Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC22A18 SLCO1B3 SLC9A8 SLCO1B1 SLC4A5 SLC39A8	6.61e-06	296	32	6	GO:0015291
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC22A18 SLCO1B3 SLC9A8 ABCA5 SLCO1B1 SLC4A5 SLC39A8	8.52e-06	477	32	7	GO:0022804
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC22A18 SLCO1B3 SLC9A8 ABCA5 SLCO1B1 SLC4A5 TRPC1 SLC39A8 RHAG	6.93e-05	1180	32	9	GO:0022857
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC22A18 SLCO1B3 SLCO1B1 SLC4A5 SLC39A8	9.57e-05	293	32	5	GO:0008514
GeneOntologyMolecularFunction	transporter activity	SLC22A18 SLCO1B3 SLC9A8 ABCA5 SLCO1B1 SLC4A5 TRPC1 SLC39A8 RHAG	1.37e-04	1289	32	9	GO:0005215
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A5 SLC39A8	1.92e-04	13	32	2	GO:0140410
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	SLCO1B3 SLCO1B1	2.24e-04	14	32	2	GO:0015132
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	SLCO1B3 SLCO1B1	2.58e-04	15	32	2	GO:0071714
GeneOntologyMolecularFunction	oligopeptide transmembrane transporter activity	SLCO1B3 SLCO1B1	2.94e-04	16	32	2	GO:0035673
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLCO1B3 SLCO1B1	3.75e-04	18	32	2	GO:0015347
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC4A5 SLC39A8	1.20e-03	32	32	2	GO:0015106
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	SLCO1B3 SLCO1B1	1.35e-03	34	32	2	GO:0015125
GeneOntologyMolecularFunction	symporter activity	SLC22A18 SLC4A5 SLC39A8	1.76e-03	150	32	3	GO:0015293
GeneOntologyMolecularFunction	amide transmembrane transporter activity	SLCO1B3 SLCO1B1	2.06e-03	42	32	2	GO:0042887
GeneOntologyMolecularFunction	G protein-coupled receptor activity	TAS1R2 OR8B12 NPR3 OR2AP1 LPAR1 OR5F1	2.50e-03	884	32	6	GO:0004930
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC9A8 SLC4A5 TRPC1 SLC39A8 RHAG	3.00e-03	627	32	5	GO:0022890
GeneOntologyMolecularFunction	lipid transporter activity	SLCO1B3 ABCA5 SLCO1B1	3.75e-03	196	32	3	GO:0005319
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLCO1B3 SLCO1B1	5.61e-03	70	32	2	GO:1901618
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	SLCO1B3 SLCO1B1	6.09e-03	73	32	2	GO:0170055
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC9A8 SLC4A5 TRPC1 SLC39A8	6.23e-03	465	32	4	GO:0046873
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC9A8 SLC4A5 TRPC1 SLC39A8 RHAG	6.69e-03	758	32	5	GO:0015318
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLCO1B3 SLCO1B1	9.13e-03	90	32	2	GO:0008028
GeneOntologyMolecularFunction	flavin adenine dinucleotide binding	SARDH ACAD11	9.92e-03	94	32	2	GO:0050660
GeneOntologyMolecularFunction	amide binding	NPR3 SARDH PANK1	1.20e-02	299	32	3	GO:0033218
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC9A8 SLC4A5 SLC39A8	1.22e-02	301	32	3	GO:0022853
GeneOntologyBiologicalProcess	bicarbonate transport	SLC4A5 SLC39A8 RHAG	2.76e-05	38	32	3	GO:0015701
GeneOntologyBiologicalProcess	pigment catabolic process	SLCO1B3 SLCO1B1	1.27e-04	11	32	2	GO:0046149
GeneOntologyBiologicalProcess	heme catabolic process	SLCO1B3 SLCO1B1	1.27e-04	11	32	2	GO:0042167
GeneOntologyBiologicalProcess	secretion by tissue	NPR3 SLC4A5 TRPC1	1.33e-04	64	32	3	GO:0032941
GeneOntologyBiologicalProcess	porphyrin-containing compound catabolic process	SLCO1B3 SLCO1B1	1.80e-04	13	32	2	GO:0006787
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	PRKD3 TAS1R2 DGKI OR8B12 NPR3 OR2AP1 LPAR1 TRPC1 OR5F1	1.95e-04	1395	32	9	GO:0007186
GeneOntologyBiologicalProcess	tetrapyrrole catabolic process	SLCO1B3 SLCO1B1	2.10e-04	14	32	2	GO:0033015
GeneOntologyBiologicalProcess	sodium-independent organic anion transport	SLCO1B3 SLCO1B1	2.42e-04	15	32	2	GO:0043252
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	PKHD1 SLC9A8 SLC4A5 TRPC1 SLC39A8 RHAG	3.41e-04	622	32	6	GO:0006873
GeneOntologyBiologicalProcess	pigment metabolic process	SLCO1B3 SLCO1B1 TRPC1	4.13e-04	94	32	3	GO:0042440
GeneOntologyBiologicalProcess	regulation of body fluid levels	DGKI NPR3 VWF SLC4A5 TRPC1	5.52e-04	442	32	5	GO:0050878
GeneOntologyBiologicalProcess	oligopeptide transport	SLCO1B3 SLCO1B1	5.78e-04	23	32	2	GO:0006857
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	PKHD1 SLC9A8 SLC4A5 TRPC1 SLC39A8 RHAG	6.62e-04	705	32	6	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	PKHD1 SLC9A8 SLC4A5 TRPC1 SLC39A8 RHAG	7.23e-04	717	32	6	GO:0050801
GeneOntologyCellularComponent	apical plasma membrane	PKHD1 SLC22A18 SLC9A8 MUC4 SLC4A5 SLC39A8	8.39e-05	487	32	6	GO:0016324
