Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneurexin family protein binding

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.92e-0916845GO:0042043
GeneOntologyMolecularFunctionoxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor

GMPR GMPR2

1.75e-052842GO:0046857
GeneOntologyMolecularFunctionGMP reductase activity

GMPR GMPR2

1.75e-052842GO:0003920
GeneOntologyMolecularFunctionchloride ion binding

NLGN4X NLGN4Y WNK4

3.87e-0516843GO:0031404
GeneOntologyMolecularFunctionglycerol-3-phosphate O-acyltransferase activity

GPAT3 GPAT4

1.73e-045842GO:0004366
GeneOntologyMolecularFunctionscaffold protein binding

NLGN3 NLGN4X NLGN4Y NLGN1

6.40e-0493844GO:0097110
GeneOntologyBiologicalProcesspresynaptic membrane assembly

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

2.46e-1010845GO:0097105
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.50e-1011845GO:0097104
GeneOntologyBiologicalProcesspresynaptic membrane organization

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

1.25e-0913845GO:0097090
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.19e-0916845GO:0007158
GeneOntologyBiologicalProcesspostsynaptic membrane organization

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.22e-0656845GO:0001941
GeneOntologyBiologicalProcesspositive regulation of protein localization to synapse

NLGN3 NLGN2 NLGN1

3.60e-068843GO:1902474
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle clustering

NLGN3 NLGN2 NLGN1

3.60e-068843GO:2000809
GeneOntologyBiologicalProcesspresynapse assembly

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.55e-0660845GO:0099054
GeneOntologyBiologicalProcessterminal button organization

NLGN3 NLGN2 NLGN1

5.38e-069843GO:0072553
GeneOntologyBiologicalProcessmembrane assembly

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

6.27e-0664845GO:0071709
GeneOntologyBiologicalProcessmembrane biogenesis

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

1.20e-0573845GO:0044091
GeneOntologyBiologicalProcesspresynapse organization

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

1.20e-0573845GO:0099172
GeneOntologyBiologicalProcesssocial behavior

NLGN3 PTCHD1 NLGN4X NLGN4Y NLGN2

1.28e-0574845GO:0035176
GeneOntologyBiologicalProcessregulation of synaptic vesicle clustering

NLGN3 NLGN2 NLGN1

1.40e-0512843GO:2000807
GeneOntologyBiologicalProcessbiological process involved in intraspecies interaction between organisms

NLGN3 PTCHD1 NLGN4X NLGN4Y NLGN2

1.46e-0576845GO:0051703
GeneOntologyBiologicalProcessregulation of respiratory gaseous exchange by nervous system process

NLGN3 NLGN2 NLGN1

2.30e-0514843GO:0002087
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission, glutamatergic

NLGN3 GLUL NLGN2 NLGN1

2.80e-0543844GO:0051968
GeneOntologyBiologicalProcesspostsynapse assembly

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.90e-0593845GO:0099068
GeneOntologyBiologicalProcessregulation of respiratory system process

NLGN3 NLGN2 NLGN1

4.25e-0517843GO:0044065
GeneOntologyBiologicalProcesssynaptic vesicle endocytosis

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.54e-0596845GO:0048488
GeneOntologyBiologicalProcessterritorial aggressive behavior

NLGN4X NLGN4Y

4.90e-053842GO:0002124
GeneOntologyBiologicalProcesspresynaptic endocytosis

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

6.07e-05102845GO:0140238
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

CDH24 DSG1 NLGN1 CDH18

6.44e-0553844GO:0016339
GeneOntologyBiologicalProcesssynaptic vesicle recycling

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

9.08e-05111845GO:0036465
GeneOntologyBiologicalProcesssynaptic vesicle clustering

NLGN3 NLGN2 NLGN1

9.49e-0522843GO:0097091
GeneOntologyBiologicalProcessmale courtship behavior

NLGN4X NLGN4Y

9.78e-054842GO:0008049
GeneOntologyBiologicalProcessvocalization behavior

NLGN3 NLGN4X NLGN4Y

1.24e-0424843GO:0071625
GeneOntologyBiologicalProcessregulation of AMPA receptor activity

NLGN3 NLGN2 NLGN1

1.40e-0425843GO:2000311
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

NLGN3 NLGN4X NLGN2 NLGN1

1.43e-0465844GO:0098815
GeneOntologyBiologicalProcessregulation of respiratory gaseous exchange

NLGN3 NLGN2 NLGN1

1.78e-0427843GO:0043576
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

NLGN3 NLGN2 NLGN1

1.78e-0427843GO:0060080
GeneOntologyBiologicalProcesscourtship behavior

NLGN4X NLGN4Y

3.40e-047842GO:0007619
GeneOntologyBiologicalProcessimport into cell

NLGN3 SUSD4 NLGN4X NLGN4Y CDC42SE1 SLC22A2 HGS SLC38A5 NLGN2 NLGN1 SLC12A7 WNK4 ALOX15

3.85e-0410748413GO:0098657
GeneOntologyBiologicalProcesscell-cell adhesion

CITED2 NLGN3 CDH24 TENM4 NLGN4X DSG1 NLGN4Y HSPH1 LRRC7 NLGN2 NLGN1 ALOX15 CDH18

3.96e-0410778413GO:0098609
GeneOntologyBiologicalProcessnegative regulation of dendritic spine morphogenesis

NLGN3 NLGN1

4.52e-048842GO:0061002
GeneOntologyBiologicalProcessbrainstem development

NLGN4X NLGN4Y

4.52e-048842GO:0003360
GeneOntologyBiologicalProcessregulation of protein localization to synapse

NLGN3 NLGN2 NLGN1

4.96e-0438843GO:1902473
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

NLGN3 GLUL NLGN2 NLGN1

5.45e-0492844GO:0051966
GeneOntologyBiologicalProcessIMP salvage

GMPR GMPR2

5.79e-049842GO:0032264
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

NLGN3 NLGN2 NLGN1

7.15e-0443843GO:2000463
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

NLGN3 NLGN2

7.22e-0410842GO:0097151
GeneOntologyBiologicalProcessregulation of nervous system process

NLGN3 TENM4 NLGN4X NLGN2 NLGN1

7.46e-04175845GO:0031644
GeneOntologyBiologicalProcesspostsynaptic specialization assembly

NLGN3 NLGN2 NLGN1

7.65e-0444843GO:0098698
GeneOntologyBiologicalProcessregulation of presynapse organization

NLGN3 NLGN2 NLGN1

8.72e-0446843GO:0099174
GeneOntologyBiologicalProcesspostsynaptic density protein 95 clustering

NLGN2 NLGN1

8.80e-0411842GO:0097119
GeneOntologyBiologicalProcessmodulation of inhibitory postsynaptic potential

NLGN3 NLGN2

1.05e-0312842GO:0098828
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN3 NLGN4X NLGN4Y NLGN2

