Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

MECOM SUV39H1 NSD3

1.16e-0444433GO:0140938
GeneOntologyMolecularFunctionhistone H3K9me2 methyltransferase activity

MECOM SUV39H1

2.02e-0410432GO:0140947
GeneOntologyMolecularFunctionhistone H3K9 methyltransferase activity

MECOM SUV39H1

3.48e-0413432GO:0046974
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

MECOM SUV39H1 NSD3

4.23e-0468433GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

MECOM SUV39H1 NSD3

4.41e-0469433GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

MECOM SUV39H1 NSD3

4.80e-0471433GO:0042054
GeneOntologyMolecularFunctionzinc ion binding

RNF144B KDM5B ZNF346 ZMAT4 ZMYM1 ZFYVE1 NR1D2 SUV39H1

5.50e-04891438GO:0008270
GeneOntologyMolecularFunctionprotein methyltransferase activity

MECOM SUV39H1 NSD3

1.42e-03103433GO:0008276
GeneOntologyMolecularFunctionhistone modifying activity

MECOM KDM5B SUV39H1 NSD3

1.46e-03229434GO:0140993
GeneOntologyMolecularFunctionN-methyltransferase activity

MECOM SUV39H1 NSD3

1.50e-03105433GO:0008170
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

MECOM ZNF85 ZIK1 ZNF606 ZNF157 HOXD10 VEZF1 NR1D2 SUV39H1

3.38e-031459439GO:0000977
GeneOntologyMolecularFunctiontransition metal ion binding

RNF144B KDM5B ZNF346 ZMAT4 ZMYM1 ZFYVE1 NR1D2 SUV39H1

3.46e-031189438GO:0046914
GeneOntologyBiologicalProcessrenal system development

PCSK5 UMOD MECOM AMER1 ANGPT2 TACSTD2 EPCAM WNT2B

9.47e-07386428GO:0072001
GeneOntologyBiologicalProcesskidney development

PCSK5 UMOD AMER1 ANGPT2 TACSTD2 EPCAM WNT2B

9.19e-06372427GO:0001822
GeneOntologyBiologicalProcesstube development

PCSK5 TGFBR2 UMOD MECOM KDM5B ANGPT2 VEZF1 TACSTD2 EPCAM CCBE1 WNT2B

8.27e-0514024211GO:0035295
GeneOntologyBiologicalProcessregulation of cell motility

SELP PCSK5 TGFBR2 RFFL FBN2 ANGPT2 TACSTD2 EPCAM CCBE1 UNC5D

1.94e-0412804210GO:2000145
GeneOntologyBiologicalProcessregulation of locomotion

SELP PCSK5 TGFBR2 RFFL FBN2 ANGPT2 TACSTD2 EPCAM CCBE1 UNC5D

2.59e-0413274210GO:0040012
GeneOntologyBiologicalProcessstem cell proliferation

TGFBR2 MECOM EPCAM WNT2B

2.82e-04156424GO:0072089
GeneOntologyBiologicalProcesskidney epithelium development

UMOD TACSTD2 EPCAM WNT2B

3.25e-04162424GO:0072073
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

SELP TGFBR2 UMOD EPCAM UNC5D

4.18e-04313425GO:0098742
GeneOntologyBiologicalProcessnephron development

UMOD ANGPT2 TACSTD2 WNT2B

4.26e-04174424GO:0072006
GeneOntologyBiologicalProcesscellular response to starvation

MIOS ZFYVE1 SUV39H1 WNT2B

5.37e-04185424GO:0009267
GeneOntologyBiologicalProcessappendage morphogenesis

PCSK5 MECOM FBN2 HOXD10

5.37e-04185424GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

PCSK5 MECOM FBN2 HOXD10

5.37e-04185424GO:0035108
GeneOntologyBiologicalProcessregulation of cell migration

SELP PCSK5 TGFBR2 RFFL FBN2 ANGPT2 TACSTD2 CCBE1 UNC5D

6.17e-041211429GO:0030334
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

TGFBR2 KDM5B TACSTD2 WNT2B

6.93e-04198424GO:0048754
GeneOntologyBiologicalProcessregulation of integrin activation

SELP PCSK5

7.51e-0420422GO:0033623
GeneOntologyBiologicalProcessanimal organ morphogenesis

TGFBR2 MECOM KDM5B FBN2 HOXD10 TACSTD2 RHO WNT2B SLIT3

8.64e-041269429GO:0009887
GeneOntologyBiologicalProcessameboidal-type cell migration

TGFBR2 RFFL FBN2 ANGPT2 TACSTD2 CCBE1

1.04e-03577426GO:0001667
GeneOntologyBiologicalProcessregulation of branching involved in ureteric bud morphogenesis

TACSTD2 WNT2B

1.09e-0324422GO:0090189
GeneOntologyBiologicalProcesslimb development

PCSK5 MECOM FBN2 HOXD10

1.10e-03224424GO:0060173
GeneOntologyBiologicalProcessappendage development

PCSK5 MECOM FBN2 HOXD10

1.10e-03224424GO:0048736
GeneOntologyBiologicalProcessresponse to starvation

MIOS ZFYVE1 SUV39H1 WNT2B

1.19e-03229424GO:0042594
GeneOntologyBiologicalProcesslens development in camera-type eye

