Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

EOMES SOX1 SRF GATA4 GATA6 HOXA13 FOXD3 DMRTA2 HHEX GATA5 SOX21 HOXD1 GSC FOXF2

3.30e-0912443314GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

EOMES SOX1 SRF GATA4 GATA6 HOXA13 FOXD3 DMRTA2 HHEX GATA5 SOX21 HOXD1 GSC FOXF2

4.35e-0912713314GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

EOMES SOX1 SRF GATA4 GATA6 HOXA13 FOXD3 DMRTA2 HHEX GATA5 SOX21 HOXD1 GSC FOXF2

1.67e-0814123314GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

EOMES SOX1 SRF GATA4 GATA6 HOXA13 FOXD3 DMRTA2 HHEX GATA5 SOX21 HOXD1 GSC FOXF2

2.54e-0814593314GO:0000977
GeneOntologyMolecularFunctiontranscription factor binding

EOMES SRF GATA4 GATA6 DNAJA3 ZNF703 HHEX XPC GSC FOXF2

2.31e-077533310GO:0008134
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

EOMES SRF GATA4 GATA6 DNAJA3 ZNF703 HHEX XPC GSC

2.95e-07582339GO:0140297
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

EOMES SRF GATA4 GATA6 DNAJA3 XPC GSC

4.40e-06417337GO:0061629
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

SOX1 SRF GATA4 HOXA13 HHEX SOX21 FOXF2

2.98e-05560337GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

SOX1 SRF GATA4 HOXA13 HHEX SOX21 FOXF2

3.19e-05566337GO:0001216
GeneOntologyMolecularFunctionNFAT protein binding

GATA4 GATA6

3.96e-056332GO:0051525
GeneOntologyMolecularFunctionchromatin binding

EOMES SRF GATA4 GATA6 HHEX TRIM37

1.19e-03739336GO:0003682
GeneOntologyMolecularFunctionzinc ion binding

GATA4 GATA6 GATA5 RNF5 MYCBP2 TRIM37

3.06e-03891336GO:0008270
GeneOntologyMolecularFunctionubiquitin protein ligase activity

RNF5 MYCBP2 TRIM37 MEX3C

3.16e-03372334GO:0061630
GeneOntologyMolecularFunctiontranscription coactivator binding

GATA4 GATA6

3.59e-0354332GO:0001223
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RNF5 MYCBP2 TRIM37 MEX3C

4.03e-03398334GO:0061659
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

HHEX FOXF2

5.01e-0364332GO:0140296
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

RNF5 MYCBP2 TRIM37 MEX3C

7.39e-03473334GO:0004842
GeneOntologyMolecularFunctionacyltransferase activity

RNF5 MYCBP2 TRIM37 CPT1C MEX3C

8.37e-03775335GO:0016746
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RNF5 MYCBP2 TRIM37 MEX3C

9.70e-03512334GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

RNF5 MYCBP2 TRIM37 MEX3C

1.11e-02532334GO:0016755
GeneOntologyMolecularFunctiontransition metal ion binding

GATA4 GATA6 GATA5 RNF5 MYCBP2 TRIM37

1.22e-021189336GO:0046914
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

EOMES SOX1 SRF GATA4 GATA6 DNAJA3 ZNF703 FOXD3 HHEX GATA5 SOX21 ZNF608 GSC TRIM37 FOXF2

8.89e-1013993315GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

EOMES SOX1 SRF GATA4 GATA6 DNAJA3 ZNF703 FOXD3 HHEX GATA5 SOX21 ZNF608 GSC TRIM37 FOXF2

1.02e-0914133315GO:1902679
GeneOntologyBiologicalProcessstem cell differentiation

EOMES SRF GATA6 DMRTA2 HHEX ALDH1A2 SOX21 GSC

2.15e-08306338GO:0048863
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

EOMES SOX1 GATA4 GATA6 DNAJA3 FOXD3 HHEX GATA5 SOX21 ZNF608 GSC TRIM37

3.85e-0810533312GO:0000122
GeneOntologyBiologicalProcessregionalization

EOMES SOX1 SRF GATA4 DMRTA2 HHEX ALDH1A2 GATA5 GSC

4.21e-08478339GO:0003002
GeneOntologyBiologicalProcesscell fate commitment

EOMES SOX1 GATA4 GATA6 HOXA13 DMRTA2 GATA5 GSC

4.65e-08338338GO:0045165
GeneOntologyBiologicalProcesspattern specification process

EOMES SOX1 SRF GATA4 DMRTA2 HHEX ALDH1A2 GATA5 GSC

9.52e-08526339GO:0007389
GeneOntologyBiologicalProcessembryonic morphogenesis

EOMES SRF GATA4 GATA6 GDF5 HOXA13 HHEX ALDH1A2 GSC FOXF2

1.03e-077133310GO:0048598
GeneOntologyBiologicalProcessembryo development

EOMES SRF GATA4 GATA6 DNAJA3 GDF5 HOXA13 FOXD3 HHEX ALDH1A2 HOXD1 GSC FOXF2

1.32e-0714373313GO:0009790
GeneOntologyBiologicalProcessdigestive tract development

GATA4 GATA6 HOXA13 ALDH1A2 GATA5 FOXF2

1.36e-07152336GO:0048565
GeneOntologyBiologicalProcessdigestive system development

GATA4 GATA6 HOXA13 ALDH1A2 GATA5 FOXF2

2.38e-07167336GO:0055123
GeneOntologyBiologicalProcessforebrain development

EOMES SOX1 SRF DMRTA2 HHEX ALDH1A2 EFNA2 GSC

7.77e-07489338GO:0030900
GeneOntologyBiologicalProcessgastrulation

EOMES SRF GATA4 GATA6 HHEX GSC

9.65e-07212336GO:0007369
GeneOntologyBiologicalProcesscell fate specification

EOMES SOX1 HOXA13 DMRTA2 GSC

1.44e-06123335GO:0001708
GeneOntologyBiologicalProcessmesenchyme development

EOMES GATA4 ZNF703 ALDH1A2 GATA5 GSC FOXF2

1.67e-06372337GO:0060485
GeneOntologyBiologicalProcessembryonic organ development

EOMES SRF GATA4 FOXD3 HHEX ALDH1A2 GSC FOXF2

2.17e-06561338GO:0048568
GeneOntologyBiologicalProcessbrain development

EOMES SOX1 SRF DMRTA2 HHEX ALDH1A2 EFNA2 SOX21 GSC

5.66e-06859339GO:0007420
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

EOMES SOX1 SRF GATA4 GATA6 HOXA13 FOXD3 HHEX GATA5 SOX21 FOXF2

6.08e-0613903311GO:0045944
GeneOntologyBiologicalProcessmesenchymal cell differentiation

EOMES ZNF703 ALDH1A2 GATA5 GSC FOXF2

6.64e-06296336GO:0048762
GeneOntologyBiologicalProcesschordate embryonic development

EOMES SRF GATA4 GATA6 FOXD3 HHEX ALDH1A2 HOXD1 GSC

8.70e-06906339GO:0043009
GeneOntologyBiologicalProcesstrophectodermal cell differentiation

EOMES SRF FOXD3

9.46e-0626333GO:0001829
GeneOntologyBiologicalProcesshead development

EOMES SOX1 SRF DMRTA2 HHEX ALDH1A2 EFNA2 SOX21 GSC

9.76e-06919339GO:0060322
GeneOntologyBiologicalProcessepithelium development

SRF GATA4 GATA6 HOXA13 ZNF703 HHEX ALDH1A2 GATA5 SOX21 GSC FOXF2

1.03e-0514693311GO:0060429
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

EOMES SRF GATA4 GATA6 FOXD3 HHEX ALDH1A2 HOXD1 GSC

1.06e-05929339GO:0009792
GeneOntologyBiologicalProcesscentral nervous system development

