| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | 5.19e-07 | 1412 | 21 | 10 | GO:0000981 | |
| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | 7.60e-06 | 1459 | 21 | 9 | GO:0000977 | |
| GeneOntologyMolecularFunction | DNA-binding transcription repressor activity, RNA polymerase II-specific | 3.12e-04 | 320 | 21 | 4 | GO:0001227 | |
| GeneOntologyMolecularFunction | DNA-binding transcription repressor activity | 3.35e-04 | 326 | 21 | 4 | GO:0001217 | |
| GeneOntologyMolecularFunction | K63-linked polyubiquitin modification-dependent protein binding | 3.37e-04 | 26 | 21 | 2 | GO:0070530 | |
| GeneOntologyMolecularFunction | polyubiquitin modification-dependent protein binding | 1.74e-03 | 59 | 21 | 2 | GO:0031593 | |
| GeneOntologyMolecularFunction | cysteine-type deubiquitinase activity | 6.32e-03 | 114 | 21 | 2 | GO:0004843 | |
| GeneOntologyMolecularFunction | deubiquitinase activity | 7.44e-03 | 124 | 21 | 2 | GO:0101005 | |
| GeneOntologyMolecularFunction | ubiquitin-like protein peptidase activity | 9.01e-03 | 137 | 21 | 2 | GO:0019783 | |
| GeneOntologyBiologicalProcess | protein deubiquitination involved in ubiquitin-dependent protein catabolic process | 2.75e-05 | 8 | 21 | 2 | GO:0071947 | |
| GeneOntologyBiologicalProcess | protein K11-linked deubiquitination | 4.42e-05 | 10 | 21 | 2 | GO:0035871 | |
| GeneOntologyBiologicalProcess | negative regulation of transcription by RNA polymerase II | 5.48e-05 | 1053 | 21 | 7 | GO:0000122 | |
| GeneOntologyBiologicalProcess | negative regulation of DNA-templated transcription | 3.25e-04 | 1399 | 21 | 7 | GO:0045892 | |
| GeneOntologyBiologicalProcess | negative regulation of RNA biosynthetic process | 3.45e-04 | 1413 | 21 | 7 | GO:1902679 | |
| GeneOntologyBiologicalProcess | protein K48-linked deubiquitination | 4.51e-04 | 31 | 21 | 2 | GO:0071108 | |
| GeneOntologyBiologicalProcess | hypothalamus development | 4.51e-04 | 31 | 21 | 2 | GO:0021854 | |
| GeneOntologyBiologicalProcess | protein K63-linked deubiquitination | 4.81e-04 | 32 | 21 | 2 | GO:0070536 | |
| GeneOntologyCellularComponent | chromatin | 2.94e-07 | 1480 | 20 | 10 | GO:0000785 | |
| MousePheno | utricular degeneration | 5.83e-06 | 3 | 20 | 2 | MP:0004332 | |
| MousePheno | abnormal hypothalamus physiology | 6.38e-06 | 26 | 20 | 3 | MP:0005645 | |
| MousePheno | vestibular saccular degeneration | 4.07e-05 | 7 | 20 | 2 | MP:0004329 | |
| MousePheno | abnormal diencephalon morphology | 5.07e-05 | 298 | 20 | 5 | MP:0000830 | |
| MousePheno | abnormal hypothalamus secretion | 1.27e-04 | 12 | 20 | 2 | MP:0001752 | |
| MousePheno | abnormal vertebral pedicle morphology | 1.27e-04 | 12 | 20 | 2 | MP:0004604 | |
| MousePheno | absent semicircular canals | 1.27e-04 | 12 | 20 | 2 | MP:0000036 | |
| MousePheno | abnormal hypothalamic nucleus morphology | 1.50e-04 | 13 | 20 | 2 | MP:0020872 | |
| MousePheno | decreased vestibular hair cell number | 2.31e-04 | 16 | 20 | 2 | MP:0004328 | |
