

6.22e-07792327133954
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

TRAF4 MYO5A RBBP5 PA2G4 MAZ NGEF CNKSR2 VAV3 TOMM40 ARHGAP18 TRIM27 UTRN PREX1

8.84e-07916921332203420
Pubmed

Expression of FGF receptors 1, 2, 3 in the embryonic and postnatal mouse brain compared with Pdgfralpha, Olig2 and Plp/dm20: implications for oligodendrocyte development.

FGFR1 FGFR3 FGFR2

9.94e-07892312966207
Pubmed

FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors.

FGFR1 FGFR3 FGFR2

9.94e-07892314602678
Pubmed

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.

FGFR1 FGFR3 FGFR2

9.94e-07892318187602
Pubmed

Molecular mechanisms in calvarial bone and suture development, and their relation to craniosynostosis.

FGFR1 FGFR3 FGFR2

9.94e-07892312737212
Pubmed

Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula.

FGFR1 FGFR3 FGFR2

9.94e-07892328389228
Pubmed

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

FGFR1 FGFR3 FGFR2

9.94e-07892317623664
Pubmed

Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones.

FGFR1 FGFR3 FGFR2

9.94e-07892319218784
Pubmed

Syndecan-4 dependent FGF stimulation of mouse vibrissae growth.

FGFR1 FGFR3 FGFR2

9.94e-07892316989989
Pubmed

Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.

SEMA3C FGFR1 FGFR3 FGFR2

1.37e-063192422076636
Pubmed

Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse.

FGFR1 FGFR3 FGFR2

1.49e-06992315830353
Pubmed

Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development.

FGFR1 FGFR3 FGFR2

1.49e-06992331613912
Pubmed

Integration of FGF and TWIST in calvarial bone and suture development.

FGFR1 FGFR3 FGFR2

1.49e-06992310751173
Pubmed

FGF Signaling Directs the Cell Fate Switch from Neurons to Astrocytes in the Developing Mouse Cerebral Cortex.

FGFR1 FGFR3 FGFR2

1.49e-06992331175212
Pubmed

The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear.

FGFR1 FGFR3 FGFR2

1.49e-06992311335076
Pubmed

Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination.

FGFR1 FGFR3 FGFR2

1.49e-06992315229180
Pubmed

FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion.

FGFR1 FGFR3 FGFR2

2.12e-061092319219044
Pubmed

Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling.

FGFR1 FGFR3 FGFR2

2.12e-061092315470137
Pubmed

Regulation of external genitalia development by concerted actions of FGF ligands and FGF receptors.

FGFR1 FGFR3 FGFR2

2.12e-061092315340846
Pubmed

Fgf20 is required for sensory epithelial specification in the developing cochlea.

FGFR1 FGFR3 FGFR2

2.91e-061192318524904
Pubmed

Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain.

FGFR1 FGFR3 FGFR2

2.91e-061192321451043
Pubmed

FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching.

FGFR1 FGFR3 FGFR2

2.91e-061192332127497
Pubmed

Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle.

FGFR1 FGFR3 FGFR2

2.91e-06119238901049
Pubmed

Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.

FGFR1 FGFR3 FGFR2

2.91e-061192326906157
Pubmed

The murine gene, Traube, is essential for the growth of preimplantation embryos.

FGFR1 FGFR3 FGFR2

2.91e-061192311071758
Pubmed

Loss of Dlg-1 in the mouse lens impairs fibroblast growth factor receptor signaling.

FGFR1 FGFR3 FGFR2

2.91e-061192324824078
Pubmed

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.

FGFR1 FGFR3 FGFR2

2.91e-061192311937494
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

RASGRF1 NGEF VAV3 PREX1

3.16e-063892411756498
Pubmed

Fibroblast-growth-factor receptor mutations in human skeletal disorders.

FGFR1 FGFR3 FGFR2

3.87e-06129238585128
Pubmed

Immunohistochemical study of genesis of the mouse oral vestibule.

FGFR1 FGFR3 FGFR2

3.87e-061292314964469
Pubmed

Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures.

FGFR1 FGFR3 FGFR2

3.87e-061292310751172
Pubmed

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.

FGFR1 FGFR3 FGFR2

3.87e-061292312460940
Pubmed

The roles of FGF signaling in germ cell migration in the mouse.

FGFR1 FGFR3 FGFR2

3.87e-061292316291796
Pubmed

Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.

