Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiongranulocyte colony-stimulating factor receptor binding

PSG8 PSG1 PSG9

1.34e-0614323GO:0005130
GeneOntologyMolecularFunctionGPI anchor binding

PSG8 PSG1 PSG9

6.48e-0623323GO:0034235
GeneOntologyMolecularFunctionToll-like receptor binding

PSG8 PSG1 PSG9

1.33e-0529323GO:0035325
GeneOntologyMolecularFunctionfilamin binding

PSG8 PSG1 PSG9

1.33e-0529323GO:0031005
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

PSG8 PSG1 PSG9

2.16e-0534323GO:0015125
GeneOntologyMolecularFunctionglycolipid binding

PSG8 PSG1 PSG9

6.55e-0549323GO:0051861
GeneOntologyMolecularFunctionhistone deacetylase binding

DACT1 NCOR2 BCL3 BCOR

8.64e-05147324GO:0042826
GeneOntologyMolecularFunctionhistone H3K14 acetyltransferase activity

BRPF3 BRD1

8.89e-059322GO:0036408
GeneOntologyMolecularFunctionhistone H4K8 acetyltransferase activity

BRPF3 BRD1

1.36e-0411322GO:0043996
GeneOntologyMolecularFunctionhistone H4K5 acetyltransferase activity

BRPF3 BRD1

1.36e-0411322GO:0043995
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

NKX3-2 ZNF750 IRX6 IRX2 ZBTB4

1.45e-04320325GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

NKX3-2 ZNF750 IRX6 IRX2 ZBTB4

1.58e-04326325GO:0001217
GeneOntologyMolecularFunctionhistone H4K12 acetyltransferase activity

BRPF3 BRD1

1.63e-0412322GO:0043997
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

PSG8 PSG1 PSG9

1.90e-0470323GO:1901618
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

PSG8 PSG1 PSG9

2.15e-0473323GO:0170055
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

BRPF3 BRD1

2.58e-0415322GO:0010484
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

PSG8 PSG1 PSG9

4.00e-0490323GO:0008028
GeneOntologyMolecularFunctionhistone H4 acetyltransferase activity

BRPF3 BRD1

6.16e-0423322GO:0010485
GeneOntologyMolecularFunctionphosphatase binding

PSG8 PSG1 PSG9 SBF2

8.03e-04264324GO:0019902
GeneOntologyMolecularFunctionphosphatidylinositol binding

PSG8 PSG1 PSG9 SBF2

1.56e-03316324GO:0035091
GeneOntologyMolecularFunctionprotein homodimerization activity

ANKRD11 PSG8 TRIM68 PSG1 PSG9 ZBTB4

1.66e-03815326GO:0042803
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NKX3-2 ZNF750 IRX6 GCM2 BCOR IRX2 BARHL1 ZBTB4

1.72e-031459328GO:0000977
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

PSG8 PSG1 PSG9

1.72e-03149323GO:1990782
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

DACT1 NCOR2 TRIM68 BCL3 BCOR

2.17e-03582325GO:0140297
GeneOntologyMolecularFunctionprotein kinase binding

DACT1 PSG8 TRIM68 PSG1 PSG9 ZBTB4

2.35e-03873326GO:0019901
GeneOntologyMolecularFunctiongrowth factor receptor binding

PSG8 PSG1 PSG9

2.64e-03173323GO:0070851
GeneOntologyMolecularFunctionhistone acetyltransferase activity

BRPF3 BRD1

3.02e-0351322GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

BRPF3 BRD1

3.50e-0355322GO:0061733
GeneOntologyMolecularFunctionlipid transporter activity

PSG8 PSG1 PSG9

3.75e-03196323GO:0005319
GeneOntologyMolecularFunctionkinase binding

DACT1 PSG8 TRIM68 PSG1 PSG9 ZBTB4

3.94e-03969326GO:0019900
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

BRPF3 BRD1

4.16e-0360322GO:0034212
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

PSG8 PSG1 PSG9

4.36e-03207323GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

PSG8 PSG1 PSG9

4.42e-03208323GO:0005342
GeneOntologyMolecularFunctionprotein phosphatase binding

PSG8 PSG1 PSG9

4.54e-03210323GO:0019903
GeneOntologyMolecularFunctiontranscription corepressor activity

NCOR2 BCL3 BCOR

5.78e-03229323GO:0003714
GeneOntologyMolecularFunctioncalmodulin binding

PSG8 PSG1 PSG9

5.85e-03230323GO:0005516
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NKX3-2 ZNF750 IRX6 GCM2 IRX2 BARHL1 ZBTB4

6.12e-031412327GO:0000981
GeneOntologyMolecularFunctiontranscription factor binding

DACT1 NCOR2 TRIM68 BCL3 BCOR

6.51e-03753325GO:0008134
GeneOntologyMolecularFunctionactin binding

PSG8 EPS8L1 PSG1 PSG9

6.91e-03479324GO:0003779
GeneOntologyMolecularFunctionN-acetyltransferase activity

BRPF3 BRD1

6.93e-0378322GO:0008080
GeneOntologyMolecularFunctionhistone binding

RESF1 BRD1 PYGO1

8.63e-03265323GO:0042393
GeneOntologyMolecularFunctionphospholipid binding

PSG8 PSG1 PSG9 SBF2

1.10e-02548324GO:0005543
GeneOntologyMolecularFunctionprotein dimerization activity

ANKRD11 PSG8 TRIM68 PSG1 PSG9 ZBTB4

1.12e-021205326GO:0046983
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

PSG8 PSG1 PSG9

1.13e-02293323GO:0008514
GeneOntologyMolecularFunctionN-acyltransferase activity

BRPF3 BRD1

1.16e-02102322GO:0016410
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF750 IRX6 GCM2 BARHL1

1.18e-02560324GO:0001228
GeneOntologyMolecularFunctionacetyltransferase activity

BRPF3 BRD1

1.20e-02104322GO:0016407
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF750 IRX6 GCM2 BARHL1

1.22e-02566324GO:0001216
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NKX3-2 ZNF750 IRX6 GCM2 IRX2 ZBTB4

1.29e-021244326GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NKX3-2 ZNF750 IRX6 GCM2 IRX2 ZBTB4

1.43e-021271326GO:0000987
GeneOntologyMolecularFunctioncytokine receptor binding

PSG8 PSG1 PSG9

1.48e-02324323GO:0005126
GeneOntologyBiologicalProcessnegative regulation of brown fat cell proliferation

PSG8 PSG1 PSG9

1.22e-0614323GO:0070348
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immune response to tumor cell

PSG8 PSG1 PSG9

1.52e-0615323GO:0002856
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

PSG8 PSG1 PSG9

1.52e-0615323GO:0002859
GeneOntologyBiologicalProcessregulation of brown fat cell proliferation

PSG8 PSG1 PSG9

1.52e-0615323GO:0070347
GeneOntologyBiologicalProcesspositive regulation of homophilic cell adhesion

PSG8 PSG1 PSG9

1.52e-0615323GO:1903387
GeneOntologyBiologicalProcessinsulin receptor internalization

PSG8 PSG1 PSG9

1.87e-0616323GO:0038016
GeneOntologyBiologicalProcessbrown fat cell proliferation

PSG8 PSG1 PSG9

2.27e-0617323GO:0070342
GeneOntologyBiologicalProcessgranulocyte colony-stimulating factor signaling pathway

PSG8 PSG1 PSG9

2.27e-0617323GO:0038158
GeneOntologyBiologicalProcessinsulin catabolic process

PSG8 PSG1 PSG9

2.27e-0617323GO:1901143
GeneOntologyBiologicalProcessregulation of homophilic cell adhesion

PSG8 PSG1 PSG9

2.72e-0618323GO:1903385
GeneOntologyBiologicalProcessnegative regulation of hepatocyte proliferation

PSG8 PSG1 PSG9

3.80e-0620323GO:2000346
GeneOntologyBiologicalProcessnegative regulation of response to tumor cell

