Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase activity	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 F2 F12 PRSS42P PRSS45P TMPRSS7	4.71e-08	190	130	11	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 F2 F12 PRSS42P PRSS45P TMPRSS7	1.13e-07	207	130	11	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 F2 F12 PRSS42P PRSS45P TMPRSS7	1.44e-07	212	130	11	GO:0017171
GeneOntologyMolecularFunction	endopeptidase activity	TMPRSS15 PMPCB TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 HM13 F2 F12 PRSS42P PRSS45P TMPRSS7	4.77e-06	430	130	13	GO:0004175
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC43A2 SLC27A6 SPNS2 KCNAB2 COX15 SLC39A10 PKD1L2 SLC25A37 SLC39A13 CHRNB2 SLC7A9 CLCNKA CLCNKB SLC16A2 SLC25A39 KCNAB1 SLC25A11 TAP1 ATP2B1 KCNAB3 SLC38A8	2.43e-05	1180	130	21	GO:0022857
GeneOntologyMolecularFunction	transporter activity	SLC43A2 ATP8B4 SLC27A6 SPNS2 KCNAB2 COX15 SLC39A10 PKD1L2 SLC25A37 SLC39A13 CHRNB2 SLC7A9 CLCNKA CLCNKB SLC16A2 SLC25A39 KCNAB1 SLC25A11 TAP1 ATP2B1 KCNAB3 SLC38A8	2.88e-05	1289	130	22	GO:0005215
GeneOntologyMolecularFunction	peptidase activity	TMPRSS15 PMPCB TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 HM13 F2 F12 PRSS42P PRSS45P TMPRSS7	3.46e-04	654	130	13	GO:0008233
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	SLC43A2 SLC7A9 SLC25A39 SLC25A11	6.72e-04	61	130	4	GO:1901682
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC43A2 SLC27A6 SLC39A10 SLC7A9 SLC16A2 SLC25A39 SLC25A11 SLC38A8	6.77e-04	293	130	8	GO:0008514
MousePheno	abnormal lateral geniculate nucleus morphology	HCAR1 CHRNB2 SLC38A8	1.82e-05	8	98	3	MP:0004165
MousePheno	abnormal thalamus morphology	HCAR1 GRN CHRNB2 TRAPPC9 SLC38A8	3.68e-05	54	98	5	MP:0000832
Domain	Peptidase_S1_PA	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 COX15 PRSS33 TYSND1 F2 F12 PRSS42P PRSS45P TMPRSS7	4.81e-11	123	128	12	IPR009003
Domain	Tryp_SPc	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 F2 F12 PRSS42P PRSS45P TMPRSS7	4.76e-10	117	128	11	SM00020
Domain	Trypsin	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 F2 F12 PRSS42P PRSS45P TMPRSS7	6.84e-10	121	128	11	PF00089
Domain	Trypsin_dom	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 TYSND1 F2 F12 PRSS42P PRSS45P TMPRSS7	6.84e-10	121	128	11	IPR001254
Domain	TRYPSIN_HIS	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 F2 F12 PRSS42P PRSS45P TMPRSS7	2.21e-09	103	128	10	IPR018114
Domain	TRYPSIN_SER	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 F2 F12 PRSS42P PRSS45P TMPRSS7	2.93e-09	106	128	10	PS00135
Domain	TRYPSIN_HIS	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 F2 F12 PRSS42P PRSS45P TMPRSS7	3.21e-09	107	128	10	PS00134
Domain	Peptidase_S1A	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 F2 F12 PRSS42P PRSS45P TMPRSS7	5.48e-09	113	128	10	IPR001314
Domain	TRYPSIN_DOM	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 F2 F12 PRSS42P PRSS45P TMPRSS7	6.50e-09	115	128	10	PS50240
Domain	WD40	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	2.67e-08	259	128	13	PF00400
Domain	WD40	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	3.99e-08	268	128	13	SM00320
Domain	WD40_repeat	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	4.75e-08	272	128	13	IPR001680
Domain	WD_REPEATS_1	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	6.13e-08	278	128	13	PS00678
Domain	WD_REPEATS_2	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	6.39e-08	279	128	13	PS50082
Domain	WD_REPEATS_REGION	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	6.39e-08	279	128	13	PS50294
Domain	WD40_repeat_dom	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	1.32e-07	297	128	13	IPR017986
Domain	TRYPSIN_SER	TMPRSS15 TMPRSS6 CTRB2 TMPRSS12 PRSS33 F2 F12 TMPRSS7	1.89e-07	90	128	8	IPR033116
Domain	WD40_repeat_CS	AAMP PEX7 WDFY4 LYST WDR47 EML5 WDR11 TLE2 NLE1 WDFY3	1.93e-07	164	128	10	IPR019775
Domain	K_chnl_volt-dep_bsu_KCNAB-rel	KCNAB2 KCNAB1 KCNAB3	3.14e-07	3	128	3	IPR005399
Domain	K_chnl_volt-dep_bsu_KCNAB	KCNAB2 KCNAB1 KCNAB3	3.14e-07	3	128	3	IPR005983
Domain	-	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	4.89e-07	333	128	13	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	5.24e-07	335	128	13	IPR015943
Domain	PH-BEACH_dom	WDFY4 LYST WDFY3	1.72e-05	8	128	3	IPR023362
Domain	-	WDFY4 LYST WDFY3	1.72e-05	8	128	3	2.30.29.40
Domain	PH_BEACH	WDFY4 LYST WDFY3	1.72e-05	8	128	3	PS51783
Domain	CUB	TMPRSS15 TMPRSS6 CSMD2 CSMD3 TMPRSS7	2.31e-05	50	128	5	SM00042
Domain	BEACH_dom	WDFY4 LYST WDFY3	2.56e-05	9	128	3	IPR000409
Domain	BEACH	WDFY4 LYST WDFY3	2.56e-05	9	128	3	PS50197
Domain	Beach	WDFY4 LYST WDFY3	2.56e-05	9	128	3	PF02138
Domain	-	WDFY4 LYST WDFY3	2.56e-05	9	128	3	1.10.1540.10
Domain	Beach	WDFY4 LYST WDFY3	2.56e-05	9	128	3	SM01026
Domain	-	TMPRSS15 TMPRSS6 CSMD2 CSMD3 TMPRSS7	2.81e-05	52	128	5	2.60.120.290
Domain	CUB	TMPRSS15 TMPRSS6 CSMD2 CSMD3 TMPRSS7	3.08e-05	53	128	5	PS01180
Domain	CUB_dom	TMPRSS15 TMPRSS6 CSMD2 CSMD3 TMPRSS7	4.40e-05	57	128	5	IPR000859
Domain	Cl_channel-K	CLCNKA CLCNKB	4.66e-05	2	128	2	IPR002250
Domain	EamA_dom	SLC35G4 SLC35G3 SLC35G5	1.08e-04	14	128	3	IPR000620
Domain	EamA	SLC35G4 SLC35G3 SLC35G5	1.08e-04	14	128	3	PF00892
Domain	-	TMPRSS15 TMPRSS6 TMPRSS7	1.35e-04	15	128	3	3.30.70.960
Domain	Pellino	PELI3 PELI1	1.39e-04	3	128	2	PF04710
Domain	Pellino_fam	PELI3 PELI1	1.39e-04	3	128	2	IPR006800
Domain	-	KCNAB2 KCNAB1 KCNAB3	1.65e-04	16	128	3	3.20.20.100
Domain	NADP_OxRdtase_dom	KCNAB2 KCNAB1 KCNAB3	1.99e-04	17	128	3	IPR023210
