Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

2.98e-062352GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

2.98e-062352GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

8.94e-063352GO:0043993
GeneOntologyMolecularFunctionSMAD binding

COL3A1 PRDM16 CREBBP EP300

1.52e-0586354GO:0046332
GeneOntologyMolecularFunctionhistone H3K9 monomethyltransferase activity

PRDM16 SETD5

8.30e-058352GO:0140948
GeneOntologyMolecularFunctionzinc ion binding

ZNF8 NFXL1 TRIM54 ZFYVE1 TRIM61 CREBBP LIN28A EP300

1.22e-04891358GO:0008270
GeneOntologyMolecularFunctionhistone H3K9me2 methyltransferase activity

PRDM16 SETD5

1.33e-0410352GO:0140947
GeneOntologyMolecularFunctionhistone H3K9 methyltransferase activity

PRDM16 SETD5

2.30e-0413352GO:0046974
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

3.09e-0415352GO:0010484
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP12 LRP1B

3.53e-0416352GO:0005041
GeneOntologyMolecularFunctionmethyltransferase activity

TRMT1L PRDM5 PRDM16 SETD5

5.09e-04213354GO:0008168
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

6.14e-0421352GO:0042975
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP12 LRP1B

6.14e-0421352GO:0030228
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

TRMT1L PRDM5 PRDM16 SETD5

6.14e-04224354GO:0016741
GeneOntologyMolecularFunctionhistone modifying activity

PRDM16 SETD5 CREBBP EP300

6.67e-04229354GO:0140993
GeneOntologyMolecularFunctionN-methyltransferase activity

TRMT1L PRDM16 SETD5

8.18e-04105353GO:0008170
GeneOntologyMolecularFunctiontransition metal ion binding

ZNF8 NFXL1 TRIM54 ZFYVE1 TRIM61 CREBBP LIN28A EP300

8.58e-041189358GO:0046914
GeneOntologyMolecularFunctionactin binding

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

1.39e-03479355GO:0003779
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300

1.91e-0337352GO:0043425
GeneOntologyMolecularFunctioncytoskeletal protein binding

TRIM54 SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 EP300 SPATA31A7

2.60e-031099357GO:0008092
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

PRDM16 SETD5

2.70e-0344352GO:0140938
GeneOntologyMolecularFunctionchromatin DNA binding

REPIN1 CREBBP EP300

3.09e-03167353GO:0031490
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

TRMT1L PRDM16 SETD5

3.36e-03172353GO:0008757
GeneOntologyMolecularFunctionintegrin binding

COL3A1 THBS1 FBN1

3.52e-03175353GO:0005178
GeneOntologyMolecularFunctionhistone acetyltransferase activity

CREBBP EP300

3.61e-0351352GO:0004402
GeneOntologyMolecularFunctiontranscription coactivator binding

CREBBP EP300

4.03e-0354352GO:0001223
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

CREBBP EP300

4.18e-0355352GO:0061733
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL3A1 THBS1 FBN1

4.31e-03188353GO:0005201
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

CREBBP EP300

4.96e-0360352GO:0034212
GeneOntologyMolecularFunctionmodification-dependent protein binding

CHD1 SETD5 EP300

5.55e-03206353GO:0140030
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

PRDM16 SETD5

6.32e-0368352GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

PRDM16 SETD5

6.51e-0369352GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

PRDM16 SETD5

6.88e-0371352GO:0042054
GeneOntologyMolecularFunctionp53 binding

CREBBP EP300

8.04e-0377352GO:0002039
GeneOntologyMolecularFunctionN-acetyltransferase activity

CREBBP EP300

8.25e-0378352GO:0008080
GeneOntologyMolecularFunctioncalcium ion binding

THBS1 FAT2 FBN1 LRP1B NOTCH4

9.36e-03749355GO:0005509
GeneOntologyMolecularFunctiondamaged DNA binding

CREBBP EP300

9.51e-0384352GO:0003684
GeneOntologyMolecularFunctioncargo receptor activity

LRP12 LRP1B

9.73e-0385352GO:0038024
GeneOntologyMolecularFunctionmethylated histone binding

CHD1 SETD5

9.95e-0386352GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

CHD1 SETD5

1.04e-0288352GO:0140034
GeneOntologyMolecularFunctionacyltransferase activity

TRIM54 RNF123 TRIM61 CREBBP EP300

1.07e-02775355GO:0016746
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF449 ZNF8 NFXL1 PRDM5 PRDM16 CREBBP EP300

1.21e-021459357GO:0000977
GeneOntologyMolecularFunctionN-acyltransferase activity

CREBBP EP300

1.38e-02102352GO:0016410
GeneOntologyMolecularFunctionprotein methyltransferase activity

PRDM16 SETD5

1.40e-02103352GO:0008276
GeneOntologyMolecularFunctionacetyltransferase activity

CREBBP EP300

1.43e-02104352GO:0016407
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

COL3A1 THBS1 FBN1 PRDM16 CREBBP EP300

6.37e-06276356GO:0007179
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

COL3A1 ZNF8 THBS1 FBN1 PRDM16 CREBBP EP300

8.28e-06445357GO:0141091
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

COL3A1 ZNF8 THBS1 FBN1 PRDM16 CREBBP EP300

1.39e-05482357GO:0007178
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

1.67e-054352GO:0018076
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

THBS1 FBN1 PRDM16 CREBBP EP300

1.72e-05192355GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

THBS1 FBN1 PRDM16 CREBBP EP300

1.85e-05195355GO:1903844
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

COL3A1 THBS1 FBN1 PRDM16 CREBBP EP300

1.95e-05336356GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

COL3A1 THBS1 FBN1 PRDM16 CREBBP EP300

2.19e-05343356GO:0071559
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

THBS1 CREBBP EP300

2.82e-0535353GO:1903846
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

THBS1 CREBBP EP300

2.82e-0535353GO:0030511
GeneOntologyBiologicalProcesspositive regulation of sarcomere organization

PRKD1 EP300

5.84e-057352GO:0060298
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

COL3A1 ZNF8 THBS1 PRKD1 FBN1 PRDM16 CREBBP EP300

7.03e-05850358GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

COL3A1 ZNF8 THBS1 PRKD1 FBN1 PRDM16 CREBBP EP300

9.18e-05883358GO:0070848
GeneOntologyBiologicalProcesstransforming growth factor beta1 production

COL3A1 THBS1

2.16e-0413352GO:0032905
GeneOntologyBiologicalProcessregulation of sarcomere organization

PRKD1 EP300

2.16e-0413352GO:0060297
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

THBS1 FBN1 PRDM16 CREBBP EP300

2.81e-04347355GO:0090092
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

CREBBP EP300

3.31e-0416352GO:0006474
GeneOntologyBiologicalProcessregulation of cellular response to heat

CREBBP EP300

3.31e-0416352GO:1900034
GeneOntologyBiologicalProcesscellular response to heat

THBS1 CREBBP EP300

3.49e-0481353GO:0034605
GeneOntologyBiologicalProcesspositive regulation by host of viral transcription

CHD1 EP300

3.74e-0417352GO:0043923
GeneOntologyBiologicalProcesspositive regulation of cell size