EOMES SOX1 SRF DMRTA2 HHEX ALDH1A2 EFNA2 SOX21 MYCBP2 GSC

1.13e-0511973310GO:0007417
GeneOntologyBiologicalProcessendoderm development

EOMES GATA4 GATA6 HHEX

1.15e-0588334GO:0007492
GeneOntologyBiologicalProcesstissue morphogenesis

EOMES SRF GATA4 HOXA13 HHEX ALDH1A2 GATA5 FOXF2

1.82e-05750338GO:0048729
GeneOntologyBiologicalProcessanimal organ morphogenesis

SOX1 SRF GATA4 GATA6 HOXA13 HHEX ALDH1A2 GATA5 GSC FOXF2

1.88e-0512693310GO:0009887
GeneOntologyBiologicalProcessheart development

EOMES SRF GATA4 GATA6 HOXA13 HHEX ALDH1A2 GATA5

1.95e-05757338GO:0007507
GeneOntologyBiologicalProcessembryonic heart tube development

SRF GATA4 HHEX ALDH1A2

2.15e-05103334GO:0035050
GeneOntologyBiologicalProcessintestinal epithelial cell differentiation

GATA4 GATA6 GATA5

2.16e-0534333GO:0060575
GeneOntologyBiologicalProcessresponse to BMP

GATA4 GATA6 GDF5 HOXA13 GATA5

2.20e-05215335GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

GATA4 GATA6 GDF5 HOXA13 GATA5

2.20e-05215335GO:0071773
GeneOntologyBiologicalProcessgastrulation with mouth forming second

SRF GATA4 HHEX

2.36e-0535333GO:0001702
GeneOntologyBiologicalProcessembryonic digestive tract development

GATA4 ALDH1A2 FOXF2

2.36e-0535333GO:0048566
GeneOntologyBiologicalProcessmuscle tissue development

EOMES SRF GATA4 GATA6 DMRTA2 ALDH1A2 GATA5

2.37e-05558337GO:0060537
GeneOntologyBiologicalProcesspositive regulation of BMP signaling pathway

GATA4 GATA6 GDF5

4.10e-0542333GO:0030513
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

GATA4 GATA6 GDF5 HOXA13 ZNF703 HHEX

4.30e-05412336GO:0090287
GeneOntologyBiologicalProcessformation of primary germ layer

EOMES SRF GATA4 GATA6

4.45e-05124334GO:0001704
GeneOntologyBiologicalProcessstem cell fate specification

DMRTA2 GSC

5.19e-057332GO:0048866
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

GATA4 GATA6 GDF5 HOXA13

5.51e-05131334GO:0030510
GeneOntologyBiologicalProcessforelimb morphogenesis

GDF5 HOXA13 ALDH1A2

6.14e-0548333GO:0035136
GeneOntologyBiologicalProcesslung development

SRF GATA4 GATA6 HHEX ALDH1A2

6.40e-05269335GO:0030324
GeneOntologyBiologicalProcessendoderm formation

EOMES GATA4 GATA6

6.54e-0549333GO:0001706
GeneOntologyBiologicalProcessrespiratory tube development

SRF GATA4 GATA6 HHEX ALDH1A2

6.86e-05273335GO:0030323
GeneOntologyBiologicalProcessolfactory bulb development

EOMES SRF EFNA2

8.28e-0553333GO:0021772
GeneOntologyBiologicalProcessatrioventricular node development

GATA4 GATA6

8.87e-059332GO:0003162
GeneOntologyBiologicalProcesscerebral cortex regionalization

EOMES DMRTA2

8.87e-059332GO:0021796
GeneOntologyBiologicalProcessolfactory lobe development

EOMES SRF EFNA2

9.76e-0556333GO:0021988
GeneOntologyBiologicalProcessrespiratory system development

SRF GATA4 GATA6 HHEX ALDH1A2

1.16e-04305335GO:0060541
GeneOntologyBiologicalProcessendocrine system development

SRF GATA6 HHEX ALDH1A2

1.23e-04161334GO:0035270
GeneOntologyBiologicalProcessstem cell fate commitment

DMRTA2 GSC

1.35e-0411332GO:0048865
GeneOntologyBiologicalProcessheart morphogenesis

SRF GATA4 GATA6 ALDH1A2 GATA5

1.47e-04321335GO:0003007
GeneOntologyBiologicalProcesscardiac muscle tissue development

SRF GATA4 GATA6 ALDH1A2 GATA5

1.60e-04327335GO:0048738
GeneOntologyBiologicalProcessprimitive streak formation

SRF HHEX

1.91e-0413332GO:0090009
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

GATA4 GATA6 GDF5 HOXA13 ZNF703

2.11e-04347335GO:0090092
GeneOntologyBiologicalProcessheart looping

SRF GATA4 ALDH1A2

2.15e-0473333GO:0001947
GeneOntologyBiologicalProcessstriated muscle tissue development

SRF GATA4 GATA6 ALDH1A2 GATA5

2.17e-04349335GO:0014706
GeneOntologyBiologicalProcessembryonic organ morphogenesis

SRF GATA4 ALDH1A2 GSC FOXF2

2.22e-04351335GO:0048562
GeneOntologyBiologicalProcessatrioventricular canal development

GATA4 GATA6

2.23e-0414332GO:0036302
GeneOntologyBiologicalProcessgland development

SRF GATA6 HOXA13 ZNF703 HHEX ALDH1A2

2.27e-04558336GO:0048732
GeneOntologyBiologicalProcesslung morphogenesis

SRF GATA4 HHEX

2.52e-0477333GO:0060425
GeneOntologyBiologicalProcessanimal organ formation

GATA6 HHEX GATA5

2.62e-0478333GO:0048645
GeneOntologyBiologicalProcessblastocyst formation

EOMES SRF FOXD3

2.62e-0478333GO:0001825
GeneOntologyBiologicalProcesstube development

SRF GATA4 GATA6 HOXA13 HHEX ALDH1A2 GATA5 GSC FOXF2

2.62e-041402339GO:0035295
GeneOntologyBiologicalProcessBMP signaling pathway

GATA4 GATA6 GDF5 HOXA13

2.66e-04197334GO:0030509
GeneOntologyBiologicalProcessdetermination of heart left/right asymmetry

SRF GATA4 ALDH1A2

2.72e-0479333GO:0061371
GeneOntologyBiologicalProcessembryonic heart tube morphogenesis

SRF GATA4 ALDH1A2

2.82e-0480333GO:0003143
GeneOntologyBiologicalProcesstelencephalon regionalization

EOMES DMRTA2

2.94e-0416332GO:0021978
GeneOntologyBiologicalProcessepithelial to mesenchymal transition

EOMES ZNF703 GSC FOXF2

2.98e-04203334GO:0001837
GeneOntologyBiologicalProcesscoronary vasculature development

SRF GATA4 GATA6

3.14e-0483333GO:0060976
GeneOntologyBiologicalProcessregulation of miRNA transcription

SRF GATA4 GATA6

3.14e-0483333GO:1902893
GeneOntologyBiologicalProcessin utero embryonic development

EOMES SRF GATA4 GATA6 FOXD3 HHEX

3.23e-04596336GO:0001701
GeneOntologyBiologicalProcessmiRNA transcription

SRF GATA4 GATA6

3.25e-0484333GO:0061614
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

GATA4 GATA6 GDF5 HOXA13 ZNF703 HHEX GATA5

3.29e-04850337GO:0071363
GeneOntologyBiologicalProcessresponse to vitamin A

GATA4 ALDH1A2

3.33e-0417332GO:0033189
GeneOntologyBiologicalProcessregulation of mesenchymal cell apoptotic process

GDF5 HOXA13

3.33e-0417332GO:2001053
GeneOntologyBiologicalProcesscardiac chamber development

SRF GATA4 GATA6 HOXA13

3.51e-04212334GO:0003205
GeneOntologyBiologicalProcessendodermal cell fate commitment

EOMES GATA6

3.74e-0418332GO:0001711
GeneOntologyBiologicalProcesscardiac vascular smooth muscle cell differentiation