GeneOntologyCellularComponent	basolateral plasma membrane	SLCO1B3 SLCO1B1 SLC4A5 TRPC1 SLC39A8	1.17e-04	320	32	5	GO:0016323
GeneOntologyCellularComponent	basal plasma membrane	SLCO1B3 SLCO1B1 SLC4A5 TRPC1 SLC39A8	1.87e-04	354	32	5	GO:0009925
GeneOntologyCellularComponent	apical part of cell	PKHD1 SLC22A18 SLC9A8 MUC4 SLC4A5 SLC39A8	2.43e-04	592	32	6	GO:0045177
GeneOntologyCellularComponent	basal part of cell	SLCO1B3 SLCO1B1 SLC4A5 TRPC1 SLC39A8	2.54e-04	378	32	5	GO:0045178
HumanPheno	Conjunctival icterus	PKHD1 SLCO1B3 SLCO1B1	4.52e-07	7	13	3	HP:0032106
HumanPheno	Intermittent jaundice	SLCO1B3 SLCO1B1 RHAG	1.08e-06	9	13	3	HP:0001046
HumanPheno	Bilirubinuria	SLCO1B3 SLCO1B1	6.01e-06	2	13	2	HP:0031811
HumanPheno	Conjugated hyperbilirubinemia	PKHD1 SLCO1B3 SLCO1B1	1.04e-04	38	13	3	HP:0002908
HumanPheno	Porphyrinuria	SLCO1B3 SLCO1B1	1.67e-04	8	13	2	HP:0010473
HumanPheno	Hyperbilirubinemia	PKHD1 SLCO1B3 SLCO1B1 RHAG	2.42e-04	130	13	4	HP:0002904
HumanPheno	Abnormal circulating bilirubin concentration	PKHD1 SLCO1B3 SLCO1B1 RHAG	2.49e-04	131	13	4	HP:0033479
Domain	OA_transporter	SLCO1B3 SLCO1B1	1.86e-04	12	32	2	IPR004156
Domain	OATP	SLCO1B3 SLCO1B1	1.86e-04	12	32	2	PF03137
Domain	VWFD	VWF MUC4	3.36e-04	16	32	2	PS51233
Domain	VWD	VWF MUC4	3.36e-04	16	32	2	SM00216
Domain	VWF_type-D	VWF MUC4	3.36e-04	16	32	2	IPR001846
Domain	VWD	VWF MUC4	3.36e-04	16	32	2	PF00094
Domain	MFS	SLC22A18 SLCO1B3 SLCO1B1	8.25e-04	108	32	3	PS50850
Domain	MFS_dom	SLC22A18 SLCO1B3 SLCO1B1	1.54e-03	134	32	3	IPR020846
Domain	Kazal_2	SLCO1B3 SLCO1B1	1.73e-03	36	32	2	PF07648
Domain	ANF_receptor	TAS1R2 NPR3	1.82e-03	37	32	2	PF01094
Domain	ANF_lig-bd_rcpt	TAS1R2 NPR3	1.82e-03	37	32	2	IPR001828
Domain	Peripla_BP_I	TAS1R2 NPR3	2.03e-03	39	32	2	IPR028082
Domain	KAZAL	SLCO1B3 SLCO1B1	2.81e-03	46	32	2	SM00280
Domain	KAZAL_2	SLCO1B3 SLCO1B1	3.31e-03	50	32	2	PS51465
Domain	Kazal_dom	SLCO1B3 SLCO1B1	3.44e-03	51	32	2	IPR002350
Domain	C1_1	PRKD3 DGKI	4.28e-03	57	32	2	PF00130
Domain	ZF_DAG_PE_1	PRKD3 DGKI	5.37e-03	64	32	2	PS00479
Domain	ZF_DAG_PE_2	PRKD3 DGKI	5.37e-03	64	32	2	PS50081
Domain	C1	PRKD3 DGKI	5.53e-03	65	32	2	SM00109
Domain	PE/DAG-bd	PRKD3 DGKI	5.70e-03	66	32	2	IPR002219
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC22A18 SLCO1B3 SLC9A8 SLCO1B1 SLC4A5 SLC39A8 RHAG	3.13e-07	238	28	7	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC22A18 SLCO1B3 SLC9A8 SLCO1B1 SLC4A5 SLC39A8 RHAG	4.25e-07	249	28	7	M5988
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC22A18 SLCO1B3 SLC9A8 ABCA5 SLCO1B1 SLC4A5 TRPC1 SLC39A8 RHAG	4.10e-06	681	28	9	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC22A18 SLCO1B3 SLC9A8 ABCA5 SLCO1B1 SLC4A5 TRPC1 SLC39A8 RHAG	7.73e-06	736	28	9	M27287
Pathway	REACTOME_SLC_TRANSPORTER_DISORDERS	SLC22A18 SLCO1B3 SLCO1B1 RHAG	4.12e-05	99	28	4	M27474
Pathway	REACTOME_ATORVASTATIN_ADME	SLCO1B3 SLCO1B1	1.36e-04	9	28	2	M45020
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO1B3 SLCO1B1	2.07e-04	11	28	2	M930
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO1B3 SLCO1B1	2.48e-04	12	28	2	MM15476
Pathway	WP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS	SLCO1B3 SLCO1B1	2.48e-04	12	28	2	M48096
Pathway	WP_SULFATASE_AND_AROMATASE_PATHWAY	SLCO1B3 SLCO1B1	3.41e-04	14	28	2	M48085
Pathway	REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS	SLC22A18 SLCO1B3 SLCO1B1 RHAG	3.89e-04	177	28	4	M27476
Pathway	REACTOME_HEME_DEGRADATION	SLCO1B3 SLCO1B1	3.93e-04	15	28	2	M27060
Pathway	REACTOME_ATORVASTATIN_ADME	SLCO1B3 SLCO1B1	3.93e-04	15	28	2	MM15697
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC22A18 SLC39A8 RHAG	4.48e-04	76	28	3	MM15072
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	SLCO1B3 SLCO1B1	5.71e-04	18	28	2	M4862
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC22A18 SLC39A8 RHAG	6.00e-04	84	28	3	M27334
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	SLCO1B3 SLCO1B1	6.37e-04	19	28	2	MM14612
Pathway	REACTOME_HEME_DEGRADATION	SLCO1B3 SLCO1B1	7.07e-04	20	28	2	MM14721
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	SLCO1B3 SLCO1B1	1.29e-03	27	28	2	M1088
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	SLCO1B3 SLCO1B1	1.49e-03	29	28	2	M45551
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	SLCO1B3 SLCO1B1	1.82e-03	32	28	2	MM14719
Pathway	REACTOME_METABOLISM_OF_STEROIDS	SLCO1B3 SLCO1B1 GGPS1	1.94e-03	126	28	3	MM15553