PRKD1 EP300

4.70e-0419352GO:0045793
GeneOntologyBiologicalProcessmodulation by host of symbiont process

CHD1 ZFYVE1 EP300

4.91e-0491353GO:0051851
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

THBS1 FBN1 PRDM16 CREBBP EP300

6.15e-04412355GO:0090287
GeneOntologyBiologicalProcessmethylation

TRMT1L PRDM5 PRDM16 SETD5

6.41e-04234354GO:0032259
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

COL3A1 ZNF8 THBS1 PRKD1 FBN1 PRDM16 CREBBP EP300

6.82e-041186358GO:0007167
GeneOntologyBiologicalProcessregulation of cell adhesion molecule production

CREBBP NOTCH4

6.92e-0423352GO:0060353
GeneOntologyBiologicalProcessstimulatory C-type lectin receptor signaling pathway

CREBBP EP300

6.92e-0423352GO:0002223
GeneOntologyBiologicalProcesscellular response to lectin

CREBBP EP300

6.92e-0423352GO:1990858
GeneOntologyBiologicalProcessresponse to lectin

CREBBP EP300

6.92e-0423352GO:1990840
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

ZNF449 SMCP SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 LIN28A SPATA31A7

7.13e-041194358GO:0048609
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

PRKD1 EP300 NOTCH4

7.66e-04106353GO:0051149
GeneOntologyBiologicalProcesscell adhesion molecule production

CREBBP NOTCH4

8.86e-0426352GO:0060352
GeneOntologyBiologicalProcessregulation of endothelial cell chemotaxis

THBS1 PRKD1

8.86e-0426352GO:2001026
GeneOntologyBiologicalProcesspositive regulation of protein localization to nucleus

PRKD1 CREBBP EP300

9.46e-04114353GO:1900182
GeneOntologyBiologicalProcesspeptide cross-linking

COL3A1 THBS1

9.56e-0427352GO:0018149
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

THBS1 CREBBP EP300

9.70e-04115353GO:0090100
GeneOntologyBiologicalProcesscellular response to nutrient levels

PRKD1 ZFYVE1 CREBBP EP300

9.77e-04262354GO:0031669
GeneOntologyBiologicalProcesspeptidyl-lysine acetylation

CREBBP EP300

1.03e-0328352GO:0018394
GeneOntologyBiologicalProcessregulation of brown fat cell differentiation

FBN1 PRDM16

1.10e-0329352GO:0090335
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

CREBBP EP300

1.10e-0329352GO:0031365
GeneOntologyBiologicalProcessresponse to heat

THBS1 CREBBP EP300

1.12e-03121353GO:0009408
GeneOntologyBiologicalProcessgamete generation

ZNF449 SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 LIN28A SPATA31A7

1.13e-03982357GO:0007276
GeneOntologyBiologicalProcessrespiratory tube development

COL3A1 FBN1 HECA EP300

1.14e-03273354GO:0030323
GeneOntologyBiologicalProcesssexual reproduction

ZNF449 SMCP SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 LIN28A SPATA31A7

1.32e-031312358GO:0019953
GeneOntologyBiologicalProcessspermatogenesis

ZNF449 SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

1.43e-03744356GO:0007283
GeneOntologyBiologicalProcessbiological process involved in interaction with symbiont

CHD1 ZFYVE1 EP300

1.54e-03135353GO:0051702
GeneOntologyBiologicalProcessendothelial cell chemotaxis

