Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA2D1 CACNA1G

5.87e-055492GO:0086007
GeneOntologyMolecularFunctioncalcium channel activity

CACNA2D1 TRPV4 TRPV3 CACNA1G

2.81e-04129494GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA2D1 TRPV4 TRPV3 CACNA1G

5.11e-04151494GO:0015085
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

FLNA CACNA2D1 PTPRC SRI TRPV4 TRPV3 CACNA1G TRDN

4.11e-08217498GO:0097553
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

FLNA CACNA2D1 SRI CACNA1G TRDN

2.79e-0759495GO:0086065
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN

3.10e-07392499GO:0070588
GeneOntologyBiologicalProcesspositive regulation of transport

FLNA CACNA2D1 PTPRC UBR5 ANO6 TM9SF4 SRI TENM1 TRPV3 CACNA1G MMP13 TRDN CNTN1

9.42e-0710814913GO:0051050
GeneOntologyBiologicalProcesscalcium ion transport

FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN

2.70e-06509499GO:0006816
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transport

FLNA CACNA2D1 ANO6 SRI TRPV3 TRDN CNTN1

2.97e-06266497GO:0043270
GeneOntologyBiologicalProcesscardiac conduction

FLNA CACNA2D1 SRI CACNA1G TRDN

3.90e-06100495GO:0061337
GeneOntologyBiologicalProcessmuscle contraction

FLNA CACNA2D1 SULF2 SRI TRPV4 CACNA1G NR4A1 TRDN

4.20e-06400498GO:0006936
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA2D1 TRPV4 TRPV3 CACNA1G

5.06e-0648494GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA2D1 TRPV4 TRPV3 CACNA1G

5.06e-0648494GO:1902656
GeneOntologyBiologicalProcessstriated muscle contraction

FLNA CACNA2D1 SRI TRPV4 CACNA1G NR4A1

1.21e-05217496GO:0006941
GeneOntologyBiologicalProcessmetal ion transport

SLC6A12 FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN CNTN1

1.76e-0510004911GO:0030001
GeneOntologyBiologicalProcessregulation of metal ion transport

FLNA CACNA2D1 ANO6 SRI TRPV3 CACNA1G TRDN CNTN1

1.92e-05493498GO:0010959
GeneOntologyBiologicalProcessimport into cell

DOCK1 SLC6A12 CACNA2D1 LRP12 PTPRC ANO6 TM9SF4 SCARB2 TRPV4 TRPV3 CACNA1G

3.40e-0510744911GO:0098657
GeneOntologyBiologicalProcessmuscle system process

FLNA CACNA2D1 SULF2 SRI TRPV4 CACNA1G NR4A1 TRDN

4.02e-05547498GO:0003012
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC6A12 FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN

5.09e-059224910GO:0098662
GeneOntologyBiologicalProcesspositive regulation of cation transmembrane transport

FLNA CACNA2D1 ANO6 SRI TRDN

5.70e-05174495GO:1904064
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

FLNA CACNA2D1 ANO6 SRI TRPV3 CACNA1G TRDN CNTN1

5.86e-05577498GO:0043269
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A12 FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN

6.10e-059424910GO:0098655
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

FLNA SLF1 PTPRC ANO6 ENPP2 SCARB2 PLXNA4 TENM1 TRPV4 DDHD2 CDC34 CNTN1

6.31e-0513664912GO:0051130
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC6A12 FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN CNTN1

6.70e-0511574911GO:0006812
GeneOntologyBiologicalProcesscardiac muscle cell contraction

FLNA CACNA2D1 SRI CACNA1G

7.03e-0593494GO:0086003
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

FLNA CACNA2D1 CACNA1G

7.16e-0534493GO:0086019
GeneOntologyBiologicalProcesscalcium ion import

CACNA2D1 TRPV4 TRPV3 CACNA1G

8.62e-0598494GO:0070509
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transmembrane transport

FLNA CACNA2D1 ANO6 SRI TRDN

9.07e-05192495GO:0034767
GeneOntologyBiologicalProcesspositive regulation of protein transport

FLNA UBR5 TM9SF4 SRI TENM1 MMP13

1.04e-04319496GO:0051222
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC6A12 FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN

1.15e-0410174910GO:0098660
GeneOntologyBiologicalProcesscell volume homeostasis

SLC6A12 ANO6 TRPV4

1.36e-0442493GO:0006884
GeneOntologyBiologicalProcesspositive regulation of intracellular protein transport

FLNA UBR5 TM9SF4 TENM1

1.66e-04116494GO:0090316
GeneOntologyBiologicalProcesspositive regulation of substrate adhesion-dependent cell spreading

