Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

3.78e-12371429GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24

4.93e-12381429GO:0070001
GeneOntologyMolecularFunctionzinc ion binding

ERVK-6 PRICKLE4 TRIM51 TRIM75 MARCHF8 SEC24A TUT1 ERVK-7 ERVK-21 CPM ERVK-9 ZRANB3 BRAP TRIM67 P2RX4 ERVK-8 ADAMTS20 ERVK-19 ERVK-24 RABGGTA TOP3A

1.35e-0689114221GO:0008270
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-8

5.57e-05111423GO:0004523
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPM4 TRPM2 P2RX4 TRPM8

6.64e-05311424GO:0099604
GeneOntologyMolecularFunctionpeptidase activity

USP50 ERVK-6 USP18 ERVK-7 ERVK-21 CPM ERVK-9 ERVK-8 ERVK-18 PAN2 SENP6 ADAMTS20 ERVK-19 ERVK-25 ERVK-24

6.68e-0565414215GO:0008233
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-6 PRICKLE4 TRIM51 TRIM75 MARCHF8 SEC24A TUT1 ERVK-7 ERVK-21 CPM ERVK-9 ZRANB3 BRAP TRIM67 P2RX4 ERVK-8 ADAMTS20 ERVK-19 ERVK-24 RABGGTA TOP3A

1.02e-04118914221GO:0046914
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-8

1.21e-04141423GO:0003964
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 SENP6 ADAMTS20 ERVK-19 ERVK-25 ERVK-24

2.59e-0443014211GO:0004175
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-8

4.26e-04211423GO:0035613
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TRPM4 TRPM2 CHRNA7 P2RX4 TRPM8 CHRFAM7A

5.00e-041401426GO:0099094
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RMND5B AMFR TRIM51 TRIM75 MARCHF8 RNF135 FBXO17 BRAP ZNF451 RNF133

5.69e-0439814210GO:0061659
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RMND5B AMFR TRIM51 TRIM75 MARCHF8 RNF135 FBXO17 BRAP ZNF451 OBI1 RNF133

1.10e-0351214211GO:0019787
GeneOntologyMolecularFunctionacyltransferase activity

RMND5B AMFR TRIM51 TRIM75 MARCHF8 RNF135 ZDHHC7 FBXO17 BRAP BAZ1A ZNF451 HHAT OBI1 RNF133

1.27e-0377514214GO:0016746
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 PNKP ERVK-7 PNLDC1 ZRANB3 ERVK-8 PAN2

1.34e-032311427GO:0004518
GeneOntologyMolecularFunctionubiquitin protein ligase activity

RMND5B AMFR TRIM51 TRIM75 MARCHF8 RNF135 FBXO17 BRAP RNF133

1.40e-033721429GO:0061630
GeneOntologyMolecularFunctionaminoacyltransferase activity

RMND5B AMFR TRIM51 TRIM75 MARCHF8 RNF135 FBXO17 BRAP ZNF451 OBI1 RNF133

1.50e-0353214211GO:0016755
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 CD53 ERVK-19

2.90e-05851446GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 CD53 ERVK-19

2.90e-05851446GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 ERVK-21 ERVK-9 ERVK-8 CD53 ERVK-19

3.76e-05891446GO:0006949
GeneOntologyBiologicalProcesspositive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

CHRNA7 CHRFAM7A

4.84e-0521442GO:0001988
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

USP50 FNIP2 MKKS VLDLR RAP1A SYNE1 WNT5A SPTBN2 TRPM2 LRRTM3 CYFIP2 SPTBN5 LIMK2 CYFIP1 P2RX4 MTMR3 PAN2 SENP6 CCN2 CCR7 TBCD

7.98e-05118914421GO:0044087
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-8

9.05e-05131443GO:0015074
GeneOntologyBiologicalProcesspositive regulation of amide metabolic process

LRRTM3 CHRNA7 TNFRSF1A CHRFAM7A

1.26e-04371444GO:0034250
GeneOntologyBiologicalProcessneuron projection arborization

WNT5A CHRNA7 LRP2 CHRFAM7A

1.40e-04381444GO:0140058
GeneOntologyBiologicalProcessbaroreceptor response to decreased systemic arterial blood pressure

CHRNA7 CHRFAM7A

1.45e-0431442GO:0001982
GeneOntologyBiologicalProcessregulation of organelle organization

MKKS PNKP DRD3 MAP6 EML4 SYNE1 WNT5A SPTBN2 TRPM2 CYFIP2 SPTBN5 FZR1 LIMK2 CYFIP1 BUB1B MTMR3 PAN2 SENP6 CCN2 CCR7 TBCD TECPR1

