Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

HSPG2 CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2 PPEF2 PLA2G4D SYT10 RYR1 RYR2 RYR3 ITPR2 SLC8A1 CDK5R1 HMCN2 ANKEF1 LRP2 EDEM1 PLS3

1.22e-0774918524GO:0005509
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RASA3 RYR1 RYR2 RYR3 ITPR2

5.02e-07181855GO:0015278
GeneOntologyMolecularFunctioncoumarin 7-hydroxylase activity

CYP2A6 CYP2A7 CYP2A13

7.83e-0731853GO:0008389
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2 RYR3

3.11e-0641853GO:0005219
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RASA3 RYR1 RYR2 RYR3 ITPR2

9.04e-06311855GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RASA3 RYR1 RYR2 RYR3 ITPR2

1.24e-05331855GO:0005217
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2 RYR3

1.53e-0561853GO:0048763
GeneOntologyMolecularFunctionX11-like protein binding

CLSTN3 CLSTN2

2.55e-0431852GO:0042988
GeneOntologyMolecularFunctioncalmodulin binding

MYO1G MYO1D RYR1 RYR2 RYR3 SLC8A1 MYO15A SNTA1 SNTB2

3.04e-042301859GO:0005516
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO1G MYO1D MYO19 MYO15A

4.12e-04381854GO:0000146
GeneOntologyMolecularFunctionDNA endonuclease activity

APEX1 XRCC3 FAN1 N4BP2

7.25e-04441854GO:0004520
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1G DNHD1 MYO1D MYO19 DNAH14 MYO15A

8.15e-041181856GO:0003774
GeneOntologyMolecularFunctionphosphodiesterase I activity

APEX1 FAN1

8.38e-0451852GO:0004528
GeneOntologyBiologicalProcesscellular response to caffeine

RYR1 RYR2 RYR3 SLC8A1

1.97e-06111854GO:0071313
GeneOntologyBiologicalProcesscellular response to purine-containing compound

RYR1 RYR2 RYR3 SLC8A1

5.85e-06141854GO:0071415
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2 HMCN2

7.57e-0618718510GO:0007156
GeneOntologyBiologicalProcessintracellular transport

SMG1 CLTCL1 HDAC6 IPO8 IPO7 ACD MYO1D COPA UACA ZFYVE16 VPS13C MYO19 VTA1 BLOC1S1 COG3 ANKRD50 DTNBP1 ASB15 TRAK1 FBXO22 MDN1 PPP6C IER3IP1 TBC1D14 VPS13A LRP2 HERC2 EDEM1 CLEC16A GOLGA2 VPS13B

1.01e-05149618531GO:0046907
GeneOntologyBiologicalProcessneuron projection morphogenesis

BOC HSPG2 CLSTN3 ATP7A HDAC6 ACHE LAMA1 CDKL3 PCDHAC2 CLASP2 CUL7 DTNBP1 TRAK1 CDK5R1 HMCN2 PTPRD PTPRS VPS13A LRP2 POTEJ GOLGA2

1.12e-0580218521GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

BOC HSPG2 CLSTN3 ATP7A HDAC6 ACHE LAMA1 CDKL3 PCDHAC2 CLASP2 CUL7 DTNBP1 TRAK1 CDK5R1 HMCN2 PTPRD PTPRS VPS13A LRP2 POTEJ GOLGA2

1.54e-0581918521GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

BOC HSPG2 CLSTN3 ATP7A HDAC6 ACHE LAMA1 CDKL3 PCDHAC2 CLASP2 CUL7 DTNBP1 TRAK1 CDK5R1 HMCN2 PTPRD PTPRS VPS13A LRP2 POTEJ GOLGA2

1.74e-0582618521GO:0048858
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2 HMCN2 PTPRD PTPRS

2.72e-0531318512GO:0098742
GeneOntologyBiologicalProcessresponse to caffeine

RYR1 RYR2 RYR3 SLC8A1

3.33e-05211854GO:0031000
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

BOC HSPG2 ATP7A HDAC6 ACHE LAMA1 CDKL3 PCDHAC2 CLASP2 CUL7 DTNBP1 TRAK1 CDK5R1 HMCN2 PTPRD PTPRS LRP2 POTEJ GOLGA2

4.54e-0574818519GO:0048667
GeneOntologyBiologicalProcessactin filament-based process

MYO1G HDAC6 MYO1D EPB41L4B MYO19 CARMIL1 CLASP2 DTNBP1 NPHP4 RYR2 KPTN CDK5R1 KASH5 DLG1 MAD2L2 POTEJ IKBKB MYO15A NLRP4 PLS3 SNTA1

7.32e-0591218521GO:0030029
GeneOntologyBiologicalProcessdendrite morphogenesis

ATP7A HDAC6 ACHE CDKL3 CUL7 DTNBP1 TRAK1 CDK5R1 PTPRD

7.75e-051981859GO:0048813
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

CYP2A6 CYP2A7 CYP2A13

8.13e-05101853GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

CYP2A6 CYP2A7 CYP2A13

8.13e-05101853GO:0009804
GeneOntologyBiologicalProcessneuron projection development

BOC HSPG2 CLSTN3 ATP7A HDAC6 ACHE LAMA1 CDKL3 PCDHAC2 CLASP2 BLOC1S1 CUL7 DTNBP1 TRAK1 CDK5R1 HMCN2 PTPRD PTPRS VPS13A FBXO7 LRP2 LTK POTEJ IKBKB GOLGA2 VPS13B

8.45e-05128518526GO:0031175
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

LEMD3 LAMA1 CLASP2 CHADL IER3IP1 MAD2L2

1.09e-04841856GO:1903053
GeneOntologyBiologicalProcessactin cytoskeleton organization

MYO1G HDAC6 MYO1D EPB41L4B MYO19 CARMIL1 CLASP2 DTNBP1 NPHP4 KPTN CDK5R1 KASH5 DLG1 MAD2L2 POTEJ IKBKB MYO15A NLRP4 PLS3

1.16e-0480318519GO:0030036
GeneOntologyBiologicalProcessendosomal transport

CLTCL1 MYO1D ZFYVE16 VTA1 BLOC1S1 ANKRD50 ASB15 TBC1D14 LRP2 CLEC16A VPS13B

1.55e-0432018511GO:0016197
GeneOntologyBiologicalProcessaxonogenesis

BOC HSPG2 HDAC6 ACHE LAMA1 CDKL3 PCDHAC2 CLASP2 TRAK1 CDK5R1 HMCN2 PTPRS LRP2 POTEJ GOLGA2

1.87e-0456618515GO:0007409
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

CLSTN3 ATP7A HDAC6 ACD ACHE CARMIL1 CDKL3 CLASP2 CLSTN2 CUL7 DTNBP1 NPHP4 TRAK1 CDK5R1 NCAPG PTPRD IER3IP1 FBXO7 LRP2 DLG1 LTK SHCBP1L MAD2L2 IKBKB CLEC16A GOLGA2

2.24e-04136618526GO:0051130
GeneOntologyBiologicalProcessneuron development

BOC HSPG2 CLSTN3 ATP7A HDAC6 ACHE LAMA1 CDKL3 PCDHAC2 CLASP2 BLOC1S1 CUL7 DTNBP1 NPHP4 TRAK1 CDK5R1 HMCN2 PTPRD PTPRS VPS13A FBXO7 LRP2 LTK POTEJ IKBKB GOLGA2 VPS13B

2.75e-04146318527GO:0048666
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

RYR1 RYR2 RYR3 SLC8A1

3.28e-04371854GO:0014808
GeneOntologyBiologicalProcesspositive regulation of dendrite morphogenesis

HDAC6 ACHE CDKL3 CUL7 PTPRD

3.39e-04671855GO:0050775
GeneOntologyCellularComponentaxon

BOC ATP7A HDAC6 MYO1D COPA ACHE CLASP2 BLOC1S1 DTNBP1 TRAK1 ITPR2 SLC8A1 CDK5R1 HMCN2 PTPRS LRP2 DLG1 CTNND1 POTEJ CD200

1.03e-0489118220GO:0030424
GeneOntologyCellularComponentgrowth cone

BOC COPA CLASP2 DTNBP1 TRAK1 CDK5R1 PTPRS LRP2 CTNND1

3.07e-042451829GO:0030426
GeneOntologyCellularComponentsite of polarized growth

BOC COPA CLASP2 DTNBP1 TRAK1 CDK5R1 PTPRS LRP2 CTNND1

3.88e-042531829GO:0030427
GeneOntologyCellularComponentcell cortex

CNKSR1 MYO1D CLASP2 RYR1 TRAK1 ITPR2 SEPTIN3 HMCN2 INSC CTNND1 NLRP4

4.25e-0437118211GO:0005938
GeneOntologyCellularComponentsomatodendritic compartment

BOC CLSTN3 ATP7A HDAC6 MYO1D COPA ACHE RGS11 CNKSR2 CLSTN2 DTNBP1 TRAK1 SLC8A1 CDK5R1 HMCN2 PTPRS VPS13A LRP2 DLG1 CTNND1 GOLGA2 CD200 PDE11A

4.36e-04122818223GO:0036477
GeneOntologyCellularComponentsarcoplasm

XDH DTNBP1 RYR1 RYR2 RYR3 ITPR2

4.92e-041141826GO:0016528
GeneOntologyCellularComponentaxonal growth cone

BOC CLASP2 TRAK1 LRP2

6.27e-04451824GO:0044295
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 RYR2 RYR3 ITPR2

6.27e-04451824GO:0033017
GeneOntologyCellularComponentsmooth endoplasmic reticulum

MYO1D RYR1 RYR2 RYR3

6.82e-04461824GO:0005790
GeneOntologyCellularComponentcytoplasmic side of membrane

RASA3 BLOC1S1 RYR1 RYR2 RYR3 THADA DLG1 IKBKB

9.44e-042301828GO:0098562
GeneOntologyCellularComponentneuronal cell body

BOC ATP7A HDAC6 MYO1D COPA ACHE CNKSR2 DTNBP1 SLC8A1 CDK5R1 HMCN2 PTPRS VPS13A DLG1 GOLGA2 CD200 PDE11A

1.03e-0383518217GO:0043025
GeneOntologyCellularComponentsarcoplasmic reticulum

XDH RYR1 RYR2 RYR3 ITPR2

1.03e-03881825GO:0016529
GeneOntologyCellularComponentprotein phosphatase 4 complex