DOCK1 FLNA ENPP2

1.78e-0446493GO:1900026
GeneOntologyBiologicalProcessactin-mediated cell contraction

FLNA CACNA2D1 SRI CACNA1G

2.34e-04127494GO:0070252
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A12 FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN

2.44e-0411154910GO:0034220
GeneOntologyBiologicalProcessnegative regulation of ryanodine-sensitive calcium-release channel activity

SRI TRDN

3.00e-0411492GO:0060315
GeneOntologyBiologicalProcessregulation of membrane repolarization during action potential

FLNA CACNA2D1

3.00e-0411492GO:0098903
GeneOntologyBiologicalProcessmembrane lipid catabolic process

ENPP2 SCARB2 FUCA1

3.03e-0455493GO:0046466
GeneOntologyBiologicalProcessregulation of heart contraction

FLNA CACNA2D1 SRI CACNA1G TRDN

3.04e-04249495GO:0008016
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC6A12 FLNA CACNA2D1 PTPRC ANO6 SRI TRPV4 TRPV3 CACNA1G TRDN CNTN1

3.05e-0413744911GO:0006811
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA2D1 TRPV4 TRPV3 CACNA1G

3.59e-04142494GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA2D1 TRPV4 TRPV3 CACNA1G

3.59e-04142494GO:0098659
GeneOntologyBiologicalProcessregulation of cell communication by electrical coupling involved in cardiac conduction

SRI TRDN

3.59e-0412492GO:1901844
GeneOntologyBiologicalProcessmaintenance of location in cell

FLNA PTPRC SRI VPS13A TRDN

3.65e-04259495GO:0051651
GeneOntologyBiologicalProcesspositive regulation of establishment of protein localization

FLNA UBR5 TM9SF4 SRI TENM1 MMP13

3.68e-04403496GO:1904951
GeneOntologyBiologicalProcessbone development

SULF2 PTPRC ANO6 TRPV4 MMP13

3.98e-04264495GO:0060348
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

FLNA PTPRC SRI TRDN

3.99e-04146494GO:0051209
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

FLNA PTPRC SRI TRDN

4.09e-04147494GO:0051283
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

FLNA PTPRC SRI TRDN

4.30e-04149494GO:0051282
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

FLNA CACNA2D1 CACNA1G

4.32e-0462493GO:0086002
GeneOntologyBiologicalProcesspositive regulation of transmembrane transport

FLNA CACNA2D1 ANO6 SRI TRDN

4.64e-04273495GO:0034764
GeneOntologyBiologicalProcesssequestering of calcium ion

FLNA PTPRC SRI TRDN

4.76e-04153494GO:0051208
GeneOntologyBiologicalProcessactin filament-based movement

FLNA CACNA2D1 SRI CACNA1G

4.76e-04153494GO:0030048
GeneOntologyBiologicalProcesspositive regulation of calcium ion transport

CACNA2D1 SRI TRPV3 TRDN

4.88e-04154494GO:0051928
GeneOntologyBiologicalProcessregulation of substrate adhesion-dependent cell spreading

DOCK1 FLNA ENPP2

5.19e-0466493GO:1900024
GeneOntologyBiologicalProcessskeletal system development

SULF2 PTPRC ANO6 TRPS1 HAPLN2 TRPV4 MMP13

5.86e-04615497GO:0001501
GeneOntologyBiologicalProcesspositive regulation of intracellular transport

FLNA UBR5 TM9SF4 TENM1

5.90e-04162494GO:0032388
GeneOntologyBiologicalProcessglycerolipid catabolic process

PLA2G4B ENPP2 DDHD2

6.17e-0470493GO:0046503
GeneOntologyBiologicalProcessregulation of high voltage-gated calcium channel activity

CACNA2D1 SRI

6.49e-0416492GO:1901841
GeneOntologyBiologicalProcesscardiac muscle contraction

FLNA CACNA2D1 SRI CACNA1G

6.61e-04167494GO:0060048
GeneOntologyBiologicalProcessresponse to hormone

ACOD1 ZNF536 PTPRC UBR5 RXFP2 TRPV4 RXFP1 NR4A1 MMP13

6.85e-041042499GO:0009725
GeneOntologyBiologicalProcessheart contraction

FLNA CACNA2D1 SRI CACNA1G TRDN

6.90e-04298495GO:0060047
GeneOntologyBiologicalProcessnegative regulation of release of sequestered calcium ion into cytosol

SRI TRDN

7.35e-0417492GO:0051280
GeneOntologyBiologicalProcessheart process

FLNA CACNA2D1 SRI CACNA1G TRDN

8.12e-04309495GO:0003015
GeneOntologyBiologicalProcessregulation of cell communication by electrical coupling