PSG8 PSG1 PSG9

4.43e-0621323GO:0002835
GeneOntologyBiologicalProcessnegative regulation of immune response to tumor cell

PSG8 PSG1 PSG9

4.43e-0621323GO:0002838
GeneOntologyBiologicalProcessnegative regulation of fat cell proliferation

PSG8 PSG1 PSG9

4.43e-0621323GO:0070345
GeneOntologyBiologicalProcessnegative regulation of granulocyte differentiation

PSG8 PSG1 PSG9

5.12e-0622323GO:0030853
GeneOntologyBiologicalProcessnegative regulation of platelet aggregation

PSG8 PSG1 PSG9

5.88e-0623323GO:0090331
GeneOntologyBiologicalProcessregulation of natural killer cell mediated cytotoxicity directed against tumor cell target

PSG8 PSG1 PSG9

5.88e-0623323GO:0002858
GeneOntologyBiologicalProcesspositive regulation of vasculogenesis

PSG8 PSG1 PSG9

6.71e-0624323GO:2001214
GeneOntologyBiologicalProcessregulation of natural killer cell mediated immune response to tumor cell

PSG8 PSG1 PSG9

6.71e-0624323GO:0002855
GeneOntologyBiologicalProcessnatural killer cell mediated cytotoxicity directed against tumor cell target

PSG8 PSG1 PSG9

6.71e-0624323GO:0002420
GeneOntologyBiologicalProcesscommon myeloid progenitor cell proliferation

PSG8 PSG1 PSG9

7.62e-0625323GO:0035726
GeneOntologyBiologicalProcessnatural killer cell mediated immune response to tumor cell

PSG8 PSG1 PSG9

7.62e-0625323GO:0002423
GeneOntologyBiologicalProcessregulation of fat cell proliferation

PSG8 PSG1 PSG9

9.67e-0627323GO:0070344
GeneOntologyBiologicalProcessnegative regulation of homotypic cell-cell adhesion

PSG8 PSG1 PSG9

1.08e-0528323GO:0034111
GeneOntologyBiologicalProcessregulation of vasculogenesis

PSG8 PSG1 PSG9

1.21e-0529323GO:2001212
GeneOntologyBiologicalProcessnegative regulation of platelet activation

PSG8 PSG1 PSG9

1.48e-0531323GO:0010544
GeneOntologyBiologicalProcessregulation of blood vessel remodeling

PSG8 PSG1 PSG9

1.63e-0532323GO:0060312
GeneOntologyBiologicalProcessnegative regulation of bone resorption

PSG8 PSG1 PSG9

1.63e-0532323GO:0045779
GeneOntologyBiologicalProcessfat cell proliferation

PSG8 PSG1 PSG9

1.63e-0532323GO:0070341
GeneOntologyBiologicalProcessnegative regulation of feeding behavior

PSG8 PSG1 PSG9

1.79e-0533323GO:2000252
GeneOntologyBiologicalProcessregulation of granulocyte differentiation

PSG8 PSG1 PSG9

1.79e-0533323GO:0030852
GeneOntologyBiologicalProcessnegative regulation of vascular permeability

PSG8 PSG1 PSG9

1.96e-0534323GO:0043116
GeneOntologyBiologicalProcessnegative regulation of bone remodeling

PSG8 PSG1 PSG9

1.96e-0534323GO:0046851
GeneOntologyBiologicalProcessinsulin metabolic process

PSG8 PSG1 PSG9

2.15e-0535323GO:1901142
GeneOntologyBiologicalProcessregulation of hepatocyte proliferation

PSG8 PSG1 PSG9

2.76e-0538323GO:2000345
GeneOntologyBiologicalProcessnegative regulation of fatty acid biosynthetic process

PSG8 PSG1 PSG9

2.98e-0539323GO:0045717
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity

PSG8 PSG1 PSG9

3.22e-0540323GO:0045953
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immunity

PSG8 PSG1 PSG9

3.47e-0541323GO:0002716
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

NKX3-2 ZNF750 DACT1 NCOR2 IRX6 BCL3 RESF1 BCOR IRX2 ZBTB4

3.53e-0514133210GO:1902679
GeneOntologyBiologicalProcessregulation of platelet aggregation

PSG8 PSG1 PSG9

3.74e-0542323GO:0090330
GeneOntologyBiologicalProcessnegative regulation of behavior

PSG8 PSG1 PSG9

4.60e-0545323GO:0048521
GeneOntologyBiologicalProcessepithelium development

NKX3-2 ZNF750 DACT1 NCOR2 PSG8 GCM2 PSG1 IRX2 PSG9 SOCS3

4.92e-0514693210GO:0060429
GeneOntologyBiologicalProcessepithelial cell proliferation involved in liver morphogenesis

PSG8 PSG1 PSG9

4.92e-0546323GO:0072575
GeneOntologyBiologicalProcesshepatocyte proliferation

PSG8 PSG1 PSG9

4.92e-0546323GO:0072574
GeneOntologyBiologicalProcessbile acid and bile salt transport

PSG8 PSG1 PSG9

5.25e-0547323GO:0015721
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated cytotoxicity

PSG8 PSG1 PSG9

5.25e-0547323GO:0001911
GeneOntologyBiologicalProcessnegative regulation of tissue remodeling

PSG8 PSG1 PSG9

5.25e-0547323GO:0034104
GeneOntologyBiologicalProcessliver morphogenesis

PSG8 PSG1 PSG9

5.95e-0549323GO:0072576
GeneOntologyBiologicalProcessregulation of immune response to tumor cell

PSG8 PSG1 PSG9

5.95e-0549323GO:0002837
GeneOntologyBiologicalProcessregulation of response to tumor cell

PSG8 PSG1 PSG9

6.33e-0550323GO:0002834
GeneOntologyBiologicalProcessnegative regulation of cell killing

PSG8 PSG1 PSG9

7.12e-0552323GO:0031342
GeneOntologyBiologicalProcessregulation of homotypic cell-cell adhesion

PSG8 PSG1 PSG9

7.54e-0553323GO:0034110
GeneOntologyBiologicalProcessimmune response to tumor cell

PSG8 PSG1 PSG9

8.89e-0556323GO:0002418
GeneOntologyBiologicalProcessanimal organ morphogenesis

ANKRD11 NKX3-2 NCOR2 PSG8 IRX6 BCOR PSG1 IRX2 PSG9

9.47e-051269329GO:0009887
GeneOntologyBiologicalProcessnegative regulation of osteoclast differentiation

PSG8 PSG1 PSG9

1.04e-0459323GO:0045671
GeneOntologyBiologicalProcessgranulocyte differentiation

PSG8 PSG1 PSG9

1.09e-0460323GO:0030851
GeneOntologyBiologicalProcessnegative regulation of fatty acid metabolic process

PSG8 PSG1 PSG9

1.09e-0460323GO:0045922
GeneOntologyBiologicalProcessregulation of feeding behavior

PSG8 PSG1 PSG9

1.15e-0461323GO:0060259
GeneOntologyBiologicalProcessregulation of platelet activation

PSG8 PSG1 PSG9

1.45e-0466323GO:0010543
GeneOntologyBiologicalProcessregulation of endothelial cell differentiation

PSG8 PSG1 PSG9

1.52e-0467323GO:0045601
GeneOntologyBiologicalProcessnegative regulation of blood coagulation

PSG8 PSG1 PSG9

1.66e-0469323GO:0030195
GeneOntologyBiologicalProcessregulation of bone resorption

PSG8 PSG1 PSG9

1.73e-0470323GO:0045124
GeneOntologyBiologicalProcessnegative regulation of hemostasis

PSG8 PSG1 PSG9

1.73e-0470323GO:1900047
GeneOntologyBiologicalProcessregulation of vascular permeability

