Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	CRAL-bd_toc_tran	SEC14L6 SEC14L4 SEC14L2	3.07e-05	12	99	3	IPR001071
Domain	CRAL_TRIO_N	SEC14L6 SEC14L4 SEC14L2	3.07e-05	12	99	3	SM01100
Domain	CRAL/TRIO_N_dom	SEC14L6 SEC14L4 SEC14L2	6.28e-05	15	99	3	IPR011074
Domain	GOLD_dom	SEC14L6 SEC14L4 SEC14L2	1.32e-04	19	99	3	IPR009038
Domain	GOLD	SEC14L6 SEC14L4 SEC14L2	1.32e-04	19	99	3	PS50866
Domain	-	PRPF40A TCERG1	1.66e-04	4	99	2	1.10.10.440
Domain	CRAL_TRIO	SEC14L6 SEC14L4 SEC14L2	1.79e-04	21	99	3	PF00650
Domain	-	SEC14L6 SEC14L4 SEC14L2	2.37e-04	23	99	3	3.40.525.10
Domain	SEC14	SEC14L6 SEC14L4 SEC14L2	3.05e-04	25	99	3	SM00516
Domain	CRAL_TRIO	SEC14L6 SEC14L4 SEC14L2	3.85e-04	27	99	3	PS50191
Domain	FF	PRPF40A TCERG1	4.11e-04	6	99	2	PF01846
Domain	FF	PRPF40A TCERG1	4.11e-04	6	99	2	SM00441
Domain	FF_domain	PRPF40A TCERG1	4.11e-04	6	99	2	IPR002713
Domain	FF	PRPF40A TCERG1	4.11e-04	6	99	2	PS51676
Domain	CRAL-TRIO_dom	SEC14L6 SEC14L4 SEC14L2	4.30e-04	28	99	3	IPR001251
Domain	Hlx-hairpin-Hlx_DNA-bd_motif	ERCC1 POLB	5.74e-04	7	99	2	IPR003583
Domain	HhH1	ERCC1 POLB	5.74e-04	7	99	2	SM00278
Domain	CYSTEINE_SWITCH	ADAMTS19 ADAM17 MMP12	1.33e-03	41	99	3	PS00546
Domain	CRAL_TRIO_N	SEC14L4 SEC14L2	1.48e-03	11	99	2	PF03765
Domain	Pept_M10_metallopeptidase	ADAMTS19 ADAM17 MMP12	1.53e-03	43	99	3	IPR001818
Domain	WW	PRPF40A TCERG1 PLEKHA5	1.98e-03	47	99	3	PF00397
Domain	CYTOCHROME_B5_2	FADS3 NENF	2.09e-03	13	99	2	PS50255
Domain	CYTOCHROME_B5_1	FADS3 NENF	2.09e-03	13	99	2	PS00191
Domain	WW	PRPF40A TCERG1 PLEKHA5	2.10e-03	48	99	3	SM00456
Domain	Cyt-b5	FADS3 NENF	2.43e-03	14	99	2	PF00173
Domain	Cyt_B5-like_heme/steroid-bd	FADS3 NENF	2.43e-03	14	99	2	IPR001199
Domain	Cyt-b5	FADS3 NENF	2.43e-03	14	99	2	SM01117
Domain	-	FADS3 NENF	2.43e-03	14	99	2	3.10.120.10
Domain	WW_DOMAIN_2	PRPF40A TCERG1 PLEKHA5	2.50e-03	51	99	3	PS50020
Domain	WW_DOMAIN_1	PRPF40A TCERG1 PLEKHA5	2.50e-03	51	99	3	PS01159
Domain	WW_dom	PRPF40A TCERG1 PLEKHA5	2.64e-03	52	99	3	IPR001202
Domain	EMP24_GP25L	SEC14L4 SEC14L2	2.79e-03	15	99	2	PF01105
Pubmed	Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis.	SEC14L6 SEC14L4 SEC14L2	9.21e-08	4	100	3	17077281
Pubmed	Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin.	NEB RBM20	8.18e-06	2	100	2	27139341
Pubmed	Oncogenic PIK3CA recruits myeloid-derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5-lipoxygenase-dependent arachidonic acid pathway.	PIK3CA ALOX5	8.18e-06	2	100	2	37965796
Pubmed	PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion.	PTPN22 PTPRC	8.18e-06	2	100	2	32047502
Pubmed	Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice.	RPL22 EDIL3	8.18e-06	2	100	2	36171203
Pubmed	Coordinated processing of 3' slipped (CAG)n/(CTG)n hairpins by DNA polymerases β and δ preferentially induces repeat expansions.	POLB POLD1	8.18e-06	2	100	2	23585564