SRF GATA6

3.74e-0418332GO:0060947
GeneOntologyBiologicalProcesscardioblast differentiation

EOMES SRF

3.74e-0418332GO:0010002
GeneOntologyBiologicalProcessskeletal system development

SRF GDF5 HOXA13 HOXD1 GSC MEX3C

3.82e-04615336GO:0001501
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

SRF GATA4 HOXA13 HHEX ALDH1A2 FOXF2

3.96e-04619336GO:0002009
GeneOntologyBiologicalProcesscardiocyte differentiation

EOMES SRF GATA4 GATA6

4.11e-04221334GO:0035051
GeneOntologyBiologicalProcessresponse to growth factor

GATA4 GATA6 GDF5 HOXA13 ZNF703 HHEX GATA5

4.14e-04883337GO:0070848
GeneOntologyBiologicalProcessmesenchymal cell apoptotic process

GDF5 HOXA13

4.17e-0419332GO:0097152
GeneOntologyBiologicalProcessregulation of protein ubiquitination

DNAJA3 MYCBP2 TICAM1 FOXF2

4.48e-04226334GO:0031396
GeneOntologyBiologicalProcessepithelial cell fate commitment

GATA4 HOXA13

4.63e-0420332GO:0072148
GeneOntologyBiologicalProcessskeletal muscle cell differentiation

EOMES GATA4 DMRTA2

4.82e-0496333GO:0035914
GeneOntologyBiologicalProcessdevelopmental growth

SRF GATA4 GATA6 GDF5 HHEX MYCBP2 MEX3C

5.00e-04911337GO:0048589
GeneOntologyBiologicalProcessregulation of developmental growth

SRF GATA4 GATA6 GDF5 MYCBP2

5.12e-04421335GO:0048638
GeneOntologyBiologicalProcesscellular response to gonadotropin stimulus

GATA4 GATA6

5.62e-0422332GO:0071371
GeneOntologyBiologicalProcesspancreas development

GATA6 HHEX ALDH1A2

5.75e-04102333GO:0031016
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

SRF GATA4 GATA6

5.92e-04103333GO:2000628
GeneOntologyBiologicalProcessanterior/posterior pattern specification

SRF GATA4 HHEX ALDH1A2

6.25e-04247334GO:0009952
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

GATA4 GATA6 GDF5 HOXA13 ZNF703

6.59e-04445335GO:0141091
GeneOntologyBiologicalProcessregulation of DNA-binding transcription factor activity

EOMES SRF DNAJA3 TRIM37 TICAM1

6.86e-04449335GO:0051090
GeneOntologyBiologicalProcessforebrain regionalization

EOMES DMRTA2

7.28e-0425332GO:0021871
GeneOntologyBiologicalProcessT cell differentiation in thymus

SRF DNAJA3 ZNF608

7.95e-04114333GO:0033077
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

GATA4 GATA6 GDF5

8.15e-04115333GO:0090100
GeneOntologyCellularComponentchromatin

EOMES SOX1 SRF GATA4 GATA6 HOXA13 FOXD3 DMRTA2 HHEX XPC GATA5 SOX21 HOXD1 GSC FOXF2

1.61e-0914803315GO:0000785
HumanPhenoPreauricular pit

GATA4 GATA6 GATA5 GSC

2.30e-0561154HP:0004467
HumanPhenoPeriauricular skin pits

GATA4 GATA6 GATA5 GSC

3.35e-0567154HP:0100277
HumanPhenoBranchial anomaly

GATA4 GATA6 GATA5 GSC

6.11e-0578154HP:0009794
HumanPhenoAbnormal left hemidiaphragm morphology

GATA6 ALDH1A2

8.05e-055152HP:0040046
HumanPhenoAplasia of the left hemidiaphragm

GATA6 ALDH1A2

8.05e-055152HP:0040048
HumanPhenoAplasia of the left hemidiaphragm

GATA6 ALDH1A2

8.05e-055152HP:0009112
HumanPhenoSkin pit

GATA4 GATA6 GATA5 GSC

8.18e-0584154HP:0100276
HumanPhenoUlnar deviation of the 2nd finger

GDF5 HOXA13

1.69e-047152HP:0009464
HumanPhenoAbnormal hemidiaphragm morphology

GATA6 ALDH1A2

1.69e-047152HP:0040045
HumanPhenoShortening of all middle phalanges of the fingers

GDF5 HOXA13

1.69e-047152HP:0006110
HumanPhenoDenervation of the diaphragm

GATA6 ALDH1A2

1.69e-047152HP:0009109
HumanPhenoHeart murmur

GATA4 GATA6 GATA5

1.77e-0439153HP:0030148
HumanPhenoAbnormal heart sound

GATA4 GATA6 GATA5

2.21e-0442153HP:0031657
HumanPhenoAplasia/Hypoplasia of the diaphragm

GATA6 ALDH1A2

2.88e-049152HP:0010315
HumanPhenoHypoplastic left heart

GATA4 GATA6 GATA5

3.51e-0449153HP:0004383
HumanPhenoCongenital malformation of the left heart

GATA4 GATA6 GATA5

3.95e-0451153HP:0045017
HumanPhenoLeft-to-right shunt

GATA4 GATA6

4.38e-0411152HP:0012382
HumanPhenoAbnormal periauricular region morphology

GATA4 GATA6 GATA5 GSC

4.58e-04131154HP:0000383
HumanPhenoHypoplastic heart

GATA4 GATA6 GATA5

4.68e-0454153HP:0001961
HumanPhenoSystolic heart murmur

GATA4 GATA6

6.20e-0413152HP:0031664
HumanPhenoST segment depression

GATA4 GATA6

6.20e-0413152HP:0012250
HumanPhenoIncreased pulmonary vascular resistance

GATA4 GATA6

6.20e-0413152HP:0005317
HumanPhenoUnderdeveloped supraorbital ridges

GATA4 GATA6 GATA5

7.04e-0462153HP:0009891
HumanPhenoClinodactyly of the 5th finger

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

7.97e-04420156HP:0004209
HumanPhenoClinodactyly of hands

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

8.07e-04421156HP:0001157
HumanPhenoDeviation of the 5th finger

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

8.07e-04421156HP:0009179
HumanPhenoCardiac shunt

GATA4 GATA6

8.31e-0415152HP:0001693
HumanPhenoRight ventricular dilatation

GATA4 GATA6

1.07e-0317152HP:0005133
HumanPhenoRadial deviation of finger

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

1.12e-03448156HP:0009466
HumanPhenoFinger clinodactyly

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

1.18e-03452156HP:0040019
HumanPhenoRight ventricular failure

GATA4 GATA6

1.21e-0318152HP:0001708
HumanPhenoThromboembolic stroke

GATA4 GATA6 GATA5

1.23e-0375153HP:0001727
HumanPhenoRadial deviation of the hand or of fingers of the hand