2.67e-104864GO:0098983
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

C1QL1 NLGN3 NLGN4X NLGN4Y NLGN1

4.19e-0824865GO:0098985
GeneOntologyCellularComponentinhibitory synapse

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

1.64e-0731865GO:0060077
GeneOntologyCellularComponentsymmetric synapse

NLGN3 NLGN4X NLGN4Y NLGN2

1.86e-0713864GO:0032280
GeneOntologyCellularComponentexcitatory synapse

C1QL1 NLGN3 SUSD4 NLGN4X NLGN4Y NLGN2 NLGN1

2.91e-07107867GO:0060076
GeneOntologyCellularComponentGMP reductase complex

GMPR GMPR2

1.67e-052862GO:1902560
GeneOntologyCellularComponentglycinergic synapse

NLGN4X NLGN4Y NLGN2

7.29e-0520863GO:0098690
GeneOntologyCellularComponentsupraspliceosomal complex

RBMXL1 RBMX

9.98e-054862GO:0044530
GeneOntologyCellularComponentpostsynaptic specialization membrane

NLGN3 NLGN4X NLGN4Y LRRC7 NLGN2 NLGN1

1.82e-04201866GO:0099634
GeneOntologyCellularComponentGABA-ergic synapse

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

5.84e-04164865GO:0098982
GeneOntologyCellularComponentmitochondrial nucleoid

ATAD3B ATAD3C ATAD3A

1.21e-0351863GO:0042645
GeneOntologyCellularComponentnucleoid

ATAD3B ATAD3C ATAD3A

1.21e-0351863GO:0009295
GeneOntologyCellularComponentneuron to neuron synapse

C1QL1 NLGN3 NLGN4X NLGN4Y RBMX LRRC7 NLGN2 NLGN1

1.40e-03523868GO:0098984
GeneOntologyCellularComponentpostsynaptic membrane

NLGN3 SUSD4 NLGN4X NLGN4Y LRRC7 NLGN2 NLGN1

1.41e-03405867GO:0045211
GeneOntologyCellularComponentsynaptic membrane

NLGN3 SUSD4 NLGN4X NLGN4Y SLC22A2 LRRC7 NLGN2 NLGN1

2.75e-03583868GO:0097060
MousePhenosmall embryonic epiblast

ATAD3B ATAD3C ATAD3A EXOSC2

5.59e-0715654MP:0011189
MousePhenoabsent ectoplacental cone

ATAD3B ATAD3C ATAD3A

7.90e-069653MP:0001717
MousePhenoabnormal proximal-distal axis patterning

ATAD3B ATAD3C ATAD3A

2.65e-0513653MP:0001705
MousePhenoabsent extraembryonic ectoderm

ATAD3B ATAD3C ATAD3A

4.20e-0515653MP:0002583
DomainNlgn

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

1.63e-125845IPR000460
DomainCarboxylesterase_B_CS

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

2.04e-0913845IPR019819
DomainCARBOXYLESTERASE_B_2

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.16e-0914845PS00941
DomainCOesterase

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.16e-0914845PF00135
DomainCarbesteraseB

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.16e-0914845IPR002018
DomainDUF3523

ATAD3B ATAD3C ATAD3A

8.78e-083843PF12037
DomainDUF3523

ATAD3B ATAD3C ATAD3A

8.78e-083843IPR021911
Domain-

NLGN3 NLGN4X LYPLAL1 NLGN4Y NLGN2 NLGN1

1.60e-051198463.40.50.1820
DomainAB_hydrolase

NLGN3 NLGN4X LYPLAL1 NLGN4Y NLGN2 NLGN1

1.60e-05119846IPR029058
DomainNLGN4

NLGN4X NLGN4Y

2.00e-052842IPR030025
DomainGMPR

GMPR GMPR2

2.00e-052842IPR005993
DomainIMPDH

GMPR GMPR2

1.19e-044842PF00478
DomainIMP_DH_GMPRt

GMPR GMPR2

1.19e-044842IPR001093
DomainIMP_DH_GMP_RED

GMPR GMPR2

1.19e-044842PS00487
DomainIMP_DH/GMP_Rdtase_CS

GMPR GMPR2

1.19e-044842IPR015875
DomainCadherin_cytoplasmic-dom

CDH24 DSG1 CDH18

1.88e-0425843IPR000233
DomainCadherin_C

CDH24 DSG1 CDH18

1.88e-0425843PF01049
DomainCatenin_binding_dom

CDH24 DSG1 CDH18

2.95e-0429843IPR027397
Domain-

CDH24 DSG1 CDH18

2.95e-04298434.10.900.10
DomainRBM1CTR

RBMXL1 RBMX

5.50e-048842PF08081
DomainRBM1CTR

RBMXL1 RBMX

5.50e-048842IPR012604
DomainOrgcat_transp/SVOP

SLC22A2 SVOP

7.05e-049842IPR004749
DomainMFS

SLCO1B7 SLC22A25 SLC22A2 SVOP

1.43e-03108844PS50850
DomainAAA

ATAD3B ATAD3C ATAD3A

1.65e-0352843PF00004
DomainMORN

MORN5 RSPH10B

1.76e-0314842SM00698
DomainATPase_AAA_core

ATAD3B ATAD3C ATAD3A

1.84e-0354843IPR003959
DomainMORN

MORN5 RSPH10B

2.02e-0315842IPR003409
DomainMORN

MORN5 RSPH10B

2.02e-0315842PF02493
DomainAcyltransferase

GPAT3 GPAT4

2.30e-0316842PF01553
DomainGal_Oxase/kelch_b-propeller

KLHDC3 IPP KLHL8

2.38e-0359843IPR011043
DomainPlsC

GPAT3 GPAT4

2.60e-0317842SM00563
DomainPlipid/glycerol_acylTrfase

GPAT3 GPAT4

2.60e-0317842IPR002123
DomainMFS_dom

SLCO1B7 SLC22A25 SLC22A2 SVOP

3.14e-03134844IPR020846
DomainKelch_1

KLHDC3 IPP KLHL8

3.87e-0370843PF01344
DomainKelch_1

KLHDC3 IPP KLHL8

3.87e-0370843IPR006652
DomainRRM_dom_euk

RBMXL1 RBMX

4.76e-0323842IPR003954
DomainRRM_1

RBMXL1 RBMX

4.76e-0323842SM00361
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

2.36e-0732615MM15326
PathwayWP_NRXN1_DELETION_SYNDROME

NLGN3 NLGN4X NLGN2 NLGN1

9.28e-0718614M48098
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.14e-0656615M27616
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

1.01e-0567615MM15327
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

NLGN3 NLGN4X NLGN2 NLGN1

1.18e-0533614M39875
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.61e-0587615M27617
PathwayREACTOME_NEURONAL_SYSTEM

NLGN3 NLGN4X NLGN4Y SLC22A2 GLUL LRRC7 NLGN2 NLGN1

9.20e-05335618MM14503
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

NLGN3 NLGN4X CSAD AOX1 GLUL NLGN2 NLGN1 QDPR

1.73e-04367618M48346
PathwayREACTOME_NEURONAL_SYSTEM

NLGN3 NLGN4X NLGN4Y SLC22A2 GLUL LRRC7 NLGN2 NLGN1

3.71e-04411618M735
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

8.22e-14586510996085
Pubmed

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

8.22e-14586537865312
Pubmed

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.92e-13686521838267
Pubmed

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.92e-13686529724786
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

4.57e-12886530871858
Pubmed

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

NLGN3 NLGN4X NLGN4Y NLGN2

3.48e-11486412669065
Pubmed

Homodimerization and isoform-specific heterodimerization of neuroligins.