Pubmed	Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains.	PRPF40A TCERG1	8.18e-06	2	100	2	17915251
Pubmed	PIK3CA mutant tumors depend on oxoglutarate dehydrogenase.	OGDH PIK3CA	8.18e-06	2	100	2	28396387
Pubmed	Regulation of dendritic spines, spatial memory, and embryonic development by the TANC family of PSD-95-interacting proteins.	TANC2 TANC1	8.18e-06	2	100	2	21068316
Pubmed	Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine.	POLB POLD1	8.18e-06	2	100	2	11923315
Pubmed	HIV-host interactome revealed directly from infected cells.	MIA3 HHIP PTPRC ADAM17 TTC13 ABHD16A	1.09e-05	172	100	6	27375898
Pubmed	Tanc1/2 TPR domain interacts with Myo18a C-terminus and undergoes liquid-liquid phase separation.	TANC2 TANC1	2.45e-05	3	100	2	38092135
Pubmed	The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1.	POLB POLD1	2.45e-05	3	100	2	19329428
Pubmed	Rat supernatant protein factor-like protein stimulates squalene monooxygenase and is activated by protein kinase A.	SEC14L4 SEC14L2	2.45e-05	3	100	2	15033454
Pubmed	Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling.	PTPN22 PTPRC	2.45e-05	3	100	2	26077719
Pubmed	alpha-Tocopherol transfer protein inhibition is effective in the prevention of cerebral malaria in mice.	SEC14L6 SEC14L4	2.45e-05	3	100	2	19923370
Pubmed	Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.	EDIL3 PLEKHA5	2.45e-05	3	100	2	28320971
Pubmed	PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background.	PTPN22 PTPRC	2.45e-05	3	100	2	19299707
Pubmed	Male fertility in mice requires classical and nonclassical androgen signaling.	EDIL3 PLEKHA5	2.45e-05	3	100	2	34407397
Pubmed	Deficiency in IL-17-committed Vγ4(+) γδ T cells in a spontaneous Sox13-mutant CD45.1(+) congenic mouse substrain provides protection from dermatitis.	SOX13 PTPRC	2.45e-05	3	100	2	23624556
Pubmed	Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.	NEB RBM20	2.45e-05	3	100	2	27889803
Pubmed	Fgd5 identifies hematopoietic stem cells in the murine bone marrow.	PTPRC FGD5	2.45e-05	3	100	2	24958848
Pubmed	Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach.	RPL22 PLEKHA5	2.45e-05	3	100	2	24606126
Pubmed	Intravital Imaging Reveals Motility of Adult Hematopoietic Stem Cells in the Bone Marrow Niche.	PTPRC FGD5	4.89e-05	4	100	2	32589864
Pubmed	Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.	EDIL3 PIK3CA	4.89e-05	4	100	2	25625625
Pubmed	KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.	KAT2A OGDH	4.89e-05	4	100	2	29211711
Pubmed	CYP26 Enzymes Are Necessary Within the Postnatal Seminiferous Epithelium for Normal Murine Spermatogenesis.	RPL22 PLEKHA5	4.89e-05	4	100	2	26040672
Pubmed	ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway.	PIK3CA ADAM17	4.89e-05	4	100	2	23625205