PSG8 PSG1 PSG9

1.80e-0471323GO:0043114
GeneOntologyBiologicalProcessresponse to tumor cell

PSG8 PSG1 PSG9

1.80e-0471323GO:0002347
GeneOntologyBiologicalProcessnegative regulation of interleukin-1 production

PSG8 PSG1 PSG9

1.88e-0472323GO:0032692
GeneOntologyBiologicalProcessnegative regulation of coagulation

PSG8 PSG1 PSG9

1.88e-0472323GO:0050819
GeneOntologyBiologicalProcessregulation of fatty acid biosynthetic process

PSG8 PSG1 PSG9

1.96e-0473323GO:0042304
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

NKX3-2 ZNF750 DACT1 NCOR2 IRX6 BCL3 BCOR IRX2 ZBTB4

1.99e-041399329GO:0045892
GeneOntologyBiologicalProcessregulation of ketone metabolic process

NCOR2 PSG8 PSG1 PSG9

2.01e-04189324GO:0010565
GeneOntologyBiologicalProcessregulation of natural killer cell mediated cytotoxicity

PSG8 PSG1 PSG9

2.21e-0476323GO:0042269
GeneOntologyBiologicalProcessregulation of bone remodeling

PSG8 PSG1 PSG9

2.57e-0480323GO:0046850
GeneOntologyBiologicalProcessregulation of natural killer cell mediated immunity

PSG8 PSG1 PSG9

2.57e-0480323GO:0002715
GeneOntologyBiologicalProcessnegative regulation of protein phosphorylation

KIRREL1 PSG8 PSG1 PSG9 SOCS3

2.60e-04375325GO:0001933
GeneOntologyBiologicalProcessnegative regulation of lymphocyte mediated immunity

PSG8 PSG1 PSG9

2.86e-0483323GO:0002707
GeneOntologyBiologicalProcessregulation of sprouting angiogenesis

PSG8 PSG1 PSG9

3.07e-0485323GO:1903670
GeneOntologyBiologicalProcessnegative regulation of myeloid leukocyte differentiation

PSG8 PSG1 PSG9

3.07e-0485323GO:0002762
GeneOntologyBiologicalProcessregulation of epidermal growth factor receptor signaling pathway

PSG8 PSG1 PSG9

3.18e-0486323GO:0042058
GeneOntologyBiologicalProcessblood vessel remodeling

PSG8 PSG1 PSG9

3.29e-0487323GO:0001974
GeneOntologyBiologicalProcessnegative regulation of phosphorylation

KIRREL1 PSG8 PSG1 PSG9 SOCS3

3.54e-04401325GO:0042326
GeneOntologyBiologicalProcessnegative regulation of lipid biosynthetic process

PSG8 PSG1 PSG9

3.76e-0491323GO:0051055
GeneOntologyBiologicalProcessregulation of blood coagulation

PSG8 PSG1 PSG9

3.76e-0491323GO:0030193
GeneOntologyBiologicalProcesschordate embryonic development

ANKRD11 NKX3-2 DACT1 NCOR2 RBM46 BCOR SOCS3

3.96e-04906327GO:0043009
GeneOntologyBiologicalProcessregulation of hemostasis

PSG8 PSG1 PSG9

4.00e-0493323GO:1900046
GeneOntologyBiologicalProcessregulation of ERBB signaling pathway

PSG8 PSG1 PSG9

4.00e-0493323GO:1901184
GeneOntologyBiologicalProcessplatelet aggregation

PSG8 PSG1 PSG9

4.26e-0495323GO:0070527
GeneOntologyBiologicalProcesshemopoiesis

BRPF3 PSG8 BCL3 BRD1 PSG1 PSG9 PYGO1 SOCS3

4.37e-041223328GO:0030097
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated immunity

PSG8 PSG1 PSG9

4.39e-0496323GO:0002704
GeneOntologyBiologicalProcessregulation of coagulation

PSG8 PSG1 PSG9

4.39e-0496323GO:0050818
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

ANKRD11 NKX3-2 DACT1 NCOR2 RBM46 BCOR SOCS3

4.60e-04929327GO:0009792
GeneOntologyBiologicalProcessnegative regulation of wound healing

PSG8 PSG1 PSG9

4.67e-0498323GO:0061045
GeneOntologyBiologicalProcessbone resorption

PSG8 PSG1 PSG9

4.81e-0499323GO:0045453
GeneOntologyBiologicalProcessregulation of lipid biosynthetic process

ZNF750 PSG8 PSG1 PSG9

5.46e-04246324GO:0046890
GeneOntologyBiologicalProcesscell-cell junction organization

KIRREL1 PSG8 PSG1 PSG9

5.46e-04246324GO:0045216
GeneOntologyBiologicalProcessnatural killer cell mediated cytotoxicity

PSG8 PSG1 PSG9

5.71e-04105323GO:0042267
GeneOntologyBiologicalProcessnegative regulation of T cell proliferation

PSG8 PSG1 PSG9

6.03e-04107323GO:0042130
GeneOntologyBiologicalProcessnatural killer cell mediated immunity

PSG8 PSG1 PSG9

6.37e-04109323GO:0002228
GeneOntologyBiologicalProcessnegative regulation of innate immune response

PSG8 PSG1 PSG9

7.26e-04114323GO:0045824
GeneOntologyBiologicalProcessregulation of osteoclast differentiation

PSG8 PSG1 PSG9

7.63e-04116323GO:0045670
GeneOntologyBiologicalProcesscellular response to hormone stimulus

NCOR2 PSG8 TRIM68 PSG1 PSG9 SOCS3

7.77e-04727326GO:0032870
GeneOntologyCellularComponenttransforming growth factor beta ligand-receptor complex

PSG8 PSG1 PSG9

1.98e-0616333GO:0070021
GeneOntologyCellularComponentMOZ/MORF histone acetyltransferase complex

BRPF3 BRD1

5.05e-057332GO:0070776
GeneOntologyCellularComponentH3 histone acetyltransferase complex

BRPF3 BRD1

6.73e-058332GO:0070775
GeneOntologyCellularComponentchromatin

ANKRD11 NKX3-2 NCOR2 BRPF3 IRX6 BRD1 GCM2 IRX2 BARHL1

3.55e-041480339GO:0000785
GeneOntologyCellularComponentlateral plasma membrane

PSG8 PSG1 PSG9

3.83e-0490333GO:0016328
GeneOntologyCellularComponentciliary membrane

PSG8 PSG1 PSG9

4.92e-0498333GO:0060170
GeneOntologyCellularComponentcell projection membrane

KIRREL1 PSG8 EPS8L1 PSG1 PSG9

5.37e-04431335GO:0031253
GeneOntologyCellularComponenttransferase complex

BRPF3 PSG8 BRD1 BCOR PSG1 PSG9 SOCS3

6.43e-04963337GO:1990234
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

PSG8 PSG1 PSG9 SOCS3

1.84e-03335334GO:0061695
GeneOntologyCellularComponentserine/threonine protein kinase complex

PSG8 PSG1 PSG9

1.92e-03157333GO:1902554
GeneOntologyCellularComponentT cell receptor complex

PSG8 PSG1 PSG9

2.14e-03163333GO:0042101
GeneOntologyCellularComponentprotein kinase complex

PSG8 PSG1 PSG9

2.41e-03170333GO:1902911
GeneOntologyCellularComponentadherens junction

PSG8 PSG1 PSG9

4.48e-03212333GO:0005912
GeneOntologyCellularComponenthistone acetyltransferase complex

BRPF3 BRD1

9.65e-0394332GO:0000123
MousePhenodecreased carbon dioxide production

NCOR2 PSG8 PSG1 PSG9

4.52e-0731294MP:0008964
MousePhenodecreased susceptibility to Coronaviridae infection induced morbidity/mortality