1.56e-04134214422GO:0033043
GeneOntologyCellularComponentvacuolar membrane

FNIP2 VLDLR MARCHF8 TRPM2 RRAGB VAC14 SLCO4C1 P2RX4 CSF3R LRP2 WDFY3 TECPR1 SEC13

5.82e-0550714613GO:0005774
GeneOntologyCellularComponentspine apparatus membrane

CHRNA7 CHRFAM7A

1.45e-0431462GO:0098897
GeneOntologyCellularComponentubiquitin ligase complex

RMND5B AMFR PNKP FBXO17 SKP2 BRAP FZR1 FBXO8 BUB1B MKLN1

1.88e-0435214610GO:0000151
GeneOntologyCellularComponentlysosomal membrane

FNIP2 VLDLR MARCHF8 TRPM2 RRAGB SLCO4C1 P2RX4 CSF3R LRP2 TECPR1 SEC13

4.11e-0446214611GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

FNIP2 VLDLR MARCHF8 TRPM2 RRAGB SLCO4C1 P2RX4 CSF3R LRP2 TECPR1 SEC13

4.11e-0446214611GO:0098852
MousePhenoairway basal cell hyperplasia

CHRNA7 CHRFAM7A

5.59e-0521052MP:0011115
MousePhenoabnormal airway basal cell differentiation

CHRNA7 CHRFAM7A

5.59e-0521052MP:0011114
MousePhenoabnormal airway basal cell morphology

CHRNA7 CHRFAM7A

5.59e-0521052MP:0011113
DomainTLV_coat

ERVV-2 ERVMER34-1 ERVV-1

1.35e-0571383PF00429
DomainTLV/ENV_coat_polyprotein

ERVV-2 ERVMER34-1 ERVV-1

2.15e-0581383IPR018154
Domain-

RMND5B AMFR TRIM51 MTF2 MARCHF8 RNF135 BRAP TRIM67 BAZ1A MTMR3 WDFY3 OBI1 RNF133

2.91e-05449138133.30.40.10
DomainZnf_RING/FYVE/PHD

RMND5B AMFR TRIM51 MTF2 MARCHF8 RNF135 BRAP TRIM67 BAZ1A MTMR3 WDFY3 OBI1 RNF133

3.66e-0545913813IPR013083
DomainCytoplasmic_FMR1-int

CYFIP2 CYFIP1

5.42e-0521382IPR008081
DomainFragX_IP

CYFIP2 CYFIP1

5.42e-0521382PF05994
DomainWD40_repeat_dom

WDR4 EML4 FZR1 AAAS WDR97 STRN4 PAN2 WDR86 WDFY3 SEC13

7.32e-0529713810IPR017986
DomainWD40

WDR4 EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3 SEC13

1.34e-042591389PF00400
DomainGlyco_hormone_CN

MUC5B CCN4 CCN2

1.68e-04151383IPR006208
DomainCys_knot

MUC5B CCN4 CCN2

1.68e-04151383PF00007
DomainWD40

WDR4 EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3 SEC13

1.73e-042681389SM00320
Domain-

WDR4 EML4 FZR1 AAAS WDR97 STRN4 PAN2 WDR86 WDFY3 SEC13

1.87e-04333138102.130.10.10
DomainWD40_repeat

WDR4 EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3 SEC13

1.93e-042721389IPR001680
DomainWD40/YVTN_repeat-like_dom

WDR4 EML4 FZR1 AAAS WDR97 STRN4 PAN2 WDR86 WDFY3 SEC13

1.96e-0433513810IPR015943
DomainLDLR_class-A_CS

VLDLR MAMDC4 MALRD1 LRP2

2.12e-04401384IPR023415
DomainWD40_repeat_CS

EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3

2.19e-041641387IPR019775
DomainWD_REPEATS_1

WDR4 EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3 SEC13

2.27e-042781389PS00678
DomainWD_REPEATS_2

WDR4 EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3 SEC13

2.33e-042791389PS50082
DomainWD_REPEATS_REGION

WDR4 EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3 SEC13

2.33e-042791389PS50294
Domainzf-C3HC4

AMFR TRIM51 MARCHF8 RNF135 BRAP TRIM67 OBI1 RNF133

2.56e-042231388PF00097
DomainZnf_C3HC4_RING-type

AMFR TRIM51 MARCHF8 RNF135 BRAP TRIM67 RNF133

2.93e-041721387IPR018957
DomainCTCK_1

MUC5B CCN4 CCN2

2.97e-04181383PS01185
DomainDUF1394

CYFIP2 CYFIP1

3.22e-0441382IPR009828
DomainDUF1394

CYFIP2 CYFIP1

3.22e-0441382PF07159
DomainLdl_recept_a

VLDLR MAMDC4 MALRD1 LRP2

3.36e-04451384PF00057
Domain-

VLDLR MAMDC4 MALRD1 LRP2

3.66e-044613844.10.400.10
DomainLDLRA_1

VLDLR MAMDC4 MALRD1 LRP2

4.31e-04481384PS01209
DomainLDrepeatLR_classA_rpt

VLDLR MAMDC4 MALRD1 LRP2

4.67e-04491384IPR002172
DomainLDLa

VLDLR MAMDC4 MALRD1 LRP2

4.67e-04491384SM00192
DomainLDLRA_2

VLDLR MAMDC4 MALRD1 LRP2

4.67e-04491384PS50068
DomainIGFBP_CNN

CCN4 CCN2

5.34e-0451382IPR012395
DomainCT

MUC5B CCN4 CCN2

5.48e-04221383SM00041
DomainSpectrin

SYNE1 SPTBN2 SPTBN5

6.27e-04231383PF00435
DomainACTININ_2

SYNE1 SPTBN2 SPTBN5

6.27e-04231383PS00020
DomainACTININ_1

SYNE1 SPTBN2 SPTBN5

6.27e-04231383PS00019
DomainActinin_actin-bd_CS

SYNE1 SPTBN2 SPTBN5

6.27e-04231383IPR001589
DomainZnf_RING

AMFR TRIM51 MARCHF8 RNF135 BRAP TRIM67 BAZ1A OBI1 RNF133

7.20e-043261389IPR001841
DomainCys_knot_C

MUC5B CCN4 CCN2

8.06e-04251383IPR006207
DomainCTCK_2

MUC5B CCN4 CCN2

8.06e-04251383PS01225
DomainVWC

MUC5B CCN4 CCN2

1.13e-03281383PF00093
DomainSpectrin_repeat

SYNE1 SPTBN2 SPTBN5

1.25e-03291383IPR002017
DomainSPEC

SYNE1 SPTBN2 SPTBN5

1.67e-03321383SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTBN2 SPTBN5

1.67e-03321383IPR018159
DomainPH_dom-spectrin-type

SPTBN2 SPTBN5

1.89e-0391382IPR001605
DomainRING

AMFR TRIM51 RNF135 BRAP TRIM67 BAZ1A OBI1 RNF133

1.96e-033051388SM00184
DomainCTLH_C

RMND5B MKLN1

2.35e-03101382IPR006595
DomainRap_GAP

SIPA1 SIPA1L2

2.35e-03101382PF02145
DomainCTLH

RMND5B MKLN1

2.35e-03101382PS50897
DomainVWFC_1

MUC5B CCN4 CCN2

2.36e-03361383PS01208
DomainVWFC_2

MUC5B CCN4 CCN2

2.76e-03381383PS50184
DomainVWC

MUC5B CCN4 CCN2

2.76e-03381383SM00214
DomainRap_GAP_dom

SIPA1 SIPA1L2

2.85e-03111382IPR000331
DomainInsulin_GF-bd_Cys-rich_CS

CCN4 CCN2

2.85e-03111382IPR017891
DomainRAPGAP

SIPA1 SIPA1L2

2.85e-03111382PS50085
DomainIGFBP_N_1

CCN4 CCN2

3.41e-03121382PS00222
DomainVWF_dom

MUC5B CCN4 CCN2

3.67e-03421383IPR001007
DomainF-box-like

FBXO17 SKP2 FBXO8

4.19e-03441383PF12937
DomainTIL_dom

MUC5B LRP2

4.65e-03141382IPR002919
DomainLdl_recept_b

VLDLR LRP2

4.65e-03141382PF00058
DomainLDLRB

VLDLR LRP2

4.65e-03141382PS51120
DomainLY

VLDLR LRP2

5.34e-03151382SM00135
DomainN2O_reductase_N

FZR1 AAAS

5.34e-03151382IPR011045
DomainLDLR_classB_rpt

VLDLR LRP2

5.34e-03151382IPR000033
DomainConA-like_dom

TRIM51 RNF135 MAMDC4 MALRD1 TRIM67 WDFY3

5.79e-032191386IPR013320
DomainZF_RING_1

AMFR TRIM51 RNF135 BRAP TRIM67 OBI1 RNF133

5.94e-032911387PS00518
Domainzf-RING_2

AMFR BRAP RNF133

6.70e-03521383PF13639
DomainZF_RING_2

AMFR TRIM51 RNF135 BRAP TRIM67 OBI1 RNF133

6.74e-032981387PS50089
DomainMAM

MAMDC4 MALRD1

6.85e-03171382SM00137
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVV-2 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 ERVK-19 ERVV-1 ERVK-25 ERVK-24

2.90e-13941481121542922
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-18 ERVK-19

1.30e-125148512629516
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

1.01e-0912148514557543
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-18 ERVK-25 ERVK-24

1.07e-0818148518664271
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18 ERVK-19

7.55e-083148310516026
Pubmed

Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair.

CHRNA7 TLR5 TNFRSF1A CHRFAM7A

1.02e-0711148432908007
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-24

3.01e-074148310469592
Pubmed

Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.

ERVK-6 ERVV-2 ERVV-1

1.50e-066148323085571
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

1.50e-066148315063128
Pubmed

Syncytins expressed in human placental trophoblast.

ERVV-2 ERVMER34-1 ERVV-1

4.16e-068148333504453
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19

8.87e-0610148312970426
Pubmed

Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.

TRPM4 TRPM2 TRPM8

1.62e-0512148319850157
Pubmed

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.

USP50 USP18 PAN2

1.62e-0512148327801882
Pubmed

Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.