SRI TRDN

8.26e-0418492GO:0010649
GeneOntologyBiologicalProcessregulation of intracellular protein transport

FLNA UBR5 TM9SF4 TENM1

9.12e-04182494GO:0033157
GeneOntologyBiologicalProcesspositive regulation of sequestering of calcium ion

SRI TRDN

9.21e-0419492GO:0051284
GeneOntologyBiologicalProcessregulation of calcium ion transport

CACNA2D1 SRI TRPV3 CACNA1G TRDN

9.90e-04323495GO:0051924
GeneOntologyBiologicalProcessregulation of blood circulation

FLNA CACNA2D1 SRI CACNA1G TRDN

1.03e-03326495GO:1903522
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

FLNA ENPP2 SCARB2 PLXNA4 TENM1 CNTN1

1.07e-03494496GO:0031346
GeneOntologyBiologicalProcesscardiac muscle cell action potential

FLNA CACNA2D1 CACNA1G

1.16e-0387493GO:0086001
GeneOntologyBiologicalProcessparturition

PLA2G4B RXFP1

1.24e-0322492GO:0007567
GeneOntologyBiologicalProcesscytoplasmic sequestering of protein

FLNA SRI

1.24e-0322492GO:0051220
GeneOntologyBiologicalProcessconnective tissue development

SULF2 TRPS1 TRPV4 RXFP1 MMP13

1.29e-03343495GO:0061448
GeneOntologyBiologicalProcessaction potential

FLNA CACNA2D1 SRI CACNA1G

1.32e-03201494GO:0001508
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

CACNA2D1 CACNA1G

1.35e-0323492GO:0086012
GeneOntologyBiologicalProcessregulation of calcium ion transmembrane transporter activity

CACNA2D1 SRI TRDN

1.36e-0392493GO:1901019
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

FLNA PTPRC SRI TRPV4 TRDN

1.58e-03359495GO:0006874
GeneOntologyBiologicalProcessregulation of system process

FLNA CACNA2D1 SRI TRPV4 CACNA1G NR4A1 TRDN

1.64e-03734497GO:0044057
GeneOntologyBiologicalProcessregulation of ryanodine-sensitive calcium-release channel activity

SRI TRDN

1.73e-0326492GO:0060314
GeneOntologyBiologicalProcesscell communication by electrical coupling involved in cardiac conduction

SRI TRDN

1.73e-0326492GO:0086064
GeneOntologyBiologicalProcessglycolipid catabolic process

SCARB2 FUCA1

1.87e-0327492GO:0019377
GeneOntologyBiologicalProcessextracellular matrix organization

SULF2 HAPLN2 RXFP1 MMP13 P3H4

1.96e-03377495GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

SULF2 HAPLN2 RXFP1 MMP13 P3H4

1.98e-03378495GO:0043062
GeneOntologyBiologicalProcessregulation of cell size

SLC6A12 ANO6 PLXNA4 TRPV4

1.99e-03225494GO:0008361
GeneOntologyBiologicalProcessexternal encapsulating structure organization

SULF2 HAPLN2 RXFP1 MMP13 P3H4

2.00e-03379495GO:0045229
GeneOntologyBiologicalProcessregulation of membrane potential

FLNA CACNA2D1 ANO6 SRI CACNA1G TRDN

2.01e-03559496GO:0042391
GeneOntologyBiologicalProcesscellular homeostasis

SLC6A12 FLNA PTPRC ANO6 TM9SF4 SRI TRPV4 TRDN

2.02e-03981498GO:0019725
GeneOntologyBiologicalProcessregulation of protein transport

FLNA UBR5 TM9SF4 SRI TENM1 MMP13

2.02e-03560496GO:0051223
GeneOntologyBiologicalProcessregulation of monoatomic cation transmembrane transport

FLNA CACNA2D1 ANO6 SRI TRDN

2.03e-03380495GO:1904062
GeneOntologyBiologicalProcesslipid catabolic process

PLA2G4B ENPP2 SCARB2 FUCA1 DDHD2

2.07e-03382495GO:0016042
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA2D1 TRPV4 TRPV3 CACNA1G

2.15e-03230494GO:0098739
GeneOntologyBiologicalProcesssubstrate adhesion-dependent cell spreading

DOCK1 FLNA ENPP2

2.22e-03109493GO:0034446
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport

CACNA2D1 SRI TRDN

2.22e-03109493GO:1904427
GeneOntologyBiologicalProcesscalcium ion homeostasis

FLNA PTPRC SRI TRPV4 TRDN

2.24e-03389495GO:0055074
GeneOntologyBiologicalProcessregulation of cardiac muscle cell membrane repolarization