TGFBR2 KDM5B WNT2B

1.21e-03103423GO:0002088
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

TGFBR2 KDM5B TACSTD2 WNT2B

1.33e-03236424GO:0061138
GeneOntologyBiologicalProcessureteric bud development

TACSTD2 EPCAM WNT2B

1.35e-03107423GO:0001657
GeneOntologyBiologicalProcessmesonephric tubule development

TACSTD2 EPCAM WNT2B

1.46e-03110423GO:0072164
GeneOntologyBiologicalProcessmesonephric epithelium development

TACSTD2 EPCAM WNT2B

1.46e-03110423GO:0072163
GeneOntologyBiologicalProcessnephron tubule development

UMOD TACSTD2 WNT2B

1.46e-03110423GO:0072080
GeneOntologyBiologicalProcessatrioventricular valve morphogenesis

TGFBR2 SLIT3

1.48e-0328422GO:0003181
GeneOntologyBiologicalProcessmesonephros development

TACSTD2 EPCAM WNT2B

1.57e-03113423GO:0001823
GeneOntologyBiologicalProcessintegrin activation

SELP PCSK5

1.59e-0329422GO:0033622
GeneOntologyBiologicalProcessrenal tubule development

UMOD TACSTD2 WNT2B

1.70e-03116423GO:0061326
GeneOntologyBiologicalProcesstube morphogenesis

TGFBR2 MECOM KDM5B ANGPT2 VEZF1 TACSTD2 CCBE1 WNT2B

1.72e-031125428GO:0035239
GeneOntologyBiologicalProcessregulation of stem cell proliferation

TGFBR2 MECOM EPCAM

1.82e-03119423GO:0072091
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

TGFBR2 KDM5B TACSTD2 WNT2B

1.84e-03258424GO:0001763
GeneOntologyBiologicalProcessatrioventricular valve development

TGFBR2 SLIT3

1.93e-0332422GO:0003171
GeneOntologyBiologicalProcesscellular response to nutrient levels