Pathway	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLCO1B3 SLCO1B1	2.97e-03	41	28	2	MM15075
Pathway	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLCO1B3 SLCO1B1	3.27e-03	43	28	2	M881
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	SLCO1B3 SLCO1B1	3.42e-03	44	28	2	M499
Pathway	REACTOME_METABOLISM_OF_STEROIDS	SLCO1B3 SLCO1B1 GGPS1	3.43e-03	154	28	3	M27832
Pathway	REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM	SLCO1B3 SLCO1B1	3.57e-03	45	28	2	MM14751
Pubmed	Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	18314419
Pubmed	OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	21691816
Pubmed	Structure of human drug transporters OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	37723174
Pubmed	Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	24855184
Pubmed	Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	28063966
Pubmed	Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	26474710
Pubmed	Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	25578040
Pubmed	Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	23670789
Pubmed	Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	22240838
Pubmed	Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	24989890
Pubmed	Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	17496208
Pubmed	Rotor Syndrome	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	23236639
Pubmed	Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	29944058
Pubmed	Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	17412826
Pubmed	SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	36964102
Pubmed	Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	27098745
Pubmed	Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	24740327
Pubmed	Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	21719246
Pubmed	Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	20877131
Pubmed	Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	23340295
Pubmed	Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	16534140
Pubmed	UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	31299240
Pubmed	Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	29777022
Pubmed	Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	26191226
Pubmed	In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	23886114
Pubmed	OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	21787759
Pubmed	Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	18321482
Pubmed	Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	22771883
Pubmed	Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	24194513
Pubmed	Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.	SLCO1B3 SLCO1B1	8.20e-07	2	32	2	18180273
Pubmed	Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	31047942
Pubmed	Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	26146841
Pubmed	Association study of genetic polymorphisms of drug transporters, SLCO1B1, SLCO1B3 and ABCC2, in African-Americans, Hispanics and Caucasians and olmesartan exposure.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	22695893
Pubmed	SLCO1B1, SLCO2B1, and SLCO1B3 polymorphisms and susceptibility to bladder cancer risk.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	24762081
Pubmed	Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	18492796
Pubmed	Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	28389619
Pubmed	Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	26383540
Pubmed	Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	23986199
Pubmed	Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	18413659
Pubmed	Alteration in placental expression of bile acids transporters OATP1A2, OATP1B1, OATP1B3 in intrahepatic cholestasis of pregnancy.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	22203093
Pubmed	Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	18296417
Pubmed	Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	20949553
Pubmed	Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	30955241
Pubmed	Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	20660695
Pubmed	Influence of drug formulation on OATP1B-mediated transport of paclitaxel.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	24755470
Pubmed	Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake of Glucuronide Metabolites of Androgens.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	32587096