NLGN3 NLGN4X NLGN4Y NLGN2

3.48e-11486422671294
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN3 NLGN4X NLGN4Y NLGN1

3.48e-11486416077734
Pubmed

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.75e-111186532973045
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

3.75e-111186526403076
Pubmed

Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.

NLGN3 NLGN4X NLGN2 NLGN1

1.74e-10586415620359
Pubmed

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

2.42e-101586518227507
Pubmed

Binding of neuroligins to PSD-95.

NLGN3 NLGN4X NLGN2 NLGN1

4.35e-0998649278515
Pubmed

DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.

NLGN3 NLGN4X NLGN4Y NLGN2 NLGN1

5.19e-092686534848499
Pubmed

Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.

NLGN3 NLGN2 NLGN1

1.46e-08386328607166
Pubmed

[ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].

ATAD3B ATAD3C ATAD3A

1.46e-08386322192748
Pubmed

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

NLGN3 NLGN4X NLGN4Y

1.46e-08386332011705
Pubmed

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.

ATAD3B ATAD3C ATAD3A

1.46e-08386328549128
Pubmed

Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.

NLGN3 NLGN2 NLGN1

1.46e-08386327217145
Pubmed

Analysis of the neuroligin 4Y gene in patients with autism.

NLGN3 NLGN4X NLGN4Y

1.46e-08386318628683
Pubmed

Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.

NLGN3 NLGN2 NLGN1

1.46e-08386329100073
Pubmed

ATAD3 is a limiting factor in mitochondrial biogenesis and adipogenesis of white adipocyte-like 3T3-L1 cells.

ATAD3B ATAD3C ATAD3A

1.46e-08386338923254
Pubmed

ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly.

ATAD3B ATAD3C ATAD3A

1.46e-08386334936866
Pubmed

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

NLGN4X NLGN4Y NLGN2

1.46e-08386321282647
Pubmed

Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.

NLGN3 NLGN2 NLGN1

1.46e-08386326291161
Pubmed

Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3.

ATAD3B ATAD3C ATAD3A

1.46e-08386325375035
Pubmed

Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses.

NLGN3 NLGN2 NLGN1

1.46e-08386317897391
Pubmed

Neuroligins determine synapse maturation and function.

NLGN3 NLGN2 NLGN1

1.46e-08386316982420
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

NLGN3 ATAD3B NLGN4X ATAD3C ATAD3A NLGN4Y GLUL LRRC7 NLGN1

3.45e-0828186928706196
Pubmed

ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.

ATAD3B ATAD3C ATAD3A

5.83e-08486335236834
Pubmed

Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis.

ATAD3B ATAD3C ATAD3A

5.83e-08486336736924
Pubmed

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.

NLGN3 NLGN4X NLGN4Y

5.83e-08486320579107
Pubmed

The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy.

ATAD3B ATAD3C ATAD3A

5.83e-08486338250153
Pubmed

Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells.

ATAD3B ATAD3C ATAD3A

5.83e-08486329242539
Pubmed

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.

NLGN3 NLGN4X NLGN4Y

5.83e-08486317292328
Pubmed

Neuroligin 2 regulates absence seizures and behavioral arrests through GABAergic transmission within the thalamocortical circuitry.

NLGN3 NLGN2 NLGN1

5.83e-08486332719346
Pubmed

Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.

NLGN3 NLGN2 NLGN1

5.83e-08486330056576
Pubmed

Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues.

ATAD3B ATAD3C ATAD3A

1.45e-07586324239551
Pubmed

5-HT modulation of a medial septal circuit tunes social memory stability.

NLGN3 NLGN2 NLGN1

1.45e-07586334616037
Pubmed

Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.

NLGN3 NLGN2 NLGN1

1.45e-07586327581450
Pubmed

Neuroligin-induced presynaptic differentiation through SLM2-mediated splicing modifications of neurexin in cerebellar cultures.

NLGN3 NLGN2 NLGN1

1.45e-07586328939043
Pubmed

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels.

ATAD3B ATAD3C ATAD3A

1.45e-07586329898916
Pubmed

Impairment of Inhibitory Synapse Formation and Motor Behavior in Mice Lacking the NL2 Binding Partner LHFPL4/GARLH4.

NLGN3 NLGN2 NLGN1

2.90e-07686329742426
Pubmed

Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation.

ATAD3B ATAD3C ATAD3A

2.90e-07686331472450
Pubmed

Structures, alternative splicing, and neurexin binding of multiple neuroligins.

NLGN3 NLGN2 NLGN1

2.90e-0768638576240
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF462 NLGN3 ATAD3B TBC1D9B ATAD3C ATAD3A HSPH1 NLGN2 FHDC1 DHTKD1

4.05e-07493861015368895
Pubmed

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.

ATAD3B ATAD3C ATAD3A

8.10e-07886330914652
Pubmed

Atad3 function is essential for early post-implantation development in the mouse.

ATAD3B ATAD3C ATAD3A

8.10e-07886323372768
Pubmed

Control of excitatory and inhibitory synapse formation by neuroligins.

NLGN3 NLGN2 NLGN1

8.10e-07886315681343
Pubmed

Role of Elavl-like RNA-binding protein in retinal development and signal transduction.

NLGN4X NLGN4Y GLUL NLGN2

1.04e-063186439307290
Pubmed

Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.

NLGN3 NLGN4X NLGN4Y

1.21e-06986323010509
Pubmed

Molecular self-avoidance in synaptic neurexin complexes.

NLGN3 NLGN2 NLGN1

1.21e-06986334919427
Pubmed

A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.

UBAP2L HSPH1 CCT2 CTSB EXOSC2 SF1

1.69e-0614586623349634
Pubmed

TRIM24 is an insulin-responsive regulator of P-bodies.

RBMXL1 DSG1 ATAD3A RBMX TNRC6B

1.71e-068086535803934
Pubmed

Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast.

ATAD3B ATAD3C ATAD3A

2.37e-061186336000457
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NLGN3 NLGN4X NLGN4Y

4.10e-061386327050589
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

ATAD3B ATAD3A RBMX HSPH1 MCM5 CCT2 IDH2 TOP3A

5.05e-0638386829331416
Pubmed

Translational animal models of autism and neurodevelopmental disorders.

NLGN3 NLGN2 NLGN1

5.21e-061486323226954
Pubmed

The structure and expression of the human neuroligin-3 gene.

NLGN3 NLGN2

6.04e-06286210767552
Pubmed

Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons.