CHRNA7 CHRFAM7A

1.80e-052148238070724
Pubmed

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.

CHRNA7 CHRFAM7A

1.80e-052148234453977
Pubmed

Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

CHRNA7 CHRFAM7A

1.80e-052148226999808
Pubmed

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.

CHRNA7 CHRFAM7A

1.80e-052148227129924
Pubmed

Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.

CHRNA7 CHRFAM7A

1.80e-052148223521765
Pubmed

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.

CHRNA7 CHRFAM7A

1.80e-052148228258105
Pubmed

The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.

CHRNA7 CHRFAM7A

1.80e-052148219344760
Pubmed

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.

CHRNA7 CHRFAM7A

1.80e-052148229114104
Pubmed

Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.

CHRNA7 CHRFAM7A

1.80e-052148233995108
Pubmed

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.

CHRNA7 CHRFAM7A

1.80e-052148232552811
Pubmed

Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.

CHRNA7 CHRFAM7A

1.80e-052148224836856
Pubmed

Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.

CHRNA7 CHRFAM7A

1.80e-052148215948184
Pubmed

Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.

CHRNA7 CHRFAM7A

1.80e-052148235678315
Pubmed

Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.

CHRNA7 CHRFAM7A

1.80e-052148212628457
Pubmed

Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.

CHRNA7 CHRFAM7A

1.80e-052148225157794
Pubmed

Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.

CHRNA7 CHRFAM7A

1.80e-052148231202708
Pubmed

Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.

CHRNA7 CHRFAM7A

1.80e-052148222246862
Pubmed

Importance of a conserved sequence motif in transmembrane segment S3 for the gating of human TRPM8 and TRPM2.

TRPM2 TRPM8

1.80e-052148223185472
Pubmed

Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.

CHRNA7 CHRFAM7A

1.80e-052148227471776
Pubmed

Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.

CYFIP2 CYFIP1

1.80e-052148238128786
Pubmed

Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.

CHRNA7 CHRFAM7A

1.80e-052148222688057
Pubmed

[Expression of G-CSF and GM-CSF receptors on CD34 positive cells in aplastic anemia and myelodysplastic syndrome patients and its significance].

CSF2RA CSF3R

1.80e-052148219099633
Pubmed

Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.

CHRNA7 CHRFAM7A

1.80e-052148232028688
Pubmed

Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.

CHRNA7 CHRFAM7A

1.80e-052148230429582
Pubmed

A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.

CHRNA7 CHRFAM7A

1.80e-052148221501254
Pubmed

Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.

CHRNA7 CHRFAM7A

1.80e-052148221368056
Pubmed

Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.

CHRNA7 CHRFAM7A

1.80e-05214821400473
Pubmed

Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.

CHRNA7 CHRFAM7A

1.80e-052148226937017
Pubmed

Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.

CHRNA7 CHRFAM7A

1.80e-052148236603528
Pubmed

Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.

CHRNA7 CHRFAM7A

1.80e-052148226650489
Pubmed

Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.

CHRNA7 CHRFAM7A

1.80e-052148222848433
Pubmed

Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.

CHRNA7 CHRFAM7A

1.80e-052148216650968
Pubmed

Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.

CHRNA7 CHRFAM7A

1.80e-052148235413868
Pubmed

Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.

CHRNA7 CHRFAM7A

1.80e-052148224462939
Pubmed

Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.

CHRNA7 CHRFAM7A

1.80e-052148229261717
Pubmed

Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.

CHRNA7 CHRFAM7A

1.80e-052148218199426
Pubmed

Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.

CHRNA7 CHRFAM7A

1.80e-052148222490926
Pubmed

Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.

CHRNA7 CHRFAM7A

1.80e-052148223270857
Pubmed

Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.

CHRNA7 CHRFAM7A

1.80e-052148218077004
Pubmed

Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.

SKP2 FZR1

1.80e-052148221212736
Pubmed

Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.

CHRNA7 CHRFAM7A

1.80e-052148219462340
Pubmed

Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.

CHRNA7 CHRFAM7A

1.80e-052148216923147
Pubmed

NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

1.80e-052148211790782
Pubmed

Cdh1-anaphase-promoting complex targets Skp2 for destruction in transforming growth factor beta-induced growth inhibition.

SKP2 FZR1

1.80e-052148217283060
Pubmed

Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.

CHRNA7 CHRFAM7A

1.80e-052148237746145
Pubmed

A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

CHRNA7 CHRFAM7A

1.80e-052148219631623
Pubmed

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

CHRNA7 CHRFAM7A

1.80e-052148215770102
Pubmed

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.

CHRNA7 CHRFAM7A

1.80e-052148224326163
Pubmed

Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.

TRPM2 TRPM8

1.80e-052148220587417
Pubmed

Dissection of the APCCdh1-Skp2 cascade in breast cancer.

SKP2 FZR1

1.80e-052148218381934
Pubmed

Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.

CHRNA7 CHRFAM7A

1.80e-052148223811428
Pubmed

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.

ERVV-2 ERVV-1

1.80e-052148218826608
Pubmed

Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.

CHRNA7 CHRFAM7A

1.80e-052148220720594
Pubmed

Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.

CHRNA7 CHRFAM7A

1.80e-052148217019565
Pubmed

Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.

CHRNA7 CHRFAM7A

1.80e-052148219100751
Pubmed

Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.

CHRNA7 CHRFAM7A

1.80e-052148235883638
Pubmed

Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.

CHRNA7 CHRFAM7A

1.80e-052148219368846
Pubmed

Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones.

CHRNA7 CHRFAM7A

1.80e-052148215009674
Pubmed

Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression.

CHRNA7 CHRFAM7A

1.80e-052148238253622
Pubmed

The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.

CHRNA7 CHRFAM7A

1.80e-052148234514543
Pubmed

α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.

CHRNA7 CHRFAM7A

1.80e-052148222183893
Pubmed

Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents.

CHRNA7 CHRFAM7A

1.80e-05214829364063
Pubmed

Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

1.80e-052148212606407
Pubmed

Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia.

CHRNA7 CHRFAM7A

1.80e-052148222300029
Pubmed

GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice.

CHRNA7 CHRFAM7A

1.80e-052148232018068
Pubmed

CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders.

CHRNA7 CHRFAM7A

1.80e-052148226206074
Pubmed

Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.

CHRNA7 CHRFAM7A

1.80e-052148224349346
Pubmed

The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.

CHRNA7 CHRFAM7A

1.80e-052148221143250
Pubmed

Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.

CHRNA7 CHRFAM7A

1.80e-052148216319313
Pubmed

Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.

CHRNA7 CHRFAM7A

1.80e-052148225797465
Pubmed

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.

CHRNA7 CHRFAM7A

1.80e-052148229197398
Pubmed

Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.

CHRNA7 CHRFAM7A

1.80e-052148238178134
Pubmed

In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.

CHRNA7 CHRFAM7A

1.80e-052148223325242
Pubmed

Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.

CHRNA7 CHRFAM7A

1.80e-052148222649244
Pubmed

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.

CHRNA7 CHRFAM7A

1.80e-052148217898229
Pubmed

Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.

CHRNA7 CHRFAM7A

1.80e-052148221901321
Pubmed

Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors.

CHRNA7 CHRFAM7A

1.80e-052148217935702
Pubmed

Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.

CHRNA7 CHRFAM7A

1.80e-052148220624304
Pubmed

Cytokine-induced alterations of α7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis.

CHRNA7 CHRFAM7A

1.80e-052148221784975
Pubmed

Lack of acetylcholine nicotine alpha 7 receptor suppresses development of collagen-induced arthritis and adaptive immunity.

