Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycogen synthase activity, transferring glucose-1-phosphate

GYS1 GYS2

1.07e-0422072GO:0061547
GeneOntologyMolecularFunctionbone sialoprotein binding

ANXA2 ANXA2P2

1.07e-0422072GO:0044730
Domain-

LRRK2 TEX10 TRRAP GCN1 SCYL3 APC HEATR5A FRYL PKP3 MROH2B CFAP69

3.57e-05222205111.25.10.10
DomainWD40

DPH7 EML6 LRRK2 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

4.26e-0526820512SM00320
DomainARM-like

LRRK2 TEX10 TRRAP GCN1 SCYL3 APC HEATR5A FRYL PKP3 MROH2B LTN1 CFAP69

4.57e-0527020512IPR011989
DomainWD40_repeat

DPH7 EML6 LRRK2 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

4.91e-0527220512IPR001680
DomainNeurexophilin

NXPE4 NXPE1 NXPE2

7.01e-0582053PF06312
DomainNXPH/NXPE

NXPE4 NXPE1 NXPE2

7.01e-0582053IPR026845
DomainARM-type_fold

LRRK2 TEX10 TRRAP GCN1 DOCK3 SCYL3 APC HEATR5A FRYL PKP3 MROH2B LTN1 CFAP69

9.97e-0533920513IPR016024
DomainWD40_repeat_dom

DPH7 EML6 LRRK2 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

1.14e-0429720512IPR017986
DomainGlycogen_syn

GYS1 GYS2

1.20e-0422052PF05693
DomainGlycogen_synth

GYS1 GYS2

1.20e-0422052IPR008631
DomainWD40

DPH7 EML6 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

1.42e-0425920511PF00400
DomainWD_REPEATS_1

DPH7 EML6 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

2.62e-0427820511PS00678
DomainWD_REPEATS_2

DPH7 EML6 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

2.70e-0427920511PS50082
DomainWD_REPEATS_REGION

DPH7 EML6 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

2.70e-0427920511PS50294
Domain-

DPH7 EML6 LRRK2 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

3.26e-04333205122.130.10.10
DomainWD40/YVTN_repeat-like_dom

DPH7 EML6 LRRK2 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

3.44e-0433520512IPR015943
DomainVPS13

VPS13A VPS13D

3.57e-0432052IPR026847
DomainVPS13_mid_rpt

VPS13A VPS13D

3.57e-0432052PF16910
DomainVPS13

VPS13A VPS13D

3.57e-0432052PF16908
DomainVPS13_N2

VPS13A VPS13D

3.57e-0432052IPR031646
DomainVPS13_mid_rpt

VPS13A VPS13D

3.57e-0432052IPR031642
DomainSHR-BD

VPS13A VPS13D

7.09e-0442052IPR009543
DomainVPS13_C

VPS13A VPS13D

7.09e-0442052PF16909
DomainVPS13_C

VPS13A VPS13D

7.09e-0442052IPR031645
DomainSHR-BD

VPS13A VPS13D

7.09e-0442052PF06650
DomainHEAT_type_2

TEX10 GCN1 SCYL3

7.91e-04172053IPR021133
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MAGI1 EPS15 MYCBP2 SLC30A4 TRRAP CHRM3 DNAH14 KMT2C GPR158 ARHGAP44 KCNN2 PIP5K1A ADGRD1 MCPH1 HECTD4 FRYL TEP1 C2CD2 SFXN1 PLEKHG4B WDR11 PRPF3 PKP3 ANKRD11 LRP1 LRP5 MACF1 QSER1 PNPLA7 CSMD1 CFAP69 PCDH1 RAI1

1.27e-1014892113328611215
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MTA2 ABCF1 MAN1A1 MAN2A2 MYCBP2 PIEZO1 CD109 MBOAT2 B3GAT3 DMXL1 GPR180 CIAPIN1 ERP29 UBIAD1 NAXE RUSF1 WDR62 SGSH GNPTAB GRN SLC4A2 ABCE1 LTN1 LRP1 LRP5 TMEM131 PRAF2 M6PR

1.23e-0912012112835696571
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

DLG5 MYCBP2 MED24 CCDC138 PIP5K1A PAK1IP1 PYCR2 APC DICER1 EPC1 LTN1 INTS9 QSER1

3.48e-092422111334011540
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MTA2 MAN2A2 MYCBP2 PPRC1 PIEZO1 TRRAP ZCCHC14 KMT2C SSH1 ARHGAP44 GCN1 DOCK3 FLII B4GALNT4 HECTD4 FRYL TEP1 C2CD2 PLCD3 NISCH ANKRD11 PDCD11 LRP5 ZFYVE26 RAI1 HR

4.19e-0911052112635748872
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EPS15 DLG5 ABCF1 MYCBP2 PIEZO1 TTLL5 DMXL1 SACS POP1 CCDC138 DHPS VPS13A PIP5K1A ERP29 PYCR2 WDR62 MYO18A FAM98A SIK3 DICER1 SLC4A2 DNAJA3 WDR11 NISCH ANKRD11 PDCD11 MACF1 TMEM131 M6PR

3.18e-0814872112933957083
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MTA2 DLG5 ABCF1 MYCBP2 TEX10 TRRAP SACS PAK1IP1 GCN1 MED16 ANXA2 HECTD4 MYO18A ZNF629 APC SIK3 LDHA OPA1 SFXN1 DNAJA3 PRPF3 GYS1 MACF1 PRAF2

5.24e-0810822112438697112
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TTLL5 DSCAML1 SEPTIN8 GPR158 GCN1 PCLO FRYL TMEM131

6.23e-0887211812465718
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

DCHS2 ABCF1 TEX10 TRRAP KMT2C SERPINA1 COPS6 FLII ANK1 PCDHB9 OPA1 VPS13D LOXHD1 IGHMBP2 ANKRD11 RAI1

7.64e-084972111636774506
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 DSCAML1 STAB1 ZCCHC14 KMT2C GPR158 GCN1 GNPTAB SIK3 DICER1 MACF1

1.49e-072252111112168954
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MTA2 ABCF1 MYCBP2 TEX10 TRRAP POP1 PAK1IP1 GCN1 FLII MED16 ANXA2 MYO18A ZNF629 FAM98A SFXN1 PRPF3 IGHMBP2 PDCD11 MACF1

2.28e-077592111935915203
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EPS15 DLG5 ABCF1 PIEZO1 TEX10 TRRAP B3GAT3 MED24 KMT2C CEPT1 POP1 PAK1IP1 MED16 APC ARHGEF12 FAM98A DICER1 PLCD3 MTA1 WDR11 IGHMBP2 LTN1 ANKRD11 PDCD11 MACF1 INTS9 EXOC2

4.63e-0714972112731527615
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MAGI1 TPR EPS15 MYCBP2 TEX10 SIRPG SSH1 GPR158 ARHGAP44 FLII HECTD4 APC ARHGEF12 SIK3 OPA1 NISCH LRP1 MACF1 QSER1 PRAF2 RAI1

4.96e-079632112128671696
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TPR ABCF1 MYCBP2 ADGRB1 SEPTIN8 GPR158 PYCR2 GCN1 SHISA6 DOCK3 FLII ANXA2 ANXA2P2 PCLO MYO18A APC LDHA OPA1 SFXN1 DNAJA3 ABCE1 IGHMBP2 MACF1

5.23e-0711392112336417873
Pubmed

Defining the membrane proteome of NK cells.