THBS1 PRKD1

1.61e-0335352GO:0035767
GeneOntologyBiologicalProcessmale gamete generation

ZNF449 SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

1.62e-03762356GO:0048232
GeneOntologyCellularComponentacrosomal vesicle

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

2.26e-05206355GO:0001669
HumanPhenoAbnormal atrioventricular valve morphology

COL3A1 PRKD1 FBN1 PRDM5 PRDM16 CREBBP EP300

1.77e-06350117HP:0006705
HumanPhenoMitral valve prolapse

COL3A1 FBN1 PRDM5 CREBBP EP300

3.11e-06123115HP:0001634
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

4.24e-062112HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

4.24e-062112HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

4.24e-062112HP:0001042
HumanPhenoPulmonic stenosis

COL3A1 FBN1 PRDM5 CREBBP EP300

5.50e-06138115HP:0001642
HumanPhenoAbnormal mitral valve morphology

COL3A1 FBN1 PRDM5 PRDM16 CREBBP EP300

5.81e-06257116HP:0001633
HumanPhenoDental crowding

COL3A1 FBN1 SETD5 CREBBP EP300

6.79e-06144115HP:0000678
HumanPhenoAbnormal mitral valve morphology

COL3A1 FBN1 PRDM5 CREBBP EP300

7.26e-06146115HP:0031477
HumanPhenoBroad phalanx

PRKD1 FBN1 SETD5 CREBBP EP300

7.77e-06148115HP:0006009
HumanPhenoBroad phalanges of the hand

PRKD1 FBN1 SETD5 CREBBP EP300

7.77e-06148115HP:0009768
HumanPhenoAbsent earlobe

COL3A1 CREBBP EP300

8.37e-0620113HP:0000387
HumanPhenoBroad finger

PRKD1 FBN1 SETD5 CREBBP EP300

9.44e-06154115HP:0001500
HumanPhenoDeep plantar creases

PRKD1 CREBBP EP300

9.76e-0621113HP:0001869
HumanPhenoCorneal scarring

PRDM5 CREBBP EP300

9.76e-0621113HP:0000559
HumanPhenoHigh, narrow palate

COL3A1 LRP12 FBN1 CREBBP EP300

1.01e-05156115HP:0002705
HumanPhenoAbnormal eyebrow morphology

COL3A1 CHD1 PRKD1 FBN1 PRDM16 SETD5 CREBBP EP300

1.03e-05674118HP:0000534
HumanPhenoBroad long bones

PRKD1 FBN1 SETD5 CREBBP EP300

1.04e-05157115HP:0005622
HumanPhenoAbnormal pulmonary valve physiology

COL3A1 FBN1 PRDM5 CREBBP EP300

1.25e-05163115HP:0031654
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

1.27e-053112HP:0008752
HumanPhenoPhobia

CREBBP EP300

1.27e-053112HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

1.27e-053112HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

1.27e-053112HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

1.27e-053112HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

1.27e-053112HP:0005895
HumanPhenoDeep philtrum

FBN1 SETD5 CREBBP EP300

1.32e-0575114HP:0002002
HumanPhenoMinor feet anomalies

PRKD1 CREBBP EP300

1.90e-0526113HP:0010613
HumanPhenoAbnormal feet morphology

PRKD1 CREBBP EP300

1.90e-0526113HP:0010611
HumanPhenoBroad distal phalanx of finger

SETD5 CREBBP EP300

2.13e-0527113HP:0009836
HumanPhenoSmooth philtrum

COL3A1 FBN1 SETD5 CREBBP EP300

2.32e-05185115HP:0000319
HumanPhenoTrichiasis

CREBBP EP300

2.54e-054112HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

2.54e-054112HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

2.54e-054112HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

2.54e-054112HP:0006200
HumanPhenoVascular ring

CREBBP EP300

2.54e-054112HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

2.54e-054112HP:0031207
HumanPhenoBroad eyebrow

CHD1 CREBBP EP300

2.66e-0529113HP:0011229
HumanPhenoFlared metaphysis

PRKD1 FBN1 SETD5 CREBBP EP300

2.70e-05191115HP:0003015
HumanPhenoAbnormal pulmonary valve morphology

COL3A1 FBN1 PRDM5 CREBBP EP300

3.22e-05198115HP:0001641
HumanPhenoNarrow palate

COL3A1 LRP12 FBN1 CREBBP EP300

3.55e-05202115HP:0000189
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

4.22e-055112HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

4.22e-055112HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

4.22e-055112HP:0030421
HumanPhenoAspiration

LRP12 CREBBP EP300

4.32e-0534113HP:0002835
HumanPhenoScarring

COL3A1 PRDM5 CREBBP EP300

4.49e-05102114HP:0100699
HumanPhenoAbnormal heart valve morphology

COL3A1 PRKD1 FBN1 PRDM5 PRDM16 CREBBP EP300

5.73e-05588117HP:0001654
HumanPhenoLarge foramen magnum

CREBBP EP300

6.33e-056112HP:0002700
HumanPhenoMetaphyseal widening

PRKD1 FBN1 SETD5 CREBBP EP300

6.92e-05232115HP:0003016
HumanPhenoNarrow mouth

COL3A1 FBN1 PRDM16 CREBBP EP300

7.22e-05234115HP:0000160
HumanPhenoAbnormal heart valve physiology

COL3A1 FBN1 PRDM5 PRDM16 CREBBP EP300

7.75e-05403116HP:0031653
HumanPhenoAbnormal toe morphology

COL3A1 PRKD1 FBN1 PRDM5 PRDM16 SETD5 CREBBP EP300

8.67e-05893118HP:0001780
HumanPhenoDeviated nasal septum

CREBBP EP300

8.85e-057112HP:0004411
HumanPhenoHip dysplasia

COL3A1 PRDM5 PRDM16 CREBBP EP300

9.35e-05247115HP:0001385
HumanPhenoTooth malposition

COL3A1 PRKD1 FBN1 SETD5 CREBBP EP300

9.53e-05418116HP:0000692
HumanPhenoProminent fingertip pads

CHD1 CREBBP EP300

1.08e-0446113HP:0001212
HumanPhenoLong eyelashes

CHD1 FBN1 CREBBP EP300

1.13e-04129114HP:0000527
HumanPhenoAbnormal morphology of bones of the upper limbs

COL3A1 PRKD1 FBN1 SETD5 CREBBP EP300

1.21e-04436116HP:0040065
HumanPhenoProminent digit pad

CHD1 CREBBP EP300

1.23e-0448113HP:0011298
HumanPhenoAbnormal nasal dorsum morphology

COL3A1 FBN1 PRDM16 CREBBP EP300

1.24e-04262115HP:0011119
HumanPhenoDeeply set eye

COL3A1 FBN1 PRDM16 CREBBP EP300

1.33e-04266115HP:0000490
HumanPhenoAbnormal lacrimal duct morphology

COL3A1 CREBBP EP300

1.39e-0450113HP:0011481
HumanPhenoCutaneous syndactyly of toes

PRKD1 CREBBP EP300

1.39e-0450113HP:0010621
HumanPhenoPilomatrixoma

CREBBP EP300

1.51e-049112HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

1.51e-049112HP:0002341
HumanPhenoAplasia/Hypoplasia of the earlobes

COL3A1 CREBBP EP300

1.65e-0453113HP:0009906
HumanPhenoNarrow nasal bridge

COL3A1 CREBBP EP300

1.65e-0453113HP:0000446
HumanPhenoAbnormal eyelash morphology

COL3A1 CHD1 FBN1 CREBBP EP300

1.82e-04284115HP:0000499
HumanPhenoDuplication involving bones of the feet

PRDM16 SETD5 CREBBP EP300

1.88e-04147114HP:0009136
HumanPhenoFoot polydactyly

PRDM16 SETD5 CREBBP EP300

1.88e-04147114HP:0001829
HumanPhenoFrontal hirsutism

CREBBP EP300

1.89e-0410112HP:0011335
HumanPhenoHypermetropia

COL3A1 PRDM16 SETD5 CREBBP EP300

1.94e-04288115HP:0000540
HumanPhenoAbnormality of refraction

COL3A1 FBN1 PRDM5 PRDM16 SETD5 CREBBP EP300

1.95e-04709117HP:0000539
HumanPhenoAbnormal upper limb bone morphology

COL3A1 PRKD1 FBN1 SETD5 CREBBP EP300

2.18e-04484116HP:0040070
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

2.31e-0411112HP:0031251
HumanPhenoAbnormal dental morphology

COL3A1 PRKD1 FBN1 CREBBP EP300

2.32e-04299115HP:0006482
HumanPhenoAbnormal hip joint morphology

COL3A1 FBN1 PRDM5 PRDM16 CREBBP EP300

2.33e-04490116HP:0001384
HumanPhenoAbnormal finger morphology

COL3A1 CHD1 PRKD1 FBN1 PRDM5 PRDM16 SETD5 CREBBP EP300

2.51e-041385119HP:0001167
HumanPhenoFrontal bossing

CHD1 PRKD1 FBN1 PRDM16 SETD5 CREBBP EP300

2.53e-04738117HP:0002007
HumanPhenoAbnormal finger phalanx morphology

COL3A1 PRKD1 FBN1 PRDM16 SETD5 CREBBP EP300

2.53e-04738117HP:0005918
HumanPhenoShort phalanx of finger

PRKD1 FBN1 SETD5 CREBBP EP300

2.59e-04306115HP:0009803
HumanPhenoAbnormal shape of the frontal region

CHD1 PRKD1 FBN1 PRDM16 SETD5 CREBBP EP300

2.59e-04741117HP:0011218
HumanPhenoAbnormal frontal bone morphology

CHD1 PRKD1 FBN1 PRDM16 SETD5 CREBBP EP300

2.61e-04742117HP:0430000
HumanPhenoAbnormal synovial membrane morphology

COL3A1 FBN1 PRDM5 PRDM16 CREBBP EP300

2.70e-04503116HP:0005262
HumanPhenoAplasia/Hypoplasia of the phalanges of the hand