MIOS ZFYVE1 SUV39H1 WNT2B

1.95e-03262424GO:0031669
DomainEGF

SELP PCSK5 UMOD FBN2 CCBE1 ATRNL1 SLIT3

1.00e-06235437SM00181
DomainEGF-like_dom

SELP PCSK5 UMOD FBN2 CCBE1 ATRNL1 SLIT3

1.47e-06249437IPR000742
DomainEGF_3

SELP UMOD FBN2 CCBE1 ATRNL1 SLIT3

1.54e-05235436PS50026
DomainEGF_1

SELP UMOD FBN2 CCBE1 ATRNL1 SLIT3

2.44e-05255436PS00022
DomainEGF-like_CS

SELP UMOD FBN2 CCBE1 ATRNL1 SLIT3

2.78e-05261436IPR013032
DomainEGF_2

SELP UMOD FBN2 CCBE1 ATRNL1 SLIT3

3.03e-05265436PS01186
DomainAbLIM_anchor

ABLIM2 ABLIM3

3.10e-054432PF16182
DomainAbLIM_anchor

ABLIM2 ABLIM3

3.10e-054432IPR032402
DomainEGF_Ca-bd_CS

UMOD FBN2 CCBE1 SLIT3

7.22e-0597434IPR018097
DomainEGF_CA

UMOD FBN2 CCBE1 SLIT3

7.82e-0599434PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

UMOD FBN2 CCBE1 SLIT3

1.02e-04106434IPR000152
DomainHP

ABLIM2 ABLIM3

1.44e-048432PS51089
Domain-

ABLIM2 ABLIM3

1.44e-0484321.10.950.10
DomainVHP

ABLIM2 ABLIM3

1.44e-048432PF02209
DomainVillin_headpiece

ABLIM2 ABLIM3

1.44e-048432IPR003128
DomainVHP

ABLIM2 ABLIM3

1.44e-048432SM00153
DomainEGF_CA

UMOD FBN2 CCBE1 SLIT3

1.76e-04122434SM00179
DomainEGF-like_Ca-bd_dom

UMOD FBN2 CCBE1 SLIT3

1.87e-04124434IPR001881
DomainZnf_FYVE_PHD

KDM5B RFFL ZFYVE1 NSD3

3.58e-04147434IPR011011
DomainZnf_C2H2-like

MECOM ZNF346 ZMAT4 ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

4.05e-04796438IPR015880
DomainZnf_C2H2

MECOM ZNF346 ZMAT4 ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

4.36e-04805438IPR007087
DomainZnF_C2H2

MECOM ZNF346 ZMAT4 ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

4.47e-04808438SM00355
DomainGrowth_fac_rcpt_

PCSK5 UMOD FBN2 SLIT3

4.49e-04156434IPR009030
DomainPost-SET_dom

SUV39H1 NSD3

6.09e-0416432IPR003616
DomainPostSET

SUV39H1 NSD3

6.09e-0416432SM00508
DomainPOST_SET

SUV39H1 NSD3

6.09e-0416432PS50868
DomainTY

TACSTD2 EPCAM

6.89e-0417432SM00211
Domain-

TACSTD2 EPCAM

6.89e-04174324.10.800.10
DomainTHYROGLOBULIN_1_2

TACSTD2 EPCAM

6.89e-0417432PS51162
DomainThyroglobulin_1

TACSTD2 EPCAM

6.89e-0417432IPR000716
DomainThyroglobulin_1

TACSTD2 EPCAM

6.89e-0417432PF00086
DomainTHYROGLOBULIN_1_1

TACSTD2 EPCAM

6.89e-0417432PS00484
DomainZF_MATRIN

ZNF346 ZMAT4

7.74e-0418432PS50171
DomainC_TYPE_LECTIN_1

SELP CLEC9A ATRNL1

8.25e-0480433PS00615
DomainLectin_C

SELP CLEC9A ATRNL1

9.51e-0484433PF00059
DomainCLECT

SELP CLEC9A ATRNL1

9.51e-0484433SM00034
DomainC_TYPE_LECTIN_2

SELP CLEC9A ATRNL1

9.84e-0485433PS50041
DomainC-type_lectin-like

SELP CLEC9A ATRNL1

1.02e-0386433IPR001304
DomainEGF_CA

UMOD FBN2 CCBE1

1.02e-0386433PF07645
Domain-

SELP CLEC9A ATRNL1

1.44e-03974333.10.100.10
DomainC-type_lectin-like/link

SELP CLEC9A ATRNL1

1.53e-0399433IPR016186
DomainASX_HYDROXYL

UMOD FBN2 CCBE1

1.57e-03100433PS00010
DomainCTDL_fold

SELP CLEC9A ATRNL1

1.91e-03107433IPR016187
DomainZnF_U1

ZNF346 ZMAT4

2.02e-0329432SM00451
DomainZnf_U1

ZNF346 ZMAT4

2.02e-0329432IPR003604
DomainEGF

SELP UMOD SLIT3

3.04e-03126433PF00008
DomainZnf_FYVE

RFFL ZFYVE1

3.45e-0338432IPR000306
Domain-

RNF144B KDM5B RFFL ZFYVE1 NSD3

3.56e-034494353.30.40.10
DomainZF_FYVE

RFFL ZFYVE1

3.82e-0340432PS50178
DomainZnf_RING/FYVE/PHD

RNF144B KDM5B RFFL ZFYVE1 NSD3

3.91e-03459435IPR013083
DomainSET

SUV39H1 NSD3

4.01e-0341432PF00856
Domain-

MECOM ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

4.38e-036794363.30.160.60
DomainC-type_lectin_CS

SELP CLEC9A

4.40e-0343432IPR018378
Domainzf-C2H2

MECOM ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

4.83e-03693436PF00096
DomainZnf_C2H2/integrase_DNA-bd

MECOM ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

4.86e-03694436IPR013087
DomainSET

SUV39H1 NSD3

5.03e-0346432SM00317
Domainzf-C2H2_6

MECOM ZNF85 ZNF606 ZNF157

5.77e-03314434PF13912
DomainSET_dom

SUV39H1 NSD3

5.91e-0350432IPR001214
DomainSET

SUV39H1 NSD3

5.91e-0350432PS50280
DomainZINC_FINGER_C2H2_2

MECOM ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

8.24e-03775436PS50157
DomainZINC_FINGER_C2H2_1

MECOM ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

8.34e-03777436PS00028
DomainKRAB

ZNF85 ZIK1 ZNF606 ZNF157

9.09e-03358434PS50805
DomainKRAB

ZNF85 ZIK1 ZNF606 ZNF157

9.09e-03358434PF01352
DomainZinc_finger_PHD-type_CS

KDM5B NSD3

9.82e-0365432IPR019786
DomainKRAB

ZNF85 ZIK1 ZNF606 ZNF157

1.01e-02369434SM00349
DomainKRAB

ZNF85 ZIK1 ZNF606 ZNF157

1.02e-02370434IPR001909
DomainLIM

ABLIM2 ABLIM3

1.10e-0269432PF00412
Domain-

ABLIM2 ABLIM3

1.13e-02704322.10.110.10
PathwayREACTOME_NETRIN_1_SIGNALING

ABLIM2 ABLIM3 UNC5D SLIT3

3.16e-0644334M875
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

TGFBR2 FBN2 ANGPT2

2.60e-0525333M39713
PathwayKEGG_AXON_GUIDANCE

ABLIM2 ABLIM3 UNC5D SLIT3

2.23e-04129334M5539
PathwayREACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING

ABLIM2 ABLIM3

4.75e-0414332M889
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

MECOM SUV39H1 NSD3

5.75e-0470333M27231
PathwayWP_AXON_GUIDANCE

ABLIM3 UNC5D SLIT3

6.24e-0472333M48335
Pubmed

Expression profile of the GA733 gene family in colorectal cancer: correlation with clinicopathological parameters.

TACSTD2 EPCAM

1.49e-06243226600538
Pubmed

Spatial and temporal expression patterns of the epithelial cell adhesion molecule (EpCAM/EGP-2) in developing and adult kidneys.

UMOD EPCAM

1.49e-06243218025791
Pubmed

Single nucleotide polymorphisms of the EpCAM-coding gene TACSTD1 in patients with ovarian cancer and their potential translational aspects.

TACSTD2 EPCAM

1.49e-06243226115884
Pubmed

EVI1 recruits the histone methyltransferase SUV39H1 for transcription repression.

MECOM SUV39H1

1.49e-06243218655152
Pubmed

Retroposition in a family of carcinoma-associated antigen genes.