Domain	Aldo_ket_red	KCNAB2 KCNAB1 KCNAB3	1.99e-04	17	128	3	PF00248
Domain	Aldo/ket_red/Kv-b	KCNAB2 KCNAB1 KCNAB3	1.99e-04	17	128	3	IPR001395
Domain	CUB	TMPRSS15 CSMD2 CSMD3 TMPRSS7	3.51e-04	49	128	4	PF00431
Domain	SRCR	TMPRSS15 CD163L1 LOXL3	3.82e-04	21	128	3	PF00530
Domain	SEA	TMPRSS15 TMPRSS6 TMPRSS7	4.40e-04	22	128	3	PF01390
Domain	Quinoprotein_ADH-like_supfam	AAMP WDR27 EML5 UTP4	4.75e-04	53	128	4	IPR011047
Domain	SEA	TMPRSS15 TMPRSS6 TMPRSS7	5.04e-04	23	128	3	PS50024
Domain	SEA_dom	TMPRSS15 TMPRSS6 TMPRSS7	5.04e-04	23	128	3	IPR000082
Domain	SR	TMPRSS15 CD163L1 LOXL3	6.48e-04	25	128	3	SM00202
Domain	-	TMPRSS15 CD163L1 LOXL3	6.48e-04	25	128	3	3.10.250.10
Domain	PH_BEACH	LYST WDFY3	6.87e-04	6	128	2	PF14844
Domain	SRCR_1	TMPRSS15 CD163L1 LOXL3	7.28e-04	26	128	3	PS00420
Domain	SRCR_2	TMPRSS15 CD163L1 LOXL3	7.28e-04	26	128	3	PS50287
Domain	SRCR-like_dom	TMPRSS15 CD163L1 LOXL3	7.28e-04	26	128	3	IPR017448
Domain	SRCR	TMPRSS15 CD163L1 LOXL3	8.15e-04	27	128	3	IPR001190
Domain	Cl-channel_core	CLCNKA CLCNKB	1.63e-03	9	128	2	IPR014743
Domain	-	CLCNKA CLCNKB	1.63e-03	9	128	2	1.10.3080.10
Domain	Voltage_CLC	CLCNKA CLCNKB	1.63e-03	9	128	2	PF00654
Domain	Cl-channel_volt-gated	CLCNKA CLCNKB	1.63e-03	9	128	2	IPR001807
Domain	Ldl_recept_a	TMPRSS15 TMPRSS6 TMPRSS7	3.62e-03	45	128	3	PF00057
Domain	-	TMPRSS15 TMPRSS6 TMPRSS7	3.85e-03	46	128	3	4.10.400.10
Domain	Zip	SLC39A10 SLC39A13	4.02e-03	14	128	2	PF02535
Domain	ZIP	SLC39A10 SLC39A13	4.02e-03	14	128	2	IPR003689
Domain	ConA-like_dom	TMPRSS15 TRIM11 PTPRM HNRNPUL2 WDFY3 NEURL4	4.02e-03	219	128	6	IPR013320
Domain	LDLRA_1	TMPRSS15 TMPRSS6 TMPRSS7	4.34e-03	48	128	3	PS01209
Domain	LDLRA_2	TMPRSS15 TMPRSS6 TMPRSS7	4.60e-03	49	128	3	PS50068
Domain	LDrepeatLR_classA_rpt	TMPRSS15 TMPRSS6 TMPRSS7	4.60e-03	49	128	3	IPR002172
Domain	LDLa	TMPRSS15 TMPRSS6 TMPRSS7	4.60e-03	49	128	3	SM00192
Domain	N2O_reductase_N	SEH1L PEX7	4.62e-03	15	128	2	IPR011045
Domain	CBS	CLCNKA CLCNKB	5.25e-03	16	128	2	SM00116
Domain	MAM_1	TMPRSS15 PTPRM	5.25e-03	16	128	2	PS00740
Domain	Sushi	TPO CSMD2 CSMD3	5.44e-03	52	128	3	PF00084
Domain	SOLCAR	SLC25A37 SLC25A39 SLC25A11	5.74e-03	53	128	3	PS50920
Domain	-	SLC25A37 SLC25A39 SLC25A11	5.74e-03	53	128	3	1.50.40.10
Domain	Mitochondrial_sb/sol_carrier	SLC25A37 SLC25A39 SLC25A11	5.74e-03	53	128	3	IPR018108
Domain	Mito_carr	SLC25A37 SLC25A39 SLC25A11	5.74e-03	53	128	3	PF00153
Domain	Mt_carrier_dom	SLC25A37 SLC25A39 SLC25A11	5.74e-03	53	128	3	IPR023395
Domain	Kringle	F2 F12	5.93e-03	17	128	2	IPR000001
Domain	Kringle_CS	F2 F12	5.93e-03	17	128	2	IPR018056
Domain	KRINGLE_2	F2 F12	5.93e-03	17	128	2	PS50070
Domain	Kringle	F2 F12	5.93e-03	17	128	2	PF00051
Domain	KRINGLE_1	F2 F12	5.93e-03	17	128	2	PS00021
Domain	MAM	TMPRSS15 PTPRM	5.93e-03	17	128	2	SM00137
Domain	KR	F2 F12	5.93e-03	17	128	2	SM00130
Domain	CCP	TPO CSMD2 CSMD3	6.05e-03	54	128	3	SM00032
Domain	MAM	TMPRSS15 PTPRM	6.64e-03	18	128	2	PF00629
Domain	MAM_dom	TMPRSS15 PTPRM	6.64e-03	18	128	2	IPR000998
Domain	MAM_2	TMPRSS15 PTPRM	6.64e-03	18	128	2	PS50060
Domain	SUSHI	TPO CSMD2 CSMD3	6.69e-03	56	128	3	PS50923
Pubmed	Developmental expression of voltage-gated potassium channel beta subunits.	KCNAB2 KCNAB1 KCNAB3	5.34e-08	3	132	3	10536234
Pubmed	Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product.	KCNAB2 KCNAB1 KCNAB3	5.34e-08	3	132	3	7649300
Pubmed	A new K+ channel beta subunit to specifically enhance Kv2.2 (CDRK) expression.	KCNAB2 KCNAB1 KCNAB3	2.13e-07	4	132	3	8824288
Pubmed	RT-PCR of fatty acid elongases.	SLC35G4 SLC35G3 SLC35G5	2.13e-07	4	132	3	9056918
Pubmed	Emergence of primate genes by retrotransposon-mediated sequence transduction.	SLC35G4 SLC35G3 SLC35G5	2.13e-07	4	132	3	17101974
Pubmed	Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.	PKD1L2 CSMD2 CSMD3 PWWP2A TRAPPC9	4.30e-06	63	132	5	11572484
Pubmed	The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.	CLCNKA CLCNKB	1.43e-05	2	132	2	27335120
Pubmed	Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.	CDC14C CDC14B	1.43e-05	2	132	2	19923902
Pubmed	Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.	CLCNKA CLCNKB	1.43e-05	2	132	2	8812470
Pubmed	The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.	CDC14C CDC14B	1.43e-05	2	132	2	21502810
Pubmed	Leucine-rich repeat transmembrane proteins are essential for maintenance of long-term potentiation.	LRRTM1 LRRTM2	1.43e-05	2	132	2	23931994
Pubmed	Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.	CLCNKA CLCNKB	1.43e-05	2	132	2	25919862
Pubmed	Myocardial Blood Flow Control by Oxygen Sensing Vascular Kvβ Proteins.	KCNAB2 KCNAB1	1.43e-05	2	132	2	33499656
Pubmed	Genetic modifiers of the Kv beta2-null phenotype in mice.	KCNAB2 KCNAB1	1.43e-05	2	132	2	15720404
Pubmed	Interactions between ICAM-5 and β1 integrins regulate neuronal synapse formation.	ITGB1 ICAM5	1.43e-05	2	132	2	23015592
Pubmed	Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.	CDC14C CDC14B	1.43e-05	2	132	2	18547142
Pubmed	Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility.	PEX7 TYSND1	1.43e-05	2	132	2	23459139
Pubmed	Localization of two potassium channel beta subunit genes, KCNA1B and KCNA2B.	KCNAB2 KCNAB1	1.43e-05	2	132	2	8838324
Pubmed	Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.	CLCNKA CLCNKB	1.43e-05	2	132	2	38069401
Pubmed	A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.	CLCNKA CLCNKB	1.43e-05	2	132	2	20805576
Pubmed	Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel.	KCNAB1 KCNAB3	1.43e-05	2	132	2	9857044
Pubmed	Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions.	MYO3A MYO3B	1.43e-05	2	132	2	27582493