FLNA CACNA2D1

2.30e-0330492GO:0099623
GeneOntologyBiologicalProcesspositive regulation of humoral immune response

ACOD1 PTPRC

2.30e-0330492GO:0002922
GeneOntologyBiologicalProcessregulation of striated muscle contraction

SRI TRPV4 NR4A1

2.33e-03111493GO:0006942
GeneOntologyCellularComponentSet3 complex

SETD5 KMT2E

5.38e-062492GO:0034967
GeneOntologyCellularComponentRpd3L-Expanded complex

SETD5 KMT2E

5.38e-062492GO:0070210
DomainRelaxin_rcpt

RXFP2 RXFP1

6.47e-062482IPR008112
DomainTRPV1-4_channel

TRPV4 TRPV3

3.87e-054482IPR008347
DomainLDLR_class-A_CS

LRP12 RXFP2 RXFP1

1.47e-0440483IPR023415
DomainLdl_recept_a

LRP12 RXFP2 RXFP1

2.10e-0445483PF00057
Domain-

LRP12 RXFP2 RXFP1

2.24e-04464834.10.400.10
DomainLDLRA_1

LRP12 RXFP2 RXFP1

2.54e-0448483PS01209
DomainLDLRA_2

LRP12 RXFP2 RXFP1

2.70e-0449483PS50068
DomainLDrepeatLR_classA_rpt

LRP12 RXFP2 RXFP1

2.70e-0449483IPR002172
DomainLDLa

LRP12 RXFP2 RXFP1

2.70e-0449483SM00192
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH5

5.77e-0414482IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH5

5.77e-0414482IPR013602
DomainDHC_N2

DNAH12 DNAH5

5.77e-0414482PF08393
DomainAAA_8

DNAH12 DNAH5

5.77e-0414482PF12780
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH5

5.77e-0414482IPR011704
DomainAAA_5

DNAH12 DNAH5

5.77e-0414482PF07728
DomainDHC_fam

DNAH12 DNAH5

6.65e-0415482IPR026983
DomainDynein_heavy_dom

DNAH12 DNAH5

6.65e-0415482IPR004273
DomainDynein_heavy

DNAH12 DNAH5

6.65e-0415482PF03028
DomainAlkaline_phosphatase_core

SULF2 ENPP2

2.87e-0331482IPR017850
DomainAlkaline_Pase-like_a/b/a

SULF2 ENPP2

2.87e-0331482IPR017849
Domain-

SULF2 ENPP2

2.87e-03314823.40.720.10
DomainIon_trans_dom

TRPV4 TRPV3 CACNA1G

3.14e-03114483IPR005821
DomainIon_trans

TRPV4 TRPV3 CACNA1G

3.14e-03114483PF00520
DomainSET

SETD5 KMT2E

4.98e-0341482PF00856
DomainSET

SETD5 KMT2E

6.23e-0346482SM00317
DomainSET_dom

SETD5 KMT2E

7.32e-0350482IPR001214
DomainSET

SETD5 KMT2E

7.32e-0350482PS50280
Domain-

TRPS1 NR4A1

9.43e-03574823.30.50.10
DomainZnf_NHR/GATA

TRPS1 NR4A1

9.76e-0358482IPR013088
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO6 SRI TRPV4 TRPV3 TRDN

5.63e-0699375MM14910
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO6 SRI TRPV4 TRPV3 TRDN

7.87e-06106375M27200
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO6 SRI TRPV4 TRPV3 TRDN

9.04e-05176375MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO6 SRI TRPV4 TRPV3 TRDN

1.09e-04183375M997
PathwayREACTOME_RELAXIN_RECEPTORS

RXFP2 RXFP1

1.86e-048372M27371
PathwayREACTOME_RELAXIN_RECEPTORS

RXFP2 RXFP1

2.98e-0410372MM15111
PathwayWP_MAPK_SIGNALING

FLNA CACNA2D1 PLA2G4B CACNA1G NR4A1

4.29e-04246375M39597
PathwayKEGG_MAPK_SIGNALING_PATHWAY

FLNA CACNA2D1 PLA2G4B CACNA1G NR4A1

6.23e-04267375M10792
Pubmed

The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.

TRPV4 TRPV3

2.03e-06250225351988
Pubmed

Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4.

TRPV4 TRPV3

2.03e-06250219164517
Pubmed

TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation.

TRPV4 TRPV3

2.03e-06250221586160
Pubmed

Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice.

RXFP2 RXFP1

2.03e-06250222028476
Pubmed

Lactic acid induces transcriptional repression of macrophage inflammatory response via histone acetylation.

ACOD1 NR4A1

2.03e-06250238329873
Pubmed

Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity.

RXFP2 RXFP1

2.03e-06250216051677
Pubmed

Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium.