PSG8 PSG1 PSG9

5.35e-0617293MP:0031047
MousePhenoabnormal circulating leptin level

ANKRD11 NCOR2 PSG8 PSG1 PSG9 SOCS3

7.45e-06236296MP:0005667
MousePhenoincreased skeletal muscle triglyceride level

PSG8 PSG1 PSG9

1.04e-0521293MP:0031415
MousePhenoabnormal carbon dioxide production

NCOR2 PSG8 PSG1 PSG9

1.05e-0567294MP:0008962
MousePhenodecreased fatty acid oxidation

PSG8 PSG1 PSG9

1.58e-0524293MP:0014172
MousePhenodecreased oxygen consumption

NCOR2 PSG8 PSG1 PSG9

2.02e-0579294MP:0005290
MousePhenoincreased abdominal fat pad weight

PSG8 PSG1 PSG9

2.27e-0527293MP:0009286
MousePhenodecreased susceptibility to Coronaviridae infection

PSG8 PSG1 PSG9

2.54e-0528293MP:0020950
MousePhenoabnormal skeletal muscle triglyceride level

PSG8 PSG1 PSG9

3.47e-0531293MP:0031413
MousePhenodecreased skeletal muscle cell glucose uptake

PSG8 PSG1 PSG9

5.02e-0535293MP:0031618
MousePhenoabnormal muscle triglyceride level

PSG8 PSG1 PSG9

5.47e-0536293MP:0031412
MousePhenodecreased muscle cell glucose uptake

PSG8 PSG1 PSG9

6.98e-0539293MP:0030022
MousePhenodecreased susceptibility to Riboviria infection induced morbidity/mortality

PSG8 PSG1 PSG9

1.00e-0444293MP:0031023
MousePhenodecreased energy expenditure

NCOR2 PSG8 PSG1 PSG9

1.01e-04119294MP:0004890
MousePhenoabnormal skeletal muscle cell glucose uptake

PSG8 PSG1 PSG9

1.22e-0447293MP:0031617
MousePhenoabnormal susceptibility to Coronaviridae infection

PSG8 PSG1 PSG9

1.39e-0449293MP:0020948
MousePhenodecreased cellular glucose uptake

PSG8 PSG1 PSG9

1.75e-0453293MP:0003926
MousePhenoabnormal fatty acid oxidation

PSG8 PSG1 PSG9

1.85e-0454293MP:0010953
MousePhenodecreased susceptibility to viral infection induced morbidity/mortality

PSG8 PSG1 PSG9

2.54e-0460293MP:0009790
MousePhenoabnormal colon morphology

DACT1 PSG8 PSG1 PSG9

2.58e-04152294MP:0000495
MousePhenoabnormal lipid oxidation

PSG8 PSG1 PSG9

2.66e-0461293MP:0010951
MousePhenoincreased insulin secretion

PSG8 PSG1 PSG9

3.07e-0464293MP:0003058
MousePhenoabnormal muscle cell glucose uptake

PSG8 PSG1 PSG9

3.52e-0467293MP:0004130
MousePhenoabnormal energy expenditure

NCOR2 PSG8 PSG1 PSG9 SOCS3

4.16e-04313295MP:0005450
MousePhenoabnormal vascular wound healing

PSG8 PSG1 PSG9

4.53e-0473293MP:0004883
MousePhenoabnormal energy homeostasis

NCOR2 PSG8 PSG1 PSG9 SOCS3

4.74e-04322295MP:0005448
MousePhenopolyphagia

PSG8 PSG1 PSG9

5.92e-0480293MP:0001433
MousePhenodecreased susceptibility to Riboviria infection

