Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DENND2A ARHGEF12 ARHGEF11 DENND1B RALGPS1 DENND4B RAB3IP IQSEC1

2.45e-052311028GO:0005085
GeneOntologyMolecularFunctionGTPase binding

FLNA RPH3AL AMBRA1 CDC42BPB DENND1B SYTL4 RAB3IP HPS6 GARRE1

9.55e-053601029GO:0051020
GeneOntologyMolecularFunctionsmall GTPase binding

FLNA RPH3AL CDC42BPB DENND1B SYTL4 RAB3IP HPS6 GARRE1

2.42e-043211028GO:0031267
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

ARHGEF12 ARHGEF11 HEG1 GPR174 RALGPS1 DENND4B IQSEC1 AUTS2 CGNL1 ARHGAP20

6.57e-0633310310GO:0051056
GeneOntologyCellularComponentanchoring junction

FLNA COL17A1 AMBRA1 CDC42BPB ITGB4 SPTBN4 HEG1 KCNA1 SH3PXD2A TLE2 PKP3 ABCB11 CGNL1 SSH2 MMP13

7.62e-0597610215GO:0070161
HumanPhenoAbnormality of the fifth metatarsal bone

FLNA RIPK4 CDC42BPB

2.03e-059333HP:0008089
HumanPhenoSkin detachment

COL17A1 ITGB4

4.07e-052332HP:0032156
MousePhenodermal-epidermal separation

COL17A1 ITGB4 AHDC1

1.65e-059833MP:0011160
MousePhenoabnormal epidermal-dermal junction morphology

COL17A1 ITGB4 AHDC1

4.27e-0512833MP:0011159
DomainuDENN

DENND2A DENND1B DENND4B

5.35e-05141013SM00800
DomainuDENN

DENND2A DENND1B DENND4B

6.66e-05151013PF03456
DomainUDENN

DENND2A DENND1B DENND4B

8.17e-05161013PS50946
DomainDDENN

DENND2A DENND1B DENND4B

8.17e-05161013PS50947
DomainDENN

DENND2A DENND1B DENND4B

8.17e-05161013SM00799
DomaindDENN

DENND2A DENND1B DENND4B

8.17e-05161013SM00801
DomainDENN

DENND2A DENND1B DENND4B

8.17e-05161013PF02141
DomaindDENN_dom

DENND2A DENND1B DENND4B

8.17e-05161013IPR005112
DomainuDENN_dom

DENND2A DENND1B DENND4B

8.17e-05161013IPR005113
DomaindDENN

DENND2A DENND1B DENND4B

8.17e-05161013PF03455
DomainDENN

DENND2A DENND1B DENND4B

8.17e-05161013PS50211
DomainDENN_dom

DENND2A DENND1B DENND4B

8.17e-05161013IPR001194
DomainRGS-like

ARHGEF12 ARHGEF11

8.66e-0531012PF09128
DomainRGS-like_dom

ARHGEF12 ARHGEF11

8.66e-0531012IPR015212
Domain-

ARHGEF12 ARHGEF11 CDC42BPB SHC3 SPTBN4 PTPN13 RALGPS1 IQSEC1 ARHGAP20

2.70e-0439110192.30.29.30
DomainPH_dom-like

ARHGEF12 ARHGEF11 CDC42BPB SHC3 SPTBN4 PTPN13 RALGPS1 IQSEC1 ARHGAP20

5.03e-044261019IPR011993
DomainPH

ARHGEF12 ARHGEF11 CDC42BPB SPTBN4 RALGPS1 IQSEC1 ARHGAP20

7.84e-042781017SM00233
DomainPH_DOMAIN

ARHGEF12 ARHGEF11 CDC42BPB SPTBN4 RALGPS1 IQSEC1 ARHGAP20

8.01e-042791017PS50003
DomainPH_domain

ARHGEF12 ARHGEF11 CDC42BPB SPTBN4 RALGPS1 IQSEC1 ARHGAP20

8.18e-042801017IPR001849
DomainPDZ

HTRA2 ARHGEF12 ARHGEF11 CYTIP PTPN13

1.01e-031411015PF00595
DomainPDZ

HTRA2 ARHGEF12 ARHGEF11 CYTIP PTPN13

1.26e-031481015SM00228
Domain-

HTRA2 ARHGEF12 ARHGEF11 CYTIP PTPN13

1.33e-0315010152.30.42.10
DomainPDZ

HTRA2 ARHGEF12 ARHGEF11 CYTIP PTPN13

1.37e-031511015PS50106
DomainPDZ

HTRA2 ARHGEF12 ARHGEF11 CYTIP PTPN13

1.41e-031521015IPR001478
DomainFYVE_2

RPH3AL SYTL4

1.54e-03111012PF02318
DomainRABBD

RPH3AL SYTL4

1.84e-03121012PS50916
DomainRab_BD

RPH3AL SYTL4

1.84e-03121012IPR010911
Domain-

DCAF1 PLXNA3 WDR88 AMBRA1 DCAF12L1 UTP15 TLE2

2.21e-0333310172.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF1 PLXNA3 WDR88 AMBRA1 DCAF12L1 UTP15 TLE2

2.29e-033351017IPR015943
DomainIon_trans_dom

KCNV1 KCNA1 CACNA1I TRPV5

3.41e-031141014IPR005821
DomainIon_trans

KCNV1 KCNA1 CACNA1I TRPV5

3.41e-031141014PF00520
DomainChannel_four-helix_dom

KCNV1 KCNA1 CACNA1I

3.63e-03571013IPR027359
Domain-

KCNV1 KCNA1 CACNA1I

3.63e-035710131.20.120.350
DomainWD_REPEATS_1

DCAF1 WDR88 AMBRA1 DCAF12L1 UTP15 TLE2

4.01e-032781016PS00678
DomainWD_REPEATS_2

DCAF1 WDR88 AMBRA1 DCAF12L1 UTP15 TLE2

4.08e-032791016PS50082
DomainWD_REPEATS_REGION

DCAF1 WDR88 AMBRA1 DCAF12L1 UTP15 TLE2

4.08e-032791016PS50294
DomainWD40_repeat_dom

DCAF1 WDR88 AMBRA1 DCAF12L1 UTP15 TLE2

5.52e-032971016IPR017986
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SLC4A7 MAP7 FAM83H NEK4 PTPN13 DENND1B SH3PXD2A IQSEC1 NADK KMT2A FNIP1 FAM53B CGNL1 SSH2 KIF13A SRRM2 SH3RF3 GARRE1 CRTC2

1.04e-118611041936931259
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PRUNE2 HECW1 ARHGEF12 ARHGEF11 RALGPS1 SRRM2 GARRE1

2.92e-0810410479205841
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

NEK4 C1orf198 DENND1B UTP15 PKP3 HPS6 IQSEC1 FAM53B SSH2 SNAPC2 EPN1 TRIM37 THRAP3 CFAP410 CRTC2 BEGAIN

8.02e-0810381041626673895
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 RPH3AL PPFIA2 CDC42BPB AHDC1 SPTBN4 PTPN13 DENND1B SH3PXD2A RALGPS1 PKP3 RAB3IP AUTS2 FNIP1 ANKRD12 SH3RF3 THRAP3 CREB3L2

4.23e-0714891041828611215
Pubmed

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.