Pubmed	Molecular cloning and characterization of cDNA for eukaryotic transcription factor S-II.	SEC14L6 SEC14L4	4.89e-05	4	100	2	3346229
Pubmed	Cloning of novel human SEC14p-like proteins: ligand binding and functional properties.	SEC14L4 SEC14L2	4.89e-05	4	100	2	12757856
Pubmed	The Leukotriene B4 and its Receptor BLT1 Act as Critical Drivers of Neutrophil Recruitment in Murine Bullous Pemphigoid-Like Epidermolysis Bullosa Acquisita.	PTPRC ALOX5	4.89e-05	4	100	2	28108297
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	RNASEH2B ADAMTS19 POLB BACH2 TGM6 OGDH FADS3 CARD9 DLG4 HMGXB3 ADAM17 PRMT3 ADGRD1	5.76e-05	1242	100	13	30973865
Pubmed	The lipid-binding SEC14 domain.	SEC14L6 SEC14L2	8.14e-05	5	100	2	17428729
Pubmed	The post-translational modifications of proliferating cell nuclear antigen: acetylation, not phosphorylation, plays an important role in the regulation of its function.	POLB POLD1	8.14e-05	5	100	2	14988403
Pubmed	Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells.	POLB POLD1	8.14e-05	5	100	2	15177179
Pubmed	A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII.	SEC14L6 SEC14L4	8.14e-05	5	100	2	8206389
Pubmed	Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response.	BACH2 PTPRC	8.14e-05	5	100	2	35793628
Pubmed	Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor.	PTPN22 PTPRC	8.14e-05	5	100	2	12612075
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 CCNL2 POLD1 BACH2 KAT2A PRPF40A NUFIP1 XRN1 DLG4 ADAM17 TANC1 C1orf50	8.80e-05	1116	100	12	31753913
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MIA3 SAMD9 RBM20 SLC25A32 TCERG1 XRN1 RNF216 PLEKHA5 TANC1	1.11e-04	650	100	9	38777146
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MIA3 TBC1D31 TCERG1 XRN1 PLEKHA5 TANC1	1.16e-04	263	100	6	34702444
Pubmed	Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study.	ERCC1 POLD1	1.22e-04	6	100	2	28976792
Pubmed	Regulation of prefrontal patterning and connectivity by retinoic acid.	RXRG PLXNC1 DLG4	1.29e-04	34	100	3	34599305
Pubmed	Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells.	ADAMTS19 HHIP HSD3B1	1.54e-04	36	100	3	15944188
Pubmed	Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.	PTPRC PIK3CA	2.27e-04	8	100	2	17846664
Pubmed	Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.	RXRG PLEKHA5	2.27e-04	8	100	2	17124491
Pubmed	Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay.	RPL22 ALOX5	2.91e-04	9	100	2	39096902
Pubmed	Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins.	POLB POLD1	2.91e-04	9	100	2	10559261
Pubmed	Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.	POLB POLD1	2.91e-04	9	100	2	20227374
Pubmed	Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines.	EDIL3 PIK3CA	2.91e-04	9	100	2	39128004
Pubmed	Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair.	POLB POLD1	2.91e-04	9	100	2	16543152