FGFR1 FGFR3 FGFR2

5.03e-061392328938467
Pubmed

A quantitative method for evaluation of FGF family and FGF receptor family gene expression by RT-PCR.

FGFR1 FGFR3 FGFR2

5.03e-06139239385055
Pubmed

Apoptosis, proliferation and gene expression patterns in mouse developing tongue.

FGFR1 FGFR3 FGFR2

5.03e-061392316151852
Pubmed

A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome.

FGFR1 FGFR3 FGFR2

5.03e-061392328169396
Pubmed

Expression of the fibroblast growth factor family and their receptor family genes during mouse brain development.

FGFR1 FGFR3 FGFR2

5.03e-06139238883961
Pubmed

Receptor specificity of the fibroblast growth factor family.

FGFR1 FGFR3 FGFR2

5.03e-06139238663044
Pubmed

Early thyroid development requires a Tbx1-Fgf8 pathway.

FGFR1 FGFR3 FGFR2

5.03e-061392319389367
InteractionNECTIN1 interactions

FGFR1 FGFR3 FGFR2 CBL

2.56e-0622904int:NECTIN1
InteractionFGF6 interactions

FGFR1 FGFR3 FGFR2

2.98e-067903int:FGF6
InteractionFGF18 interactions

FGFR1 FGFR3 FGFR2

2.98e-067903int:FGF18
InteractionFGF5 interactions

FGFR1 FGFR3 FGFR2

4.75e-068903int:FGF5
InteractionFGF23 interactions

FGFR1 FGFR3 FGFR2

4.75e-068903int:FGF23
InteractionKLB interactions

FGFR1 FGFR3 FGFR2

1.84e-0512903int:KLB
InteractionKL interactions

FGFR1 FGFR3 FGFR2

3.03e-0514903int:KL
InteractionFGF7 interactions

FGFR1 FGFR3 FGFR2

4.62e-0516903int:FGF7
InteractionFGF9 interactions

FGFR1 FGFR3 FGFR2

4.62e-0516903int:FGF9
InteractionFBXW10B interactions

FBXW10B FBXW10

5.90e-053902int:FBXW10B
InteractionERBB2 interactions

ZFAND1 HGF TRAF4 PIK3C2A SUPT6H MKRN2 VAV3 FGFR1 FGFR3 FGFR2 CBL

6.23e-055899011int:ERBB2
InteractionFBLIM1 interactions

KIF18A FLNC CBL FAN1

7.92e-0551904int:FBLIM1
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF1 NGEF VAV3 PREX1

1.11e-0466684722
GeneFamilyTNF receptor associated factors

TRAF4 TRAF6

2.89e-0476821056
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SEMA3C SDK2 FGFR1 FGFR3 FGFR2

3.49e-04161685593
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FGFR1 FGFR3 FGFR2

4.55e-0440683321
GeneFamilyRing finger proteins

TRIM46 TRAF4 TRAF6 MKRN2 TRIM27 CBL

5.83e-0427568658
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

7.50e-0411682559
GeneFamilyWD repeat domain containing

FBXW10B FBXW10 AHI1 RBBP5 BRWD1

3.05e-03262685362
GeneFamilyNLR family

NLRP9 NLRP5

3.95e-0325682666
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP9 NLRP5

3.95e-0325682994
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF1 CNKSR2 VAV3 PREX1

7.55e-03206684682
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRIM46 ABCA3 SDK2 CADM1 FGFR2 UTRN

2.29e-061869164e94158db52df41d71e67b02b9895a358eebee0f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SNX30 CPAMD8 CADM1 RASGRF1 FGFR3 FGFR2

2.67e-0619191634cc997e4e5c727495f321e6807a84aa124da486
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CADM1 MYO5A FGFR2 ZDHHC1 UTRN E2F8

3.29e-0619891684697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CADM1 MYO5A FGFR2 ZDHHC1 UTRN E2F8

3.29e-06198916eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TRIM46 FLNC ABCA3 ZNF728 HFM1 HPSE2

3.29e-061989161e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PIK3C2A ASH1L ARHGAP18 UTRN BRWD1 NIN

3.48e-06200916dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SNX30 FAT2 ABCA3 CADM1 RASGRF1

2.19e-05164915beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

SNX30 FAT2 ABCA3 CADM1 RASGRF1

2.19e-05164915d005cfd821b87548b075120bffe65a0be9860463
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

3.79e-051849150ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

HGF MYO5A ZNF728 MED13L UTRN

3.79e-0518491567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

3.79e-051849152a8338e94937686a148b5433515700ca0f674058
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.09e-051879155df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA3 SDK2 CADM1 FGFR2 UTRN