PSG8 PSG1 PSG9

6.37e-0482293MP:0020914
MousePhenoabnormal oxygen consumption

NCOR2 PSG8 PSG1 PSG9

6.64e-04195294MP:0005288
MousePhenoinsulin resistance

NCOR2 PSG8 PSG1 PSG9

6.89e-04197294MP:0005331
MousePhenoabnormal cellular glucose uptake

PSG8 PSG1 PSG9

1.20e-03102293MP:0003925
MousePhenodecreased respiratory quotient

PSG8 PSG1 PSG9

1.49e-03110293MP:0010379
DomainIRO

IRX6 IRX2

4.25e-056322SM00548
DomainIroquois_homeo

IRX6 IRX2

4.25e-056322IPR003893
DomainEnhancer_polycomb-like_N

BRPF3 BRD1

7.91e-058322IPR019542
DomainEPL1

BRPF3 BRD1

7.91e-058322PF10513
Domain-

NKX3-2 NCOR2 IRX6 IRX2 BARHL1

1.11e-042833251.10.10.60
DomainZnf_FYVE_PHD

BRPF3 BRD1 ZBTB4 PYGO1

1.12e-04147324IPR011011
DomainZinc_finger_PHD-type_CS

BRPF3 BRD1 PYGO1

1.86e-0465323IPR019786
DomainHomeodomain-like

NKX3-2 NCOR2 IRX6 IRX2 BARHL1

2.34e-04332325IPR009057
DomainIg_2

PSG8 PSG1 PSG9

2.62e-0473323PF13895
DomainV-set

KIRREL1 PSG8 PSG1 PSG9

2.64e-04184324PF07686
DomainHomeobox_CS

NKX3-2 IRX6 IRX2 BARHL1

2.75e-04186324IPR017970
DomainPHD

BRPF3 BRD1 PYGO1

2.84e-0475323PF00628
DomainZnf_PHD-finger

BRPF3 BRD1 PYGO1

3.31e-0479323IPR019787
DomainIg_V-set

KIRREL1 PSG8 PSG1 PSG9

3.56e-04199324IPR013106
DomainHomeobox_KN

IRX6 IRX2

3.81e-0417322PF05920
DomainHomeobox_KN_domain

IRX6 IRX2

3.81e-0417322IPR008422
DomainPHD

BRPF3 BRD1 PYGO1

4.69e-0489323SM00249
DomainZnf_PHD

BRPF3 BRD1 PYGO1

5.01e-0491323IPR001965
DomainPWWP

BRPF3 BRD1

5.30e-0420322SM00293
DomainZF_PHD_2

BRPF3 BRD1 PYGO1

5.68e-0495323PS50016
DomainZF_PHD_1

BRPF3 BRD1 PYGO1

5.86e-0496323PS01359
DomainEPHD

BRPF3 BRD1

6.43e-0422322PS51805
DomainHomeobox

NKX3-2 IRX6 IRX2 BARHL1

6.56e-04234324PF00046
DomainIGc2

KIRREL1 PSG8 PSG1 PSG9

6.66e-04235324SM00408
DomainIg_sub2

KIRREL1 PSG8 PSG1 PSG9

6.66e-04235324IPR003598
DomainHOMEOBOX_1

NKX3-2 IRX6 IRX2 BARHL1

6.77e-04236324PS00027
DomainHOX

NKX3-2 IRX6 IRX2 BARHL1

6.88e-04237324SM00389
DomainPWWP

BRPF3 BRD1

7.04e-0423322PF00855
DomainPWWP_dom

BRPF3 BRD1

7.04e-0423322IPR000313
DomainHomeobox_dom

NKX3-2 IRX6 IRX2 BARHL1

7.10e-04239324IPR001356
DomainHOMEOBOX_2

NKX3-2 IRX6 IRX2 BARHL1

7.10e-04239324PS50071
DomainPWWP

BRPF3 BRD1

7.67e-0424322PS50812
DomainBromodomain_CS

BRPF3 BRD1

9.01e-0426322IPR018359
DomainBROMODOMAIN_1

BRPF3 BRD1

1.82e-0337322PS00633
DomainSOCS_box

TULP4 SOCS3

1.92e-0338322PF07525
DomainBromodomain

BRPF3 BRD1

1.92e-0338322PF00439
DomainSOCS

TULP4 SOCS3

2.03e-0339322PS50225
DomainSOCS_box

TULP4 SOCS3

2.03e-0339322SM00969
DomainSOCS_box

TULP4 SOCS3

2.03e-0339322IPR001496
DomainBROMODOMAIN_2

BRPF3 BRD1

2.24e-0341322PS50014
DomainBROMO

BRPF3 BRD1

2.35e-0342322SM00297
DomainBromodomain

BRPF3 BRD1

2.35e-0342322IPR001487
Domain-

BRPF3 BRD1

2.35e-03423221.20.920.10
Domainig

PSG8 PSG1 PSG9

4.14e-03190323PF00047
DomainImmunoglobulin

PSG8 PSG1 PSG9

4.14e-03190323IPR013151
DomainIG

KIRREL1 PSG8 PSG1 PSG9

5.55e-03421324SM00409
DomainIg_sub

KIRREL1 PSG8 PSG1 PSG9

5.55e-03421324IPR003599
DomainAnk_2

ANKRD11 BCL3 BCOR

5.83e-03215323PF12796
DomainHTH_motif

NKX3-2 BARHL1

6.21e-0369322IPR000047
DomainAnk

ANKRD11 BCL3 BCOR

6.86e-03228323PF00023
Domain-

BRPF3 TRIM68 BRD1 PYGO1

6.96e-034493243.30.40.10
DomainZnf_RING/FYVE/PHD

BRPF3 TRIM68 BRD1 PYGO1

7.51e-03459324IPR013083
Domain-

ANKRD11 BCL3 BCOR

8.64e-032483231.25.40.20
DomainANK

ANKRD11 BCL3 BCOR

8.92e-03251323SM00248
DomainANK_REPEAT

ANKRD11 BCL3 BCOR

9.12e-03253323PS50088
DomainAnkyrin_rpt-contain_dom

ANKRD11 BCL3 BCOR

9.22e-03254323IPR020683
DomainANK_REP_REGION

ANKRD11 BCL3 BCOR

9.22e-03254323PS50297
DomainIG_LIKE

KIRREL1 PSG8 PSG1 PSG9

9.47e-03491324PS50835
DomainAnkyrin_rpt

ANKRD11 BCL3 BCOR

1.00e-02262323IPR002110
DomainIg-like_dom

KIRREL1 PSG8 PSG1 PSG9

1.03e-02503324IPR007110
DomainHomeobox_metazoa

NKX3-2 BARHL1

1.04e-0290322IPR020479
PathwayWP_EGFR1_SIGNALING_PATHWAY

PSG8 PSG1 PSG9 SOCS3

1.86e-04188224MM15828
PathwayREACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS

PSG8 PSG1 PSG9

4.70e-0499223MM14624
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

BRPF3 BRD1

9.20e-0429222MM15340
PathwayWP_1Q211_COPY_NUMBER_VARIATION_SYNDROME

KIRREL1 PYGO1

9.20e-0429222M39890
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

BRPF3 BRD1

9.85e-0430222M27637
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ANKRD11 C15orf39 DACT1 NCOR2 TNRC18 TULP4 SBF2 ZBTB4 SOCS3 SEC16A

4.79e-081105331035748872
Pubmed

Differential effects of prenatal stress on metabolic programming in diet-induced obese and dietary-resistant rats.

PSG8 PSG1 PSG9

2.21e-071333326219866
Pubmed

Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1.

PSG8 PSG1 PSG9

2.21e-071333334058224
Pubmed

A mouse carcinoembryonic antigen gene family member is a calcium-dependent cell adhesion molecule.

PSG8 PSG1 PSG9

2.21e-07133331985902
Pubmed

Amino acid substitutions and an insertion in the spike glycoprotein extend the host range of the murine coronavirus MHV-A59.

PSG8 PSG1 PSG9

2.21e-071333315207636
Pubmed

Characterization and transcriptional activity of the mouse biliary glycoprotein 1 gene, a carcinoembryonic antigen-related gene.

PSG8 PSG1 PSG9

2.21e-07133337628460
Pubmed

Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture.

PSG8 PSG1 PSG9

2.21e-071333319285068
Pubmed

Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice.

PSG8 PSG1 PSG9

2.21e-071333325724769
Pubmed

The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/- Mice.

PSG8 PSG1 PSG9

2.21e-071333318003729
Pubmed

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.

PSG8 PSG1 PSG9

2.21e-071333321760897
Pubmed

Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue.

PSG8 PSG1 PSG9

2.21e-071333326284027
Pubmed

Spatiotemporal expression of murine carcinoembryonic antigen (CEA) gene family members during mouse embryogenesis.

PSG8 PSG1 PSG9

2.21e-07133332133556
Pubmed

CEACAM1 regulates CD8+ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis.

PSG8 PSG1 PSG9

2.21e-071333332521208
Pubmed

High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion.

PSG8 PSG1 PSG9

2.21e-071333326374765
Pubmed

Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV.

PSG8 PSG1 PSG9

2.21e-07133331719235
Pubmed

CEACAM1 specifically suppresses B cell receptor signaling-mediated activation.

PSG8 PSG1 PSG9

2.21e-071333333352461
Pubmed

Targeted disruption of carcinoembryonic antigen-related cell adhesion molecule 1 promotes diet-induced hepatic steatosis and insulin resistance.

PSG8 PSG1 PSG9

2.21e-071333319406938
Pubmed

Down-regulation of Bgp1(a) viral receptor by interferon-gamma is related to the antiviral state and resistance to mouse hepatitis virus 3 infection.

PSG8 PSG1 PSG9

2.21e-071333310964771
Pubmed

Loss of CEACAM1 in hepatocytes causes hepatic fibrosis.

PSG8 PSG1 PSG9

2.21e-071333338381498
Pubmed

Neutrophil Extracellular Trap-Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma.

PSG8 PSG1 PSG9

2.21e-071333332169849
Pubmed

Murine coronavirus receptors are differentially expressed in the central nervous system and play virus strain-dependent roles in neuronal spread.

PSG8 PSG1 PSG9

2.21e-071333320739537
Pubmed

CEACAM1+ myeloid cells control angiogenesis in inflammation.

PSG8 PSG1 PSG9

2.21e-071333319273835
Pubmed

Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1.

PSG8 PSG1 PSG9

2.21e-071333319621080
Pubmed

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance.

PSG8 PSG1 PSG9

2.21e-071333325972571
Pubmed

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.

PSG8 PSG1 PSG9

2.21e-071333329967450
Pubmed

Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.

PSG8 PSG1 PSG9

2.21e-071333316638824
Pubmed

Mouse hepatitis virus utilizes two carcinoembryonic antigens as alternative receptors.

PSG8 PSG1 PSG9

2.21e-07133331326665
Pubmed

Decreased osteoclastogenesis and high bone mass in mice with impaired insulin clearance due to liver-specific inactivation to CEACAM1.

PSG8 PSG1 PSG9

2.21e-071333320044046
Pubmed

mmCGM1a: a mouse carcinoembryonic antigen gene family member, generated by alternative splicing, functions as an adhesion molecule.

PSG8 PSG1 PSG9

2.21e-07133331633107
Pubmed

Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.

PSG8 PSG1 PSG9

2.21e-071333332150576
Pubmed

CEACAM1: a key regulator of vascular permeability.

PSG8 PSG1 PSG9

2.21e-071333321081647
Pubmed

Pregnancy-specific glycoprotein (PSG) in baboon (Papio hamadryas): family size, domain structure, and prediction of a functional region in primate PSGs.

PSG8 PSG1 PSG9

2.21e-071333311133662
Pubmed

Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation.

PSG8 PSG1 PSG9

2.21e-071333339168268
Pubmed

Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.

PSG8 PSG1 PSG9

2.21e-071333322469976
Pubmed

Targeted disruption of the Ceacam1 (MHVR) gene leads to reduced susceptibility of mice to mouse hepatitis virus infection.

PSG8 PSG1 PSG9

2.21e-071333311483763
Pubmed

Expression of newly identified secretory CEACAM1(a) isoforms in the intestinal epithelium.