Pubmed	Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS.	SLC25A37 SLC25A39	1.43e-05	2	132	2	35513392
Pubmed	Salt wasting and deafness resulting from mutations in two chloride channels.	CLCNKA CLCNKB	1.43e-05	2	132	2	15044642
Pubmed	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.	CLCNKA CLCNKB	1.43e-05	2	132	2	8041726
Pubmed	A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.	CLCNKA CLCNKB	1.43e-05	2	132	2	18648499
Pubmed	Mouse class III myosins: kinase activity and phosphorylation sites.	MYO3A MYO3B	1.43e-05	2	132	2	21895655
Pubmed	Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.	CLCNKA CLCNKB	1.43e-05	2	132	2	8544406
Pubmed	Deletion of LRRTM1 and LRRTM2 in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons.	LRRTM1 LRRTM2	1.43e-05	2	132	2	29784826
Pubmed	Shaker K+ channel beta subunits belong to an NAD(P)H-dependent oxidoreductase superfamily.	KCNAB2 KCNAB1	1.43e-05	2	132	2	8001150
Pubmed	Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.	CLCNKA CLCNKB	1.43e-05	2	132	2	24863058
Pubmed	Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.	CLCNKA CLCNKB	1.43e-05	2	132	2	9916798
Pubmed	Kidney kinetics and chloride ion pumps.	CLCNKA CLCNKB	1.43e-05	2	132	2	9916791
Pubmed	TD-92, a novel erlotinib derivative, depletes tumor-associated macrophages in non-small cell lung cancer via down-regulation of CSF-1R and enhances the anti-tumor effects of anti-PD-1.	PDCD1 CSF1R	1.43e-05	2	132	2	33232786
Pubmed	Nuclear calcium signaling induces expression of the synaptic organizers Lrrtm1 and Lrrtm2.	LRRTM1 LRRTM2	1.43e-05	2	132	2	25527504
Pubmed	Distinct but overlapping roles of LRRTM1 and LRRTM2 in developing and mature hippocampal circuits.	LRRTM1 LRRTM2	1.43e-05	2	132	2	35662394
Pubmed	Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.	CLCNKA CLCNKB	1.43e-05	2	132	2	11014860
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	SLC43A2 HTR6 PMPCB EI24 SLC39A13 SLC25A39 DHCR24 NLE1 SLC25A11 TAP1 ATP2B1 TCTN2	1.49e-05	697	132	12	28298427
Pubmed	Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.	CLCNKA CLCNKB	4.28e-05	3	132	2	26013830
Pubmed	Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.	CDC14C CDC14B	4.28e-05	3	132	2	21262768
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD3	4.28e-05	3	132	2	12906867
Pubmed	The potassium channel subunit Kvbeta3 interacts with pannexin 1 and attenuates its sensitivity to changes in redox potentials.	KCNAB1 KCNAB3	4.28e-05	3	132	2	19780818
Pubmed	Barttin increases surface expression and changes current properties of ClC-K channels.	CLCNKA CLCNKB	4.28e-05	3	132	2	12111250
Pubmed	Fate of membrane-bound reactants and products during the activation of human prothrombin by prothrombinase.	F2 F12	4.28e-05	3	132	2	18765660
Pubmed	Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.	CLCNKA CLCNKB	4.28e-05	3	132	2	17510212
Pubmed	Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.	CDC14C CDC14B	4.28e-05	3	132	2	22355704
Pubmed	Barttin modulates trafficking and function of ClC-K channels.	CLCNKA CLCNKB	4.28e-05	3	132	2	16849430
Pubmed	Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.	PELI3 PELI1	4.28e-05	3	132	2	27302665
Pubmed	Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance.	CLCNKA CLCNKB	4.28e-05	3	132	2	18094726
Pubmed	Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor.	CLCNKA CLCNKB	4.28e-05	3	132	2	10982849
Pubmed	Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin.	MYO3A MYO3B	4.28e-05	3	132	2	26785147
Pubmed	Differential contribution of tissue factor and Factor XII to thrombin generation triggered by breast and pancreatic cancer cells.	F2 F12	4.28e-05	3	132	2	29075790
Pubmed	Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.	F2 ITGB1	4.28e-05	3	132	2	18048360
Pubmed	Homozygosity for the C46T polymorphism of the F12 gene is a risk factor for venous thrombosis during the first pregnancy.	F2 F12	4.28e-05	3	132	2	17408404
Pubmed	Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.	MYO3A MYO3B	4.28e-05	3	132	2	22264607
Pubmed	Rapid triplex asymmetric real-time PCR hybridization probe assay for the joint genotyping of F2, F5 and F12.	F2 F12	4.28e-05	3	132	2	19422815
Pubmed	CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes.	CDC14C CDC14B	4.28e-05	3	132	2	19129509
Pubmed	Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.	CDC14C CDC14B	4.28e-05	3	132	2	26283732
Pubmed	The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth.	F2 ITGB1	4.28e-05	3	132	2	24790104
Pubmed	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.	CLCNKA CLCNKB	4.28e-05	3	132	2	11734858
Pubmed	Five prothrombotic polymorphisms and the prevalence of premature myocardial infarction.	F2 F12	4.28e-05	3	132	2	15749685
Pubmed	Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits.	KCNAB2 KCNAB1	4.28e-05	3	132	2	8636142
Pubmed	Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts.	LRRTM1 LRRTM2	8.54e-05	4	132	2	27565350
Pubmed	Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.	MYO3A MYO3B	8.54e-05	4	132	2	26926603
Pubmed	Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms.	LRRTM1 LRRTM2	8.54e-05	4	132	2	21708131
Pubmed	Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes.	CDC14C CDC14B	8.54e-05	4	132	2	32341029
Pubmed	Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption.	CLCNKA CLCNKB	8.54e-05	4	132	2	17652939
Pubmed	CDC14A phosphatase is essential for hearing and male fertility in mouse and human.	CDC14C CDC14B	8.54e-05	4	132	2	29293958