4.09e-0518791558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

SEMA3C SDK2 CARMIL1 PPM1E ARHGAP18

4.09e-05187915ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.31e-05189915dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

FLNC SEMA3C AEBP1 HPSE2 FGFR1

4.41e-05190915645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 USP53 CPSF4L FGFR2 ARMCX4

4.41e-05190915c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 USP53 CPSF4L FGFR2 ARMCX4

4.41e-05190915d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.53e-05191915a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.53e-05191915276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SNX30 ABCA3 CADM1 RASGRF1 AEBP1

4.53e-05191915f00d6824bd138b192a996e9f7de57b235bb24c18
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.64e-0519291558c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.64e-05192915fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

USP53 SEMA3C SDK2 CADM1 PREX1

4.76e-051939153ea6b103e35bbb276e95301999618558fa3e38b1
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.76e-05193915fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnormal_Lung-Epithelial_cells-AT2|normal_Lung / Location, Cell class and cell subclass

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.76e-0519391580ad1bdc50ecb8a50362f718248441cae20904a6
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.76e-05193915738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

4.76e-05193915f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

AHI1 CADM1 MAZ UTRN E2F8

4.87e-05194915dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCelldistal-Epithelial-Differentiating_Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IVL TRAF4 FAT2 FGFR3 FGFR2

4.99e-051959153fe6e49a9161fc9e5160251e6932cb5378175a54
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 HGF SEMA3C AEBP1 FGFR1

4.99e-05195915f54bc4454270ff06e85596f98199372b50d0179f
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC SEMA3C AEBP1 FGFR1 FGFR2

5.12e-051969152029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCelldistal-3-Epithelial-Differentiating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IVL TRAF4 FAT2 PPM1E FGFR3

5.12e-0519691577635a0f86910c4019d3370e9c8ba41de176bcf3
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 CADM1 CARMIL1 FGFR3 FGFR2

5.24e-051979156e111ba16fc8adde782b3f7da250248cddf11228
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 CADM1 CARMIL1 FGFR3 FGFR2

5.24e-051979154b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO5A VAV3 ARHGAP18 CBL PREX1

5.24e-05197915f18807124b91310fcd84238484a80ecdba684679
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 CADM1 CARMIL1 FGFR3 FGFR2

5.24e-05197915ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF SEMA3C AEBP1 FGFR1 UTRN

5.24e-051979159b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

USP53 SDK2 AEBP1 FGFR1 FGFR3

5.24e-05197915a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SNX30 ABCA3 CADM1 RASGRF1 UTRN

5.37e-0519891585215015bb86ada0e871c413a4ecdc903a3785ca
ToppCellImmune|World / Lineage, Cell type, age group and donor

MYO5A VAV3 ARHGAP18 CBL PREX1

5.37e-0519891565681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.37e-05198915f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.37e-051989152e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell18-Distal-Epithelial-Bud_tip_progenitor|Distal / Age, Tissue, Lineage and Cell class

CADM1 RASGRF1 MYO5A FGFR2 E2F8

5.37e-05198915fdd3b428483dbca0fc5b1412446a812e8ad616a9
ToppCellfacs-Trachea-nan-3m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 CADM1 CARMIL1 FGFR3 FGFR2

5.37e-0519891571e847e8c24744d6df4a960348ad2ecf310373b4
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SNX30 ABCA3 CADM1 RASGRF1 UTRN

5.37e-0519891538349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCelldistal-3-Epithelial-Signaling_Alveolar_Epithelial_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-05200915a77087a393aad674d4aa457ca6c0077b0424053d
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-052009153c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCelldistal-Epithelial-Signaling_Alveolar_Epithelial_Type_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-05200915f47bb79202a59404e4916993a1f59cffcf710320
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-05200915c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO5A TLR1 VAV3 ARHGAP18 PREX1

5.63e-05200915ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

USP53 HGF SDK2 AEBP1 CNKSR2

5.63e-05200915aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-0520091523088edc62bf7d4db890937bfd7925dc316fcc76
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

USP53 HGF SDK2 AEBP1 CNKSR2

5.63e-05200915a510deaada669e690329183e18df02870bd204b3
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-05200915acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-05200915ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCelldistal-Epithelial-Signaling_Alveolar_Epithelial_Type_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-05200915b0e5c8b425f47833cdc00b5aa3734c8c980f0967
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-0520091535c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SNX30 ABCA3 CADM1 RASGRF1 FGFR2