Pubmed	Comparison of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 genes among five ethnic groups.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	26409184
Pubmed	OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	29337310
Pubmed	Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	22136368
Pubmed	Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	31967785
Pubmed	Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	28013215
Pubmed	The role of organic anion-transporting polypeptides and their common genetic variants in mycophenolic acid pharmacokinetics.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	19890249
Pubmed	HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	20051929
Pubmed	Impact of regulatory polymorphisms in organic anion transporter genes in the human liver.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	19620935
Pubmed	Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	29422623
Pubmed	Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	19400585
Pubmed	Synergistic interaction between genetics and disease on pravastatin disposition.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	24613363
Pubmed	OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	30218633
Pubmed	Association of neonatal hyperbilirubinemia in breast-fed infants with UGT1A1 or SLCOs polymorphisms.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	25391605
Pubmed	Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	10833452
Pubmed	Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	24825069
Pubmed	Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide.	SLCO1B3 SLCO1B1	2.46e-06	3	32	2	10779507
Pubmed	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.	SLCO1B3 SLCO1B1	4.92e-06	4	32	2	22294745
Pubmed	Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.	SLCO1B3 SLCO1B1	4.92e-06	4	32	2	20644253
Pubmed	Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs.	SLCO1B3 SLCO1B1	4.92e-06	4	32	2	19442037
Pubmed	Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.	SLCO1B3 SLCO1B1	4.92e-06	4	32	2	17906856
Pubmed	Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.	SLCO1B3 SLCO1B1	4.92e-06	4	32	2	21849517
Pubmed	Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.	SLCO1B3 SLCO1B1	4.92e-06	4	32	2	25280775
Pubmed	Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.	SLCO1B3 SLCO1B1	4.92e-06	4	32	2	27777271
Pubmed	Polymorphisms of the nuclear receptor pregnane X receptor and organic anion transporter polypeptides 1A2, 1B1, 1B3, and 2B1 are not associated with breast cancer risk.	SLCO1B3 SLCO1B1	8.19e-06	5	32	2	20635135
Pubmed	Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population.	SLCO1B3 SLCO1B1	8.19e-06	5	32	2	38279097
Pubmed	OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.	SLCO1B3 SLCO1B1	8.19e-06	5	32	2	24194565
Pubmed	Analysis of DNA methylation and histone modification profiles of liver-specific transporters.	SLCO1B3 SLCO1B1	1.23e-05	6	32	2	19047482
Pubmed	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.	SLCO1B3 SLCO1B1	1.23e-05	6	32	2	22232210
Pubmed	Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity.	SLCO1B3 SLCO1B1	1.23e-05	6	32	2	20212519
Pubmed	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	PKHD1 OVCH2	2.29e-05	8	32	2	19557197
Pubmed	Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.	SLCO1B3 SLCO1B1	2.29e-05	8	32	2	19129463
Pubmed	Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.	SLCO1B3 SLCO1B1	3.67e-05	10	32	2	18703564
Pubmed	The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.	SLCO1B3 SLC9A8 SLCO1B1 SLC39A8	4.22e-05	212	32	4	19521566
Pubmed	Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.	SLCO1B3 SLCO1B1	4.49e-05	11	32	2	14579113
Pubmed	Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.	SLCO1B3 SLCO1B1	4.49e-05	11	32	2	18695635
Pubmed	The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.	SLCO1B3 SLCO1B1	6.36e-05	13	32	2	11682476
Pubmed	Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.	SLCO1B3 SLCO1B1	9.76e-05	16	32	2	35307651
Pubmed	Genome-wide association meta-analysis for total serum bilirubin levels.	SLC22A18 SLCO1B1	9.76e-05	16	32	2	19414484
Pubmed	Genome-wide association of serum bilirubin levels in Korean population.	SLCO1B3 DCHS2	1.11e-04	17	32	2	20639394
Pubmed	Changes in thyroid status during perinatal development of MCT8-deficient male mice.	SLCO1B3 SLCO1B1	1.24e-04	18	32	2	23696569
