Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion binding

WT1 ZSWIM2 CHORDC1 TRIM24 TRIM5 CRIP2 RNF151 GDA P2RX7 PRICKLE3 SYTL3 GLI2 ITGB1BP2 ADAMTS20 KDM1B MARCHF4 RBX1

1.24e-068919717GO:0008270
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1 WDR24

3.13e-064739712GO:0004842
GeneOntologyMolecularFunctionacyltransferase activity

ZDHHC21 RNF186 ZSWIM2 TRIM24 ZDHHC4 TRIM5 RNF151 ZDHHC23 RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1 WDR24

4.77e-067759715GO:0016746
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1 WDR24

7.01e-065129712GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1 WDR24

1.03e-055329712GO:0016755
GeneOntologyMolecularFunctionubiquitin protein ligase activity

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 SHPRH RNF38 TOPORS RBX1 WDR24

1.33e-053729710GO:0061630
GeneOntologyMolecularFunctiontransition metal ion binding

WT1 ZSWIM2 CHORDC1 TRIM24 TRIM5 CRIP2 RNF151 GDA P2RX7 PRICKLE3 SYTL3 GLI2 ITGB1BP2 ADAMTS20 KDM1B MARCHF4 MUC2 RBX1

1.47e-0511899718GO:0046914
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 SHPRH RNF38 TOPORS RBX1 WDR24

2.38e-053989710GO:0061659
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1B LRP1 LRP2

5.94e-0516973GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1B LRP1 LRP2

1.39e-0421973GO:0030228
GeneOntologyMolecularFunctionprotein-cysteine S-palmitoyltransferase activity

ZDHHC21 ZDHHC4 ZDHHC23

2.66e-0426973GO:0019706
GeneOntologyMolecularFunctionprotein-cysteine S-acyltransferase activity

ZDHHC21 ZDHHC4 ZDHHC23

2.66e-0426973GO:0019707
GeneOntologyMolecularFunctionS-acyltransferase activity

ZDHHC21 ZDHHC4 ZDHHC23

4.10e-0430973GO:0016417
GeneOntologyMolecularFunctionpalmitoyltransferase activity

ZDHHC21 ZDHHC4 ZDHHC23

7.66e-0437973GO:0016409
GeneOntologyMolecularFunctioncargo receptor activity

FOLR1 LRP1B LRP1 LRP2

7.84e-0485974GO:0038024
GeneOntologyMolecularFunctionLIM domain binding

ISL1 LDB1

8.22e-049972GO:0030274
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

DKK1 LRP1 LRP2

8.95e-0439973GO:0070325
GeneOntologyMolecularFunctionATP-dependent diacylglycerol kinase activity

DGKD DGKK

1.25e-0311972GO:0004143
GeneOntologyBiologicalProcessanimal organ formation

FOLR1 WT1 ISL1 DKK1 GLI2 LRP2

1.81e-0678976GO:0048645
GeneOntologyBiologicalProcessspinal cord motor neuron cell fate specification

ISL2 ISL1 GLI2

1.62e-0511973GO:0021520
GeneOntologyBiologicalProcessheart formation

FOLR1 ISL1 DKK1 LRP2

2.41e-0536974GO:0060914
GeneOntologyBiologicalProcessheart field specification

ISL1 DKK1 LRP2

6.54e-0517973GO:0003128
GeneOntologyBiologicalProcessvisceral motor neuron differentiation

ISL2 ISL1

6.55e-053972GO:0021524
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

USP53 RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 USP31 RNF141 SHPRH RNF38 TOPORS MARCHF4 ZRANB1 RBX1 WDR24

7.12e-0510099715GO:0070647
GeneOntologyCellularComponentmucus layer

MUC2 MUC5AC

6.37e-053972GO:0070701
MousePhenoabnormal uvea morphology

COL2A1 FLNA CD46 TGFA CHIC2 TRPM3 MED12L LTBP2

5.25e-05241778MP:0005197
MousePhenodecreased hepatocyte number

RB1 MDK LRP1

6.97e-0515773MP:0000606
MousePhenoflat forehead

RB1 LRP2

8.95e-053772MP:0030047
MousePhenoabnormal forehead shape

COL2A1 RB1 LRP2

1.03e-0417773MP:0030045
MousePhenoabnormal anterior uvea morphology

COL2A1 FLNA TGFA CHIC2 TRPM3 MED12L LTBP2

1.10e-04199777MP:0005194
DomainZnf_RING

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 KMT2D RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1

1.10e-073269612IPR001841
DomainZF_RING_2

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 KMT2D RNF141 SHPRH RNF38 TOPORS RBX1

3.76e-072989611PS50089
DomainRING

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 KMT2D RNF141 SHPRH RNF38 TOPORS RBX1

4.73e-073059611SM00184
Domain-

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 KMT2D SYTL3 RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1

4.96e-0744996133.30.40.10
DomainZnf_RING/FYVE/PHD

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 KMT2D SYTL3 RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1