COL17A1 ITGB4 PKP3 MMP13

7.66e-0724104428604778
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLXNA3 FLNA PCNX3 AMBRA1 ARHGEF11 CDC42BPB ITGB4 AHDC1 ELAC2 FAM83H HEG1 GAREM2 RALGPS1 HPS6 NADK

1.05e-0611051041535748872
Pubmed

Novel interactors and a role for supervillin in early cytokinesis.

FLNA PCNX3 SH3PXD2A KMT2A

1.46e-0628104420309963
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

DENND2A DENND1B DENND4B RAB3IP

4.62e-0637104420937701
Pubmed

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.

ARHGEF12 ARHGEF11 KMT2A

5.60e-0612104312123608
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

HECW1 ARHGEF12 ARHGEF11 CDC42BPB SPTBN4 KCNA1 RAB3IP IQSEC1 SSH2 THRAP3 LRRFIP2 BEGAIN PROX1

6.21e-069631041328671696
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA HTRA2 ZGRF1 CGNL1 KIF13A SRRM2 THRAP3

6.96e-06234104736243803
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

NEK4 VIPAS39 PTPN13 SH3PXD2A NADK SH3RF3 GARRE1 TRIM37 CRTC2

8.11e-06446104924255178
Pubmed

Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study.

ARHGEF12 ARHGEF11

8.86e-062104224106280
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DCAF1 HTRA2 AMBRA1 MCM2 MAP7 NEK4 PTPN13 SH3PXD2A RAB3IP RTL9 NADK FAM53B SH3RF3 CFAP410 CRTC2

9.15e-0613211041527173435
Pubmed

Cbfb regulates bone development by stabilizing Runx family proteins.

SOX5 RUNX1 MMP13

1.71e-0517104325262822
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

FLNA ITGB4 SPTBN4

2.05e-0518104312119179
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FLNA MCM2 MAP7 ITGB4 PKP3 KIF13A SRRM2 THRAP3 BEGAIN

2.10e-05503104916964243
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DENND2A FLNA PPFIA2 ARHGEF12 MAP7 ARHGEF11 CDC42BPB SPTBN4 KCNA1 IQSEC1 KMT2A CGNL1 SSH2 THRAP3 LRRFIP2

2.33e-0514311041537142655
Pubmed

Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells.

ARHGEF12 ARHGEF11

2.65e-053104215143072
Pubmed

Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription.

RUNX1 TLE2

2.65e-053104210825294
Pubmed

Identification of functional cooperative mutations of SETD2 in human acute leukemia.

RUNX1 KMT2A

2.65e-053104224509477
Pubmed

The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.

TRPV5 KLB

2.65e-053104216239475
Pubmed

Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).

ARHGEF12 ARHGEF11

2.65e-053104221454492
Pubmed

Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors.

ARHGEF12 ARHGEF11

2.65e-053104212220504
Pubmed

HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway.

ARHGEF12 ARHGEF11

2.65e-053104220844236
Pubmed

B plexins activate Rho through PDZ-RhoGEF.

ARHGEF12 ARHGEF11

2.65e-053104212372594
Pubmed

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer.

DENND1B FNIP1

2.65e-053104222977732
Pubmed

Direct interaction between the intracellular domains of bullous pemphigoid antigen 2 (BP180) and beta 4 integrin, hemidesmosomal components of basal keratinocytes.

COL17A1 ITGB4

2.65e-05310429500991
Pubmed

Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms.

ARHGEF11 IQSEC1

2.65e-053104220613766
Pubmed

Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.

ARHGEF12 ARHGEF11

2.65e-053104226627240
Pubmed

IS THE AMPLIFICATION OF c-MYC, MLL AND RUNX1 GENES IN AML AND MDS PATIENTS WITH TRISOMY 8, 11 AND 21 A FACTOR FOR A CLONAL EVOLUTION IN THEIR KARYOTYPE?

RUNX1 KMT2A

2.65e-053104226214902
Pubmed

Distinct mechanisms of regulation of the ITGA6 and ITGB4 genes by RUNX1 in myeloid cells.

RUNX1 ITGB4

2.65e-053104228926098
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

SOX5 FLNA HECW1 PPFIA2 CYTIP SPTBN4 SNAPC2 THRAP3 BEGAIN

4.83e-05560104921653829
Pubmed

Relationships between AML1-ETO and MLL-AF9 fusion gene expressions and hematological parameters in acute myeloid leukemia.

RUNX1 KMT2A

5.29e-054104233431365
Pubmed

Definitive hematopoiesis requires the mixed-lineage leukemia gene.

RUNX1 KMT2A

5.29e-054104215030765
Pubmed

Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature.

RUNX1 PROX1

5.29e-054104217908929
Pubmed

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180.

COL17A1 ITGB4

5.29e-05410429660880
Pubmed

Extravascular endothelial and hematopoietic islands form through multiple pathways in midgestation mouse embryos.

RUNX1 PROX1

5.29e-054104227105579
Pubmed

Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signaling.

COL17A1 ITGB4

5.29e-054104224505282
Pubmed

Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.

COL17A1 ITGB4

5.29e-054104214668477
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

AMBRA1 FAM83H PTPN13 FNIP1 GARRE1 THRAP3

7.27e-05232104625515538
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PPFIA2 C1orf198 SH3PXD2A RAB3IP IQSEC1 SRRM2 BEGAIN

8.59e-05347104717114649
Pubmed

Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.