NLGN2 NLGN1

6.04e-06286210892652
Pubmed

Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort.

NLGN3 NLGN4X

6.04e-06286227782075
Pubmed

Not all neuroligin 3 and 4X missense variants lead to significant functional inactivation.

NLGN3 NLGN4X

6.04e-06286228948087
Pubmed

Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3.

NLGN3 NLGN1

6.04e-06286235992071
Pubmed

Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses.

NLGN3 NLGN2

6.04e-06286227805570
Pubmed

"ATAD3C regulates ATAD3A assembly and function in the mitochondrial membrane".

ATAD3C ATAD3A

6.04e-06286238092275
Pubmed

Multiple cadherin mRNA expression and developmental regulation of a novel cadherin in the developing mouse eye.

CDH24 CDH18

6.04e-06286210328938
Pubmed

Novel splice isoforms for NLGN3 and NLGN4 with possible implications in autism.

NLGN3 NLGN4X

6.04e-06286216648374
Pubmed

A substitution involving the NLGN4 gene associated with autistic behavior in the Greek population.

NLGN3 NLGN4X

6.04e-06286219645625
Pubmed

Unusually rapid evolution of Neuroligin-4 in mice.

NLGN4X NLGN4Y

6.04e-06286218434543
Pubmed

Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands.

NLGN3 NLGN4X

6.04e-06286215274046
Pubmed

Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism.

NLGN3 NLGN1

6.04e-06286222983708
Pubmed

NLGN1 and NLGN2 in the prefrontal cortex: their role in memory consolidation and strengthening.

NLGN2 NLGN1

6.04e-06286229278843
Pubmed

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

NLGN4X NLGN4Y

6.04e-06286223183221
Pubmed

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

NLGN4X NLGN4Y

6.04e-06286224855039
Pubmed

Analysis of the genes encoding neuroligins NLGN3 and NLGN4 in Bulgarian patients with autism.

NLGN3 NLGN4X

6.04e-06286223431752
Pubmed

Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.

NLGN4X NLGN4Y

6.04e-06286237001827
Pubmed

ATAD 3A and ATAD 3B are distal 1p-located genes differentially expressed in human glioma cell lines and present in vitro anti-oncogenic and chemoresistant properties.

ATAD3B ATAD3A

6.04e-06286218639545
Pubmed

Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.

NLGN4X NLGN4Y

6.04e-06286237080762
Pubmed

Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism.

NLGN3 NLGN1

6.04e-06286225592157
Pubmed

Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection.

NLGN3 NLGN4X

6.04e-06286216508939
Pubmed

Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

NLGN4X NLGN4Y

6.04e-06286229106499
Pubmed

NLGN3/NLGN4 gene mutations are not responsible for autism in the Quebec population.

NLGN3 NLGN4X

6.04e-06286215389766
Pubmed

Molecular characterization of the tumor-associated antigen AAA-TOB3.

ATAD3B ATAD3A

6.04e-06286216909202
Pubmed

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

NLGN4X NLGN4Y

6.04e-06286226456829
Pubmed

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.

NLGN4X NLGN4Y

6.04e-06286224104404
Pubmed

Neuroligin 3 is a vertebrate gliotactin expressed in the olfactory ensheathing glia, a growth-promoting class of macroglia.

NLGN3 NLGN1

6.04e-06286211329178
Pubmed

Reaction mechanism and specificity of human GMP reductase. Substrates, inhibitors, activators, and inactivators.

GMPR GMPR2

6.04e-062862218932
Pubmed

Characterization of the neuroligin gene family expression and evolution in zebrafish.

NLGN3 NLGN1

6.04e-06286220034102
Pubmed

A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.

NLGN4X NLGN4Y

6.04e-06286232243781
Pubmed

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.

NLGN4X NLGN4Y

6.04e-06286222989184
Pubmed

Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.

NLGN3 NLGN2

6.04e-06286236479216
Pubmed

Glycerol-3-phosphate acyltransferases 3 and 4 direct glycerolipid synthesis and affect functionality in activated macrophages.

GPAT3 GPAT4

6.04e-06286230523059
Pubmed

Triacylglycerol synthesis directed by glycerol-3-phosphate acyltransferases -3 and -4 is required for lipid droplet formation and the modulation of the inflammatory response during macrophage to foam cell transition.

GPAT3 GPAT4

6.04e-06286233260006
Pubmed

Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.

NLGN3 NLGN4X

6.04e-06286224570023
Pubmed

No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning level.

NLGN3 NLGN4X

6.04e-06286218189281
Pubmed

The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization.

ATAD3B ATAD3A

6.04e-06286217210950
Pubmed

Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.

NLGN2 NLGN1

6.04e-06286219889999
Pubmed

GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis.

GPAT3 GPAT4

6.04e-06286220181984
Pubmed

Disorder-associated mutations lead to functional inactivation of neuroligins.

NLGN3 NLGN4X

6.04e-06286215150161
Pubmed

Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients.

NLGN3 NLGN4X

6.04e-06286215622415
GeneFamilyGlycerol-3-phosphate acyltransferases

GPAT3 GPAT4

4.30e-0544921035
GeneFamily1-acylglycerol-3-phosphate O-acyltransferases

GPAT3 GPAT4

3.90e-041149246
GeneFamilyAAA ATPases

ATAD3B ATAD3C ATAD3A

3.98e-0453493413
GeneFamilyCD molecules|Type II classical cadherins

CDH24 CDH18

5.51e-04134921186
GeneFamilyEndogenous ligands|C1q and TNF related

C1QL1 C1QL4

1.07e-03184921372
GeneFamilySolute carriers

SLCO1B7 SLC22A25 SLC22A2 SLC38A5 SLC12A7

4.20e-03395495752
GeneFamilyKelch like|BTB domain containing

IPP KLHL8

5.78e-0342492617
GeneFamilyOlfactory receptors, family 8

OR8B12 OR8B8

7.80e-0349492155
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SUSD4 C1R

1.04e-02574921179
CoexpressionGSE2826_WT_VS_BTK_KO_BCELL_DN

HOXC6 TENM4 FHDC1 IDH2 SLC12A7 CTSB GPAT4

3.74e-06200847M4899
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM4 SLC22A2 GPAT3 GMPR IDH2 WNK4

1.27e-06178866dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM4 SLC22A2 GPAT3 GMPR IDH2 WNK4

1.32e-06179866d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM4 SLC22A2 GPAT3 GMPR IDH2 WNK4

1.32e-061798662e49b215b71438400aebb483f2c2c08d5e956961
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

C1QL1 AOX1 C1R SVOP WNK4 ALOX15

2.29e-0619786688a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

C1QL1 AOX1 C1R SVOP WNK4 ALOX15

2.29e-061978662773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 SUSD4 LYPLAL1 IPP PLA2G4E

1.08e-0515086547ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCellfacs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPLAL1 FHDC1 MORN5 WNK4 TOP3A

2.40e-05177865e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCellfacs-Lung-nan-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPLAL1 FHDC1 MORN5 WNK4 TOP3A