MTA2 EPS15 ABCF1 MAN1A1 MYCBP2 B3GAT3 ERP29 GCN1 RUSF1 MED16 ANXA2 MYO18A LDHA OPA1 SLC4A2 ORC2 WDR11 ABCE1 NISCH IGHMBP2 GYS1 EXOC2 M6PR

8.05e-0711682112319946888
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ABCF1 POP1 PIP5K1A ZNF629 APC SIK3 ANKRD50 DICER1 SLC4A2 PLCD3 WDR11 ABCE1 NISCH QSER1 PCDHGC3 HR

2.63e-066502111638777146
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DLG5 CCDC138 WDR62 APC ARHGEF12 DICER1 DENND4C VPS13D MACF1

5.80e-06209211936779422
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MTA2 TPR EPS15 ABCF1 MYCBP2 SEPTIN8 ERP29 PYCR2 COPS6 GCN1 NAXE FLII ANXA2 MYO18A GRN LDHA DNAJA3 MTA1 NISCH GYS1 MACF1

7.81e-0611492112135446349
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MTA2 TPR ABCF1 MYCBP2 TEX10 TRRAP POP1 ERP29 PYCR2 GCN1 FLII FAM98A LDHA SFXN1 PLCD3 DNAJA3 WDR11 PRPF3 ABCE1 LTN1 PDCD11 MACF1 EXOC2

9.16e-0613532112329467282
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SACS SHISA6 ANXA2 ANXA2P2 PCLO SIK3 OPA1 MACF1 PRAF2 PCDH1

9.44e-062812111028706196
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

MTA2 EPS15 TEX10 MED24 PIP5K1A COPS6 FLII OPA1 SFXN1 DNAJA3 MTA1 WDR11 LTN1 EXOC2

9.48e-065602111435241646
Pubmed

Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

PIEZO1 STAB1 SEPTIN8 GCN1 MYO18A TMEM131

1.19e-058321169039502
Pubmed

The functional interactome landscape of the human histone deacetylase family.

MTA2 TPR MYCBP2 SINHCAF GCN1 DICER1 DNAJA3 MTA1 ANKRD11 PDCD11

1.20e-052892111023752268
Pubmed

The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.

MTA2 ZFPM2 MTA1

1.21e-058211318067919
Pubmed

cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I).

GBP2 ANXA2 ANXA2P2

1.21e-05821133038891
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

MTA2 ABCF1 POP1 PYCR2 COPS6 GCN1 FLII GRN LDHA OPA1 SFXN1 WDR11 PRPF3 ABCE1 GYS1

1.23e-056532111533742100
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ADGRB1 PIDD1 DSCAML1 DNAH14 KMT2C POP1 VPS13A ANK1 MCPH1 PCLO GRN SLC25A16 SFXN1 LOXHD1 ABCE1 RAI1

1.25e-057362111629676528
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MTA2 IL12RB2 TRRAP DHPS WDR62 ZNF629 SIK3 TEP1 DICER1 OPA1 DNAJA3 MTA1 PRPF3 EPC1 LTN1 LRP1 MACF1 SIGLEC1 CSMD1 RAI1

1.72e-0511162112031753913
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ABCF1 MYCBP2 TEX10 TRRAP POP1 PAK1IP1 MED16 HECTD4 APC DICER1 PRPF3 NISCH

1.78e-054402111234244565
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAGI1 DLG5 MYCBP2 ZCCHC14 CCDC138 BICC1 WDR62 ZNF629 APC FRYL FAM98A SIK3 DENND4C VPS13D ANKRD11 MACF1 MUSK

2.27e-058612111736931259
Pubmed

The regulation and deregulation of Wnt signaling by PARK genes in health and disease.

LRRK2 APC LRP5

2.56e-0510211324115276
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

MTA2 EPS15 DLG5 ABCF1 CIAPIN1 PIP5K1A COPS6 GCN1 ANXA2 MYO18A FRYL FAM98A LDHA OPA1 PDLIM4 SFXN1 ABCE1 LRP1 PDCD11 PRAF2 M6PR MMUT

3.32e-0513672112232687490
Pubmed

Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.

ANXA2 ANXA2P2

3.66e-052211223148505
Pubmed

Muscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice.

CHRM3 APC

3.66e-052211221705482
Pubmed

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.

ANXA2 ANXA2P2

3.66e-05221123013423
Pubmed

Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.

ANXA2 ANXA2P2

3.66e-052211217549680
Pubmed

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.

ANXA2 ANXA2P2

3.66e-052211239384746
Pubmed

LPT1 encodes a membrane-bound O-acyltransferase involved in the acylation of lysophospholipids in the yeast Saccharomyces cerevisiae.

MBOAT1 MBOAT2

3.66e-052211217890783
Pubmed

Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.

ANXA2 ANXA2P2

3.66e-052211219841537
Pubmed

The mitochondrial protein hTID-1 partners with the caspase-cleaved adenomatous polyposis cell tumor suppressor to facilitate apoptosis.

APC DNAJA3

3.66e-052211219900451
Pubmed

Genetic heterogeneity in Leigh syndrome: Highlighting treatable and novel genetic causes.

NAXE VPS13D

3.66e-052211232020600
Pubmed

CFTR is a tumor suppressor gene in murine and human intestinal cancer.

CFTR APC

3.66e-052211226751771
Pubmed

Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.

ANXA2 ANXA2P2

3.66e-052211222185818
Pubmed

Protocadherins: a large family of cadherin-related molecules in central nervous system.

PCDH1 PCDHGC3

3.66e-05221128508762
Pubmed

A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.

ANXA2 ANXA2P2

3.66e-052211221486955
Pubmed

Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.

ANXA2 ANXA2P2

3.66e-052211219580511
Pubmed

GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations.

BICC1 PCLO

3.66e-052211226391493
Pubmed

Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.

ANXA2 ANXA2P2

3.66e-052211236739096
Pubmed

Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.

ANXA2 ANXA2P2

3.66e-052211222517898
Pubmed

Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.

ANXA2 ANXA2P2

3.66e-052211230462534
Pubmed

Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics.

OMA1 OPA1

3.66e-052211224550258
Pubmed

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

ANXA2 ANXA2P2

3.66e-052211221572519
Pubmed

ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.

ANXA2 ANXA2P2

3.66e-052211237832154
Pubmed

Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.

ANXA2 ANXA2P2

3.66e-052211230902828
Pubmed

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

ANXA2 ANXA2P2

3.66e-052211232687500
Pubmed

Autoantibodies against muscarinic type 3 receptor in Sjögren's syndrome inhibit aquaporin 5 trafficking.

CHRM3 AQP5

3.66e-052211223382834
Pubmed

Serpin A1 and CD91 as host instruments against HIV-1 infection: are extracellular antiviral peptides acting as intracellular messengers?

SERPINA1 LRP1

3.66e-052211217258834
Pubmed

Agents that bind annexin A2 suppress ocular neovascularization.

ANXA2 ANXA2P2

3.66e-052211220607799
Pubmed

Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1.

MAGI1 ADGRB1

3.66e-05221129647739
Pubmed

A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.

ANXA2 ANXA2P2

3.66e-052211231253864
Pubmed

Alpha 1-antitrypsin deficiency alleles in cystic fibrosis lung disease.

CFTR SERPINA1

3.66e-052211212689922
Pubmed

Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.

ANXA2 ANXA2P2

3.66e-052211219628708
Pubmed

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.

ANXA2 ANXA2P2

3.66e-052211220847146
Pubmed

Cellular chloride and bicarbonate retention alters intracellular pH regulation in Cftr KO crypt epithelium.

CFTR SLC4A2

3.66e-052211226542396
Pubmed

Low-density lipoprotein receptor-related protein 1 mediates α1-antitrypsin internalization in CD4+ T lymphocytes.

SERPINA1 LRP1

3.66e-052211226206901
Pubmed

Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.

ANXA2 ANXA2P2

3.66e-052211219536308
Pubmed

Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.

APC SLC15A1

3.66e-052211227458604
Pubmed

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

ANXA2 ANXA2P2

3.66e-052211238290972
Pubmed

Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.

ANXA2 ANXA2P2

3.66e-052211235064931
Pubmed

Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.

ANXA2 ANXA2P2

3.66e-052211228130864
Pubmed

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.

APC GUCY2C

3.66e-052211217681179
Pubmed

Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.

ANXA2 ANXA2P2

3.66e-052211220826156
Pubmed

Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.

ANXA2 ANXA2P2

3.66e-052211227468426
Pubmed

Effect of Alpha-1 Antitrypsin on CFTR Levels in Primary Human Airway Epithelial Cells Grown at the Air-Liquid-Interface.

CFTR SERPINA1

3.66e-052211233946490
Pubmed

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.

ANXA2 ANXA2P2

3.66e-052211227389701
Pubmed

PLEKHG4B enables actin cytoskeletal remodeling during epithelial cell-cell junction formation.

ANXA2 PLEKHG4B

3.66e-052211233310911
Pubmed

Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.

ANXA2 ANXA2P2

3.66e-052211217360942
Pubmed

Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.