PRKD1 FBN1 SETD5 CREBBP EP300

3.15e-04319115HP:0009767
HumanPhenoAbnormal hair morphology

COL3A1 CHD1 PRKD1 FBN1 PRDM5 PRDM16 SETD5 CREBBP EP300

3.17e-041424119HP:0001595
HumanPhenoFacial grimacing

CREBBP EP300

3.26e-0413112HP:0000273
HumanPhenoKeloids

CREBBP EP300

3.26e-0413112HP:0010562
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

3.80e-0414112HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

3.80e-0414112HP:0012304
HumanPhenoParietal foramina

CREBBP EP300

3.80e-0414112HP:0002697
HumanPhenoPulmonary artery dilatation

COL3A1 FBN1

3.80e-0414112HP:0004927
HumanPhenoDuplication of phalanx of toe

CREBBP EP300

4.38e-0415112HP:0010181
HumanPhenoSocial and occupational deterioration

CREBBP EP300

4.38e-0415112HP:0007086
HumanPhenoAtypical scarring of skin

COL3A1 CREBBP EP300

4.47e-0474113HP:0000987
HumanPhenoAbnormal metaphysis morphology

PRKD1 FBN1 SETD5 CREBBP EP300

4.49e-04344115HP:0000944
HumanPhenoScoliosis

COL3A1 PRKD1 FBN1 PRDM5 PRDM16 SETD5 CREBBP EP300

4.69e-041122118HP:0002650
HumanPhenoSquare face

CREBBP EP300

5.00e-0416112HP:0000321
HumanPhenoLipoatrophy

COL3A1 FBN1 PRDM16

5.42e-0479113HP:0100578
HumanPhenoPremature thelarche

CREBBP EP300

5.67e-0417112HP:0010314
HumanPhenoAbnormal aortic morphology

COL3A1 FBN1 PRDM16 CREBBP EP300

5.77e-04363115HP:0030963
MousePhenoabnormal heart ventricle morphology

TRIM54 THBS1 FBN1 PRDM16 SETD5 CREBBP LIN28A EP300

6.48e-05793268MP:0005294
MousePhenoaortic dissection

COL3A1 FBN1

1.19e-049262MP:0004044
MousePhenoabnormal maxilla morphology

CHD1 PRDM16 SETD5 CREBBP

1.35e-04144264MP:0000455
MousePhenohemorrhage

TRIM54 THBS1 FBN1 MUC13 SETD5 CREBBP EP300

1.57e-04664267MP:0001914
DomainDUF4599

SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

3.96e-0912334PF15371
DomainDUF4599

SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

3.96e-0912334IPR027970
DomainEGF_3

THBS1 FAT2 FBN1 MUC13 LRP1B VWDE NOTCH4

1.48e-07235337PS50026
DomainEGF

THBS1 FAT2 FBN1 MUC13 LRP1B VWDE NOTCH4

1.48e-07235337SM00181
DomainEGF-like_dom

THBS1 FAT2 FBN1 MUC13 LRP1B VWDE NOTCH4

2.19e-07249337IPR000742
DomainEGF_1

THBS1 FAT2 FBN1 MUC13 LRP1B VWDE NOTCH4

2.57e-07255337PS00022
DomainEGF-like_CS

THBS1 FAT2 FBN1 MUC13 LRP1B VWDE NOTCH4

3.01e-07261337IPR013032
DomainEGF_2

THBS1 FAT2 FBN1 MUC13 LRP1B VWDE NOTCH4

3.33e-07265337PS01186
DomainEGF_CA

THBS1 FAT2 FBN1 LRP1B NOTCH4

2.25e-06122335SM00179
DomainEGF-like_Ca-bd_dom

THBS1 FAT2 FBN1 LRP1B NOTCH4

2.43e-06124335IPR001881
Domain-

CREBBP EP300

3.03e-0623321.10.246.20
Domainzf-TAZ

CREBBP EP300

3.03e-062332PF02135
DomainZF_TAZ

CREBBP EP300

3.03e-062332PS50134
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

3.03e-062332IPR014744
DomainHAT_KAT11

CREBBP EP300

3.03e-062332PF08214
DomainKIX

CREBBP EP300

3.03e-062332PS50952
DomainZnF_TAZ

CREBBP EP300

3.03e-062332SM00551
DomainCBP_P300_HAT

CREBBP EP300

3.03e-062332IPR031162
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

3.03e-062332IPR013178
DomainDUF902

CREBBP EP300

3.03e-062332PF06001
Domain-

CREBBP EP300

3.03e-0623321.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

3.03e-062332IPR010303
DomainKAT11

CREBBP EP300

3.03e-062332SM01250
Domain-

CREBBP EP300

3.03e-0623321.10.1630.10
DomainZnf_TAZ

CREBBP EP300

3.03e-062332IPR000197
DomainKIX_dom

CREBBP EP300

3.03e-062332IPR003101
DomainCreb_binding

CREBBP EP300

3.03e-062332PF09030
DomainKIX

CREBBP EP300

3.03e-062332PF02172
DomainCBP_P300_HAT

CREBBP EP300

3.03e-062332PS51727
DomainEGF_CA

THBS1 FBN1 LRP1B NOTCH4

1.55e-0586334PF07645
DomainNuc_rcpt_coact

CREBBP EP300

4.52e-056332IPR009110
DomainSET

PRDM5 PRDM16 SETD5

7.24e-0546333SM00317
DomainSET_dom

PRDM5 PRDM16 SETD5

9.31e-0550333IPR001214
DomainSET

PRDM5 PRDM16 SETD5

9.31e-0550333PS50280
DomainGrowth_fac_rcpt_

FBN1 MUC13 LRP1B NOTCH4

1.59e-04156334IPR009030
DomainZF_ZZ_2

CREBBP EP300

4.55e-0418332PS50135
DomainZF_ZZ_1

CREBBP EP300

4.55e-0418332PS01357
DomainZZ

CREBBP EP300

4.55e-0418332PF00569
DomainZnf_ZZ

CREBBP EP300

5.08e-0419332IPR000433
DomainZnF_ZZ

CREBBP EP300

5.08e-0419332SM00291
DomainEGF_Ca-bd_CS

FBN1 LRP1B NOTCH4

6.62e-0497333IPR018097
DomainEGF_CA

FBN1 LRP1B NOTCH4

7.02e-0499333PS01187
DomainASX_HYDROXYL

FBN1 LRP1B NOTCH4

7.23e-04100333PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 LRP1B NOTCH4