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

1.24e-03456156HP:0009485
HumanPhenoDeviation of the 2nd finger

GDF5 HOXA13

1.49e-0320152HP:0009468
HumanPhenoPseudoepiphyses

GDF5 HOXA13

1.49e-0320152HP:0010584
HumanPhenoAbnormal heart morphology

GATA4 GATA6 GATA5 TRIM37

1.64e-03184154HP:3000001
HumanPhenoAbnormal right ventricular function

GATA4 GATA6

1.65e-0321152HP:0033118
HumanPhenoAtrial flutter

GATA4 GATA6

1.65e-0321152HP:0004749
HumanPhenoAtrial fibrillation

GATA4 GATA6 GATA5

1.95e-0388153HP:0005110
HumanPhenoAbnormal 5th finger morphology

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

2.20e-03509156HP:0004207
HumanPhenoAtrial arrhythmia

GATA4 GATA6 GATA5

2.29e-0393153HP:0001692
HumanPhenoAbnormal right atrium morphology

GATA4 GATA6

2.34e-0325152HP:0025580
HumanPhenoRight atrial enlargement

GATA4 GATA6

2.34e-0325152HP:0030718
HumanPhenoSynostosis of carpal bones

GDF5 HOXA13

2.53e-0326152HP:0005048
HumanPhenoBreathing dysregulation

GATA4 GATA6

2.72e-0327152HP:0005957
HumanPhenoShort 1st metacarpal

GDF5 HOXA13

2.72e-0327152HP:0010034
HumanPhenoAbnormal hallux morphology

GATA4 GATA6 GDF5 HOXA13

2.77e-03212154HP:0001844
HumanPhenoCongenital diaphragmatic hernia

GATA4 GATA6 ALDH1A2

2.81e-03100153HP:0000776
HumanPhenoDeviation of finger

GATA4 GATA6 GDF5 HOXA13 ALDH1A2 GATA5

2.90e-03537156HP:0004097
HumanPhenoDolichocephaly

GATA4 GATA6 GATA5 TRIM37

3.12e-03219154HP:0000268
MousePhenoabnormal female urethra morphology

HOXA13 GATA5

4.16e-062292MP:0011780
MousePhenoabnormal conotruncal ridge morphology

GATA4 HHEX ALDH1A2

5.35e-0617293MP:0010585
MousePhenoabnormal conotruncus morphology

GATA4 HHEX ALDH1A2

6.41e-0618293MP:0010583
MousePhenoabnormal myocardial trabeculae morphology

GATA4 HHEX ALDH1A2 GATA5 TRIM37

1.05e-05144295MP:0002189
MousePhenoartery stenosis

GATA4 HOXA13 GATA5

5.02e-0535293MP:0006135
MousePhenoabnormal hepatic diverticulum morphology

GATA6 HHEX

1.15e-048292MP:0012234
MousePhenoabnormal liver bud morphology

GATA6 HHEX

1.15e-048292MP:0012235
MousePhenoshort perineum

HOXA13 GATA5

1.15e-048292MP:0003550
MousePhenothin ventricular wall

GATA4 HOXA13 HHEX GATA5

1.78e-04138294MP:0000280
MousePhenovascular stenosis

GATA4 HOXA13 GATA5

2.07e-0456293MP:0005412
MousePhenoabnormal pterygoid bone morphology

GSC FOXF2

2.71e-0412292MP:0004453
MousePhenoabsent mesoderm

EOMES SRF FOXD3

3.52e-0467293MP:0001683
MousePhenoabnormal heart tube morphology

GATA4 HHEX ALDH1A2

3.67e-0468293MP:0000270
MousePhenosmall embryonic epiblast

GATA6 FOXD3

4.29e-0415292MP:0011189
DomainGATA_N

GATA4 GATA6 GATA5

5.03e-093333IPR008013
DomainGATA-N

GATA4 GATA6 GATA5

5.03e-093333PF05349
DomainZnF_GATA

GATA4 GATA6 GATA5

1.09e-0612333SM00401
DomainZnf_GATA

GATA4 GATA6 GATA5

2.25e-0615333IPR000679
DomainGATA

GATA4 GATA6 GATA5

2.25e-0615333PF00320
DomainGATA_ZN_FINGER_1

GATA4 GATA6 GATA5

2.77e-0616333PS00344
DomainGATA_ZN_FINGER_2

GATA4 GATA6 GATA5

2.77e-0616333PS50114
DomainTF_GATA_4/5/6

GATA4 GATA5

3.03e-062332IPR016375
DomainSOXp

SOX1 SOX21

3.02e-055332PF12336
DomainSOX_fam

SOX1 SOX21

3.02e-055332IPR022097
Domain-

GATA4 GATA6 GATA5

1.38e-04573333.30.50.10
DomainZnf_NHR/GATA

GATA4 GATA6 GATA5

1.45e-0458333IPR013088
DomainHomeobox_CS

HOXA13 HHEX HOXD1 GSC

3.11e-04186334IPR017970
DomainHomeobox

HOXA13 HHEX HOXD1 GSC

7.39e-04234334PF00046
DomainHOMEOBOX_1

HOXA13 HHEX HOXD1 GSC

7.63e-04236334PS00027
DomainHOX

HOXA13 HHEX HOXD1 GSC

7.75e-04237334SM00389
DomainHomeobox_dom

HOXA13 HHEX HOXD1 GSC

7.99e-04239334IPR001356
DomainHOMEOBOX_2

HOXA13 HHEX HOXD1 GSC

7.99e-04239334PS50071
Domain-

HOXA13 HHEX HOXD1 GSC

1.49e-032833341.10.10.60
DomainZF_RING_1

RNF5 MYCBP2 TRIM37 MEX3C

1.65e-03291334PS00518
DomainZF_RING_2

RNF5 MYCBP2 TRIM37 MEX3C

1.80e-03298334PS50089
DomainRING

RNF5 MYCBP2 TRIM37 MEX3C

1.96e-03305334SM00184
DomainZnf_RING

RNF5 MYCBP2 TRIM37 MEX3C

2.50e-03326334IPR001841
DomainHomeodomain-like

HOXA13 HHEX HOXD1 GSC

2.67e-03332334IPR009057
DomainTF_fork_head_CS_2

FOXD3 FOXF2

2.98e-0346332IPR030456
DomainTF_fork_head_CS_1

FOXD3 FOXF2

3.11e-0347332IPR018122
DomainFORK_HEAD_3

FOXD3 FOXF2

3.38e-0349332PS50039
DomainFH

FOXD3 FOXF2

3.38e-0349332SM00339
DomainFORK_HEAD_1

FOXD3 FOXF2

3.38e-0349332PS00657
DomainFORK_HEAD_2

FOXD3 FOXF2

3.38e-0349332PS00658
DomainForkhead

FOXD3 FOXF2

3.38e-0349332PF00250
DomainFork_head_dom

FOXD3 FOXF2

3.38e-0349332IPR001766
DomainHMG_box

SOX1 SOX21

3.94e-0353332PF00505
DomainHMG_BOX_2

SOX1 SOX21

4.09e-0354332PS50118
DomainHMG

SOX1 SOX21

4.09e-0354332SM00398
Domain-

SOX1 SOX21

4.24e-03553321.10.30.10
DomainHMG_box_dom

SOX1 SOX21

5.87e-0365332IPR009071
Domain-

RNF5 MYCBP2 TRIM37 MEX3C

7.77e-034493343.30.40.10
DomainZnf_RING/FYVE/PHD

RNF5 MYCBP2 TRIM37 MEX3C

8.38e-03459334IPR013083
DomainZF_BBOX

MYCBP2 TRIM37

8.78e-0380332PS50119
DomainZnf_B-box

MYCBP2 TRIM37

8.99e-0381332IPR000315
DomainHomeobox_metazoa

HHEX HOXD1

1.10e-0290332IPR020479
PathwayREACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION

EOMES GATA6 HHEX GSC

1.89e-0910264M27208
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS

EOMES GATA6 FOXD3 HHEX GSC

2.33e-0931265M27393
PathwayREACTOME_FORMATION_OF_DEFINITIVE_ENDODERM

EOMES GATA4 GATA6 GSC

2.13e-0817264M48030
PathwayREACTOME_CARDIOGENESIS

EOMES SRF GATA4 GATA6

1.55e-0727264M48011
PathwayREACTOME_GASTRULATION

EOMES SOX1 GATA4 GATA6 GSC

3.35e-06129265M46433
PathwayWP_ENDODERM_DIFFERENTIATION

EOMES GATA4 GATA6 HHEX SOX21

5.55e-06143265M39591
PathwayWP_HEART_DEVELOPMENT

SRF GATA4 GATA6

8.02e-0546263MM15884
PathwayWP_HEART_DEVELOPMENT

SRF GATA4 GATA6

8.56e-0547263M39610
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

EOMES SOX1 SRF GATA4 GATA6 FOXD3 HHEX EFNA2 HOXD1 GSC

1.31e-0414322610M509
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

EOMES SRF GATA6 SOX21

1.66e-04153264M39546
PathwayREACTOME_GERM_LAYER_FORMATION_AT_GASTRULATION

EOMES GSC

4.37e-0417262M45017
PathwayWP_SEROTONIN_RECEPTOR_2_AND_ELKSRFGATA4_SIGNALING

SRF GATA4

6.09e-0420262M39485
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

GATA4 GATA6 GATA5

1.23e-03116263MM15715
PathwayWP_CELL_LINEAGE_MAP_FOR_NEURONAL_DIFFERENTIATION

GATA4 GATA6 FOXD3

1.78e-03132263M48110
Pubmed

A census of human transcription factors: function, expression and evolution.