Pubmed	A genome-wide assessment of variability in human serum metabolism.	ACAD11 SLCO1B1	1.39e-04	19	32	2	23281178
Pubmed	Positional cloning of the mouse saccharin preference (Sac) locus.	TAS1R2 CDK11B	1.87e-04	22	32	2	11555487
Pubmed	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.	NPR3 SLC39A8	3.28e-04	29	32	2	21909115
Pubmed	Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.	NPR3 SLC39A8	6.90e-04	42	32	2	21909110
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	SLCO1B3 ABCA5 SLCO1B1	7.41e-04	193	32	3	19343046
Cytoband	Ensembl 112 genes in cytogenetic band chr12p12	SLCO1B3 SLCO1B1	2.84e-03	113	32	2	chr12p12
Cytoband	Ensembl 112 genes in cytogenetic band chr6p12	PKHD1 RHAG	4.43e-03	142	32	2	chr6p12
GeneFamily	Solute carriers	SLC22A18 SLCO1B3 SLC9A8 SLCO1B1 SLC4A5 SLC39A8 RHAG	5.66e-07	395	24	7	752
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_DN	DGKI NPR3 ERMP1 ABCA5	2.75e-05	159	29	4	M7734
Coexpression	DESCARTES_FETAL_PLACENTA_AFP_ALB_POSITIVE_CELLS	SLCO1B3 SARDH GOLT1A SLCO1B1	3.91e-05	174	29	4	M40276
Coexpression	SERVITJA_LIVER_HNF1A_TARGETS_DN	PKHD1 PRKD3 SLCO1B3 SLCO1B1	5.51e-05	190	29	4	MM1311
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DGKI VWF TRPC1	1.26e-04	136	32	3	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC22A18 SLCO1B3 VWF	1.28e-04	137	32	3	d37f425b13bc046baa1f8619b98a16b936f88ff6
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Striatum / BrainAtlas - Mouse McCarroll V32	SLC22A18 SLCO1B3 VWF	1.28e-04	137	32	3	306b11b3b9e5fd562d845fb5eaa4ac982864efce
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Medullary_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	DCHS2 MUC4 RHAG	1.31e-04	138	32	3	7931dda2843d8bfe0e54111cc65aed1a891fe4b2
ToppCell	PCW_05-06-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PKHD1 SLC22A18 GOLT1A	1.37e-04	140	32	3	8abbd5dc799943b49cd0045d0da405c3f3d0db6b
ToppCell	PCW_05-06-Epithelial-Epithelial_ciliated\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PKHD1 SLC22A18 GOLT1A	1.37e-04	140	32	3	e4689232c473d239b07a7fbcaaa3414fbd9badea
ToppCell	droplet-Heart-4Chambers-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 VWF GOLT1A	1.65e-04	149	32	3	38890ddde0979977c8350f01497f1245ab51641a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DGKI ABCA5 TRPC1	1.74e-04	152	32	3	655d47efe0608d729801f1f01668e84c1bc0675f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1 NPR3 SLC39A8	1.78e-04	153	32	3	d6526d17826470534b766df144c74e73eb83fdad
ToppCell	RV-16._Neuronal\|RV / Chamber and Cluster_Paper	SARDH LPAR1 RHAG	1.78e-04	153	32	3	bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLCO1B3 SARDH	1.81e-04	154	32	3	a5289000597068ee8d559f89bce7bce31f35dd57
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SARDH ACAD11	1.88e-04	156	32	3	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	droplet-Liver-nan-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO1B3 SARDH PANK1	1.92e-04	157	32	3	b72c6a1ed17bfc32d9dec193d934ea82e80b6bd5
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO1B3 ACAD11 PANK1	2.03e-04	160	32	3	c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-1\|TCGA-Kidney / Sample_Type by Project: Shred V9	NPR3 VWF ACAD11	2.07e-04	161	32	3	6cacae4a759ace763597ee394cff498dc5d96f74
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NPR3 GOLT1A TRPC1	2.07e-04	161	32	3	aee74a2e7a8acd2950341963f1c04b59c7862183
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLCO1B3 SARDH	2.07e-04	161	32	3	274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A8 PANK1 SLC39A8	2.10e-04	162	32	3	6972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF PSD RHAG	2.10e-04	162	32	3	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DGKI NPR3 VWF	2.10e-04	162	32	3	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	facs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF SARDH GGPS1	2.18e-04	164	32	3	1d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF SARDH GGPS1	2.18e-04	164	32	3	bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC22A18 NPR3 VWF	2.26e-04	166	32	3	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC22A18 NPR3 VWF	2.26e-04	166	32	3	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SARDH PANK1	2.26e-04	166	32	3	8ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 PANK1 SLC39A8	2.34e-04	168	32	3	b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCell	droplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SARDH PANK1	2.34e-04	168	32	3	dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A8 PANK1 SLC39A8	2.34e-04	168	32	3	35ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCell	facs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SARDH PANK1	2.38e-04	169	32	3	922086f218135b734b7d370b871923e50141edce