8.57e-04106333IPR000152
DomaincEGF

FBN1 LRP1B

9.58e-0426332IPR026823
DomaincEGF

FBN1 LRP1B

9.58e-0426332PF12662
DomainBromodomain_CS

CREBBP EP300

9.58e-0426332IPR018359
DomainVWC

COL3A1 THBS1

1.11e-0328332PF00093
DomainEGF

FAT2 LRP1B NOTCH4

1.41e-03126333PF00008
DomainZF_RING_1

NFXL1 TRIM54 RNF123 TRIM61

1.65e-03291334PS00518
DomainZF_RING_2

NFXL1 TRIM54 RNF123 TRIM61

1.80e-03298334PS50089
DomainVWFC_1

COL3A1 THBS1

1.84e-0336332PS01208
DomainBROMODOMAIN_1

CREBBP EP300

1.94e-0337332PS00633
DomainVWC

COL3A1 THBS1

2.05e-0338332SM00214
DomainBromodomain

CREBBP EP300

2.05e-0338332PF00439
DomainVWFC_2

COL3A1 THBS1

2.05e-0338332PS50184
DomainZINC_FINGER_C2H2_2

ZNF449 ZNF8 TRMT1L PRDM5 PRDM16 REPIN1

2.12e-03775336PS50157
DomainZINC_FINGER_C2H2_1

ZNF449 ZNF8 TRMT1L PRDM5 PRDM16 REPIN1

2.15e-03777336PS00028
Domainzf-C2H2_6

ZNF449 ZNF8 PRDM5 PRDM16

2.18e-03314334PF13912
DomainLDLR_class-A_CS

LRP12 LRP1B

2.26e-0340332IPR023415
DomainBROMODOMAIN_2

CREBBP EP300

2.38e-0341332PS50014
DomainSET

PRDM5 SETD5

2.38e-0341332PF00856
DomainZnf_C2H2-like

ZNF449 ZNF8 TRMT1L PRDM5 PRDM16 REPIN1

2.43e-03796336IPR015880
DomainBROMO

CREBBP EP300

2.49e-0342332SM00297
DomainBromodomain

CREBBP EP300

2.49e-0342332IPR001487
Domain-

CREBBP EP300

2.49e-03423321.20.920.10
DomainVWF_dom

COL3A1 THBS1

2.49e-0342332IPR001007
DomainZnf_RING

NFXL1 TRIM54 RNF123 TRIM61

2.50e-03326334IPR001841
DomainZnf_C2H2

ZNF449 ZNF8 TRMT1L PRDM5 PRDM16 REPIN1

2.57e-03805336IPR007087
DomainZnF_C2H2

ZNF449 ZNF8 TRMT1L PRDM5 PRDM16 REPIN1

2.62e-03808336SM00355
DomainLdl_recept_a

LRP12 LRP1B

2.86e-0345332PF00057
Domain-

LRP12 LRP1B

2.98e-03463324.10.400.10
DomainLDLRA_1

LRP12 LRP1B

3.25e-0348332PS01209
DomainLDrepeatLR_classA_rpt

LRP12 LRP1B

3.38e-0349332IPR002172
DomainLDLa

LRP12 LRP1B

3.38e-0349332SM00192
DomainLDLRA_2

LRP12 LRP1B

3.38e-0349332PS50068
DomainLaminin_G

THBS1 FAT2

4.70e-0358332IPR001791
Domain-

ZNF449 ZNF8 PRDM5 PRDM16 REPIN1

6.38e-036793353.30.160.60
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

THBS1 FBN1 CREBBP EP300

8.10e-0759184M39886
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300 NOTCH4

1.97e-0620183M27881
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.54e-055182MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

1.54e-055182M48020
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

1.54e-055182M27228
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

1.54e-055182M48023
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.30e-056182M22062
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

CREBBP EP300 NOTCH4

2.74e-0547183M7946
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

3.22e-057182MM1573
PathwayWP_TGFBETA_SIGNALING_PATHWAY

THBS1 CREBBP EP300

3.93e-0553183MM15880
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

4.29e-058182M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

4.29e-058182M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

4.29e-058182M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

4.29e-058182M46443
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

THBS1 CREBBP EP300

4.40e-0555183M39351
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

5.51e-059182M47451
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

6.89e-0510182M27945
PathwayPID_INTEGRIN1_PATHWAY

COL3A1 THBS1 FBN1

7.61e-0566183M18
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THBS1 MUC13 NOTCH4

8.32e-0568183M27303
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

8.41e-0511182MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

8.41e-0511182M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

8.41e-0511182M26924
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

COL3A1 CREBBP EP300

8.69e-0569183M48052
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.01e-0412182M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

1.01e-0412182M27765
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL3A1 THBS1 FBN1

1.16e-0476183MM14867
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

1.39e-0414182M27808
PathwayREACTOME_SIGNALING_BY_NOTCH4

CREBBP EP300 NOTCH4

1.45e-0482183M594
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.60e-0415182MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.60e-0415182M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.60e-0415182MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

1.60e-0415182M953
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL3A1 THBS1 FBN1

1.62e-0485183M16441
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

THBS1 CREBBP EP300

1.67e-0486183M2642
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.83e-0416182M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

1.83e-0416182MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.83e-0416182M8516
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

1.83e-0416182M27121
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

1.83e-0416182M27940
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.07e-0417182MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

2.07e-0417182M48025
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

2.33e-0418182M26942
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.60e-0419182M18933
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

2.60e-0419182M46442
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

PRKD1 CREBBP EP300

2.69e-04101183MM15829
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

PRKD1 CREBBP EP300

2.69e-04101183M39387
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

3.19e-0421182M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

3.19e-0421182M27485
PathwayREACTOME_ADIPOGENESIS

PRDM16 CREBBP EP300

3.46e-04110183M48259
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

3.50e-0422182MM1443
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

3.50e-0422182MM1370
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

3.83e-0423182M2821
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

4.18e-0424182M13404
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

CREBBP EP300 NOTCH4

4.36e-04119183M607
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

4.54e-0425182M27880
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP EP300

4.91e-0426182M2499
PathwayPID_HDAC_CLASSIII_PATHWAY

CREBBP EP300

4.91e-0426182M32
PathwayREACTOME_SYNDECAN_INTERACTIONS

COL3A1 THBS1

5.30e-0427182M27217
PathwayREACTOME_ATTENUATION_PHASE

CREBBP EP300

5.71e-0428182M27254
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

CREBBP NOTCH4

5.71e-0428182M6177
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP EP300

6.56e-0430182M207
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

COL3A1 THBS1

6.56e-0430182M39641
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

CREBBP EP300

6.56e-0430182M936
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

COL3A1 THBS1

6.56e-0430182MM15812
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC13 CREBBP EP300

7.01e-04140183M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

THBS1 MUC13 NOTCH4

7.46e-04143183M27275
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP EP300

7.47e-0432182M39521
PathwayWP_MALE_INFERTILITY

THBS1 CREBBP EP300

7.77e-04145183M39856
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

CHD1 CREBBP EP300

8.40e-04149183M27888
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

CREBBP EP300

8.43e-0434182M39771
PathwayPID_HIF2PATHWAY

CREBBP EP300

8.43e-0434182M44
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

CREBBP EP300

8.94e-0435182M48246
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

1.05e-0338182M27757
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CREBBP EP300

1.05e-0338182M27255
PathwayREACTOME_SIGNALING_BY_NOTCH

EP300 NOTCH4

1.11e-0339182MM14604
PathwayPID_FOXM1_PATHWAY

CREBBP EP300

1.17e-0340182M176
PathwayPID_IFNG_PATHWAY

CREBBP EP300

1.17e-0340182M161
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

CREBBP EP300

1.29e-0342182M17541
PathwayWP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS

COL3A1 THBS1

1.35e-0343182M39565
PathwayPID_INTEGRIN3_PATHWAY

THBS1 FBN1

1.35e-0343182M53
PathwayPID_HNF3A_PATHWAY

CREBBP EP300

1.41e-0344182M285
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

CREBBP EP300

1.41e-0344182M27295
PathwayWP_NOTCH_SIGNALING_WP268

CREBBP NOTCH4

1.48e-0345182M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

CREBBP NOTCH4

1.54e-0346182MM15971
PathwayPID_HES_HEY_PATHWAY

CREBBP EP300

1.68e-0348182M288
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

1.68e-0348182M611
PathwayPID_FOXO_PATHWAY

CREBBP EP300

1.75e-0349182M136
PathwayREACTOME_HEME_SIGNALING

CREBBP EP300

1.75e-0349182M41832
PathwayREACTOME_SIGNALING_BY_NOTCH3

CREBBP EP300

1.75e-0349182M618
PathwayBIOCARTA_PPARA_PATHWAY

CREBBP EP300

1.97e-0352182M2404
PathwayPID_NFAT_3PATHWAY

CREBBP EP300

2.04e-0353182M113
PathwayPID_AR_TF_PATHWAY

CREBBP EP300

2.04e-0353182M151
PathwayREACTOME_SIGNALING_BY_PDGF

COL3A1 THBS1

2.36e-0357182MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

COL3A1 THBS1

2.44e-0358182M2049
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

CREBBP EP300

2.44e-0358182M29616
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL3A1 THBS1