EOMES SOX1 SRF GATA4 GATA6 HOXA13 FOXD3 DMRTA2 HHEX GATA5 SOX21 HOXD1 GSC FOXF2

3.20e-14908331419274049
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

EOMES SRF GATA4 GATA6 HOXA13 FOXD3 DMRTA2 GATA5 HOXD1 GSC

5.41e-11544331028473536
Pubmed

Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6.

SRF GATA4 GATA6 GATA5

4.77e-101333412606287
Pubmed

Perception of differentiation cues by GATA factors in primitive endoderm lineage determination of mouse embryonic stem cells.

GATA4 GATA6 GATA5

7.78e-10333316162334
Pubmed

Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation.

GATA4 GATA6 GATA5

7.78e-1033339566909
Pubmed

GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development.

GATA4 GATA6 GATA5

7.78e-1033339119112
Pubmed

FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart.

GATA4 GATA6 HHEX GATA5

1.58e-091733417274974
Pubmed

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.

SRF GATA4 GATA6 HHEX

2.04e-091833415929941
Pubmed

Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.

GATA4 GATA6 HHEX GATA5

2.58e-091933422589735
Pubmed

Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.

EOMES SOX1 GATA4 GATA6

2.58e-091933435988542
Pubmed

Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors.

SRF GATA4 GATA6

3.11e-09433312530967
Pubmed

Wnt2 is a direct downstream target of GATA6 during early cardiogenesis.

GATA4 GATA6 GATA5

3.11e-09433316621466
Pubmed

BMP-mediated induction of GATA4/5/6 blocks somitic responsiveness to SHH.

GATA4 GATA6 GATA5

3.11e-09433325294942
Pubmed

GATA5 interacts with GATA4 and GATA6 in outflow tract development.

GATA4 GATA6 ALDH1A2 GATA5

3.22e-092033421839733
Pubmed

Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.

GATA4 GATA6 ALDH1A2 GATA5

3.22e-092033411245568
Pubmed

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

GATA4 GATA6 GATA5 GSC

4.85e-09223349136933
Pubmed

The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities.

EOMES SOX1 FOXD3 GSC

4.85e-092233421896659
Pubmed

GATA6 is essential for embryonic development of the liver but dispensable for early heart formation.

SRF GATA4 GATA6 HHEX

8.37e-092533415767668
Pubmed

The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression.

GATA4 GATA6 GATA5

1.55e-08633315539431
Pubmed

Digits in a dish: An in vitro system to assess the molecular genetics of hand/foot development at single-cell resolution.

GDF5 HOXA13 ALDH1A2

1.55e-08633336994104
Pubmed

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart.

GATA4 ALDH1A2 GATA5

1.55e-08633314550786
Pubmed

Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling.

EOMES GATA6 HHEX GSC

1.81e-083033429168693
Pubmed

Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element.

GATA4 GATA6 GATA5

2.72e-08733315987774
Pubmed

GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.

GATA4 GATA6 GATA5

2.72e-08733318212046
Pubmed

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.

SOX1 GATA4 GATA6 GSC

3.87e-083633433230114
Pubmed

Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.

GATA4 GATA6 GATA5

4.34e-08833329197504
Pubmed

The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer.

GATA4 GATA6 GATA5

4.34e-08833314662776
Pubmed

Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.

GATA4 GATA6 GATA5

6.51e-0893339738004
Pubmed

Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis.

GATA4 GATA6 GATA5

6.51e-08933310364163
Pubmed

Deletion of exon 20 of the Familial Dysautonomia gene Ikbkap in mice causes developmental delay, cardiovascular defects, and early embryonic lethality.

SRF GATA4 GATA5

9.30e-081033322046433
Pubmed

NANOG initiates epiblast fate through the coordination of pluripotency genes expression.

GATA4 GATA6 HHEX SOX21

1.07e-074633435729116
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

EOMES SOX1 GATA4 GATA6 FOXD3 GATA5 GSC

1.24e-0742433721731673
Pubmed

The emergent landscape of the mouse gut endoderm at single-cell resolution.

GATA4 GATA6 HOXA13 HHEX

1.27e-074833430959515
Pubmed

Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice.

GATA4 GATA6 GATA5

1.28e-071133319889636
Pubmed

Pax3 and Tbx5 specify whether PDGFRα+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells.

GATA4 GATA6 GATA5

2.21e-071333324677751
Pubmed

Analysis of transcription factors expressed at the anterior mouse limb bud.

EOMES HHEX GSC

2.21e-071333328467430
Pubmed

Activin/nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark.

EOMES SOX1 GSC

2.21e-071333325805847
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

SRF GATA6 HOXA13 FOXD3 HHEX SOX21 RNF5 MEX3C

2.54e-0770933822988430
Pubmed

The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration.

GATA4 GATA6 HHEX

2.81e-071433317936262
Pubmed

A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo.

EOMES GATA4 GATA6

2.81e-071433323788624
Pubmed

The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation.

GATA4 GATA6 GATA5

2.81e-071433312149478
Pubmed

Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.

GATA4 GATA6 GATA5

3.51e-071533324650916
Pubmed

Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.

SRF GATA4 GATA6

3.51e-071533319782130
Pubmed

Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice.

GATA4 GATA6 GATA5

3.51e-071533318448675
Pubmed

GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.

EOMES GATA4 GATA6

3.51e-071533324835466
Pubmed

Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo.

EOMES HHEX GSC

4.32e-071633315215210
Pubmed

Gata6 is an important regulator of mouse pancreas development.

GATA4 GATA6 GATA5

4.32e-071633316887115
Pubmed

Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding.

GDF5 HOXA13 HOXD1

5.24e-071733324075990
Pubmed

Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation.

SRF GATA4 ALDH1A2

5.24e-071733311923206
Pubmed

The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo.

EOMES HHEX GSC

6.29e-071833312091315
Pubmed

Intrauterine Pressures Adjusted by Reichert's Membrane Are Crucial for Early Mouse Morphogenesis.

EOMES GATA6 HHEX

6.29e-071833332433954
Pubmed

Calcineurin signaling regulates neural induction through antagonizing the BMP pathway.

EOMES SOX1 GATA6

6.29e-071833324698271
Pubmed

Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns.

GATA4 GATA6 ALDH1A2

7.46e-071933320185795
Pubmed

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer.

GATA4 GATA5

8.73e-07233214612389
Pubmed

Involvement of GATA-4/-5 transcription factors in ovarian carcinogenesis.

GATA4 GATA5

8.73e-07233216337738
Pubmed

Probing GATA factor function in mouse Leydig cells via testicular injection of adenoviral vectors.

GATA4 GATA6

8.73e-07233228710293
Pubmed

Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators.

SRF GATA4

8.73e-07233211003651
Pubmed

Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types.

GATA4 GATA5

8.73e-07233217912029
Pubmed

Differential expression of GATA-4 and GATA-6 in fetal and adult mouse and human adrenal tissue.

GATA4 GATA6

8.73e-07233212130579
Pubmed

Loss of GATA4 and GATA6 expression specifies ovarian cancer histological subtypes and precedes neoplastic transformation of ovarian surface epithelia.

GATA4 GATA6

8.73e-07233219649254
Pubmed

Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis.

GATA4 GATA6

8.73e-07233233876316
Pubmed

Serum response factor-GATA ternary complex required for nuclear signaling by a G-protein-coupled receptor.

SRF GATA4

8.73e-07233211158291
Pubmed

Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.

GATA4 GATA6

8.73e-07233228196600
Pubmed

GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm.

GATA4 GATA6

8.73e-0723328660897
Pubmed

GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.

GATA4 GATA5

8.73e-07233219509152
Pubmed

Hypermethylation of the GATA gene family in esophageal cancer.