PSG8 PSG1 PSG9

2.21e-071333319358828
Pubmed

Mouse hepatitis virus type 4 (JHM strains). induced fatal central nervous system disease. I. genetic control and murine neuron as the susceptible site of disease.

PSG8 PSG1 PSG9

2.21e-07133336265583
Pubmed

CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation.

PSG8 PSG1 PSG9

2.21e-071333321532628
Pubmed

The role of CEA-related cell adhesion molecule-1 (CEACAM1) in vascular homeostasis.

PSG8 PSG1 PSG9

2.21e-071333327695943
Pubmed

Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor.

PSG8 PSG1 PSG9

2.21e-071333328035001
Pubmed

Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1.

PSG8 PSG1 PSG9

2.21e-071333334440862
Pubmed

CEACAM1 is a potent regulator of B cell receptor complex-induced activation.

PSG8 PSG1 PSG9

2.21e-071333312832451
Pubmed

CEACAM1 confers resistance toward oxygen-induced vessel damage in a mouse model of retinopathy of prematurity.

PSG8 PSG1 PSG9

2.21e-071333325406283
Pubmed

Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.

PSG8 PSG1 PSG9

2.21e-071333315316023
Pubmed

The expression of mouse biliary glycoprotein, a carcinoembryonic antigen-related gene, is down-regulated in malignant mouse tissues.

PSG8 PSG1 PSG9

2.21e-07133338402684
Pubmed

Generation of human CEACAM1 transgenic mice and binding of Neisseria Opa protein to their neutrophils.

PSG8 PSG1 PSG9

2.21e-071333320404914
Pubmed

CEACAM1 deficiency delays important wound healing processes.

PSG8 PSG1 PSG9

2.21e-071333322092845
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo.

PSG8 PSG1 PSG9

2.21e-071333316680193
Pubmed

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor.

PSG8 PSG1 PSG9

2.21e-071333321670291
Pubmed

Investigations on the usefulness of CEACAMs as potential imaging targets for molecular imaging purposes.

PSG8 PSG1 PSG9

2.21e-071333322162753
Pubmed

Activation-induced expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse T lymphocyte function.

PSG8 PSG1 PSG9

2.21e-071333311801635
Pubmed

Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice.

PSG8 PSG1 PSG9

2.21e-07133332164599
Pubmed

Loss of CEACAM1, a Tumor-Associated Factor, Attenuates Post-infarction Cardiac Remodeling by Inhibiting Apoptosis.

PSG8 PSG1 PSG9

2.21e-071333326911181
Pubmed

The mouse biliary glycoprotein gene (Bgp): partial nucleotide sequence, expression, and chromosomal assignment.

PSG8 PSG1 PSG9

2.21e-07133331653760
Pubmed

In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa.

PSG8 PSG1 PSG9

2.21e-071333323935487
Pubmed

A mouse analogue of the human carcinoembryonic antigen.

PSG8 PSG1 PSG9

2.21e-07133332702644
Pubmed

Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice.

PSG8 PSG1 PSG9

2.21e-071333328913658
Pubmed

Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis.

PSG8 PSG1 PSG9

2.21e-071333316619040
Pubmed

Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury.

PSG8 PSG1 PSG9

2.21e-071333332027621
Pubmed

CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo.

PSG8 PSG1 PSG9

2.21e-071333319008452
Pubmed

Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59.

PSG8 PSG1 PSG9

2.21e-07133338380065
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

PSG8 PSG1 PSG9

2.21e-071333318544705
Pubmed

The receptor for mouse hepatitis virus in the resistant mouse strain SJL is functional: implications for the requirement of a second factor for viral infection.

PSG8 PSG1 PSG9

2.21e-07133331279194
Pubmed

Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis.

PSG8 PSG1 PSG9

2.21e-071333330664851
Pubmed

Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis.

PSG8 PSG1 PSG9

2.21e-071333327777319
Pubmed

Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59.

PSG8 PSG1 PSG9

2.21e-071333315331748
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice.

PSG8 PSG1 PSG9

2.21e-071333329377208
Pubmed

Expression of the mouse hepatitis virus receptor by central nervous system microglia.

PSG8 PSG1 PSG9

2.21e-071333315220458
Pubmed

Expression of MHV-A59 receptor glycoproteins in susceptible and resistant strains of mice.

PSG8 PSG1 PSG9

2.21e-07133338209741
Pubmed

Organ tropism of murine coronavirus does not correlate with the expression levels of the membrane-anchored or secreted isoforms of the carcinoembryonic antigen-related cell adhesion molecule 1 receptor.

PSG8 PSG1 PSG9

2.21e-071333322673933
Pubmed

Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1.

PSG8 PSG1 PSG9

2.21e-071333322406619
Pubmed

Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice.

PSG8 PSG1 PSG9

2.21e-071333318848945
Pubmed

Expression of the Bgp gene and characterization of mouse colon biliary glycoprotein isoforms.

PSG8 PSG1 PSG9

2.21e-07133338500759
Pubmed

Leptin Resistance Contributes to Obesity in Mice with Null Mutation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 1.

PSG8 PSG1 PSG9

2.21e-071333327002145
Pubmed

Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.

PSG8 PSG1 PSG9

2.21e-071333321949477
Pubmed

Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils.

PSG8 PSG1 PSG9

2.21e-071333318843289
Pubmed

Mouse susceptibility to mouse hepatitis virus infection is linked to viral receptor genotype.

PSG8 PSG1 PSG9

2.21e-07133339343248
Pubmed

Ceacam1 deletion causes vascular alterations in large vessels.

PSG8 PSG1 PSG9

2.21e-071333323800882
Pubmed

Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene.

PSG8 PSG1 PSG9

2.21e-071333329396368
Pubmed

Alternative splicing of CEACAM1 by hypoxia-inducible factor-1α enhances tolerance to hepatic ischemia in mice and humans.

PSG8 PSG1 PSG9

2.81e-071433337531413
Pubmed

CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium.

PSG8 PSG1 PSG9

2.81e-071433318794798
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke.

PSG8 PSG1 PSG9

2.81e-071433323780386
Pubmed

Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene.

PSG8 PSG1 PSG9

2.81e-071433328567513
Pubmed

CEACAM-1 promotes myocardial injury following coxsackievirus infection by regulating the coxsackievirus-adenovirus receptor.

PSG8 PSG1 PSG9

2.81e-071433331083261
Pubmed

Bgp2, a new member of the carcinoembryonic antigen-related gene family, encodes an alternative receptor for mouse hepatitis viruses.

PSG8 PSG1 PSG9

2.81e-07143338207827
Pubmed

Protein kinase Cε modulates insulin receptor localization and trafficking in mouse embryonic fibroblasts.

PSG8 PSG1 PSG9

2.81e-071433323469261
Pubmed

Intestinal tumor progression is promoted by decreased apoptosis and dysregulated Wnt signaling in Ceacam1-/- mice.

PSG8 PSG1 PSG9

2.81e-071433318454175
Pubmed

Receptor for mouse hepatitis virus is a member of the carcinoembryonic antigen family of glycoproteins.

PSG8 PSG1 PSG9

2.81e-07143331648219
Pubmed

CEACAM1 regulates integrin αIIbβ3-mediated functions in platelets.

PSG8 PSG1 PSG9

2.81e-071433326196244
Pubmed

Comparison of expression patterns and cell adhesion properties of the mouse biliary glycoproteins Bbgp1 and Bbgp2.

PSG8 PSG1 PSG9

2.81e-071433310491101
Pubmed

SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms.

PSG8 PSG1 PSG9

2.81e-071433317081782
Pubmed

Human CEACAM1-LF regulates lipid storage in HepG2 cells via fatty acid transporter CD36.

PSG8 PSG1 PSG9

2.81e-071433334666041
Pubmed

Biliary glycoprotein 1 expression during embryogenesis: correlation with events of epithelial differentiation, mesenchymal-epithelial interactions, absorption, and myogenesis.