TACSTD2 EPCAM

1.49e-0624328382772
Pubmed

Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization.

TACSTD2 EPCAM

1.49e-06243211306819
Pubmed

Overexpression of EpCAM and Trop2 in pituitary adenomas.

TACSTD2 EPCAM

1.49e-06243225550831
Pubmed

EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice.

TACSTD2 EPCAM

1.49e-06243235730316
Pubmed

EpCAM cellular functions in adhesion and migration, and potential impact on invasion: A critical review.

TACSTD2 EPCAM

1.49e-06243232976980
Pubmed

Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733.

TACSTD2 EPCAM

1.49e-0624322911574
Pubmed

Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins.

TACSTD2 EPCAM

4.48e-06343232326212
Pubmed

EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization.

MECOM SUV39H1

4.48e-06343219776757
Pubmed

A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.

MECOM SUV39H1

4.48e-06343218619962
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

TGFBR2 FBN2

8.94e-06443216835936
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

TGFBR2 ZIK1 UNC5D WNT2B SLIT3

1.45e-0525143529031500
Pubmed

Serum response factor is required for sprouting angiogenesis and vascular integrity.

TGFBR2 ANGPT2 VEZF1

2.10e-054343318804439
Pubmed

Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.

ABLIM2 ABLIM3

2.23e-05643217194709
Pubmed

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development.

TACSTD2 EPCAM

2.23e-05643222194864
Pubmed

Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation.

UMOD ANGPT2

2.23e-05643210446940
Pubmed

Trop2 marks transient gastric fetal epithelium and adult regenerating cells after epithelial damage.

TACSTD2 EPCAM

2.23e-05643226989172
Pubmed

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.

TGFBR2 FBN2 TACSTD2

3.95e-055343333153107
Pubmed

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.

MECOM ANGPT2

6.68e-051043215889140
Pubmed

Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis.

TGFBR2 ANGPT2

8.15e-051143210716993
Pubmed

VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.

PCSK5 HOXD10

9.78e-051243218519639
Pubmed

A trans-acting protein effect causes severe eye malformation in the Mp mouse.

FBN2 RHO

1.15e-041343224348270
Pubmed

Angiopoietin-1 Is Required for Vortex Vein and Choriocapillaris Development in Mice.

SELP ANGPT2

1.35e-041443236172864
Pubmed

Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development.

TACSTD2 EPCAM

1.55e-041543228077488
Pubmed

Pten Regulates Retinal Amacrine Cell Number by Modulating Akt, Tgfβ, and Erk Signaling.

TGFBR2 RHO

2.26e-041843227605619
Pubmed

YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.

TACSTD2 EPCAM

2.26e-041843229249464
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

PCSK5 ANGPT2 OLFML2B SLIT3

2.50e-0424843424006456
Pubmed

A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.

TGFBR2 ANGPT2

2.80e-042043212588999
Pubmed

FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.

UNC5D SLIT3

2.80e-042043230392794
Pubmed

Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells.

TGFBR2 ANGPT2

3.09e-042143221593423
Pubmed

Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180.

TGFBR2 ANGPT2

3.09e-042143218508041
Pubmed

Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.

UMOD ANGPT2

3.72e-042343229237738
Pubmed

SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.

TGFBR2 ANGPT2

5.14e-042743233227706
Pubmed

Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

TGFBR2 MECOM

5.14e-042743224586749
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

UNC5D WNT2B SLIT3

5.15e-0412643316284245
Pubmed

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth.

ANGPT2 EPCAM

5.53e-042843234963058
Pubmed

Dosage-dependent requirement for mouse Vezf1 in vascular system development.

ANGPT2 VEZF1

5.93e-042943215882861
Pubmed

Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism.

TGFBR2 ANGPT2

5.93e-042943223565059
Pubmed

Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches.

EPCAM WNT2B

6.35e-043043231953387
Pubmed

Heritable Thoracic Aortic Disease Overview

TGFBR2 FBN2

6.35e-043043220301299
Pubmed

Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent.

TACSTD2 EPCAM

6.79e-043143236656901
Pubmed

Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.

KDM5B SUV39H1

7.23e-043243214613977
Pubmed

Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant.

HOXD10 RHO

7.23e-043243236737666
Pubmed

The Trim family of genes and the retina: Expression and functional characterization.

UNC5D RHO

7.69e-043343230208054
Pubmed

Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier.

TGFBR2 ANGPT2

8.17e-043443226120030
Pubmed

A Y2H-seq approach defines the human protein methyltransferase interactome.

MECOM NR1D2 SUV39H1 NSD3

8.38e-0434243423455924
Pubmed

GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis.

TGFBR2 WNT2B

8.66e-043543231167144
Pubmed

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.