5.63e-05200915eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP53 HGF SDK2 AEBP1 CNKSR2

5.63e-05200915dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA3 CADM1 FGFR2 UTRN

1.46e-041309146434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3C UBTFL1 FGFR2 SYCE2

1.51e-041319149ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C NLRP9 APOBEC2 PPM1E

2.47e-0414991461d84838a841ed2d6b8c5f86d423a4e6b3dcc9cb
ToppCellCOVID-19-Myeloid-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

TLR1 VAV3 ARHGAP18 PREX1

2.94e-04156914a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZFAND1 SDK2 DUS4L HSPA1L

3.09e-041589146d2709b387945c015faa223c20d22b52a4082140
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2|TCGA-Lung / Sample_Type by Project: Shred V9

UBTFL1 PPM1E E2F8 SYCE2

3.09e-041589149dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCell18-Airway-Epithelial-Bud_tip_progenitor|Airway / Age, Tissue, Lineage and Cell class

USP53 RASGRF1 MYO5A E2F8

3.16e-04159914e715cadff8e7d5ebe4c2198dbdfd3ca41ecb8a6a
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

SNX30 ABCA3 CADM1 RASGRF1

3.24e-04160914ac5d573c135d66d6adddd42dfddd9d3e01532172
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SNX30 ABCA3 CADM1 RASGRF1

3.24e-04160914b81d218c20fe37921cf3c6c7db2da3bfd367230a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 SEMA3C DHRS7 ARHGAP18

3.64e-04165914a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Liver / Manually curated celltypes from each tissue

AHI1 CARMIL1 CNKSR2 ARMCX4

3.72e-041669149afa33b5ad27dc33576be592f9b22d8161366838
ToppCellfacs-Marrow-T_cells-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM1 DHRS7 HPSE2 NIN

3.72e-04166914fab4da2537904ad114218f720e18a600f14a00a1
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPM1E E2F8 SYCE2 NLRP5

3.81e-04167914bad33497ceeab968a7eb8a48b921c6f936390743
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Lung / Manually curated celltypes from each tissue

KIF18A ZNF567 SCMH1 PREX1

3.81e-04167914dcbcc658082910838c8082d71a64917055086cc4
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SDK2 MYO5A TLR1 SYCE2

3.89e-04168914cc0dd43d5cda01e643d8e8d74ec7617d61890760
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LIMK1 FAT2 TLR1 PPM1E

3.89e-041689142dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IVL RASGRF1 FGFR2 SYCE2

3.89e-0416891408f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ANKRD35 HARS2 TRAF6 HSPA1L

3.98e-0416991429db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ANKRD35 HARS2 TRAF6 HSPA1L

3.98e-04169914b1611e61f635f8f9b87250e026ad30999cbee041
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

FLNC MYO5A VAV3 ARHGAP18

4.07e-041709144232fe937909f93d3736988c707b8f95ce993398
ToppCelldroplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 RASGRF1 CARMIL1 PPM1E

4.07e-04170914749144a1a869a6bf9acdd227184319083367dc3f
ToppCell3'_v3-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

TRIM46 TRPM6 CNKSR2 MED13L

4.07e-041709144dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCelldroplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 RASGRF1 CARMIL1 PPM1E

4.07e-0417091425d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C NGEF FGFR3 FGFR2

4.16e-041719145447b78148f7bccb727e2fc108589b2af02a5d31
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

TRPM6 FAT2 FGFR3 FGFR2

4.16e-041719143965ced4be6db14265a90673502fceee425837ca
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SNX30 SDK2 CADM1 VAV3

4.16e-0417191404346d4eb726875e3537e215ea081a0318ca4ddd
ToppCelldroplet-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C AEBP1 FGFR3 FGFR2

4.16e-0417191492ac4cc3d54da2ea8e202aa59c78e8875356649e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRAF4 RASGRF1 CARMIL1 PPM1E

4.25e-04172914422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 AHI1 ADAMTS20 NLRP5

4.25e-04172914b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C NGEF FGFR3 FGFR2

4.25e-04172914a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RBBP5 ASH1L ARMCX4 MED13L

4.25e-04172914da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C NGEF FGFR3 FGFR2

4.25e-041729140a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRAF4 RASGRF1 CARMIL1 PPM1E

4.25e-041729141abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

USP53 MAZ NPDC1 BRWD1

4.25e-041729148a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC AEBP1 HPSE2 UTRN