ARHGEF12 ARHGEF11

8.80e-055104212515866
Pubmed

Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1 and NRAS in 269 patients with MDS or secondary AML.

RUNX1 KMT2A

8.80e-055104220520634
Pubmed

Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.

ARHGEF12 ARHGEF11

8.80e-055104212183458
Pubmed

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.

RUNX1 KMT2A

8.80e-055104222012064
Pubmed

Structure and function of hemidesmosomes: more than simple adhesion complexes.

COL17A1 ITGB4

8.80e-055104210201522
Pubmed

Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3.

NKX2-5 PROX1

8.80e-055104222647876
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

HTRA2 AMBRA1 PKP3 IQSEC1 SRRM2 THRAP3 LRRFIP2

9.56e-05353104727545878
Pubmed

Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.

FLNA MAP7 PKP3 SRRM2 LRRFIP2

1.20e-04159104534537242
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

FLNA SLC4A7 NADK SRRM2 THRAP3 CRTC2

1.22e-04255104615324660
Pubmed

The incidence of T-cell receptor gene rearrangements in childhood B-lineage acute lymphoblastic leukemia is related to immunophenotype and fusion oncogene expression.

RUNX1 KMT2A

1.32e-046104216386788
Pubmed

Gβγ-independent recruitment of G-protein coupled receptor kinase 2 drives tumor necrosis factor α-induced cardiac β-adrenergic receptor dysfunction.

NKX2-5 TNFRSF1B

1.32e-046104223785004
Pubmed

[Role of molecular screening for common fusion genes in the diagnosis and classification of leukemia].

RUNX1 KMT2A

1.32e-046104215968309
Pubmed

Interaction of Necl-4/CADM4 with ErbB3 and integrin α6 β4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly.

ITGB4 PTPN13

1.32e-046104223611113
Pubmed

Junctional Epidermolysis Bullosa

COL17A1 ITGB4

1.32e-046104220301304
Pubmed

A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis.

ARHGEF12 ARHGEF11

1.32e-046104220300064
Pubmed

Potent activation of RhoA by Galpha q and Gq-coupled receptors.

ARHGEF12 ARHGEF11

1.32e-046104212016230
Pubmed

Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.

EPN1 PROX1

1.32e-046104230102256
Pubmed

Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs).

ARHGEF12 ARHGEF11

1.32e-046104215755723
Pubmed

BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.

SPTBN4 KCNA1

1.32e-046104215381686
Pubmed

Tissue-Specific Roles for the Slit-Robo Pathway During Heart, Caval Vein, and Diaphragm Development.

ROBO4 NKX2-5

1.84e-047104235343246
Pubmed

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.

TLE2 NKX2-5

1.84e-047104224024827
Pubmed

PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.

ARHGEF12 ARHGEF11

1.84e-047104223467409
Pubmed

The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.

COL17A1 ITGB4

1.84e-047104210637308
Pubmed

Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.

RIPK4 ITGB4

1.84e-047104228507225
Pubmed

Yap1 Regulates Multiple Steps of Chondrocyte Differentiation during Skeletal Development and Bone Repair.

RUNX1 MMP13

1.84e-047104226923596
Pubmed

Isolation of cardiac cells from E8.5 yolk sac by ALCAM (CD166) expression.

RUNX1 NKX2-5

1.84e-047104217964124
Pubmed

Runx1 and Runx2 cooperate during sternal morphogenesis.

SOX5 RUNX1

1.84e-047104220181744
Pubmed

Maternal iron deficiency perturbs embryonic cardiovascular development in mice.

NKX2-5 PROX1

1.84e-047104234103494
Pubmed

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

DCAF1 AMBRA1 DCAF12L1

1.87e-0437104316949367
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DENND2A AMBRA1 MCM2 RALGPS1 AUTS2 FAM53B ARHGAP20 GARRE1

1.95e-04529104814621295
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DCAF1 ARHGEF12 RNF157 DENND4B FNIP1 ANKRD12 SRRM2

2.29e-04407104712693553
Pubmed

Dynamic expression of Runx1 in skin affects hair structure.

RUNX1 ITGB4

2.45e-048104217011173
Pubmed

Loss of Asb2 Impairs Cardiomyocyte Differentiation and Leads to Congenital Double Outlet Right Ventricle.

FLNA NKX2-5

3.14e-049104232179481
Pubmed

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.

ARHGEF12 ARHGEF11

3.14e-049104216192269
Pubmed

Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.

EPN1 PROX1

3.14e-049104225314967
Pubmed

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

COL17A1 ITGB4

3.14e-049104212482924
Pubmed

Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development.

FLNA NKX2-5

3.14e-049104225953344
Pubmed

Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier.

SPTBN4 KCNA1

3.14e-049104225653379
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

ARRDC5 NUTM2D LIX1L RIPK4 ELAC2 RNF157 SOCS7 TSFM RETREG3 DENND1B CARD9 SH3PXD2A

3.43e-0412421041230973865
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

PLXNA3 HECW1 CDC42BPB KCNV1 KMT2A SSH2 GALNT6 MMP13 THRAP3

3.51e-04730104934857952
Pubmed

Network organization of the human autophagy system.

DCAF1 FLNA HTRA2 AMBRA1 MCM2 SH3PXD2A FNIP1

3.51e-04437104720562859
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

PRUNE2 ARHGEF12 ARHGEF11 RNF157 NEK4 KLB

3.67e-04313104620800603
Pubmed

ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.

HTRA2 MAP7 ELAC2 TRIM37

3.78e-04113104434474245
Pubmed

A comparative transcriptional map of a region of 250 kb on the human and mouse X chromosome between the G6PD and the FLN1 genes.

PLXNA3 FLNA

3.92e-041010427490070
Pubmed

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function.

RUNX1 PROX1

3.92e-0410104237842094
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

FLNA SLC4A7 RPH3AL ITGB4 PTPN13 ANKRD12

4.26e-04322104626514267
Pubmed

Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants.

AMBRA1 RIPOR3 ITGB4 FAM53B

4.32e-04117104412107410
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

FLNA MAP7 KMT2A SRRM2 THRAP3

4.33e-04210104516565220
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

SLC4A7 NUTM2D MAP7 ITGB4 TSFM C1orf198 TEX264 PKP3 KIF13A THRAP3

4.63e-049251041028986522
Pubmed

Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis.

ITGB4 PKP3

4.79e-0411104221844209
Pubmed

ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer.