ANXA2 ANXA2P2

3.66e-052211219587120
Pubmed

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.

ANXA2 ANXA2P2

3.66e-052211219022301
Pubmed

Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation.

CFTR AQP5

3.66e-052211217553491
Pubmed

Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.

ANXA2 ANXA2P2

3.66e-052211238253182
Pubmed

ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.

CFTR ERP29

3.66e-052211221525008
Pubmed

MTA1 coregulator regulates LDHA expression and function in breast cancer.

LDHA MTA1

3.66e-052211231570164
Pubmed

Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model.

APC GUCY2C

3.66e-052211215825168
Pubmed

Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).

CFTR CHRM3

3.66e-052211223760269
Pubmed

Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.

APC GUCY2C

3.66e-052211219351847
Pubmed

Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage.

OMA1 OPA1

3.66e-052211224719224
Pubmed

Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.

ANXA2 ANXA2P2

3.66e-052211221737841
Pubmed

AQP5, a second gene at play with CFTR in aquagenic palmoplantar keratoderma.

CFTR AQP5

3.66e-052211236645858
Pubmed

OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury.

OMA1 OPA1

3.66e-052211224671334
Pubmed

Melatonin Rescues Influenza A Virus-Induced Cellular Energy Exhaustion via OMA1-OPA1-S in Acute Exacerbation of COPD.

OMA1 OPA1

3.66e-052211239039850
Pubmed

Novel GUCY2C variant causing familial diarrhea in a Mennonite kindred and a potential therapeutic approach.

CFTR GUCY2C

3.66e-052211233949097
Pubmed

Overexpression of MTA1 inhibits the metastatic ability of ZR-75-30 cells in vitro by promoting MTA2 degradation.

MTA2 MTA1

3.66e-052211230642362
Pubmed

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice.

OMA1 OPA1

3.66e-052211222433842
Pubmed

Assignment of the metastasis-associated gene (Mta1) to mouse chromosome band 12F and the metastasis-associated gene 2 (Mta2) to mouse chromosome band 19B by fluorescence in situ hybridization.

MTA2 MTA1

3.66e-052211211856890
Pubmed

Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.

ANXA2 ANXA2P2

3.66e-052211238092984
Pubmed

Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.

ANXA2 ANXA2P2

3.66e-052211221788340
Pubmed

The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.

ANXA2 ANXA2P2

3.66e-052211227371724
Pubmed

Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.

ANXA2 ANXA2P2

3.66e-052211231817350
Pubmed

Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.

ANXA2 ANXA2P2

3.66e-052211224742684
Pubmed

Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.

ANXA2 ANXA2P2

3.66e-052211222453828
InteractionGOLGA1 interactions

DLG5 DMXL1 CCDC138 UBIAD1 SCYL3 APC ARHGEF12 DICER1 DENND4C WDR11 MACF1

2.99e-0618320611int:GOLGA1
GeneFamilyWD repeat domain containing

DPH7 EML6 WDR76 DMXL1 PAK1IP1 WDR62 MED16 TEP1 SEC31B WDR11 WDR87

9.99e-0626214711362
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

INSRR PLCZ1 UPRT ERN2 AQP6 WDR87 GYS2

1.46e-078421079417fffe0ba79f5851920258dcd0f6c09218be13
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 TTLL5 LRRK2 TEX10 SSH1 BICC1 DOCK3 ZFPM2 INTS9

2.87e-0718821096468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 TTLL5 LRRK2 TEX10 SSH1 BICC1 DOCK3 ZFPM2 INTS9

2.87e-0718821097a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 TTLL5 LRRK2 TEX10 SSH1 BICC1 DOCK3 ZFPM2 INTS9

2.87e-0718821099cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 INSRR KMT2C VPS13A PCLO FRYL NISCH ANKRD11 MACF1

3.90e-0719521097796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 INSRR KMT2C VPS13A PCLO FRYL NISCH ANKRD11 MACF1

3.90e-0719521093e519cffa6144a62b06124642a14c9ff39b76554
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat|Striatum / BrainAtlas - Mouse McCarroll V32

INSRR PLCZ1 ERN2 AQP6 WDR87 GYS2

1.60e-06762106041a8984b3ae4bb03ae6db8234c1333ac73098fa
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)|Striatum / BrainAtlas - Mouse McCarroll V32

INSRR PLCZ1 ERN2 AQP6 WDR87 GYS2

1.60e-067621063073a8ace46ad18bddd22ec8f3a1b59ee2fd989d
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)-|Striatum / BrainAtlas - Mouse McCarroll V32

INSRR PLCZ1 ERN2 AQP6 WDR87 GYS2

1.60e-067621063f5865b9cb6648b88eb873018e513c5efb457ae5
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

BCHE ISLR ADGRD1 BICC1 PKP3 LRP1 QSER1 SLC2A12

1.96e-06176210842541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPR GNPTAB APC ARHGEF12 HEATR5A VPS13D LTN1 TMEM131

2.95e-06186210803db813598b67b1e08f759758a1c2023396921fa
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

LRRK2 STAB1 SERPINA1 FES ANXA2 GRN LRP1 SIGLEC1

5.05e-062002108621af09aae34226902c03edf556562f3ab35a7d8
ToppCellCOVID_vent-Myeloid-Monocytic|COVID_vent / Disease condition, Lineage, Cell class and subclass

LRRK2 STAB1 SERPINA1 FES ANXA2 GRN LRP1 SIGLEC1

5.05e-062002108b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCellCOVID_vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

LRRK2 STAB1 SERPINA1 FES ANXA2 GRN LRP1 SIGLEC1

5.05e-062002108e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DLG5 INHA CHRM3 STAB1 SHISA6 ERN2 PNPLA7

5.59e-061442107013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

INSRR DSCAML1 SHISA6 PCDHB9 ZFPM2 LY6D CSMD1

6.99e-0614921076e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellmild-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

WDR76 MBOAT2 ZNF780B SCYL3 ORC2 GYS1

1.31e-0510921062f03d6ee8b13424cc6a5bc60ac3461b44dff9d79
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INHA PIP5K1A STRA6 SHISA6 DOCK3 ZFPM2 PDLIM4

1.47e-0516721071adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INHA PIP5K1A STRA6 SHISA6 DOCK3 ZFPM2 PDLIM4

1.47e-051672107743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE2 STRADB GPR158 NIPA1 ANK1 HECTD4 ARHGEF12

1.53e-05168210708fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE2 STRADB GPR158 NIPA1 ANK1 HECTD4 ARHGEF12

1.53e-051682107d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE4 ABCA9 ANK1 SGSH ZNF629 TEP1 WDR11

1.59e-0516921075f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCHS2 ADGRB1 ADGRD1 HECTD4 ANKRD50 LRP1 CDH6

1.65e-0517021075570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPH7 PIDD1 WDR76 UBIAD1 MCPH1 PKP3 ZFYVE26

1.92e-0517421077565f6d1c743809807d248ab0e098a2474d9c5b9
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSRR GPR158 GLP1R PCLO FRYL DENND4C SLC2A12

1.92e-051742107f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

NXPE4 NXPE2 CHRM3 SERPINA1 ERN2 AQP5 SERPINA11

2.22e-051782107f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

DCHS2 CFTR STRA6 SHISA6 ERN2 AQP5 PLEKHG4B

2.30e-0517921071fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 MBOAT1 CFTR INSRR MBOAT2 SACS SIK3

2.38e-051802107cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 CEPT1 ADGRD1 BICC1 PDLIM4 PCDHGC3 MUSK

2.47e-051812107e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 CEPT1 ADGRD1 BICC1 PDLIM4 PCDHGC3 MUSK

2.47e-05181210735eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

LRRK2 ALDH8A1 DSCAML1 SERPINA1 VPS13A BICC1 CDH6

2.74e-05184210751ed1ebfdef45149541917c66cbacad87072e51f
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL5 EML6 STAB1 WDR62 REXO5 PDLIM4 ORC2

2.84e-0518521076a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL5 EML6 STAB1 WDR62 REXO5 PDLIM4 ORC2

2.84e-05185210764791056cdbb739136dbef08f4b16e2b5427faad
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTLL5 INSRR CD109 ISLR PLAGL1 ADGRD1 BICC1