4.35e-04173914fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC AEBP1 HPSE2 UTRN

4.35e-04173914901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEMA3C SDK2 FGFR1 UTRN

4.44e-04174914912a9e892b29d945666fc37c986009c97c668ac8
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

CADM1 PPM1E FGFR3 FGFR2

4.44e-04174914430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF FBXW10B SEMA3C FGFR1

4.54e-04175914910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

IVL SNX30 FAT2 FGFR3

4.54e-041759140cc215109d9915af47e4d0a120ce2e46910715fa
Drug3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea

FGFR1 FGFR3 FGFR2

2.15e-074873ctd:C568950
DrugPalifermin

FGFR1 FGFR3 FGFR2

1.07e-066873DB00039
DrugHeparitin Sulfate

HGF FGFR1 FGFR3 FGFR2

4.39e-0629874ctd:D006497
Drug15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A

TRAF4 AHI1 MAZ FGFR1 FGFR3 FGFR2 E2F8

9.94e-061958775228_DN
DrugPD 166285

FGFR1 FGFR3 FGFR2

1.16e-0512873CID005311382
DrugSU4984

FGFR1 FGFR2

1.44e-052872DB02058
DrugPD 173074

HGF FGFR1 FGFR3

1.90e-0514873ctd:C115711
Drug5H-benzo(4,5)cyclohepta(1,2-b)pyridin-5-one

FGFR1 FGFR3 FGFR2

2.91e-0516873ctd:C561052
DiseaseTWIST1-related craniosynostosis

FGFR1 FGFR3 FGFR2

1.02e-074883cv:C4551902
Diseasebone disease (implicated_via_orthology)

FGFR1 FGFR3 FGFR2

2.55e-075883DOID:0080001 (implicated_via_orthology)
DiseaseCraniosynostosis syndrome

FGFR1 FGFR3 FGFR2

8.89e-077883cv:C0010278
DiseaseJACKSON-WEISS SYNDROME

FGFR1 FGFR2

8.79e-062882C0795998
DiseaseFGFR2-related craniosynostosis

FGFR1 FGFR2

8.79e-062882cv:CN231480
DiseasePFEIFFER SYNDROME

FGFR1 FGFR2

8.79e-062882101600
DiseaseCutis Gyrata Syndrome of Beare And Stevenson

FGFR1 FGFR2

8.79e-062882C1852406
DiseasePfeiffer type acrocephalosyndactyly

FGFR1 FGFR2

8.79e-062882C2931888
DiseaseIsolated coronal synostosis

FGFR3 FGFR2

8.79e-062882cv:CN043619
DiseaseJackson-Weiss syndrome

FGFR1 FGFR2

8.79e-062882cv:C0795998
DiseaseJackson-Weiss syndrome (is_implicated_in)

FGFR1 FGFR2

8.79e-062882DOID:0111337 (is_implicated_in)
DiseasePfeiffer syndrome

FGFR1 FGFR2

8.79e-062882cv:C0220658
DiseaseJACKSON-WEISS SYNDROME

FGFR1 FGFR2

8.79e-062882123150
DiseasePfeiffer syndrome (is_implicated_in)

FGFR1 FGFR2

8.79e-062882DOID:14705 (is_implicated_in)
DiseasePfeiffer syndrome (implicated_via_orthology)

FGFR1 FGFR2

8.79e-062882DOID:14705 (implicated_via_orthology)
DiseaseBrachycephaly

FGFR1 FGFR3 FGFR2

1.69e-0517883C0221356
DiseaseLacrimoauriculodentodigital syndrome

FGFR3 FGFR2

2.63e-053882C0265269
DiseaseCraniofacial dysostosis type 1

FGFR1 FGFR2

2.63e-053882C2931196
DiseaseLevy-Hollister syndrome

FGFR3 FGFR2

2.63e-053882cv:C0265269
Diseaseacrocephalosyndactylia (is_implicated_in)

FGFR1 FGFR2

2.63e-053882DOID:12960 (is_implicated_in)
DiseasePfeiffer Syndrome

FGFR1 FGFR2

2.63e-053882C0220658
DiseaseSaethre-Chotzen Syndrome

FGFR3 FGFR2

2.63e-053882C0175699
DiseaseCongenital hypoplasia of radius

FGFR3 FGFR2

2.63e-053882C0685381
DiseaseCleft Palate

FGFR1 FGFR3 FGFR2 MED13L

1.03e-0481884C0008925
Diseasemyeloid neoplasm (is_implicated_in)