PPP4R3A PPP4C

1.11e-0361822GO:0030289
GeneOntologyCellularComponentsarcolemma

DTNBP1 RYR1 RYR2 RYR3 SLC8A1 DLG1 SNTA1

1.41e-031901827GO:0042383
Domain-

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C PPP1R27

6.32e-10248189171.25.40.20
DomainANK

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C PPP1R27

7.60e-1025118917SM00248
DomainANK_REPEAT

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C PPP1R27

8.58e-1025318917PS50088
DomainAnkyrin_rpt-contain_dom

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C PPP1R27

9.12e-1025418917IPR020683
DomainANK_REP_REGION

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C PPP1R27

9.12e-1025418917PS50297
DomainAnk

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ ANKRD20A1 PPP1R12C PPP1R27

1.46e-0922818916PF00023
DomainAnkyrin_rpt

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C PPP1R27

1.46e-0926218917IPR002110
DomainAnk_2

ANKK1 UACA ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C

5.27e-0921518915PF12796
DomainARM-type_fold

SMG1 CLTCL1 IPO8 IPO7 MIF4GD CLASP2 CUL7 RYR3 PPP4R3A ITPR2 ARFGEF3 THADA NCAPG PIK3C2B INSC UTP20 CTNND1 EIF3M

1.12e-0833918918IPR016024
DomainRIH_assoc-dom

RYR1 RYR2 RYR3 ITPR2

1.50e-0761894IPR013662
DomainIns145_P3_rec

RYR1 RYR2 RYR3 ITPR2

1.50e-0761894PF08709
DomainRIH_assoc

RYR1 RYR2 RYR3 ITPR2

1.50e-0761894PF08454
DomainRIH_dom

RYR1 RYR2 RYR3 ITPR2

1.50e-0761894IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2 RYR3 ITPR2

1.50e-0761894IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2 RYR3 ITPR2

1.50e-0761894IPR015925
Domain-

RYR1 RYR2 RYR3 ITPR2

1.50e-07618941.25.10.30
DomainRYDR_ITPR

RYR1 RYR2 RYR3 ITPR2

1.50e-0761894PF01365
DomainCRIC

CNKSR1 CNKSR2 CNKSR3

1.02e-0631893PS51290
DomainRyanodine_rcpt

RYR1 RYR2 RYR3

1.02e-0631893IPR003032
DomainCRIC_domain

CNKSR1 CNKSR2 CNKSR3

1.02e-0631893IPR017874
DomainCRIC_ras_sig

CNKSR1 CNKSR2 CNKSR3

1.02e-0631893PF10534
DomainRyanrecept_TM4-6

RYR1 RYR2 RYR3

1.02e-0631893IPR009460
DomainRyR

RYR1 RYR2 RYR3

1.02e-0631893PF02026
DomainRR_TM4-6

RYR1 RYR2 RYR3

1.02e-0631893PF06459
DomainRyan_recept

RYR1 RYR2 RYR3

1.02e-0631893IPR013333
DomainCadherin_tail

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

1.78e-06371896PF15974
DomainCadherin_CBD

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

1.78e-06371896IPR031904
DomainMIR

RYR1 RYR2 RYR3 ITPR2

2.03e-06101894PF02815
DomainMIR_motif

RYR1 RYR2 RYR3 ITPR2

2.03e-06101894IPR016093
DomainMIR

RYR1 RYR2 RYR3 ITPR2

2.03e-06101894PS50919
DomainMIR

RYR1 RYR2 RYR3 ITPR2

2.03e-06101894SM00472
DomainCADHERIN_1

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2

2.22e-061131899PS00232
DomainCadherin

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2

2.22e-061131899PF00028
DomainCADHERIN_2

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2

2.39e-061141899PS50268
Domain-

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2

2.39e-0611418992.60.40.60
DomainCA

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2

2.57e-061151899SM00112
DomainCadherin-like

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2

2.76e-061161899IPR015919
DomainCadherin

CLSTN3 CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CLSTN2

3.18e-061181899IPR002126
DomainCyt_P450_E_grp-I_CYP2A-like

CYP2A6 CYP2A7 CYP2A13

4.05e-0641893IPR008067
DomainSHR-BD

VPS13C VPS13A VPS13B

4.05e-0641893IPR009543
DomainVPS13_C

VPS13C VPS13A VPS13B

4.05e-0641893PF16909
DomainVPS13_C

VPS13C VPS13A VPS13B

4.05e-0641893IPR031645
DomainSHR-BD

VPS13C VPS13A VPS13B

4.05e-0641893PF06650
DomainAutophagy-rel_C

VPS13C VPS13A VPS13B

1.00e-0551893IPR015412
DomainATG_C

VPS13C VPS13A VPS13B

1.00e-0551893PF09333
DomainCadherin_2

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

4.99e-05651896PF08266
DomainCadherin_N

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

4.99e-05651896IPR013164
DomainChorein_N

VPS13C VPS13A VPS13B

5.50e-0581893PF12624
DomainVPS13_N

VPS13C VPS13A VPS13B

5.50e-0581893IPR026854
DomainARM-like

SMG1 IPO8 IPO7 RIPOR3 CLASP2 CUL7 PPP4R3A NCAPG INSC UTP20 CTNND1

9.96e-0527018911IPR011989
DomainCNKSR2

CNKSR2 CNKSR3

1.02e-0421892IPR010599
DomainDUF1170

CNKSR2 CNKSR3

1.02e-0421892PF06663
DomainCadherin_CS

CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

1.21e-041091897IPR020894
Domain-

CNKSR1 GIPC2 FRMPD2 CNKSR2 CNKSR3 DLG1 SNTA1 SNTB2

1.47e-0415018982.30.42.10
DomainPDZ

CNKSR1 GIPC2 FRMPD2 CNKSR2 CNKSR3 DLG1 SNTA1 SNTB2

1.54e-041511898PS50106
DomainPDZ

CNKSR1 GIPC2 FRMPD2 CNKSR2 CNKSR3 DLG1 SNTA1 SNTB2

1.61e-041521898IPR001478
DomainPP2Ac

PPEF2 PPP4C PPP6C

2.71e-04131893SM00156
DomainSer/Thr-sp_prot-phosphatase

PPEF2 PPP4C PPP6C

2.71e-04131893IPR006186
DomainSER_THR_PHOSPHATASE

PPEF2 PPP4C PPP6C

2.71e-04131893PS00125
DomainCul7

CUL7 HERC2

3.04e-0431892PF11515
DomainCalsyntenin

CLSTN3 CLSTN2

3.04e-0431892IPR026914
DomainCse1

IPO8 IPO7

3.04e-0431892PF08506
DomainCPH_domain

CUL7 HERC2

3.04e-0431892IPR021097
DomainVPS13

VPS13C VPS13A

3.04e-0431892IPR026847
DomainCse1

IPO8 IPO7

3.04e-0431892IPR013713
DomainVPS13_mid_rpt

VPS13C VPS13A

3.04e-0431892PF16910
DomainVPS13

VPS13C VPS13A

3.04e-0431892PF16908
DomainVPS13_N2

VPS13C VPS13A

3.04e-0431892IPR031646
DomainVPS13_mid_rpt

VPS13C VPS13A

3.04e-0431892IPR031642
Domain-

IPO8 IPO7 RIPOR3 CLASP2 CUL7 NCAPG INSC UTP20 CTNND1

4.44e-0422218991.25.10.10
DomainMyosin_head_motor_dom

MYO1G MYO1D MYO19 MYO15A

5.73e-04381894IPR001609
DomainMYOSIN_MOTOR

MYO1G MYO1D MYO19 MYO15A

5.73e-04381894PS51456
DomainMyosin_head

MYO1G MYO1D MYO19 MYO15A

5.73e-04381894PF00063
DomainMYSc

MYO1G MYO1D MYO19 MYO15A

5.73e-04381894SM00242
DomainPDZ

GIPC2 FRMPD2 CNKSR2 CNKSR3 DLG1 SNTA1 SNTB2

5.87e-041411897PF00595
DomainPDZ

GIPC2 FRMPD2 CNKSR2 CNKSR3 DLG1 SNTA1 SNTB2

7.83e-041481897SM00228
DomainCadherin_C

PCDHA9 PCDHGB2 PCDHAC2 PCDHA7

8.42e-04421894IPR032455
DomainCadherin_C_2

PCDHA9 PCDHGB2 PCDHAC2 PCDHA7

8.42e-04421894PF16492
Domain2Fe2S_fd_BS

RNF186 XDH

9.98e-0451892IPR006058
DomainSyntrophin

SNTA1 SNTB2

9.98e-0451892IPR015482
Domain2FE2S_FER_1

RNF186 XDH

9.98e-0451892PS00197
DomainIQ

MYO1D MYO19 PPEF2 LRRIQ1 MYO15A

1.38e-03811895SM00015
DomainConA-like_dom

HSPG2 CLSTN3 LAMA1 CLSTN2 RYR1 RYR2 RYR3 COL24A1

1.78e-032191898IPR013320
DomainAPC_su10/DOC_dom

CUL7 HERC2

2.07e-0371892IPR004939
DomainDOC

CUL7 HERC2

2.07e-0371892PS51284
DomainANAPC10

CUL7 HERC2

2.07e-0371892PF03256
DomainMyosin_TH1

MYO1G MYO1D

2.07e-0371892PF06017
DomainMyosin_TH1

MYO1G MYO1D

2.07e-0371892IPR010926
DomainTH1

MYO1G MYO1D

2.07e-0371892PS51757
DomainAPC10

CUL7 HERC2

2.07e-0371892SM01337
DomainIQ_motif_EF-hand-BS

MYO1D MYO19 PPEF2 LRRIQ1 MYO15A

2.21e-03901895IPR000048
DomainLRR_6

NLRP11 CARMIL1 FBXL20 NLRP4

2.32e-03551894PF13516
DomainIQ

MYO1D MYO19 PPEF2 LRRIQ1 MYO15A

2.55e-03931895PS50096
DomainLAMININ_IVA

HSPG2 LAMA1

2.74e-0381892PS51115
DomainLaminin_B

HSPG2 LAMA1

2.74e-0381892PF00052
DomainLamB

HSPG2 LAMA1

2.74e-0381892SM00281
DomainLaminin_IV

HSPG2 LAMA1

2.74e-0381892IPR000034
DomainMetallophos

PPEF2 PPP4C PPP6C

2.77e-03281893PF00149
DomainCalcineurin-like_PHP_ApaH

PPEF2 PPP4C PPP6C

2.77e-03281893IPR004843
Domain-

HSPG2 CLSTN3 LAMA1 CLSTN2 COL24A1

2.80e-039518952.60.120.200
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR1 RYR2 RYR3 ITPR2

1.75e-05191204M47760
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2 RYR3 ITPR2 SLC8A1

9.32e-05541205M27460
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2 RYR3 ITPR2 SLC8A1

9.32e-05541205MM15202
PathwayREACTOME_CYP2E1_REACTIONS

CYP2A6 CYP2A7 CYP2A13

9.44e-05111203M27130
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR1 RYR2 RYR3

9.44e-05111203M47958
PathwayREACTOME_CYP2E1_REACTIONS

CYP2A6 CYP2A7 CYP2A13

1.25e-04121203MM14847
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR1 RYR2 RYR3

1.62e-04131203M39589
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

IPO7 MYO1D COPA ZFYVE16 LEMD3 RNF213 CLASP2 CUL7 PPEF2 DTNBP1 PPP4R3A FAN1 ITPR2 GLMN NCAPG PPP4C PTPRD PPP6C SBF1 PTPRS VPS13A UBR3 DLG1 ANKRD28 HERC2 CTNND1 SNTB2 PPP1R12C

5.21e-1210491912827880917
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

SMG1 COG2 CLTCL1 IPO8 IPO7 COPA UACA HDHD5 MYO19 FARSB RNF213 COG3 RFC4 ITPR2 ARFGEF3 GLMN THADA NCAPG PPP4C MDN1 PPP6C EIF2B3 GEMIN4 ANKRD28 TRMT1L IKBKB SNRNP200 PLS3 EIF3M TMEM255A

3.56e-1014401913030833792
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

3.14e-0924191624698270
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR2 RYR3 ITPR2

1.31e-086191423463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR2 RYR3 ITPR2

1.31e-086191425966694
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR2 RYR3 ITPR2

1.31e-086191420519450
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR2 RYR3 ITPR2

1.31e-086191416844763
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA9 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

1.36e-0815191515640798
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA9 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

2.78e-0817191529911975
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR2 RYR3 ITPR2

3.05e-087191411860456
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA9 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

3.83e-0818191515570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA9 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

3.83e-0818191510662547
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR2 RYR3 ITPR2

6.06e-088191419033399
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

IPO8 IPO7 ZFYVE16 LEMD3 MCC FARSB ANKRD50 PPP4R3A FBXO22 PTPRD SBF1 PTPRS EIF2B3 GEMIN4 DLG1 ANKRD28 EDEM1 SNRNP200 PLS3 SNTA1 SNTB2

1.11e-079741912128675297
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

COG2 ATP7A ZFYVE16 LEMD3 VPS13C BLOC1S1 COG3 ANKRD50 ITPR2 ARFGEF3 VPS13A LRP2 CTNND1 GOLGA2 VPS13B

1.47e-075041911534432599
Pubmed

Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.