2.52e-0359182M27218
PathwayPID_NOTCH_PATHWAY

EP300 NOTCH4

2.52e-0359182M17
PathwayPID_P53_REGULATION_PATHWAY

CREBBP EP300

2.52e-0359182M261
PathwayREACTOME_ESR_MEDIATED_SIGNALING

CHD1 CREBBP EP300

2.57e-03220183M27794
PathwayWP_NOTCH_SIGNALING_WP61

EP300 NOTCH4

2.70e-0361182M39540
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

4.59e-15635520850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

4.59e-15635525930072
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5 SPATA31A7

3.21e-112435532212159
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

NFXL1 LRP12 THBS1 FBN1

7.96e-077135433541421
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

9.84e-07235227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

9.84e-07235234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

9.84e-07235219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

9.84e-07235215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

9.84e-07235229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

9.84e-07235224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

9.84e-07235233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

9.84e-0723529018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

9.84e-07235224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

9.84e-07235230135524
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

9.84e-07235239287984
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

9.84e-07235216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

9.84e-07235229217654
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

9.84e-07235220717166
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

9.84e-07235210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

9.84e-07235227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

9.84e-07235229170789
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

9.84e-07235225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

9.84e-07235211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

9.84e-07235221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

9.84e-07235212646247
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

9.84e-07235232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

9.84e-07235219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

9.84e-07235224522976
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

9.84e-07235211867645
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

9.84e-07235221847097
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

9.84e-07235211963968
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

9.84e-07235234813504
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

9.84e-0723529528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

9.84e-07235212696060
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

9.84e-07235220301699
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

9.84e-07235236109165
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

9.84e-07235224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

9.84e-07235237816914
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

9.84e-07235212242694
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

9.84e-07235211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

9.84e-07235210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

9.84e-07235231182547
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

9.84e-07235235502657
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

9.84e-07235230635043
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

9.84e-07235231898871
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

9.84e-07235227648933
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

9.84e-07235230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

9.84e-07235227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

9.84e-07235219272189
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

9.84e-07235210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

9.84e-07235237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

9.84e-07235212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

9.84e-07235215641773
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

9.84e-07235232690000
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

9.84e-0723529733868
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

9.84e-07235230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

9.84e-07235221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

9.84e-0723529811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

9.84e-07235224089570
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

9.84e-07235233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

9.84e-07235234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

9.84e-07235222177454
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

9.84e-07235215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

9.84e-07235239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

9.84e-07235222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

9.84e-07235234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

9.84e-07235234019788
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

CREBBP EP300

2.95e-06335214716005
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

2.95e-06335218070920
Pubmed

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.

CREBBP EP300

2.95e-06335221967847
Pubmed

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.

CREBBP EP300

2.95e-06335219252086
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

CREBBP EP300

2.95e-06335227903646
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

2.95e-06335212748286
Pubmed

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.

CREBBP EP300

2.95e-06335210075656
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

2.95e-06335224340053
Pubmed

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.

CREBBP EP300

2.95e-06335219273602
Pubmed

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

CREBBP EP300

2.95e-06335215649887
Pubmed

Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.

CREBBP EP300

2.95e-06335222179676
Pubmed

CBP/p300 are bimodal regulators of Wnt signaling.

CREBBP EP300

2.95e-06335217410209
Pubmed

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

CREBBP EP300

2.95e-06335226951377
Pubmed

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CREBBP EP300

2.95e-06335221789216
Pubmed

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.

CREBBP EP300

2.95e-06335212050117
Pubmed

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

CREBBP EP300

2.95e-06335216237459
Pubmed

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

CREBBP EP300

2.95e-06335212384703
Pubmed

Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.

CREBBP EP300

2.95e-06335210350644
Pubmed

Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.

CREBBP EP300

2.95e-06335229145650
Pubmed

Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.

CREBBP EP300

2.95e-0633527870179
Pubmed

The IFNgamma-induced STAT1-CBP/P300 association, required for a normal response to the cytokine, is disrupted in Brucella-infected macrophages.

CREBBP EP300

2.95e-06335219041714
Pubmed

Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.

CREBBP EP300

2.95e-06335212776737
Pubmed

Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage.

CREBBP EP300

2.95e-06335230836930
Pubmed

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.

CREBBP EP300

2.95e-06335214759370
Pubmed

Activation of Smad1-mediated transcription by p300/CBP.

CREBBP EP300

2.95e-06335210673036
Pubmed

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

CREBBP EP300

2.95e-06335212456660
Pubmed

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.

CREBBP EP300

2.95e-06335222474372
Pubmed

Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

CREBBP EP300

2.95e-0633529488451
Pubmed

Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression.

CREBBP EP300

2.95e-06335215782138
Pubmed

Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort.

CREBBP EP300

2.95e-06335228302137
Pubmed

Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.

CREBBP EP300

2.95e-06335228831000
Pubmed

CREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleus.

CREBBP EP300

2.95e-06335210893273
Pubmed

p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint.