2.40e-05177865b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL GMPR FHDC1 CTSB ALOX15

2.46e-05178865eafacc8cd3e986d6ca309e05b6e241331a584fa5
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL GMPR FHDC1 CTSB ALOX15

2.46e-051788656a5c31e976852edc7d9e899da8e2a1bf23d36759
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL GMPR FHDC1 CTSB ALOX15

2.46e-05178865370749834a11d981e9ede26d5f63f0ecb551c015
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTCHD1 NLGN4X LRRC7 MORN5 FOXF2

2.81e-0518386561a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C1QL1 NLGN3 HOXC6 NLGN1 CDH18

3.04e-05186865bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

GLUL GPAT3 GMPR CTSB CDH18

3.12e-0518786588fac9f23047892acccbcc355d02ff079596fedf
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 ZNF462 PLVAP SLC22A2 WNK4

3.28e-051898658e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 ZNF462 PLVAP SLC22A2 WNK4

3.28e-05189865fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 PLVAP CSAD SLC12A7 WNK4

3.36e-051908656f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCellcritical-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ZNF462 PLVAP ALX1 GMPR NLGN1

3.62e-051938656be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell21-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

EBF2 HOXC6 AOX1 C1R FOXF2

3.71e-05194865749dd8113ef260e00facac09de9861d61725124a
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SUSD4 NQO1 MORN5 PPM1H ALOX15

3.90e-05196865d9426eba69047166ffa8179f1654e011c1020328
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SUSD4 NQO1 MORN5 PPM1H ALOX15

3.90e-051968657e19919eafd6ddf547dd4e8aa532a050e182c5cc
ToppCellerythropoietic-Erythrocyte|World / Lineage and Cell class

SLC38A5 MCM5 GMPR CCT2 IDH2

3.90e-051968651642d9340f621cd55987ef8154b48aa306f0f0c8
ToppCelldistal-mesenchymal-Mesothelial-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

C1QL1 NLGN4Y AOX1 C1QL4 CDH18

4.09e-05198865431bf719ee5cce4c9e8b6b405819b67e98fad3ca
ToppCelldistal-mesenchymal-Mesothelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

C1QL1 NLGN4Y AOX1 C1QL4 CDH18

4.09e-0519886552e3cb45472dd6db31ae533e9ea0c3b550f11496
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early|World / Primary Cells by Cluster

CITED2 NBEAL1 RBMX HSPH1 MCM5

4.19e-05199865549391e7a4285da1c0e366654530bcf1cd33fbae
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early-40|World / Primary Cells by Cluster

CITED2 NBEAL1 RBMX HSPH1 MCM5

4.19e-0519986523625d757173bdd35a51c7919ff4b588168d2553
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 NLGN3 C1R NLGN1 WNK4

4.19e-0519986545c3b853900d8c3d5965117d904e3714100138bc
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CITED2 GLUL SLC38A5 C1R FOXF2

4.19e-05199865212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CITED2 GLUL SLC38A5 C1R FOXF2

4.19e-0519986514b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellBiopsy_IPF-Mesenchymal-Mesothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

C1QL1 NLGN4X AOX1 C1R NLGN1

4.29e-05200865553386523fd8f8f36617a0d81032224b7ddce442
ToppCellLA-04._Ventricular_Cardiomyocyte_I|LA / Chamber and Cluster_Paper

ALX1 SLC38A5 FHDC1 SVOP

6.15e-0511086434dcd1e1e16e8b6088ff9a7a40532e8bd000c121
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPAT3 MCM5 GPAT4 ALOX15

8.09e-05118864f0f40a0165156e3fc1584480b473b0e84e10d2cc
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_12|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPAT3 MCM5 GPAT4 ALOX15

8.36e-05119864a6b359e7aafcc197f53eb5e19c3a905bc09497bb
ToppCellControl-PLT_5|World / Disease Group and Platelet Clusters

DSG1 NBEAL1 AOX1 SVOP

1.04e-041268644ba753c4e83eb1d41964edfa22135e047f06c481
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLVAP GLUL CTSB FOXF2

1.21e-04131864aaf87b85fa5886808407ea91721058aaad3472a6
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_macrophage|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PLVAP GLUL CTSB FOXF2

1.21e-04131864384952292627316db18b522066a29ebbc3a6723b
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-late_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PLVAP GLUL SLC38A5 GMPR

1.74e-04144864ca365380ccf5e60d2e3f6272059ff0531759612d
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CITED2 NLGN3 CDH24 PPM1H

1.74e-041448644f46a22dba047d35076e7768e834b0cbcecc8417
ToppCellNS-critical-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CENPE MCM5 DHTKD1 WNK4

1.74e-041448640fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EBF2 ACY3 GMPR FHDC1

1.84e-0414686403a6a442f1f6d173a41aeebbfe41ee08853d9585
ToppCell10x5'-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

GLUL GPAT4 PPM1H PURG

2.55e-04159864c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCell10x5'-bone_marrow-Mast-Mast_cells|bone_marrow / Manually curated celltypes from each tissue

GLUL GPAT4 PPM1H PURG

2.67e-0416186415ba7e69699558353cfeecdcf1dbc2e147379ed6
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1QL1 CDH24 TENM4 MCM5

2.73e-041628643f264263878af630921911c2b344ac56eb1e7099
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACY3 LRRC7 NAP1L6P SVOP

2.73e-04162864fc313fb2c55957faa8c9ca4023b3fce63527c267
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACY3 LRRC7 NAP1L6P SVOP

2.73e-04162864002fac3c5c3030950f9eb9e887d59902586d8452
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACY3 LRRC7 NAP1L6P SVOP

2.73e-0416286408b7f06580d516307516d5475a5dae0fa040f1a4
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACY3 LRRC7 NAP1L6P SVOP

2.73e-041628641fda21a303a08aff6f97819cd8766cd18784d8bc
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Liver / Manually curated celltypes from each tissue

SUSD4 ATAD3C ZNF280D NLGN4Y

3.00e-041668649afa33b5ad27dc33576be592f9b22d8161366838
ToppCellfacs-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE NQO1 SLC38A5 FHDC1

3.07e-0416786416bb7293fc8ca582b7cb4450917aff07b34fc70a
ToppCellfacs-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE NQO1 SLC38A5 FHDC1

3.07e-04167864515988c7035c550a2f072430d9d7027869593d17
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPLAL1 CSAD ACY3 SLC22A2

3.07e-04167864ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCellILEUM-non-inflamed-(4)_Mast|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GLUL GMPR PPM1H CDH18

3.07e-04167864de0cb257def6049830af068f8f74829a708b810f
ToppCellILEUM-non-inflamed-(4)_Mast_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GLUL GMPR PPM1H CDH18

3.07e-0416786485b39e05eb6e18e06b47e374d808e479ca65173c
ToppCellfacs-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE NQO1 SLC38A5 FHDC1