6.36e-074599613IPR013083
Domainzf-C3HC4

ZSWIM2 TRIM24 TRIM5 RNF151 RNF141 RNF38 TOPORS MARCHF4 RBX1

2.21e-06223969PF00097
DomainZF_RING_1

RNF186 ZSWIM2 TRIM24 TRIM5 RNF151 KMT2D RNF141 SHPRH RNF38 TOPORS

2.50e-062919610PS00518
DomainSCAN

ZNF165 ZNF232 ZSCAN32 ZSCAN30 ZSCAN16

1.00e-0556965SM00431
DomainSCAN_BOX

ZNF165 ZNF232 ZSCAN32 ZSCAN30 ZSCAN16

1.19e-0558965PS50804
DomainSCAN

ZNF165 ZNF232 ZSCAN32 ZSCAN30 ZSCAN16

1.19e-0558965PF02023
DomainSCAN_dom

ZNF165 ZNF232 ZSCAN32 ZSCAN30 ZSCAN16

1.19e-0558965IPR003309
DomainRetrov_capsid_C

ZNF165 ZNF232 ZSCAN32 ZSCAN30 ZSCAN16

1.30e-0559965IPR008916
DomainZnf_RING_CS

RNF186 TRIM24 TRIM5 RNF151 RNF141 SHPRH TOPORS

2.11e-05163967IPR017907
DomainCHORD_dom

CHORDC1 ITGB1BP2

2.61e-052962IPR007051
DomainDUF5050

LRP1B LRP1

2.61e-052962IPR032485
DomainCHORD

CHORDC1 ITGB1BP2

2.61e-052962PF04968
DomainDUF5050

LRP1B LRP1

2.61e-052962PF16472
DomainCHORD

CHORDC1 ITGB1BP2

2.61e-052962PS51401
DomainZINC_FINGER_C2H2_2

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZC3H7B ZBTB18

4.06e-057759614PS50157
DomainZINC_FINGER_C2H2_1

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZC3H7B ZBTB18

4.18e-057779614PS00028
Domain-

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZBTB18

4.34e-0567996133.30.160.60
DomainTIL_dom

LRP2 MUC2 MUC5AC

4.60e-0514963IPR002919
DomainLdl_recept_b

LRP1B LRP1 LRP2

4.60e-0514963PF00058
DomainLDLRB

LRP1B LRP1 LRP2

4.60e-0514963PS51120
DomainZnf_C2H2-like

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZC3H7B ZBTB18

5.42e-057969614IPR015880
DomainZnf_C2H2/integrase_DNA-bd

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZBTB18

5.43e-056949613IPR013087
DomainLY

LRP1B LRP1 LRP2

5.73e-0515963SM00135
DomainLDLR_classB_rpt

LRP1B LRP1 LRP2

5.73e-0515963IPR000033
DomainZnf_C2H2

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZC3H7B ZBTB18

6.12e-058059614IPR007087
DomainZnF_C2H2

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZC3H7B ZBTB18

6.37e-058089614SM00355
Domainzf-DHHC

ZDHHC21 ZDHHC4 ZDHHC23

2.16e-0423963PF01529
Domainzf-C2H2

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZBTB18

2.23e-046939612PF00096
DomainDHHC

ZDHHC21 ZDHHC4 ZDHHC23

2.79e-0425963PS50216
DomainZnf_DHHC_palmitoyltrfase

ZDHHC21 ZDHHC4 ZDHHC23

2.79e-0425963IPR001594
DomaincEGF

LRP1B LRP1 LRP2

3.14e-0426963IPR026823
DomaincEGF

LRP1B LRP1 LRP2

3.14e-0426963PF12662
DomainWxxW_domain

MUC2 MUC5AC

3.87e-046962IPR025155
DomainMucin2_WxxW

MUC2 MUC5AC

3.87e-046962PF13330
DomainLIM

ISL2 ISL1 CRIP2 PRICKLE3

4.39e-0469964PF00412
Domain-

ISL2 ISL1 CRIP2 PRICKLE3

4.64e-04709642.10.110.10
DomainEGF

LRP1B TGFA LRP1 LRP2 LTBP2

4.83e-04126965PF00008
DomainZnf_LIM

ISL2 ISL1 CRIP2 PRICKLE3

4.89e-0471964IPR001781
DomainLIM_DOMAIN_1

ISL2 ISL1 CRIP2 PRICKLE3

4.89e-0471964PS00478
DomainLIM_DOMAIN_2

ISL2 ISL1 CRIP2 PRICKLE3

4.89e-0471964PS50023
DomainLIM

ISL2 ISL1 CRIP2 PRICKLE3

4.89e-0471964SM00132
DomainVWFC_1

COL2A1 MUC2 MUC5AC

8.31e-0436963PS01208
DomainVWC

COL2A1 MUC2 MUC5AC

9.74e-0438963SM00214
DomainVWFC_2

COL2A1 MUC2 MUC5AC

9.74e-0438963PS50184
DomainEGF_CA

LRP1B LRP1 LRP2 LTBP2

1.01e-0386964PF07645
Domain-

LRP1B LRP1 LRP2

1.05e-03399632.120.10.30
DomainLDLR_class-A_CS

LRP1B LRP1 LRP2

1.13e-0340963IPR023415
DomainNa_channel_asu

SCN5A SCN7A

1.15e-0310962IPR001696
DomainDAGK_acc

DGKD DGKK

1.15e-0310962PF00609
DomainDiacylglycerol_kin_accessory

DGKD DGKK

1.15e-0310962IPR000756
DomainNa_trans_assoc

SCN5A SCN7A

1.15e-0310962IPR010526
DomainDAGKa

DGKD DGKK

1.15e-0310962SM00045
DomainNa_trans_assoc

SCN5A SCN7A

1.15e-0310962PF06512
DomainVWF_dom

COL2A1 MUC2 MUC5AC

1.31e-0342963IPR001007
DomainEGF_Ca-bd_CS

LRP1B LRP1 LRP2 LTBP2

1.58e-0397964IPR018097
DomainLdl_recept_a

LRP1B LRP1 LRP2

1.60e-0345963PF00057
DomainTIL

MUC2 MUC5AC

1.67e-0312962PF01826
DomainC8

MUC2 MUC5AC

1.67e-0312962PF08742
DomainEGF_CA

LRP1B LRP1 LRP2 LTBP2

1.70e-0399964PS01187
Domain-

LRP1B LRP1 LRP2

1.70e-03469634.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP1B LRP1 LRP2

1.70e-0346963IPR011042
DomainASX_HYDROXYL

LRP1B LRP1 LRP2 LTBP2

1.76e-03100964PS00010
DomainZnF_C3H1

TRMT1 RBM22 ZC3H7B

1.92e-0348963SM00356
DomainLDLRA_1

LRP1B LRP1 LRP2

1.92e-0348963PS01209
DomainZnf_C3HC4_RING-type

TRIM5 RNF141 RNF38 TOPORS MARCHF4

1.94e-03172965IPR018957
DomainFERM-adjacent

EPB41L5 EPB41L2

1.97e-0313962IPR014847
DomainUnchr_dom_Cys-rich

MUC2 MUC5AC

1.97e-0313962IPR014853
DomainC8

MUC2 MUC5AC

1.97e-0313962SM00832
DomainFA

EPB41L5 EPB41L2

1.97e-0313962SM01195
DomainFA

EPB41L5 EPB41L2

1.97e-0313962PF08736
Domainzf-CCCH

TRMT1 RBM22 ZC3H7B

2.04e-0349963PF00642
DomainLDLRA_2

LRP1B LRP1 LRP2

2.04e-0349963PS50068
DomainLDrepeatLR_classA_rpt

LRP1B LRP1 LRP2

2.04e-0349963IPR002172
DomainLDLa

LRP1B LRP1 LRP2

2.04e-0349963SM00192
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1B LRP1 LRP2 LTBP2