2.84e-0518521071b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD109 GBP2 NPHS1 ANXA2 GNPTAB GRN PDLIM4

2.84e-0518521075ed49b6d8214c6119355a6d3ee4e25d40bcc0c53
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRRK2 STAB1 KMT2C FAM186A PCLO LRP1 CSMD1

2.94e-05186210723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRB1 MBOAT2 ABCA9 NIPA1 PDLIM4 GALNT17 CSMD1

3.04e-0518721076f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

MAGI1 DLG5 CFTR INSRR MBOAT2 SACS GALNT17

3.04e-051872107ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 MBOAT1 CFTR BCHE BICC1 ANXA2 PLCD3

3.15e-051882107842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 MBOAT1 CFTR BCHE BICC1 ANXA2 PLCD3

3.15e-051882107a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD109 STAB1 SGSH GRN TEP1 C2CD2 IGHMBP2

3.37e-05190210763018acb7ad80415e861643162abdc2e55968ee4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 EML6 LRRK2 DSCAML1 DNAH14 BICC1 DOCK3

3.48e-051912107d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRD1 BICC1 DOCK3 ZFPM2 GALNT17 LRP1 CDH6

3.48e-05191210714057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACE CHRM3 MBOAT2 KCNN2 ARHGEF12 ZFPM2 PCDH1

3.48e-051912107f229abf69a1217194f74b0502486907e07dba989
ToppCell18-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

CFTR MFSD6L SERPINA1 SFTA2 ANXA2 AQP5 PKP3

3.60e-0519221079fae988ecd2ef1231bfd42a678a4903517694cbe
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFTR LRRK2 CHRM3 DNAH14 DUOX1 ARHGAP44 PCLO

3.60e-051922107cc9911e182a289779a2612bc213daae5607689e7
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINA1 SFTA2 ANXA2 LDHA AQP5 LY6D PKP3

3.60e-051922107612be3f861bd2f71a31c57f48c8b10930c3471ea
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINA1 SFTA2 ANXA2 LDHA AQP5 LY6D PKP3

3.60e-051922107f627a3f43e2340c8ba502211940171f25c7ff436
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRK2 STAB1 SERPINA1 FES GRN LRP1 SIGLEC1

3.72e-0519321074fb020f11fd7aff06952bfeaabc79b2c7b8873f6
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRRK2 STAB1 SERPINA1 FES GRN LRP1 SIGLEC1

3.84e-051942107885355ebe98e974f841cc59dce3b5228c642c5d0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EML6 CHRM3 GPR158 ARHGAP44 PCLO GALNT17 CSMD1

4.10e-051962107676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD109 ADAM8 STAB1 SERPINA1 ANXA2 GRN LDHA

4.10e-051962107a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.37e-051982107d347462ba6cb1c5a59c86dffbbe914cbc1e9cf16
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.37e-051982107c5a22846bccff948f90bc1d5fe309907dcd08348
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.37e-051982107c49c71b34151d82b8795763bcb633c301c35f659
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MBOAT1 CFTR STRA6 SHISA6 ERN2 AQP5 PLEKHG4B

4.37e-051982107af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.37e-0519821074780f0276546962a2fc9f1041cfe49d2919d72b2
ToppCellCOVID-19_Mild-Myeloid-Classical_Monocyte|COVID-19_Mild / Disease group, lineage and cell class

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.37e-051982107e78d027a095473af555762a4d542a73f5bb2e166
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EML6 CHRM3 GPR158 ARHGAP44 PCLO GALNT17 CSMD1

4.37e-0519821076d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EML6 CHRM3 GPR158 ARHGAP44 PCLO GALNT17 CSMD1

4.37e-0519821074ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell3'_v3-lymph-node_spleen-Myeloid_Monocytic-Classical_monocytes|lymph-node_spleen / Manually curated celltypes from each tissue

LRRK2 STAB1 SERPINA1 FES ANXA2 GRN LRP1

4.37e-051982107187a04d498f0b355cb11c81172721698818082d6
ToppCellCOVID-19_Severe-Classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.37e-051982107b88c4c0ed1abf0a28dbe05b04b9bee1073855ba8
ToppCell3'_v3-lymph-node_spleen-Myeloid_Monocytic|lymph-node_spleen / Manually curated celltypes from each tissue

LRRK2 STAB1 SERPINA1 FES ANXA2 GRN LRP1

4.37e-051982107065c8a9655d19f93dfdb453c78bbfe7d857caf3e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRRK2 SERPINA1 FES ANXA2 GRN LRP1 SIGLEC1

4.52e-051992107cd93e8947bcf3c2d7e6d5bfd70300145fba15f74
ToppCellSkin|World / Skin and Kidney Cells in Lupus Nephritis Patients.

MYCBP2 DUOX1 ANXA2 LDHA LY6D PKP3 HR

4.52e-0519921076be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRRK2 STAB1 SERPINA1 FES ANXA2 GRN LRP1

4.52e-051992107571accef38f5b03a7e032495d5c6d25d27073428
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PIEZO1 SPOCD1 SLC4A2 PDLIM4 LOXHD1 GYS1 LRP1

4.52e-05199210785bb28369e0568b7b3bda095722102fc793f60ef
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 SERPINA1 BICC1 SFTA2 ANXA2 LDHA PDLIM4

4.52e-0519921072e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCellmild-immature_Neutrophil|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

WDR76 MBOAT2 ZNF780B SCYL3 GYS1

4.56e-05832105f7225bc24ad6df3a41375cc4614af824e0db3559
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 CHRM3 ANXA2 PCLO ERN2 AQP5 LRP5

4.66e-052002107d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

MYCBP2 EML6 CHRM3 ARHGAP44 PCLO GALNT17 CSMD1

4.66e-05200210748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TPR MYCBP2 KMT2C FRYL ANKRD11 MACF1 SIGLEC1

4.66e-05200210712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRRK2 SERPINA1 FES ANXA2 GRN LRP1 SIGLEC1

4.66e-052002107933db31e61e08ccf31105b3d3cf85c8d42c8174d
ToppCellCOVID_non-vent-Myeloid-Monocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.66e-0520021074243a9d32f3a11141284d0d944cb81194b532876
ToppCellCOVID-19-COVID-19_Mild-Myeloid-CD14+_Monocyte|COVID-19_Mild / Disease, condition lineage and cell class

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.66e-052002107f76d3647f8ab5f7be018b0697c911597198e03f5
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.66e-052002107465ed50e0b92bb8c27ffe56d816f063a45b52be9
ToppCellInfluenza-Influenza_Severe-Myeloid-CD14+_Monocyte|Influenza_Severe / Disease, condition lineage and cell class

LRRK2 STAB1 SERPINA1 FES ANXA2 GRN LRP1

4.66e-0520021077add63fb6235ddb928aa9482a1dd9d62638bb3d9
ToppCellCOVID_non-vent|World / Disease condition, Lineage, Cell class and subclass

LRRK2 STAB1 SERPINA1 ANXA2 GRN LRP1 SIGLEC1

4.66e-052002107accef1050963dc91e189ac3d38228f15bf57e06e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL36B LRRK2 DSCAML1 SERPINA1 GLP1R CDH6

4.96e-051382106a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Cadm2_(Striatum,_Cadm_state_SPNs)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PDE6C ALDH8A1 ADGRD1 SFTA2

5.41e-054421043cfa4da7895eb7c8e3da7ec56234fc3b9e70d9ea
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Cadm2_(Striatum,_Cadm_state_SPNs)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PDE6C ALDH8A1 ADGRD1 SFTA2

5.41e-0544210414dd140cbcc04af35a22fbe70019cba9c5a4ee09
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Cadm2_(Striatum,_Cadm_state_SPNs)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PDE6C ALDH8A1 ADGRD1 SFTA2

5.41e-0544210406a884bf4dc74bb30e62005e4813396695844122
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 DLG5 MBOAT1 CFTR INSRR MBOAT2

6.78e-051462106ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI1 EML6 ZNF607 AQP6 GALNT17 LOXHD1

6.78e-051462106e887e9de895fd453faa703997ef372cc6410fc49
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRD1 SHISA6 GNPTAB UPRT HEATR5A AQP5