| MousePheno | decreased circulating growth hormone level | 2.61e-04 | 17 | 20 | 2 | MP:0005120 | |
| MousePheno | abnormal vestibular hair cell number | 3.28e-04 | 19 | 20 | 2 | MP:0004326 | |
| MousePheno | small adenohypophysis | 4.83e-04 | 23 | 20 | 2 | MP:0008321 | |
| MousePheno | abnormal crista ampullaris morphology | 7.19e-04 | 28 | 20 | 2 | MP:0004249 | |
| MousePheno | small pituitary gland | 8.26e-04 | 30 | 20 | 2 | MP:0005361 | |
| MousePheno | abnormal endolymphatic duct morphology | 8.82e-04 | 31 | 20 | 2 | MP:0006011 | |
| MousePheno | abnormal pituitary gland morphology | 8.90e-04 | 135 | 20 | 3 | MP:0000633 | |
| MousePheno | abnormal semicircular canal ampulla morphology | 9.40e-04 | 32 | 20 | 2 | MP:0008488 | |
| Domain | Homeobox_CS | 2.10e-13 | 186 | 21 | 9 | IPR017970 | |
| Domain | Homeobox | 1.68e-12 | 234 | 21 | 9 | PF00046 | |
| Domain | HOMEOBOX_1 | 1.82e-12 | 236 | 21 | 9 | PS00027 | |
| Domain | HOX | 1.89e-12 | 237 | 21 | 9 | SM00389 | |
| Domain | Homeobox_dom | 2.04e-12 | 239 | 21 | 9 | IPR001356 | |
| Domain | HOMEOBOX_2 | 2.04e-12 | 239 | 21 | 9 | PS50071 | |
| Domain | - | 9.30e-12 | 283 | 21 | 9 | 1.10.10.60 | |
| Domain | Homeodomain-like | 3.88e-11 | 332 | 21 | 9 | IPR009057 | |
| Domain | Cezanne-2 | 1.20e-06 | 2 | 21 | 2 | IPR033477 | |
| Domain | Znf_A20 | 2.52e-05 | 7 | 21 | 2 | IPR002653 | |
| Domain | ZF_A20 | 2.52e-05 | 7 | 21 | 2 | PS51036 | |
| Domain | ZnF_A20 | 2.52e-05 | 7 | 21 | 2 | SM00259 | |
| Domain | zf-A20 | 2.52e-05 | 7 | 21 | 2 | PF01754 | |
| Domain | OTU | 9.32e-05 | 13 | 21 | 2 | PF02338 | |
| Domain | OTU | 1.25e-04 | 15 | 21 | 2 | PS50802 | |
| Domain | OTU_dom | 1.25e-04 | 15 | 21 | 2 | IPR003323 | |
| Domain | OAR | 1.25e-04 | 15 | 21 | 2 | PF03826 | |
| Domain | Homeobox_metazoa | 1.35e-04 | 90 | 21 | 3 | IPR020479 | |
| Domain | OAR | 1.43e-04 | 16 | 21 | 2 | PS50803 | |
| Domain | OAR_dom | 1.43e-04 | 16 | 21 | 2 | IPR003654 | |
| Domain | UBA-like | 2.33e-03 | 64 | 21 | 2 | IPR009060 | |
| Domain | HTH_motif | 2.70e-03 | 69 | 21 | 2 | IPR000047 | |
| Pathway | REACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES | 1.78e-04 | 32 | 9 | 2 | MM15290 | |
| Pathway | REACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES | 2.65e-04 | 39 | 9 | 2 | M27579 | |
| Pubmed | 1.39e-10 | 263 | 21 | 7 | 20932939 | ||
| Pubmed | 1.90e-10 | 3 | 21 | 3 | 11091080 | ||
| Pubmed | Phylogenetic conservation and physical mapping of members of the H6 homeobox gene family. | 1.90e-10 | 3 | 21 | 3 | 7647458 | |
| Pubmed | A census of human transcription factors: function, expression and evolution. | 1.20e-09 | 908 | 21 | 9 | 19274049 | |
| Pubmed | Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene. | 1.59e-08 | 9 | 21 | 3 | 9435283 | |
| Pubmed | 1.29e-07 | 77 | 21 | 4 | 21525287 | ||