FGFR1 CBL

1.83e-047882DOID:0070004 (is_implicated_in)
DiseaseCleft upper lip

FGFR1 FGFR3 FGFR2

2.17e-0439883C0008924
DiseaseCleft palate, isolated

FGFR1 FGFR3 FGFR2

2.70e-0442883C1837218
Diseasehepatocyte growth factor measurement

HGF SEMA3C BRWD1

3.11e-0444883EFO_0006903
Diseasehigh grade glioma (implicated_via_orthology)

FGFR1 FGFR3 FGFR2

3.11e-0444883DOID:3070 (implicated_via_orthology)
DiseaseHead and Neck Carcinoma

FGFR1 FGFR2

3.90e-0410882C3887461
DiseasePolydactyly

AHI1 FGFR1 FGFR3 FGFR2

4.24e-04117884C0152427
Diseasepursuit maintenance gain measurement

SDK2 CARMIL1 NGEF CNKSR2

5.12e-04123884EFO_0008433
Diseasemonoclonal gammopathy

HFM1 CNKSR2 PREX1

5.39e-0453883EFO_0000203
Diseasecraniosynostosis (is_implicated_in)

FGFR3 FGFR2

5.69e-0412882DOID:2340 (is_implicated_in)
Diseasecalcium measurement

TRIM46 TRPM6 HGF OFCC1 HFM1 HPSE2 FGFR1 CBL

5.81e-04628888EFO_0004838
Diseasemiddle temporal gyrus volume measurement, Alzheimer's disease biomarker measurement

CNKSR2 TOMM40

6.71e-0413882EFO_0006514, EFO_0010316
Diseaseatopic eczema

IVL PA2G4 TLR1 FGFR1 PRORP

9.61e-04252885EFO_0000274
Diseasemagnesium measurement

TRIM46 TRPM6 FGFR2

1.02e-0366883EFO_0004845
DiseaseSynostotic Posterior Plagiocephaly

FGFR1 FGFR2

1.03e-0316882C1833340
DiseaseCraniosynostosis, Type 1

FGFR1 FGFR2

1.03e-0316882C4551902
DiseaseAcrocephaly

FGFR1 FGFR2

1.03e-0316882C0030044
Diseasegliosarcoma

FGFR1 FGFR3

1.03e-0316882C0206726
DiseaseTrigonocephaly

FGFR1 FGFR2

1.03e-0316882C0265535
DiseaseScaphycephaly

FGFR1 FGFR2

1.03e-0316882C0265534
DiseaseSynostotic Anterior Plagiocephaly

FGFR1 FGFR2

1.03e-0316882C2931150
DiseaseMetopic synostosis

FGFR1 FGFR2

1.03e-0316882C1860819
Diseasebanks of the superior temporal sulcus volume measurement

NGEF FGFR2

1.16e-0317882EFO_0010286
Diseasejuvenile idiopathic arthritis

AHI1 CARMIL1 VAV3

1.43e-0374883EFO_0002609
DiseaseColorectal Neoplasms

FLNC CPAMD8 ABCA3 PPM1E FGFR3

1.46e-03277885C0009404
DiseaseDisproportionate short stature

FGFR1 FGFR3 FGFR2

1.60e-0377883C0878659
DiseaseCraniosynostosis

FGFR1 FGFR2

1.61e-0320882C0010278
Diseasecomparative body size at age 10, self-reported

CADM1 OFCC1 CNKSR2 FGFR1 MED13L ZDHHC1

1.63e-03420886EFO_0009819
Diseaseosteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty

FGFR3 BRWD1

1.78e-0321882EFO_0004616, EFO_0010726, EFO_1000786
Diseaseliver fibrosis measurement

SCGB1C2 CARMIL1 CBL

2.19e-0386883EFO_0010576
DiseaseCerebral Astrocytoma

HGF FGFR1

2.52e-0325882C0750935
DiseaseIntracranial Astrocytoma

HGF FGFR1

2.52e-0325882C0750936
DiseaseAstrocytoma

HGF FGFR1

2.52e-0325882C0004114
DiseaseGrade I Astrocytoma

HGF FGFR1

2.52e-0325882C1704230
DiseaseSubependymal Giant Cell Astrocytoma

HGF FGFR1

2.52e-0325882C0205768
DiseaseMixed oligoastrocytoma

HGF FGFR1

2.52e-0325882C0547065
DiseasePilocytic Astrocytoma

HGF FGFR1

2.52e-0325882C0334583
DiseaseJuvenile Pilocytic Astrocytoma

HGF FGFR1

2.52e-0325882C0280783
DiseaseDiffuse Astrocytoma

HGF FGFR1

2.52e-0325882C0280785
DiseaseChildhood Cerebral Astrocytoma

HGF FGFR1

2.52e-0325882C0338070
DiseaseFEV change measurement, response to zileuton

SDK2 PRORP

2.52e-0325882EFO_0005921, EFO_0007676
Diseaseunipolar depression, depressive symptom measurement