3.07e-04167864f12d00e6c600b0bba3e4e1b1c80b791e095de931
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NLGN4X CHD7 FHDC1 CLRN1

3.14e-04168864af82e07d1eec51fc6530155f37addbce6221885d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSAD ACY3 SLC22A2 NQO1

3.14e-04168864b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NQO1 GPAT3 MCM5 GMPR

3.14e-04168864ca65321259711321c175ede67bd67a47aad81d7a
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPLAL1 CSAD ACY3 SLC22A2

3.21e-04169864f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EBF2 AOX1 C1R NLGN1

3.43e-04172864e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D9B ACY3 GMPR IDH2

3.51e-041738645d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D9B ACY3 GMPR IDH2

3.58e-04174864a9f34d1237f335d27c5560ff514368f4709f9144
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D9B ACY3 GMPR IDH2

3.58e-041748649eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

ZNF462 GLUL GMPR PPM1H

3.58e-04174864e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ALX1 NLGN4X NLGN4Y C1R

3.58e-041748649c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell10x5'-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

ZNF462 GLUL GMPR PPM1H

3.58e-0417486405525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ALX1 NLGN4X NLGN4Y C1R

3.58e-04174864bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 TENM4 IDH2 WNK4

3.66e-04175864e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EBF2 NLGN1 WNK4 ALOX15

3.66e-041758641b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 SUSD4 NLGN2 NLGN1

3.66e-04175864d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GMPR FHDC1 CTSB ALOX15

3.66e-041758642c39c1b112e873403ad2add8595cc256bf0b97a6
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP SLC38A5 MCM5 CTSB

3.66e-04175864b4ff5a74ad22addbdd848dde9ba93d63a0611543
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 SUSD4 NLGN2 NLGN1

3.66e-041758641d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EBF2 NLGN1 WNK4 ALOX15

3.66e-04175864a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP SLC38A5 MCM5 CTSB

3.66e-0417586427a8c6e398638ccdee90c44e2ca6f59acc206cbc
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 GPAT3 NLGN2 CDH18

3.74e-04176864ef0ff02897104e938c8a632357d8f1a6f014e68a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 GPAT3 NLGN2 CDH18

3.74e-04176864da0983929fa682a68e536c298a2d7add188b7563
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

ZNF462 GPAT3 GMPR ALOX15

3.74e-04176864195393b38f1335f2cb96125616d75c164a6026c2
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D9B ACY3 GMPR IDH2

3.74e-04176864d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 AOX1 LRRC7 FOXF2

3.82e-041778649ec7f1e64312d26d434b3312b58386715dbad644
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPH1 GLUL GMPR PPM1H

3.82e-041778640176ffa5e66fa684d0a8264af0db8f77fc391afd
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATAD3B GMPR WNK4 TOP3A

3.82e-04177864e1e45956887371b1c18f1eb479dd930031497520
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP TENM4 DHTKD1 SVOP

3.82e-041778649b02fd91c110b405eba6cb74ceb90b1286535973
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 AOX1 LRRC7 FOXF2

3.82e-04177864016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD4 TENM4 IDH2 WNK4

3.91e-041788644df6218b20c2f076c22346d23260964cc0d73e65
ToppCelldroplet-Spleen-nan-24m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLUL SLC38A5 FHDC1 CTSB

3.91e-041788649c4950357087212b2388116ba8866c359628694d
ToppCellfacs-Diaphragm-Limb_Muscle-18m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP CENPE PSMB8 MCM5

3.91e-0417886440bd605b801d9ae76cffc8f62836092fc2b06812
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL FHDC1 CTSB ALOX15

3.99e-041798647329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL FHDC1 CTSB ALOX15

3.99e-041798646e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A25 TENM4 C1R SLC12A7

3.99e-04179864b35a7f8115c997c390201da01d7cb10b10769aec
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GLUL FHDC1 CTSB ALOX15

3.99e-04179864ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 SUSD4 C1QL4 NLGN1

4.07e-04180864fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 SUSD4 C1QL4 NLGN1

4.07e-04180864907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCellcritical-Lymphoid-NK|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PLVAP ALX1 NLGN1 WNK4

4.07e-041808645abf778395392244daaec876f306ed7e4f388686
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE ACY3 SLC38A5 GMPR

4.16e-041818649dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE ACY3 SLC38A5 GMPR

4.16e-0418186414c2dd946e89ba578711c2d25935b6b3d319b701
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE ACY3 SLC38A5 GMPR

4.16e-04181864c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE ACY3 SLC38A5 GMPR

4.16e-04181864fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCellNS-critical-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PLVAP ALX1 NLGN1 WNK4

4.25e-04182864dd1c59babf7211362452e3e264009d70004d99f6
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 PLVAP CSAD SLC12A7

4.34e-041838646c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CENPE ACY3 SLC38A5 ACOXL