CHRNA7 CHRFAM7A

1.80e-052148220659128
Pubmed

Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.

CHRNA7 CHRFAM7A

1.80e-052148220843956
Pubmed

Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth.

CHRNA7 CHRFAM7A

1.80e-052148210800961
Pubmed

Characterization of allelic variants at chromosome 15q14 in schizophrenia.

CHRNA7 CHRFAM7A

1.80e-052148216417613
Pubmed

Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.

CHRNA7 CHRFAM7A

1.80e-052148211834293
Pubmed

Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.

CHRNA7 CHRFAM7A

1.80e-052148222314319
Pubmed

Antagonism of Cerebral High Mobility Group Box 1 Ameliorates Dendritic Cell Dysfunction in Sepsis.

CHRNA7 CHRFAM7A

1.80e-052148234512319
Pubmed

Visual acuity is reduced in alpha 7 nicotinic receptor knockout mice.

CHRNA7 CHRFAM7A

1.80e-052148222281823
GeneFamilyWD repeat domain containing

WDR4 EML4 FZR1 AAAS WDR97 STRN4 WDR86 WDFY3 SEC13

1.36e-05262999362
GeneFamilyRing finger proteins

AMFR TRIM51 TRIM75 MARCHF8 RNF135 BRAP TRIM67 OBI1 RNF133

2.00e-0527599958
GeneFamilyCYR61/CTGF/NOV matricellular proteins

CCN4 CCN2

4.39e-0469921046
GeneFamilyTransient receptor potential cation channels

TRPM4 TRPM2 TRPM8

4.72e-0428993249
GeneFamilyEF-hand domain containing|Spectrins

SPTBN2 SPTBN5

6.12e-0479921113
GeneFamilyLow density lipoprotein receptors

VLDLR LRP2

2.23e-0313992634
GeneFamilyUbiquitin specific peptidases

USP50 USP18 PAN2

3.58e-0356993366
CoexpressionTRAVAGLINI_LUNG_OLR1_CLASSICAL_MONOCYTE_CELL

FNIP2 MKKS EML4 EMILIN2 CD55 LIMK2 CYFIP1 CSF2RA P2RX4 CSF3R BAZ1A CD53 PCNX1 WDFY3 TNFRSF1A

6.76e-0672413815M41700
CoexpressionGSE1432_1H_VS_6H_IFNG_MICROGLIA_DN

TRPM4 IL32 WNT5A LIMK2 BAZ1A CD53 PCNX1 ARAP2

1.14e-052001388M3411
CoexpressionAtlasmendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K4

USP18 CPM P2RX4 LRP2 CCN2

6.46e-06411375mendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K4
CoexpressionAtlasalpha beta T cells, T.8.Sp.B16, 4- 8+ TCR+ 45+, B16 Melanoma Spleen, avg-3

ADGRG5 CD55 CPM CD6 CCR7

6.77e-05661375GSM605770_100
CoexpressionAtlasalpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1

ADGRG5 CD55 CPM CD6 CCR7

7.28e-05671375GSM538414_100
CoexpressionAtlasCD positive, T.8Nve.Sp.OT1, CD8+ CD45.1+, Spleen, avg-3

ADGRG5 CD55 CPM CD6 CCR7

8.98e-05701375GSM605909_100
CoexpressionAtlasJC_hmvEC_top-relative-expression-ranked_1000_k-means-cluster#4

USP18 PRICKLE4 IL32 CD55 PKHD1L1 SPTBN5 CFAP54 PIEZO2 P2RX4 CCN2 TECPR1

1.07e-0442813711JC_hmvEC_1000_K4
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_200

CPM PIEZO2 PDE8B CD53 CCN2 TMEM140 ARAP2

1.07e-041671377gudmap_kidney_adult_Mesangium_Meis_200
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_500

ACER2 USP18 SYNE1 CPM PIEZO2 P2RX4 PDE8B CD53 CCN2 TMEM140 ARAP2

1.09e-0442913711gudmap_kidney_adult_Mesangium_Meis_500
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B PKHD1L1 PIEZO2 PIK3C2G LRP2 ADAMTS20 ZNF488

1.85e-0618413972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B PKHD1L1 PIEZO2 PIK3C2G LRP2 ADAMTS20 ZNF488

1.85e-0618413972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B PKHD1L1 PIEZO2 PIK3C2G LRP2 ADAMTS20 ZNF488

1.85e-061841397ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellPBMC-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

IL32 MAP6 WNT5A CENPI CCN2 CCR7 WDR86

1.92e-0618513974b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACER2 PDE1B SYNE1 CPM CCN4 PIEZO2 WDR86

2.06e-06187139715d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACER2 PDE1B SYNE1 CPM CCN4 PIEZO2 WDR86

2.06e-061871397f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VWA3A MAP6 SYNE1 ARMC2 CFAP54 CCN2 DNAH6

2.72e-0619513973486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-cDC2-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADGRG5 CD55 CSF2RA CD53 ERVV-1 CCR7 CHRFAM7A

2.72e-061951397d11d559a3afcb8ae845edea14d4cfeb41d82e165
ToppCellT_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

IL32 EML4 CYFIP2 CD6 CD53 CCR7 ARAP2

3.00e-0619813978372ceed063acad0e219644ddd58abbd1354e734
ToppCellCOVID-19-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

IL32 FBXO17 PIEZO2 CSF2RA CCR7 CHRFAM7A ARAP2

3.00e-06198139790f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

USP18 IL32 EML4 SYNE1 HELB CD6 CCR7

3.10e-061991397952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 CD55 LIMK2 CSF3R BAZ1A PCNX1 WDFY3

3.21e-0620013976beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLXDC1 SYNE1 CCN4 PDE8B SUSD5 KCNS3 CCN2

3.21e-062001397b22cae282591d8dead9869c2adbb9632615f50f7
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 CD55 LIMK2 CSF3R BAZ1A PCNX1 WDFY3

3.21e-062001397026495aa7f1e7528a01d9199475cfc393677fc60
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PNLDC1 SPTBN5 CD6 STC2 CCR7

3.55e-0674139508874e430b4c9fcb2c1758c4178cb0c45671b125
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 TRPM2 CYFIP2 CSF2RA CSF3R CD53

7.45e-061491396c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 TRPM2 CYFIP2 CSF2RA CSF3R CD53

7.45e-0614913964de52569611e63a780cde9bd111d6d9c11a05a11
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VWA3A ARMC2 ERVMER34-1 CFAP20DC BUB1B DNAH6

7.74e-0615013969cb3332924bd67c966873343c14445e30d3f384f
ToppCellfacs-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 TRPM2 CSF2RA CSF3R TNFRSF1A DNAH6

9.69e-061561396034d4359359a44c205c6931f38a375271ac2752b
ToppCellfacs-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 TRPM2 CSF2RA CSF3R TNFRSF1A DNAH6

9.69e-06156139621267718d3a3dc19988663b6846aed8bb3eae836
ToppCellfacs-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 EMILIN2 SLCO4C1 CSF3R TLR5 TNFRSF1A

9.69e-061561396f1e25ff85c5f2f8555f9fb5ae5daed7ddb418fd1
ToppCellfacs-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 TRPM2 CSF2RA CSF3R TNFRSF1A DNAH6

9.69e-0615613962a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCellfacs-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 EMILIN2 SLCO4C1 CSF3R TLR5 TNFRSF1A