CYP2A6 CYP2A7 CYP2A13

1.63e-073191331645370
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2 RYR3

1.63e-073191318403125
Pubmed

A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319138297477
Pubmed

Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319138188299
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2 RYR3

1.63e-07319137876312
Pubmed

Comparison of hamster and mouse reveals interspecies differences in the regulation of hepatic CYP2A isozymes.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319138250953
Pubmed

The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319132703500
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2 RYR3

1.63e-073191322948152
Pubmed

Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: steroid-binding site and orientation.

CYP2A6 CYP2A7 CYP2A13

1.63e-073191322217847
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2 RYR3

1.63e-073191310788707
Pubmed

Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract.

CYP2A6 CYP2A7 CYP2A13

1.63e-073191322890016
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2 RYR3

1.63e-07319137621815
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2 RYR3

1.63e-073191310473538
Pubmed

Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319133346244
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR2 RYR3

1.63e-073191318434746
Pubmed

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319132733794
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR2 RYR3

1.63e-07319139204703
Pubmed

Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319138484736
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR2 RYR3

1.63e-073191321881589
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR2 RYR3

1.63e-073191312213830
Pubmed

Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319131417950
Pubmed

Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.

CYP2A6 CYP2A7 CYP2A13

1.63e-073191324045421
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR2 RYR3

1.63e-07319139242641
Pubmed

Highly homologous mouse Cyp2a4 and Cyp2a5 genes are differentially expressed in the liver and both express long non-coding antisense RNAs.

CYP2A6 CYP2A7 CYP2A13

1.63e-073191332987105
Pubmed

Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319132765478
Pubmed

Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation.

CYP2A6 CYP2A7 CYP2A13

1.63e-07319132415518
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR2 RYR3

1.63e-073191325239916
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR2 RYR3

1.63e-073191318643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR2 RYR3

1.63e-073191311159936
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR2 RYR3

1.63e-07319137959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR2 RYR3

1.63e-07319134600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR2 RYR3

1.63e-07319137635066
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

MYO1D COPA EPB41L4B LAMA1 CUL7 ARFGEF3 PTPRS GEMIN4 HERC2 CTNND1 SNRNP200 SNTB2

1.89e-073131911238270169
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

CDH26 PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

2.35e-0777191710835267
Pubmed

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PCDHA9 PCDHA13 PCDHA10 PCDHA7

2.82e-071119149655502
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA9 PCDHGB2 PCDHA13 PCDHA10 PCDHA7

4.20e-0728191515347688
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR1 RYR2 RYR3 SLC8A1

4.22e-0712191419095005
Pubmed

Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP.

CYP2A6 CYP2A7 CYP2A13

6.50e-074191310490589
Pubmed

Two steroid 15 alpha-hydroxylase genes and a homologous gene family in mice.

CYP2A6 CYP2A7 CYP2A13

6.50e-07419131970547
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR2 RYR3

6.50e-074191323413940
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR2 RYR3

6.50e-07419139607712
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

RYR1 RYR2 ITPR2

6.50e-074191319120137
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR1 RYR2 RYR3

6.50e-074191323482488
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR1 RYR2 RYR3

6.50e-074191318206662
Pubmed

Transcriptional regulation by HNF-4 of the steroid 15alpha-hydroxylase P450 (Cyp2a-4) gene in mouse liver.

CYP2A6 CYP2A7 CYP2A13

6.50e-07419139408084
Pubmed

Analysis of the human VPS13 gene family.

VPS13C VPS13A VPS13B

6.50e-074191315498460
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR1 RYR2 RYR3

6.50e-07419139384575
Pubmed

A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.

CYP2A6 CYP2A7 CYP2A13

6.50e-07419137565685
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

7.29e-0757191632633719
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

EPB41L4B ZNF618 VPS13C MYO19 LAMA1 RNF213 ANKRD20A3P DNAH14 RYR1 ITPR2 MDN1 TBC1D14 VPS13A LRP2 UTP20 ATIC SNRNP200

7.55e-077361911729676528
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

8.09e-0758191630377227
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 CLTCL1 RASA3 CLASP2 MED13L NPHP4 RYR1 TRAK1 ITPR2 FZD7 CDK5R1 THADA MDN1 SBF1 PIK3C2B PTPRS EIF2B3 HMGXB3 LTK HERC2 HR

8.67e-0711051912135748872
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

COG2 HDAC6 IPO8 HDHD5 TRMT112 MYO19 XRCC3 GLMN MDN1 CNKSR3 VPS13A ANKRD28 HERC2 CTNND1 CLEC16A

1.49e-066061911536538041
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ATP7A EPB41L4B LEMD3 VPS13C RNF213 CNKSR2 CLASP2 ANKRD50 RYR2 ARFGEF3 THADA VPS13A DLG1 ANKRD28 CTNND1 CLEC16A SNRNP200

1.58e-067771911735844135
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR1 RYR2 RYR3

1.62e-065191323918386
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR1 RYR2 RYR3

1.62e-065191319011160
Pubmed

Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease.

PCDHA9 PCDHA10 PCDHA7

1.62e-065191334888534
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

UACA ZNF618 MCC FARSB CNKSR2 CLASP2 MDN1 SEPTIN3 PTPRD PPP6C SBF1 PTPRS N4BP2 CNKSR3 DLG1 ANKRD28 HERC2 CTNND1 GOLGA2

1.72e-069631911928671696
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PCDHA9 ZFYVE16 MDN1 ANKRD28 HERC2 CTNND1 CLEC16A

1.83e-0610419179205841
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

RYR1 RYR2 RYR3 ITPR2 SLC8A1

2.05e-0638191530786075
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

2.09e-0668191611230163
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DNHD1 MYO1D COPA LAMA1 RNF213 RYR1 VPS13A LRP2 PLS3

2.48e-06208191933230847
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CDH26 UACA RASA3 EPB41L4B PPFIBP2 VPS13C CARMIL1 FRMPD2 RNF213 WDR27 CLASP2 COG3 DNAH14 ARFGEF3 EXD3 THADA PPP4C PTPRS TBC1D14 DLG1 CTNND1 CLEC16A EIF3M VPS13B

2.48e-0614891912428611215
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

SMG1 CLTCL1 IPO8 POLM CARMIL1 GDAP1 RNF213 RYR1 ARFGEF3 EIF2B3 VPS13A FBXO7 HERC2 EIF3M

2.55e-065521911410737800
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

2.93e-0672191610380929
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR1 RYR2 RYR3

3.22e-066191319549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR1 RYR2 RYR3

3.22e-066191326025922
Pubmed

A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.

CYP2A6 CYP2A7 CYP2A13

3.22e-06619137668294
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR1 RYR2 RYR3

3.22e-066191314592808
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR1 RYR2 RYR3

3.22e-066191319009018
Pubmed

Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19.

CYP2A6 CYP2A7 CYP2A13

3.22e-06619138587134
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

3.44e-0674191610817752
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UACA ZNF618 ANKRD62 RNF213 CUL7 ANKRD6 NPHP4 PPP4R3A FAN1 THADA N4BP2 UBR3 SNRNP200

3.86e-064931911315368895
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

CLTCL1 IPO8 IPO7 UACA RASA3 MCC PPP4R3A PPP4C PPP6C GEMIN4 ANKRD28 SNRNP200 SNTB2 PPP1R12C

3.91e-065731911428330616
Pubmed

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

RNF213 ATIC HERC2 GOLGA2

4.90e-0621191437422473
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

5.44e-0680191610716726
Pubmed

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.

CYP2A6 CYP2A7 CYP2A13

5.61e-06719139630227
Pubmed

Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules.

DLG1 SNTA1 SNTB2

5.61e-067191326617989
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR1 RYR2 RYR3

5.61e-067191320962236
Pubmed

Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster.

CYP2A6 CYP2A7 CYP2A13

5.61e-067191314630516
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HDAC6 IPO7 COPA RASA3 MYO19 FARSB VTA1 RFC4 NCAPG FBXO22 MDN1 PPP6C SBF1 EIF2B3 GEMIN4 ANKRD28 UTP20 ATIC HERC2 CTNND1 SNRNP200 EIF3M

5.87e-0613531912229467282
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CASP8AP2 ATP7A IPO8 IPO7 UACA LEMD3 CLASP2 ITPR2 THADA NCAPG MDN1 PPP6C SBF1 N4BP2 VPS13A DLG1 ANKRD28 HERC2 CTNND1 SNRNP200 PLS3 VPS13B SNTB2

8.00e-0614871912333957083
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

COPA UACA RFC4 NCAPG FBXO22 PPP6C HERC2 SNTB2

8.08e-06182191831067453
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

IPO8 IPO7 RNF213 ARFGEF3 THADA PPP6C EIF2B3 GEMIN4

8.41e-06183191823956138
Pubmed

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.