2.18e-03106964IPR000152
DomainCS

CHORDC1 ITGB1BP2

2.29e-0314962PF04969
DomainDAGKc

DGKD DGKK

2.29e-0314962SM00046
DomainDiacylglycerol_kinase_cat_dom

DGKD DGKK

2.63e-0315962IPR001206
DomainDAGK_cat

DGKD DGKK

2.63e-0315962PF00781
DomainDAGK

DGKD DGKK

2.63e-0315962PS50146
DomainVWD

MUC2 MUC5AC

2.99e-0316962SM00216
DomainCS_dom

CHORDC1 ITGB1BP2

2.99e-0316962IPR007052
DomainVWF_type-D

MUC2 MUC5AC

2.99e-0316962IPR001846
DomainVWFD

MUC2 MUC5AC

2.99e-0316962PS51233
DomainCS

CHORDC1 ITGB1BP2

2.99e-0316962PS51203
DomainVWD

MUC2 MUC5AC

2.99e-0316962PF00094
DomainZnf_CCCH

TRMT1 RBM22 ZC3H7B

3.31e-0358963IPR000571
DomainZF_C3H1

TRMT1 RBM22 ZC3H7B

3.31e-0358963PS50103
DomainNAD/diacylglycerol_kinase

DGKD DGKK

3.38e-0317962IPR016064
DomainEGF_CA

LRP1B LRP1 LRP2 LTBP2

3.62e-03122964SM00179
DomainEGF_extracell

LRP1B LRP2 LTBP2

3.64e-0360963IPR013111
DomainEGF_2

LRP1B LRP2 LTBP2

3.64e-0360963PF07974
DomainCTCK_1

MUC2 MUC5AC

3.79e-0318962PS01185
DomainEGF-like_Ca-bd_dom

LRP1B LRP1 LRP2 LTBP2

3.84e-03124964IPR001881
DomainTSP_1

THSD7B ADAMTSL3 ADAMTS20

4.18e-0363963PF00090
DomainVWC_out

MUC2 MUC5AC

4.22e-0319962SM00215
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

FOLR1 LRP1B LRP1 LRP2

1.85e-081197424639464
Pubmed

The nuclear LIM domain interactor NLI mediates homo- and heterodimerization of LIM domain transcription factors.

ISL2 ISL1 LDB1

7.30e-0779739452425
Pubmed

Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development.

FLNA RB1 ISL1

1.75e-06997325953344
Pubmed

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.

ISL2 ISL1 GLI2

1.75e-06997310725236
Pubmed

A regulatory network to segregate the identity of neuronal subtypes.

ISL2 ISL1 LDB1

1.75e-06997318539116
Pubmed

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.

ISL2 ISL1 GLI2

1.75e-06997312361967
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

MDK LRP1 LRP2

1.75e-06997310772929
Pubmed

Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube.

ISL2 ISL1 GLI2

1.75e-06997316950124
Pubmed

Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.

ISL2 ISL1 GLI2

2.49e-061097312812795
Pubmed

Gli1 can rescue the in vivo function of Gli2.

ISL2 ISL1 GLI2

2.49e-061097311748151
Pubmed

The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression.

ISL2 ISL1 GLI2

2.49e-061097330843071
Pubmed

Regulation of motor neuron specification by phosphorylation of neurogenin 2.

ISL2 ISL1 LDB1

2.49e-061097318400164
Pubmed

Single-stranded DNA binding proteins are required for LIM complexes to induce transcriptionally active chromatin and specify spinal neuronal identities.

ISL2 ISL1 LDB1

3.41e-061197326965372
Pubmed

PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant.

ISL2 ISL1 GLI2

3.41e-061197328673820
Pubmed

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.

ISL2 ISL1 GLI2

5.89e-06139739636069
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1B LRP1 LRP2

7.49e-061497315082773
Pubmed

Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.

ISL2 ISL1 GLI2

7.49e-061497319666503
Pubmed

Islet-to-LMO stoichiometries control the function of transcription complexes that specify motor neuron and V2a interneuron identity.

ISL2 ISL1 LDB1

7.49e-061497319666821
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1B LRP1

7.70e-06297215963947
Pubmed

Chp-1 and melusin, two CHORD containing proteins in vertebrates.

CHORDC1 ITGB1BP2

7.70e-06297212965203
Pubmed

beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.

APOH LRP2

7.70e-0629729727058
Pubmed

Premature ligand-receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1.

MDK LRP1

7.70e-06297221212259
Pubmed

Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.

MDK LRP1

7.70e-06297230647120
Pubmed

Mucolytic activity of bacterial and human chitinases.

MUC2 MUC5AC

7.70e-06297217321686
Pubmed

Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.

MUC2 MUC5AC

7.70e-06297220731025
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

MUC2 MUC5AC

7.70e-06297223832517
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.

MUC2 MUC5AC

7.70e-06297223832516
Pubmed

Co-localization of a novel transcriptional repressor simiRP58 with RP58.

ZBTB42 ZBTB18

7.70e-06297218262495
Pubmed

RING Finger Protein 38 Mediates LIM Domain Binding 1 Degradation and Regulates Cell Growth in Colorectal Cancer.

LDB1 RNF38

7.70e-06297232021282
Pubmed

Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.

MUC2 MUC5AC

7.70e-06297217203232
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

7.70e-06297234445520
Pubmed

[Dickkopf-1 inhibits the secretion of MUC5AC induced by Mycoplasma pneumoniae P1-C in mouse lung epithelial cells].

DKK1 MUC5AC

7.70e-06297236738214
Pubmed

Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma.

TGFA MUC5AC

7.70e-06297236068759
Pubmed

Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.

MUC2 MUC5AC

7.70e-06297212527922
Pubmed

Tumour suppressor gene mutations in humans and mice: parallels and contrasts.

RB1 WT1

7.70e-0629729843483
Pubmed

Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1).

WT1 MDK

7.70e-0629728950987
Pubmed

In vivo glycosylation of mucin tandem repeats.

MUC2 MUC5AC

7.70e-06297211445551
Pubmed

Islet1 and its co-factor Ldb1 are expressed in quiescent cells of mouse intestinal epithelium.

ISL1 LDB1

7.70e-06297224755910
Pubmed

Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.

MUC2 MUC5AC

7.70e-06297214594655
Pubmed

Combination of MUC5ac and WT-1 immunohistochemistry is useful in distinguishing pancreatic ductal carcinoma from ovarian serous carcinoma in effusion cytology.

WT1 MUC5AC

7.70e-06297219856421
Pubmed

Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.

MUC2 MUC5AC

7.70e-06297212820724
Pubmed

Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells.

COL2A1 ISL2 ISL1

9.34e-061597325794678
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

HAUS6 EPB41L5 GBA2 TRPM3 MED12L

9.75e-0610197510997877
Pubmed

Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.

ISL2 ISL1 GLI2

1.15e-051697328800946
Pubmed

Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.

WT1 ISL1 TRIM5

1.15e-051697329859889
Pubmed

Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain.

ISL2 ISL1 GLI2

1.15e-051697317026983
Pubmed

Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.