CNKSR2 PREX1

2.73e-0326882EFO_0003761, EFO_0007006
DiseaseGemistocytic astrocytoma

HGF FGFR1

2.73e-0326882C0334581
DiseaseProtoplasmic astrocytoma

HGF FGFR1

2.73e-0326882C0334580
DiseaseFibrillary Astrocytoma

HGF FGFR1

2.73e-0326882C0334582
Diseasegout

TRIM46 HGF CARMIL1 FGFR2

2.85e-03196884EFO_0004274
DiseaseAnaplastic astrocytoma

HGF FGFR1

2.94e-0327882C0334579
Diseaserefractive error

RASGRF1 OFCC1 CNKSR2 VAV3 ARHGAP18

2.96e-03326885MONDO_0004892

Protein segments in the cluster

PeptideGeneStartEntry
KRQTVEDCPRMGEHQ

PRAMEF33

131

A0A0G2JMD5
CRPHLAIKMPEKAEQ

EPB42

586

P16452
GKMTDEKNEHCPSKR

ASH1L

126

Q9NR48
PFRHDRGEKMVVCKH

CPSF4L

56

A6NMK7
MALQEEKGKPVHCER

AHI1

551

Q8N157
EKVKCPPIGMESHRI

AEBP1

381

Q8IUX7
ERCLMAFKHPKEVLD

FBXW10

606

Q5XX13
LSRQKCPEEVKQMLH

ABCA3

636

Q99758
MEHLIGACRDKEAKI

ANKRD35

916

Q8N283
KCVLPHMIERKQGKI

DHRS7

171

Q9Y394
KDNHCMEVIRLKGLV

CBWD5

306

Q5RIA9
RCKHEANMDPRDLEK

ARMCX4

2031

Q5H9R4
VQHDDNPRCKEMKVT

ADAMTS20

411

P59510
EAGCKLRIMKPQDFE

APOBEC2

171

Q9Y235
PEQRKAHEKICMLTF

MKRN2

206

Q9H000
ERCLMAFKHPKEVLD

FBXW10B

606

O95170
EKKARMGVVECAKHE

PA2G4

286

Q9UQ80
LKEGHRMDKPANCTN

FGFR2

716

P21802
EMCRLGQHKPICKVL

MED13L

1446

Q71F56
GQHKPICKVLRDGIM

MED13L

1451

Q71F56
KMLCEVAIPHNRRKE

KIF18A

746

Q8NI77
DPKAVFQRTKEHCLM

METTL14

276

Q9HCE5
VVPKPKHCQEKMQCE

LLPH

51

Q9BRT6
KDNHCMEVIRLKGLV

CBWD2

306

Q8IUF1
KDNHCMEVIRLKGLV

CBWD1

306

Q9BRT8
RRCKSHKPVAMEDPD

FAT2

4071

Q9NYQ8
QIEKPCKEAMTRHPV

PIK3C2A

536

O00443
KTPCEEVYVKHMGNR

FLNC

2676

Q14315
VRHEEKVPCHVCGKM

MAZ

386

P56270
HKRKELEQMCNPIIT

HSPA1L

596

P34931
EEDVRMACEALKHPK

NLRP5

851

P59047
EHDMTPENFKCKDLR

HGF

336

P14210
QKGCKIAQHPDVMLE

HPSE2

161

Q8WWQ2
HPRDQNKVLVCPMKS

RBBP5

116

Q15291
RRKMEDKHVCIPDFN

PPM1E

241

Q8WY54
PAVCLKMDESHRPVK

HFM1

476

A2PYH4
QQMLCLERHKEPPKE

NPDC1

256

Q9NQX5
ACQTAEKKVIRHDMP

OFCC1

51

Q8IZS5
HEIELRMRKNVKEGC

OPA1

361

O60313
MLKVHKEDDGVPVIC

CADM1

206

Q9BY67
MENEKENLFCEPHKR

E2F8

1

A0AVK6
KLLKEGHRMDKPSNC

FGFR1

711

P11362
RHVTKKMCVAPGEAE