PCNX3 EPN1

4.79e-0411104234927784
Pubmed

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

COL17A1 ITGB4

4.79e-041110428707838
Pubmed

Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis.

COL17A1 ITGB4

4.79e-0411104235941116
Pubmed

Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.

COL17A1 ITGB4

4.79e-0411104212802069
Pubmed

Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting Complex.

DCAF1 MCM2

4.79e-0411104230100344
Pubmed

Runx1-Stat3-Tgfb3 signaling network regulating the anterior palatal development.

RUNX1 MMP13

4.79e-0411104230046048
Pubmed

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

COL17A1 ITGB4

4.79e-0411104210811835
Pubmed

Current insights into the formation and breakdown of hemidesmosomes.

COL17A1 ITGB4

4.79e-0411104216757171
InteractionYWHAB interactions

SLC4A7 MCM2 RIPK4 MAP7 ITGB4 FAM83H NEK4 VIPAS39 PTPN13 DENND1B SH3PXD2A RALGPS1 NADK KMT2A FAM53B CGNL1 SSH2 SRRM2 SH3RF3 GARRE1 CFAP410 CRTC2

6.76e-09101410322int:YWHAB
InteractionYWHAG interactions

FLNA SLC4A7 MCM2 RIPK4 MAP7 FAM83H NEK4 PTPN13 DENND1B SH3PXD2A IQSEC1 NADK KMT2A FNIP1 FAM53B CGNL1 SSH2 KIF13A SRRM2 SH3RF3 GARRE1 THRAP3 CFAP410 CRTC2

1.28e-08124810324int:YWHAG
InteractionYWHAE interactions

DCAF1 FLNA SLC4A7 MCM2 RIPK4 MAP7 FAM83H NEK4 PTPN13 DENND1B SH3PXD2A RAB3IP NADK KMT2A FAM53B CGNL1 SSH2 SRRM2 SH3RF3 GARRE1 CFAP410 CRTC2 LRRFIP2

6.73e-08125610323int:YWHAE
InteractionSFN interactions

SLC4A7 MCM2 FAM83H NEK4 PTPN13 DENND1B SH3PXD2A PKP3 RAB3IP NADK KMT2A FAM53B CGNL1 SSH2 KIF13A SRRM2 GARRE1

7.71e-0869210317int:SFN
InteractionCBY1 interactions

MAP7 PTPN13 SH3PXD2A RAB3IP NADK FAM53B SH3RF3 CFAP410 CRTC2

3.97e-071821039int:CBY1
InteractionYWHAH interactions

SLC4A7 MCM2 RIPK4 MAP7 FAM83H PTPN13 DENND1B SH3PXD2A NADK KMT2A FNIP1 FAM53B CGNL1 SSH2 SRRM2 SH3RF3 GARRE1 CFAP410 CRTC2

2.76e-06110210319int:YWHAH
InteractionYWHAQ interactions

FLNA SLC4A7 MCM2 RIPK4 MAP7 ITGB4 FAM83H PTPN13 DENND1B SH3PXD2A NADK KMT2A FAM53B CGNL1 SSH2 GARRE1 TRIM37 CFAP410 CRTC2

3.40e-06111810319int:YWHAQ
InteractionGIGYF1 interactions

SPAG8 PTPN13 SH3PXD2A NADK SH3RF3 GARRE1 TRIM37 CRTC2

3.53e-061771038int:GIGYF1
InteractionTLE3 interactions

FLNA RUNX1 AHDC1 FAM83H SPTBN4 TLE2 AUTS2 KMT2A NKX2-5 SRRM2 CRTC2

3.54e-0637610311int:TLE3
InteractionKSR1 interactions

DCAF1 RIPK4 PTPN13 SH3PXD2A NADK SH3RF3 CRTC2

5.18e-061321037int:KSR1
InteractionYWHAZ interactions

SLC4A7 PPFIA2 MCM2 RIPK4 MAP7 FAM83H NEK4 PTPN13 DENND1B SH3PXD2A NADK KMT2A FAM53B CGNL1 SSH2 GARRE1 TRIM37 CFAP410 CRTC2

3.51e-05131910319int:YWHAZ
InteractionFAM124B interactions

ISCA2 ARHGEF11 CARD9 NADK TRIM37

3.61e-05731035int:FAM124B
InteractionSH3PXD2A interactions

NEK4 PTPN13 SH3PXD2A RAB3IP NADK SH3RF3

5.04e-051281036int:SH3PXD2A
InteractionKIF20A interactions

FLNA AMBRA1 MAP7 CDC42BPB FAM83H SPTBN4 PKP3 SSH2 GALNT6 KIF13A EPN1 SRRM2 TRPV5 TRIM37 THRAP3 KLB

8.41e-05105210316int:KIF20A
InteractionDCAF7 interactions

SOX5 FLNA AMBRA1 SOCS7 NEK4 RAB3IP AUTS2 SRRM2 CFAP410

1.14e-043681039int:DCAF7
InteractionCGN interactions

ARHGEF11 PTPN13 SH3PXD2A NADK SH3RF3 CRTC2

1.31e-041521036int:CGN
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND2A DENND1B DENND4B FNIP1

1.50e-0625624504
GeneFamilyPDZ domain containing

HTRA2 ARHGEF12 ARHGEF11 CYTIP PTPN13

1.73e-041526251220
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF1 AMBRA1

1.71e-0318622498
GeneFamilyWD repeat domain containing

WDR88 AMBRA1 DCAF12L1 UTP15 TLE2

2.03e-03262625362
CoexpressionLASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN

DCAF1 SLC4A7 ARHGEF12 AHDC1 NEK4 TEX264 SH3PXD2A GPR153 HPS6 IQSEC1 NADK KMT2A TNFRSF1B THRAP3

3.76e-0680710414M14594
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PPFIA2 CYTIP SPTBN4 RALGPS1 CGNL1 CREB3L2

2.59e-071841047e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 AUTS2 CGNL1 LRRC36

3.34e-071911047a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 AUTS2 CGNL1 LRRC36

3.34e-071911047e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 PPFIA2 RALGPS1 CGNL1 CREB3L2 PROX1

3.46e-071921047562df5e87038c500dd3a003fe5374cb31946b145
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

PPFIA2 RUNX1 RNF157 SH3PXD2A RTL9 MMP13

2.42e-0616410469b4a6007abae992db871d9f6f731d5af724de30d
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RIPK4 MAP7 KCNV1 PKP3 GALNT6 LRRC36