UMOD MECOM

9.67e-043743222797727
Cytoband2q31.1

CHN1 HOXD10

2.85e-03844322q31.1
Cytoband19q13.43

ZIK1 NLRP8

3.05e-038743219q13.43
CytobandEnsembl 112 genes in cytogenetic band chr8p11

ZMAT4 NSD3

4.24e-03103432chr8p11
CytobandEnsembl 112 genes in cytogenetic band chr3p24

TGFBR2 NR1D2

5.08e-03113432chr3p24
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

MECOM SUV39H1 NSD3

3.19e-0534333487
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

MECOM ZNF85 ZIK1 ZNF606 ZNF157 VEZF1

1.70e-0371833628
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELP ATRNL1

2.53e-03413321298
GeneFamilyLIM domain containing

ABLIM2 ABLIM3

5.18e-03593321218
GeneFamilyADAM metallopeptidase domain containing|CD molecules

SELP CLEC9A SLAMF7 EPCAM

5.52e-03394334471
GeneFamilyPHD finger proteins

KDM5B NSD3

1.17e-029033288
CoexpressionDUTERTRE_ESTRADIOL_RESPONSE_24HR_DN

RNF144B MIOS TGFBR2 MECOM KDM5B FBN2 ABLIM3 TACSTD2

1.42e-06504438M2157
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2

RNF144B ZMAT4 ABLIM3 EPCAM OLFML2B WNT2B SLIT3

1.43e-05493437M1951
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2

RNF144B ZMAT4 ABLIM3 EPCAM OLFML2B WNT2B SLIT3

1.65e-05504437MM830
CoexpressionBOQUEST_STEM_CELL_DN

SELP MECOM ANGPT2 ABLIM3 TACSTD2

2.83e-05218435M1578
CoexpressionCERVERA_SDHB_TARGETS_1_UP

PCSK5 TMEM156 ABLIM2 WNT2B

4.49e-05120434M15549
CoexpressionTRAVAGLINI_LUNG_ARTERY_CELL

SELP RNF144B PCSK5 MECOM

6.32e-05131434M41662
CoexpressionAtlasBM Top 100 - kidney medulla

UMOD MECOM HOXD10 TACSTD2 EPCAM

3.45e-0774425BM Top 100 - kidney medulla
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

ZNF346 AMER1 FBN2 CCBE1 ATRNL1 WNT2B

7.31e-06240426gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_1000
CoexpressionAtlasBM Top 100 - endometrium

MECOM HOXD10 TACSTD2 EPCAM

8.72e-0666424BM Top 100 - endometrium
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

PCSK5 ZIK1 AMER1 FBN2 HOXD10 VEZF1 CCBE1 OLFML2B ATRNL1

1.69e-05777429gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

PCSK5 ZIK1 AMER1 FBN2 HOXD10 ATRNL1

3.11e-05310426gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

TGFBR2 UMOD MECOM ZMAT4 ANGPT2 CHN1 VEZF1 OLFML2B NR1D2

4.19e-05872429gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#2_top-relative-expression-ranked_1000

MECOM ZMAT4 ANGPT2 CHN1 VEZF1 OLFML2B

5.92e-05348426gudmap_kidney_adult_Mesangium_Meis_k2_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_CardioEndothel_top-relative-expression-ranked_1000

SELP RNF144B TGFBR2 TMEM156 MECOM ANGPT2 ABLIM3 TACSTD2 CCBE1

1.02e-04978429PCBC_ctl_CardioEndothel_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

ZNF346 AMER1 FBN2 HOXD10 CCBE1 OLFML2B ATRNL1 WNT2B

1.45e-04797428gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

UMOD MECOM ANGPT2 TACSTD2 EPCAM SLIT3

2.59e-04456426gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_200

MECOM HOXD10 TACSTD2 EPCAM

3.35e-04168424gudmap_kidney_e15.5_Podocyte_MafB_200
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

UMOD MECOM ANGPT2 HOXD10 TACSTD2 EPCAM OLFML2B SLIT3

3.43e-04905428gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlasBM Top 100 - stomach pyloric

MECOM TACSTD2 EPCAM

3.44e-0469423BM Top 100 - stomach pyloric
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_200

MECOM FBN2 HOXD10 EPCAM

3.91e-04175424gudmap_kidney_P4_CapMesRenVes_Crym_200
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_CardioEndothel_top-relative-expression-ranked_500

SELP RNF144B TMEM156 ANGPT2 ABLIM3 TACSTD2

4.01e-04495426PCBC_ctl_CardioEndothel_500
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_200

MECOM ANGPT2 TACSTD2 SLIT3

4.08e-04177424gudmap_kidney_P0_JuxtaGlom_Ren1_200
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000

MECOM ANGPT2 NSD3 SLIT3

4.26e-04179424gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN2 ANGPT2 CHN1 OLFML2B ATRNL1

8.95e-071834358a799807fbf24456a9811e0c64068187940a2f71
ToppCellControl-Myeloid-DC1|Myeloid / Condition, Lineage and Cell class

TMEM156 CLEC9A SLAMF7 TACSTD2 EPCAM

9.19e-07184435b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SELP RNF144B MECOM CHN1 WNT2B

9.44e-07185435a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF144B CLEC9A SLAMF7 TACSTD2 EPCAM

9.96e-071874353d4e81183cb7f6522ae654ddac494662402aa86d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 TACSTD2 EPCAM

1.02e-06188435d2d2b6c49448da24f457cedcd213f68841834a99
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 TACSTD2 EPCAM

1.02e-06188435ab6fa1beff91584d9303c2a33735de89aae8d5cd
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

SELP RNF144B MECOM CHN1 WNT2B

1.05e-06189435fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B TACSTD2 EPCAM UNC5D SLIT3

1.08e-06190435b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFBR2 ANGPT2 ABLIM2 HOXD10 ABLIM3