TRIM24 TRIM5 RNF141 RNF38 RBX1

1.18e-0510597522493164
Pubmed

All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3.

ISL2 ISL1 GLI2

1.66e-051897314723851
Pubmed

Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.

WT1 ISL2 ISL1

1.66e-051897330456369
Pubmed

Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice.

ISL2 ISL1 GLI2

1.97e-051997328817564
Pubmed

Mutually exclusive mutation profiles define functionally related genes in muscle invasive bladder cancer.

RB1 KMT2D

2.31e-05397235073341
Pubmed

Differential Islet-1 expression among lumbosacral spinal motor neurons in prenatal mouse.

ISL2 ISL1

2.31e-05397219236857
Pubmed

KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.

RB1 KMT2D

2.31e-05397234724040
Pubmed

DKK1 suppresses WWP2 to enhance bortezomib resistance in multiple myeloma via regulating GLI2 ubiquitination.

DKK1 GLI2

2.31e-05397234546340
Pubmed

Differences in the expression of mucins in various forms of cystitis glandularis.

MUC2 MUC5AC

2.31e-05397217659847
Pubmed

Initial trajectories of sensory axons toward laminar targets in the developing mouse spinal cord.

ISL2 ISL1

2.31e-0539729100133
Pubmed

Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.

MUC2 MUC5AC

2.31e-05397218825309
Pubmed

ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis.

ISL2 ISL1

2.31e-05397226951213
Pubmed

Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.

MUC2 MUC5AC

2.31e-05397218300795
Pubmed

Islet-1 expression in thoracic spinal motor neurons in prenatal mouse.

ISL2 ISL1

2.31e-05397221651972
Pubmed

LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.

ISL1 LDB1

2.31e-05397227941246
Pubmed

Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.

MUC2 MUC5AC

2.31e-05397217333267
Pubmed

Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.

RB1 TRIM24

2.31e-05397238514847
Pubmed

Emergence of sigh rhythmogenesis in the embryonic mouse.

ISL2 ISL1

2.31e-05397224591570
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC2 MUC5AC

2.31e-05397219718741
Pubmed

Glycine release from radial cells modulates the spontaneous activity and its propagation during early spinal cord development.

ISL2 ISL1

2.31e-05397220053920
Pubmed

Reactive oxygen species regulate Pseudomonas aeruginosa lipopolysaccharide-induced MUC5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alpha signaling pathways in human airway epithelial cells.

TGFA MUC5AC

2.31e-05397218073139
Pubmed

WT1 promotes cell proliferation in non-small cell lung cancer cell lines through up-regulating cyclin D1 and p-pRb in vitro and in vivo.

RB1 WT1

2.31e-05397223936312
Pubmed

The mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing.

MDK KMT2D

2.31e-05397225355294
Pubmed

Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.

ISL1 LDB1

2.31e-05397218583962
Pubmed

Gene expression profiling of colorectal mucinous adenocarcinomas.

MUC2 MUC5AC

2.31e-05397220485009
Pubmed

Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons.

ISL2 ISL1

2.31e-05397221339182
Pubmed

Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.

MUC2 MUC5AC

2.31e-05397223464473
Pubmed

Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.

MUC2 MUC5AC

2.31e-05397224920497
Pubmed

Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'.

APOH LRP1

2.31e-05397212807892
Pubmed

Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse.

ISL2 ISL1 GLI2

2.32e-052097328379358
Pubmed

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.

ISL2 ISL1 GLI2

2.70e-052197322007132
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1B LRP1 LRP2

2.70e-052197321337463
Pubmed

Arx is required for normal enteroendocrine cell development in mice and humans.

ISL2 ISL1 MUC2

3.12e-052297322387004
Pubmed

Cbln1 regulates axon growth and guidance in multiple neural regions.

ISL2 ISL1 GLI2

3.12e-052297336395107
Pubmed

Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS.

ISL2 ISL1 GLI2

3.12e-052297321775418
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

RB1 WT1 ISL2 ISL1 ZNF232 TRIM24 TRIM5 ANKRD53 ZSCAN32 LDB1 PRICKLE3

3.41e-05877971120211142
Pubmed

Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.

LRP1B PTGFRN GLI2

3.58e-052397320932654
Pubmed

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.

ISL2 ISL1 GLI2

3.58e-052397316459298
Pubmed

Aberrant expression of tumor suppressor genes and their association with chimeric oncogenes in pediatric acute lymphoblastic leukemia.

RB1 WT1

4.60e-05497215878620
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

4.60e-05497212413896
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC2 MUC5AC

4.60e-05497225638393
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC2 MUC5AC

4.60e-05497222269464
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

MUC2 MUC5AC

4.60e-05497222691042
Pubmed

Robo1 and 2 Repellent Receptors Cooperate to Guide Facial Neuron Cell Migration and Axon Projections in the Embryonic Mouse Hindbrain.

ISL2 ISL1

4.60e-05497230685539
Pubmed

Necdin plays a role in the serotonergic modulation of the mouse respiratory network: implication for Prader-Willi syndrome.

ISL2 ISL1

4.60e-05497218272695
Pubmed

KPC2 relocalizes HOXA2 to the cytoplasm and decreases its transcriptional activity.

ISL2 ISL1

4.60e-05497226303204
Pubmed

LPS increases MUC5AC by TACE/TGF-α/EGFR pathway in human intrahepatic biliary epithelial cell.

TGFA MUC5AC

4.60e-05497224027752
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2

4.60e-0549727775583
Pubmed

Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells.

MUC2 MUC5AC

4.60e-05497212391274
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC2 MUC5AC

4.60e-05497223807779
Pubmed

Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification.

ISL2 ISL1

4.60e-05497222025611
Pubmed

A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis.

ISL2 ISL1

4.60e-05497217468498
Pubmed

Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8-deficient mice.

ISL2 ISL1

4.60e-0549729486801
Pubmed

Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons.