IPO8 COPA STK17B CUL7 H3-4 SYT10 TMPRSS11B PPP6C CTNND1 MARCHF11 GOLGA2 SNTB2

8.75e-064531911227113764
InteractionCOMTD1 interactions

COG2 IPO8 IPO7 STK17B APEX1 COG3 PPP4R3A THADA PPP6C EIF2B3 GEMIN4 ANKRD28 MAD2L2

5.85e-0820019013int:COMTD1
InteractionNPTN interactions

SMG1 COG2 CLTCL1 IPO8 RNF213 ACAD10 XRCC3 COG3 ARFGEF3 CFD THADA MDN1 GEMIN4 UTP20 MAD2L2

6.51e-0827819015int:NPTN
InteractionGPR17 interactions

COG2 IPO8 STK17B RNF213 COG3 ITPR2 ARFGEF3 GLMN THADA NCAPG MDN1 EIF2B3 GEMIN4 UBR3 UTP20

8.22e-0828319015int:GPR17
InteractionCYP2A7 interactions

CYP2A6 CYP2A7 CYP2A13

8.25e-0731903int:CYP2A7
InteractionSCN2B interactions

COG2 RNF213 COG3 THADA MDN1 PTPRD EIF2B3 UTP20

3.25e-06951908int:SCN2B
InteractionTACSTD2 interactions

STK17B RNF213 COG3 ARFGEF3 THADA MDN1 EIF2B3 GEMIN4 MAD2L2

3.77e-061291909int:TACSTD2
InteractionOCIAD1 interactions

COG2 CLTCL1 MYO19 CARMIL1 APEX1 RNF213 COG3 PPP4R3A TRAK1 THADA NCAPG INSC VPS13A UTP20 MAD2L2

1.10e-0541919015int:OCIAD1
InteractionVSIG2 interactions

COG2 IPO7 LEMD3 COG3 THADA

1.16e-05321905int:VSIG2
InteractionPCDHA9 interactions

PCDHA9 PCDHGB2 PCDHAC2 PCDHA10 PCDHA7

1.16e-05321905int:PCDHA9
InteractionC3orf18 interactions

SMG1 COG2 THADA NCAPG MDN1 EIF2B3 GEMIN4 UTP20

1.35e-051151908int:C3orf18
InteractionCD40 interactions

COG2 HDAC6 IPO8 RNF213 COG3 ARFGEF3 THADA GEMIN4 IKBKB

1.51e-051531909int:CD40
InteractionSLITRK1 interactions

FBXO22 PTPRD PTPRS

1.62e-0561903int:SLITRK1
InteractionANKRD20A4P interactions

ANKRD20A2P ANKRD20A4P ANKRD20A1

1.62e-0561903int:ANKRD20A4P
InteractionANKRD20A2P interactions

ANKRD20A2P ANKRD20A4P ANKRD20A1

2.81e-0571903int:ANKRD20A2P
InteractionGPR45 interactions

COG2 IPO8 HDHD5 MYO19 RNF213 ACAD10 XRCC3 COG3 THADA MDN1 GEMIN4 ANKRD28

2.92e-0530019012int:GPR45
InteractionRAB35 interactions

ATP7A HDAC6 MYO1D UACA EPB41L4B LEMD3 VPS13C CARMIL1 ARFGEF3 CFD SBF1 PTPRS VPS13A LRP2 DLG1 CTNND1 CD200

3.20e-0557319017int:RAB35
InteractionFZD10 interactions

IPO7 GLMN THADA NCAPG EIF2B3 GEMIN4

3.69e-05661906int:FZD10
InteractionMLNR interactions

IPO8 IPO7 STK17B MYO19 ACAD10 THADA

4.37e-05681906int:MLNR
InteractionFGF14 interactions

VPS13C EIF2B3 VPS13A GEMIN4 ANKRD28

4.53e-05421905int:FGF14
InteractionPCDHA10 interactions

PCDHA9 PCDHA13 PCDHA10 PCDHA7

4.90e-05221904int:PCDHA10
InteractionP2RY10 interactions

CLTCL1 ACAD10 COG3 ARFGEF3 GLMN THADA GEMIN4

6.58e-051061907int:P2RY10
InteractionFPR1 interactions

COG2 IPO8 STK17B RNF213 COG3 ARFGEF3 THADA GEMIN4

7.86e-051471908int:FPR1
InteractionRHOQ interactions

MYO1D ZFYVE16 LEMD3 VPS13C CARMIL1 CUL7 ARFGEF3 SBF1 PTPRS VPS13A LRP2 DLG1 CTNND1 SNTB2

8.17e-0544219014int:RHOQ
InteractionCCDC187 interactions

MCC ASB15 FBXO22 INSC ANKRD28 GOLGA2

8.20e-05761906int:CCDC187
InteractionSIGLECL1 interactions

IPO8 IPO7 RNF213 ARFGEF3 THADA EIF2B3 GEMIN4

9.86e-051131907int:SIGLECL1
InteractionCALM3 interactions

HDAC6 MYO1D VPS13C APEX1 CUL7 PPEF2 ITPR2 CFD VPS13A DLG1 LTK EIF3M

1.06e-0434319012int:CALM3
InteractionRHOJ interactions

MYO1D ZFYVE16 RASA3 LEMD3 VPS13C CARMIL1 CUL7 NPHP4 ARFGEF3 MDN1 SBF1 PTPRS VPS13A DLG1 UTP20 GOLGA2 SNTB2

1.09e-0463319017int:RHOJ
InteractionWHRN interactions

MCC ANKRD28 MYO15A GOLGA2

1.13e-04271904int:WHRN
InteractionBTNL9 interactions

IPO8 IPO7 THADA NCAPG SBF1 EIF2B3 GEMIN4 MAD2L2

1.19e-041561908int:BTNL9
InteractionANKRD20A1 interactions

ANKRD20A2P ANKRD20A4P ANKRD20A1

1.29e-04111903int:ANKRD20A1
InteractionTNFSF13B interactions

IPO8 IPO7 ARFGEF3 NCAPG MDN1 EIF2B3 GEMIN4

1.36e-041191907int:TNFSF13B
InteractionMYO5A interactions

HDAC6 MYO19 APEX1 DTNBP1 NPHP4 TRAK1 LRRIQ1 PLS3 FHIP2B

1.42e-042041909int:MYO5A
InteractionEFNB1 interactions

IPO8 IPO7 RNF213 ACAD10 TMPRSS11B THADA NCAPG SBF1 EIF2B3 MAD2L2

1.60e-0425519010int:EFNB1
InteractionTNPO1 interactions

TCEA2 IPO8 IPO7 CUL7 XRCC3 H3-4 TMPRSS11B NCAPG CLEC16A SNRNP200 TMEM255A

1.62e-0430619011int:TNPO1
InteractionRHPN1 interactions

CNKSR1 PPP4R3A MINDY3 GOLGA2 SNTB2

1.68e-04551905int:RHPN1
InteractionUNC93B1 interactions

COG2 IPO8 COPA RNF213 COG3 ITPR2 GLMN CFD THADA MDN1 PPP6C EIF2B3 GEMIN4

1.72e-0441719013int:UNC93B1
InteractionWDTC1 interactions

IPO8 COPA STK17B VPS13C CUL7 H3-4 SYT10 GLMN SEPTIN3 PPP6C MAD2L2 CTNND1 MARCHF11 GOLGA2 SNTB2

1.75e-0453519015int:WDTC1
InteractionPPFIA1 interactions

CNKSR1 PPFIBP2 APEX1 FBXO22 PPP4C PTPRD PTPRS LTK HERC2

2.03e-042141909int:PPFIA1
InteractionCD274 interactions

COG2 IPO8 IPO7 COPA FARSB APEX1 CLASP2 COG3 THADA UTP20 SNRNP200 PLS3

2.08e-0436919012int:CD274
InteractionRYR2 interactions

RYR1 RYR2 RYR3 SNTA1 GOLGA2

2.16e-04581905int:RYR2
InteractionKCNA3 interactions

DNHD1 ATP7A HDAC6 IPO7 MYO1D COPA ZFYVE16 CARMIL1 LAMA1 FARSB RNF213 ANKRD50 RYR1 VPS13A GEMIN4 LRP2 DLG1 CTNND1 SNRNP200 PLS3

2.22e-0487119020int:KCNA3
InteractionRHOF interactions

ATP7A HDAC6 IPO7 MYO1D UACA RASA3 LEMD3 ANKRD50 NCAPG MDN1 SBF1 VPS13A DLG1 UTP20 MAD2L2 VPS13B SNTB2

2.25e-0467319017int:RHOF
Cytoband5q31

PCDHA9 PCDHGB2 CDKL3 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

5.79e-0711519175q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA9 PCDHGB2 CDKL3 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

2.70e-042981917chr5q31
GeneFamilyAnkyrin repeat domain containing

ANKK1 UACA ANKRD62 ANKRD20A2P ANKRD20A3P ANKRD50 ASB15 ANKRD6 ANKRD20A4P ANKEF1 ANKRD30A ANKRD28 POTEJ AGAP6 ANKRD20A1 PPP1R12C PPP1R27

3.21e-1224213517403
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2 RYR3

4.07e-0731353287
GeneFamilyClustered protocadherins

PCDHA9 PCDHGB2 PCDHAC2 PCDHA13 PCDHA10 PCDHA7

8.15e-0664135620
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

HDAC6 MYO1D ZFYVE16 RYR1 ARFGEF3 CSRNP3 ANKRD28 PPP1R12C PPP1R27

8.77e-061811359694
GeneFamilyPDZ domain containing

CNKSR1 GIPC2 FRMPD2 CNKSR2 CNKSR3 DLG1 SNTA1 SNTB2

1.87e-0515213581220
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPEF2 PPP4C PPP6C

1.10e-04131353693
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SIGLEC12 BOC HSPG2 HMCN2 PTPRD PTPRS

1.33e-031611356593
GeneFamilyComponents of oligomeric golgi complex

COG2 COG3

1.50e-0381352493
GeneFamilyMyosins, class I

MYO1G MYO1D

1.50e-03813521097
GeneFamilyBiogenesis of lysosomal organelles complex 1 |BLOC-1 related complex

BLOC1S1 DTNBP1

1.50e-0381352452
GeneFamilyCytochrome P450 family 2

CYP2A6 CYP2A7 CYP2A13

2.24e-033513531001
GeneFamilySterile alpha motif domain containing

CNKSR1 PPFIBP2 CNKSR2 CNKSR3

4.27e-03881354760
GeneFamilyEF-hand domain containing

MCC PPEF2 RYR2 RYR3 ANKEF1 PLS3

6.07e-032191356863
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EPB41L4B FRMPD2 MYO15A

6.18e-035013531293
GeneFamilyCadherin related

CLSTN3 CLSTN2

6.99e-0317135224
GeneFamilyArmadillo repeat containing|Importins

IPO8 IPO7

7.83e-03181352596
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 CNKSR2 RYR2 RYR3 ARFGEF3 COL24A1 SLC8A1 PTPRD LRP2 MYO15A

7.57e-09184191102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 CNKSR2 RYR2 RYR3 ARFGEF3 COL24A1 SLC8A1 PTPRD LRP2 MYO15A

7.57e-0918419110ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 CNKSR2 RYR2 RYR3 ARFGEF3 COL24A1 SLC8A1 PTPRD LRP2 MYO15A

7.57e-09184191102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO1D CNKSR2 CLSTN2 RYR2 COL24A1 LRRIQ1 PTPRD VPS13A DLG1

1.17e-07186191984ba666237c18189d7e7556bd92dd953af733c00
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CARMIL1 CNKSR2 CLSTN2 RYR2 SLC8A1 PTPRD CSRNP3 VPS13A DLG1

1.75e-0719519192e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G ATP7A PPFIBP2 VPS13C PPEF2 FZD7 SLC8A1 IKBKB

7.42e-071701918a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G ATP7A PPFIBP2 VPS13C PPEF2 FZD7 SLC8A1 IKBKB

7.42e-071701918ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CARMIL1 CNKSR2 CLSTN2 RYR2 SLC8A1 PTPRD VPS13A DLG1

1.71e-061901918d594da827e3c16644952b9589cc12b947ce36279
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CARMIL1 CNKSR2 CLSTN2 RYR2 COL24A1 SLC8A1 PTPRD VPS13A