1.08e-06190435a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

SELP RNF144B MECOM CHN1 WNT2B

1.08e-06190435f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFBR2 ANGPT2 ABLIM2 HOXD10 ABLIM3

1.08e-061904350bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFBR2 ANGPT2 ABLIM2 HOXD10 ABLIM3

1.08e-0619043526e2237f65cb43723c5da853831b40df2982d6e4
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR2 ANGPT2 ABLIM2 HOXD10 ABLIM3

1.10e-0619143548823a97c38263f2c6e58348214f5b62773a6368
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SELP RNF144B PCSK5 MECOM WNT2B

1.10e-06191435ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR2 ANGPT2 ABLIM2 HOXD10 ABLIM3

1.10e-061914350eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 TACSTD2 EPCAM

1.13e-061924356fb56d062c35617b18b927704bf5fba894faed81
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 TACSTD2 EPCAM

1.16e-06193435b397c14ac1e34c6be3f25d4417d200bc518d3048
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 TACSTD2 EPCAM

1.16e-06193435241a60d1f0d5832638fb3e1e4b7afa7387ea3c75
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 TACSTD2 EPCAM

1.16e-06193435fa8bcf2a5ab7b08fae98a1466a936995142b4309
ToppCelldroplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B MECOM KDM5B TACSTD2 EPCAM

1.22e-06195435d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SELP CHN1 CCBE1 ATRNL1 SLIT3

1.39e-0620043516a3685c41194a0a4a772e4eee372160263480e0
ToppCellLA-10._Endothelium_II|LA / Chamber and Cluster_Paper

SELP RNF144B MECOM TACSTD2

8.48e-06134434048fa6ccf305d22d9a53db4ab385f39f558010d8
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ZMAT4 CHN1 ABLIM3 CCBE1

1.04e-051414347ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCell368C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TMEM156 CLEC9A SLAMF7 TACSTD2

1.75e-051614341011094c54381d52566e24c92f89f2efc2aa3eea
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM2 CCBE1 ATRNL1 SLIT3

2.11e-05169434a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM2 CCBE1 ATRNL1 SLIT3

2.16e-05170434fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM2 CCBE1 ATRNL1 SLIT3

2.16e-0517043403044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 CCBE1 OLFML2B SLIT3

2.16e-05170434417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|356C / Donor, Lineage, Cell class and subclass (all cells)

TMEM156 PINLYP CHN1 NSD3

2.32e-05173434e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFBR2 ZMAT4 ANGPT2 ABLIM3

2.32e-051734347dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLEC9A SLAMF7 TACSTD2 EPCAM

2.37e-05174434991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP ANGPT2 CHN1 TACSTD2

2.37e-05174434eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CLEC9A SLAMF7 TACSTD2 EPCAM

2.37e-05174434c8cec89369cf3896c5626e447051e76a142cb6df
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP ANGPT2 CHN1 TACSTD2

2.37e-0517443432fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHN1 RHO WNT2B SLIT3

2.42e-0517543459249c9e83952d7277010e7be3c779e26399eb5d
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMAT4 TACSTD2 UNC5D SUV39H1

2.42e-0517543496219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMAT4 TACSTD2 UNC5D SUV39H1

2.42e-05175434cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHN1 RHO WNT2B SLIT3

2.42e-05175434b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ANGPT2 CHN1 OLFML2B SLIT3

2.48e-051764342015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

TGFBR2 OLFML2B ATRNL1 SLIT3

2.65e-05179434e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RNF144B PCSK5 MECOM ANGPT2

2.65e-051794342a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABLIM2 ABLIM3 CCBE1 SLIT3

2.71e-0518043408ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABLIM2 ABLIM3 CCBE1 SLIT3

2.71e-051804349b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABLIM2 ABLIM3 CCBE1 SLIT3

2.77e-051814349e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellHealthy-multiplets|World / disease group, cell group and cell class

CLEC9A SLAMF7 TACSTD2 EPCAM

2.77e-05181434f8dbac3cd500cc8d80853312b00d124c27b8fd85
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

CLEC9A SLAMF7 TACSTD2 EPCAM

2.77e-051814345a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-DC-cDC2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF144B CLEC9A TACSTD2 ATRNL1

2.83e-051824341d37c486173cc4629842893ddd5033987c04086f
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-DC-cDC2-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF144B CLEC9A TACSTD2 ATRNL1

2.83e-05182434aef67bdc6937b315522d39959e26c9b0acf7ab52
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-DC|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF144B CLEC9A TACSTD2 ATRNL1

2.83e-05182434087c9f88daf08f5d688b728c2386f91f210d2255
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PCSK5 MECOM HOXD10

2.83e-05182434ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 EPCAM

2.83e-05182434ccfee33de0faebbe69099d4ff3c3971f6a708b99
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PCSK5 MECOM HOXD10

2.83e-0518243447ff6b4002a4167412c79210651316d1342503f9
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP PCSK5 MECOM ZIK1

2.89e-0518343412e876d6205af8aad74265c668b5e95b9e7487f3
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TGFBR2 ANGPT2 ABLIM2 HOXD10

2.89e-0518343489727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TGFBR2 ANGPT2 ABLIM2 HOXD10

2.89e-05183434113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANGPT2 CHN1 OLFML2B ATRNL1