ISL2 ISL1

4.60e-05497227161150
InteractionZNF446 interactions

ZNF165 ISL2 ZNF232 RGS3 ZSCAN32 LDB1 ZSCAN30 ZSCAN16

1.01e-0888978int:ZNF446
InteractionZSCAN30 interactions

ZNF232 RGS3 ZSCAN32 ZSCAN30

6.61e-0715974int:ZSCAN30
InteractionZNF460 interactions

ZNF337 TRIM24 RGS3 RBM22 PRICKLE3 TOPORS ZRANB1

4.66e-06138977int:ZNF460
InteractionLHX1 interactions

ISL2 ISL1 TRIM24 KMT2D LDB1 DGKK

1.04e-05103976int:LHX1
InteractionZNF397 interactions

ZNF232 RGS3 ZSCAN32 ZNF26 ZSCAN30

1.21e-0562975int:ZNF397
InteractionZNF444 interactions

ZNF232 ZSCAN32 RBM22 ZSCAN30 LTBP2 ZRANB1

1.23e-05106976int:ZNF444
InteractionAPOH interactions

FLNA APOH LRP2 ZRANB1

1.26e-0530974int:APOH
InteractionSCAND1 interactions

RNF186 ZNF165 ZNF232 ZSCAN32 ZSCAN16

2.20e-0570975int:SCAND1
InteractionLRP1B interactions

LRP1B LRP1 LRP2 ZRANB1 RBX1

5.63e-0585975int:LRP1B
InteractionZSCAN32 interactions

ZNF232 ZSCAN32 ZSCAN30 ZSCAN16

6.46e-0545974int:ZSCAN32
InteractionMDK interactions

EPB41L5 MDK LRP1 LRP2 ZRANB1

7.81e-0591975int:MDK
InteractionBCL9L interactions

ISL2 ISL1 LDB1 ZRANB1

8.34e-0548974int:BCL9L
GeneFamilyRing finger proteins

RNF186 TRIM24 TRIM5 RNF151 RNF141 SHPRH RNF38 TOPORS MARCHF4 RBX1

2.22e-07275761058
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF165 ZNF337 WT1 ZFPM1 ZNF232 ZBTB42 ZNF7 ZSCAN32 ZNF26 ZSCAN30 GLI2 ZSCAN16 ZBTB18

8.31e-06718761328
GeneFamilyLow density lipoprotein receptors

LRP1B LRP1 LRP2

1.98e-0513763634
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC21 ZDHHC4 ZDHHC23

1.36e-042476376
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKD DGKK

7.68e-04107621178
GeneFamilyLIM class homeoboxes

ISL2 ISL1

1.12e-0312762522
GeneFamilyCD molecules|Mucins

MUC2 MUC5AC

3.48e-0321762648
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 WT1 ADAMTSL3 ZBTB42 SCN7A MSS51

9.56e-07150976909ccab92855f5f049dc29593aadab1ea973297b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 GLI2 SCN7A LRP1 LTBP2 EPB41L2

1.85e-061689764b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 GLI2 SCN7A LRP1 LTBP2 EPB41L2

2.05e-061719765d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 PLA2R1 GLI2 LRP1 LTBP2 EPB41L2

2.34e-06175976795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR2 FLNA DGKD GLI2 ITGB1BP2 SCN5A

2.34e-06175976d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR2 FLNA DGKD GLI2 ITGB1BP2 SCN5A

2.34e-06175976454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 PTGFRN TGFA ZNF7 NDST3 SCN7A

2.94e-06182976e3248d108b51c49ca2c978636e13017e23b53860
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 LRP1B TRPM3 DGKK LRP2 ADAMTS20

3.13e-061849762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 LRP1B TRPM3 DGKK LRP2 ADAMTS20

3.13e-06184976ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL2A1 LRP1B TRPM3 DGKK LRP2 ADAMTS20

3.13e-061849762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 WT1 ISL1 NDST3 TMEM47 SCN7A

3.23e-0618597611fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL3 GLI2 SCN7A LRP1 LTBP2 EPB41L2

5.05e-06200976389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL3 GLI2 SCN7A LRP1 LTBP2 EPB41L2

5.05e-06200976cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL3 GLI2 SCN7A LRP1 LTBP2 EPB41L2

5.05e-06200976cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL2A1 ADAMTSL3 SCN7A LRP1 LTBP2 EPB41L2

5.05e-06200976c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

USP53 ADAMTSL3 GLI2 SCN7A LRP1 LTBP2

5.05e-06200976311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WT1 ADAMTSL3 GLI2 SCN7A LRP1 EPB41L2

5.05e-0620097674e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

VIPR2 DGKD ADAMTSL3 NDST3 LRP1 EPB41L2

5.05e-06200976bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPB41L5 RNF151 TMEM47 LRP1 MUC5AC

2.20e-051549755ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WT1 ISL1 DKK1 TRPM3 LRP2

3.44e-051699750cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WT1 ISL1 DKK1 TRPM3 LRP2

3.44e-051699756937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHCHD5 ZDHHC4 ELMO3 SYTL3 DGKK

3.53e-0517097528fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHCHD5 ZDHHC4 ELMO3 SYTL3 DGKK

3.53e-05170975239cb4b801b2d71a6facb386f2684c0851504151
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RB1 TRMT1 ZFPM1 ZBTB42 GDA

3.84e-05173975c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RB1 TRMT1 ZFPM1 ZBTB42 GDA

3.84e-05173975a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CHORDC1 LRP1B GDA TRPM3 LRP2

4.17e-0517697536f77d878a53b30465b0dea8333a3865dba75613
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 GPR173 ADAMTSL3 SCN7A EPB41L2

4.28e-05177975bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL2A1 GPR173 ISL1 MDK MARCHF4

4.52e-05179975f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic-Meg|bone_marrow / Manually curated celltypes from each tissue

COL2A1 WT1 NDST3 DKK1 MED12L

4.64e-0518097544ba37bead1ac39bce4d3eef00961063c50ced0d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 WT1 TMEM47 LRP1 EPB41L2

4.76e-05181975a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 WT1 TMEM47 LRP1 EPB41L2

4.76e-05181975526e858a848470b6d2d5248788004d9735ed3add
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RB1 TMEM86B ZFPM1 ZBTB42 LDB1

4.89e-051829754a85429d365c4b2d73fc921f261b4b7635ac40bd
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RB1 TMEM86B ZFPM1 ZBTB42 LDB1

4.89e-0518297553213af34af3337f5edc734d3b7b79e4349eac0d
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RB1 TMEM86B ZFPM1 ZBTB42 LDB1

4.89e-051829757909089ed6325c44edd6f9b7e8b1d542398222ea
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WT1 ISL1 DKK1 LRP2 MUC5AC

5.02e-051839759d5a363fbe6f0a1668c9d584df65ee1c283349c7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WT1 ISL1 DKK1 LRP2 MUC5AC

5.02e-05183975c5caac6ed6c8d67f5c336281d9fd903976509445
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 PLA2R1 GLI2 LRP1 EPB41L2

5.15e-05184975e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL2A1 ZSCAN32 KMT2D ELMO3 PRICKLE3

5.28e-05185975636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ISL1 MDK LRP1B TRPM3 SYTL3

5.42e-051869758915436d09775f2828a7678af203b1082b36e21c
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VIPR2 ZFPM1 TRIM24 CHIC2 TOPORS