9.69e-061561396f532ef4e92ac7661b1a8a4f2e98d80ce8d4e3655
ToppCellfacs-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 EMILIN2 SLCO4C1 CSF3R TLR5 TNFRSF1A

9.69e-061561396da4f35353a84d919e683554932f110e29568df33
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ACER2 PLXDC1 GRB7 P2RX4 SUSD5 RASL11B

1.04e-051581396c8af8964a140acb2987e3b4906d72c546108d229
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A MUC5B PKHD1L1 PIK3C2G LRP2 TRPM8

1.12e-051601396c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A MUC5B PKHD1L1 PIK3C2G LRP2 TRPM8

1.12e-05160139625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-CD8_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IL32 PLXDC1 PLEKHG4 GPR52 CD6 CCR7

1.80e-051741396fee2ee3e888ce71f9f3f05d7dc8aaa9549480205
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 IL32 SYNE1 CD6 SLCO4C1 PDE8B

1.92e-0517613965914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL32 SEC24A SENP6 ZNF75A GATD1 WDR86

2.11e-0517913966bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWA3A SYNE1 CFAP54 CCN2 NRG3 SIPA1L2

2.25e-0518113965f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWA3A SYNE1 CFAP54 CCN2 NRG3 SIPA1L2

2.25e-051811396c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VWA3A SYNE1 CFAP54 CCN2 NRG3 SIPA1L2

2.54e-0518513968816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VWA3A SYNE1 CFAP54 CCN2 NRG3 SIPA1L2

2.54e-05185139634fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD55 CPM CYFIP2 CD53 CCR7 ARAP2

2.62e-051861396d5d990d8b6ccd8ca8fe7d0d7dedbe2359ae7b582
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

ADGRG5 CYFIP2 HELB CD6 CD53 PCNX1

2.70e-051871396f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACER2 SYNE1 CPM CCN4 PIEZO2 WDR86

2.78e-05188139632f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1A CD6 CD53 CCR7 ARAP2 TECPR1

2.95e-051901396d85b34d19af43d83ebe728f3c7bbefd3792df4a6
ToppCellT_cells-Effector_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

IL32 PLXDC1 EML4 CD6 PCNX1 WDR86

2.95e-05190139613dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

EML4 CYFIP2 HELB CD6 CD53 PCNX1

2.95e-0519013960733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1B PLXDC1 MUC5B CPM PDE8B ARAP2

2.95e-0519013961ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCellCOVID-19-lung-CD4+_Treg|lung / Disease (COVID-19 only), tissue and cell type

EML4 CYFIP2 HELB CD6 CD53 CCR7

3.04e-05191139673ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1B PLXDC1 CPM PDE8B WDR86 ARAP2

3.04e-051911396a7494191a92984e5f53610bbbedd6714e9169e1c
ToppCellfacs-Heart-LA-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1B PLXDC1 CPM PDE8B WDR86 ARAP2

3.04e-0519113969c5d88f0d3c834c2419ec3da74652175153ba9df
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

TRPM2 CPM CSF2RA CSF3R CD53 ARAP2

3.13e-0519213967be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCelltumor_Lung-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

ADGRG5 TRPM2 CD6 CSF2RA CD53 CCR7

3.22e-0519313968cc7172c327a9cf6823e1a35322a4e5960826ec8
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

TRPM2 CPM CSF2RA CSF3R BUB1B CD53

3.22e-05193139612bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

CD55 CPM CSF2RA CSF3R CD53 PCNX1

3.22e-0519313965fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellCOVID-19-kidney-T-cells-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

EML4 CYFIP2 HELB CD6 CD53 ARAP2

3.22e-0519313965b84fa640cf30dea55fde53b810f850ff946d253
ToppCellCOVID-19-Heart-Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

TRPM2 EMILIN2 CPM CSF2RA CSF3R CD53

3.32e-051941396f09675cd472200363c458952f00d2e41990800ee
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

TRPM2 EMILIN2 CPM CSF2RA CD53 ARAP2

3.32e-051941396c1805572bcc11b1cd29083329d7b5911489fb758
ToppCelldistal-Hematologic-Myeloid_Dendritic_Type_1-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ZDHHC7 CHRNA7 CSF2RA CCR7 LBHD1 ARAP2

3.32e-051941396f0467d81063a9b19783906c456935ef8318b9b98
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

TRPM2 EMILIN2 CPM CSF2RA CD53 ARAP2

3.42e-0519513965e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

ADGRG5 IL32 SYNE1 CYFIP2 PCNX1 ARAP2

3.42e-0519513969990440bda7fac5d00ef80444fab07459be625e1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-cDC2|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRPM4 ERVV-2 CD55 SLCO4C1 CD53 CCR7

3.42e-0519513969c6bed8414633813e1655bbeaab682fb296958a9
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL32 CYFIP2 CD6 CD53 CCR7 ARAP2

3.42e-0519513968687b319f1f487fbef4ca075fad054751a641de6
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FNIP2 TRPM2 EMILIN2 CPM CSF2RA CD53

3.42e-051951396ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 EMILIN2 CD6 CSF2RA CSF3R CD53

3.42e-0519513967b6c69df943842b566a596e30bb50dbe80dccc83
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADGRG5 IL32 SYNE1 CYFIP2 PCNX1 ARAP2

3.52e-051961396418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADGRG5 IL32 SYNE1 CYFIP2 PCNX1 ARAP2

3.52e-051961396581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 IL32 SYNE1 CYFIP2 CD6 ARAP2

3.52e-05196139651c750a0fb2b87e17e62b984c91fb16f676d7e76
ToppCellT_cells-GZMK+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

IL32 EML4 CYFIP2 CD6 CD53 ARAP2

3.52e-051961396fa5c7fec9e0dcd7e62ff64704bfdf2a3437a43ba
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADGRG5 IL32 SYNE1 CYFIP2 PCNX1 ARAP2

3.52e-0519613966beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADGRG5 IL32 SYNE1 CYFIP2 PCNX1 ARAP2

3.52e-051961396c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

VWA3A TCTE1 SYNE1 CFAP54 KNDC1 DNAH6

3.62e-051971396fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL32 EML4 HELB CD6 CD53 CCR7

3.62e-051971396e60deb009238702110c3b0948778802df215ad74
ToppCellT_cells-CCR7+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

IL32 EML4 CYFIP2 CD6 CD53 CCR7

3.62e-051971396904430779c42b51d3eec62cf0cdd501b17058d8b
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP18 IL32 SYNE1 HELB CD6 CCR7

3.62e-0519713960b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCellBAL-Mild-cDC_10|Mild / Compartment, Disease Groups and Clusters

IL32 VAC14 CSF2RA CCR7 CHRFAM7A ARAP2

3.62e-051971396c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WNT5A CPM CYFIP1 CSF2RA CSF3R CD53

3.62e-05197139650f994e0d4e69019ec92e164edf3e4e951333766
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP18 IL32 SYNE1 HELB CD6 CCR7

3.62e-051971396b3876076684781fb8384117f2cf367d828985986
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-MAIT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ACER2 IL32 EML4 CD6 CD53 CCR7

3.72e-051981396f26150ae3fee6b2df2a51efaefbcfeb27f725a65
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRG5 TRPM2 EMILIN2 CSF2RA CENPI BUB1B

3.72e-051981396732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM2 EMILIN2 SIPA1 CSF2RA CSF3R CD53