TRPV4 CACNA1G

2.03e-06250219617313
Pubmed

The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2.

RXFP2 RXFP1

2.03e-06250222973049
Pubmed

Warm temperatures activate TRPV4 in mouse 308 keratinocytes.

TRPV4 TRPV3

2.03e-06250212783886
Pubmed

Coassembly of Warm Temperature-Sensitive Transient Receptor Potential Vanilloid (TRPV) 3 and TRPV4 Channel Complexes with Distinct Functional Properties.

TRPV4 TRPV3

2.03e-06250235361697
Pubmed

Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function.

RXFP2 RXFP1

2.03e-06250219416161
Pubmed

Modeling the primary hormone-binding site of RXFP1 and RXFP2.

RXFP2 RXFP1

2.03e-06250219416162
Pubmed

TRPV3 and TRPV4 mediate warmth-evoked currents in primary mouse keratinocytes.

TRPV4 TRPV3

2.03e-06250215004014
Pubmed

Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.

RXFP2 RXFP1

2.03e-06250216963451
Pubmed

A novel role for relaxin-2 in the pathogenesis of primary varicosis.

RXFP2 RXFP1

6.07e-06350222737225
Pubmed

Role of DOCK2 and DOCK180 in fetal thymus colonization.

DOCK1 PTPRC

6.07e-06350219728314
Pubmed

PAR2 Mediates Itch via TRPV3 Signaling in Keratinocytes.

TRPV4 TRPV3

6.07e-06350232004565
Pubmed

Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins.

TRPV4 TRPV3

6.07e-06350229175331
Pubmed

Relaxin receptors 1 and 2 and nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) mRNAs are expressed in oral components of developing mice.

RXFP2 RXFP1

6.07e-06350224370181
Pubmed

The TRPV4 channel contributes to intercellular junction formation in keratinocytes.

TRPV4 TRPV3

6.07e-06350220413591
Pubmed

Increased expression of three types of transient receptor potential channels (TRPA1, TRPV4 and TRPV3) in burn scars with post-burn pruritus.

TRPV4 TRPV3

6.07e-06350224695993
Pubmed

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin.

RXFP2 RXFP1

6.07e-06350223024363
Pubmed

Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice.

TRPV4 TRPV3

6.07e-06350223536486
Pubmed

Activation of orphan receptors by the hormone relaxin.

RXFP2 RXFP1

6.07e-06350211809971
Pubmed

Structural Insights into the Unique Modes of Relaxin-Binding and Tethered-Agonist Mediated Activation of RXFP1 and RXFP2.

RXFP2 RXFP1

6.07e-06350234454945
Pubmed

Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.

RXFP2 RXFP1

6.07e-06350216411781
Pubmed

Regulation of Rxfp2 (Lgr8) expression in the mouse fetal kidney by the transcription factor Pod1 (Tcf 21).

RXFP2 RXFP1

6.07e-06350219416211
Pubmed

Receptors for relaxin family peptides.

RXFP2 RXFP1

1.21e-05450215956688
Pubmed

Nicotinic acid is a common regulator of heat-sensing TRPV1-4 ion channels.

TRPV4 TRPV3

1.21e-05450225752528
Pubmed

Low expression of CD39(+) /CD45RA(+) on regulatory T cells (Treg ) cells in type 1 diabetic children in contrast to high expression of CD101(+) /CD129(+) on Treg cells in children with coeliac disease.

PTPRC ENTPD1

1.21e-05450225421756
Pubmed

Quantitative Real-Time PCR detection of TRPV1-4 gene expression in human leukocytes from healthy and hyposensitive subjects.

TRPV4 TRPV3

1.21e-05450218983665
Pubmed

Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment.

RXFP2 RXFP1

1.21e-05450219279230
Pubmed

Expression of transient receptor potential vanilloid (TRPV) families 1, 2, 3 and 4 in the mouse olfactory epithelium.

TRPV4 TRPV3

1.21e-05450219839244
Pubmed

Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy.

TRPV4 TRPV3

1.21e-05450217521436
Pubmed

Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels.

NR4A1 MMP13

1.21e-05450220189954
Pubmed

A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability.

ENTPD1 TRPV4

1.21e-05450233653920
Pubmed

Dissecting domain-specific evolutionary pressure profiles of transient receptor potential vanilloid subfamily members 1 to 4.

TRPV4 TRPV3

1.21e-05450225333484
Pubmed

Functional expression of transient receptor potential vanilloid-related channels in chronically hypoxic human pulmonary arterial smooth muscle cells.

TRPV4 TRPV3

1.21e-05450218787888
Pubmed

International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.

RXFP2 RXFP1

1.21e-05450216507880
Pubmed

Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion.