GATA4 GATA5

8.73e-07233216823849
Pubmed

Methylation of GATA-4 and GATA-5 and development of sporadic gastric carcinomas.

GATA4 GATA5

8.73e-07233220222162
Pubmed

Hypermethylation of the GATA genes in lung cancer.

GATA4 GATA5

8.73e-07233215585625
Pubmed

Parsing the roles of the transcription factors GATA-4 and GATA-6 in the adult cardiac hypertrophic response.

GATA4 GATA6

8.73e-07233224391969
Pubmed

HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.

EOMES HHEX

8.73e-07233224651531
Pubmed

Genetic variations in the transcription factors GATA4 and GATA6 and bleeding complications in patients receiving warfarin therapy.

GATA4 GATA6

8.73e-07233231190750
Pubmed

GATA-4 and GATA-6 expression in human ovarian surface epithelial carcinoma.

GATA4 GATA6

8.73e-07233218227727
Pubmed

Differentiation of embryonic stem cells is induced by GATA factors.

GATA4 GATA6

8.73e-07233211937486
Pubmed

The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo.

GATA4 GATA6

8.73e-07233211356841
Pubmed

Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells.

GATA4 GATA6

8.73e-07233217605826
Pubmed

Variants in cardiac GATA genes associated with bicuspid aortic valve.

GATA4 GATA5

8.73e-07233230229885
Pubmed

Transcription factors GATA-4 and GATA-6 during mouse and human adrenocortical development.

GATA4 GATA6

8.73e-07233212530677
Pubmed

Transcription factors GATA-4 and GATA-6, and their potential downstream effectors in ovarian germ cell tumors.

GATA4 GATA6

8.73e-07233216110260
Pubmed

Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa.

GATA4 GATA6

8.73e-07233218405344
Pubmed

GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice.

GATA4 GATA6

8.73e-07233221262227
Pubmed

Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility.

GATA4 GATA6

8.73e-07233222434075
Pubmed

Piceatannol attenuates cardiac hypertrophy in an animal model through regulation of the expression and binding of the transcription factor GATA binding factor 6.

GATA4 GATA6

8.73e-07233224662306
Pubmed

Expression and hormonal regulation of transcription factors GATA-4 and GATA-6 in the mouse ovary.

GATA4 GATA6

8.73e-0723329231805
Pubmed

Transcription factors GATA-4 and GATA-6 in human adrenocortical tumors.

GATA4 GATA6

8.73e-07233215666845
Pubmed

HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst.

EOMES GATA4 GATA6

8.77e-072033325340657
Pubmed

HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo.

SOX1 HHEX GSC

8.77e-072033310498685
Pubmed

Extraembryonic proteases regulate Nodal signalling during gastrulation.

EOMES HHEX GSC

1.02e-062133312447384
Pubmed

Embryo model completes gastrulation to neurulation and organogenesis.

SOX1 GATA4 GATA6

1.18e-062233336007540
Pubmed

Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo.

EOMES FOXD3 HHEX

1.18e-062233312381664
Pubmed

Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation.

GATA4 GATA6 ALDH1A2

1.36e-062333315766748
Pubmed

Morphogenesis of the right ventricle requires myocardial expression of Gata4.

GATA4 GATA6 GATA5

1.36e-062333315902305
Pubmed

Generation of mice with functional inactivation of talpid3, a gene first identified in chicken.

GDF5 HOXA13 ALDH1A2

1.36e-062333321750036
Pubmed

Disruption of early proximodistal patterning and AVE formation in Apc mutants.

EOMES HHEX GSC

1.36e-062333316887818
Pubmed

Loss of Gata5 in mice leads to bicuspid aortic valve.

GATA4 GATA6 GATA5

1.55e-062433321633169
Pubmed

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

SOX1 GATA4 HHEX

1.55e-062433321149574
Pubmed

Ets2-dependent trophoblast signalling is required for gastrulation progression after primitive streak initiation.

EOMES HHEX GSC

1.55e-062433323552073
Pubmed

Crucial role of vHNF1 in vertebrate hepatic specification.

GATA4 GATA6 HHEX

1.55e-062433318635606
Pubmed

FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium.

GATA4 GATA6 ALDH1A2

1.55e-062433310892744
Pubmed

Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome.

GATA4 GATA6 ALDH1A2

1.76e-062533329509905
Pubmed

GATA6 is a crucial regulator of Shh in the limb bud.

GATA4 GATA6 GATA5

1.99e-062633324415953
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATA4 GATA6 GATA5

1.05e-061525382
GeneFamilySRY-boxes

SOX1 SOX21

3.09e-0419252757
GeneFamilyForkhead boxes

FOXD3 FOXF2

1.60e-0343252508
GeneFamilyHOXL subclass homeoboxes

HOXA13 HOXD1

2.33e-0352252518
GeneFamilyRing finger proteins

RNF5 TRIM37 MEX3C

6.25e-0327525358
CoexpressionBENPORATH_SUZ12_TARGETS

EOMES SOX1 GATA4 GATA6 ZNF703 FOXD3 HHEX GATA5 SOX21 HOXD1 GSC

3.00e-0810353311M9898
CoexpressionBENPORATH_EED_TARGETS

EOMES SOX1 GATA4 GATA6 HOXA13 FOXD3 HHEX SOX21 HOXD1 GSC FOXF2

3.80e-0810593311M7617
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

GATA4 HOXA13 FOXD3 GATA5 HOXD1 GSC

1.03e-06272336M1938
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

GATA4 HOXA13 FOXD3 GATA5 HOXD1 GSC

1.28e-06282336MM822
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

GATA6 HOXA13 FOXD3 ALDH1A2 HOXD1 FOXF2

4.44e-06350336M1949
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

GATA6 HOXA13 FOXD3 ALDH1A2 HOXD1 FOXF2

4.97e-06357336MM828
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

EOMES SOX1 GATA6 HOXD1 FOXF2

6.22e-06210335M2010
CoexpressionBENPORATH_ES_WITH_H3K27ME3

EOMES GATA4 GATA6 HOXA13 FOXD3 HHEX HOXD1 GSC FOXF2

6.76e-061115339M10371
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

EOMES SOX1 GATA6 HOXD1 FOXF2

7.30e-06217335MM861
CoexpressionBENPORATH_PRC2_TARGETS

EOMES GATA4 GATA6 FOXD3 HHEX HOXD1 GSC

1.36e-05650337M8448
CoexpressionMCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER

GATA4 GATA5 HOXD1

2.02e-0542333M8760
CoexpressionESC_V6.5_UP_LATE.V1_UP

EOMES GATA4 GATA6 GSC

8.20e-05184334M2772
CoexpressionYEMELYANOV_GR_TARGETS_DN

SRF GATA4

8.39e-0511332M17211
CoexpressionGSE17721_0.5H_VS_8H_LPS_BMDC_UP

SRF ZNF703 HHEX XPC

1.11e-04199334M4074
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

GATA4 FOXD3 GATA5 EFNA2 MYCBP2

2.05e-04438335M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

GATA4 FOXD3 GATA5 EFNA2 MYCBP2

2.10e-04440335MM832
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

SOX1 GATA6 DMRTA2 HHEX ALDH1A2 SOX21 FOXF2

3.19e-041074337M1941
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_100

EOMES GATA4 GATA6 HHEX GSC

4.26e-0799335PCBC_ratio_DE_vs_SC_100
CoexpressionAtlasratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_100

EOMES GATA4 GATA6 HHEX GSC

4.26e-0799335PCBC_ratio_MESO-5_vs_SC_100
CoexpressionAtlasratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_500

EOMES GATA4 GATA6 ZNF703 DMRTA2 HHEX GATA5 GSC

6.85e-07495338PCBC_ratio_MESO-5_vs_SC_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_500

EOMES GATA4 GATA6 FOXD3 EFNA2 GSC A2ML1

8.71e-06492337PCBC_DE_fibroblast_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_100