ToppCell	facs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SARDH PANK1	2.38e-04	169	32	3	ee27bcfe3f9a295ec5fb0a375d77d1050e5cbaad
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 GOLT1A MUC4	2.38e-04	169	32	3	421fb287c7e439d1870b7950c5e3ca34106e014a
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 GOLT1A MUC4	2.38e-04	169	32	3	383639ec4f9d0c6255e0881edca15cdd1980a37c
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO1B3 VWF SARDH	2.43e-04	170	32	3	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO1B3 VWF SARDH	2.43e-04	170	32	3	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	droplet-Kidney-nan-3m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC9A8 SLC39A8	2.43e-04	170	32	3	dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCell	droplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SARDH PANK1	2.47e-04	171	32	3	05fcc72df50a380a913821b5781d9621df37d328
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SARDH PANK1	2.47e-04	171	32	3	48fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCell	facs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SARDH ABCA5 TRPC1	2.55e-04	173	32	3	ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DGKI NPR3 VWF	2.55e-04	173	32	3	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	facs-Marrow-T-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SARDH ABCA5 TRPC1	2.55e-04	173	32	3	19a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCell	COVID-19-kidney-PCT-S3-2\|kidney / Disease (COVID-19 only), tissue and cell type	SLCO1B3 SARDH SLCO1B1	2.60e-04	174	32	3	5aa2fb631505600f37d2b87b02def7be139dc262
ToppCell	facs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC9A8 SLC39A8	2.64e-04	175	32	3	076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCell	facs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC9A8 SLC39A8	2.64e-04	175	32	3	445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLCO1B3 SARDH SLCO1B1	2.69e-04	176	32	3	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	facs-Lung-nan-3m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC4 SLC4A5 SLC39A8	2.73e-04	177	32	3	b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCell	facs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC4 SLC4A5 SLC39A8	2.73e-04	177	32	3	e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCell	facs-Kidney-nan-18m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A18 SLC9A8 SARDH	2.73e-04	177	32	3	d4cd54c07f1e51b5485270348fb7195d53465027
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1 ERMP1 SLC39A8	2.78e-04	178	32	3	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DGKI ABCA5 TRPC1	2.78e-04	178	32	3	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA5 SLC4A5 SLC39A8	2.78e-04	178	32	3	a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA5 SLC4A5 SLC39A8	2.78e-04	178	32	3	b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DGKI NPR3 VWF	2.78e-04	178	32	3	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1 ERMP1 SLCO1B1	2.91e-04	181	32	3	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1 NPR3 SLC39A8	2.91e-04	181	32	3	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PKHD1 ABCA5 SLC39A8	2.96e-04	182	32	3	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1 ERMP1 SLCO1B1	2.96e-04	182	32	3	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PKHD1 ABCA5 SLC39A8	2.96e-04	182	32	3	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	SLC22A18 SLC9A8 SLC39A8	2.96e-04	182	32	3	bb1f815718397de96682697fcbd6014a992a28f7
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 VWF SLC39A8	3.01e-04	183	32	3	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	PKHD1 NPR3 SLC39A8	3.06e-04	184	32	3	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DGKI NPR3 VWF	3.06e-04	184	32	3	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	droplet-Marrow-nan-21m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD SLC39A8 RHAG	3.16e-04	186	32	3	6e6998f5ccb1b2628048a21e8d3053e020569aba