1.85e-0619219185c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDH26 RGS11 ANKRD20A3P SYT10 FAM135B CDK5R1 INSC

6.00e-06160191714dfa519e68bab4bce890ddb66fa7763f18d9f19
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDH26 RGS11 ANKRD20A3P SYT10 FAM135B CDK5R1 INSC

6.00e-061601917839bbdfd4e4c7b48260c8bfb7670378634405e1d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDH26 RGS11 ANKRD20A3P SYT10 FAM135B CDK5R1 INSC

6.00e-0616019175b7789d4668ed7732babedc32d812233b430e0bd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDH26 RGS11 ANKRD20A3P SYT10 FAM135B CDK5R1 INSC

6.00e-061601917bba1486faaad5299e10f4fe17c6d149c28dc2560
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

CYP2A6 XDH COG3 ASB15 F13B HMCN2 EDEM1

9.27e-061711917c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

BOC MYO1D ST3GAL5 PTPRS PLS3 SNTA1 CD200

1.00e-051731917c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC CYP2A6 CYP2A7 CYP2A13 PCDHAC2 TRAK1 MUC5AC

1.04e-05174191742f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 SYT10 ITPR2 COL24A1 TBC1D14 ANKRD30A TMEM255A

1.08e-0517519171d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellwk_15-18-Epithelial-PNS-intermediate_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CLSTN2 ANKRD20A4P INSC ANKRD28 TMEM255A ANKRD20A1 FDXACB1

1.44e-051831917d874aa9a856f79626c8a8371f6196a77b7d662ee
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC CYP2A6 CYP2A7 ANKRD6 LRP2 MUC5AC FHIP2B

1.66e-051871917f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

MYO1D CLASP2 RYR2 RYR3 SLC8A1 HMCN2 PLS3

1.71e-05188191734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPB41L4B CARMIL1 CNKSR2 RYR2 PTPRD VPS13A DLG1

1.77e-051891917a75226616340045b581d08429d2e123e041dee55
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CARMIL1 CNKSR2 CLSTN2 RYR2 SLC8A1 PTPRD VPS13A

1.83e-05190191749e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

MYO1D ANKRD20A2P ANKRD20A3P ANKRD20A4P ST3GAL5 EDEM1 ANKRD20A1

1.90e-0519119173480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ZFYVE16 LEMD3 ANKRD50 ARFGEF3 N4BP2 DLG1 VPS13B

2.03e-051931917abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYO1D ZFYVE16 CHADL ARFGEF3 PTPRD LRP2 DLG1

2.10e-051941917cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EPB41L4B LAMA1 DNAH14 RYR3 HMCN2 PTPRD MYO15A

2.17e-051951917d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EPB41L4B LAMA1 DNAH14 RYR3 HMCN2 PTPRD MYO15A

2.17e-05195191719853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 PCDHGB2 ANKRD20A2P ANKRD20A3P RYR3 ANKRD20A4P

2.18e-051311916ff4e618bd944f852bbd34438f740187aca82460f
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

MYO1D CLASP2 MED13L ITPR2 UBR3 DLG1 VPS13B

2.47e-05199191794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PCDHA9 ANKRD62 PCDHA10 RGS11 CNKSR2 RYR2 INSC

2.55e-0520019170c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

UACA GBP7 RNF213 PIK3C2B CTNND1 SNTB2 CD200

2.55e-052001917edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PCDHA9 ANKRD62 PCDHA10 RGS11 CNKSR2 RYR2 INSC

2.55e-052001917522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PCDHA9 ANKRD62 PCDHA10 RGS11 CNKSR2 RYR2 INSC

2.55e-05200191794f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellNeuronal-Excitatory|Neuronal / cells hierarchy compared to all cells using T-Statistic

MYO1D CARMIL1 CNKSR2 CLSTN2 RYR2 PTPRD DLG1

2.55e-0520019174409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 SYT10 ITPR2 COL24A1 TBC1D14 ANKRD30A

6.01e-051571916c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

HSPG2 RYR1 PTPRS CNKSR3 LTK SNTA1

6.44e-051591916ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 LAMA1 RYR2 RYR3 COL24A1 LRP2

6.67e-051601916c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 SYT10 ITPR2 COL24A1 TBC1D14 ANKRD30A

6.67e-051601916174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 LAMA1 RYR2 RYR3 COL24A1 LRP2

6.67e-05160191625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellCOVID-19_Severe-multiplets|World / disease group, cell group and cell class

RGS11 NCAPG SEPTIN3 HMCN2 ANKRD20A1 PPP1R27

7.39e-0516319166db4271c2d47a9c333964f36d2c32207115e52cd
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

VPS13C XDH PCDHA7 MED13L RYR3 SNTA1

7.39e-051631916f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3_(Neuron.Gad1Gad2.Cplx3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TRPC5OS PLA2G4D F13B PDE11A

7.83e-055319149c6aba539d540211b2309da1af6a531f3275a49d
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3_(Neuron.Gad1Gad2.Cplx3)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TRPC5OS PLA2G4D F13B PDE11A

7.83e-05531914846e031024ad3a4f5c6640b61cf4a0e69dbbcd1c
ToppCelldroplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIBP2 PPEF2 RYR1 THADA SEPTIN3 ST3GAL5

8.45e-051671916f33cef917fa733adf6d5a9a9e989a4d9fd462a8f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 MCC SYT10 ITPR2 TBC1D14 ANKRD30A

9.02e-0516919162a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCellsevere-HSPC|World / disease stage, cell group and cell class

ZNF805 CHADL ANKRD50 DNAH14 COL24A1 FAM124B

9.02e-051691916b0421b73bfdc92f7a2762b4b670b9eae124aa702
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 SYT10 ITPR2 COL24A1 TBC1D14 ANKRD30A

9.02e-0516919164b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 UACA XRCC3 NCAPG PTPRS PLS3

9.02e-0516919162833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 SYT10 ITPR2 COL24A1 TBC1D14 ANKRD30A

9.02e-051691916a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAD10 CHADL ANKRD6 AGXT SNTA1 FDXACB1

9.32e-051701916d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 FAN1 CDK5R1 THADA CNKSR3 CD200

9.32e-05170191655fe16d98ea284d05fb899888e4569c685644c7b
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

HSPG2 CNKSR1 MYO1D FAN1 ANKEF1 LTK

9.32e-051701916c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 MCC SYT10 ITPR2 TBC1D14 ANKRD30A

1.03e-0417319160bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 GIPC2 UACA ITPR2 PIK3C2B CD200

1.06e-04174191618ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MCC RYR3 COL24A1 ANKRD20A4P ANKRD20A5P ANKRD20A1

1.06e-04174191699eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP2A6 CYP2A7 GBP7 CFHR5 F13B AGXT

1.09e-0417519167f74961436f88c0e380819095e6104489914d765
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP2A6 CYP2A7 GBP7 CFHR5 F13B AGXT

1.09e-041751916bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 SYT10 ITPR2 COL24A1 TBC1D14 ANKRD30A

1.13e-041761916c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellPBMC-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

CARMIL1 RGS11 CLSTN2 SEPTIN3 SNTA1 CD200

1.16e-041771916974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B BOC MYO1D CLSTN2 SYT10 CD200

1.16e-041771916da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell3'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO1G GDAP1 UTP20 FAM124B FDXACB1 PPP1R27

1.16e-04177191634458f1eb7f3b1fd0cb9904529c01a9ca2f15500
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 UACA POLM CUL7 ANKRD28 TMEM255A

1.24e-041791916025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|368C / Donor, Lineage, Cell class and subclass (all cells)

RNF144B ACHE FARSB ANKRD6 NCAPG TRMT1L

1.24e-041791916ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MCC ANKRD62 CLSTN2 RYR3 COL24A1 ANKRD20A1

1.24e-041791916f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCDHA9 ANKRD62 RGS11 ADARB2 PTPRD INSC

1.24e-041791916dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPB41L4B WDR27 CUL7 CFD SBF1 GEMIN4

1.27e-0418019167368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F13B ARFGEF3 PPP6C INSC MAD2L2 EDEM1

1.31e-04181191657f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA MCC ITPR2 PIK3C2B FAM124B CD200

1.31e-04181191692d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 RIPOR3 CLSTN2 ADARB2 SYT10 CD200

1.31e-0418119169d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 SYT10 ITPR2 COL24A1 TBC1D14 ANKRD30A

1.31e-04181191630729f0364f719c044712a51453e22dc2c1a232b
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MCC FARSB CNKSR2 THADA FAM124B CD200

1.31e-0418119169275531e896e118cee043ed94fd31a0070d9581c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGS11 CNKSR2 CLASP2 ARFGEF3 SEPTIN3 PTPRS

1.31e-0418119167f99002a6411117cc2361334c7c9228e20c574b4
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F13B ARFGEF3 PPP6C INSC MAD2L2 EDEM1

1.31e-041811916d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 RIPOR3 CLSTN2 ADARB2 SYT10 CD200

1.35e-041821916eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellNS-moderate-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNF144B GBP7 RNF213 ITPR2 SLC8A1 ST3GAL5

1.35e-041821916e03e995e5fd14fc6a7559b83c0ca4e7ccc8e3d0f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MCC ANKRD62 CLSTN2 RYR3 COL24A1 ANKRD20A1

1.39e-04183191665f2a5895d166189a095cf7ea9dda171f0419b08
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IPO7 GBP7 MCC PIK3C2B CNKSR3 CD200

1.44e-041841916c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A4P ST3GAL5 EDEM1 ANKRD20A1

1.44e-04184191642d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCellwk_08-11-Epithelial-PNS-PCP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CYP2A6 RGS11 CNKSR2 CLSTN2 SEPTIN3 MARCHF11

1.44e-041841916eac2a9089913f33a961ba11519b53645790f2056
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 CDKL3 ARFGEF3 LRP2 ANKRD28 HMGXB3

1.52e-041861916e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCelldroplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 CDKL3 ARFGEF3 LRP2 ANKRD28 HMGXB3

1.52e-0418619164c0b59d845b79323e7a3287e7c4d249f5f322556
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A4P ST3GAL5 EDEM1 ANKRD20A1

1.52e-041861916962c2dada19185628ead77c32fcb07fa95114247
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCDHA9 UACA ANKRD62 PCDHA10 RGS11 RYR2

1.52e-041861916888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

COPA ZFYVE16 STK17B ITPR2 SLC8A1 DLG1

1.57e-0418719160099def970fbc828756fbf853eca2ce77b8cd342
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BOC HSPG2 PCDHA9 FZD7 COL24A1 PTPRD

1.61e-041881916b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

MYO1D ANKRD20A2P ANKRD20A3P ANKRD20A4P ST3GAL5 ANKRD20A1

1.61e-04188191647bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A4P ST3GAL5 EDEM1 ANKRD20A1

1.61e-0418819162331a2bae1383820d598e93aa86c75b101069bac
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

STK17B PPFIBP2 PTPRD PTPRS INSC CD200

1.66e-04189191646c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC PPFIBP2 SYT10 RYR2 COL24A1 PTPRS