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MIA3 EMC3 DNAJC25 POLD1 OGDH PRPF40A TBC1D31 RPF2 PDIA5 PLEKHA5 TTC13 TANC1 NENF	3.39e-04	1487	100	13	33957083
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 MYOM3 CFAP43 KAT2A ZNF335 USP40 PDIA5 HMGXB3 TANC1 C1orf50 ALOX5	3.40e-04	1105	100	11	35748872
Pubmed	Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway.	ADAMTS19 HHIP HSD3B1	3.41e-04	47	100	3	22496664
Pubmed	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	BACH2 PTPN22 CARD9 IL1RL1	3.60e-04	116	100	4	21102463
Pubmed	Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function.	EDIL3 PTPRC	3.63e-04	10	100	2	18550708
Pubmed	Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.	CDK16 PSKH2	3.63e-04	10	100	2	25495526
Pubmed	The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians.	EDIL3 RBM20	3.63e-04	10	100	2	35476669
Pubmed	Discovery and refinement of loci associated with lipid levels.	UGT1A6 APOH FADS3 DLG4 ALOX5	3.70e-04	211	100	5	24097068
Pubmed	Wt1 dictates the fate of fetal and adult Leydig cells during development in the mouse testis.	PLEKHA5 HSD3B1	4.43e-04	11	100	2	25336526
Pubmed	Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.	IARS1 PTPRC	4.43e-04	11	100	2	24337748
Pubmed	Structural characterization and chromosomal location of the mouse macrophage migration inhibitory factor gene and pseudogenes.	PTPRC MMP12	4.43e-04	11	100	2	7558021
Pubmed	Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.	HHIP MMP12	4.43e-04	11	100	2	24621683
Pubmed	Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development.	ADAMTS19 HHIP HSD3B1	5.14e-04	54	100	3	15533830
Pubmed	IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms.	PTPRC IL1RL1	5.30e-04	12	100	2	26011644
Pubmed	The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1.	PRPF40A TCERG1	5.30e-04	12	100	2	11604498
Pubmed	Genetic variation in the base excision repair pathway and bladder cancer risk.	POLB POLD1	5.30e-04	12	100	2	17203305
Pubmed	Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns.	HHIP MMP12	5.30e-04	12	100	2	25006744
Pubmed	Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.	RXRG PLEKHA5	5.30e-04	12	100	2	26427057
Pubmed	Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity.	IL1RL1 ALOX5	5.30e-04	12	100	2	32160525
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	POLD1 FIGNL2 CFAP43 SPIN4 SLC9C1 RPF2 USP40	5.88e-04	496	100	7	31343991
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	NEB OGDH PRPF40A KIAA1549L ZNF335	5.92e-04	234	100	5	36243803
Pubmed	Comprehensive analysis of DNA repair gene variants and risk of meningioma.	ERCC1 POLB POLD1	6.03e-04	57	100	3	18270339
Pubmed	A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.	DLG4 TANC1	6.25e-04	13	100	2	15673434
Pubmed	Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.	BACH2 PTPN22	6.25e-04	13	100	2	24586183