2.95e-05184434689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

TMEM156 CLEC9A SLAMF7 TACSTD2

2.95e-05184434c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

ABLIM2 CHN1 OLFML2B SLIT3

2.95e-05184434a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM HOXD10 TACSTD2 EPCAM

2.95e-051844349690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TMEM156 CLEC9A SLAMF7 TACSTD2

2.95e-05184434315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCellnormal-na-Lymphocytic-lymphocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ZNF346 ZIK1 SLAMF7 ZFYVE1

2.95e-051844342c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 EPCAM

2.95e-051844348939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PCSK5 FBN2 CHN1 OLFML2B

3.01e-05185434427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 EPCAM

3.01e-05185434af86e75096c1812ae27a78405355957ee8043d84
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RNF144B PCSK5 MECOM SLAMF7

3.01e-05185434b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RNF144B PCSK5 MECOM SLAMF7

3.01e-05185434d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD HOXD10 TACSTD2 EPCAM

3.08e-051864347380af16e537cc49a2bb24ac50663d13c38459a7
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD HOXD10 TACSTD2 EPCAM

3.08e-05186434d56ccbe26bfddba0e2c54e7c7a5ca7f46fd3d891
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELP PCSK5 MECOM ABLIM2

3.08e-05186434c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANGPT2 OLFML2B UNC5D SLIT3

3.08e-051864344780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANGPT2 OLFML2B UNC5D SLIT3

3.08e-05186434a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM HOXD10 TACSTD2 EPCAM

3.08e-05186434b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MECOM ABLIM3 TACSTD2 EPCAM

3.14e-05187434baff4edc1bf64e3e03864a434fa47075ff7372fd
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

HOXD10 CCBE1 ATRNL1 SLIT3

3.14e-0518743476bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

RNF144B PCSK5 MECOM ANGPT2

3.14e-0518743440ffc06a3e3251d9b12da390210d3e045af7537a
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B MECOM KDM5B EPCAM

3.14e-05187434aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

SELP RNF144B MECOM CHN1

3.14e-0518743481affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

SELP MECOM CHN1 WNT2B

3.21e-05188434eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 EPCAM

3.27e-05189434e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UMOD MECOM HOXD10 EPCAM

3.27e-05189434ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SELP MECOM CHN1 WNT2B

3.34e-0519043407b675befcd1d0a9c90cb17b5d22323468325d51
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM HOXD10 TACSTD2 EPCAM

3.34e-05190434c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B TACSTD2 EPCAM SLIT3

3.34e-05190434a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM HOXD10 TACSTD2 EPCAM

3.34e-05190434d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SELP MECOM CHN1 WNT2B

3.41e-0519143450601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCellE15.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MECOM FBN2 TACSTD2 EPCAM

3.41e-05191434402c341b00f98e8215458766b3c219fff8dcb447
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP MECOM HOXD10 ABLIM3

3.48e-05192434945153c41dde6e90d103206955e1707b54eb0665
ToppCellE15.5-Epithelial|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MECOM FBN2 TACSTD2 EPCAM

3.48e-051924343f2ecd428c0c608d7bbd7b403a07399b87761338
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP MECOM HOXD10 ABLIM3

3.48e-051924346ab50579c63f31ca2cd41063a99b129f11c07510
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SELP RNF144B PCSK5 MECOM

3.48e-051924347e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell367C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TMEM156 CLEC9A SLAMF7 TACSTD2

3.48e-05192434877aaf61d8fc40e7013944a0180306dd0bb0557f
ToppCellE15.5-Epithelial-alveolar_epithelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MECOM FBN2 TACSTD2 EPCAM

3.48e-05192434567f4355a01aae1f2eafc16fe86d1538a62030ab
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM HOXD10 TACSTD2 EPCAM

3.55e-05193434536b277d90070c4571c592a3c6323b4bf4819f67
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM HOXD10 TACSTD2 EPCAM

3.55e-051934340499611c21d283321ef6dd24add154dea48da1b7
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM KDM5B TACSTD2 EPCAM

3.55e-05193434268925bfe85fb94a93a4ff8fe078d692df888140
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MECOM KDM5B TACSTD2 EPCAM

3.55e-05193434ee91a796d0f6d4cee7a93a525689e716fdceeda5
ToppCellLAM-Myeloid-DC|Myeloid / Condition, Lineage and Cell class

TMEM156 CLEC9A TACSTD2 OLFML2B

3.55e-05193434f665cce40053ae5d6e28f9f70ddf78e8598c9514
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM HOXD10 TACSTD2 EPCAM

3.55e-0519343446d5d1f8150ebbc7f1941b96ab184491e5c1210b
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B MECOM TACSTD2 EPCAM

3.63e-051944341531dcace28a14bd700e909a027426a8cee20337
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CHN1 ABLIM3 CCBE1 SLIT3

3.63e-05194434b1bb0f846d2865efdd9bc8842b16b9d069785882
DrugSpurr resin

PCSK5 ZNF157 TACSTD2 EPCAM

6.45e-0664434CID006449895
DiseaseLower Extremity Deformities, Congenital

PCSK5 HOXD10

1.98e-062422C0431943
DiseaseLynch Syndrome

TGFBR2 EPCAM

7.08e-059422C4552100
Diseasemembranoproliferative glomerulonephritis (implicated_via_orthology)