8.78e-0515321065501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Scn4b_(Globus_Pallidus_Externus_(GP),_"Prototypical")|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MOAP1 DUOX1 LY6D SUN5

9.71e-0551210491e17b1a85e2b5c507c64f39f322a5a9b7bf30bd
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Scn4b_(Globus_Pallidus_Externus_(GP),_"Prototypical")--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MOAP1 DUOX1 LY6D SUN5

9.71e-0551210474d7932d0e7363c00117890747980b4b04ff4524
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Scn4b_(Globus_Pallidus_Externus_(GP),_"Prototypical")-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MOAP1 DUOX1 LY6D SUN5

9.71e-0551210488597bef58fe807b65da34925e863e7fbe3a7e3e
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

MYCBP2 IL36B CD109 LY6D VPS13D LRP1

9.77e-051562106ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCellfacs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TARM1 NXPE4 LRRK2 ADAM8 FOXD4 ANXA2

1.01e-0415721069d4308312301cb922f156a7b6aededc9e1c62807
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

CHRM3 STAB1 WDR62 HECTD4 SEC31B GSTCD

1.09e-04159210624f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SIGLEC8 ACE STAB1 TP53TG5 SLC4A2 PLEKHG4B

1.12e-041602106c61869d9dbba250270e59366e15af204e5b4395d
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LDHD ANK1 ARHGEF12 PLCD3 LRP1 SIGLEC1

1.16e-04161210660f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellfacs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSRR NXPE2 MBOAT2 SEPTIN8 ANK1 C2CD2

1.20e-041622106860ebf2390b4ad86475ad54717cbefcf61cd3b2a
ToppCellfacs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSRR NXPE2 MBOAT2 SEPTIN8 ANK1 C2CD2

1.20e-04162210614e9f8aaba308619eb9da90796c336e76cedac1f
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHA BCHE GPR149 STRA6 GUCY2C SIGLEC1

1.24e-0416321061eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BCHE BICC1 DOCK3 ZFPM2 GALNT17 CDH6

1.29e-041642106e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellfacs-Marrow-B-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NXPE2 GPR158 NIPA1 ANK1 HECTD4 ARHGEF12

1.29e-04164210618eeda51e69722992c3a7f699be293535a90868b
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL5 ADAM8 DSCAML1 SINHCAF ANK1 PLCD3

1.29e-04164210678de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK|Cerebellum / BrainAtlas - Mouse McCarroll V32

NXPE4 PIEZO1 BCHE NXPE2 SINHCAF STRA6

1.33e-0416521067d319a112b9062efee428bef6f4534d2ce782e04
DrugFosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A

PDE6C PIDD1 ADAM8 ZCCHC14 VPS13A PLAGL1 STRA6 MED16 ERN2 LY6D HR

2.11e-06197208114823_DN
Diseaselysosomal protective protein measurement

GNPTAB ZFPM2 M6PR

1.10e-0572033EFO_0008215
Diseaseautosomal recessive intellectual developmental disorder (is_implicated_in)

TPR WDR11

4.71e-0522032DOID:0060308 (is_implicated_in)
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CFTR ACE SLC4A2

5.08e-05112033DOID:0110861 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

OMA1 CFTR CD109 ISLR DSCAML1 ABCA9 KMT2C SACS VPS13A APC SFXN1 GUCY2C ABCE1 LRP1 HR

1.14e-0470220315C0009402
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13A VPS13D

1.41e-0432032DOID:0111611 (implicated_via_orthology)
DiseaseDiaphragmatic Hernia

CFTR STRA6 AQP5 ZFPM2

1.80e-04412034C0019284
Diseasetestosterone measurement

MAGI1 DCHS2 WDR76 GPR180 SERPINA1 FAM186A PLAGL1 SPOCD1 DOCK3 SFTA2 ANXA2 ZNF629 MFSD9 C2CD2 ZFPM2 WDR11 NISCH GYS1 LRP5 MACF1 RAI1

2.04e-04127520321EFO_0004908
Diseaset-cell surface glycoprotein CD8 beta chain measurement

BCHE MED16

2.80e-0442032EFO_0803135
DiseaseLafora disease (implicated_via_orthology)

GYS1 GYS2

2.80e-0442032DOID:3534 (implicated_via_orthology)
Diseaserho-related GTP-binding protein Rho6 measurement

BCHE SERPINA1

2.80e-0442032EFO_0803022
Diseasevenous thromboembolism, response to surgery

SFXN1 CSMD1

2.80e-0442032EFO_0004286, EFO_0009951
Diseaseintegrin alpha-5 measurement

BCHE MED16

2.80e-0442032EFO_0802637
DiseaseSmith-Magenis syndrome

FLII RAI1

2.80e-0442032C0795864
Diseaseprotocadherin beta-1 measurement

BCHE MED16

2.80e-0442032EFO_0802972
Diseasehistone acetyltransferase type b catalytic subunit measurement

BCHE MED16

2.80e-0442032EFO_0020452
DiseaseAutosomal Recessive Primary Microcephaly

PYCR2 WDR62 MCPH1

4.49e-04222033C3711387
Diseaseneuroimaging measurement

MAGI1 OMA1 DCHS2 SERPINA1 MCPH1 APC ARHGEF12 FRYL FAM98A SLC25A16 DENND4C DNAJA3 PRPF3 MACF1 QSER1 EXOC2 MUSK RAI1

4.54e-04106920318EFO_0004346
DiseaseN-acetylglucosaminylasparagine measurement

SERPINA1 GNPTAB

4.65e-0452032EFO_0800151
Diseaseaugurin measurement

BCHE MED16

4.65e-0452032EFO_0801399
DiseaseCholedochal Cyst, Type I

CFTR SLC4A2

4.65e-0452032C0009439
DiseaseCholedochal Cyst, Type II

CFTR SLC4A2

4.65e-0452032C1257796
DiseaseCholedochal Cyst, Type III

CFTR SLC4A2

4.65e-0452032C1257797
DiseaseCholedochal Cyst, Type IV

CFTR SLC4A2

4.65e-0452032C1257798
DiseaseCholedochal Cyst, Type V

CFTR SLC4A2

4.65e-0452032C1257799
DiseaseCholedochal Cyst

CFTR SLC4A2

4.65e-0452032C0008340
DiseaseC-type lectin domain family 4 member D measurement

BCHE MED16

4.65e-0452032EFO_0802347
Diseaseadenylyltransferase and sulfurtransferase MOCS3 measurement

BCHE MED16

4.65e-0452032EFO_0802257
Diseaseficolin-2 measurement

NXPE4 NXPE1

4.65e-0452032EFO_0008135
Diseaseuncharacterized protein C3orf18 measurement

BCHE MED16

4.65e-0452032EFO_0802193
DiseaseSUN domain-containing protein 3 measurement

NXPE4 NXPE1

4.65e-0452032EFO_0802102
Diseasev-set and transmembrane domain-containing protein 4 measurement

BCHE MED16

6.94e-0462032EFO_0803247
Diseaseprimary progressive multiple sclerosis (is_marker_for)

BCHE GRN

6.94e-0462032DOID:0050784 (is_marker_for)
Diseaseglucagon measurement, glucose tolerance test

SERPINA1 MACF1

6.94e-0462032EFO_0004307, EFO_0008463
Diseasepeptidyl-prolyl cis-trans isomerase-like 2 measurement

BCHE MED16

6.94e-0462032EFO_0801877
Diseasediabetes mellitus (implicated_via_orthology)

CFTR INSRR LRP1

7.42e-04262033DOID:9351 (implicated_via_orthology)
DiseaseLiver carcinoma

WDR76 ACE KMT2C SERPINA1 GPR158 KCNN2 ERP29 WDR62 APC GYS2 CSMD1

8.27e-0450720311C2239176
DiseaseGlycogen Storage Disease

LDHA GYS1 GYS2

8.31e-04272033C0017919
Diseaseapolipoprotein A 1 measurement

XIRP1 MAN2A2 ABCA9 STAB1 GPR180 MED24 GPR149 FES SIK3 ZFPM2 WDR11 LRP1 MACF1 M6PR MUSK

8.31e-0484820315EFO_0004614
Diseasepancreatic ductal carcinoma (is_marker_for)