5.42e-0518697510565fce7e1b4ec88bc8e1ed6410a83800be5014
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOLR1 MDK CRIP2 ELMO3 MUC5AC

5.56e-0518797582bbc107f58c623f3b90430c90c562624a12abef
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMCX4 ZDHHC23 LRP2 ZBTB18 MUC5AC

5.56e-05187975f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WT1 ISL1 SCN7A LRP2 IFNL2

5.70e-0518897500c5259bcb83218b7d44f4d585d9b68ef49763ab
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR2 ADAMTSL3 GLI2 LRP1 EPB41L2

5.70e-05188975ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 GPR173 SCN7A LRP1 LTBP2

5.85e-05189975f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR2 ADAMTSL3 GLI2 LRP1 EPB41L2

5.99e-05190975efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIR1 APOH FAM221B SYTL3 WDR12

5.99e-051909752f5460fa028dfe6b80dd024063a4513dc532a94d
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

USP53 ADAMTSL3 GLI2 SCN7A LTBP2

5.99e-051909753a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

ADAMTSL3 GLI2 SCN7A LTBP2 EPB41L2

6.15e-05191975f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WT1 CHIC2 GLI2 LRP1 EPB41L2

6.15e-051919751caf726bd07fdca389e678fc16304a6ef1790423
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

VIPR2 GPR173 ADAMTSL3 TMEM47 GLI2

6.15e-0519197578c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellASK440-Mesenchymal-Fibroblast|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

ADAMTSL3 GLI2 SCN7A LTBP2 EPB41L2

6.15e-05191975387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WT1 CHIC2 GLI2 LRP1 EPB41L2

6.15e-051919753d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 ADAMTSL3 GLI2 SCN7A LTBP2

6.15e-051919756688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCelldroplet-Kidney-nan-18m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISL2 ISL1 SCN7A LRP1 LTBP2

6.30e-0519297538d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL3 PTGFRN PLA2R1 GLI2 SCN7A

6.30e-051929758937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISL2 ISL1 SCN7A LRP1 LTBP2

6.30e-0519297504d155897ed075c359933080e36a4ab2150b6e9f
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL3 PTGFRN PLA2R1 GLI2 SCN7A

6.30e-05192975e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 ADAMTSL3 GLI2 SCN7A LTBP2

6.30e-0519297599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL3 PTGFRN PLA2R1 GLI2 SCN7A

6.30e-05192975ac1477433704573f95111eee6263b93668d2845e
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ADAMTSL3 SCN7A LRP1 LTBP2 EPB41L2

6.30e-0519297560b1312e84f6d6448365a952469c506c00b5fe93
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISL2 ISL1 SCN7A LRP1 LTBP2

6.30e-0519297584149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 ADAMTSL3 PTGFRN SCN7A LRP1

6.46e-05193975ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 ADAMTSL3 PTGFRN SCN7A LRP1

6.46e-0519397522c58032e58730715224d7934968ce92d150b0e8
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FLNA ADAMTSL3 CRIP2 NDST3 LTBP2

6.46e-05193975000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellLA|World / Chamber and Cluster_Paper

LRP1B GLI2 LRP1 LRP2 LTBP2

6.46e-05193975d4bf89437216baf489ea0239136dcedf3b6714af
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 ADAMTSL3 PTGFRN SCN7A LRP1

6.46e-05193975573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 ISL2 ADAMTSL3 SCN7A LRP1

6.61e-05194975e2db75f4de114631b8bda4e188f84446545538b7
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 ADAMTSL3 PTGFRN SCN7A LRP1

6.61e-05194975da926441053b499cb5107ccb116fb1b3844d82b7
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 ADAMTSL3 PTGFRN SCN7A LRP1

6.61e-0519497554a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 ADAMTSL3 PTGFRN SCN7A LRP1

6.61e-05194975f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

ADAMTSL3 SCN7A LRP1 LTBP2 EPB41L2

6.78e-05195975f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA GLI2 LRP1 LTBP2 EPB41L2

6.94e-05196975fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA GLI2 LRP1 LTBP2 EPB41L2

6.94e-05196975802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 ADAMTSL3 GLI2 SCN7A LTBP2

6.94e-051969757d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

PLA2R1 GLI2 SCN7A LTBP2 EPB41L2

7.11e-05197975f1c8936986123a3151140c374fcd62d6705c530b
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPB41L5 TRIM24 ZSCAN16 BRAT1 EPB41L2

7.11e-05197975789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FLNA ADAMTSL3 CRIP2 ITGB1BP2 LTBP2

7.28e-05198975637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 MDK ADAMTSL3 CRIP2 SCN7A

7.28e-0519897512cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WT1 THSD7B ANKRD53 DKK1 LTBP2

7.28e-051989750cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

USP53 PLA2R1 GLI2 SCN7A LTBP2

7.28e-05198975df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 ADAMTSL3 GLI2 SCN7A LTBP2

7.28e-051989758f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WT1 THSD7B ANKRD53 DKK1 LTBP2

7.28e-05198975e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP53 RGS3 TMEM47 SCN7A LTBP2

7.46e-051999757f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP53 RGS3 TMEM47 SCN7A LTBP2

7.46e-05199975301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FLNA LRP1B CRIP2 ITGB1BP2 LTBP2

7.46e-05199975a207b4891881149d4c50721310690fd794157723
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP53 RGS3 TMEM47 SCN7A LTBP2

7.46e-051999759a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

VIPR2 ADAMTSL3 NDST3 LRP1 LTBP2

7.64e-05200975a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTSL3 SCN7A LRP1 LTBP2 EPB41L2

7.64e-05200975b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell390C-Fibroblasts|390C / Donor, Lineage, Cell class and subclass (all cells)

MDK TMEM47 SCN7A LRP1 LTBP2

7.64e-052009753abe0f017fee6057ba73bd661a2bc8ec9e2bfe38
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PLA2R1 LDB1 TRPM3 GLI2 MSS51

7.64e-05200975b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

USP53 ADAMTSL3 SCN7A LRP1 LTBP2

7.64e-0520097534f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIPR2 ADAMTSL3 SCN7A LRP1 EPB41L2

7.64e-052009750c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)-|Striatum / BrainAtlas - Mouse McCarroll V32

FOLR1 ZSWIM2 ISL2 LRP2

1.25e-0411797426dec09112532f351fb7a2202bae84c365707b40
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)|Striatum / BrainAtlas - Mouse McCarroll V32

FOLR1 ZSWIM2 ISL2 LRP2

1.25e-04117974db053c874e6739052dff1f91643e51b306236237
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)--|Striatum / BrainAtlas - Mouse McCarroll V32