| Pubmed | 2.51e-07 | 21 | 21 | 3 | 15363417 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 19253379 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 28398627 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 33048949 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 10543441 | ||
| Pubmed | Impact of cytosine methylation on DNA binding specificities of human transcription factors. | 6.33e-07 | 544 | 21 | 6 | 28473536 | |
| Pubmed | Transcriptional antagonism between Hmx1 and Nkx2.5 for a shared DNA-binding site. | 1.04e-06 | 3 | 21 | 2 | 10206974 | |
| Pubmed | Assignment of the murine Hmx2 and Hmx3 homeobox genes to the distal region of mouse chromosome 7. | 1.04e-06 | 3 | 21 | 2 | 9421269 | |
| Pubmed | Regionalized expression of Nkx5-1, Nkx5-2, Pax2 and sek genes during mouse inner ear development. | 2.08e-06 | 4 | 21 | 2 | 8970821 | |
| Pubmed | QRX, a novel homeobox gene, modulates photoreceptor gene expression. | 2.08e-06 | 4 | 21 | 2 | 15028672 | |
| Pubmed | 2.08e-06 | 4 | 21 | 2 | 7510254 | ||
| Pubmed | Nkx5-1 controls semicircular canal formation in the mouse inner ear. | 2.08e-06 | 4 | 21 | 2 | 9389661 | |
| Pubmed | 2.08e-06 | 4 | 21 | 2 | 8541222 | ||
| Pubmed | 7.28e-06 | 7 | 21 | 2 | 18281465 | ||
| Pubmed | Hmx2 homeobox gene control of murine vestibular morphogenesis. | 1.25e-05 | 9 | 21 | 2 | 11748138 | |
| Pubmed | 1.44e-05 | 251 | 21 | 4 | 29031500 | ||
| Pubmed | 1.56e-05 | 10 | 21 | 2 | 26189100 | ||
| Pubmed | Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. | 1.90e-05 | 11 | 21 | 2 | 10433909 | |
| Pubmed | 2.28e-05 | 12 | 21 | 2 | 23226461 | ||
| Pubmed | 2.70e-05 | 13 | 21 | 2 | 11071765 | ||
| Pubmed | Differential expression of LIM domain-only (LMO) genes in the developing mouse inner ear. | 2.70e-05 | 13 | 21 | 2 | 16597514 | |
| Pubmed | Three-dimensional molecular architecture of mouse organogenesis. | 2.95e-05 | 100 | 21 | 3 | 37524711 | |
| Pubmed | 3.15e-05 | 14 | 21 | 2 | 23457544 | ||
| Pubmed | Decoding neuronal composition and ontogeny of individual hypothalamic nuclei. | 3.63e-05 | 15 | 21 | 2 | 33600763 | |
| Pubmed | Head bobber: an insertional mutation causes inner ear defects, hyperactive circling, and deafness. | 3.63e-05 | 15 | 21 | 2 | 22383091 | |
| Pubmed | Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice. | 4.15e-05 | 16 | 21 | 2 | 18163532 | |
| Pubmed | 4.15e-05 | 16 | 21 | 2 | 27856909 | ||
| Pubmed | Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus. | 4.70e-05 | 17 | 21 | 2 | 16900517 | |
| Pubmed | 5.28e-05 | 18 | 21 | 2 | 21930923 | ||
| Pubmed | 5.39e-05 | 709 | 21 | 5 | 22988430 | ||
| Pubmed | 5.90e-05 | 19 | 21 | 2 | 23827681 | ||
| Pubmed | Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation. | 5.90e-05 | 19 | 21 | 2 | 18697938 | |
| Pubmed | 5.90e-05 | 19 | 21 | 2 | 31420539 | ||
| Pubmed | Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling. | 5.90e-05 | 19 | 21 | 2 | 26911688 | |
| Pubmed | Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear. | 5.90e-05 | 19 | 21 | 2 | 19913004 | |