TGFBR2 ANGPT2

8.84e-0510422DOID:2920 (implicated_via_orthology)
DiseaseDiuretic use measurement

UMOD MECOM FBN2 WNT2B

9.81e-05169424EFO_0009928
Diseasesevere aplastic anemia

ZMAT4 FBN2

2.05e-0415422EFO_0006927
DiseaseCalcium channel blocker use measurement

UMOD MECOM FBN2 WNT2B

2.38e-04213424EFO_0009930
Diseaseunipolar depression, bipolar disorder, schizophrenia

PCSK5 CCBE1

3.70e-0420422EFO_0003761, MONDO_0004985, MONDO_0005090
DiseaseBeta blocking agent use measurement

UMOD FBN2 WNT2B

5.78e-04114423EFO_0009929
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

TGFBR2 EPCAM

6.29e-0426422C0009405
DiseaseHereditary non-polyposis colorectal cancer syndrome

TGFBR2 EPCAM

6.79e-0427422C1112155
Diseaseintraocular pressure measurement

PCSK5 MECOM FBN2 ANGPT2 WNT2B

7.53e-04509425EFO_0004695
DiseaseHereditary Nonpolyposis Colorectal Cancer

TGFBR2 EPCAM

7.84e-0429422C1333990
Diseaseelectrocardiography

RNF144B RFFL ABLIM3 CCBE1 OLFML2B

9.02e-04530425EFO_0004327
Diseasemean arterial pressure, unipolar depression

MECOM WNT2B

9.55e-0432422EFO_0003761, EFO_0006340
Diseaseparasitemia measurement

OLFML2B NR1D2

1.28e-0337422EFO_0005528
DiseaseColonic Neoplasms

TGFBR2 MECOM KDM5B

1.33e-03152423C0009375
DiseaseMalignant tumor of colon

TGFBR2 MECOM KDM5B

1.51e-03159423C0007102
Diseasemyocardial infarction (biomarker_via_orthology)

SELP TGFBR2 ANGPT2

1.54e-03160423DOID:5844 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KAKQCNGTSMCWCVN

EPCAM

106

P16422
KECVCQTCSQSMASS

ABLIM3

126

O94929
KDGDNDKCICKCSQM

ANGPT2

426

O15123
EGTCSKKDQSTCLMQ

AMER1

706

Q5JTC6
RVTFNGKECMCQKCS

ABLIM2

121

Q6H8Q1
KQFRNCMLTTICCGK

RHO

311

P08100
CRTQIKCKDCGQMFS

MECOM

401

Q03112
KMTTLQECQCIFCTA

RNF144B

41

Q7Z419
NCCQDMISALCKNKT

NLRP8

911

Q86W28
AICSGADLCKKCQMQ

PCSK5

1236

Q92824
GQMKTCSSDKDTCVL

PINLYP

41

A6NC86
QCVKCKTTCFMSAIS

KDM5B

691

Q9UGL1
NMVKAGTCCATCKEF

CCBE1

191

Q6UXH8
CSFTTNIKEESNCCM

HOXD10

101

P28358
CDDKKCISANSNCSM

ATRNL1

686

Q5VV63
ASCQDMSCSKQGECL

SELP

161

P16109
CGSKSIQQCSVRCMN

FBN2

141

P35556
NVTKRMCCCTYNVGK

FBN2

1756

P35556
CADCGLNVHKQCSKM

CHN1

236

P15882
CQQCRFKKCLSVGMS

NR1D2

156

Q14995
CKKNFCMTCSSQVGN

RFFL

66

Q8WZ73
QDNCTCPTNKMTVCS

TACSTD2

31

P09758
CDNQKSCMSNCSITS

TGFBR2

61

P37173
VKAMSEGSDCQCKCV

OLFML2B

66

Q68BL8
MAENLKGCSVCCKSS

SUV39H1

1

O43463
SNKCSGACCLVMVIS

CLEC9A

26

Q6UXN8
TCQDITGEFKMCSSC

TMEM156

86

Q8N614
KCVATGTSYMCKCAE

SLIT3

1381

O75094
CSECGKIFSMKKSLC

ZNF157

416

P51786
CNTCKQGISKTCMSE

VEZF1

316

Q14119
CDTMNEKCKPTCSGT

UMOD

571

P07911
VSACTCKCMQLDTTG

MIOS

851

Q9NXC5
KAGSSTQKTQSCEMC

ZIK1

91

Q3SY52
CTAICKSQSPTCQMC

TSPAN31

146

Q12999
KNGTCVTNLTCCMEH

SLAMF7

141

Q9NQ25
CEGMSVQKITCTSLC

UNC5D

291

Q6UXZ4
GMSKKDTVCQICESS

NSD3

696

Q9BZ95
SLCLSCGVGCKKSMN

ZFYVE1

431

Q9HBF4
DKNQCCPICNMTFSS

ZNF346

131

Q9UL40
CTKCGKSFGMISCLT

ZNF85

176

Q03923
ICTNSILTKCSMCQK

ZMYM1

181

Q5SVZ6
VDKNKCCTLCNMSFT

ZMAT4

71

Q9H898
SKTSKGTDGCEIMCC

WNT2B

326

Q93097
CNKCGKSCSQMAHLV

ZNF606

626

Q8WXB4