GATA6 HOXA13 GATA5 FOXF2

9.38e-0686334gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_500

GATA6 HOXA13 ALG11 ALDH1A2 GATA5 FOXF2

4.18e-05422336DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_200

GATA6 GATA5 FOXF2

6.00e-0549333gudmap_developingLowerUrinaryTract_e14.5_ bladder_200_k1
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500

EOMES GATA4 GATA6 EFNA2 GSC A2ML1

9.44e-05489336PCBC_MESO-5_fibroblast_500
CoexpressionAtlasratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#3

ZNF703 DMRTA2 GATA5

9.45e-0557333ratio_MESO_vs_SC_500_K3
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_1000

EOMES GATA4 GATA6 DMRTA2 GATA5 EFNA2 GSC A2ML1

9.49e-05974338PCBC_MESO-5_1000
CoexpressionAtlasmendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K3

SRF GATA6 HOXA13 ZNF703 TMEM256 ALDH1A2 GATA5 HOXD1 RNF5

9.68e-051266339mendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K3
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_1000

EOMES GATA4 GATA6 FOXD3 HHEX EFNA2 GSC A2ML1

9.70e-05977338PCBC_DE_fibroblast_1000
CoexpressionAtlasratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000

EOMES GATA4 GATA6 ZNF703 DMRTA2 HHEX GATA5 GSC

1.00e-04982338PCBC_ratio_MESO-5_vs_SC_1000
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500

GATA4 GATA6 ZNF703 ALDH1A2 GATA5 FOXF2

1.04e-04498336PCBC_ratio_EB_vs_SC_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_200

HOXA13 ALDH1A2 HOXD1 FOXF2

1.21e-04165334gudmap_developingLowerUrinaryTract_e14.5_ urethra_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_200

GATA6 HOXA13 GATA5 FOXF2

1.24e-04166334gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_200

HOXA13 GATA5 HOXD1 FOXF2

1.24e-04166334gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_200

HOXA13 ALDH1A2 HOXD1 FOXF2

1.29e-04168334gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_200

HOXA13 ALDH1A2 HOXD1 FOXF2

1.35e-04170334DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_200

GATA6 ALG11 GATA5 FOXF2

1.38e-04171334gudmap_developingLowerUrinaryTract_e14.5_ bladder_200
CoexpressionAtlase10.5_MandibArch_top-relative-expression-ranked_100

HHEX GSC FOXF2

1.46e-0466333Facebase_ST1_e10.5_MandibArch_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

HOXA13 ALG11 ALDH1A2 GATA5 HOXD1 MYCBP2 FOXF2

1.99e-04806337gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

GATA6 HOXA13 ALG11 HHEX ALDH1A2 GATA5 FOXF2

2.07e-04811337gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_100

GATA4 GATA6 ALDH1A2

2.14e-0475333gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000

GATA6 HOXA13 ALG11 HHEX ALDH1A2 GATA5 FOXF2

2.31e-04826337DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_100

GATA4 GATA6 ALDH1A2

2.79e-0482333gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_100

HOXA13 FOXF2

3.14e-0417332DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_100

HOXA13 HOXD1 FOXF2

3.21e-0486333gudmap_developingLowerUrinaryTract_e14.5_ urethra_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_100

HOXA13 HOXD1 FOXF2

3.55e-0489333DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_100

HOXA13 HOXD1 FOXF2

3.55e-0489333DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_500

HOXA13 ALDH1A2 SOX21 HOXD1 FOXF2

3.60e-04401335gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500
CoexpressionAtlasMesoderm Day 5-reprogram_NA_vs_Mesoderm Day 5-reprogram_OSK-L-l-p53KD-Confounder_removed-fold2.0_adjp0.05

GATA6 HHEX GSC

3.91e-0492333PCBC_ratio_MESO-5_from-ESC_vs_MESO-5_from-OSK-L-l-p53KD_cfr-2X-p05
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500

GATA6 HOXA13 ALG11 GATA5 FOXF2

4.49e-04421335gudmap_developingLowerUrinaryTract_e14.5_ bladder_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_100

EOMES GATA4 GSC

4.70e-0498333PCBC_MESO-5_fibroblast_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_100

EOMES GATA4 GSC

4.70e-0498333PCBC_MESO-5_100
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500

SRF GATA4 GATA6 ALDH1A2 MEX3C

5.05e-04432335gudmap_dev gonad_e11.5_M_GonMes_Sma_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

EOMES GATA4 GATA6 HHEX EFNA2 GSC A2ML1

6.08e-04969337PCBC_MESO-5_blastocyst_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

EOMES GATA4 GATA6 HHEX EFNA2 GSC A2ML1

6.08e-04969337PCBC_MESO-5_fibroblast_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_1000

EOMES GATA4 GATA6 FOXD3 EFNA2 GSC A2ML1

6.54e-04981337PCBC_DE_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_1000

EOMES GATA4 GATA6 FOXD3 EFNA2 GSC A2ML1

6.54e-04981337PCBC_DE_blastocyst_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_100

HOXA13 FOXF2

6.87e-0425332DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_100
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

GATA4 ALDH1A2 MEX3C

6.94e-04112333gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k1_1000
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000

GATA4 GATA6 HOXA13 ZNF703 ALDH1A2 GATA5 FOXF2

7.07e-04994337PCBC_ratio_EB_vs_SC_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500

EOMES GATA4 GATA6 GSC A2ML1

8.06e-04479335PCBC_MESO-5_blastocyst_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000

HOXA13 XPC SOX21 HOXD1

8.49e-04276334gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k3
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromBlastocyst-derived-iPSC_top-relative-expression-ranked_500

EOMES GATA4 GATA6 FOXD3 GSC

9.00e-04491335PCBC_DE_blastocyst_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Mesoderm_top-relative-expression-ranked_500

EOMES GATA4 GATA6 GSC A2ML1

9.00e-04491335PCBC_MESO-5_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_1000

GATA6 HHEX GATA5

9.33e-04124333gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k1
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500

EOMES GATA4 GATA6 HHEX GSC

9.34e-04495335PCBC_ratio_DE_vs_SC_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-DefinitiveEndoderm_top-relative-expression-ranked_500

EOMES GATA4 GATA6 FOXD3 GSC

9.42e-04496335PCBC_DE_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

GATA4 GATA6 ALDH1A2

9.55e-04125333gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k1_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_100

GATA6 GATA5

9.91e-0430332gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_100_k4
CoexpressionAtlasratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1

EOMES GATA4 GATA6 GSC

1.07e-03294334ratio_MESO_vs_SC_500_K1
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#2

EOMES GATA4 GATA6 HHEX GSC

1.08e-03511335ratio_DE_vs_SC_1000_K2
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#5

EOMES GATA4 GATA6 GSC

1.11e-03297334ratio_DE_vs_SC_500_K5
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_100

GATA4 GATA6

1.13e-0332332gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_200

ALDH1A2 HOXD1

1.20e-0333332DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_200
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5

EOMES GATA4 GATA6 HHEX GSC

1.26e-03529335ratio_DE_vs_SC_1000_K5
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#3_top-relative-expression-ranked_1000

GATA5 MYCBP2

1.27e-0334332gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000

HOXA13 XPC ALDH1A2 SOX21 HOXD1 FOXF2

1.30e-03800336gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000

HOXA13 ALG11 ALDH1A2 HOXD1 MYCBP2 FOXF2

1.35e-03806336DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_200

GATA4 GATA6 ALDH1A2

1.41e-03143333gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_200
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#3

TMEM256 FOXD3 ALDH1A2

1.41e-03143333Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_200

HOXA13 FOXF2

1.51e-0337332gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_200_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#5_top-relative-expression-ranked_1000

GATA6 HHEX ALDH1A2 GATA5

1.52e-03323334gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_1000

GATA6 HOXA13 HHEX ALDH1A2 GATA5 FOXF2

1.64e-03837336gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_200

ALDH1A2 HOXD1

1.67e-0339332gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k4
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_200

GATA4 GATA6 ALDH1A2

1.68e-03152333gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_200
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1