Pubmed	Genetics University of Toronto Thrombophilia Study in Women (GUTTSI): genetic and other risk factors for venous thromboembolism in women.	F2 MTRR	8.54e-05	4	132	2	11806787
Pubmed	Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis.	LRRTM1 LRRTM2	8.54e-05	4	132	2	16860615
Pubmed	Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases.	PELI3 PELI1	8.54e-05	4	132	2	16884718
Pubmed	Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.	PELI3 PELI1	8.54e-05	4	132	2	19081057
Pubmed	Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene.	ADAMTSL1 TRIM11	8.54e-05	4	132	2	25271088
Pubmed	Neuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neurons.	LRRTM1 LRRTM2	8.54e-05	4	132	2	21788371
Pubmed	Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.	KCNAB2 KCNAB1	8.54e-05	4	132	2	15662035
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	LAPTM4A EI24 HM13 ITGB1 LPCAT3 DHCR24 SLC25A11 SIPA1L2 TAP1	1.28e-04	499	132	9	22810586
Pubmed	The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.	F2 F12	1.42e-04	5	132	2	19415820
Pubmed	Cutting edge: CD28 engagement releases antigen-activated invariant NKT cells from the inhibitory effects of PD-1.	PDCD1 TAP1	1.42e-04	5	132	2	19454657
Pubmed	Major and potential prothrombotic genotypes in patients with venous thrombosis and in healthy subjects from Slovenia.	F2 F12	1.42e-04	5	132	2	19127083
Pubmed	A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system.	LRRTM1 LRRTM2	1.42e-04	5	132	2	12676565
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPOCK2 HEATR5A SLC39A10 CSMD3 WDR47 LRRTM2 ARHGEF4 SIPA1L2	1.71e-04	407	132	8	12693553
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRIO TMPRSS6 WDR27 HM13 ITGB1 CDC14B SLC25A37 PCNX2 DNAAF5 BMPR1B WDR11 LPCAT3 ARHGEF4 CATSPERG ATP2B1 TRAPPC9	1.72e-04	1489	132	16	28611215
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNAB2 CLCNKA CLCNKB KCNAB1 KCNAB3	1.95e-04	139	132	5	16985003
Pubmed	Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.	KCNAB2 KCNAB1	2.12e-04	6	132	2	10477520
Pubmed	Predictive role of coagulation-balance gene polymorphisms in the efficacy of photodynamic therapy with verteporfin for classic choroidal neovascularization secondary to age-related macular degeneration.	F2 MTRR	2.12e-04	6	132	2	18004208
Pubmed	The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities.	PELI3 PELI1	2.12e-04	6	132	2	25027698
Pubmed	Vasculopathic and thrombophilic risk factors for spontaneous preterm birth.	F2 MTRR	2.12e-04	6	132	2	19336437
Pubmed	Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases.	PELI3 PELI1	2.12e-04	6	132	2	17675297
Pubmed	Coagulation gene predictors of photodynamic therapy for occult choroidal neovascularization in age-related macular degeneration.	F2 MTRR	2.12e-04	6	132	2	18378576
Pubmed	Role of thrombophilic gene polymorphisms in branch retinal vein occlusion.	F2 F12	2.12e-04	6	132	2	16157382
Pubmed	Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency.	CLCNKA CLCNKB	2.97e-04	7	132	2	34499620
Pubmed	Transport of Iodothyronines by Human L-Type Amino Acid Transporters.	SLC43A2 SLC16A2	2.97e-04	7	132	2	26305885
Pubmed	Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.	MYO3A MYO3B	2.97e-04	7	132	2	19332056
Pubmed	Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney.	CLCNKA CLCNKB	2.97e-04	7	132	2	11423561
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	TPO ADAMTSL1 MYO3A CSF1R	3.02e-04	84	132	4	15203218
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CCDC71L TRIO ANKLE1 LYST CDC14B PCNX2 SLC25A39 ULK4 NLE1 WDFY3 ARHGEF4 SIPA1L2 TRAPPC9	3.08e-04	1105	132	13	35748872
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	AAMP TBPL1 EI24 PELI1 LYST DNAAF5 MTRR TAP1	3.72e-04	457	132	8	32968282
Pubmed	The LZT proteins; the LIV-1 subfamily of zinc transporters.	SLC39A10 SLC39A13	3.94e-04	8	132	2	12659941
Pubmed	Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner.	PELI3 PELI1	3.94e-04	8	132	2	15917247
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	LCAT F2 ITGB1 F12 CSF1R PTPRM	4.63e-04	257	132	6	16335952
Cytoband	12q24.31	HCAR1 SBNO1 KDM2B TCTN2	8.72e-05	80	132	4	12q24.31
GeneFamily	WD repeat domain containing	SEH1L AAMP PEX7 WDR27 WDFY4 LYST WDR47 EML5 WDR11 TLE2 UTP4 NLE1 WDFY3	1.12e-09	262	95	13	362
GeneFamily	Proteases, serine	TMPRSS15 TMPRSS6 TMPRSS12 PRSS33 PRSS42P PRSS45P TMPRSS7	3.85e-08	63	95	7	738
GeneFamily	Solute carriers	SLC43A2 SLC27A6 SLC39A10 SLC25A37 SLC39A13 SLC35G4 SLC7A9 SLC16A2 SLC25A39 SLC35G3 SLC35G5 SLC25A11 SLC38A8	1.46e-07	395	95	13	752
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDFY4 LYST WDFY3	1.15e-05	9	95	3	1230
GeneFamily	Myosins, class III\|Deafness associated genes	MYO3A MYO3B	2.73e-05	2	95	2	1099
GeneFamily	Potassium voltage-gated channel regulatory subunits\|DASH family	KCNAB2 KCNAB1 KCNAB3	6.11e-05	15	95	3	858
GeneFamily	Aldo-keto reductases	KCNAB2 KCNAB1 KCNAB3	6.11e-05	15	95	3	399
GeneFamily	Pellino E3 ubiquitin protein ligases	PELI3 PELI1	8.17e-05	3	95	2	676
GeneFamily	Chloride voltage-gated channels	CLCNKA CLCNKB	1.20e-03	10	95	2	302
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	TPO CSMD2 CSMD3	3.35e-03	57	95	3	1179
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	WDR27 ASPHD2 CSMD2 CSMD3 MYO3A LRRTM2 KCNAB1 TRAPPC9	1.16e-07	193	132	8	088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_4\|390C / Donor, Lineage, Cell class and subclass (all cells)	PDCD1 GALM TMPRSS6 PELI1 SPOCK2 LRRTM2	6.69e-06	154	132	6	a90c4c45685eae8d21d03479cfd5a23f6ed3ca07