1.66e-04189191645e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

RNF144B HSPG2 GIPC2 MCC RGS11 PIK3C2B

1.71e-041901916f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCellfacs-Thymus-Epithelium-24m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B BOC GDAP1 PCDHAC2 CFD HR

1.76e-041911916eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B BOC GDAP1 PCDHAC2 CFD HR

1.76e-0419119161730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCellhematopoetic_progenitors-CD34+_CLP|World / Lineage and Cell class

APEX1 MED13L COL24A1 PTPRD ANKRD28 CD200

1.76e-04191191632f2537c97c9984629d61c6f34a337f555146ad4
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2A6 CYP2A7 CDH26 XDH ARFGEF3 PTPRD

1.76e-04191191623776c7302cead3881b39127398f3b3e0d27885e
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GBP7 MCC PIK3C2B CNKSR3 CTNND1 CD200

1.76e-041911916a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 GIPC2 UACA PIK3C2B PLS3 CD200

1.76e-04191191604c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B BOC GDAP1 PCDHAC2 CFD HR

1.76e-0419119164b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 GIPC2 UACA PIK3C2B PLS3 CD200

1.76e-041911916db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

CARMIL1 RIPOR3 CLSTN2 CFD PTPRD PTPRS

1.76e-04191191670c067c54084bfb02c29bab085f4defd477194fb
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

CARMIL1 RIPOR3 CLSTN2 CFD COL24A1 PTPRS

1.81e-041921916356160b113c3305a61ceeaff33ce3c9da0be2878
Drugcis-diammineplatinum(II

RYR1 RYR2 RYR3

5.63e-0731893CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR2 RYR3

5.63e-0731893CID002750949
Drug8N3-cADPR

RYR1 RYR2 RYR3

5.63e-0731893CID000127713
Drugaminodantrolene

RYR1 RYR2 RYR3

5.63e-0731893CID009570289
Drug2-hydroxycarbazole

RYR1 RYR2 RYR3

5.63e-0731893CID000093551
Drug2'-methoxyacetophenone

CYP2A6 CYP2A7 CYP2A13

5.63e-0731893CID000068481
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR2 RYR3

5.63e-0731893CID005748312
Drug4,4'-dithiodipyridine

CYP2A6 APEX1 XDH RYR1 RYR2 RYR3

1.88e-06451896CID000075846
DrugPCB74

RYR1 RYR2 RYR3

2.24e-0641893CID000036218
Drug148504-47-6

RYR1 RYR2 RYR3

2.24e-0641893CID006444275
DrugSC 38249

RYR1 RYR2 RYR3

2.24e-0641893CID000134834
DrugAC1L1U7A

RYR1 RYR2 RYR3

2.24e-0641893CID000035682
DrugCarbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A

PCDHA9 PPFIBP2 MCC CLSTN2 SBF1 AGXT SHCBP1L MUC5AC SNTA1 VPS13B

6.44e-06198189102623_UP
DrugIsoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CNKSR1 HDAC6 STK17B ANKRD6 TRAK1 CFD MINDY3 FBXO22 SBF1 HMGXB3

7.04e-06200189104789_DN
DrugCarteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A

COPA RASA3 CLASP2 CLSTN2 ANKRD6 ITPR2 MINDY3 EXD3 SBF1 HMGXB3

7.04e-06200189103276_DN
Drugparathion

CYP2A6 CYP2A7 CYP2A13 ACHE CLSTN2 CFD VPS13A

1.09e-05911897CID000000991
Drugchloro-m-cresol

RYR1 RYR2 RYR3

1.11e-0561893CID000012008
DrugMBED

RYR1 RYR2 RYR3

1.11e-0561893CID000129958
DrugAC1O528X

RYR1 RYR2 RYR3

1.11e-0561893CID006475857
DrugNSC114784

RYR1 RYR2 RYR3

1.11e-0561893CID000419425
Drugmethylcoumarin

BOC RYR1 RYR2 RYR3

1.29e-05181894CID000007092
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR2 RYR3

1.92e-0571893CID009547999
DrugAzumoleno

RYR1 RYR2 RYR3

1.92e-0571893CID000056259
DrugBr2BAPTA

RYR1 RYR2 RYR3

1.92e-0571893CID003081001
DrugTTNPB; Up 200; 0.1uM; MCF7; HG-U133A

TCEA2 CNKSR1 CLSTN3 CDKL3 ADARB2 TRAK1 GLMN MINDY3 IKBKB

3.12e-051901899223_UP
Drug(+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA

CUL7 NPHP4 PPP4R3A FAN1 VPS13A LRP2 HMGXB3 SNRNP200 EIF3M

3.68e-051941899954_UP
Drugsodium 4-phenylbutyrate; Down 200; 1000uM; PC3; HG-U133A

TCEA2 HSPG2 RASA3 LEMD3 CDKL3 GLMN PPP4C SBF1 AGXT

3.83e-051951899434_DN
DrugMolsidomine [25717-80-0]; Down 200; 16.6uM; HL60; HG-U133A

STK17B GMIP NPHP4 TRAK1 MINDY3 PIK3C2B GEMIN4 CLEC16A EIF3M

4.15e-0519718991711_DN
DrugFamotidine [76824-35-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CDKL3 MCC CLASP2 CLSTN2 XRCC3 SBF1 ST3GAL5 EIF3M GOLGA2

4.15e-0519718991529_DN
DrugIsopyrin hydrochloride [18342-39-7]; Down 200; 14.2uM; MCF7; HT_HG-U133A

IPO8 ZFYVE16 TRAK1 ITPR2 FZD7 EXD3 SBF1 VPS13A CLEC16A

4.49e-0519918997233_DN
Drugts M

ACHE RYR1 RYR2 RYR3 CFD

4.79e-05481895CID000428025
DrugPCB 95

RYR1 RYR2 RYR3

6.47e-05101893CID000038012
Drugtert-butylmagnesium chloride

ACHE CFD

6.85e-0521892CID000101830
Drugpropargyl ether

CYP2A6 CYP2A13

6.85e-0521892ctd:C531209
DrugHempa

CYP2A6 CYP2A13

6.85e-0521892ctd:D006492
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

6.85e-0521892ctd:C005147
DrugORF 17578

ACHE CFD

6.85e-0521892CID003037245
Drugnicotine imine

CYP2A6 CYP2A13

6.85e-0521892ctd:C034629
Drugalpha-nicotyrine

CYP2A6 CYP2A13

6.85e-0521892ctd:C008615
DrugN-nitrosoguvacoline

CYP2A6 CYP2A13

6.85e-0521892ctd:C036676
DrugAC1L9EL8

ACHE CFD

6.85e-0521892CID000443397
DrugPCB 66

RYR1 RYR2 RYR3

8.85e-05111893CID000036185
DrugTrimetazidine

ACHE RYR2 SLC8A1

8.85e-05111893ctd:D014292
DrugR 478

RYR1 RYR2 RYR3

8.85e-05111893CID000084223
Drug8-amino-cADPR

RYR1 RYR2 RYR3

8.85e-05111893CID003081323
Drugchloroacetyl chloride

BOC CYP2A6 CYP2A7 CYP2A13 CLSTN2

9.29e-05551895CID000006577
DrugRyanodine

RYR1 RYR2 RYR3

1.17e-04121893ctd:D012433
DrugAC1NUTUV

CYP2A6 XDH CD200

1.17e-04121893CID005460886
Diseasevisceral adipose tissue measurement, body mass index

PCDHA9 PCDHAC2 PCDHA13 PCDHA10 PCDHA7 CNKSR2 CLSTN2 MAD2L2

7.22e-08871838EFO_0004340, EFO_0004765
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2 RYR3

2.35e-0731833DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2 RYR3

2.35e-0731833DOID:8545 (implicated_via_orthology)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13C VPS13A VPS13B

2.35e-0731833DOID:0111590 (implicated_via_orthology)
Diseasemetal metabolism disorder (implicated_via_orthology)

ATP7A BLOC1S1 DTNBP1

9.34e-0741833DOID:896 (implicated_via_orthology)
DiseaseColorectal Carcinoma

BOC CYP2A6 CLSTN3 FRMPD2 LAMA1 MCC CNKSR2 CLSTN2 ADARB2 NCAPG PTPRD CSRNP3 PTPRS VPS13A LRP2 SNRNP200 HR

2.00e-0670218317C0009402
Disease1,5 anhydroglucitol measurement

PCDHA9 PCDHA13 PCDHA10 PCDHA7

3.01e-05291834EFO_0008009
DiseaseParkinson's disease 23 (implicated_via_orthology)

VPS13C VPS13A

3.83e-0521832DOID:0060896 (implicated_via_orthology)
Diseasechoreaacanthocytosis (implicated_via_orthology)

VPS13C VPS13A

3.83e-0521832DOID:0050766 (implicated_via_orthology)
Diseasecutaneous melanoma, hair color

GIPC2 RASA3 PPFIBP2 MED13L HERC2

4.22e-05621835EFO_0000389, EFO_0003924
Diseasevital capacity

HSPG2 PCDHA9 IPO8 EPB41L4B PCDHA13 WDR27 PCDHA10 PCDHA7 VTA1 RYR2 SLC8A1 LRRIQ1 PTPRD PIK3C2B AGXT LRP2 DLG1 FBXL20 NLRP4 PDE11A

9.03e-05123618320EFO_0004312
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13C VPS13A

1.14e-0431832DOID:0111611 (implicated_via_orthology)
Diseasecomplement C5 measurement

CFHR5 F13B

1.14e-0431832EFO_0020278
Diseaseplatelet-derived growth factor receptor alpha measurement

CFHR5 F13B

1.14e-0431832EFO_0021844
DiseaseMalignant neoplasm of breast

BOC ACHE XDH CFHR5 XRCC3 COG3 RFC4 FCRL3 PTPRD N4BP2 ANKEF1 ANKRD30A UTP20 HERC2 IKBKB PLS3 EIF3M VPS13B

1.34e-04107418318C0006142
DiseaseLung Diseases, Interstitial

COPA FARSB

2.28e-0441832C0206062
Diseaseangiotensinogen measurement

COG2 AGXT

2.28e-0441832EFO_0008025
DiseaseHypoplastic Left Heart Syndrome

PCDHA9 PCDHA13

3.78e-0451832C0152101
DiseaseIntellectual Disability

CNKSR1 LAMA1 MCC FARSB MED13L H3-4 ST3GAL5 IER3IP1 LRP2 ATIC

5.09e-0444718310C3714756
Diseaseneutrophil count, basophil count

MYO1G PCDHA9 PCDHA13 PCDHA10 PCDHA7 VTA1 THADA

5.20e-042241837EFO_0004833, EFO_0005090
DiseaseStrabismus

ZNF618 ADARB2 PTPRD

7.61e-04291833HP_0000486
Diseasealpha-1-antichymotrypsin complex measurement

CFD SERPINA13P

7.87e-0471832EFO_0008018
Diseasesusceptibility to mononucleosis measurement

ANKRD50 RYR2 MDN1 PTPRD

9.04e-04691834EFO_0008403
Diseasebitter non-alcoholic beverage consumption measurement

CYP2A6 N4BP2 FAM124B

1.02e-03321833EFO_0010093
Diseasepursuit maintenance gain measurement

MYO1G IPO7 CARMIL1 CNKSR2 PTPRD

1.04e-031231835EFO_0008433
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13C VPS13A