3.83e-051991396744b63fba33b176ab7dde11646ccb313665505f7
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNIP2 SYNE1 CPM SLCO4C1 CSF3R LRP2

3.83e-0519913962dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM2 EMILIN2 CPM SIPA1 CSF2RA CSF3R

3.83e-051991396b818d46a39c8782188d82dc8931b8eec9d549dd1
ToppCellSepsis-ICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, condition lineage and cell class

TRPM4 VLDLR CSF2RA PDE8B HHAT SEC13

3.83e-05199139690ddd686b8f39c6f6134b9b048396cebcf8d0448
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM2 EMILIN2 CPM SIPA1 CSF2RA CSF3R

3.83e-05199139698c0d57c247d39bc771d81f4387f8dd01222628e
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IL32 EML4 CYFIP2 HELB CD6 CD53

3.83e-0519913965a29db2610ba06a2248325a16cad755d20debf2c
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM2 RNF135 EMILIN2 CPM CSF2RA CSF3R

3.83e-0519913969545ac59c8d75f5747dff86cb511a149dc103b31
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 CD55 SLCO4C1 CSF3R BAZ1A WDFY3

3.83e-051991396b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM2 EMILIN2 CPM CSF2RA CSF3R CD53

3.93e-052001396700960201ae0df2c79e2907f5a0f95d73f8034fe
ToppCellTracheal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM2 EMILIN2 CPM CSF2RA CSF3R CD53

3.93e-052001396ad7ae5106141669b353800fece833b3cd5bdccee
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM2 EMILIN2 CPM CSF2RA CSF3R CD53

3.93e-052001396f3dc07a7cc8cf041da8fe610d21af595818cf2d8
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PLXDC1 CCN4 SLCO4C1 PDE8B SUSD5 KCNS3

3.93e-052001396b5b5a32925f225610fe25a021a742d6397162863
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WNT5A MUC5B CHRNA7 LIMK2 PIK3C2G WDR86

3.93e-052001396b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PLXDC1 CCN4 SLCO4C1 PDE8B KCNS3 WDR86

3.93e-052001396d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 CFAP54 PIEZO2 STC2 SUSD5 CCN2

3.93e-052001396f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PLXDC1 CCN4 SLCO4C1 PDE8B KCNS3 WDR86

3.93e-052001396786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 CD55 SLCO4C1 CSF3R BAZ1A WDFY3

3.93e-052001396808571d74bb5c4d765ff13fc9393f88020d4e90d
ToppCellBronchus_Control_(B.)-Immune-TX-DCs|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FNIP2 ADGRG5 TRPM2 EMILIN2 CSF2RA CD53

3.93e-052001396e0beacb88bbdc353a3e883171613027feafcf1ef
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

PLXDC1 CCN4 SLCO4C1 PDE8B KCNS3 WDR86

3.93e-052001396bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 CFAP54 PIEZO2 STC2 SUSD5 CCN2

3.93e-052001396b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLXDC1 CCN4 PDE8B KCNS3 CCN2 WDR86

3.93e-052001396cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_3|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

GRB7 MALRD1 CD6 STC2 ARAP2

6.81e-0513613955e209185b5f6e9347829fc9066f0b2c3711df057
ToppCellP03-Hematopoietic|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRG5 EMILIN2 SLC9A4 CD53 CCR7

8.08e-0514113954a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPTBN2 TUT1 CFAP54 RASL11B DNAH6

8.64e-051431395cc396b81a5e47d78c2d1cb49d682391376b63476
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRG5 TRIM67 CD53 TRPM8 ARAP2

1.02e-041481395003e10bf477984248211b99d75daa8f7dcdb12c8
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRG5 EMILIN2 SLC9A4 CD53 CCR7

1.05e-04149139543d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRG5 EMILIN2 SLC9A4 CD53 CCR7

1.05e-0414913951c5a2572741c47246d455c865e8e1677c9f49598
DiseaseSchizophrenia

VLDLR DRD3 MAP6 SPTBN2 CHRNA7 BRAP CYFIP1 CSF2RA HHAT ERVK-8 LRP2 KCNS3 TNFRSF1A NRG3 CHRFAM7A

1.12e-0588313315C0036341
Diseasenicotine dependence (implicated_via_orthology)

DRD3 CHRNA7 CHRFAM7A

1.91e-05121333DOID:0050742 (implicated_via_orthology)
Diseasechromosome 15q11.2 deletion syndrome (implicated_via_orthology)

CYFIP2 CYFIP1

6.03e-0531332DOID:0060393 (implicated_via_orthology)
Diseaseanorectal malformation

TRPM2 MUC5B SUSD5

8.23e-05191333MONDO_0019938
Diseaseirritable bowel syndrome symptom measurement

TRPM2 CHRNA7 TRIM67 CHRFAM7A

1.39e-04581334EFO_0021536
Disease3-dehydrocarnitine measurement

MARCHF8 CSF3R

2.00e-0451332EFO_0021037
Diseaseschizophrenia (implicated_via_orthology)

MAP6 CHRNA7 NRG3 CHRFAM7A

2.57e-04681334DOID:5419 (implicated_via_orthology)
Diseasecognitive disorder (implicated_via_orthology)

CHRNA7 CHRFAM7A

2.99e-0461332DOID:1561 (implicated_via_orthology)
Diseaserheumatoid arthritis (biomarker_via_orthology)

CHRNA7 CHRFAM7A

2.99e-0461332DOID:7148 (biomarker_via_orthology)
DiseaseChild Development Disorders, Specific

PNKP LRP2 TBCD

3.00e-04291333C0085997
DiseaseChild Development Deviations

PNKP LRP2 TBCD

3.00e-04291333C0085996
DiseaseDevelopmental Disabilities

PNKP LRP2 TBCD

3.32e-04301333C0008073
DiseaseSevere Congenital Microcephaly

PNKP BUB1B TBCD

3.67e-04311333C3853041
DiseaseMicrolissencephaly

PNKP BUB1B TBCD

4.42e-04331333C1956147
DiseaseGeneralized seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0234533
DiseaseClonic Seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0234535
DiseaseConvulsive Seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0751494
DiseaseSeizures, Sensory

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0751496
DiseaseNon-epileptic convulsion

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0751056
DiseaseAtonic Absence Seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0751123
DiseaseComplex partial seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0149958
DiseaseSingle Seizure

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0751110
DiseaseNonepileptic Seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C3495874
DiseaseVisual seizure

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0270824
DiseaseEpileptic drop attack

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0270846
DiseaseVertiginous seizure

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0422855
DiseaseGustatory seizure

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0422854
DiseaseSeizures, Somatosensory

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0422850
DiseaseOlfactory seizure

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0422853
DiseaseSeizures, Auditory

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0422852
DiseaseGeneralized Absence Seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C4505436
DiseaseJacksonian Seizure

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C0022333
DiseaseEpileptic Seizures