ANO6 TRPV4

1.21e-05450235670667
Pubmed

TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

TRPV4 TRPV3

2.02e-05550212077606
Pubmed

H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.

RXFP2 RXFP1

2.02e-05550212506116
Pubmed

Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR7 and LGR8).

RXFP2 RXFP1

2.02e-05550215649866
Pubmed

The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors.

RXFP2 RXFP1

2.02e-05550218434306
Pubmed

RELAXIN enhances differentiation and matrix mineralization through Relaxin/insulin-like family peptide receptor 2 (Rxfp2) in MC3T3-E1 cells in vitro.

RXFP2 RXFP1

2.02e-05550224857857
Pubmed

Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior.

TRPV4 TRPV3

2.02e-05550230842533
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNA ZNF536 TCF20 UBR5 TRPS1 LRBA

2.96e-0541850634709266
Pubmed

Genetic targeting of relaxin and insulin-like factor 3 receptors in mice.

RXFP2 RXFP1

3.03e-05650215256493
Pubmed

ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system.

ATG4A LRBA

3.03e-05650233773106
Pubmed

ON-bipolar cell gene expression during retinal degeneration: Implications for optogenetic visual restoration.

SULF2 CNTN1

3.03e-05650233811915
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH12 DNAH5

4.23e-0575029256245
Pubmed

Relaxin induces matrix-metalloproteinases-9 and -13 via RXFP1: induction of MMP-9 involves the PI3K, ERK, Akt and PKC-ζ pathways.

RXFP2 RXFP1

4.23e-05750222835547
Pubmed

Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150.

TRPV4 TRPV3

4.23e-05750218701070
Pubmed

Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5.

PTPRC KMT2E

5.64e-05850218952892
Pubmed

Family-based association study for bipolar affective disorder.

TDRD9 TRDN

5.64e-05850220414141
Pubmed

Trps1 is necessary for normal temporomandibular joint development.

TRPS1 MMP13

9.05e-051050222427063
Pubmed

Tcf20 deficiency is associated with increased liver fibrogenesis and alterations in mitochondrial metabolism in mice and humans.

TCF20 MMP13

1.10e-041150237312667
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

FLNA ENTPD1 TRPS1 CACNA1G CNTN1

1.74e-0436350514691545
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DNAH5

1.82e-04145029373155
Pubmed

Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.

UBR5 MMP13

1.82e-041450228511701
Pubmed

Gene expression analysis of the embryonic subplate.

CACNA2D1 SULF2 TRPS1 PLXNA4

1.84e-0419650421862448
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

ZNF536 TCF20 TRPS1

2.37e-048350328794006
Pubmed

A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.

UBR5 CDC34

2.40e-041650222496338
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ZNF536 DNAH12 TCF20 TRPS1 VPS13A TRDN

2.98e-0463850631182584
Pubmed

Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract.

ACOD1 CDC34

3.05e-041850227695001
Pubmed

Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment.

ZNF536 PLXNA4

3.05e-041850224939585
Pubmed

Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia.

TRPV4 TRPV3

3.05e-041850231911949
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

DOCK1 FLNA UBR5 TRDN

3.67e-0423550430258100
Pubmed

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

TRPS1 MMP13

4.18e-042150229659575
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLNA CACNA2D1 UBR5 TM9SF4 SCARB2 SRI CDC34 P3H4

4.88e-04129750833545068
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPV4 TRPV3

5.48e-042450233884443
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

FLNA CACNA2D1 HPD ANO6 SCARB2 SRI FUCA1

5.94e-04101650719056867
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPV4 TRPV3

5.95e-042550216382100
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

SETD5 PLA2G4B ENTPD1 KMT2E MMP13 DNAH5

6.07e-0473050634857952
Pubmed

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.

UBR5 LRBA

6.44e-042650225228645
Pubmed

An introduction to TRP channels.

TRPV4 TRPV3

6.95e-042750216460286
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

ATG4A LRP12 TCF20

7.49e-0412350326912792
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

FLNA CACNA2D1 ANO6 SCARB2 SRI FUCA1 CNTN1

8.06e-04107050723533145
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

ZNF536 TENM1

9.17e-043150227798109
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPV4 TRPV3

1.04e-033350219834762
Pubmed

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.

CACNA2D1 ZNF536

1.04e-033350224159190
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

PLA2G4B ENPP2 ENTPD1 VPS13A TENM1

1.16e-0355250510737800
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

DOCK1 FLNA VPS13A LRBA

1.29e-0332950417474147
Pubmed

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

FLNA PTPRC ANO6 ENTPD1 SRI

1.29e-0356550520458337
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FLNA UBR5 ANO6 VPS13A LRBA

1.32e-0356850537774976
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

FLNA SETD5 TRPS1 DNAH5

1.33e-0333250437433992
Pubmed

Defining the membrane proteome of NK cells.