2.68e-06167104625af48c640e67848594f5902867ba325fc105da4
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA HTRA2 CYTIP NADK SSH2 TNFRSF1B

2.88e-061691046ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA HTRA2 CYTIP NADK SSH2 TNFRSF1B

2.88e-061691046c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 DENND2A SHC3 RTL9 AUTS2 SH3RF3

4.14e-061801046280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 DENND2A SHC3 RTL9 AUTS2 SH3RF3

4.14e-061801046fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 PPFIA2 RALGPS1 CGNL1 CREB3L2

5.15e-0618710467ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

COL17A1 RIPK4 MAP7 ITGB4 PTPN13 MMP13

5.15e-0618710468407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PPFIA2 SYTL4 RALGPS1 CGNL1 CREB3L2

5.31e-0618810462ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 AUTS2 LRRC36

5.47e-061891046dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

SOX5 COL17A1 RIPK4 ITGB4 PTPN13 MMP13

5.64e-061901046ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DENND2A RIPOR3 RAB3IP CGNL1 PROX1

5.64e-06190104659bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 PPFIA2 RALGPS1 CGNL1 CREB3L2

5.64e-0619010463dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 AUTS2 LRRC36

5.81e-06191104634cc997e4e5c727495f321e6807a84aa124da486
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PPFIA2 SYTL4 RALGPS1 CGNL1 CREB3L2

5.81e-061911046963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 FLNA PPFIA2 SH3PXD2A SH3RF3 CREB3L2

5.81e-06191104604c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 AUTS2 LRRC36

5.99e-06192104658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

SOX5 COL17A1 RIPK4 ITGB4 PTPN13 MMP13

5.99e-0619210469b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 MAP7 SHC3 PTPN13 AUTS2 LRRC36

6.17e-061931046fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

SOX5 DENND2A HECW1 PPFIA2 AUTS2 SH3RF3

6.17e-061931046e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 AUTS2 LRRC36

6.17e-061931046738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 MAP7 SHC3 PTPN13 AUTS2 LRRC36

6.17e-061931046f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellfacs-Tongue|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 RIPK4 ITGB4 FAM83H PTPN13 PKP3

6.54e-06195104677128895db9221a64a171082d468ebcd6380c936
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA CYTIP DENND4B NADK TNFRSF1B

3.48e-051581045121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PPFIA2 RALGPS1 CGNL1 PROX1

3.70e-05160104503b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYTIP GPR174 RALGPS1 CACNA1I PROX1

4.41e-0516610454b31d2755108b2815316411a38bfb11fd30ef98a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA HTRA2 CYTIP NADK TNFRSF1B

4.67e-0516810454b5be7c6662eceddf90a65015f12908278d1664e
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA CYTIP NADK SSH2 TNFRSF1B

4.67e-051681045c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA HTRA2 CYTIP NADK TNFRSF1B

4.67e-051681045689c41f6e9f65381570991cc311cba49a57ec955
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA CYTIP NADK SSH2 TNFRSF1B

4.67e-051681045c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA HTRA2 CYTIP NADK TNFRSF1B

4.80e-051691045b059304543876f514d5c7214f1f0a2da00f10a67
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA HTRA2 CYTIP NADK TNFRSF1B

4.80e-051691045945f737984c4de70a4e9c214053b005358053dd5
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA CYTIP CARD9 NADK TNFRSF1B

4.80e-051691045907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

ARHGEF12 MAP7 SHC3 PTPN13 AUTS2

4.94e-051701045269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

RIPK4 PTPN13 RP1L1 ABCB11 MMP13

5.08e-051711045adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPK4 CYTIP GPR174 PKP3 CACNA1I

5.08e-051711045c6fc9ef9735dbf5314a4c7dac2b2954b0985ae4d
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPK4 CYTIP GPR174 PKP3 CACNA1I

5.08e-05171104555b194a9bf4d3e4b5d96e0d1298424359c441cbb
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

C16orf90 COL17A1 RIPK4 ITGB4 MMP13

5.22e-051721045e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCelldroplet-Lung-nan-21m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 HTRA2 CYTIP NADK TNFRSF1B

5.22e-05172104551bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCelldroplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 HTRA2 CYTIP NADK TNFRSF1B

5.22e-051721045be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 RIPOR3 CGNL1 PROX1

5.22e-0517210451565f38266891c3acf49778838de134c5dee5460
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

COL17A1 RPH3AL SYTL4 MMP13

5.41e-05881044b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

COL17A1 RPH3AL SYTL4 MMP13

5.41e-058810447992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

COL17A1 RPH3AL SYTL4 MMP13

5.41e-05881044b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCelldroplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTRA2 CYTIP NADK SSH2 TNFRSF1B

5.66e-051751045c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTRA2 CYTIP NADK SSH2 TNFRSF1B

5.66e-05175104561fbd8f685d3daad46449e4c0386a38886496566
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 SYTL4 CGNL1 PROX1

6.14e-0517810454df6218b20c2f076c22346d23260964cc0d73e65
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

SOX5 PRUNE2 FLNA PPFIA2 SH3RF3

6.30e-051791045a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL20A1 ITGB4 PTPN13 KCNA1 GALNT6

6.47e-051801045d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL20A1 ITGB4 PTPN13 KCNA1 GALNT6

6.47e-051801045dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL20A1 ITGB4 PTPN13 KCNA1 GALNT6

6.82e-051821045812ff2a50a510b18d865e89465dba1754a08ef61
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 PTPN13 AUTS2 CGNL1 LRRC36

7.00e-0518310456847c1252d6bb105524f812658112517fd351eab
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

SOX5 PTPN13 AUTS2 CGNL1 LRRC36

7.00e-0518310458e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOX5 FLNA SPTBN4 IQSEC1 TNFRSF1B

7.00e-051831045278064c9f0582463b83bf156d34e77f60187613b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 DENND1B CGNL1 PROX1

7.37e-05185104503f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 RIPK4 MAP7 ITGB4 FAM83H

7.75e-051871045fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOCS7 PTPN13 SYTL4 AUTS2 KIF13A

7.75e-051871045f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 PPFIA2 RALGPS1 CGNL1

7.95e-0518810453cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC4A7 RNF157 CYTIP GPR174 CACNA1I