PNKP DRD3 CHRNA7 TBCD

1.15e-031011334C4317109
DiseaseAbsence Seizures

PNKP DRD3 CHRNA7 TBCD

1.19e-031021334C4316903
DiseaseConvulsions

PNKP DRD3 CHRNA7 TBCD

1.19e-031021334C4048158
DiseaseTonic Seizures

PNKP DRD3 CHRNA7 TBCD

1.19e-031021334C0270844
DiseaseSeizures, Focal

PNKP DRD3 CHRNA7 TBCD

1.28e-031041334C0751495
DiseaseMyoclonic Seizures

PNKP DRD3 CHRNA7 TBCD

1.28e-031041334C4317123
DiseaseTonic - clonic seizures

PNKP DRD3 CHRNA7 TBCD

1.28e-031041334C0494475
DiseaseLenticulostriate Disorders

DRD3 PDE8B

1.29e-03121332C0750951
DiseaseExtrapyramidal Disorders

DRD3 PDE8B

1.29e-03121332C0015371
DiseaseBasal Ganglia Diseases

DRD3 PDE8B

1.29e-03121332C0004782
Diseaseliver cirrhosis (implicated_via_orthology)

FOCAD CCN2

1.52e-03131332DOID:5082 (implicated_via_orthology)
Diseasemale infertility (implicated_via_orthology)

TCTE1 ARMC2

1.52e-03131332DOID:12336 (implicated_via_orthology)
Diseasepuberty onset measurement

PRICKLE4 TRPM2 CYFIP2 MKLN1

2.51e-031251334EFO_0005677
Diseasecystic fibrosis (is_marker_for)

MUC5B CSF3R TLR5

2.79e-03621333DOID:1485 (is_marker_for)
Diseasebehavior or behavioral disorder measurement, personality trait

INTS7 KCNS3

2.94e-03181332EFO_0004365, EFO_0004782
DiseaseUsual Interstitial Pneumonia

WNT5A MUC5B

3.28e-03191332C4721509
DiseaseHamman-Rich Disease

WNT5A MUC5B

3.28e-03191332C4721508
Diseaseperipheral neuropathy, response to docetaxel trihydrate