1.05e-0381832DOID:0050753 (implicated_via_orthology)
DiseaseAbnormality of refraction

SMG1 PCDHA9 MYO1D FRMPD2 PCDHA13 PCDHA10 PCDHA7 CNKSR2 ITPR2 SLC8A1 FBXO7 PDE11A

1.07e-0367318312HP_0000539
DiseaseSarcomatoid Renal Cell Carcinoma

DNHD1 ACHE CUL7 ASB15 RYR1

1.24e-031281835C1266043
DiseaseChromophobe Renal Cell Carcinoma

DNHD1 ACHE CUL7 ASB15 RYR1

1.24e-031281835C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

DNHD1 ACHE CUL7 ASB15 RYR1

1.24e-031281835C1266044
DiseasePapillary Renal Cell Carcinoma

DNHD1 ACHE CUL7 ASB15 RYR1

1.24e-031281835C1306837
DiseaseRenal Cell Carcinoma

DNHD1 ACHE CUL7 ASB15 RYR1

1.24e-031281835C0007134
DiseaseTremor, Neonatal

ATP7A ACHE

1.34e-0391832C0235843
DiseaseTremor, Perioral

ATP7A ACHE

1.34e-0391832C0235078
DiseaseNerve Tremors

ATP7A ACHE

1.34e-0391832C0235083
DiseaseTremor, Limb

ATP7A ACHE

1.34e-0391832C0235081
DiseaseTremor, Muscle

ATP7A ACHE

1.34e-0391832C0235082
DiseaseSenile Tremor

ATP7A ACHE

1.34e-0391832C0149840
DiseasePill Rolling Tremor

ATP7A ACHE

1.34e-0391832C0751564
DiseaseTremor, Semirhythmic

ATP7A ACHE

1.34e-0391832C0751565
DiseaseAction Tremor

ATP7A ACHE

1.34e-0391832C0234376
DiseasePassive Tremor

ATP7A ACHE

1.34e-0391832C0234377
DiseaseStatic Tremor

ATP7A ACHE

1.34e-0391832C0234378
DiseaseResting Tremor

ATP7A ACHE

1.34e-0391832C0234379
DiseaseIntermittent Tremor

ATP7A ACHE

1.34e-0391832C0234372
DiseaseFine Tremor

ATP7A ACHE

1.34e-0391832C0234373
DiseaseCoarse Tremor

ATP7A ACHE

1.34e-0391832C0234374
DiseaseMassive Tremor

ATP7A ACHE

1.34e-0391832C0234375
DiseasePersistent Tremor

ATP7A ACHE

1.34e-0391832C0234370
DiseaseContinuous Tremor

ATP7A ACHE

1.34e-0391832C0234371
DiseaseDarkness Tremor

ATP7A ACHE

1.34e-0391832C0234381
DiseaseInvoluntary Quiver

ATP7A ACHE

1.34e-0391832C1527384
DiseaseSaturnine Tremor

ATP7A ACHE

1.34e-0391832C0040827
Diseasepulmonary hypertension (biomarker_via_orthology)

RYR1 RYR2 RYR3 CTNND1

1.57e-03801834DOID:6432 (biomarker_via_orthology)
DiseaseProfound Mental Retardation

CNKSR1 LAMA1 MCC MED13L H3-4

1.79e-031391835C0020796
DiseaseMental Retardation, Psychosocial

CNKSR1 LAMA1 MCC MED13L H3-4

1.79e-031391835C0025363
DiseaseMental deficiency

CNKSR1 LAMA1 MCC MED13L H3-4

1.79e-031391835C0917816
Diseaseforced expiratory volume, response to bronchodilator

CYP2A6 CYP2A7 GIPC2 GDAP1 CNKSR2 CLSTN2 COL24A1 SLC8A1 PTPRD

1.93e-034451839EFO_0004314, GO_0097366
DiseaseTremor

ATP7A ACHE

2.03e-03111832C0040822
Diseasebitter beverage consumption measurement

CYP2A6 N4BP2 FAM124B

2.26e-03421833EFO_0010089
Diseaseeosinophil count

TCEA2 UACA STK17B PRXL2B TRMT112 CDKL3 ACAD10 GMIP GLMN THADA PPP4C MDN1 PIK3C2B TBC1D14 BTN2A3P MUC5AC CLEC16A SNRNP200 CD200

2.34e-03148818319EFO_0004842
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DNHD1 ACHE CUL7 ASB15 RYR1

2.35e-031481835C0279702
Diseasenicotine metabolite ratio

CYP2A6 CYP2A7

2.42e-03121832EFO_0007794
Diseasehippocampal volume

LEMD3 GDAP1 MED13L RYR2 RYR3 PTPRD PDE11A

2.63e-032971837EFO_0005035
Diseasefatty acid measurement, fetal genotype effect measurement, breast milk measurement

COG3 FAM135B

2.85e-03131832EFO_0005110, EFO_0007959, EFO_0009092
DiseaseCharcot-Marie-Tooth disease type 4

GDAP1 SBF1

2.85e-03131832cv:C4082197
Diseasepneumonia

GIPC2 EXD3 MUC5AC

3.11e-03471833EFO_0003106
Diseasefatty acid measurement, breast milk measurement, parental genotype effect measurement

COG3 FAM135B

3.31e-03141832EFO_0005110, EFO_0005939, EFO_0009092
DiseaseHermansky-Pudlak syndrome (implicated_via_orthology)

BLOC1S1 DTNBP1

3.31e-03141832DOID:3753 (implicated_via_orthology)
DiseaseGeneralized seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0234533
DiseaseClonic Seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0234535
DiseaseConvulsive Seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0751494
DiseaseSeizures, Sensory

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0751496
DiseaseNon-epileptic convulsion

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0751056
DiseaseAtonic Absence Seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0751123
DiseaseComplex partial seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0149958
DiseaseSingle Seizure

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0751110
DiseaseNonepileptic Seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C3495874
DiseaseVisual seizure

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0270824
DiseaseEpileptic drop attack

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0270846
DiseaseVertiginous seizure

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0422855
DiseaseGustatory seizure

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0422854
DiseaseSeizures, Somatosensory

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0422850
DiseaseOlfactory seizure

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0422853
DiseaseSeizures, Auditory

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0422852
DiseaseGeneralized Absence Seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C4505436
DiseaseJacksonian Seizure

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C0022333
DiseaseEpileptic Seizures