8.15e-051891045df30478b288084a1bd48f660409dcc784040897c
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A AMBRA1 PTPN13 DENND1B PROX1

8.15e-051891045830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DENND2A RIPOR3 CGNL1 PROX1

8.35e-0519010451cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SOX5 SPTBN4 SH3PXD2A IQSEC1 TNFRSF1B

8.35e-051901045ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PPFIA2 RALGPS1 CGNL1 PROX1

8.35e-051901045b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA ARHGEF12 HEG1 SH3PXD2A CGNL1

8.35e-051901045d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 SYTL4 CGNL1 PROX1

8.56e-051911045f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA COL17A1 RUNX1 ITGB4 HEG1

8.56e-0519110458691eba35793e4e90f93d50c2145847ee51289f7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 DENND2A SHC3 AUTS2 SH3RF3

8.77e-0519210454022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 CGNL1

8.77e-051921045499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 DENND2A C1orf198 GALNT6 PROX1

8.77e-051921045b016e229300c183e14c0e2bba494bf49c7899112
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 SLC4A7 SYTL4 SH3PXD2A SRRM2

8.77e-0519210451304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 DENND2A C1orf198 GALNT6 PROX1

8.77e-051921045ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SOX5 MAP7 PTPN13 AUTS2 CGNL1

8.77e-051921045efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 DENND2A SHC3 AUTS2 SH3RF3

8.77e-0519210459333aba0d04203ccccad78d82bf6359922f810a7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX5 MAP7 SHC3 PTPN13 LRRC36

8.77e-051921045fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A SLC4A7 DENND1B CGNL1 PROX1

8.77e-051921045ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellfacs-MAT-Fat-3m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 ITGB4 GARRE1 TRIM37 PROX1

8.99e-051931045b32533afeff1905e188becaa09079e9699722e4b
ToppCellfacs-MAT-Fat-3m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 ITGB4 GARRE1 TRIM37 PROX1

8.99e-0519310452ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MAP7 PTPN13 RALGPS1 CGNL1

8.99e-0519310453866667dd221612589ae50f5c52f73a183a49ce6
ToppCelldroplet-Bladder-nan-24m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A7 COL17A1 ITGB4 FAM83H PKP3

8.99e-0519310459d7bc71c4ae871aad057d3beb6e06c929ae17203
ToppCellfacs-MAT-Fat-3m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 ITGB4 GARRE1 TRIM37 PROX1

8.99e-051931045e164f6403a8b541ced08a6feec915d2e855036ea
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC4A7 RNF157 CYTIP GPR174 CACNA1I

9.21e-0519410453d6f2d190dd50804afea299957cc44c2bb756134
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 SLC4A7 SYTL4 SH3PXD2A SRRM2

9.21e-05194104592b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ROBO4 ARHGEF12 HEG1 CGNL1 LRRC36

9.21e-051941045ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RPH3AL MAP7 SHC3 PTPN13 AUTS2

9.21e-05194104597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ROBO4 ARHGEF12 HEG1 CGNL1 LRRC36

9.21e-051941045cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 FLNA RIPOR3 SHC3 SH3RF3

9.44e-051951045803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 SLC4A7 DCAF12L1 SYTL4 SH3PXD2A

9.44e-051951045bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 ARHGEF12 HEG1 GARRE1 PROX1

9.44e-0519510457f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 FLNA RIPOR3 SHC3 SH3RF3

9.44e-0519510454f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX5 DENND2A FLNA PPFIA2 SH3RF3

9.67e-051961045754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 MAP7 PTPN13 DENND1B RALGPS1

9.67e-051961045eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAP7 SHC3 PTPN13 AUTS2 LRRC36

1.01e-041981045f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 AMBRA1 PTPN13 AUTS2 KIF13A

1.01e-0419810451996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAP7 SHC3 PTPN13 AUTS2 LRRC36

1.01e-0419810452e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAP7 SHC3 PTPN13 CGNL1 LRRC36

1.04e-041991045725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell(07)_Ionocytes|World / shred by cell type by condition

SLC4A7 RPH3AL AUTS2 ANKRD12 PROX1

1.04e-0419910458194777d367405a7840787e977854b5c07e3bd6b
DrugPiromidic acid [19562-30-2]; Up 200; 13.8uM; MCF7; HT_HG-U133A

SLC4A7 RUNX1 ITGB4 AUTS2 CACNA1I EPN1 CFAP410 BEGAIN

3.20e-0619510483335_UP
DrugSulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A

DCAF1 PRUNE2 RUNX1 CARD9 GPR153 TLE2 NKX2-5 PROX1

3.32e-0619610486101_UP
DrugChlorthalidone [77-36-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

SLC4A7 ITGB4 SOCS7 NADK FAM53B SNAPC2 KIF13A SRRM2

3.58e-0619810483198_DN
DrugGuanethidine sulfate [60-02-6]; Up 200; 13.4uM; HL60; HG-U133A

SLC4A7 AMBRA1 RUNX1 ELAC2 HEG1 TEX264 PKP3 NADK

3.72e-0619910481554_UP
DrugVerteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A

DCAF1 RUNX1 SPAG8 ITGB4 SOCS7 CARD9 CFAP410

3.10e-0519410473556_UP
DrugGuanethidine sulfate [60-02-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

RUNX1 ARHGEF11 ITGB4 SPTBN4 SH3PXD2A TLE2 CFAP410

3.30e-0519610473171_UP
DrugBergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A

PLXNA3 ROBO4 RPH3AL NADK CACNA1I CFAP410 BEGAIN

3.30e-0519610472726_UP
Druggenistein; Up 200; 10uM; MCF7; HT_HG-U133A

PLXNA3 AMBRA1 RUNX1 SPAG8 CACNA1I SRRM2 CFAP410

3.30e-0519610475232_UP
DrugBepridil hydrochloride [74764-40-2]; Down 200; 10uM; PC3; HT_HG-U133A

DENND2A SLC4A7 ARHGEF12 ITGB4 PTPN13 TLE2 PKP3

3.41e-0519710474613_DN
DrugTiletamine hydrochloride; Up 200; 15.4uM; PC3; HT_HG-U133A

AMBRA1 MAP7 RUNX1 PKP3 KIF13A SRRM2 CFAP410

3.41e-0519710477311_UP
DrugFlucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; PC3; HT_HG-U133A