TRPM2 VAC14

3.28e-03191332EFO_0003100, GO_1902519
DiseaseMicrocephaly

PNKP BUB1B TBCD

3.47e-03671333C0025958
DiseaseFamilial Idiopathic Pulmonary Fibrosis

WNT5A MUC5B

3.63e-03201332C4721952
Diseaseamino acid measurement

IMPG1 SYNE1 CFAP20DC CD6 SUSD5 HHAT LRP2 SENP6 NRG3

3.70e-036781339EFO_0005134
DiseaseIdiopathic Pulmonary Fibrosis

WNT5A MUC5B

4.00e-03211332C1800706

Protein segments in the cluster

PeptideGeneStartEntry
VNCCARETSLAENIW

BUB1B

501

O60566
DREVSCNFERDTCSW

MAMDC4

651

Q6UXC1
SFHSQCLQRWDDTTC

BRAP

286

Q7Z569
AEFAQVTNWSSCCLR

AAAS

141

Q9NRG9
LQNCCRALWNFTQEL

CFAP54

1636

Q96N23
TKAAWDSIQSFLQCC

CD53

131

P19397
NCRLFTCIDSTFNWQ

ERVK-18

296

O42043
FQLQCDWNTSDFCIT

ERVK-18

436

O42043
ENCRLLTCIDSTFNW

ERVK-19

406

O71037
ENCRLLTCIDSTFNW

ERVK-8

406

Q902F8
RFQLQCDWNTSDFCI

ERVK-8

546

Q902F8
NCRLLTCIDSTFNWQ

ERVK-9

406

Q9UKH3
FQLQCDWNTSDFCIT

ERVK-9

546

Q9UKH3
CWISDRAFCELLSSF

ACER2

191

Q5QJU3
LICCFGNTSWDRSLL

BCDIN3D

246

Q7Z5W3
QLACLVCKTLWNFSE

ARMC2

776

Q8NEN0
CLSQEQLRQWSSCRH

CCR7

346

P32248
CQCSWRTIEEVTDLQ

CFAP418

181

Q96NL8
LSNCWICHNFITRSS

ERVV-2

41

B6SEH9
IWFNESNRSCADCKA

ARAP2

691

Q8WZ64
SRQVLWINACFCNLS

CCN4

331

O95388
VTQSCNTDCELRWHV

ADAMTS20

896

P59510
RFRCQDESEAVCSEW

CHRNA7

446

P36544
FERTILCNSLVWSCA

BAZ1A

41

Q9NRL2
RWCFYSSCEQLDQLI

BAZ1A

891

Q9NRL2
DCLVCVNLSHWSLQT

C16orf46

101

Q6P387
VNETWTLENCTVARC

MUC5B

5016

Q9HC84
DEKWLCRQCVFATTT

MTF2

146

Q9Y483
RQWCNCAFLESSAKS

RAP1A

136

P62834
QVNWDCNLDRAASLC

P2RX4

256

Q99571
TWSRENIQALCECAL

INTS7

286

Q9NVH2
ACATNNANLLAWTCL

PIK3C2G

566

O75747
TLSNCSWRFNNSNLC

CD6

336

P30203
ELRCSDCIVWNRQQT

NRG3

51

P56975
TLQQCCDLSQLWFRE

CYFIP1

611

Q7L576
KRSICLDQNTQAWCD

PAN2

706

Q504Q3
TANLIDSENYWLRCC

TCTE1

121

Q5JU00
CSLLLCNRNDTAWDE

MKKS

371

Q9NPJ1
CNRNDTAWDELKLTC

MKKS

376

Q9NPJ1
ITRACCIARFWNQLD

MAP6

6

Q96JE9
SCFRCSECQDSLTNW

LIMK2

36

P53671
WVSICQQETFCLFDI

IMPG1

126

Q17R60
SILTNQSNCWLCEHL

ERVMER34-1

36

Q9H9K5
ACWILEDTACLEATN

LBHD1

161

Q9BQE6
QWSDIEEFCNRSCEV

CD55

86

P08174
LSNCWICHNFITRSS

ERVV-1

41

B6SEH8
DIWVFQFCLVIASCQ

PCNX1

1031

Q96RV3
NCLKNLDLWCFDVFS

PDE1B

156

Q01064
VCEFLNCSETTLRAW

PDE8B

586

O95263
RFETISLQTWCSCVA

FAM205A

351

Q6ZU69
RSETISLQTWCSCVA

FAM205BP

81

Q63HN1
LALNSTWGCFCRQDL

GP2

201

P55259
TWGCFCRQDLNSSDV

GP2

206

P55259
VFCSICIDLWLKNNS

OBI1

36

Q5W0B1
LNATDLCLASCVWQD

FBXO8

86

Q9NRD0
LCLASCVWQDLANDE

FBXO8

91

Q9NRD0
LQQWIKSSDTRCCEL

MARCHF8

111

Q5T0T0
WGINELFIDSCCSNR

KCNS3

106

Q9BQ31
NDSRTCVEFDDCQIW

LRP2

341

P98164
LQQCCDLSQLWFREF

CYFIP2

636

Q96F07
LTTWLAISNSFCNCV

GPR52

301

Q9Y2T5
ENCRLLTCIDSTFNW

ERVK-7

1166

P63135
RFQLQCDWNTSDFCI

ERVK-7

1306

P63135
RFRCQDESEAVCSEW

CHRFAM7A

356

Q494W8
RIFCSEDEQSRTCWL

GRB7

316

Q14451
AFWLSACRSLDLCTQ

OXER1

321

Q8TDS5
CVAQFRSQLLTWLCS

HHAT

126

Q5VTY9
ACDQLIFSWRCTEAE

PRICKLE4

151

Q2TBC4
QTCFVTSFEWCSKRQ

FBXO17

146

Q96EF6
TFCCLWIACVFNSTL

MALRD1

16

Q5VYJ5
LCCATNEDRSWVFDS

GATD1

131

Q8NB37
LWSACTSQVTRLCDL

FZR1

211

Q9UM11
SLIECWIQDCQSLEI

DNAH6

3016

Q9C0G6
WCQLCLSSQHQAIER

IL32

56

P24001
FECSSHCSELSWRQN

KLHL11

71

Q9NVR0
IWAQCFEITLELSCC

CPM

271

P14384
NCRLLTCIDSTFNWQ

ERVK-24

296

P61566
FQLQCDWNTSDFCIT

ERVK-24

436

P61566
ENCRLLTCIDSTFNW

ERVK-25

406

P61570
RFQLQCDWNTSDFCI

ERVK-25

546

P61570
ENCRLLTCIDSTFNW

ERVK-6

406

Q69384
RFQLQCDWNTSDFCI

ERVK-6

546

Q69384
NCRLLSCIDSTFNWQ

ERVK-7

296

P61567
FQLQCDWNTSDFCIT

ERVK-7

436

P61567
RANCLVQTTEWSACS

CCN2

196

P29279
SWSCSEFDLNEIRLI

FNIP2

36

Q9P278
CLMNLTTSSLICQWE

CSF3R

131

Q99062
NCRLLTCIDSTFNWQ

ERVK-21

406

P61565
FQLQCDWNTSDFCIT

ERVK-21

546

P61565
SEQEAWAVCLECSLS

KNDC1

51

Q76NI1
ENCRLLTCIDSTFNW

HERVK_113

406

Q902F9
RFQLQCDWNTSDFCI

HERVK_113

546

Q902F9
LLLTCAQDRQVCLWN

EML4

606

Q9HC35
CCSQLEERWQRLQSQ

EMILIN2

666

Q9BXX0
WDGLCCRSQFLQLVS

CENPI

446

Q92674
QVTIIADDNCRFLCW

BVES

216

Q8NE79
EASWIAFCQCESLLQ

HELB

271

Q8NG08
NLSWDCQENTTFSKC

CSF2RA

46

P15509
LCQAEVVCIRSTWNA

FOCAD

636

Q5VW36
WNFSRICCDVFVTLD

DRD3

96

P35462
VIRCQFSTFEQCQEW

MTMR3

96

Q13615
NSLSCSEQLNRCIRW

RASL11B

96

Q9BPW5
IASCSQDGRVFIWTC

SEC13

231

P55735
TLESQNLFCCLYRSW

VAC14

611

Q08AM6
RWSCERFSTSQVLCS

RNF135

291

Q8IUD6
FSVLWLVSQNCCRAS

RNF133

21

Q8WVZ7
RETAFTLLCNSCGEW

SUSD5

176

O60279
NFCLWNEDTSTLQCH

TMEM140

51

Q9NV12
DQWLDLCRQSNNLCL

SYNE1

4216

Q8NF91
CSRNICSLVNWLKSF

LRRTM3

316

Q86VH5
FNCQCQTWKLLREDS

MKLN1

431

Q9UL63
LTECCGNSNLRFEIW

PLEKHG4

981

Q58EX7
SRSSDECVVALCDQW

LARS1

516

Q9P2J5
FVSFLDQRRWKCNLC

SEC24A

441

O95486
WCRDSTTDEQLFRCE

RABGGTA

341

Q92696
LQNTSCDRESCWKEN

PNLDC1

216

Q8NA58
ICFTLAFCQIWRAIS

SLC9A4

386

Q6AI14
VVFNCSCRDVIGWTS

SIPA1L2

891

Q9P2F8
NCACRDVLAWTFSEQ

SIPA1

631

Q96FS4
SWQRCVTTCETALKQ

PNKP

401

Q96T60
FCSSCGELQLWLEKQ

SPTBN5

901

Q9NRC6
LWFCSQRCRSEAEAK

ADGRG5

501

Q8IZF4
HNSCLRSWLEQDTSC

AMFR

361

Q9UKV5
IWCNLCIDLVAFTSE

CFAP20DC

6

Q6ZVT6
NLSDLFQWAVSRALC

CHST6

116

Q9GZX3
SRLDELNLSWCFDFT

SKP2

256

Q13309
LWFRCSLCSATAQNL

ZNF451

751

Q9Y4E5
EKCCTRNNSVTLAWR

TRIM67

521

Q6ZTA4
SWFTCFACSLRTQAQ

SUN5

71

Q8TC36
LSTQNWCAKCNLSFR

ZNF488

271

Q96MN9
WCAKCNLSFRLTSDL

ZNF488

276

Q96MN9
CRSKQGCQFDLDSIW

WDFY3

1801

Q8IZQ1
ELFAQSCCALESWLE

SPTBN2

1386

O15020
SCCALESWLESLQAQ

SPTBN2

1391

O15020
WAEICETFTRDACSL

RMND5B

261

Q96G75
FTIDSTCILWDINDC

SLCO4C1

636

Q6ZQN7
LSSLLAQFFSCVSCW

TUT1

491

Q9H6E5
IWAQSQDCIAAALAC

TRPM2

641

O94759
LNWQDTAVLAQCSEC

TRIM51

41

Q9BSJ1
CSSLDCTVRIWTAEN

WDR97

706

A6NE52
QCEQNWGSLCSILSF

STC2

196

O76061
NDWLALLSLSCCESR

TECPR1

706

Q7Z6L1
CRSCIQQSWLDLQEL

TRIM75

36

A6NK02
HNSCWLIQAFSLACT

PIEZO2

1376

Q9H5I5
LNTSDLTKCEWCNVR

SENP6

486

Q9GZR1
ALTWNNEIHCSFCET

USP50

236

Q70EL3
LECSCFRTSIWDETL

RRAGB

216

Q5VZM2
SCSLKTCWLQLADFR

WNT5A

246

P41221
TCQILHWNFTDIRCL

PKHD1L1

1281

Q86WI1
ETRQCQALVIWTDCD

TOP3A

136

Q13472
SLEEWQCLDCAQRNL

ZNF479

26

Q96JC4
LWVDAQSTCERECSR

WFIKKN1

41

Q96NZ8
DSNICLVSWEDIQCT

USP41

336

Q3LFD5
QFISCVRGQWTECSD

ZDHHC7

196

Q9NXF8
SICDVWLQLFSRDQA

SLC29A4

151

Q7RTT9
CSLRLWSLDNKTCVQ

STRN4

701

Q9NRL3
AEFLDWSLCNLARSS

TBCD

226

Q9BTW9
ASRIAFWCQENCVAL

WDR4

246

P57081
DSNICLVSWEDIQCT

USP18

336

Q9UMW8
SDLTFNCSWCHVLQR

PLXDC1

316

Q8IUK5
CQQCDKRFRWSSDLN

ZNF75A

191

Q96N20
SVCCFKNEDNETLAW

TRPM8

1041

Q7Z2W7
FICECELSTFINWLN

TLR5

581

O60602
FTCSADCTIRRWDVL

WDR86

71

Q86TI4
WSENLFQCFNCSLCL

TNFRSF1A

136

P19438
CEECGKSFSWRSRLQ

ZNF45

306

Q02386
ADSWNQCDLVALTCF

TRPM4

861

Q8TD43
WEQLRKCCDSFNLLS

VWA3A

986

A6NCI4
CSLKCQEEFWIRSNN

ZRANB3

936

Q5FWF4
SQFQCTNGRCITLLW

VLDLR

36

P98155