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.21e-04	187	32	3	dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1 DGKI ERMP1	3.26e-04	188	32	3	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 VWF SLC39A8	3.31e-04	189	32	3	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	DGKI NPR3 VWF	3.31e-04	189	32	3	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	DGKI NPR3 VWF	3.31e-04	189	32	3	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.31e-04	189	32	3	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DGKI NPR3 VWF	3.31e-04	189	32	3	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 VWF SLC39A8	3.31e-04	189	32	3	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DGKI GOLT1A ABCA5	3.41e-04	191	32	3	feec8617678b778475747ad406c80231e07fd6f7
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	DGKI NPR3 VWF	3.46e-04	192	32	3	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR3 VWF SLCO1B1	3.46e-04	192	32	3	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 VWF SLC39A8	3.46e-04	192	32	3	0b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DCHS2 NPR3 MUC4	3.46e-04	192	32	3	c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.46e-04	192	32	3	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DCHS2 NPR3 MUC4	3.46e-04	192	32	3	5d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.46e-04	192	32	3	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PKHD1 DCHS2 SLCO1B1	3.52e-04	193	32	3	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.52e-04	193	32	3	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.52e-04	193	32	3	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.52e-04	193	32	3	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.52e-04	193	32	3	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.52e-04	193	32	3	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 NPR3 VWF	3.57e-04	194	32	3	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 VWF SLC39A8	3.57e-04	194	32	3	c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1 NPR3 SLC39A8	3.57e-04	194	32	3	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	DGKI NPR3 VWF	3.57e-04	194	32	3	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	ASK440-Endothelial-Endothelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	NPR3 VWF TRPC1	3.62e-04	195	32	3	304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 VWF SLC39A8	3.62e-04	195	32	3	df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCell	343B\|World / Donor, Lineage, Cell class and subclass (all cells)	VWF MUC4 SLC39A8	3.62e-04	195	32	3	2290911fde6efacfa38b985a2541322968bee42d
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR3 VWF SLC39A8	3.68e-04	196	32	3	e386526332138e636aef2542c11316347a45689c
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PKHD1 LPAR1 TRPC1	3.73e-04	197	32	3	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	10x3'2.3-week_14-16-Hematopoietic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR3 SLC39A8 RHAG	3.73e-04	197	32	3	97a837477043902f0f5c9db850a3bfa001ea74d1
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWF SARDH GOLT1A	3.90e-04	200	32	3	fe493b0454a20498e9ada482bf55de64519f6c35
ToppCell	Parenchymal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GOLT1A MUC4 SLC39A8	3.90e-04	200	32	3	4e5b6cb014d9bcb58e13c7511c86c43e27c496e4
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MUC4 RHAG	4.76e-04	45	32	2	7be5d3e7450a767fc82742a2e5d0cc82f9518a38
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MUC4 RHAG	4.76e-04	45	32	2	668add3b0e69b851942df9c52850ed2285e08494
ToppCell	droplet-Heart-nan-24m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHAG PNPO	7.37e-04	56	32	2	55337ff90621e1fea4d747ae2559c0fa61b38dce
ToppCell	droplet-Heart-nan-24m-Hematologic-erythrocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHAG PNPO	1.25e-03	73	32	2	30374f4d30519ca8cd9582da1f9f906420e50244
Computational	Genes in the cancer module 367.	PRKD3 DGKI LPAR1	1.40e-05	29	18	3	MODULE_367
Drug	1,3-DCG	PRKD3 DGKI NPR3 LPAR1 TRPC1	1.68e-07	94	31	5	CID000150911
Drug	(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid	SLCO1B3 SLCO1B1	1.79e-06	2	31	2	ctd:C561635
Drug	iproniazid	NPR3 SARDH PNPO	2.99e-06	21	31	3	CID000003748
Drug	rifamycin SV	SLCO1B3 SLCO1B1	1.07e-05	4	31	2	ctd:C023808
Drug	microcystin-LF	SLCO1B3 SLCO1B1	1.07e-05	4	31	2	ctd:C524165
Drug	Dihydromicrocystin Lr	SLCO1B3 SLCO1B1	1.07e-05	4	31	2	CID006441227
Drug	2,2',4,4',5,6'-hexabromodiphenyl ether	SLCO1B3 SLCO1B1	1.79e-05	5	31	2	ctd:C555859