RPH3AL MAP7 RUNX1 CARD9 KMT2A SNAPC2 EPN1

3.53e-0519810475102_UP
DrugBiperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; MCF7; HT_HG-U133A

DCAF1 COL17A1 RUNX1 HEG1 CARD9 TLE2 KIF13A

3.53e-0519810475644_UP
DrugMetoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A

PRUNE2 SLC4A7 RUNX1 CARD9 CACNA1I BEGAIN PROX1

3.53e-0519810476106_UP
DrugThiamphenicol [15318-45-3]; Down 200; 11.2uM; PC3; HT_HG-U133A

DCAF1 PLXNA3 SLC4A7 AMBRA1 RUNX1 ITGB4 SNAPC2

3.53e-0519810471826_DN
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

DCAF1 COL17A1 RUNX1 SH3PXD2A RALGPS1 NKX2-5 CACNA1I

3.53e-0519810474316_UP
DrugVancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; HL60; HT_HG-U133A

COL17A1 ARHGEF12 MAP7 SH3PXD2A KMT2A CACNA1I BEGAIN

3.64e-0519910472498_UP
DrugKarakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ARHGEF12 ITGB4 RALGPS1 CACNA1I MMP13 EPN1 SRRM2

3.64e-0519910473638_DN
DrugAmodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; HL60; HG-U133A

DCAF1 SLC4A7 AMBRA1 ARHGEF11 ELAC2 HEG1 NADK

3.76e-0520010471570_UP
DrugN-desmethylmethsuximide

CACNA1I TRIM37

6.18e-0531042CID000092154
DiseaseAmelogenesis Imperfecta

COL17A1 ITGB4 FAM83H

8.37e-06121013C0002452
Diseaseneuroimaging measurement

SOX5 ARHGEF12 ARHGEF11 ELAC2 RETREG3 NEK4 DENND1B SH3PXD2A RALGPS1 DENND4B FAM53B SSH2 SH3RF3 CRTC2

1.68e-05106910114EFO_0004346
DiseasePrecursor B-cell lymphoblastic leukemia

RUNX1 AUTS2 KMT2A

4.95e-05211013C1292769
Diseaseserum gamma-glutamyl transferase measurement

C16orf90 PCNX3 ARHGEF11 CDC42BPB SYTL4 RP1L1 ABCB11 KMT2A FAM53B CGNL1 PROX1 KLB

6.91e-0591410112EFO_0004532
DiseaseAdult junctional epidermolysis bullosa (disorder)

COL17A1 ITGB4

1.15e-0451012C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

COL17A1 ITGB4

1.15e-0451012C2608084
DiseaseBicuspid aortic valve

ROBO4 NKX2-5

1.15e-0451012C0149630
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

COL17A1 ITGB4

1.15e-0451012DOID:0060738 (implicated_via_orthology)
DiseaseJunctional Epidermolysis Bullosa

COL17A1 ITGB4

1.72e-0461012C0079301
Diseaseendometrial cancer (is_marker_for)

HTRA2 RUNX1 TNFRSF1B

2.35e-04351013DOID:1380 (is_marker_for)
Diseasejunctional epidermolysis bullosa (is_implicated_in)