FOLR1 ZSWIM2 ISL2 LRP2

1.25e-0411797480780223502d18f0d86a29ff3cb74aa8235103c7
ToppCellStriatum-Macroglia-CSF_related-EPENDYMAL|Striatum / BrainAtlas - Mouse McCarroll V32

FOLR1 ZSWIM2 ISL2 LRP2

1.25e-0411797440889f4a387846abbf54469cc4faf616bfe348d0
ToppCellStriatum-Macroglia-CSF_related|Striatum / BrainAtlas - Mouse McCarroll V32

FOLR1 ZSWIM2 ISL2 LRP2

1.25e-04117974e12e37e393257db85f7f5c13454095c44f59d374
ToppCellGlobus_pallidus|World / BrainAtlas - Mouse McCarroll V32

TMEM86B ISL1 DGKK SCN5A

1.66e-0412697444b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

SCN7A LRP1 LTBP2 EPB41L2

1.82e-0412997413cd10ffdd8f1ef7721884e9efd2cf25f170f414
Diseasecystitis (is_marker_for)

MUC2 MUC5AC

9.20e-062902DOID:1679 (is_marker_for)
DiseaseOsteosarcoma

RB1 FOLR1 WT1 TOPORS

1.31e-0547904C0029463
Diseasesputum mucin-5B amount

MUC2 MUC5AC

2.75e-053902OBA_2050332
DiseaseHyaloideoretinal degeneration of Wagner

COL2A1 WT1

5.50e-054902C1840452
DiseaseMalignant Cystosarcoma Phyllodes

FLNA KMT2D

9.15e-055902C0600066
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC5AC

9.15e-055902DOID:3030 (is_marker_for)
DiseasePhyllodes Tumor

FLNA KMT2D

9.15e-055902C0010701
Diseaseepilepsy (implicated_via_orthology)

LRP1B PRICKLE3 SCN5A SCN7A LRP1

1.46e-04163905DOID:1826 (implicated_via_orthology)
Diseaseresponse to radiation, prostate carcinoma, erectile dysfunction

LRP1B PTGFRN GLI2

1.98e-0437903EFO_0001663, EFO_0004234, GO_0009314
DiseaseDickkopf-related protein 4 measurement

APOH DKK1

2.55e-048902EFO_0008110
DiseaseColorectal Carcinoma

CD46 ZNF232 ADAMTSL3 NDST3 LDB1 P2RX7 LRP1 LRP2 ZSCAN16

2.95e-04702909C0009402
DiseaseProstatic Cancer, Castration-Resistant

CD46 TRIM24

3.27e-049902C3658266
DiseaseProstatic Neoplasms, Castration-Resistant

CD46 TRIM24

3.27e-049902C3658267
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

MUC2 MUC5AC

3.27e-049902EFO_0009824
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN5A SCN7A

4.07e-0410902DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN5A SCN7A

4.07e-0410902DOID:0080422 (implicated_via_orthology)
Diseaseadult onset asthma

ADAMTSL3 LRP1 MUC2 MUC5AC

4.76e-04118904EFO_1002011
DiseaseSensory hearing loss

COL2A1 LRP2

4.97e-0411902C1691779
Diseaseeosinophil count

FLNA ZFPM1 APOH PTGFRN PLA2R1 MED12L LTBP2 ZC3H7B MUC2 MUC5AC ZRANB1 SLC35A5 RBX1

5.69e-0414889013EFO_0004842
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

WT1 LRP1

5.95e-0412902DOID:3827 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN5A SCN7A

5.95e-0412902DOID:0060170 (implicated_via_orthology)
Diseasedickkopf‐related protein 1 measurement

ZFPM1 DKK1

5.95e-0412902EFO_0010620
Disease3-hydroxypropylmercapturic acid measurement

THSD7B LRP1B USP31 TRPM3 MED12L ADAMTS20

7.41e-04352906EFO_0007014
Diseaseurolithiasis

DGKD ZFPM1 EPB41L2

9.55e-0463903MONDO_0024647
DiseaseJT interval

DGKD ZFPM1 SCN5A LTBP2 KDM1B

9.90e-04248905EFO_0007885
DiseaseSpondyloepiphyseal Dysplasia

COL2A1 FLNA

1.07e-0316902C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

COL2A1 FLNA

1.07e-0316902C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

COL2A1 FLNA

1.07e-0316902C4551479
DiseaseSchwartz-Jampel Syndrome

COL2A1 FLNA

1.07e-0316902C0036391
DiseaseMelnick-Needles Syndrome

COL2A1 FLNA

1.07e-0316902C0025237
Diseasesphingomyelin 14:0 measurement

CHORDC1 TRPM3

1.21e-0317902EFO_0010390
DiseaseVan Buchem disease

COL2A1 FLNA

1.21e-0317902C0432272
Diseaseosteochondrodysplasia (is_implicated_in)

COL2A1 FLNA

1.52e-0319902DOID:2256 (is_implicated_in)
DiseaseOsteochondrodysplasias

COL2A1 FLNA

1.52e-0319902C0029422
DiseaseDyschondroplasias

COL2A1 FLNA

1.52e-0319902C0013366
DiseaseMultiple Epiphyseal Dysplasia

COL2A1 FLNA

1.69e-0320902C0026760
DiseaseSensorineural Hearing Loss (disorder)

COL2A1 LRP2

2.23e-0323902C0018784
Diseaseinflammatory bowel disease (implicated_via_orthology)

MUC2 EPB41L2

2.64e-0325902DOID:0050589 (implicated_via_orthology)
Diseasehair colour measurement