PSG8 PSG1 PSG9

2.81e-07143338896983
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 modulates experimental autoimmune encephalomyelitis via an iNKT cell-dependent mechanism.

PSG8 PSG1 PSG9

2.81e-071433319700760
Pubmed

Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2.

PSG8 PSG1 PSG9

2.81e-071433322159884
Pubmed

Mice Lacking PECAM-1 and Ceacam1 Have Enhanced Platelet Secretion and Thrombus Growth: Novel Link with PAR4.

PSG8 PSG1 PSG9

2.81e-071433334619794
Pubmed

NLRC5 deficiency protects against acute kidney injury in mice by mediating carcinoembryonic antigen-related cell adhesion molecule 1 signaling.

PSG8 PSG1 PSG9

2.81e-071433329907459
Pubmed

Loss of Ceacam1 promotes prostate cancer progression in Pten haploinsufficient male mice.

PSG8 PSG1 PSG9

2.81e-071433332209360
Pubmed

Acceleration of collateral development by carcinoembryonic antigen-related cell adhesion molecule 1 expression on CD11b/⁺Gr-1⁺ myeloid cells--brief report.

PSG8 PSG1 PSG9

2.81e-071433322962327
Pubmed

The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38.

PSG8 PSG1 PSG9

2.81e-071433317623671
InteractionSOX7 interactions

C15orf39 NCOR2 TNRC18 RESF1 BCOR

2.14e-0782335int:SOX7
InteractionEGR2 interactions

C15orf39 NCOR2 TNRC18 RESF1 BCOR SEC16A

3.13e-07171336int:EGR2
InteractionCTBP1 interactions

C15orf39 ZNF750 NCOR2 BCL3 RESF1 BCOR SEC16A

3.48e-06406337int:CTBP1
InteractionGUSBP5 interactions

C15orf39 NCOR2 TNRC18 BCOR

6.67e-0675334int:GUSBP5
InteractionRCOR1 interactions

C15orf39 ZNF750 NCOR2 BCL3 RESF1 BCOR SEC16A

1.25e-05494337int:RCOR1
InteractionFOLR3 interactions

ANKRD11 TRIM68

5.43e-057332int:FOLR3
InteractionCRX interactions

C15orf39 NCOR2 TNRC18 IRX6 GCM2

5.44e-05254335int:CRX
InteractionCELSR3 interactions

PSG8 PSG1 PSG9

5.79e-0546333int:CELSR3
InteractionPSG4 interactions

PSG8 PSG1

7.24e-058332int:PSG4
InteractionPSG1 interactions

PSG8 PSG1 PSG9

7.90e-0551333int:PSG1
InteractionTOP3B interactions

ANKRD11 C15orf39 DACT1 NCOR2 TNRC18 TULP4 SBF2 ZBTB4 SOCS3 SEC16A

8.08e-0514703310int:TOP3B
InteractionHDAC3 interactions

ANKRD11 NCOR2 BCL3 BCOR SEC16A

1.45e-04313335int:HDAC3
InteractionDTX2 interactions

C15orf39 KIRREL1 NCOR2 BCOR SEC16A

1.86e-04330335int:DTX2
InteractionALG13 interactions

C15orf39 NCOR2 BCOR SEC16A

2.19e-04183334int:ALG13
InteractionING4 interactions

BRPF3 BRD1 BCOR

2.80e-0478333int:ING4
InteractionHDAC1 interactions

NKX3-2 C15orf39 ZNF750 DACT1 NCOR2 TNRC18 BCL3 BCOR

3.29e-041108338int:HDAC1
InteractionTLE3 interactions

C15orf39 NCOR2 TNRC18 BCOR ZBTB4

3.40e-04376335int:TLE3
InteractionGSC interactions

C15orf39 NCOR2 TNRC18

3.86e-0487333int:GSC
InteractionERG interactions

C15orf39 NCOR2 RESF1 BCOR

4.64e-04223334int:ERG
InteractionTBX19 interactions

IRX6 GCM2

4.85e-0420332int:TBX19
CytobandEnsembl 112 genes in cytogenetic band chr19q13

PSG8 TMC4 EPS8L1 BCL3 PSG1 PSG9

1.84e-041192336chr19q13
Cytoband19q13.2

PSG8 PSG1 PSG9

2.26e-0416433319q13.2
Cytoband17q25.3

ZNF750 SOCS3

2.42e-0310133217q25.3
Cytoband19q13.42

TMC4 EPS8L1

3.67e-0312533219q13.42
Cytoband11p15.4

TRIM68 SBF2

9.12e-0320033211p15.4
GeneFamilyCD molecules|V-set domain containing|Pregnancy specific glycoproteins

PSG8 PSG1 PSG9

3.83e-07112531315
GeneFamilyPHD finger proteins

BRPF3 BRD1 PYGO1

2.53e-049025388
GeneFamilyPWWP domain containing

BRPF3 BRD1

4.17e-04222521147
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOR2 TNRC18

5.40e-0425252775
GeneFamilyTALE class homeoboxes and pseudogenes

IRX6 IRX2

5.85e-0426252526
GeneFamilyAdenosine receptors|V-set domain containing

PSG8 PSG1 PSG9

1.43e-03163253590
GeneFamilyNKL subclass homeoboxes and pseudogenes

NKX3-2 BARHL1

3.84e-0367252519
GeneFamilyAnkyrin repeat domain containing

ANKRD11 BCL3 BCOR

4.38e-03242253403
CoexpressionHOLLERN_EMT_BREAST_TUMOR_DN

PSG8 TMC4 EPS8L1 PSG1 PSG9

7.11e-07135335MM965
CoexpressionLIM_MAMMARY_STEM_CELL_DN

ZNF750 PSG8 TMC4 TRIM68 BCL3 PSG1 PSG9

9.87e-07436337MM1326
CoexpressionTGFB_UP.V1_UP

DACT1 NCOR2 BCOR TULP4 ZNF654

3.72e-06189335M2839
CoexpressionTABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_MYELOID_CELL_AGEING

PSG8 BCL3 PSG1 PSG9 SOCS3

7.63e-06219335MM3826
CoexpressionGIBBONS_GENETIC_MOUSE_MODEL_LUNG_ADENOCARCINOMA_DOWN_IN_METASTASIS

PSG8 PSG1 PSG9

8.80e-0632333MM2
CoexpressionOUYANG_PROSTATE_CANCER_MARKERS

PSG8 PSG1 PSG9

1.16e-0535333MM757
CoexpressionMARTIN_INTERACT_WITH_HDAC

ANKRD11 NCOR2 BCOR

1.88e-0541333M15154
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

NKX3-2 IRX6 BCL3 IRX2 BARHL1

2.17e-05272335M1938
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

NKX3-2 IRX6 BCL3 IRX2 BARHL1

2.58e-05282335MM822
CoexpressionWANG_RESPONSE_TO_BEXAROTENE_UP

PSG8 PSG1 PSG9

3.03e-0548333MM531
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_DN

PSG8 PSG1 PSG9 SOCS3

4.65e-05159334MM760
CoexpressionGSE16266_CTRL_VS_LPS_STIM_MEF_UP

NCOR2 BRPF3 BCOR ZBTB4

1.09e-04198334M7219
CoexpressionGSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_UP

KIRREL1 IRX6 BCL3 SOCS3

1.11e-04199334M7067
CoexpressionBYSTROEM_CORRELATED_WITH_IL5_DN

PSG8 PSG1 PSG9

1.15e-0475333MM605
CoexpressionTABULA_MURIS_SENIS_KIDNEY_KIDNEY_COLLECTING_DUCT_PRINCIPAL_CELL_AGEING

ANKRD11 TNRC18 TMC4 RESF1 SOCS3

1.26e-04394335MM3724
CoexpressionDESCARTES_FETAL_ADRENAL_CSH1_CSH2_POSITIVE_CELLS