Drug	trospium chloride	SLCO1B3 SLCO1B1	2.68e-05	6	31	2	ctd:C003330
Drug	prednisolone phosphate	SLCO1B3 SLCO1B1	2.68e-05	6	31	2	CID000004896
Drug	rimonabant	PRKD3 NPR3 ERMP1 GGPS1 SLC39A8	2.73e-05	265	31	5	ctd:C089032
Drug	nateglinide	SLCO1B3 SLCO1B1	3.75e-05	7	31	2	ctd:C060142
Drug	demethylphalloin	SLCO1B3 SLCO1B1	3.75e-05	7	31	2	CID000114793
Drug	TAK-875	SLCO1B3 SLCO1B1	5.00e-05	8	31	2	ctd:C557331
Drug	Fusidic Acid	SLCO1B3 SLCO1B1	5.00e-05	8	31	2	ctd:D005672
Drug	NSC263652	SLCO1B3 SLCO1B1	5.00e-05	8	31	2	CID000429721
Drug	5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid	SLCO1B3 SLCO1B1	6.42e-05	9	31	2	ctd:C000588958
Drug	Y-S-H	SLCO1B3 SLCO1B1	8.02e-05	10	31	2	CID000449035
Drug	repaglinide	SLCO1B3 SLCO1B1	9.79e-05	11	31	2	ctd:C072379
Drug	microcystin	SLCO1B3 SLCO1B1	9.79e-05	11	31	2	ctd:C078588
Drug	AC1NQGJV	SLC22A18 VWF PNPO	1.08e-04	68	31	3	CID005195973
Drug	glimepiride	SLCO1B3 SLCO1B1	1.17e-04	12	31	2	ctd:C057619
Drug	Digocin	SLCO1B3 ABCA5 SLCO1B1	1.18e-04	70	31	3	CID000003062
Drug	conta-1(35),3,5,7(37),8,10,12,15,32(36),33-decaene-30-carboxylic acid	TAS1R2 SLCO1B3 SLCO1B1	1.28e-04	72	31	3	CID000489933
Drug	Phalloidine	SLCO1B3 SLCO1B1	1.39e-04	13	31	2	ctd:D010590
Drug	Acurea	SLCO1B3 SLCO1B1 GGPS1	1.44e-04	75	31	3	CID000003662
Drug	AC1Q7BBT	SLCO1B3 SLCO1B1	1.62e-04	14	31	2	CID000086545
Drug	Zemuron	SLC22A18 SLCO1B1	1.86e-04	15	31	2	CID000060695
Disease	Rotor syndrome	SLCO1B3 SLCO1B1	1.14e-06	2	32	2	cv:C0220991
Disease	HYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC	SLCO1B3 SLCO1B1	1.14e-06	2	32	2	C4016905
Disease	HYPERBILIRUBINEMIA, ROTOR TYPE	SLCO1B3 SLCO1B1	1.14e-06	2	32	2	237450
Disease	Rotor Syndrome	SLCO1B3 SLCO1B1	1.14e-06	2	32	2	C0220991
Disease	bilirubin metabolic disorder (implicated_via_orthology)	SLCO1B3 SLCO1B1	1.14e-05	5	32	2	DOID:2741 (implicated_via_orthology)
Disease	bilirubin metabolic disorder (is_implicated_in)	SLCO1B3 SLCO1B1	1.70e-05	6	32	2	DOID:2741 (is_implicated_in)
Disease	ecosanoids measurement	SLCO1B3 ACAD11 SLCO1B1	2.93e-05	55	32	3	EFO_0020044
Disease	deoxycholic acid glucuronide measurement	SLCO1B3 SLCO1B1	3.18e-05	8	32	2	EFO_0800575
Disease	hexadecenedioate (C16:1-DC) measurement	SLCO1B3 SLCO1B1	4.08e-05	9	32	2	EFO_0800562
Disease	X-21467 measurement	SLCO1B3 SLCO1B1	4.08e-05	9	32	2	EFO_0020007
Disease	glycochenodeoxycholate glucuronide (1) measurement	SLCO1B3 SLCO1B1	8.82e-05	13	32	2	EFO_0800474
Disease	bilirubin measurement	SLC22A18 SLCO1B3 DCHS2 SLCO1B1 RHAG	1.06e-04	442	32	5	EFO_0004570
Disease	brain measurement, neuroimaging measurement	DGKI DCHS2 ACAD11 LPAR1 SLC39A8	2.93e-04	550	32	5	EFO_0004346, EFO_0004464
Disease	alcohol use disorder measurement, alcohol dependence	PKHD1 SLC39A8	3.10e-04	24	32	2	EFO_0009458, MONDO_0007079
Disease	glycine measurement	ERMP1 SLCO1B1 SLC39A8	4.40e-04	137	32	3	EFO_0009767
Disease	cortical surface area measurement	PKHD1 DGKI DCHS2 SLC9A8 ACAD11 LPAR1 SLC39A8	4.97e-04	1345	32	7	EFO_0010736
Disease	neuroimaging measurement	PKHD1 DGKI DCHS2 ACAD11 LPAR1 SLC39A8	9.00e-04	1069	32	6	EFO_0004346
Disease	venous thromboembolism, response to antineoplastic agent	PKHD1 OVCH2	9.10e-04	41	32	2	EFO_0004286, GO_0097327
Disease	Chagas cardiomyopathy	NPR3 SLCO1B1	1.05e-03	44	32	2	EFO_0005529

Protein segments in the cluster

Peptide	Gene	Start	Entry
YSLPFKDMDKFSGLF	ABCA5	746	Q8WWZ7
GFDLMNKFLTYFPGR	CDK11B	696	P21127
AQGKFIAFYLLGMFI	ERMP1	576	Q7Z2K6
NFFLALSYFKMAGIA	ACAD11	306	Q709F0
ALLGAGLLMAFYFFR	NPR3	491	P17342
HLSMKLDAFFGIFFG	MUC4	5361	Q99102
YLMANLAAADFFAGL	LPAR1	86	Q92633
FLKGFAEFFLMGFSN	OR14L1P	6	Q8NHC6
GFFGMYDKILLFRHD	PRKD3	101	O94806
FGLAVGLMQLFSDYK	GGPS1	156	O95749
MLLLKGFGKDGFRFF	PNPO	96	Q9NVS9
FAMFLGATEFYLLAA	OR2AP1	101	Q8NGE2
GMFLETYGFFSLFKG	GOLT1A	86	Q6ZVE7
MESFFLGETLKYLFL	MAN1B1	656	Q9UKM7
LLYFLLSDGKFFKMN	DCHS2	1226	Q6V1P9
VVSLFFGSGAFMYLK	OR8B12	246	Q8NGG6
KMFYAGAAFSDFLQR	DGKI	561	O75912
YLKMAAGAFAAGLLN	OR5F1	141	O95221
YFGAVGALLELFKMT	PANK1	581	Q8TE04
AGEYLKFFVFTGMTL	PSD	591	A5PKW4
YDIALLKMAGAFQFG	OVCH2	141	Q7RTZ1
LDYFLKMFFGSAALG	SLC9A8	261	Q9Y2E8
GFLAFKNFDYGAMLH	PKHD1	3146	P08F94
FASGMFLGGYIIKKF	SLCO1B1	386	Q9Y6L6
LEAAQAGYLMSFFGL	SLC22A18	271	Q96BI1
FDMSYFGKFYLVGLD	SARDH	571	Q9UL12
DFGKFLGMFLLVLFS	TRPC1	536	P48995
GMAHYLTFDGLKYLF	VWF	871	P04275
GFKMFLAALSFSYIA	SLCO1B3	26	Q9NPD5
IFVGFGFLMTFLKKY	RHAG	61	Q02094
LFDFSKGNGLDYMEF	SLC4A5	591	Q9BY07
LLLSVVGFSFAYMGK	TAS1R2	736	Q8TE23
FALAGGMFLYISLAD	SLC39A8	396	Q9C0K1