4.34e-04183864dd15e1463a0d57d14800de0df0645c81c56926ae
Drugthiopurinol

AOX1 SLC38A5 GMPR GMPR2

1.76e-0714854CID000667510
Drugmethyl p-nitrobenzoate

NQO1 GMPR GMPR2

2.00e-074853CID000012083
Drug4-nitrohippuric acid

AOX1 GMPR GMPR2

4.99e-075853CID000017549
DrugAC1NS1PP

DSG1 NQO1 GMPR GMPR2

1.03e-0621854CID005327132
DrugSN 23862

NQO1 GMPR GMPR2

1.74e-067853CID000126690
Drug1-aminopyrene

AOX1 NQO1 GMPR GMPR2

2.16e-0625854CID000015352
Drug3-nitrofluoranthene

AOX1 NQO1 GMPR GMPR2

2.54e-0626854CID000013462
DrugCB1954

AOX1 NQO1 GMPR GMPR2

4.00e-0629854CID000089105
Drugallopurinol riboside

AOX1 GMPR GMPR2

4.15e-069853CID000085337
Druglipoamide

NQO1 GMPR GMPR2 CTSB DHTKD1

4.81e-0666855CID000000863
Drug4-(hydroxyamino)quinoline 1-oxide

NQO1 GMPR GMPR2

5.91e-0610853CID000020753
Drug3,5-dinitroaniline

NQO1 GMPR GMPR2

5.91e-0610853CID000012068
Drugmusk ambrette

NQO1 GMPR GMPR2

8.11e-0611853CID000006753
Drug5-nitro-2-furaldehyde

AOX1 GMPR GMPR2

1.08e-0512853CID000012774
Drugdinitrogen

NLGN3 ZNF143 KLHDC3 GLUL IDH2

1.32e-0581855CID000000947
Drug2-methylcarbazole

GMPR GMPR2

1.38e-052852CID000019290
Drugm-nitrobenzamidine hydrochloride

GMPR GMPR2

1.38e-052852CID000165122
Drug3-nitrofluoranthen-6-ol

GMPR GMPR2

1.38e-052852CID000146572
Drug3-nitrofluoranthen-9-ol

GMPR GMPR2

1.38e-052852CID000146573
Drug3-nitrofluoranthen-8-ol

GMPR GMPR2

1.38e-052852CID000146567
Drug1,3,6-trinitropyrene

GMPR GMPR2

1.38e-052852CID000053229
Drug2-nitrobenzofuran

GMPR GMPR2

1.38e-052852CID000036328
Drug1,3,6,8-tetranitropyrene

GMPR GMPR2

1.38e-052852CID000034321
DrugAC1L25J4

GMPR GMPR2

1.38e-052852CID000041328
DrugNSC-13158

AOX1 GLUL NQO1

1.40e-0513853CID000079470
Drugronidazole

AOX1 GMPR GMPR2

1.77e-0514853CID000005094
Drugethyl iodoacetate

AOX1 NQO1 GMPR GMPR2

1.82e-0542854CID000012183
Drug1-nitropyrene

AOX1 NQO1 GMPR GMPR2

2.62e-0546854CID000021694
Drugmusk xylene

NQO1 GMPR GMPR2

3.29e-0517853CID000062329
Drug2,4-DNT

NQO1 GMPR GMPR2 ALOX15

4.27e-0552854CID000008461
Drugp-nitrobenzoic acid

NQO1 GMPR GMPR2

4.66e-0519853CID000006108
Drugtetryl

NQO1 GMPR GMPR2

5.47e-0520853CID000010178
Drugindole-3-aldehyde

KLHDC3 AOX1 NQO1

5.47e-0520853CID000010256
DrugPCMB

NQO1 GMPR IDH2 GMPR2 QDPR CTSB

5.50e-05178856CID000001730
Drug2-aminofluorene

AOX1 NQO1 GMPR GMPR2

6.15e-0557854CID000001539
Drug2-nitronaphthalene

NQO1 GMPR GMPR2

6.36e-0521853CID000011392
DrughMCP

AOX1 NQO1 CTSB

7.35e-0522853CID006450018
Drugbenznidazole

AOX1 GMPR GMPR2

7.35e-0522853CID000031593
Drug4NQO

NLGN3 NQO1 GMPR GMPR2 TOP3A

7.46e-05116855CID000005955
Druganilino acetate

GMPR GMPR2

8.22e-054852CID000153367
Drugc0458

GMPR GMPR2

8.22e-054852CID009543178
Drugnitromethanamine

GMPR GMPR2

8.22e-054852CID000061148
Drug1-amino-8-nitropyrene

GMPR GMPR2

8.22e-054852CID000108113
Drug2,2'-dithiodipyridine

NQO1 SLC38A5 CTSB EXOSC2

8.56e-0562854CID000065093
Drugbeta-NADP

KLHDC3 GLUL NQO1 GMPR IDH2 GMPR2 QDPR DHTKD1 CDH18

8.90e-05490859CID000000929
Drugnitrofuran

NQO1 GMPR GMPR2

1.09e-0425853CID000011865
DrugAC1L1MAZ

AOX1 GMPR GMPR2

1.23e-0426853CID000031772
Drugchloroacetanilide

SLC38A5 GMPR GMPR2

1.23e-0426853CID000011485
Drugisoscopoletin

NQO1 ALOX15

1.37e-045852CID000069894
Drugnitroquinoline

GMPR GMPR2

1.37e-045852CID000025551
Drugmusk tibetene

GMPR GMPR2

1.37e-045852CID000067350
Drug2-hydroxylamino-4-nitrotoluene

GMPR GMPR2

1.37e-045852CID005488156
Drug8-nitrofluoranthene

AOX1 NQO1

1.37e-045852CID000025762
Drugdimetridazole

GMPR GMPR2

1.37e-045852CID000003090
Drugmethylhydroquinone

NQO1 GMPR ALOX15

1.38e-0427853CID000007253
DrugO-342

AOX1 NQO1 SLC38A5

1.38e-0427853CID000014129
DrugNADP(H

ACY3 AOX1 GLUL NQO1 GMPR IDH2 GMPR2 QDPR DHTKD1

1.54e-04527859CID000000930
DrugNFTA

GMPR GMPR2

2.05e-046852CID000010753
Drugbenzofuroxan

NQO1 CTSB

2.05e-046852CID000068075
DrugHPPR -MP

GMPR GMPR2

2.05e-046852CID000086479
DrugN(1)-methylnicotinamide

SLC22A2 AOX1

2.05e-046852ctd:C024058
DrugAC1O3LYN

NQO1 GMPR GMPR2

2.30e-0432853CID006331933
Drugnaphthoquinone

HGS GLUL NQO1 QDPR

2.31e-0480854CID000008530
DrugFMNH2

NQO1 GMPR GMPR2

2.76e-0434853CID000000711
Drug1-nitro-8-nitrosopyrene

GMPR GMPR2

2.86e-047852CID000108093
Druglupenone

NQO1 ALOX15

2.86e-047852CID000092158
Drugnitromide

GMPR GMPR2

2.86e-047852CID000004511
Drug1-nitro-6-nitrosopyrene

GMPR GMPR2

2.86e-047852CID000114987
Diseaseneuromuscular disease (implicated_via_orthology)

ATAD3B ATAD3C ATAD3A

8.88e-084843DOID:440 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

NLGN3 NLGN4X ZNF280D NLGN4Y NLGN2 CHD7 NLGN1

2.72e-07152847DOID:0060041 (implicated_via_orthology)
Diseasesyndrome (implicated_via_orthology)

ATAD3B ATAD3C ATAD3A

1.76e-0518843DOID:225 (implicated_via_orthology)
DiseaseAutism spectrum disorder

PTCHD1 NLGN4X

1.67e-047842cv:C1510586
Diseasestatus epilepticus (biomarker_via_orthology)

NQO1 NLGN2 NLGN1 QDPR

1.95e-04100844DOID:1824 (biomarker_via_orthology)
Diseaseautistic disorder (is_implicated_in)