COL17A1 ITGB4

2.41e-0471012DOID:3209 (is_implicated_in)
DiseaseBurkitt Lymphoma

RUNX1 AUTS2 KMT2A

2.56e-04361013C0006413
Diseasecortical thickness

SOX5 ARHGEF12 ELAC2 DENND1B SH3PXD2A RALGPS1 AUTS2 KMT2A FAM53B SSH2 KIF13A SH3RF3

4.24e-04111310112EFO_0004840
Diseasebrain measurement, neuroimaging measurement

SOX5 ELAC2 DENND1B SH3PXD2A RALGPS1 FAM53B SSH2 SH3RF3

6.14e-045501018EFO_0004346, EFO_0004464
Diseasecorneal resistance factor

ARHGEF12 PTPN13 DENND4B KMT2A FNIP1 FAM53B GALNT6

9.31e-044511017EFO_0010067
Diseasep-tau measurement

CYTIP AUTS2 LRRFIP2

1.96e-03721013EFO_0004763
Diseasepulse pressure measurement

SLC4A7 ARHGEF12 AHDC1 SPTBN4 DENND1B NADK ABCB11 FAM53B GARRE1 LRRFIP2 CREB3L2 KLB

2.86e-03139210112EFO_0005763
DiseaseSchizophrenia

SOX5 AMBRA1 ARHGEF11 SH3PXD2A GPR153 AUTS2 KMT2A CGNL1 TNFRSF1B

3.32e-038831019C0036341

Protein segments in the cluster

PeptideGeneStartEntry
PGDSRLLSTDASHSR

COL17A1

1276

Q9UMD9
LSSLSSAAETGRDPL

CFAP410

161

O43822
DPASLSSRLSDASAR

BEGAIN

191

Q9BUH8
SRILADSSTGLAPDS

ASB10

71

Q8WXI3
PQSIDRLSSLSSLGD

ARHGEF11

6

O15085
RLSSLSSLGDSAPER

ARHGEF11

11

O15085
RNSPGALTTRLATDA

ABCB11

851

O95342
ALSASRPESRKASGT

AHDC1

856

Q5TGY3
RTEGQTPSSSRLELS

AMBRA1

621

Q9C0C7
LLSEKDSESSSPRGR

ANKRD12

1756

Q6UB98
LVLSSDLEDGSPRRS

CARD9

421

Q9H257
SPDRDLGLESTLISS

ARHGEF12

1176

Q9NZN5
FGLSTDSLSRLRSPS

RAB3IP

151

Q96QF0
ESRSPRRGLALTSSS

RALGPS1

376

Q5JS13
SSRRTDALTSSPGRD

MCM2

31

P49736
LEPSRDGSLLLTSAT

DCAF1

1141

Q9Y4B6
SSPNLASDSDLSRRS

KCNA1

431

Q09470
SSSATLLNSPDRARR

MAP7

201

Q14244
SQSSLDLRREGSLSP

HECW1

926

Q76N89
TPSAERRSRLDSSEL

ARRDC5

236

A6NEK1
AGDRPSSTESDLRLR

IQSEC1

321

Q6DN90
NASRGSSLPRTLSKE

KIAA1109

3896

Q2LD37
LLSRRSLSGSADENP

EZHIP

356

Q86X51
SRSSSLDALGPTRKE

C1orf198

171

Q9H425
RALLDSPLDSGSLTS

KCNV1

6

Q6PIU1
AGPRLSASASSKELL

TSFM

36

P43897
ASTPELARRSSGLSR

FAM53B

251

Q14153
RAKSRSLSASPALGS

NADK

41

O95544
EGSELSPASSLRSQR

PCNX3

426

Q9H6A9
LLRTASSPDSLRSRA

PLXNA3

1601

P51805
PDSSTGRLLKLSSDL

LRRC36

386

Q1X8D7
PSLSLDAITSLRGET

MMP13

286

P45452
LRLLGSSDSPASASR

NEK4

476

P51957
SAESLLSLRPSALDS

GPR153

456

Q6NV75
SSRERLSDSSAPSSL

AUTS2

201

Q8WXX7
SVPGALSRELASTER

LIX1L

286

Q8IVB5
SESLNSSAPRGERSI

HEG1

516

Q9ULI3
LFPLLRTSDDTSGNR

GPR174

151

Q9BXC1
LEALRSSSLGSRTLD

CDC42BPB

846

Q9Y5S2
LTASLGPQARREASS

ISCA2

26

Q86U28
LIPRLSASSGRSSDA

ITGB4

1396

P16144
GELSARLEATLAPSS

NKX2-5

31

P52952
SDRASPTANSGLLRS

LRRFIP2

186

Q9Y608
GDLSSSSSLRRLLSG

FAM189B

631

P81408
LTPDLRALLTSGTSD

HTRA2

31

O43464
LDTRKLSRDGTGSPS

DENND2A

436

Q9ULE3
PVLDGARSRRSSSSS

CGNL1

286

Q0VF96
LKSSSLDRSSQRPLG

COL20A1

116

Q9P218
ASPSGDARRLTVSSL

FLNA

2326

P21333
RLPSALNRTSSDSAL

CRTC2

161

Q53ET0
ASDRISLQRSLGPDT

GALNT6

146

Q8NCL4
DRDSGIARSASLSSL

FNIP1

251

Q8TF40
TLEDSLTLSDSPRRA

CACNA1I

2031

Q9P0X4
ELGRALSAPLASTAT

GARRE1

36

O15063
LEARLPRDSLGSSAS

C16orf90

121

A8MZG2
GPALVDRNRLSSESS

CYTIP

231

O60759
LRRSSERLSDTPGSF

DENND4B

1131

O75064
DFDRLRTALPTSGSS

EPN1

406

Q9Y6I3
RGLSSSALPRLTEAE

KLB

796

Q86Z14
RTRSGRLSSSELSPL

KMT2A

756

Q03164
RASATLESSSGPARR

DCAF12L1

386

Q5VU92
SGSDRLPSRFLSAQS

FAM83H

826

Q6ZRV2
RTLEPSGEASTSLGR

HPS6

166

Q86YV9
SPRKRVSSSGLTDSL

DENND1B

646

Q6P3S1
GSSLLRVSGLESRPD

CREB3L2

456

Q70SY1
ARSSLSVSLEPESLG

PPFIA2

796

O75334
RELPTSSAISSALDR

PTPN13

366

Q12923
LSSSSLEDRLPSTGV

RPH3AL

216

Q9UNE2
TDSSAGELSSRRSLP

KIF13A

1751

Q9H1H9
RAAPSRGTARLDSSS

NUTM2D

561

Q5VT03
SQASRALTEPLSGRA

GAREM2

581

Q75VX8
LRDSALLTPGSKDST

ARHGAP20

271

Q9P2F6
LSAELSSRLSTAPDL

RUNX1

286

Q01196
DPGERPSLLTRASSS

RTL9

776

Q8NET4
STSRRDSLDKSGLFP

SYTL4

211

Q96C24
LSSSGQRLLSGSLDR

UTP15

256

Q8TED0
SSVAGSLSLRRAVDP

TRIM37

766

O94972
SASNLSLRGESPLSL

SLC4A7

266

Q9Y6M7
RSRSRSLDIQPSSEG

SPAG8

11

Q99932
RTISPLDRLSDSSSQ

RNF157

411

Q96PX1
RTAAALAPASLTSAR

SRRM2

2356

Q9UQ35
PDSGLATIRSSRSSK

PRUNE2

426

Q8WUY3
SPESLDLTRDTTSLR

PROX1

511

Q92786
LSSSGLRGLSSAARE

SHC3

76

Q92529
SRGSLSLSFEREPST

RIPK4

431

P57078
DLERSLPAVASLGSS

STARD3

11

Q14849
RDLSSSSSLSSRLGA

ROBO4

536

Q8WZ75
SSSLSSRLGADARDP

ROBO4

541

Q8WZ75
ATRGFLRSPSSDLDT

RETREG3

426

Q86VR2
ARAPSVRSLSLSLAD

PKP3

276

Q9Y446
GSASRASAVSELSPR

THRAP3

231

Q9Y2W1
RIDTRGLPADTSSSS

WDR88

441

Q6ZMY6
ERPLSRLSPERSSDS

ELAC2

201

Q9BQ52
ILSSPEDRGSSLSTA

SSH2

1096

Q76I76
SYLSDSDLRGPSLRS

RIPOR3

381

Q96MK2
LTPRARSEEGASSDS

RP1L1

521

Q8IWN7
GSLRELATSRTAPAA

SH3RF3

176

Q8TEJ3
PSEGSRRSSSDLITL

SH3PXD2A

811

Q5TCZ1
RETSAATLSPGASSR

TEX264

236

Q9Y6I9
GLEPLARRASDTLSA

SPTBN4

2156

Q9H254
RTRPGSFQSLSDALS

VIPAS39

116

Q9H9C1
RPSGELAASAASLTD

SOCS7

236

O14512
PELNSRTFISSGRSL

ZGRF1

91

Q86YA3
GESLSSTALGTPERR

SOX5

121

P35711
LESSASALDRRAPTR

TNFRSF1B

331

P20333
RDLVDSPASLASSLG

TLE2

266

Q04725
SSSSGNSLLRIRDLG

nan

46

Q6ZTI0
VSRSGRSPELSAAES

SNAPC2

216

Q13487
AESGTLARASLALPT

TRPV5

671

Q9NQA5
TTEATPRSLRASGSL

UNQ9165/PRO28630

41

Q6UXU0