PSG8 EPS8L1 PSG1 PSG9

1.75e-04224334M40145
CoexpressionBOYLAN_MULTIPLE_MYELOMA_PCA3_DN

PSG8 PSG1 PSG9

1.79e-0487333MM851
CoexpressionMCBRYAN_PUBERTAL_BREAST_3_4WK_UP

PSG8 PSG1 IRX2 PSG9

1.94e-04230334MM986
CoexpressionDESCARTES_FETAL_PLACENTA_TROPHOBLAST_GIANT_CELLS

PSG8 PSG1 PSG9

2.18e-0493333M40279
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_5

BCL3 SOCS3

2.32e-0418332M1388
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

NKX3-2 KIRREL1 DACT1 TMC4 BCL3 SOCS3

4.20e-04795336M39050
CoexpressionMCBRYAN_PUBERTAL_BREAST_4_5WK_UP

PSG8 PSG1 IRX2 PSG9

4.31e-04284334MM987
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#4_top-relative-expression-ranked_500

ZNF750 TMC4 EPS8L1 IRX2

4.12e-0670334gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#4_top-relative-expression-ranked_1000

ZNF750 TMC4 EPS8L1 IRX2

5.08e-05132334gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k4
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF750 EPS8L1 BCOR IRX2

1.29e-051963346e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF750 EPS8L1 BCOR IRX2

1.29e-05196334547901c7a665770eff78eede69b8625b416c8186
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZNF750 IRX6 BARHL1

1.32e-05623333eec7f31de7cc24762c5b180475650676437dc76
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZNF750 IRX6 BARHL1

1.32e-0562333f5f5441f5be00ab80a7827c4af1afbe45c552c2e
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZNF750 IRX6 BARHL1

1.32e-05623336e81a37b9defa96528654bee1b23152108d9c0b7
ComputationalNeighborhood of CDKN1C

PSG1 PSG9

7.13e-0427162GNF2_CDKN1C
ComputationalNeighborhood of TNFRSF25

BCL3 PSG1

8.82e-0430162CAR_TNFRSF25
ComputationalNeighborhood of EGFR

PSG1 PSG9

1.00e-0332162GNF2_EGFR
ComputationalNeighborhood of IGFBP1

PSG1 PSG9

1.20e-0335162GNF2_IGFBP1
ComputationalNeighborhood of MMP11

PSG1 PSG9

1.73e-0342162GNF2_MMP11
ComputationalNeighborhood of TIMP2

PSG1 PSG9

2.07e-0346162GNF2_TIMP2
ComputationalNeighborhood of KISS1

PSG1 PSG9

2.35e-0349162GNF2_KISS1
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

ANKRD11 RESF1

2.35e-0349162GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DrugPimozide [2062-78-4]; Up 200; 8.6uM; HL60; HG-U133A

ANKRD11 EPS8L1 TRIM68 BCL3 SOCS3

7.93e-061923351562_UP
DiseasecD177 antigen measurement

PSG8 PSG1 PSG9

9.35e-0718323EFO_0021866
DiseaseClear cell sarcoma of kidney

BCOR IRX2

1.70e-056322C0334488
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

NCOR2 BCL3 PSG1 SEC16A

1.26e-04239324EFO_0008317, EFO_0020945
Diseaseiritis

TNRC18 PSG1

1.53e-0417322EFO_1000997
Diseasehypospadias

IRX6 PSG1

8.23e-0439322EFO_0004209
Diseaseeosinophil count

ANKRD11 NCOR2 BCL3 RESF1 PSG1 SBF2 SEC16A

9.05e-041488327EFO_0004842
Diseasesexual dimorphism measurement

ANKRD11 NCOR2 BRPF3 BCL3 ZBTB4 SEC16A

1.07e-031106326EFO_0021796
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

NCOR2 BCL3 PSG1

1.82e-03224323EFO_0004574, EFO_0008317
DiseaseAtherogenesis

BCL3 SOCS3

1.88e-0359322C1563937
DiseaseAtherosclerosis

BCL3 SOCS3

1.88e-0359322C0004153
Diseasesquamous cell carcinoma

ANKRD11 SEC16A

2.41e-0367322EFO_0000707
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

NCOR2 BCL3 SBF2

3.29e-03276323EFO_0004612, EFO_0020943
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

NCOR2 BCL3 SBF2

4.27e-03303323EFO_0004612, EFO_0020945
Diseasemean fractional anisotropy measurement

ANKRD11 DACT1

4.78e-0395322EFO_0008399
Diseasebody surface area

ANKRD11 NCOR2 BRPF3 ZBTB4

4.95e-03643324EFO_0022196
DiseaseAdenoid Cystic Carcinoma

BRD1 BCOR

5.28e-03100322C0010606
DiseaseHypermetropia

ANKRD11 TULP4

5.59e-03103322HP_0000540
Diseaseremnant cholesterol measurement

BCL3 PSG1

6.13e-03108322EFO_0010815
Diseaselipoprotein A measurement

BCL3 TULP4

6.58e-03112322EFO_0006925
Diseaseviral load

TMC4 PSG1

9.55e-03136322EFO_0010125

Protein segments in the cluster

PeptideGeneStartEntry
EYSPPSAPRRPPVYY

BRD1

126

O95696
LSPGYYSPDYGLPSP

ANKRD11

1846

Q6UB99
ALYLYRGPSAPPPAL

BARHL1

276

Q9BZE3
IQPEAPPLPAAYYRY

BRPF3

126

Q9ULD4
PPLPAAYYRYIEKPP

BRPF3

131

Q9ULD4
FRSPPIPYPRSYLPY

BCOR

646

Q6W2J9
IPYPRSYLPYPAPEG

BCOR

651

Q6W2J9
IRPLTKIPPYHGPYY

ARMCX5

261

Q6P1M9
PSVLPYTSRPYSYPG

RBM46

491

Q8TBY0
YTSRPYSYPGYPLSP

RBM46

496

Q8TBY0
GYLPYSPEPPSLYGA

IRX6

86

P78412
YPHLYPPYLIRGYPD

NCOR2

1661

Q9Y618
FPLKYSYPYIPILPA

SBF2

246

Q86WG5
PYPASPLLGRPLYYT

IRX2

371

Q9BZI1
PYGIRNLPPPLYYRP

PRR27

41

Q6MZM9
PPSLLPLQPSYYYPY

NKX3-2

301

P78367
PAPVPLPYASPYAYV

DACT1

706

Q9NYF0
YPTYRLGYPQAPPSG

KIRREL1

701

Q96J84
YVPYNILTPYPGPRL

EPS8L1

526

Q8TE68
ALYYPGALLPLYPTR

BCL3

81

P20749
GPDLPRIYPSFTYYR

PSG1

331

P11464
YKPLPSSNPYLGPGY

PYGO1

81

Q9Y3Y4
LTYPDYRPPPKLYRY

RESF1

206

Q9HCM1
YRPPPKLYRYSPQSF

RESF1

211

Q9HCM1
GPDLPRIYPSFTYYR

PSG8

331

Q9UQ74
GPDLPRIYPSFTYYR

PSG9

331

Q00887
YSSPRIYLPRPPCSY

GCM2

261

O75603
QAPYIPPLGLDAYPY

C15orf39

331

Q6ZRI6
RYPFQALPPHYGRPY

TNRC18

1081

O15417
YPSNLPIPYGFYRPE

ZNF750

311

Q32MQ0
YPPSLSYCTLPPMYP

TULP4

1231

Q9NRJ4
RYPFPGRLLPYFSPC

TRIM68

451

Q6AZZ1
PPPQDLAAYYYYRPL

SEC16A

1151

O15027
WSPLFYGFYPPRPRL

TMC4

236

Q7Z404
YGFYPPRPRLAVTYL

TMC4

241

Q7Z404
PYVRPLPPSYLDERY

ZNF654

1046

Q8IZM8
PYPLVYGPQLLAAYP

ZBTB4

921

Q9P1Z0
LPGSPPRRAYYIYSG

SOCS3

156

O14543