FLNA PTPRC UBR5 ANO6 SCARB2 ENTPD1 LRBA

1.34e-03116850719946888
GeneFamilyRelaxin family peptide receptors

RXFP2 RXFP1

2.31e-054362217
GeneFamilyDyneins, axonemal

DNAH12 DNAH5

5.14e-0417362536
GeneFamilyCalcium voltage-gated channel subunits

CACNA2D1 CACNA1G

1.22e-0326362253
GeneFamilyTransient receptor potential cation channels

TRPV4 TRPV3

1.41e-0328362249
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

FLNA CACNA2D1 RXFP2 TRPS1 PLXNA4 NR4A1 TRDN PCDH20

3.70e-06423478gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

FLNA CACNA2D1 SLF1 RXFP2 TRPS1 PLXNA4 CACNA1G NR4A1 TRDN PCDH20

1.11e-058314710gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500

DOCK1 CACNA2D1 ENPP2 ENTPD1 TRPS1 VPS13A CNTN1

2.34e-05393477gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 TRPS1 CACNA1G NR4A1

2.50e-05265476gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

DOCK1 CACNA2D1 TCF20 SETD5 TM9SF4 TRPS1 TENM1 RXFP1 CNTN1

6.53e-05818479DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000

LRP12 TRPS1 TENM1 RXFP1 PCDH20

1.48e-04229475gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

DOCK1 CACNA2D1 SETD5 TM9SF4 TRPS1 VPS13A

1.56e-04369476DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

CACNA2D1 SULF2 SCARB2 PLXNA4 CACNA1G NR4A1

1.65e-04373476gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

ATG4A CACNA2D1 LRP12 ZNF536 SULF2 ENPP2 ENTPD1 CACNA1G KMT2E P3H4

1.70e-0411484710facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#2_top-relative-expression-ranked_500

CACNA2D1 ENPP2 TRPS1

1.96e-0451473gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k2
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 ENPP2 TRPS1 PLXNA4 CACNA1G NR4A1

1.98e-04740478gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

CACNA2D1 ANO6 TRPS1 LRBA KMT2E

2.07e-04246475Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500

LRP12 ENPP2 TENM1 RXFP1 PCDH20

2.19e-04249475gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

CACNA2D1 ENPP2 TRPS1 SKIDA1 CACNA1G LRBA

2.34e-04398476gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 SLF1 RXFP2 TRPS1 CACNA1G NR4A1

2.54e-04768478gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000

ENPP2 ENTPD1 TRPS1 VPS13A TENM1 RXFP1 KMT2E PCDH20

2.56e-04769478gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

CACNA2D1 ZNF536 UBR5 HPD ANO6 TRPS1 VPS13A LRBA KMT2E

2.62e-04983479Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

DOCK1 CACNA2D1 SLF1 ENPP2 ENTPD1 TRPS1 VPS13A CNTN1

2.63e-04772478gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 SLF1 RXFP2 TRPS1 CACNA1G NR4A1

2.66e-04773478gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasMyeloid Cells, DC.103-11b+.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3

DOCK1 SULF2 ENTPD1 TRPS1 NR4A1 MMP13

2.71e-04409476GSM605823_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 RXFP2 TRPS1 PLXNA4 CACNA1G NR4A1

2.75e-04777478gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_top-relative-expression-ranked_1000

ATG4A FLNA CACNA2D1 ENPP2 SCARB2 ENTPD1 TRPV4 FUCA1

2.77e-04778478gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_1000
CoexpressionAtlasMyeloid Cells, DC.103-11b+.Lv, CD45+ CD11c+ MHC-II + CD11b high CD103-, Liver, avg-3

DOCK1 ACOD1 SULF2 ENTPD1 TRPS1 NR4A1

2.78e-04411476GSM538239_500
CoexpressionAtlasMyeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2

DOCK1 SULF2 ENTPD1 TRPS1 NR4A1 MMP13

2.89e-04414476GSM854271_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

FLNA SULF2 SLF1 RXFP2 TRPS1 PLXNA4 CACNA1G NR4A1

2.90e-04783478gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 SCARB2 RXFP2 PLXNA4 CACNA1G NR4A1

3.16e-04793478gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500

CACNA2D1 SETD5 TRPS1 TENM1 RXFP1 CNTN1

3.41e-04427476DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500

LRP12 ENPP2 ENTPD1 TENM1 RXFP1 PCDH20

3.46e-04428476gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_1000

LRP12 ENTPD1 TRPS1 TENM1 RXFP1 NR4A1 PCDH20 CNTN1

4.18e-04827478gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 TRPS1 PLXNA4 CACNA1G NR4A1 PCDH20