| Pubmed | Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells. | 6.55e-05 | 20 | 21 | 2 | 16469766 | |
| Pubmed | Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. | 8.72e-05 | 23 | 21 | 2 | 29795232 | |
| Pubmed | Cascade diversification directs generation of neuronal diversity in the hypothalamus. | 9.51e-05 | 24 | 21 | 2 | 33887179 | |
| Pubmed | 1.12e-04 | 26 | 21 | 2 | 23536097 | ||
| Pubmed | 1.21e-04 | 27 | 21 | 2 | 30063881 | ||
| Pubmed | 1.30e-04 | 28 | 21 | 2 | 32868762 | ||
| Pubmed | Specification of jaw identity by the Hand2 transcription factor. | 1.30e-04 | 28 | 21 | 2 | 27329940 | |
| Pubmed | 1.30e-04 | 28 | 21 | 2 | 23595746 | ||
| Pubmed | 1.30e-04 | 28 | 21 | 2 | 17698011 | ||
| Pubmed | 1.70e-04 | 32 | 21 | 2 | 33669244 | ||
| Pubmed | 2.95e-04 | 42 | 21 | 2 | 26166575 | ||
| Pubmed | Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne. | 4.18e-04 | 50 | 21 | 2 | 31699778 | |
| Cytoband | 10q26.13 | 1.39e-04 | 38 | 21 | 2 | 10q26.13 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr10q26 | 4.02e-03 | 207 | 21 | 2 | chr10q26 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr4p16 | 4.60e-03 | 222 | 21 | 2 | chr4p16 | |
| GeneFamily | PRD class homeoboxes and pseudogenes | 1.74e-10 | 92 | 17 | 6 | 521 | |
| GeneFamily | NKL subclass homeoboxes and pseudogenes | 3.19e-05 | 67 | 17 | 3 | 519 | |
| GeneFamily | OTU domain containing | 1.12e-04 | 17 | 17 | 2 | 669 | |
| GeneFamily | Ankyrin repeat domain containing | 2.13e-02 | 242 | 17 | 2 | 403 | |
| Coexpression | MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | 2.20e-11 | 272 | 21 | 8 | M1938 | |
| Coexpression | MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | 2.93e-11 | 282 | 21 | 8 | MM822 | |
| Coexpression | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | 2.49e-07 | 350 | 21 | 6 | M1949 | |
| Coexpression | MIKKELSEN_MEF_HCP_WITH_H3K27ME3 | 2.53e-07 | 591 | 21 | 7 | M2019 | |
| Coexpression | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | 2.80e-07 | 357 | 21 | 6 | MM828 | |
| Coexpression | MIKKELSEN_MEF_HCP_WITH_H3K27ME3 | 2.83e-07 | 601 | 21 | 7 | MM866 | |
| Coexpression | BENPORATH_EED_TARGETS | 1.22e-05 | 1059 | 21 | 7 | M7617 | |
| Coexpression | BENPORATH_PRC2_TARGETS | 1.35e-04 | 650 | 21 | 5 | M8448 | |
| Coexpression | BENPORATH_ES_WITH_H3K27ME3 | 1.83e-04 | 1115 | 21 | 6 | M10371 | |
| ToppCell | Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6-Inhibitory_Neuron.Slc17a6-Gad1Gad2.Asb4_(Periventricular_Fiber_System_(Pv))-|Thalamus / BrainAtlas - Mouse McCarroll V32 | 1.14e-05 | 94 | 21 | 3 | be1dcfe287f58d608ccdb47cf9c1d12b5e3aa60d | |
| ToppCell | Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32 | 1.14e-05 | 94 | 21 | 3 | 576c37fa53fab679f5e8786f5c798e18998186e9 | |
| ToppCell | Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Slc17a6-Inhibitory_Neuron.Slc17a6-Gad1Gad2.Asb4_(Periventricular_Fiber_System_(Pv))|Thalamus / BrainAtlas - Mouse McCarroll V32 | 1.14e-05 | 94 | 21 | 3 | 82e9178c848468497295c4cc59c662b9279208a1 | |