ToppCell	10x5'v1-week_12-13-Myeloid_DC-DC-DC1\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	WDFY4 CHRNB2 MYO3B FBXO41 TAP1 ATP2B1	1.14e-05	169	132	6	319511ea57bbd72c2d95e8516d093689df67a912
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 ATP8B4 KCNAB2 CSF1R ATF7IP UTP4	1.58e-05	179	132	6	30efe1f0394c0edb27b91890b5c4637b73cbc5ec
ToppCell	COVID_vent-Myeloid-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ATP8B4 TRIO GRN WDFY4 CSF1R ATP2B1	1.96e-05	186	132	6	63a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell	COVID_vent-Myeloid-Dendritic-cDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ATP8B4 TRIO GRN WDFY4 CSF1R ATP2B1	1.96e-05	186	132	6	39457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell	Control-Myeloid\|Control / group, cell type (main and fine annotations)	SLC43A2 KCNAB2 GRN WDFY4 CSF1R CD163L1	2.27e-05	191	132	6	9c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC43A2 ATP8B4 PELI1 CSF1R CD163L1 LOXL3	2.48e-05	194	132	6	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	SLC27A6 TMPRSS6 PELI1 SPOCK2 ICAM5 SIPA1L2	2.48e-05	194	132	6	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	SLC43A2 KCNAB2 GRN WDFY4 SIPA1L2 ATP2B1	2.55e-05	195	132	6	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	ATP8B4 SLC27A6 GRN WDFY4 CSF1R CD163L1	2.63e-05	196	132	6	a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC71L SLC43A2 PELI1 SLC25A37 CSF1R ATP2B1	2.63e-05	196	132	6	c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC71L SLC43A2 PELI1 SLC25A37 CSF1R ATP2B1	2.63e-05	196	132	6	64c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP8B4 TMPRSS6 PELI1 ASPHD2 CSF1R CD163L1	2.70e-05	197	132	6	e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP8B4 F2 WDFY4 CSF1R FBXO41 INSYN2B	2.70e-05	197	132	6	e0fc098bfb5a8b7824ae339f3adda30f78360d0b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDCD1 GALM SPOCK2 ITGB1 P2RY10 TAP1	2.70e-05	197	132	6	7c9df6025b9d168bd6d041c6cff1e87e08b11847
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP8B4 WDFY4 CSF1R SLC35G3 CD163L1 LOXL3	2.78e-05	198	132	6	c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC43A2 ATP8B4 KCNAB2 WDFY4 CSF1R LOXL3	2.86e-05	199	132	6	1413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6.Tcf4_(Supramammillary_Nucleus_(SuM))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ATP8B4 TMPRSS6 SLC7A9 TGM4	3.24e-05	61	132	4	46cdf693c7f2df4fc43df7837b152871af67bef0
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6.Tcf4_(Supramammillary_Nucleus_(SuM))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ATP8B4 TMPRSS6 SLC7A9 TGM4	3.24e-05	61	132	4	c73fa489427a6e11badbdfc0324008137806ac7d
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6.Tcf4_(Supramammillary_Nucleus_(SuM))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ATP8B4 TMPRSS6 SLC7A9 TGM4	3.24e-05	61	132	4	c2c633f49f6ad8581c33794c909f40aa59f0b5c5
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TPO F12 CD163L1 SLC38A8	4.43e-05	66	132	4	85e0027bf0d4ebdcb6cac358aedd1d74aa83c612
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(peripeduncular_nucleus_&_posterior_intralaminar_thalamic_nucleus_(PP_&_PIL))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TPO F12 CD163L1 SLC38A8	4.43e-05	66	132	4	6cf03dd1db7607684cdcca7df08933f8cdc3adef
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A37 NAGS SLC25A39 DGKK CATSPERG	5.91e-05	139	132	5	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A37 NAGS SLC25A39 DGKK CATSPERG	5.91e-05	139	132	5	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TMPRSS15 ADAMTSL1 CSMD2 CSMD3 MYO3A	7.96e-05	148	132	5	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TMPRSS6 PRSS33 MYO3B ATP2B1	8.11e-05	77	132	4	10969743351c49a1d6d8ae1ef93098e7786ca3fe
ToppCell	droplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	8.75e-05	151	132	5	cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell	Influenza_Severe-CD4+_CTL\|World / Disease group and Cell class	PDCD1 GALM SPOCK2 ITGB1 TGM4	9.31e-05	153	132	5	0c6c2c6dbc81badd886f125f4e5ba0fb7d52101c
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRTM1 PKD1L2 PCNX2 BMPR1B CSF1R	9.31e-05	153	132	5	8cc2667213bfac37545bb63181e88ef1f1834413
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRTM1 PKD1L2 PCNX2 BMPR1B CSF1R	9.31e-05	153	132	5	596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Wif1_(Medial_habenular,_lateral_portion)\|Thalamus / BrainAtlas - Mouse McCarroll V32	TMPRSS15 F2 MYO3B TMPRSS7	9.42e-05	80	132	4	da18df34b4f630fe4fe3110e3c3c3602aef92aab
ToppCell	facs-Marrow-KLS-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 ADRB1 SLC16A2 ICAM5 PCDHGC3	9.60e-05	154	132	5	37765512dfae557b9f6eb30a29463b93682a4404
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 EML5 P2RY10 SLC25A11 SLC38A8	1.08e-04	158	132	5	91d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 LYST CHRNB2 CSF1R KCNAB3	1.08e-04	158	132	5	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 LYST CHRNB2 CSF1R KCNAB3	1.08e-04	158	132	5	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GALM SPOCK2 ITGB1 P2RY10 PRSS45P	1.12e-04	159	132	5	6599707107083af6da092fe8984afc8fd89d2bb8
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GALM SPOCK2 ITGB1 P2RY10 PRSS45P	1.12e-04	159	132	5	916d070d099726f22deb71966efccff00f8ea071
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANKLE1 ADRB1 CLCNKA CLCNKB PNMA6A	1.15e-04	160	132	5	9049707a4487f2337a17976ceb5fbd8815ab9e1d