ACE ADAM8 SERPINA1 ANXA2

8.35e-04612034DOID:3587 (is_marker_for)
Diseasechronic obstructive pulmonary disease (is_implicated_in)

CFTR ACE CHRM3 SERPINA1

9.43e-04632034DOID:3083 (is_implicated_in)
Diseasebaculoviral IAP repeat-containing protein 5 measurement

BCHE MED16

9.67e-0472032EFO_0020174
DiseaseC-C motif chemokine 1 measurement

BCHE MED16

9.67e-0472032EFO_0008041
Diseaseuroplakin-3b-like protein measurement

BCHE MED16

9.67e-0472032EFO_0802204
Diseaseimmunoglobulin superfamily containing leucine-rich repeat protein 2 measurement

ISLR STRA6

9.67e-0472032EFO_0021879
Diseaseglutathione S-transferase A4 measurement

BCHE MED16

9.67e-0472032EFO_0801637
DiseaseIntellectual Disability

TRRAP KMT2C SACS DHPS STRA6 PYCR2 WDR62 APC MACF1 RAI1

1.13e-0344720310C3714756
Diseaseproteinuria (implicated_via_orthology)

ACE NPHS1 HR

1.14e-03302033DOID:576 (implicated_via_orthology)
Diseasedesmoglein-1 measurement

BCHE MED16

1.28e-0382032EFO_0020321
Diseasealpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 measurement

BCHE MED16

1.28e-0382032EFO_0801373
Diseasechromobox protein homolog 5 measurement

BCHE MED16

1.28e-0382032EFO_0020258
Diseasetumor necrosis factor receptor superfamily member 3 measurement

BCHE MED16

1.28e-0382032EFO_0020813
Diseaseprotein sel-1 homolog 2 measurement

BCHE MED16

1.28e-0382032EFO_0801962
Diseasekallistatin measurement

SERPINA1 SERPINA11

1.28e-0382032EFO_0008196
Diseasecerebellar ataxia (implicated_via_orthology)

VPS13A PNPLA7

1.28e-0382032DOID:0050753 (implicated_via_orthology)
Diseasecathepsin S measurement

GNPTAB M6PR

1.28e-0382032EFO_0008073
Diseasekallikrein-6 measurement

BCHE MED16

1.28e-0382032EFO_0801739
DiseasePH and SEC7 domain-containing protein 1 measurement

SERPINA1 MED16

1.28e-0382032EFO_0803302
Diseasecolorectal adenoma

OMA1 SSH1 C2CD2

1.50e-03332033EFO_0005406
Diseasestomach cancer (is_implicated_in)

ACE KMT2C APC TEP1

1.55e-03722034DOID:10534 (is_implicated_in)
Diseasetriglyceride measurement, response to selective serotonin reuptake inhibitor

IL12RB2 PCDH1 CDH6

1.64e-03342033EFO_0004530, EFO_0005658
Diseaseepididymal-specific lipocalin-10 measurement

BCHE MED16

1.64e-0392032EFO_0801576
Diseasecyclin-dependent kinase 5:cyclin-dependent kinase 5 activator 1 complex measurement

BCHE MED16

1.64e-0392032EFO_0020296
DiseaseAutosomal Recessive Polycystic Kidney Disease

CFTR SLC4A2

1.64e-0392032C0085548
Diseaseendothelin-converting enzyme 1 measurement

BCHE MED16

1.64e-0392032EFO_0008121
Diseasemast cell-expressed membrane protein 1 measurement

BCHE MED16

1.64e-0392032EFO_0801787
Diseaseinterleukin-34 measurement

BCHE MED16

1.64e-0392032EFO_0020505
DiseaseRenal Cell Carcinoma

LRRK2 PIDD1 BCHE DNHD1 M6PR

1.96e-031282035C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

LRRK2 PIDD1 BCHE DNHD1 M6PR

1.96e-031282035C1266043
DiseaseChromophobe Renal Cell Carcinoma

LRRK2 PIDD1 BCHE DNHD1 M6PR

1.96e-031282035C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

LRRK2 PIDD1 BCHE DNHD1 M6PR

1.96e-031282035C1266044
DiseasePapillary Renal Cell Carcinoma

LRRK2 PIDD1 BCHE DNHD1 M6PR

1.96e-031282035C1306837
Diseaseaxin-2 measurement

BCHE MED16

2.04e-03102032EFO_0801400
Diseasetropomyosin beta chain measurement

BCHE MED16

2.04e-03102032EFO_0020787
Diseaseinterleukin-37 measurement

BCHE MED16

2.04e-03102032EFO_0020506
Diseaseinsulin growth factor-like family member 3 measurement

BCHE MED16

2.04e-03102032EFO_0801700
Diseasephosphatidylethanolamine ether measurement

GALNT17 MUSK

2.04e-03102032EFO_0010229
Diseasestromal interaction molecule 1 measurement

BCHE MED16

2.04e-03102032EFO_0802093
DiseasePR domain zinc finger protein 1 measurement

BCHE MED16

2.49e-03112032EFO_0801904
Diseasephosphatidylcholine 32:0 measurement

MAN1A1 MUSK

2.49e-03112032EFO_0010372
Diseaseinterleukin-10 receptor subunit alpha measurement

BCHE MED16

2.49e-03112032EFO_0021890
Diseaseinvasive ductal carcinoma (is_marker_for)

INHA ADGRB1 ANXA2

2.63e-03402033DOID:3008 (is_marker_for)
DiseaseInherited neuropathies

SACS NIPA1 ZFYVE26

2.63e-03402033C0598589
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

SERPINA1 GRN

2.97e-03122032EFO_0801493
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

ZFPM2 LRP1

2.97e-03122032DOID:3827 (implicated_via_orthology)
Diseaseoncostatin-M measurement

BCHE MED16

2.97e-03122032EFO_0010792
Diseasetyrosine-protein kinase ZAP-70 measurement

BCHE MED16

2.97e-03122032EFO_0020833
Diseaseniacinamide measurement

SEPTIN8 EXOC2

2.97e-03122032EFO_0010511
DiseaseColorectal Neoplasms

CFTR CD109 ABCA9 APC SFXN1 GUCY2C ABCE1

3.18e-032772037C0009404
Diseasehemoglobin A1 measurement

DLG5 PIEZO1 WDR76 SERPINA1 SINHCAF GLP1R VPS13A ANK1 MACF1 MUSK

3.38e-0352020310EFO_0007629
Diseaseschizophrenia (is_marker_for)

BCHE ACE OPA1

3.45e-03442033DOID:5419 (is_marker_for)
Diseasekallikrein-12 measurement

BCHE MED16

3.49e-03132032EFO_0008194
Diseaseximenoylcarnitine (C26:1) measurement

IGHMBP2 LRP5

3.49e-03132032EFO_0800543
Diseaseprostate carcinoma (is_implicated_in)

INHA E2F5

3.49e-03132032DOID:10286 (is_implicated_in)
DiseaseDisorder of eye

PDE6C STRA6 GRN OPA1 PRPF3 LRP5

3.59e-032122036C0015397
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

LRRK2 PIDD1 BCHE DNHD1 M6PR

3.67e-031482035C0279702
Diseasecoronary artery disease

OMA1 CFTR CD109 DMXL1 SERPINA1 SINHCAF GPR149 FES BICC1 HECTD4 ARHGEF12 ANKRD50 ZFPM2 SLC15A1 LRP1 SLC2A12 RAI1

3.83e-03119420317EFO_0001645
Diseasehomocysteine measurement

DCHS2 CSMD1 MMUT

3.92e-03462033EFO_0004578
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

BICC1 LRP5

4.06e-03142032DOID:898 (implicated_via_orthology)
Diseasebody weights and measures, parental genotype effect measurement

CHRM3 FES

4.06e-03142032EFO_0004324, EFO_0005939
Diseaselevel of Phosphatidylethanolamine (18:1_18:1) in blood serum