CREBBP EP300

2.95e-06335217272271
InteractionSMAD1 interactions

COL3A1 ZNF8 PRDM16 CREBBP ANKRD27 EP300

2.93e-06243346int:SMAD1
InteractionMAML2 interactions

CREBBP EP300 NOTCH4

2.94e-0617343int:MAML2
InteractionSMAD2 interactions

COL3A1 ZNF8 RNF123 PRDM16 CREBBP EP300 NOTCH4

3.03e-06385347int:SMAD2
InteractionZBTB17 interactions

ZNF8 PRDM5 CREBBP EP300

8.37e-0677344int:ZBTB17
InteractionNTN5 interactions

FBN1 LRP1B VWDE

8.67e-0624343int:NTN5
InteractionHOXB2 interactions

PRDM16 CREBBP EP300

3.02e-0536343int:HOXB2
InteractionZDHHC15 interactions

NFXL1 LRP12 THBS1 FBN1

5.66e-05125344int:ZDHHC15
InteractionHDAC1 interactions

ZNF8 CHD1 RNF123 PRDM5 ZFYVE1 PRDM16 REPIN1 CREBBP EP300

6.68e-051108349int:HDAC1
InteractionSMAD3 interactions

COL3A1 ZNF8 PRDM16 CREBBP EP300 NOTCH4

9.14e-05447346int:SMAD3
InteractionITGAE interactions

TRIM54 RNF123

9.87e-059342int:ITGAE
InteractionHOXB3 interactions

CREBBP EP300

9.87e-059342int:HOXB3
InteractionARGFX interactions

CREBBP EP300

9.87e-059342int:ARGFX
InteractionBCL3 interactions

RNF123 CREBBP EP300

1.14e-0456343int:BCL3
InteractionCHRDL1 interactions

LRP1B CREBBP

1.51e-0411342int:CHRDL1
InteractionHRG interactions

THBS1 FBN1 LRP1B

1.63e-0463343int:HRG
InteractionZNF672 interactions

REPIN1 LIN28A

1.80e-0412342int:ZNF672
InteractionFBLN2 interactions

ZNF8 FBN1 VWDE

1.87e-0466343int:FBLN2
InteractionZNF8 interactions

ZNF8 PRDM5 LRP1B

2.22e-0470343int:ZNF8
InteractionSMAD4 interactions

COL3A1 ZNF8 PRDM16 CREBBP EP300 NOTCH4

2.31e-04530346int:SMAD4
InteractionRNASE4 interactions

LRP1B VWDE

2.48e-0414342int:RNASE4
InteractionPROK2 interactions

LRP1B VWDE

2.48e-0414342int:PROK2
InteractionMAML1 interactions

CREBBP EP300 NOTCH4

2.52e-0473343int:MAML1
InteractionTGS1 interactions

CREBBP LIN28A EP300

2.73e-0475343int:TGS1
InteractionIGFL3 interactions

LRP12 LRP1B VWDE

2.73e-0475343int:IGFL3
InteractionKLF2 interactions

CREBBP EP300

2.86e-0415342int:KLF2
InteractionHSF2 interactions

TRIM54 CREBBP EP300

3.18e-0479343int:HSF2
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A5 SPATA31A7

1.58e-058352chr9q12
Cytoband9p13.1

SPATA31A1 SPATA31A3

1.54e-04243529p13.1
GeneFamilyLow density lipoprotein receptors

LRP12 LRP1B

9.00e-0513202634
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.57e-0417202486
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM5 PRDM16

1.57e-04172021197
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.76e-041820291
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF449 ZNF8 PRDM5 PRDM16 REPIN1

9.18e-0471820528
GeneFamilyRing finger proteins

TRIM54 RNF123 TRIM61

3.28e-0327520358
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM54 TRIM61

4.88e-039520259
GeneFamilyAnkyrin repeat domain containing

ANKRD27 NOTCH4

2.89e-02242202403
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NFXL1 THBS1 PRDM16 LRP1B

1.34e-0518635423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1 FBN1

1.43e-051893542a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1 FBN1

1.49e-05191354b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1 FBN1

1.52e-051923546f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1 FBN1

1.52e-051923543d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1 FBN1

1.52e-05192354ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1 FBN1

1.58e-051943546e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3|TCGA-Stomach / Sample_Type by Project: Shred V9

COL3A1 THBS1 PRKD1 FBN1

1.58e-051943542260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1 FBN1

1.58e-0519435489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 CHD1 HECA EP300

1.65e-0519635401cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

COL3A1 THBS1 PRKD1 FBN1

1.68e-05197354f1c8936986123a3151140c374fcd62d6705c530b
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

COL3A1 THBS1 PRKD1 FBN1

1.68e-05197354fb847f2277609c31fffcdf49517243ce0684facf
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

COL3A1 THBS1 PRKD1 FBN1

1.71e-05198354df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL3A1 THBS1 PRKD1 FBN1

1.75e-0519935430d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 THBS1 PRKD1 FBN1

1.78e-052003549b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 THBS1 PRKD1 FBN1

1.78e-05200354b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL3A1 THBS1 PRKD1 FBN1

1.78e-0520035450ca6550998e461ef26dd670351060bd940765a8
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

COL3A1 THBS1 PRKD1 FBN1

1.78e-05200354a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

COL3A1 THBS1 FBN1

1.58e-04134353a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

COL3A1 THBS1 FBN1

1.58e-041343539458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 PRDM16 LRP1B

2.16e-041493537e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 PRDM16 LRP1B

2.16e-04149353b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

FBN1 ZFYVE1 ANKRD27

2.61e-0415935355e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 TMEM184C THBS1

2.76e-041623533f264263878af630921911c2b344ac56eb1e7099
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL3A1 TRIM54 VWDE

3.01e-04167353cb650f74306fa0d9f4bf49890b73065d193b94dc
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

COL3A1 THBS1 FBN1

3.07e-04168353aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

3.12e-04169353849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL3A1 TMEM184C PRDM5

3.17e-041703538465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RNF123 ANKRD27 NOTCH4

3.28e-04172353a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

3.45e-04175353e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

FBN1 HECA NOTCH4

3.45e-0417535316849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

3.51e-04176353f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellASK452-Endothelial-Lymphatic|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

ZNF449 TMEM184C PRKD1

3.51e-04176353b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL3A1 FBN1 LRP1B

3.51e-041763532e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

COL3A1 FBN1 LRP1B

3.51e-04176353f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

3.51e-04176353fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

COL3A1 THBS1 FBN1

3.63e-04178353142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF449 COL3A1 FBN1

3.81e-041813530ec9621a078d004bbd25a587757d24b5cf162959
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF449 COL3A1 FBN1

3.81e-04181353c7f5aedcb74c21fb587a95a16d700e2a38a380ee
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

PRKD1 PRDM16 REPIN1

3.81e-04181353cc7ae1221a28bc404138a7efee0ad08a19cc3d86
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 FBN1 PRDM5

3.87e-04182353dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 CHD1 EP300

3.87e-04182353f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 FBN1 PRDM5

3.87e-04182353c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

3.87e-04182353f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRIM54 THBS1 PRDM16

3.94e-041833532902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 CHD1 EP300

4.00e-041843531154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.00e-04184353e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 CHD1 EP300

4.06e-041853537adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 FBN1 MUC13

4.06e-04185353d5f5866924648a3c14e2596218fd548a31777aa3
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.13e-0418635335c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.13e-04186353d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 FBN1 PRDM5

4.13e-04186353827f2f2ddde315d1e5970dd56f906c555ec699af
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TRMT1L CREBBP EP300

4.13e-0418635303db813598b67b1e08f759758a1c2023396921fa
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL3A1 THBS1 FBN1

4.13e-041863535473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.19e-041873537ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

COL3A1 THBS1 PRKD1

4.19e-04187353464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

PRKD1 PRDM16 LRP1B

4.19e-041873532ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL3A1 FBN1 ANKRD27

4.26e-0418835314bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 THBS1 FBN1

4.26e-04188353b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellP15-Mesenchymal|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL3A1 THBS1 FBN1

4.26e-04188353f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.26e-041883532ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.26e-041883533cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

TMEM184C THBS1 CHD1

4.33e-041893533922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.33e-04189353f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

THBS1 CHD1 FBN1

4.33e-0418935346e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 MUC13 NOTCH4

4.33e-04189353b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.33e-04189353562f8bf5a7d38afb4a8f2415d617d5f79cfb7e3f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 PRKD1 FBN1

4.33e-04189353a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 FBN1

4.33e-04189353e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL3A1 THBS1 FBN1