| ToppCell | TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-2|TCGA-Lung / Sample_Type by Project: Shred V9 | 4.35e-05 | 147 | 21 | 3 | 457bc1175810f241ed8966b76ed4fc4ef3fb144c | |
| ToppCell | CD8+_Memory_T_cell-RSV-6|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster | 5.39e-05 | 158 | 21 | 3 | 5ae737757a49fc96bde1e57e02066f9f65654ea1 | |
| ToppCell | E12.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase | 9.18e-05 | 189 | 21 | 3 | 620d30bb6211fff6adab0638d0d994f547167a29 | |
| Drug | octogen | 1.73e-06 | 26 | 21 | 3 | CID000017596 | |
| Drug | o-terphenyl | 2.26e-05 | 8 | 21 | 2 | CID000006766 | |
| Drug | benzanthrone | 2.60e-04 | 26 | 21 | 2 | ctd:C012768 | |
| Drug | tamoxifen citrate; Up 200; 1uM; MCF7; HG-U133A | 7.79e-04 | 199 | 21 | 3 | 143_UP | |
| Drug | ss,ss-carotene | 8.02e-04 | 201 | 21 | 3 | CID000000573 | |
| Drug | KN 93 | 8.18e-04 | 46 | 21 | 2 | ctd:C072105 | |
| Drug | W 7 | 8.91e-04 | 48 | 21 | 2 | ctd:C017967 | |
| Drug | Ra X Peptide | 1.30e-03 | 58 | 21 | 2 | CID006444175 | |
| Disease | Congenital small ears | 3.52e-04 | 41 | 20 | 2 | C0152423 | |
| Disease | Osteoporosis, Senile | 7.80e-04 | 61 | 20 | 2 | C0029459 | |
| Disease | Osteoporosis, Age-Related | 7.80e-04 | 61 | 20 | 2 | C0001787 | |
| Disease | Post-Traumatic Osteoporosis | 7.80e-04 | 61 | 20 | 2 | C0751406 | |
| Disease | Osteoporosis | 8.32e-04 | 63 | 20 | 2 | C0029456 | |
| Disease | longitudinal BMI measurement | 1.40e-03 | 82 | 20 | 2 | EFO_0005937 | |
| Disease | conotruncal heart malformations | 2.69e-03 | 114 | 20 | 2 | MONDO_0016581 | |
| Disease | creatinine measurement | 4.04e-03 | 995 | 20 | 4 | EFO_0004518 | |
| Disease | photoreceptor cell layer thickness measurement | 4.47e-03 | 148 | 20 | 2 | EFO_0803370 | |
| Disease | Craniofacial Abnormalities | 4.96e-03 | 156 | 20 | 2 | C0376634 | |
| Disease | Rheumatoid Arthritis | 6.13e-03 | 174 | 20 | 2 | C0003873 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| KNNRWTWVQSNARLL | 356 | P35869 | |
| DRVQVWFQNRRAKWK | 181 | Q8N693 | |
| WFQNRRAKWKRNQRV | 186 | Q8N693 | |
| WAQFKIQWNQRWGRR | 406 | P30988 | |
| FKRASNAFKTWNRRW | 276 | Q96P50 | |
| NAFKTWNRRWFSIQN | 281 | Q96P50 | |
| VQIWFQNQRAKWRKQ | 126 | Q2M1V0 | |
| VQVWFQNRRAKWRRQ | 71 | Q96IS3 | |
| KRRWRWQQTQQNKES | 231 | Q6GQQ9 | |
| VKIWFQNRRNKWKRQ | 271 | A6NHT5 | |
| QVKIWFQNRRNKWKR | 246 | Q9NP08 | |
| TQVKTWFQNRRNKWK | 191 | A2RU54 | |
| WFQNRRNKWKRQLSA | 196 | A2RU54 | |
| LKRRWRWQQTQQNKE | 246 | Q8TE49 | |
| AWQLGKSNRFRRQQW | 566 | P57679 | |
| SRVQVWFQNRRAKWK | 146 | Q5XKR4 | |
| SCANKLLRWLRNWQK | 606 | P35251 | |
| LRQRKNWWKDGRFQS | 371 | Q9NXP7 | |
| QVWFQNRRAKWRRQE | 181 | Q9Y2V3 | |
| QPQNASFVKRNRWWL | 326 | Q5JTV8 | |
| RANQKFRLWRWLQKC | 276 | Q8IUH4 | |
| RANEAQWFRKTAWNL | 631 | Q8IYF3 | |
| PSFQWNVLNRSRRWK | 366 | Q14679 | |
| ESRVQVWFQNRRAKW | 146 | A6NJT0 |