ZFPM1 RGS3 KMT2D MED12L LRP1 EPB41L2 RBX1

2.78e-03615907EFO_0007822

Protein segments in the cluster

PeptideGeneStartEntry
QKRLCHPCWEVRDSA

BRAT1

506

Q6PJG6
HGNWTKLPECREVKC

APOH

191

P02749
TGEKTRPWSCRCKHE

ARMCX4

2021

Q5H9R4
HKACRSVRCPSWKAN

ADAMTS20

1466

P59510
RTCRDLKLCHPEWKS

COL2A1

1281

P02458
PCDDKRHRDIWSKEK

NDST3

576

O95803
FHCISRWLKTRQVCP

RBX1

81

P62877
CQKLKIPDHVRERAW

RB1

61

P06400
RPHICSFWVKGECKR

RBM22

161

Q9NW64
LEAHSQEQKKRVCWC

RGS3

646

P49796
EPCNDHVRAKLSWAK

HAGHL

186

Q6PII5
KPIDFCKIWNHRACA

ANKRD53

246

Q8N9V6
HRLCALRASKDCKWN

DGKK

366

Q5KSL6
QFRCKNKAHCIPIRW

LRP1B

3636

Q9NZR2
CEWAVSCKRSGKHRA

MED12L

511

Q86YW9
WSRAAPECKVVKCRF

CD46

216

P15529
PRDCLKTCLFQKWQR

LDB1

266

Q86U70
PIFHDALKGWSCCRK

ITGB1BP2

31

Q9UKP3
ECQKSDWPAHRRVCQ

MSS51

136

Q4VC12
QRIRCRVPCNWKKEF

MDK

66

P21741
KSGHCIPLRWRCDAD

LRP1

3621

Q07954
RTVWLGCPEKCEEKH

ATP9B

116

O43861
PNHRAAKRLWKVCVE

EPB41L2

476

O43491
PHRRSWAEKQCSILK

MUC2

1041

Q02817
KIPACVHRSWDCRIS

FAM205A

691

Q6ZU69
KIPACVHRSWDCRIS

FAM205BP

421

Q63HN1
FDPKAWRAQCRCKHS

FAM221B

321

A6H8Z2
HRKDDALWCRVTKPV

ZFPM1

166

Q8IX07
VCRWQACTREQKPFK

GLI2

471

P10070
PAHWRCDKRNDCVDG

LRP2

1081

P98164
QPVTRDCHLRCTWTK

MUC5AC

3216

P98088
GWRKICQHCKCPREE

PRICKLE3

41

O43900
SCCRWRIRKEFPKSE

P2RX7

571

Q99572
QCVAAKPESWQRDCH

CHCHD5

21

Q9BSY4
FRLDHPKACKHLWKC

EPB41L5

301

Q9HCM4
QCTKPECRKWRQLTK

KDM1B

141

Q8NB78
WRICLAHEFTEKRKP

GBA2

86

Q9HCG7
RWCNEHLKCVSKRIA

FLNA

51

P21333
KDCRCHSRLFPRTWD

IFNL2

71

Q8IZJ0
CLHWRLSKRKCETNN

CHIC2

131

Q9UKJ5
RRQDKLWFCCLSPNH

ELMO3

556

Q96BJ8
CWKKVTNDVCSEPLR

LTBP2

1586

Q14767
DLKKCLRTHAPCWGT

GPR173

346

Q9NS66
KCTHQPCLIKWISER

MARCHF4

186

Q9P2E8
AHKRCAVRATNNCKW

DGKD

201

Q16760
DTEFRKHCCEWIKRI

HAUS6

86

Q7Z4H7
KEWCFKPCEIRELSH

GDA

56

Q9Y2T3
SLGKDWHRPCLRCER

CRIP2

141

P52943
CARHFWSKICKPVLK

DKK1

201

O94907
DKLHEQCRPWRKNAC

FOLR1

51

P15328
RVSPDLEWHAACLKC

ISL2

41

Q96A47
CWPSSRTLFCREQKH

RNF186

206

Q9NXI6
HWCCKKEVQETRRER

PTGFRN

856

Q9P2B2
WEHKEKCCARCQQVL

SYTL3

56

Q4VX76
CWEKECPVKRERLSE

TRMT1

501

Q9NXH9
HAKCVDKWLKANRTC

RNF38

486

Q9H0F5
DKWLKANRTCPICRA

RNF38

491

Q9H0F5
RWLARQKTCPCCRKE

RNF151

46

Q2KHN1
LCSPRNKQRCARLWK

TEDDM1

11

Q5T9Z0
LEESRHKCPPCWNRL

SCN5A

676

Q14524
RKPRVQCLKCHLWQH

SHPRH

671

Q149N8
RVSPDLEWHAACLKC

ISL1

31

P61371
LHCGSKREWICKIPR

PLA2R1

786

Q13018
EIKDNCRNWKPTCDV

SIX6OS1

71

Q8N1H7
CRNWKPTCDVFRKHE

SIX6OS1

76

Q8N1H7
IQVRNVRCIKCHKWG

CIR1

121

Q86X95
PVFHDALKGWSCCKR

CHORDC1

31

Q9UHD1
GTRWKDVVSKCIRCH

USP53

326

Q70EK8
KVICWLCERSQEHRG

TRIM5

111

Q9C035
EWCRALICRHEKPSA

TGFA

131

P01135
EWLCKTCIRAHQRVK

TRIM24

181

O15164
ELCCQWLRPEVHSKE

ZSCAN30

71

Q86W11
LCCQWLRPKTHSKEE

ZSCAN32

61

Q9NX65
RSECPRKDNCTAKEW

SLC35A5

196

Q9BS91
KCIDKWSDRHRNCPI

RNF141

176

Q8WVD5
LCCRWRKHESDPDER

TRPM3

1186

Q9HCF6
TREKPHACKWCERRF

ZBTB18

461

Q99592
LRKPARSKHCSVCNW

ZDHHC4

156

Q9NPG8
CRWPSCQKKFARSDE

WT1

416

P19544
ESCRKPASLDIWHCE

TMEM47

56

Q9BQJ4
KTHCSAQRPDVCRWL

TMEM86B

11

Q8N661
AKEDWCAKCQLVRPA

ZDHHC23

256

Q8IYP9
EVQCELKRKWRSRCP

VIPR2

381

P41587
PCTHKFHRKCIDNWL

ZSWIM2

361

Q8NEG5
IPHGEREFWELCNKC

ZDHHC21

81

Q8IVQ6
REKPHACRWCERRFT

ZBTB42

386

B2RXF5
CRQWLRPECHTKEQI

ZSCAN16

66

Q9H4T2
RCVQEWSKNKAECPL

TOPORS

126

Q9NS56
RELCCQWLKPEIHTK

ZNF165

71

P49910
QRVHTGEKPWKCSEC

ZNF26

501

P17031
LCCEWLRPEKHTKEQ

ZNF232

76

Q9UNY5
NCSPCWLKLKEFVHR

SCN7A

486

Q01118
LAPDDAWRCPHCKQL

USP31

611

Q70CQ4
EWNVERNKVKALHCC

WDR12

171

Q9GZL7
RVKWRPECRHHLATC

WDR24

256

Q96S15
RPPKERSCFRVCDWH

THSD7B

86

Q9C0I4
ENWAKAKRCVVCDHP

ZRANB1

161

Q9UGI0
KKLHQCEDCEKIFRW

ZNF7

631

P17097
WRIHSKEKPFVCQEC

ZNF337

676

Q9Y3M9
CSAKARHCWTKERRV

ZC3H7B

716

Q9UGR2
RHCVQKKKPISWRHC

ADAMTSL3

1636

P82987
TARKRAGWQCPECKV

KMT2D

261

O14686