HOXA13 ZNF703 ALDH1A2 FOXF2

1.75e-03336334ratio_EB_vs_SC_1000_K1
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#4_top-relative-expression-ranked_200

GATA4 MEX3C

1.76e-0340332gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k4_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_200

GATA4 GATA6 ALDH1A2

1.87e-03158333gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_200
CoexpressionAtlase10.5_MandibArch_top-relative-expression-ranked_250

HHEX GSC FOXF2

1.94e-03160333Facebase_ST1_e10.5_MandibArch_250
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_200

GATA4 GATA6 ALDH1A2

1.98e-03161333gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_200
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200

GATA4 GATA6 ALDH1A2

2.01e-03162333gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1

ZNF703 GATD3 ALDH1A2 GSC FOXF2

2.01e-03589335Facebase_RNAseq_e9.5_Maxillary Arch_2500_K1
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_200

GATA4 GATA6 MEX3C

2.08e-03164333gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_200
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_200

GATA4 GATA6 ALDH1A2

2.12e-03165333gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_1000

GATA6 HHEX GATA5

2.23e-03168333DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_200

HOXA13 GATA5 FOXF2

2.27e-03169333DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_200

HOXA13 FOXF2

2.32e-0346332DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_200
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_500

GATA4 ALDH1A2

2.32e-0346332gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k3_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500

GATA4 GATA6

2.32e-0346332gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_500
ToppCellHippocampus-Macroglia|Hippocampus / BrainAtlas - Mouse McCarroll V32

TMEM256 DMRTA2 SOX21 RNF5

1.01e-05184334a1d039ddf1e2a87b870f3ce6d139be56090349df
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GATA4 GATA6 ALDH1A2 GATA5

1.24e-05194334f4286ae7bb8350c42d50727ee8688b80129714f6
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GATA4 GATA6 ALDH1A2 GATA5

1.24e-0519433487461bd6d7f702c0a0f5e0c8ace3049125a51f9a
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GATA4 GATA6 ALDH1A2 GATA5

1.24e-05194334c578cf7c6b4d6f31f87dde8845de5b3891f16822
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EOMES GDF5 DMRTA2

3.17e-05833331ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EOMES GDF5 DMRTA2

3.17e-058333375b27d91a4473286f4b40027e96ac5246f5abe5b
DrugCosopt

SRF GATA4 GATA6 HHEX GATA5 EFNA2 GSC

4.86e-07341337CID000003154
DrugDMEQ-COCl

HHEX TRIM37

6.11e-063332CID000147056
Drugpemirolast

SRF GATA4 ALDH1A2 GSC

6.20e-0683334CID000057697
DrugAC1L9Q5W

GDF5 HOXA13 HHEX ALDH1A2

1.64e-05106334CID000452221
Drugp-tolylhydrazine

HHEX TRIM37

2.03e-055332CID000010875
DrugH 238

HHEX TRIM37

5.67e-058332CID000012089
Drughydron;propane-1,3-diol

GATA4 GATA6 GATA5

8.11e-0558333CID005288578
Drugbis-diazotized benzidine

TRIM37 A2ML1

9.10e-0510332CID000192775
Diseasetetralogy of Fallot (is_implicated_in)

GATA4 GATA6 GATA5

3.62e-0713333DOID:6419 (is_implicated_in)
Diseaseventricular septal defect (is_implicated_in)

GATA4 GATA6 GATA5

4.60e-0714333DOID:1657 (is_implicated_in)
DiseaseTetralogy of Fallot

GATA4 GATA6 GATA5

7.07e-0716333C0039685
DiseaseATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)

GATA4 GATA6 GATA5

1.93e-0622333C1843687
DiseaseATRIOVENTRICULAR CANAL DEFECT

GATA4 GATA6

3.64e-063332C1389016
DiseaseAtrioventricular Septal Defect

GATA4 GATA6

3.64e-063332C1389018
Diseaseatrioventricular septal defect (is_implicated_in)

GATA4 GATA6

3.64e-063332DOID:0050651 (is_implicated_in)
DiseaseFamilial atrioventricular septal defect

GATA4 GATA6

7.27e-064332cv:CN029142
DiseasePartial atrioventricular canal

GATA4 GATA6

7.27e-064332C0344735
DiseaseTetralogy of Fallot

GATA4 GATA6

1.81e-056332cv:C0039685
DiseaseTETRALOGY OF FALLOT

GATA4 GATA6

1.81e-056332187500
DiseaseOstium secundum atrial septal defect

GATA4 GATA6

4.35e-059332C0344724
DiseaseCongenital diaphragmatic hernia

GATA4 GATA6

2.51e-0421332C0235833
Diseasecongenital heart disease (is_implicated_in)

GATA4 GATA6

3.30e-0424332DOID:1682 (is_implicated_in)
DiseaseNeonatal diabetes mellitus

GATA4 GATA6

3.58e-0425332C0158981
Diseaselower urinary tract symptom, benign prostatic hyperplasia

GATA6 GATA5

5.89e-0432332EFO_0000284, EFO_0008008
Diseasetriglyceride measurement, physical activity

GATA4 ALDH1A2

6.65e-0434332EFO_0003940, EFO_0004530
DiseaseDiuretic use measurement

GATA4 HOXA13 MEX3C

8.87e-04169333EFO_0009928
DiseaseDiaphragmatic Hernia

GATA4 GATA6

9.68e-0441332C0019284
Diseaseerectile dysfunction

DNAJA3 FOXF2

1.02e-0342332EFO_0004234

Protein segments in the cluster

PeptideGeneStartEntry
AFFHPYCNAGGGGER

ALG11

66

Q2TAA5
GAHFYPLESARGGSG

EOMES

16

O95936
GYGPTAGAAIASHIG

ALDH1A2

241

O94788
YSTAMGAGGGHPEAF

A2ML1

701

A8K2U0
SHFGADAGAYPLGAP

DMRTA2

446

Q96SC8
NVFRPGGHSYGGGAT

GDF5

56

P43026
APAAAAGGADYGFLG

HOXD1

96

Q9GZZ0
HHSAAALAAAYGPGG

HHEX

81

Q03014
ANHDAAIFPGGFGAA

GATD3B

126

A0A0B4J2D5
DYVSSGGGFGPADDH

CPT1C

701

Q8TCG5
GAYEAGGPGAFMHGA

GATA4

16

P43694
YADSGSFLHAPGAGS

GATA5

16

Q9BWX5
AYDGAPGGFVHSAAA

GATA6

161

Q92908
PRFHAGAGDDGGGYT

EFNA2

46

O43921
ANHDAAIFPGGFGAA

GATD3

126

P0DPI2
PALHGDSLYGASGGA

GSC

36

P56915
AYGSAGFDPGASGSQ

DNAJA3

156

Q96EY1
FGAYSLAAAAGAAGP

FOXD3

256

Q9UJU5
AGYDAGAGAPSHAHP

FOXF2

251

Q12947
EDAAAAGPAGSSHGY

TRIM37

576

O94972
GYPTAGAGAFHGAAA

SOX21

196

Q9Y651
DTGGFHFSFGVGAFP

RNF5

116

Q99942
LSHAYGPGGCGAAAA

MEX3C

201

Q5U5Q3
AAASSGLGGDGFYPA

MYCBP2

11

O75592
ESPGGAAGGGYAHVN

SOX1

171

O00570
GGFPHPAAAAAGGNF

HOXA13

56

P31271
ASAAATGGYGPVSGA

SRF

116

P11831
GAAALGFASYGAHGA

TMEM256

16

Q8N2U0
GFASYGAHGAQFPDA

TMEM256

21

Q8N2U0
AYPGASGLGSAAAAA

ZNF703

496

Q9H7S9
FGSHMSFGTGAPYGA

TICAM1

591

Q8IUC6
ARSGAAYGPGAHGED

TSPAN10

321

Q9H1Z9
GSQAPSGGHLYGFGA

ZNF608

226

Q9ULD9
GFDFHGGYSHPVTDG

XPC

796

Q01831
AGGAGYSHADLAGVP

TIMM23

21

O14925