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANKLE1 ADRB1 CLCNKA CLCNKB PNMA6A	1.15e-04	160	132	5	f2cfec54cf48a655f473b830be7d141c54b521ff
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	DAND5 SPOCK2 TLE2 P2RY10 NEURL4	1.15e-04	160	132	5	8aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANKLE1 ADRB1 CLCNKA CLCNKB PNMA6A	1.15e-04	160	132	5	0eb50b3c494e1b65d40104b3b5411b57bb72b959
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 SPOCK2 EML5 CD163L1 P2RY10	1.18e-04	161	132	5	140b3c7077947c541cff54f6754e2df968345f4d
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PCNX2 ADRB1 ICAM5 TMPRSS7 ATP2B1	1.18e-04	161	132	5	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tregs\|Liver / Manually curated celltypes from each tissue	GALM PELI1 SPOCK2 ITGB1 P2RY10	1.18e-04	161	132	5	e0fd0c5f72d6a2900827e7bc2608ce3b8df5686b
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.25e-04	163	132	5	03d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 GALM KDM2B NLE1 NEURL4	1.25e-04	163	132	5	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.25e-04	163	132	5	1c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCell	droplet-Liver-Hepatocytes-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.25e-04	163	132	5	7e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 GALM KDM2B NLE1 NEURL4	1.25e-04	163	132	5	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 GALM P2RY10 KDM2B INSYN2B	1.29e-04	164	132	5	54f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 BMPR1B CLCNKB SLC25A39 TMPRSS7	1.33e-04	165	132	5	a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.33e-04	165	132	5	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	severe_influenza-CD4+_CTL\|World / disease group, cell group and cell class (v2)	PDCD1 SPOCK2 ITGB1 TGM4 SLC16A2	1.36e-04	166	132	5	cdc3e200373718f26fe02ee516928097103f46e2
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SLC43A2 WDFY4 CLCNKA CLCNKB PNMA6A	1.36e-04	166	132	5	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLC43A2 CSMD2 WDFY4 CLCNKA CLCNKB	1.44e-04	168	132	5	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.44e-04	168	132	5	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.44e-04	168	132	5	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.48e-04	169	132	5	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT F2 F12 DHCR24	1.48e-04	169	132	5	7785cab967a33560830c394c918d6ce625103858
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR6 SPOCK2 ASPHD2 MYO3B P2RY10	1.57e-04	171	132	5	8719a18c9e6b6f5d8ec4e937c2bda1e36441c9ec
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR6 SPOCK2 ASPHD2 MYO3B P2RY10	1.57e-04	171	132	5	f4cdd7862c8fe99ee765a2f3ed375b584f4976c5
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TMPRSS6 HCAR1 SPOCK2 TSPAN1 MYO3B	1.61e-04	172	132	5	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells-mDC\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDCD1 ASPHD2 WDFY4 CSF1R P2RY10	1.61e-04	172	132	5	cc0e2a45fa74ee19e41612c3615729462474003a
ToppCell	facs-Aorta-Heart-3m-Myeloid\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDFY4 LYST SLC25A37 SLC25A39 P2RY10	1.65e-04	173	132	5	513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CSMD2 HHLA1 CLCNKA CLCNKB PNMA6A	1.70e-04	174	132	5	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CSMD2 HHLA1 CLCNKA CLCNKB PNMA6A	1.70e-04	174	132	5	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Control / Condition, Lineage and Cell class	ATP8B4 SLC7A9 CD163L1 LHFPL6 PCDHGC3	1.70e-04	174	132	5	4c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell	droplet-Bladder-Unstain-18m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 KCNAB2 CSF1R CD163L1 P2RY10	1.70e-04	174	132	5	773329bb91b97578df138446cf62101dd0dad758
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CSMD2 HHLA1 CLCNKA CLCNKB PNMA6A	1.70e-04	174	132	5	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CSMD2 HHLA1 CLCNKA CLCNKB PNMA6A	1.70e-04	174	132	5	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	normal_Lung-T/NK_cells-Treg\|normal_Lung / Location, Cell class and cell subclass	PDCD1 GALM TMPRSS6 SPOCK2 P2RY10	1.75e-04	175	132	5	bc846312e6a6d68b7ca661052fb4e02cfb8ed014
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	LAPTM4A TMPRSS6 ITGB1 TLE2 LHFPL6	1.79e-04	176	132	5	ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PDCD1 ATP8B4 LYST LPCAT3 SIPA1L2	1.79e-04	176	132	5	56c055488e34605d32562571a2fee621b47c9441
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	ATP8B4 SLC7A9 CD163L1 LHFPL6 PCDHGC3	1.84e-04	177	132	5	470f54fe2b21c7350ea471e02039461a3808f700
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HCAR1 TSPAN1 CLCNKB SLC25A39 SLC25A11	1.89e-04	178	132	5	f1cfc348d51362eb8c92c625f21f682afc0352b7
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CCDC71L SEH1L PDCD1 EXO5 MTRR	1.89e-04	178	132	5	8151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 LCAT SLC7A9 BMPR1B LHFPL6	1.94e-04	179	132	5	7ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR27 DNAAF5 CD163L1 MYO3B ARHGEF4	1.99e-04	180	132	5	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	TPO SPNS2 ADRB1 PTPRM LHFPL6	2.04e-04	181	132	5	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTSL1 PRSS33 F12 EML5 FBXO41	2.04e-04	181	132	5	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS6 TSPAN1 BMPR1B CLCNKB TLE2	2.09e-04	182	132	5	fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Treg\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDCD1 KCNAB2 SPOCK2 ASPHD2 P2RY10	2.15e-04	183	132	5	450c30d2e389fcb17825394c27f9ccc4f33022e3