Pubmed	Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.	UGT1A6 USP40	7.28e-04	14	100	2	21646302
Pubmed	Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.	SLC6A13 FADS3	7.28e-04	14	100	2	23378610
Pubmed	An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy.	PLEKHA5 HSD3B1	7.28e-04	14	100	2	32011766
Pubmed	Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.	HAO1 FGF6	7.28e-04	14	100	2	23263487
Pubmed	Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.	PRPF40A TCERG1	7.28e-04	14	100	2	8605874
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	ERCC1 POLB POLD1 HSD3B1 ALOX5 SEC14L2	7.57e-04	374	100	6	19625176
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	ERCC1 POLB POLD1 HSD3B1 ALOX5 SEC14L2	8.34e-04	381	100	6	18676680
Pubmed	Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.	ERCC1 POLB	8.39e-04	15	100	2	16609022
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	ERCC1 POLB POLD1 HSD3B1 ALOX5 SEC14L2	8.45e-04	382	100	6	19170196
Pubmed	cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels.	PTPRC PIK3CA	9.57e-04	16	100	2	25772358
Pubmed	HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.	PTPRC PIK3CA	9.57e-04	16	100	2	16524887
Pubmed	Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.	ERCC1 POLB POLD1	1.01e-03	68	100	3	20496165
Pubmed	Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.	PTPRC ADAM17	1.08e-03	17	100	2	17804806
Pubmed	Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium.	NEB MMP12	1.08e-03	17	100	2	34622152
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	TANC2 EDIL3 FADS3 PDIA5 PLEKHA5 ADAM17 ABHD16A NENF	1.13e-03	719	100	8	35337019
Pubmed	Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.	RGS9 RXRG	1.22e-03	18	100	2	27405468
Pubmed	A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.	PRPF40A TCERG1 TALDO1	1.34e-03	75	100	3	15383276
Pubmed	TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb.	PLXNC1 DLG4	1.36e-03	19	100	2	37686246
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	ERCC1 POLB POLD1 HSD3B1 ALOX5 SEC14L2	1.39e-03	421	100	6	19692168
Pubmed	Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.	BACH2 PTPN22	1.50e-03	20	100	2	18978792
Pubmed	Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.	ERCC1 POLB	1.50e-03	20	100	2	16195237
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BACH2 SOX13 RBM20 TCERG1 SLF2 ZNF92 TANC1	1.57e-03	588	100	7	38580884
Pubmed	Shared and distinct genetic variants in type 1 diabetes and celiac disease.	BACH2 PTPN22	1.66e-03	21	100	2	19073967
Pubmed	A series of recombinant inbred strains between the BALB/cHeA and STS/A mouse strains.	HAO1 PTPRC	1.66e-03	21	100	2	4042679
Pubmed	Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.	EDIL3 IL1RL1	1.82e-03	22	100	2	24388013
Cytoband	22q12.2	SEC14L6 OSBP2 SEC14L4 SEC14L2	8.21e-06	58	100	4	22q12.2