4.33e-041893530c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

THBS1 CHD1 FBN1

4.33e-04189353b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.33e-04189353270dd4a0fc5260288fe6829837942c78b40ecec4
ToppCelldroplet-Limb_Muscle|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.39e-0419035306c2b13fa88abbcb8086f13b8d98a156e41e4198
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL3A1 THBS1 FBN1

4.39e-041903530fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

COL3A1 THBS1 FBN1

4.39e-041903533a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 PRDM16 NOTCH4

4.39e-04190353aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.39e-041903533dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.39e-04190353b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

TRIM54 THBS1 PRDM16

4.39e-041903533729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 PRKD1

4.39e-04190353d60395739458d7f47a3350ade751fe3819500320
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.39e-04190353cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

COL3A1 THBS1 FBN1

4.46e-041913539bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 THBS1 FBN1

4.46e-041913535c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3|TCGA-Ovary / Sample_Type by Project: Shred V9

COL3A1 THBS1 FBN1

4.46e-0419135380d30d8eedb4c70b58440646325bc04c5700803e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRKD1 PRDM16 LRP1B

4.46e-04191353963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 PRDM16 NOTCH4

4.46e-041913534b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.46e-04191353b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.46e-041913531b26056df078674f37a6c06f6256b30cfcec21a7
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL3A1 THBS1 FBN1

4.46e-0419135380484d39f34703a33b9bac09826b7a526e883cab
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL3A1 PRKD1 FBN1

4.46e-041913536688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL3A1 PRKD1 FBN1

4.53e-0419235399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 PRKD1 FBN1

4.53e-04192353dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 FBN1

4.53e-04192353162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.53e-04192353ac1477433704573f95111eee6263b93668d2845e
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.53e-04192353671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 FBN1

4.53e-041923534e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.53e-04192353840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL3A1 THBS1 FBN1

4.53e-041923539333aba0d04203ccccad78d82bf6359922f810a7
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL3A1 THBS1 FBN1

4.53e-041923538937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL3A1 THBS1 FBN1

4.53e-04192353f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
DiseaseMenke-Hennekam syndrome

CREBBP EP300

8.68e-072282cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

8.68e-072282DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

8.68e-072282cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

8.68e-072282C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

8.68e-072282DOID:1933 (is_implicated_in)
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

8.68e-072282180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

8.68e-072282cv:C4551859
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

8.68e-072282C0035934
Diseasesystemic scleroderma (implicated_via_orthology)

COL3A1 FBN1

2.60e-063282DOID:418 (implicated_via_orthology)
DiseaseFamilial aortopathy

COL3A1 FBN1

2.60e-063282cv:CN078214
DiseaseSquamous cell carcinoma of esophagus

FAT2 CREBBP EP300

9.99e-0595283C0279626
Diseaseheart disease (biomarker_via_orthology)

THBS1 EP300

1.17e-0417282DOID:114 (biomarker_via_orthology)
DiseaseLiver Cirrhosis

COL3A1 THBS1 FBN1

1.27e-04103283C0023890
DiseaseFibrosis, Liver

COL3A1 THBS1 FBN1

1.34e-04105283C0239946
DiseaseSquamous cell carcinoma

CREBBP EP300 NOTCH4

2.20e-04124283C0007137
Diseasesystemic scleroderma (is_implicated_in)

FBN1 NOTCH4

2.37e-0424282DOID:418 (is_implicated_in)
DiseaseEndogenous Hyperinsulinism

COL3A1 FBN1

2.78e-0426282C1257963
DiseaseExogenous Hyperinsulinism

COL3A1 FBN1

2.78e-0426282C1257964
DiseaseCompensatory Hyperinsulinemia

COL3A1 FBN1

2.78e-0426282C1257965
DiseaseHyperinsulinism

COL3A1 FBN1

3.23e-0428282C0020459
DiseaseHyperglycemia, Postprandial

COL3A1 FBN1

3.72e-0430282C1855520
DiseaseHyperglycemia

COL3A1 FBN1

3.72e-0430282C0020456
Diseasemyocardial infarction (biomarker_via_orthology)

COL3A1 THBS1 PRKD1

4.64e-04160283DOID:5844 (biomarker_via_orthology)
DiseaseCarcinoma, Transitional Cell

CREBBP EP300

6.96e-0441282C0007138

Protein segments in the cluster

PeptideGeneStartEntry
AKDQQKHFPPLCCCP

TMEM184C

146

Q9NVA4
CQENKCPVPFCLNIK

EP300

1796

Q09472
KHCQENKCPVPFCLN

CREBBP

1831

Q92793
KKCCNHCYLIKPPDN

CHD1

756

O14646
NPNRPLAECQFCHKK

PRDM5

596

Q9NQX1
CHPLCQCPKCAPAQK

ANKRD27

711

Q96NW4
FNCHKRCAPKVPNNC

PRKD1

306

Q15139
CQPGNFHCKNNRCVF

LRP12

451

Q9Y561
CGPHEFQCKNNNCIP

LRP1B

3476

Q9NZR2
KHSKCCPAKGNQCCP

SMCP

6

P49901
KGSQCCPPKHNHCCQ

SMCP

46

P49901
NHCCQPKPPCCIQAR

SMCP

56

P49901
KNQCPKELPCGHRCK

NFXL1

766

Q6ZNB6
PCCQARLNCKHCGKP

HECA

486

Q9UBI9
VCKCPPQFSGKHCEQ

FAT2

3971

Q9NYQ8
NECNQAPKPCNFICK

FBN1

2446

P35555
KNPARNCRDLKFCHP

COL3A1

1256

P02461
CPLCPKEKFRACNSH

TRMT1L

121

Q7Z2T5
HKQKFQAPVCGFPCN

SPATA31A6

1231

Q5VVP1
KPFKCHLCNRCFGQQ

PRDM16

1006

Q9HAZ2
KQKFQAPVCGFPCNH

SPATA31A7

1236

Q8IWB4
DCACHKGNRNCPIQK

SETD5

401

Q9C0A6
DLCAQKPCPRNSHCL

NOTCH4

846

Q99466
FQCACCGKRFRHKPN

REPIN1

236

Q9BWE0
KQKFQAPVCGFPCNH

SPATA31A3

1236

Q5VYP0
CHFCCPERKFISNPQ

TRIM61

56

Q5EBN2
PCQHNLCRKCANDVF

TRIM54

41

Q9BYV2
NHGKCIKPNICQCLP

VWDE

1336

Q8N2E2
HATANKQVCKPRNPC

THBS1

636

P07996
KCPDACNAQHKQCLI

MUC13

366

Q9H3R2
KQKFQAPVCGFPCNH

SPATA31A1

1236

Q5TZJ5
KQKFQAPVCGFPCNH

SPATA31A5

1236

Q5VU36
FQPCGHKSCKACINQ

RNF123

1266

Q5XPI4
DHPVRVCFNCNKKPG

ZFYVE1

761

Q9HBF4
HRSDRPFKCNQCGKC

ZNF8

461

P17098
KPHRCPQCGKCFARK

ZNF449

321

Q6P9G9
ECKLPPQPKKCHFCQ

LIN28A

151

Q9H9Z2