ATP7A ACHE APEX1 SLC8A1

3.66e-031011834C4317109
DiseaseAbsence Seizures

ATP7A ACHE APEX1 SLC8A1

3.79e-031021834C4316903
DiseaseConvulsions

ATP7A ACHE APEX1 SLC8A1

3.79e-031021834C4048158
DiseaseTonic Seizures

ATP7A ACHE APEX1 SLC8A1

3.79e-031021834C0270844
Diseasecerebral amyloid angiopathy

CYP2A6 MCC CNKSR2

3.93e-03511833EFO_0006790
DiseaseSeizures, Focal

ATP7A ACHE APEX1 SLC8A1

4.06e-031041834C0751495
DiseaseMyoclonic Seizures

ATP7A ACHE APEX1 SLC8A1

4.06e-031041834C4317123
DiseaseTonic - clonic seizures

ATP7A ACHE APEX1 SLC8A1

4.06e-031041834C0494475
Diseasepartial epilepsy

FZD7 PTPRD

4.89e-03171832EFO_0004263
DiseaseMoyamoya Disease

ATP7A RNF213

4.89e-03171832C0026654
Diseasepolyp of colon

BOC ACAD10 PIK3C2B

5.11e-03561833MONDO_0021400
Diseaseurate measurement, bone density

CASP8AP2 ZNF618 CARMIL1 MCC RIPOR3 CLASP2 DTNBP1 DNAH14 ITPR2 PTPRD

5.48e-0361918310EFO_0003923, EFO_0004531
Diseasebrain infarction

GIPC2 EIF2B3

5.48e-03181832EFO_0004277

Protein segments in the cluster

PeptideGeneStartEntry
QEEACAVILLEHGAN

ANKRD20A1

111

Q5TYW2
REALSDVVGDHNVVC

ACHE

426

P22303
CNEAILHLVVAGLDS

BTN2A3P

131

Q96KV6
VGSDHELQAVLLTCL

CDK5R1

216

Q15078
IVHNLDGCEISLVGD

CLSTN3

701

Q9BQT9
LCGHDAVREALVDQA

CYP2A6

81

P11509
CLTEALVDHLNVGVA

BLOC1S1

61

P78537
QEEACAVILLEHGAN

ANKRD20A4P

111

Q4UJ75
EQVRLLLAHEVDVDC

ANKK1

376

Q8NFD2
LLLDHGACVDAQERE

ANKK1

446

Q8NFD2
NGLLADIVHACLQID

CDKL3

256

Q8IVW4
LLAVNNVCLEEVTHE

DLG1

371

Q12959
QEEACAVILLEHGAN

ANKRD20A5P

111

A0PJZ0
NDVHCTEVLLAAGAD

ASB15

361

Q8WXK1
CVNGHEEVVTFLVDR

ANKRD30A

81

Q9BXX3
NGHETCVELLLEQEV

ANKRD28

766

O15084
QEEVCASILLEHGAN

ANKRD62

116

A6NC57
CKIHSVDLQAVGLED

ACAD10

396

Q6JQN1
CHAGQQDIVELLVES

ANKEF1

566

Q9NU02
ICVGDHIESINGENI

GIPC2

156

Q8TF65
FEGHRLICEALIEQG

ANKRD50

856

Q9ULJ7
ATALCIAAQEGHIDV

ANKRD50

1046

Q9ULJ7
CLGIVGAQVALEEAV

DNHD1

196

Q96M86
VLCGDLNVAHEEIDL

APEX1

206

P27695
LHNLDFCDILVIGGD

CLSTN2

691

Q9H4D0
IEVTVLHIDQLGCSG

CASP8AP2

1701

Q9UKL3
IAALIHEGCALDRQD

ANKRD6

91

Q9Y2G4
ILLLAHGSCEEVNET

AGAP6

581

Q5VW22
VAVDDELCGLIAIAD

ATP7A

1216

Q04656
RVVQELLEHGVCEEV

POLM

211

Q9NP87
AGHCTLLVEVVDVND

PCDHA9

331

Q9Y5H5
SHVAEGETLDLNCVV

HSPG2

2736

P98160
AHILGEVCREKQEAA

RASA3

321

Q14644
LSDQGLVVNDCHAEV

ADARB2

421

Q9NS39
CVSEEEALHLGAVLV

RGS11

66

O94810
AALLCVNAIAVLHEE

IER3IP1

11

Q9Y5U9
LFHVCEDLENIEGLH

PPP4R3A

176

Q6IN85
CIATHESNGIDIIIA

ITPR2

2006

Q14571
AACQLHGGLELEEET

KASH5

106

Q8N6L0
LEKCSDNDGIVHIAV

LEMD3

811

Q9Y2U8
LNHGTLQEAEIACLV

RNF144B

81

Q7Z419
QEEACAVILLEHGAN

ANKRD20A2P

111

Q5SQ80
HCLEDAADGKVQVLL

CFD

66

P00746
AGHCTVLVEVVDVND

PCDHA7

331

Q9UN72
GHCLVRVVAEELENV

FBXO22

81

Q8NEZ5
CQVEHSSALAVEELG

MINDY3

131

Q9H8M7
VGNSVCDILLALHTE

MDN1

2336

Q9NU22
LHGELLETCVVNIAL

MED13L

1846

Q71F56
ADVLCEFLEVAVHLI

MAD2L2

16

Q9UI95
EELVAEAHNLCTLLE

IKBKB

706

O14920
IDIAQEEVLTCLGIH

GGNBP2

291

Q9H3C7
EQGLELCRVVAVHVE

MYO15A

3496

Q9UKN7
VLSQLEACGLVETIH

MYO19

636

Q96H55
VHEDEILVGLCRVAI

NLRP11

326

P59045
CTAEIEHRALDVQGI

GMIP

571

Q9P107
LVEALQGHRVVDIAC

HERC2

4136

O95714
HVLEGQEVRLDCEAD

HMCN2

3236

Q8NDA2
CATAHIGGVNIVLLE

KIAA1109

2826

Q2LD37
GGLHVDLAQIIEACD

EIF3M

36

Q7L2H7
AVLHLQSAEELDCQG

CSRNP3

326

Q8WYN3
LCVEVADLVSILVHA

HR

1006

O43593
QCLAVEALAEEVGAL

HMGXB3

181

Q12766
AVLCHDGILVVEVKD

HSPB3

131

Q12988
QLVCLGESRAVEEHA

LTK

176

P29376
EIVHIECELNFEIHG

F13B

296

P05160
AIGCHVVNIGAEDLR

PLS3

206

P13797
HQTLLQGVVVLEEFC

FHIP2B

701

Q86V87
GEDAECHAAKLLEVI

IPO7

731

O95373
LCHAEVQVGDQLETV

KPTN

146

Q9Y664
DLAAHCSIQVEILDD

PCDHGB2

326

Q9Y5G2
EVEILAVIVGCLCHD

PDE11A

691

Q9HCR9
EGLHIDQLVCLVLEA

CUL7

1581

Q14999
EEVENNLLHLEDLCG

DTNBP1

126

Q96EV8
IHGENIICEATQIID

GDAP1

81

Q8TB36
ELLDVHAVCEREAIA

GBP7

351

Q8N8V2
LVGLFEDTNLCVIHA

H3-4

101

Q16695
EDARLCHILEEVAGL

LMNTD2

86

Q8IXW0
NTLDHTGVVVLCEAL

NLRP4

931

Q96MN2
GNLEHLECVTLDIEE

LRP2

1916

P98164
DLGQDVICSHTEGLI

MUC5AC

1636

P98088
VEELEHRCIQLSGET

GOLGA2

826

Q08379
DLEVCLEGHQVKLNA

PPFIBP2

141

Q8ND30
HIEAIECENLENLCV

LRRIQ1

851

Q96JM4
GVLEVLSEVECHLRV

NPHP4

46

O75161
IHVEGLNVCLENVIG

SBF1

156

O95248
IHEALLEAVGCGNTE

PTPRS

1641

Q13332
HLGDEVNLKVTVLCD

PIK3C2B

371

O00750
EVICQVLHLGTVTDF

CD200

211

P41217
AGHCTLLVEVLDVND

PCDHA13

331

Q9Y5I0
GHCTVLVELLDENDN

PCDHA10

331

Q9Y5I2
AGHCKVLVDIVDVND

PCDHAC2

346

Q9Y5I4
VAHVAGFLLEDRAVC

FZD7

301

O75084
CDLITDVALHEVVDL

EIF2B3

106

Q9NR50
QEEACAVILLEHGAN

ANKRD20A3P

111

Q5VUR7
HCDLAIKTVEEIEGV

MCC

201

P23508
LQHLETCLLQVVGEG

IFNW1

116

P05000
TISECLLHLQVQGEE

FAM124B

431

Q9H5Z6
HVIEVDEGNTAVIAC

BOC

136

Q9BWV1
LCGHDAVKEALVDQA

CYP2A13

81

Q16696
DCSDANDALIVLIHL

FBXO7

191

Q9Y3I1
LCGHDAVREALVDQA

CYP2A7

81

P20853
LCGILKNEVLEDHVQ

COG3

426

Q96JB2
LALECGNIEIALEAA

COPA

651

P53621
VVLLNGQHLEVKCDV

FRMPD2

346

Q68DX3
HAIGLSCELVVEHIQ

ARFGEF3

1531

Q5TH69
GLIHLEGDTVQIICN

CFHR5

101

Q9BXR6
RDNLEACISGLHVDV

DNAH14

836

Q0VDD8
QVLIGDVEDAICLHA

EDEM1

446

Q92611
QAVVGDLLELHCESL

FCRL3

486

Q96P31
DLVCIGLIVHEGAAV

MARCHF11

291

A6NNE9
LTCVELADAEVGLHV

CDH26

601

Q8IXH8
HQLEKVDGVLCLADI

INSC

316

Q1MX18
AQVLEGCIAEIHNIT

CARMIL1

471

Q5VZK9
LEGLQTSDVDIIRHC

COG2

216

Q14746
EEENLEDGIHLVVCV

FAM135B

1131

Q49AJ0
TGLVLDEQLNEFHCL

HDAC6

86

Q9UBN7
LDLRHCEVELVAEGA

CHADL

91

Q6NUI6
CADVLAEEGEVHVAL

FDXACB1

111

Q9BRP7
QDLLAHCGIQLDGEE

RYR1

2036

P21817
EASSGILEVLHCVLV

RYR2

566

Q92736
AVELAALCLQAELGE

EPB41L4B

201

Q9H329
CDGLVDALIFIVQAE

CTNND1

551

O60716
EEVDCLVLQLHRVGE

MIF4GD

146

A9UHW6
VCGDLHGQLDDLIFI

PPEF2

176

O14830
HDALLEAVTCGNTEV

PTPRD

1606

P23468
EELAVHLGFNLCAEE

PLA2G4D

276

Q86XP0
GEDAECHAAKLLEVI

IPO8

731

O15397
ICSLRDHEAVVGQLA

RNF186

96

Q9NXI6
LAELQKLGAEVEVCH

FAN1

991

Q9Y2M0
CIEEGHTDQLLEIIQ

GLMN

36

Q92990
ACILKHAVTGEAVEL

PRXL2B

11

Q8TBF2
ECHSAVIQAVEDLDL

UTP20

1071

O75691
GADEHLQLISLCATV

RFC4

341

P35249
SGHCALEAALVNVLE

AGXT

81

P21549
CNKGIEVLFAVALEH

TRMT1L

446

Q7Z2T5
LVECIGVEHILAIDK

THADA

461

Q6YHU6
LVDGCHRAAEGVQEV

SNTA1

396

Q13424
GISALHQACIDENLE

PPP1R12C

101

Q9BZL4
CAIVDGVFAARHIDL

TMEM255A

106

Q5JRV8
LGNGACAHDQLEVIE

FBXL20

346

Q96IG2
NAIDLVVAADVEHCE

LAMA1

696

P25391
LLGCEVDADQVILSH

HDHD5

106

Q9BXW7
HLISQCEQLEGEVGA

SMG1

2611

Q96Q15
FCEEQNTGILHDEIL

POTEJ

566

P0CG39
QDCRAEILHEIAVLE

STK17B

71

O94768
GQDTDIHVIALALEV

SHCBP1L

241

Q9BZQ2
IGVIAVVLATHLCDE

ST3GAL5

341

Q9UNP4
VLEGQSLHLVCAVDS

SIGLEC12

391

Q96PQ1
ADIIHACDIVEDAAI

FARSB

356

Q9NSD9
LLLQDCGVHVQVAEG

ACD

96

Q96AP0
REDQEHQGALVCLAE

ACD

176

Q96AP0
LCGLHIVIHADELEE

CLTCL1

1271

P53675
VTEEDVQLRHCLGVF

NCAPG

741

Q9BPX3
LACLEGAREESVHLV

CLEC16A

586

Q2KHT3
VFCLVAVHAVIGDEL

CLASP2

1241

O75122
IGHQELVLEAVDLLC

CNK3/IPCEF1

56

G9CGD6
VLCAAVELLHEADAL

CNKSR1

111

Q969H4
GHQELILEAVDLLCA

CNKSR2

61

Q8WXI2
IGHQELVLEAVDLLC

CNKSR3

56

Q6P9H4
NSIHFEGIVCQLDII

COL24A1

211

Q17RW2
CAVENEELVQHLGAA

TRAK1

301

Q9UPV9
AALHEAVLSGNLECV

PPP1R27

66

Q86WC6
GNELNITHELFDICL

TBC1D14

416

Q9P2M4
VVLLLGLLNEDDACH

RNF213

3561

Q63HN8
QHEEIIGKVCELINE

ZNF618

821

Q5T7W0
HLVGDCELSVVEILV

VPS13A

896

Q96RL7
GLHDDIALVQLAEEV

TMPRSS11B

266

Q86T26
KEVTLIEELHCAGQA

RIPOR3

786

Q96MK2
VAALIDEQILCVHGG

PPP6C

151

O00743
HLLLEVEVIEGTLQC

TRMT112

86

Q9UI30
DNEAITQEIVGCAHL

VTA1

76

Q9NP79
DCELQHRVEAIVAFG

RYR3

1816

Q15413
IIEVENLNHCEFALL

SEPTIN3

286

Q9UH03
IHVLIDGLVACVAQL

TRPC5OS

6

A6NMA1
GAHCVALVDQEASDL

SERPINA13P

16

Q6UXR4
ELLQDVCAGLAEELH

XDH

481

P47989
GIEHSLIEENCGVVV

VPS13C

2266

Q709C8
VIEACDELGIILAHT

ATIC

571

P31939
ALHIVTELCFAGQVE

SYT10

16

Q6XYQ8
LECLNAILIHGVDIT

UACA

81

Q9BZF9
VAELTGDHQLCKEEI

SNRNP200

566

O75643
ENSLHVVVNCGEALL

UBR3

491

Q6ZT12
TEEILVCGHSLEVNI

VPS13B

1716

Q7Z7G8
HVAIGADCERLSAQI

TCEA2

156

Q15560
VLCLQLSLDDHVVAV

WDR27

126

A2RRH5
ILVQGCHAAAELIKE

SNTB2

431

Q13425
CGNVAAILELDEHLQ

PPP4C

266

P60510
IEHVADVDTLLECVN

XRCC3

181

O43542
IIQDRVSLGDDVHDC

ZNF805

171

Q5CZA5
IGESHGINIICEIVD

ZFYVE16

586

Q7Z3T8
HILELLCEIVSANAE

GEMIN4

731

P57678
EDGILEANHVSTLAC

SLC8A1

506

P32418
EQQHKGIIAILDDAC

MYO1D

446

O94832
DNRVGELVGVLAAHC

MYO1G

951

B0I1T2
EGALLQCHQVVGVDV

EXD3

386

Q8N9H8
SLTVEDCVVHIDLNL

N4BP2

1401

Q86UW6