Cytoband	1q22-q23	ITLN2 RXRG	3.61e-04	13	100	2	1q22-q23
GeneFamily	SEC14 family\|PRELI domain containing	SEC14L6 SEC14L4 SEC14L2	1.20e-06	6	72	3	1063
ToppCell	droplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP6 POLD1 PLXNC1 KCTD14 IL1RL1 SKA3	2.62e-06	173	100	6	2eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UGT1A6 SFMBT2 PTPRC CARD9 PLXNC1 DLG4	3.09e-06	178	100	6	aa9f68a66e292f331faef881bbd0d028f0f2b0c5
Disease	X-21448 measurement	UGT1A6 USP40	4.73e-04	10	97	2	EFO_0800816
Disease	large artery stroke	RGS9 CARD9 FGD5 MMP12	5.37e-04	113	97	4	EFO_0005524
Disease	developmental disorder of mental health (implicated_via_orthology)	TANC2 DLG4 TANC1	5.69e-04	49	97	3	DOID:0060037 (implicated_via_orthology)
Disease	Nasal Cavity Polyp	MIA3 BACH2 IL1RL1	7.98e-04	55	97	3	EFO_1000391
Disease	Myasthenia gravis	PTPN22 SFMBT2	8.15e-04	13	97	2	EFO_0004991
Disease	Genetic chronic primary adrenal insufficiency	BACH2 PTPN22	8.15e-04	13	97	2	Orphanet_101960
Disease	cognitive behavioural therapy	NEB SOX13 TCERG1	9.32e-04	58	97	3	EFO_0007820
Disease	interleukin 18 receptor 1 measurement	APOH IL1RL1	1.09e-03	15	97	2	EFO_0008178
Disease	respiratory system disease	BACH2 PTPRC PLXNC1 IL1RL1	1.36e-03	145	97	4	EFO_0000684
Disease	angiopoietin-related protein 1 measurement	UGT1A6 APOH	1.58e-03	18	97	2	EFO_0801382
Disease	autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease	BACH2 PTPN22	1.58e-03	18	97	2	EFO_0003779, EFO_0004237, EFO_0006812
Disease	childhood trauma measurement, alcohol consumption measurement	TANC2 PCDHGA11 SFMBT2	1.67e-03	71	97	3	EFO_0007878, EFO_0007979
Disease	esophagus adenocarcinoma (is_implicated_in)	ERCC1 MMP12	2.16e-03	21	97	2	DOID:4914 (is_implicated_in)
Disease	Nasopharyngeal carcinoma	ERCC1 PIK3CA	2.37e-03	22	97	2	C2931822
Disease	Carcinoma of lung	ERCC1 PIK3CA	2.59e-03	23	97	2	C0684249
Disease	autoimmune disease	BACH2 PTPN22 PLXNC1 SEC14L2	2.59e-03	173	97	4	EFO_0005140
Disease	Rheumatoid Arthritis	PTPN22 PTPRC MMP12 ALOX5	2.64e-03	174	97	4	C0003873
Disease	Colitis	ADAM17 ALOX5	3.05e-03	25	97	2	C0009319

Protein segments in the cluster

Peptide	Gene	Start	Entry
KAKYPPVNRKYEYLD	ZBTB8OS	21	Q8IWT0
ARSKTYKYSPEKLIY	FAM228A	126	Q86W67
LYKKYLKEPKASYSS	ERICH6B	206	Q5W0A0
EKDALTQYPRYKKYQ	BACH2	221	Q9BYV9
TQYPRYKKYQLACTK	BACH2	226	Q9BYV9
YILKPYKKVQSRQYG	CFAP43	626	Q8NDM7
VNYPAKPTLYYKDKA	APOH	216	P02749
YKKAQRDLAYKPLYS	HSD3B1	331	P14060
KEEKGVTLLYYGRYN	ADGRD1	76	Q6QNK2
VPYLYTKNKKGYTFV	ADGB	1051	Q8N7X0
YQGTYIALSKYGRVK	FGF6	176	P10767
YLYRKGYLSLSKVVP	ABHD16A	81	O95870
YYPQLYKKVTGKEPA	CARD9	86	Q9H257
PAIGILKYKEKYYTF	CFAP206	436	Q8IYR0
SYKSREDGYYRKEPK	RBM20	751	Q5T481
KDSYARYLKSPIYKD	RGS9	401	O75916
SGRGKRYSYKLPQEY	ADAMTS19	311	Q8TE59
IKVPKSRYLGYIKDY	KAT2A	631	Q92830
GPKIDAVFYSKNKYY	MMP12	426	P39900
LPFKLEKTYGNYYKL	PCDHGA11	391	Q9Y5H2