SIK3 MUSK

4.06e-03142032OBA_2045142

Protein segments in the cluster

PeptideGeneStartEntry
HIPRTLSAVPSSALK

EPC1

776

Q9H2F5
TLLLLLTGKLTPTHG

ABCF1

666

Q8NE71
GKPHVASLSFRSLLE

SLC4A2

361

P04920
AASGLLFTHLVVLTP

B3GAT3

126

O94766
STLLGHISLFSGLLP

BPIFB3

161

P59826
DPLVSIGALISKAHL

ALDH8A1

321

Q9H2A2
LLSPGSHSLFTRAIL

BCHE

236

P06276
SPSIHTLTEVLKGVL

ERVK-19

446

O71037
LRLSAHTILPGSKTR

ANKRD11

426

Q6UB99
EGRSPIFTHLVTSLK

CFTR

1046

P13569
PEVTSAHFAGSLLLL

CATSPERD

96

Q86XM0
VARLTGSVLPHTIKA

CSMD1

996

Q96PZ7
TGSVSVALHPLVILN

COPS6

36

Q7L5N1
LSVSTPEHLHKIGLL

ACE

426

P12821
AAIGKHALLSSTLPS

ADGRD1

246

Q6QNK2
TDNLVLSIHKLPASG

ADGRB1

766

O14514
LSIHKLPASGATDIS

ADGRB1

771

O14514
DPLTHLLVINKTGST

ABCA9

911

Q8IUA7
RSASLHLPKLSITGT

SERPINA1

306

P01009
HTDIVTLLLKNGASP

ANK1

746

P16157
SGLHTKGALPLDTVT

ERP29

31

P30040
ATTDLLTKLPAHTVG

GRN

266

P28799
LPIATIFTTHATLLG

GYS2

196

P54840
SIVLKLPGHSTILNS

CHRM3

366

P20309
DIILSGLVPGSTTLH

CIAPIN1

61

Q6FI81
LSGHLETVILGLLKT

ANXA2

91

P07355
VPASKGHASVVSLLI

ANKRD50

721

Q9ULJ7
VALLVPSGVDLTTLH

DNHD1

2941

Q96M86
PSGVDLTTLHRLLAL

DNHD1

2946

Q96M86
AKSAHLAGLLLRSPT

DNHD1

3531

Q96M86
AKLLTEVHAASGSLP

ADAM8

641

P78325
LLSESPGKLHVEVSA

DICER1

1156

Q9UPY3
LSGHLETVILGLLKT

ANXA2P2

91

A6NMY6
LLEHLAGSLASAIPV

BICC1

271

Q9H694
VEIISIKPSAGHLSS

DMXL1

961

Q9Y485
LGLESTLISSKPQSH

ARHGEF12

1181

Q9NZN5
PALSIGLSVTLGHLV

AQP5

161

P55064
GTLKSVGLSHAPTLL

SLC25A16

211

P16260
HLGPVVSKALSTSCL

RAI1

1671

Q7Z5J4
SLPATHIRGKCSVTL

MTA2

96

O94776
GILSHHDPLLQIKTS

QSER1

91

Q2KHR3
TGLPLRIHVSGSTIA

GUCY2C

956

P25092
IKPGISLATVSAVLH

INTS9

531

Q9NV88
TIPATLLVDHVGSKT

SLC2A12

331

Q8TD20
LISVSGSDILIPHLL

OR5D14

186

Q8NGL3
VAGVSLKTLHPDLGT

LDHA

206

P00338
FSQGIHSLLLPILVT

LTN1

1311

O94822
SVVKAELLPSGVTHL

DUOX1

1276

Q9NRD9
GLKVVSLTPHSVGLE

NPHS1

946

O60500
ATLKAPLRVHITSLL

PAEP

51

P09466
HSILSVLKGLTVPIA

NAXE

201

Q8NCW5
LHGELSSLPSLRAIV

FLII

71

Q13045
RSGLISVAITLHPTA

KMT2C

4076

Q8NEZ4
PVSGKVITTDALHSL

MAGI1

196

Q96QZ7
RLSPTLSSTKGHLLI

MCPH1

331

Q8NEM0
ETTTHVLSGKPLRTL

MCPH1

681

Q8NEM0
GLSLLFHLTICTTLP

MBOAT2

241

Q6ZWT7
HKSILPNSLGVSERL

GNPTAB

771

Q3T906
LLSLHVKSLGASPTV

MFSD9

66

Q8NBP5
PAGIFKHTLSISRAL

MFSD9

141

Q8NBP5
KSTLTLIPLLGTHEV

GLP1R

351

P43220
TVTIGLLLIPKFSHS

GPR158

656

Q5T848
TLIGSIHALPGLISQ

KCNN2

516

Q9H2S1
TGTNKTLLISTLHRP

LRP1

3261

Q07954
AALLLGTLSPQVHTL

ERN2

21

Q76MJ5
FPGIVSKHLETSLTI

ZFPM2

791

Q8WW38
KVVEGSLTHPFALTL

LRP5

231

O75197
GDVTVKPSHVILLGS

IL12RB2

31

Q99665
LAVLLSPLSRVSVGH

LOXHD1

351

Q8IVV2
PDSRLSTGLAKHLLS

HR

546

O43593
RDVTASLLPVLKSSH

FAM90A27P

201

A6NNH2
LAEGTFTPLTALSHL

ISLR

161

O14498
TTSQALLHPVTSGLK

MFSD6L

181

Q8IWD5
PHLILLASTTVLVGA

MFSD6L

366

Q8IWD5
LVGLTAETSHALVPK

MOAP1

66

Q96BY2
SLGTPAHAVTLAITK

PCLO

2856

Q9Y6V0
HSLVKLTRGALLPLS

EXOC2

511

Q96KP1
TSHKLLTPQTRLGET

PCDH1

721

Q08174
IPIKVASGSDLHLTD

MYO18A

66

Q92614
KSTSPLARLHGSSIL

PDE6C

616

P51160
RLSPSILESFIHLTG

FRYL

736

O94915
SLGGKVVTPLHINLS

DLG5

711

Q8TDM6
LTTPAVSLSLAKHLG

LMLN2

351

A0A1B0GTW7
GPSVATLHKALTLTL

LMLN2

686

A0A1B0GTW7
IGTGHLLAKILVSSL

LRRK2

621

Q5S007
ILSHSNVKTLSGGIP

GBP2

271

P32456
LGTLVSHVTLRLLKP

GCN1

916

Q92616
SAHGVKLVLPSLLAA

GCN1

1491

Q92616
LSSVTLPLTISSGHK

GPR180

421

Q86V85
TPALSASLPIHIKVL

PCDHGC3

221

Q9UN70
LSRSHIGKAILSQPA

HECTD4

1391

Q9Y4D8
ALVGPTAHSRLLVIS

HECTD4

2966

Q9Y4D8
AILQSPHKRLTLSGI

FOXD4

116

Q12950
LGITHTVGSLSTKPE

PIP5K1A

91

Q99755
EHALSAIGPTLLLTS

PNPLA7

751

Q6ZV29
AISRGIVPSHTAVKL

MACF1

2316

Q9UPN3
IDSHGKLSVLRLSPS

MED16

446

Q9Y2X0
LIHPSFGTLVTVSRL

DCHS2

1561

Q6V1P9
GTVSLHAPTGKTLSL

GPR149

556

Q86SP6
TLHSLAVLVSLLGPE

SCYL3

396

Q8IZE3
GPLSHSILTEAIKAA

POP1

436

Q99575
GSLPLQKLHLVSRSI

OPA1

26

O60313
ISPKSTGSVRQLLHE

ABCE1

416

P61221
LGVISKTFQLSSHPI

CD109

186

Q6YHK3
VLSPFLHIGSVITLA

CEPT1

286

Q9Y6K0
LLTPIIPSKHALDSA

CEFIP

446

Q711Q0
AAPLSRSIKPVTLHL

IL36B

31

Q9NZH7
STGLLDSILSVILHP

HEATR5A

441

Q86XA9
LKHLAGSASPSVVLI

C2CD2

216

Q9Y426
PVILSHLRISSKGLL

CCDC138

536

Q96M89
SGPIHVLLINKESSS

E2F5

221

Q15329
IERTTLTLTHSLPGI

DOCK3

1476

Q8IZD9
PLKIISSDSTGQLHL