NLGN3 PTCHD1 NLGN4X

2.36e-0442843DOID:12849 (is_implicated_in)
Diseaseuterine fibroid

EBF2 TNRC6B NLGN2 SVOP TOP3A

2.66e-04199845EFO_0000731
DiseaseX-12844 measurement

SLC22A25 ZNF799

2.85e-049842EFO_0021339
Diseaseinterleukin 12 measurement

ZNF462 TENM4 RBMX

4.70e-0453843EFO_0004753
Diseasetestosterone measurement

EBF2 SLC22A25 ZNF280D CENPE SLC22A2 HLA-H ZNF799 NLGN2 CHD7 KLHL8 SVOP

9.68e-0412758411EFO_0004908
DiseaseC-X-C motif chemokine 16 measurement

ALOX15 ACOXL

1.19e-0318842EFO_0010911
Diseasedisease

SLC22A2 NLGN1

1.62e-0321842EFO_0000408
DiseaseAutism Spectrum Disorders

NLGN3 PTCHD1 NLGN4X

1.86e-0385843C1510586
DiseaseHeadache, type 2 diabetes mellitus

EBF2 NLGN1

1.95e-0323842HP_0002315, MONDO_0005148

Protein segments in the cluster

PeptideGeneStartEntry
HYQGGPTLSMAGMSE

ZNF280D

156

Q6N043
YMGAGGPLEHVMETL

ALX1

21

Q15699
VTGGTHGNEMSGVYL

ACY3

16

Q96HD9
VYQHVTGEMMGGHAI

CTSB

266

P07858
HIGSGEMGAGDGLAM

CDC42SE1

41

Q9NRR8
FAYHVLMRGGDGTSM

C1QL4

156

Q86Z23
HSGMDYAIMTGGDVA

ATAD3A

416

Q9NVI7
FTYHVLMRGGDGTSM

C1QL1

176

O75973
HSGMMGINSYGSQLG

EBF2

421

Q9HAK2
GGEGAESMMGFFHEL

DHTKD1

191

Q96HY7
GMIGYGMAKGAVHQL

QDPR

146

P09417
DLGLMGYVSGFGVME

C1R

586

P00736
GQMGVYPGMQNERHG

CHD7

121

Q9P2D1
YTGMFAMTERGHGSN

ACOXL

86

Q9NUZ1
ETDMMQGGVYGSGGE

AKAP8L

106

Q9ULX6
GEIHMGGQEHFYMET

AOX1

741

Q06278
SGMGFEAFITHSGML

NBEAL1

626

Q6ZS30
LGVYGMGFAGAMAHT

OR8B8

146

Q15620
GGHMDDGGYSMNFNM

RBMX

126

P38159
LGGMVYAIGGEKDSM

IPP

341

Q9Y573
QSEGGSHTMQVMYGC

HLA-H

111

P01893
YSGGVVNMYHMKEDG

PSMB8

241

P28062
GCTYRGMFSEGLMHG

RSPH10B

106

P0C881
GMFSEGLMHGQGTYI

RSPH10B

111

P0C881
GCTYRGMFSEGLMHG

RSPH10B2

106

B2RC85
GMFSEGLMHGQGTYI

RSPH10B2

111

B2RC85
GSMSSGVGEMGDSQV

FHDC1

806

Q9C0D6
NFIMEGGAMVLADGG

MCM5

426

P33992
YGGISAMHAGRSMTL

LRRC7

1301

Q96NW7
PEDGMQFGGSMSLHG

KIAA1109

4646

Q2LD37
NGGVGIKVMYMGEEH

HSPH1

96

Q92598
DMGGHMGGLSGSTTV

CDH24

231

Q86UP0
MGLAMEHGGSYARAG

PLVAP

1

Q9BX97
VGGHDGNEHLGSMEM

KLHL8

371

Q9P2G9
MGIFDQIMSTGGGGH

ALOX15

411

P16050
ADFVMLGGMLAGHSE

GMPR2

236

Q9P2T1
MVYIHGGSYMEGTGN

NLGN1

216

Q8N2Q7
DTGFMRGHGTYMGEE

EXOSC2

36

Q13868
EMQDLGGGERMTGFE

DSG1

641

Q02413
GSGSMYSLQGIHGDM

NQO1

151

P15559
MQRMNSHSGVGYGAD

HOXC6

126

P09630
GGTRSMTSMYGHLLG

PLA2G4E

381

Q3MJ16
GMEPGAGQEGAMFVH

MON1A

136

Q86VX9
IHGGSYMEGTGNMID

NLGN3

206

Q9NZ94
YMEGTGNMIDGSILA

NLGN3

211

Q9NZ94
YIHGGSYMEGTGNMI

NLGN4Y

171

Q8NFZ3
GAYGMGFAGAMAHTG

OR8B12

146

Q8NGG6
GVGMGMYNTDESISG

IDH2

216

P48735
DGCYAMVGQVHGGLM

GPAT3

241

Q53EU6
GYYAMVGQVHGGLMG

GPAT4

261

Q86UL3
ALHSGMDYAIMTGGD

ATAD3C

191

Q5T2N8
VKEGSMMIGYQPHGT

CSAD

446

Q9Y600
GGFSMGGCMAIHLAY

LYPLAL1

121

Q5VWZ2
ADMTYSIINGDGMGI

CDH18

301

Q13634
TMLGSHMYVFGGRAD

KLHDC3

186

Q9BQ90
ADFVMLGGMFSGHTE

GMPR

236

P36959
LFMAGMMVGGNLYGH

SLC22A25

151

Q6T423
GGEAAAMLHNMRVYG

SLC12A7

241

Q9Y666
LYQGLIMHMGLAGDN

SLC22A2

361

O15244
LFLHGGSYMEGTGNM

NLGN2

181

Q8NFZ4
YIHGGSYMEGTGNMI

NLGN4X

171

Q8N0W4
GKTYTMMGSEDHLGV

CENPE

91

Q02224
TMMRGTGMIGYFGHS

PURG

201

Q9UJV8
MMEGLGEHSTAGEMG

NAP1L6P

1

A6NFF2
GCHSQGGYGGLDMMP

FOXF2

236

Q12947
FGMEQEYTLMGTDGH

GLUL

131

P15104
GQEMVGRGMHGAGVT

SVOP

526

Q8N4V2
GGHMDDGGYSMNFNM

RBMXL1

126

Q96E39
IMGSGILGLAYAMAH

SLC38A5

61

Q8WUX1
MLGHGLYGTFEMLSS

PTCHD1

336

Q96NR3
TVYGGGCSEMLMAHA

CCT2

406

P78371
GHSSLYLGTVNVMGM

SLCO1B7

156

G3V0H7
TGMSGMYHGDLTEKL

TBC1D9B

906

Q66K14
ALHSGMDYAIMTGGD

ATAD3B

366

Q5T9A4
LMGEHIHYGAGNMNA

CITED2

51

Q99967
KFMGEMQYGLFHGEG

CLRN1

56

P58418
QGMTEFPGGGMEAQH

ZNF143

11

P52747
HSMVSMLGKGFGDVG

UBAP2L

336

Q14157
NFMGGIMAGSSGSEH

PPM1H

11

Q9ULR3
MYHGMNPSNGDGFLE

SUSD4

1

Q5VX71
AGSVEGSPMHGVYMS

HGS

596

O14964
MAGGYGVMGDDGSID

SMIM19

1

Q96E16
GPYESRMSGEVIMGH

ZNF799

101

Q96GE5
QGHELAMMTYHGNSG

TENM4

1666

Q6N022
PGHLGMGLVEGYDSM

TOP3A

561

Q13472
GSLNYNIMMHEGFGK

ZNF462

146

Q96JM2
AASGLSDVGEGMGQM

WNK4

646

Q96J92
VGSGVYRLHQGKGMM

SF1

456

Q15637
SSGGMDYGMVGGKEA

TNRC6B

1376

Q9UPQ9
MEEMSYGENSGTHVG

PRO0461

1

Q9UI25
YVGEMKDGMFHGEGT

MORN5

31

Q5VZ52