KKNRYKDILPYDYSR	PTPN22	56	Q9Y2R2
VKIYKYEGVRGLYKG	SLC25A32	171	Q9H2D1
YRKILKGKYNYTGEP	PSKH2	271	Q96QS6
KYYIYGEPRKLITQD	MAGEB5	166	Q9BZ81
GRYLETYKAYEQKPA	ERCC1	206	P07992
KTKKPRSAYLLYYYD	HMGXB3	41	Q12766
PTYKEEVKSYYKAIR	PLXNC1	1476	O60486
RNKPRYPKASVQYYK	LCTL	481	Q6UWM7
YPKASVQYYKKIIIA	LCTL	486	Q6UWM7
LYTYPQKDGKYRLKN	FGD5	1141	Q6ZNL6
KSVLPKSIYDYYRSG	HAO1	16	Q9UJM8
KVYKAKYPIVGYTAR	NENF	131	Q9UMX5
KAKRKGYYDFPAVET	KIAA1549L	1411	Q6ZVL6
KFLPYSYFSKEAARK	OSBP2	716	Q969R2
FLEKYPLSQYKYIRS	PIK3CA	261	P42336
KSDSGKPYYYNSQTK	PRPF40A	191	O75400
KNQGYYDYVKPRLRT	OGDH	961	Q02218
YNKAISYLATVPKYR	DNAJC25	171	Q9H1X3
RIGSPEYIKSYKIAY	EDIL3	236	O43854
KPYKTRNDGKLYDAY	IL1RL1	366	Q01638
YAKNKYLAKGGSVYP	PRMT3	346	O60678
KTYNYPKYRAEALLS	CDK16	396	Q00536
RADNPGKYKKKSHYY	CCNL2	476	Q96S94
RKKKPYNSNIGFYTK	GALNT17	381	Q6IS24
YDVVYLKVAKPSNAY	DLG4	236	P78352
SKQYYLKQSRYLPGV	MAK	476	P20794
FGIYQKYPVKYRSGK	ITLN2	196	Q8WWU7
KYIPKQSFLTRKYYF	EMC3	66	Q9P0I2
KRYAEKYSGVLDSPY	FIGNL2	61	A6NMB9
KDYGGYLSTYILPAK	DPP6	711	P42658
SSVEYGKKKRRYLPY	FADS3	246	Q9Y5Q0
SKINYGGDIPRKYYV	SEC14L2	256	O76054
TKINYGGEVPKSYYL	SEC14L4	256	Q9UDX3
TKINYGGEVPKSYYL	SEC14L6	256	B5MCN3
YNAYRKAASVIAKYP	POLB	36	P06746
KVYFPYLLISKKRYA	POLD1	796	P28340
NIVKKPGNIYYLYKR	C1orf50	111	Q9BV19
KYFKNGEKYAVPVLR	PDIA5	356	Q14554
SELIYAVSKKKYKYP	SULT6B1	76	Q6IMI4
AKRFKLNYATYGKQP	TRNAU1AP	76	Q9NX07
QILLKGYGEYPTKYR	TBC1D31	416	Q96DN5
YNTRKEKEGPSKYFF	SLC9C1	586	Q4G0N8
FKKGDPVYVYYKLAR	MIA3	66	Q5JRA6
ERNKKKQLPYYYLSP	ALOX5	651	P09917
LYPKSKRRYDTYNIA	SAMD9	1181	Q5K651
REDLPYHYYDKKGTK	ST8SIA3	331	O43173
KPKSYEAFYARARAK	TANC1	1366	Q9C0D5
KALELKPKSYEAYYA	TANC2	1316	Q9HCD6
KPKSYEAYYARARAK	TANC2	1321	Q9HCD6
VLPQTILYKYYERKA	RNF216	576	Q9NWF9
GAYLKGKKYRPLFDY	IARS1	281	P41252
KYLAKGTNIYVPSSY	SLF2	141	Q8IX21
YKVFSKFYLTYPTKR	KCTD14	226	Q9BQ13
PNYKKNGKLYVSYTT	HHIP	291	Q96QV1
DVYALKKPYGVLYKK	RPF2	51	Q9H7B2
PKAYYSPVGKKNIYL	ADAM17	366	P78536
YFQKYGYSPRVKKNS	SKA3	96	Q8IX90
SRQHLEKYPDYKYKP	SOX13	481	Q9UN79
KASPEYLKVKYLREY	TTC13	421	Q8NBP0
KKPYECKQYGEGLSY	ZNF700	331	Q9H0M5
ARKIIYTGEKPYKYE	ZNF92	526	Q03936
PAVKNSYYPRKYDAK	NUFIP1	136	Q9UHK0
GNPEIDNKKYYKYSK	RNASEH2B	146	Q5TBB1
KTPDGKVYYYNARTR	TCERG1	141	O14776
PTLYIIKYDGKDSVY	SPIN4	71	Q56A73
SLIKYTPLTYNKKYT	SLC6A13	511	Q9NSD5
YTYYYGKRKKISKPP	SFMBT2	661	Q5VUG0
KYSIKYNPGYVLASR	XRN1	906	Q8IZH2
VPFSKRYLKYLTKKY	RPL22	76	P35268
KVYATLEAYTKQKYP	RXRG	396	P48443
YRYYTPAKRKKDFTD	SPATA7	256	Q9P0W8
AEKKKVGNYYTTPIY	YJU2B	71	P13994
DPGVKSVTKIYNYYK	TALDO1	211	P37837
LLKESKYYTRKIYPV	UGT1A6	66	P19224
LGERPYKYLKYSKSF	ZSCAN29	646	Q8IWY8
YKYLKYSKSFGPNSL	ZSCAN29	651	Q8IWY8
KYKNEGPDYRLYKSE	PLEKHA5	796	Q9HAU0
LGKKYRKYYYKSPKP	ZNF335	446	Q9H4Z2
LIKYDLQNLKPYTKY	PTPRC	441	P08575
KKQDYLQGAPYYLKD	USP40	1146	Q9NVE5
YKYPEGSRKERQVYS	TGM6	441	O95932
RYTKNKKTDKYSSYP	NAALAD2	526	Q9Y3Q0
KDPELLGYYIYSRKV	MYOM3	626	Q5VTT5
YKLEYNKAKPRGYTT	NEB	5476	P20929