CPAMD8

856

Q8IZJ3
KDNHCMEVIRLKGLV

CBWD3

306

Q5JTY5
KDNHCMEVIRLKGLV

CBWD6

306

Q4V339
DREDGKCHKMEMNPI

BRWD1

1831

Q9NSI6
EKPCKMCEARHKIQA

GET3

286

O43681
AENLCPNVMKKAHIR

CARMIL1

786

Q5VZK9
ENDKDVKIEPCGHLM

CBL

386

P22681
CQERKKDPIEMFHSG

DUS4L

11

O95620
LLKEGHRMDKPANCT

FGFR3

706

P22607
EMEKVVDIPCQAKGV

SDK2

321

Q58EX2
LKEECIPEHMVRGSK

FAN1

221

Q9Y2M0
VDPDVIQTHLDKCMK

UTRN

1466

P46939
GEMGVCEKHREPLKL

TRIM27

91

P14373
RPKGLMCPDHKEEVT

TRIM46

221

Q7Z4K8
RHEMVVKKGLAPEVA

HARS2

251

P49590
IKVEECKMAGKDPTH

SEMA3C

96

Q99985
DELEKMKQLHRCPDL

NIN

1681

Q8N4C6
LKECFRVHKMDDPQR

NGEF

681

Q8N5V2
LKSCRDGLQPMHKAE

SCGB1C2

66

P0DMR2
CDMRIPSDKQDKLHG

PREX1

1206

Q8TCU6
AMDHIEELVSLKPCK

VPS8

961

Q8N3P4
EKHMTAVKGLPEQEC

IVL

61

P07476
MERQGVDVPHVKCKD

SYCE2

1

Q6PIF2
PQDEKMKHCSKIRVI

PRPS1L1

276

P21108
MRDHKACLPDAKTQR

PRORP

501

O15091
KCKVIGFLEEVMHDP

RASGRF1

976

Q13972
MKLEAVDRKNPHFIC

SCMH1

171

Q96GD3
KEGMQICLHERNFVP

TLR1

661

Q15399
KRCNDPVMNEKLHRL

CNKSR2

941

Q8WXI2
HPMCKIEELILGKCD

NLRP9

711

Q7RTR0
ENMGCEKPVIHKSDN

USP53

376

Q70EK8
KRPEERVKVGMTVHC

SUPT6H

1251

Q7KZ85
GCHMTKPDVILKLER

ZNF567

46

Q8N184
HEMIHTGEKPFECKR

ZNF136

466

P52737
VNCHVSMEPEENRKK

UBTFL1

356

P0CB47
KHLADEGMLRPQVKE

TRPM6

331

Q9BX84
PKVPADVEKCQDRME

SNX30

366

Q5VWJ9
HKDELPIEIELGMKC

RMND5B

316

Q96G75
GMHLKCQEEEKPVVI

TRAF6

361

Q9Y4K3
NLMEHKRIHTGEKPC

ZNF728

326

P0DKX0
NIKRNEMVAKHPVTC

ZNF716

76

A6NP11
KQEVHMREKSFPCNE

ZNF808

221

Q8N4W9
LPHRCDETKREMKLG

STAB2

661

Q8WWQ8
CPKLAMARHVEESVK

TRAF4

261

Q9BUZ4
HQKIHMGEKPFECRE

ZNF780B

351

Q9Y6R6
IGDLAPQDMKKVCHL

ARHGAP18

276

Q8N392
CHRKCKELFPIQMEG

TOMM40

86

O96008
KIIPKEEHCKMPEAG

XAGE1A

61

Q9HD64
PHESARLKKACEGMI

TTC37

216

Q6PGP7
HECEKLEIPKPRMAA

ZFAND1

96

Q8TCF1
NHKRAEIQGKMEDLP

WHAMMP3

86

Q1A5X7
AKGVHRELESCPPKM

ZDHHC1

291

Q8WTX9
AMRKACLPGHKQVDR

USP17L10

171

C9JJH3
NIKRNEMVAKHPVTC

ZNF722

76

A0A1W2PQL4
LMKAEEAHQPKCPEN

VAV3

176

Q9UKW4
FLKEVKVMRCLEHPN

LIMK1

381

P53667
CQHGMDPELIKQVVK

MYO5A

1676

Q9Y4I1