DPH7

161

Q9BTV6
TLAFLVGSHISLPRA

AQP6

86

Q13520
ARHLTLDPASKSLGL

DSCAML1

1941

Q8TD84
AGALAAVLKHSSTLP

DHPS

11

P49366
TLGLITATTLRLHPA

LDHD

251

Q86WU2
GLPLVLLSTHKTLLD

GPAT2

196

Q6NUI2
SKILLHSLRPAVLTG

DENND4C

416

Q5VZ89
HLGALGTTTLLPDTR

GALNT17

511

Q6IS24
PLILIQTHGSASIKD

DNAH14

3061

Q0VDD8
PTRTALAHSALSLGL

LY6D

101

Q14210
SPTGAVIHKLGITLV

MBOAT1

236

Q6ZNC8
TLPSAETALILHRKG

MAN2A2

1066

P49641
SKLLSGVLFHSSPAL

MAN1A1

66

P33908
HVLLTATPVGLTLLI

INSRR

921

P14616
LATSALSLLTHPVLV

INHA

181

P05111
IHPTGLSTGALVAIL

CDH6

606

P55285
SLALHPDKTLVATGQ

EML6

66

Q6ZMW3
IFLKTGLPSTLLAHI

EPS15

251

P42566
LTLDKAHTLGSPLTL

FAM186A

1691

A6NE01
LPVATIFTTHATLLG

GYS1

196

P13807
LHAIATLSSVAPLLI

CFAP69

421

A5D8W1
LTLRPGVSLTGTKHN

DNAJA3

61

Q96EY1
DSLPVHVVLSLIGLA

SLC15A1

116

P46059
HAILIGSSLPLVESI

SACS

1191

Q9NZJ4
GIQFLHLPKLLTTST

GSTCD

336

Q8NEC7
AGSVVLIIHSPKSES

NIPA1

131

Q7RTP0
VSPREGSSLHKLLTL

PPRC1

156

Q5VV67
KTGIHTSTRLALIAP

PRPF3

361

O43395
ALGALPALTFLTVTH

PIDD1

166

Q9HB75
VSLSLLLIHPSEGAS

NXPE1

176

Q8N323
LGTPRLKTEHSITLQ

PCDHB9

426

Q9Y5E1
TPTLEILKSHISGIF

FES

421

P07332
VKQSGSLPLSSLTHV

ORC2

466

Q13416
SLSLGVPLHRLVSSV

RUSF1

326

Q96GQ5
GLASSLPAEVHSLTL

PLAGL1

251

Q9UM63
TALGLNALTKHVSPL

SFXN1

161

Q9H9B4
QVSLSLLLIHPSEGV

NXPE2

186

Q96DL1
SLSLLLIHPSEGVSA

NXPE4

176

Q6UWF7
IRLISGIQLPLTHSS

PLCZ1

486

Q86YW0
VLSPKTTISVAHLLA

FAM98A

256

Q8NCA5
PLTISRVHAGSKAAL

PDLIM4

26

P50479
LLISSILGSRTAGPH

MED24

906

O75448
TALTHRPDILILGTL

SIGLEC8

151

Q9NYZ4
TLTKGCHDSPLLLST

SIK3

1116

Q9Y2K2
LLSLESLDLLPSVHG

SHISA6

11

Q6ZSJ9
FASKHIIGLVPASIS

MYCBP2

1081

O75592
AAGILSAHKIIASSP

PYCR2

21

Q96C36
SPLKVLESHSRGILS

SEC31B

251

Q9NQW1
SLPATHIRGKCSVTL

MTA1

116

Q13330
TLSIVKAHGPTVSLL

MROH2B

206

Q7Z745
GKTATLHCTVTSLLP

SIRPG

46

Q9P1W8
SIHIELGSTLRLSPL

ARHGAP44

781

Q17R89
FGSKTIHLTGRSLLP

SGSH

336

P51688
FTHLEVSPITGRSKL

OMA1

211

Q96E52
HLPLKLVLSATLTGT

STRA6

291

Q9BX79
GLTVSSPLKRSHSLA

SSH1

966

Q8WYL5
LPGLKFEVISSAHIS

B4GALNT4

266

Q76KP1
LSLKSGISLGSPFHL

APC

2136

P25054
VGHLISTKPSLSLTT

CLEC20A

136

Q6ZU45
HSLLSVPKILRISSG

TP53TG5

71

Q9Y2B4
VRSLSLSLADSGHLP

PKP3

281

Q9Y446
HVVDARAGPSLKTTL

SINHCAF

76

Q9NP50
DSSKTLLCLSLTGPH

PDCD11

1211

Q14690
LQHIPKTISLSGSLD

SUN5

276

Q8TC36
HLASLGLSISKPDVV

ZNF565

81

Q8N9K5
ISPIKLHLSVSLSSG

VPS13A

2771

Q96RL7
HLGSLSLSPALSVAL

TEP1

1921

Q99973
GSVTALHVLPELLVT

TEP1

2556

Q99973
PEISHLSVGSILLVT

M6PR

181

P20645
SIAGPVLLILVHASL

PRAF2

126

O60831
SLLDLHLPRFSISGT

SERPINA11

306

Q86U17
ILLSQTTGVAIPLHA

TPR

616

P12270
HLLSKDGASLSPATL

PLCD3

766

Q8N3E9
PTTVSHKAALAGLSL

IGHMBP2

406

P38935
ILGSLGLLVSSSPAH

PLEKHG4B

1206

Q96PX9
GTLCLILLPGTKSTH

REXO5

736

Q96IC2
GLEVTHSSLLLAVLL

SPOCD1

1001

Q6ZMY3
HLLNSGTKDVPITSV

TMEM131

346

Q92545
HIRGLVASKPTLATL

NISCH

231

Q9Y2I1
AGHSVSKPDLITLLE

ZNF607

46

Q96SK3
AISKHLVGLTVIPDS

TEX10

756

Q9NXF1
FITPTGHSLKSLDLV

SEPTIN8

156

Q92599
LLPAHSGLSLIISDA

STAB1

2406

Q9NY15
LLHKDRVVATSLPSG

SIGLEC1

636

Q9BZZ2
ATHCTISLALPLLTI

UBIAD1

276

Q9Y5Z9
HLISLGSSISKPDVI

ZNF780A

41

O75290
HLISLGSSISKPDVI

ZNF780B

41

Q9Y6R6
VTFLSIHPSGKLALS

PAK1IP1

126

Q9NWT1
LLKVHVDPSGTFLAT

WDR62

676

O43379
HAARPPIKLLLSSSV

ZCCHC14

631

Q8WYQ9
TAIVHIQLIPGSSSK

SLC30A4

371

O14863
LHPSETRTLVAVGAK

WDR76

321

Q9H967
KIPLLTTIRHNTFTG

WDR76

531

Q9H967
HLVSLGLSISKPDVV

ZNF140

41

P52738
PLVLLLTLLGSSHGT

SFTA2

6

Q6UW10
LCLLLHLPSGTSVTL

SFTA2

51

Q6UW10
LARHTPTGTLVTIKI

STRADB

76

Q9C0K7
TLLALAGIAHPSALS

PIEZO1

206

Q92508
QLLIFATAHSPTGII

ERVK-19

341

Q9WJR5
PSHLTLLTSEGIVFI

WDR11

171

Q9BZH6
SSSVLLEHLRSPLGA

ZNF629

751

Q9UEG4
ATAHPLLELSKGNTV

TRIM50

301

Q86XT4
LLSLFSTPHGAKSII

UPRT

266

Q96BW1
LTHLILLPKSVGAIT

WDR87

521

Q6ZQQ6
SLSTVLLGLHSPIAL

ZFYVE26

1396

Q68DK2
GSKILLTLPEQHRAS

ZFYVE26

1656

Q68DK2
THSIIPRGSLSLKVL

TRRAP

211

Q9Y4A5
AAETTLKTAPLGRHI

XIRP1

1221

Q702N8
VFRIPVHSSALTLKS

WWC3

671

Q9ULE0
TGSHLKPFLLRTLSE

TTLL5

101

Q6EMB2
LLLVTGHLSKPFLRT

TARM1

116

B6A8C7
SHLVSLGILHSKPEL

ZNF337

46

Q9Y3M9
SISSLHLIGAPEKIQ

VPS13D

81

Q5THJ4
HILTLVAFSGTEKLP

MUSK

11

O15146
ISTLAAGHKTLVPEL

MMUT

671

P22033