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CCDC71L SEH1L PDCD1 EXO5 WDR11	2.20e-04	184	132	5	2c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A2 TMPRSS6 TGM4 CLCNKA CLCNKB	2.26e-04	185	132	5	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EI24 SPOCK2 HHLA1 SLC25A37 BMPR1B	2.26e-04	185	132	5	fcd95bc074e982fc7b8fd48d2e80038b9ea35ebb
ToppCell	mild_COVID-19-CD4+_CTL\|mild_COVID-19 / disease group, cell group and cell class (v2)	PDCD1 GALM SPOCK2 ITGB1 PTPRM	2.37e-04	187	132	5	49196d07e4716c87d33229a4569bdb6b4613b3eb
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KCNAB2 CHRNB2 PCNX2 INSYN2B KCNAB3	2.37e-04	187	132	5	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 HCAR1 ADRB1 CLCNKB SLC25A39	2.37e-04	187	132	5	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	SLC43A2 ADAMTSL1 CSMD3 BMPR1B CLCNKB	2.37e-04	187	132	5	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP8B4 WDFY4 CSF1R CD163L1 KCNAB1	2.43e-04	188	132	5	8fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDCD1 KCNAB2 SPOCK2 TRIM11 P2RY10	2.49e-04	189	132	5	c38157c8cf5c0c1f560011ef5cc5892a049ee2b7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP8B4 WDFY4 CSF1R CD163L1 LOXL3	2.55e-04	190	132	5	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	LAPTM4A TMPRSS6 SLC16A2 TLE2 LHFPL6	2.55e-04	190	132	5	ec0ab31266583a0966ac7615d5c0fabb7b7e66e8
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP8B4 WDFY4 CSF1R CD163L1 KCNAB1	2.55e-04	190	132	5	912aa106581d1ed7e147c92f9a367e8e6b04052b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRIO PELI1 WDFY4 P2RY10 ATP2B1	2.55e-04	190	132	5	0db545a4cba7534bad2693e0d565cde7dbc7a586
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC43A2 ADRB1 CLCNKA CLCNKB SLC25A39	2.62e-04	191	132	5	8b34e06c398056e857a10c7653c70c0b1f181692
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	ATP8B4 KCNAB2 WDFY4 CD163L1 INSYN2B	2.62e-04	191	132	5	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP8B4 WDFY4 CSF1R CD163L1 LOXL3	2.62e-04	191	132	5	baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC71L SLC43A2 PELI1 SLC25A37 ATP2B1	2.62e-04	191	132	5	0b296404ebad0aadb75737f8c0462ec6934fc8bb
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	WDFY4 LYST WDFY3	3.18e-07	4	128	3	DOID:2935 (implicated_via_orthology)
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	GRN CLCNKA CLCNKB	9.36e-06	10	128	3	DOID:12387 (implicated_via_orthology)
Disease	Bartter disease type 4B	CLCNKA CLCNKB	1.87e-05	2	128	2	cv:C4310805
Disease	Bartter disease type 3 (implicated_via_orthology)	CLCNKA CLCNKB	1.87e-05	2	128	2	DOID:0110144 (implicated_via_orthology)
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	1.87e-05	2	128	2	613090
Disease	BARTTER SYNDROME, TYPE 4B	CLCNKA CLCNKB	1.87e-05	2	128	2	C2751312
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	1.87e-05	2	128	2	C4310805
Disease	Bartter disease type 4b (is_implicated_in)	CLCNKA CLCNKB	1.87e-05	2	128	2	DOID:0110146 (is_implicated_in)
Disease	Bartter disease (implicated_via_orthology)	CLCNKA CLCNKB	1.87e-05	2	128	2	DOID:445 (implicated_via_orthology)
Disease	acquired angioedema (is_marker_for)	F2 F12	5.59e-05	3	128	2	DOID:0080941 (is_marker_for)
Disease	hereditary angioedema (is_marker_for)	F2 F12	1.11e-04	4	128	2	DOID:14735 (is_marker_for)
Disease	blood chromium measurement	ADRB1 PTPRM ARHGEF4	1.93e-04	26	128	3	EFO_0007579
Disease	Bartter syndrome	CLCNKA CLCNKB	2.77e-04	6	128	2	cv:C0004775
Disease	Calcium channel blocker use measurement	CCDC71L SLC27A6 TBPL1 ADRB1 KDM2B ATP2B1	3.44e-04	213	128	6	EFO_0009930
Disease	ascending aortic diameter	SLC27A6 SLC25A37 ULK4 ATP2B1 TRAPPC9	3.71e-04	140	128	5	EFO_0021787
Disease	hip circumference, psychosocial stress measurement	ADAMTSL1 TRIM11	3.87e-04	7	128	2	EFO_0005093, EFO_0006783
Disease	Schizophrenia	HTR6 GRN LRRTM1 CSMD2 F2 CHRNB2 EML5 WDR11 SBNO1 KDM2B ULK4 TAP1	4.75e-04	883	128	12	C0036341
Disease	thrombin measurement	F2 F12	5.14e-04	8	128	2	EFO_0020768
Disease	dynein light chain roadblock-type 1 measurement	OR11L1 CDC14B	5.14e-04	8	128	2	EFO_0008114
Disease	bone morphogenetic protein 7 measurement	CDC14B F12	8.21e-04	10	128	2	EFO_0020187
Disease	glomerulonephritis (is_implicated_in)	TPO F2	1.00e-03	11	128	2	DOID:2921 (is_implicated_in)
Disease	hyperhomocysteinemia (implicated_via_orthology)	F2 F12	1.00e-03	11	128	2	DOID:9279 (implicated_via_orthology)
Disease	systolic blood pressure, alcohol consumption measurement	CCDC71L ADRB1 ATP2B1	1.12e-03	47	128	3	EFO_0006335, EFO_0007878
Disease	Thromboembolism	F2 F12	1.20e-03	12	128	2	C0040038
Disease	autoimmune hepatitis (is_implicated_in)	PDCD1 F2	1.41e-03	13	128	2	DOID:2048 (is_implicated_in)
Disease	triacylglycerol 46:2 measurement	PMPCB MYO3B	1.64e-03	14	128	2	EFO_0010402
Disease	diastolic blood pressure, alcohol consumption measurement	ADRB1 ULK4 ATP2B1	1.68e-03	54	128	3	EFO_0006336, EFO_0007878
Disease	infant head circumference	ADRB1 SBNO1	1.89e-03	15	128	2	EFO_0004577
Disease	lung small cell carcinoma (is_marker_for)	ITGB1 CSF1R	2.15e-03	16	128	2	DOID:5409 (is_marker_for)
Disease	response to opioid	SLC25A37 SLC7A9 ADRB1	2.39e-03	61	128	3	EFO_0008541
Disease	Dementia	GRN CSF1R	2.43e-03	17	128	2	C0497327
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TRIO ATP2B1	2.43e-03	17	128	2	DOID:0060307 (is_implicated_in)
Disease	CCL5 measurement	CCDC71L DIS3L2 F12	2.74e-03	64	128	3	EFO_0005117
Disease	myocardial infarction (implicated_via_orthology)	LCAT ITGB1 ADRB1	2.99e-03	66	128	3	DOID:5844 (implicated_via_orthology)
Disease	hydrocephalus (implicated_via_orthology)	ITGB1 ULK4	3.04e-03	19	128	2	DOID:10908 (implicated_via_orthology)
Disease	toxic shock syndrome (is_marker_for)	PDCD1 F2	3.04e-03	19	128	2	DOID:14115 (is_marker_for)
Disease	schizophrenia (implicated_via_orthology)	LRRTM1 CSMD3 SBNO1	3.25e-03	68	128	3	DOID:5419 (implicated_via_orthology)
Disease	end stage renal disease (implicated_via_orthology)	LCAT F2	3.37e-03	20	128	2	DOID:783 (implicated_via_orthology)
Disease	pulse pressure measurement, alcohol drinking	CCDC71L ULK4 ATP2B1	3.53e-03	70	128	3	EFO_0004329, EFO_0005763
Disease	pulse pressure measurement, alcohol consumption measurement	CCDC71L ATP2B1	4.07e-03	22	128	2	EFO_0005763, EFO_0007878

Protein segments in the cluster

Peptide	Gene	Start	Entry
RGLVCTVWAISALVS	ADRB1	176	P08588
TLVGIVSWGSRTCST	CTRB2	226	Q6GPI1
GSGSWIRVLASECIK	CATSPERG	331	Q6ZRH7
SGWVAAALCVVIALT	HTR6	26	P50406
LWDRAVEGLSCSISS	BTNL10	211	A8MVZ5
RQILDIWASGCGVVS	ANKLE1	521	Q8NAG6
GSEELLCLSGERRTW	CSMD2	1246	Q7Z408
LVGSAVRECLSSGLW	CSMD3	2791	Q7Z407
CSLDGIVRLWDARTG	AAMP	376	Q13685
TAAETIAWVRICRPG	CDC14B	336	O60729
RVSCSGVEALGRDWL	FAM220BP	111	B1ANY3
SWVALTAGLVAGTRC	GRN	6	P28799
TWALLCISAETVRGE	ARHGEF4	36	Q9NR80
CLGIILAIGNSIWES	ATP8B4	286	Q8TF62
VIVTCSGDATWGLRL	CD163L1	571	Q9NR16
ILDEWFGRTIIRSCT	DIS3L2	476	Q8IYB7
ILWEVARRCVSGGIV	BMPR1B	406	O00238
TAAETIAWVRICRPG	CDC14C	306	A4D256
VVWRGACLSTSRPVD	CECR2	376	Q9BXF3
TGWIEGAAILLSVVC	ATP2B1	151	P20020
TWVLLVCIGATSGLG	SLC16A2	356	P36021
CGSLIGWRNVTRLLV	ITGB1	261	P05556
ICEWRKGSGVLSSTL	EXO5	351	Q9H790
LSTCTVGLWIDAGSR	PMPCB	76	O75439
APVVLWCLTGSSASR	DAND5	156	Q8N907
RFRILVCGGDGSVSW	DGKK	541	Q5KSL6
CILLIAGSWVIGNTS	OR1A2	141	Q9Y585
RSLEVQCGAGLTLLW	KIAA0100	656	Q14667
ILCRELGFTEATGWT	LOXL3	81	P58215
RSLTTVGLSGNLWEC	LRRTM2	301	O43300
LTSITLAGNLWDCGR	LRRTM1	306	Q86UE6
KSGLRVSCLGLGTWV	KCNAB1	96	Q14722
SFIVVLVVWAGCSGL	SLC43A2	206	Q8N370
GCCHVRTGTIILGTW	LAPTM4A	21	Q15012
KGVCTGWLALLVASV	MTRR	486	Q9UBK8
GRLLCGASLVSSDWL	TMPRSS15	806	P98073
WSACTVTCGVGTQVR	ADAMTSL1	531	Q8N6G6
TLQESLCGDLVLGRW	PCNX2	1396	A6NKB5
WVLAVICSRAARGTI	PDCD1	186	Q15116
RITWLEGTEASLSCV	ICAM5	501	Q9UMF0
AGGRVETWCSVRPTV	PDZD7	376	Q9H5P4
GFAGLTSTVICRWTR	TPO	861	P07202
HVLITCSGDGSLQLW	PEX7	81	O00628
EGCTEVSLLRVGWSV	HNRNPUL2	306	Q1KMD3
TCWLVTEGVCILTGL	LPCAT3	286	Q6P1A2
KDLVCLGLSSIVGVW	HM13	161	Q8TCT9
GGIVSVETDLLQWCL	NAGS	236	Q8N159
CARLVVVSWCTGVST	OR11L1	141	Q8NGX0
WRSGLVSTGRVVGVL	PCDHGC3	6	Q9UN70
TCLQSGSWVLVGVVS	PRSS33	236	Q8NF86
GIPSAEWRICTIVTG	LHFPL6	76	Q9Y693
EWRICTIVTGLGCGL	LHFPL6	81	Q9Y693
RGAKVASLCVWLGVT	NPBWR2	161	P48146
GLRVSCLGLGTWVTF	KCNAB2	46	Q13303
ITREEGVLTLWRGCI	SLC25A11	171	Q02978
CILVGWLLVAATSGV	PKD1L2	1821	Q7Z442
CVQLATGSWTSGILV	OR2D2	141	Q9H210
SDLLRVDIISWGCTI	GALM	26	Q96C23
LEISFRIWQCGGTLE	GALNT1	321	Q10472
RIWQCGGTLEIVTCS	GALNT1	326	Q10472
SWSLDGLRDCIATGI	ASPHD2	36	Q6ICH7
ATVTLRCVGNGSVEW	CSF1R	36	P07333
TWQVTLEGRAGALCA	HEATR5A	601	Q86XA9
LRDLVLSGCSWIAVS	KDM2B	1151	Q8NHM5
ECLSGVLELVRSWIT	DCLRE1C	181	Q96SD1
WSCGTLGFLVAAEIR	DHCR24	216	Q15392
DLARGIKDSIWGICT	EI24	11	O14681
LIIWAACGVLATLGA	SLC7A9	66	P82251
GIVLSWSVLEVDRSC	ATF7IP	1176	Q6VMQ6
LISVSRDGTCIIWDL	LYST	3631	Q99698
EVIWALGAGCREIVS	FBXO41	701	Q8TF61
TISTRVAAGIVCTLW	HCAR1	126	Q9BXC0
TVATRSTELCGLWQG	LCAT	371	P04180
CFGGRTLEEIWRAAT	CCDC71L	171	Q8N9Z2
GTSTGDVCIWRDIFL	EML5	881	Q05BV3
ERVVGRWLLVCSGTV	COX15	66	Q7KZN9
RWLLVCSGTVAGAVI	COX15	71	Q7KZN9
VRRAVASVVGGWLLC	DNAAF5	261	Q86Y56
TVLASSGDDGCVRLW	SEH1L	291	Q96EE3
NIGASAWICGIISIT	SLC39A10	401	Q9ULF5
SGERLDTWICSLLGS	SLC39A13	61	Q96H72
VLCGSVLSVWTKVEG	SBNO1	1306	A3KN83
GSWVVSGCSVLRDGR	NEURL4	126	Q96JN8
GISAAIWIVVGTACL	P2RY10	151	O00398
CSAIGRTVAGDRLWL	PTPRM	206	P28827
VCNSLALGTWLGGTI	OR10G6	161	Q8NH81
GSLIDLCGATLLWRT	PELI1	241	Q96FA3
LCGATLLWRTAEGLS	PELI1	246	Q96FA3
SGLRVSCLGLGTWVT	KCNAB3	86	O43448
WCLRSEGVSSVLLGV	KCNAB3	351	O43448
RRLTLQGIISWGSGC	F12	576	P00748
GLACVLSLWNTVSGI	HHLA1	16	C9JL84
ILTGHTQSVTCLRWG	NLE1	241	Q9NVX2
TQSVTCLRWGGDGLL	NLE1	246	Q9NVX2
LSWSCVGAEGILALV	SLC35G5	251	Q96KT7
CIVWGVAFLSDGTII	UTP4	196	Q969X6
VTPDGRTICVGDIVW	PWWP2A	646	Q96N64
LSWSCVGAVGILALV	SLC35G3	251	Q8N808
GSLIDLCGATLLWRT	PELI3	291	Q8N2H9
CVSTDSGLLVGRWVP	PIGQ	11	Q9BRB3
AISCIRTVWRTEGLG	SLC25A37	181	Q9NYZ2
SCRDVIGWTSGLVSI	SIPA1L2	896	Q9P2F8
AVLWLGACGVLRATV	TAP1	66	Q03518
LGVVTGAGATRWCRL	SPNS2	376	Q8IVW8
GQCWVFAGILTTVLR	TGM4	266	P49221
CCLEVWGVVSVLVGT	SLC38A8	406	A6NNN8
SVAGALGVGLRRVCW	PNMA6A	121	P0CW24
LLRLCSGVWGTDTEE	CHRNB2	16	P17787
LFVTSRGRAVGCVSW	CLCNKA	656	P51800
LFVTSRGRAVGCVSW	CLCNKB	656	P51801
LSWSCVGAVGILTLV	SLC35G4	251	P0C7Q5
ACEVEGRWILAGVLS	PRSS45P	191	Q7RTY3
WDLRVPSCVRVVGTT	WDR47	781	O94967
ITATIWSSGKIICTG	TBPL1	56	P62380
IGGCTLSSWLTCRLA	TMEM196	121	Q5HYL7
VEVGDRTSWALGVCR	TRIM11	346	Q96F44
KLVITGGTSTVVCVW	WDFY3	3091	Q8IZQ1
ACVRTAVAQGGWRSL	SLC25A39	201	Q9BZJ4
CGASVISREWLLSAA	TMPRSS7	631	Q7RTY8
LGLVVWLTTCGRSEL	WDFY4	341	Q6ZS81
GRHICGGTLVTATWV	PRSS42P	101	Q7Z5A4
VCGGTLVRERWVLTA	TMPRSS12	106	Q86WS5
CGASLISDRWVLTAA	F2	391	P00734
WLGAALEGLCSASVI	TRAPPC9	241	Q96Q05
ENTRCVWIGSSVGLF	WDR27	316	A2RRH5
GSITCIAWKGDTLVL	WDR11	711	Q9BZH6
VLRGSAVLWAFGCTA	SLC27A6	241	Q9Y2P4
GTRLWTGGLDNTVRC	TLE2	601	Q04725
SRSGEWRLATGTVLC	TMEM125	61	Q96AQ2
VTTLHLWQSAGRGLC	TCTN2	456	Q96GX1
WGSGVAVAPRLVVTC	TYSND1	356	Q2T9J0
WCVDQLGLELTGTRT	SPOCK2	356	Q92563
RLLDCVVRWGSLTEG	TRIO	2876	O75962
TVLTATGWSLCRSLI	TMEM39B	166	Q9GZU3
ICGGALIADRWVITA	TMPRSS6	601	Q8IU80
LWLVVELCTGGSLKT	ULK4	71	Q96C45
CGAALLAVGIWVSID	TSPAN1	21	O60635
GPVSICLEAGTWRSL	INSYN2B	181	A6NMK8
LWLVLELCSGGSVTD	MYO3A	96	Q8NEV4
RCDVWSLGITAIELG	MYO3B	216	Q8WXR4