4.18e-04827478gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_200

PTPRC ENTPD1 MMP13 CNTN1

4.30e-04160474gudmap_developingKidney_e15.5_Podocyte cells_200
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#3_top-relative-expression-ranked_1000

CACNA2D1 ENTPD1 TRPS1 CNTN1

4.30e-04160474gudmap_developingKidney_e15.5_Podocyte cells_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_200

CACNA2D1 ENTPD1 TRPS1 CNTN1

4.72e-04164474gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

ATG4A FLNA CACNA2D1 ENPP2 ENTPD1 NR4A1

4.83e-04456476gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 RXFP2 CACNA1G

5.96e-04310475gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_200

CACNA2D1 TRPS1 RXFP1 CNTN1

6.43e-04178474DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_200
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000

ATG4A FLNA CACNA2D1 SCARB2

6.56e-04179474gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500

CACNA2D1 ZNF536 HPD ENTPD1 TRPS1 LRBA

7.20e-04492476Facebase_RNAseq_e10.5_Mandibular Arch_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

DOCK1 CACNA2D1 SETD5 TM9SF4 TRPS1

7.90e-04330475DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 RXFP2 CACNA1G

8.57e-04336475gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

FLNA CACNA2D1 SULF2 TRPS1 CACNA1G

8.68e-04337475gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_100

CACNA2D1 ENTPD1 CNTN1

8.84e-0485473gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1

CACNA2D1 ZNF536 SULF2 SETD5 ENPP2 ENTPD1 TRPS1 CACNA1G KMT2E

9.05e-041166479facebase_RNAseq_e14.5_palate_poster_distal_ERK2_WT_2500_K1
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#5_top-relative-expression-ranked_500

CACNA2D1 ENTPD1 CNTN1

9.14e-0486473gudmap_developingKidney_e15.5_Podocyte cells_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_1000

TCF20 TRPS1 TENM1 RXFP1

9.21e-04196474DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#4_top-relative-expression-ranked_500

CACNA2D1 ENTPD1 TRDN

1.08e-0391473gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k4
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

FLNA CACNA2D1 RXFP2 TRPS1 CACNA1G

1.08e-03354475gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

CACNA2D1 SULF2 RXFP2 PLXNA4 CACNA1G

1.18e-03361475gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasMyeloid Cells, DC.11cloSer.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-lo CD11b+, Small Intestine, avg-4

ACOD1 SULF2 ENTPD1 NR4A1 MMP13

1.22e-03364475GSM854276_500
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#1_top-relative-expression-ranked_200

CACNA2D1 CNTN1

1.28e-0324472gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500

TRPS1 TENM1 RXFP1 PCDH20

1.34e-03217474gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

ENPP2 TRPS1 TENM1 RXFP1 PCDH20

1.43e-03377475gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlasMyeloid Cells, DC.4+.Sp, CD11b CD45 CD4 CD11c CD8a, Spleen, avg-1

SLC6A12 SULF2 ENTPD1 TRPS1 NR4A1

1.51e-03382475GSM538248_500
ToppCellP03-Mesenchymal-myocytic_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA ZNF536 ENPP2 ENTPD1 PLXNA4 NR4A1

8.84e-08197506079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC ANO6 DNAH5 PCDH20 CNTN1

1.34e-0617050517bd7fd25a2657cb536ad47e294332920f759e95
ToppCellCTRL-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

DOCK1 SULF2 ENPP2 SCARB2 PLXNA4

1.50e-06174505ff4315e9fad198cc323fc987deb8652da137cf98
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FLNA SULF2 ENTPD1 TENM1 MMP13

1.98e-0618450539168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCellE16.5-samps-Mesenchymal-Myofibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZNF536 SULF2 ENPP2 ENTPD1 CACNA1G

2.08e-06186505e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCellCF-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

DOCK1 SULF2 ENPP2 SCARB2 PLXNA4

2.14e-06187505adc79e5804ab98006dbdf1d76ef0d8f85cc5cb0f
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA2D1 ZNF536 ENPP2 TRPS1 PLXNA4

2.14e-06187505c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellE15.5-Mesenchymal-myocytic_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA CACNA2D1 ZNF536 SULF2 ENTPD1

2.50e-061935053316d6a39abb6a518d45b846254325fc7a8b2035
ToppCellE15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA CACNA2D1 ZNF536 SULF2 ENTPD1

2.50e-06193505e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 ZNF536 ENPP2 ENTPD1 PCDH20

2.63e-06195505b0d408f8bc1701a87596ed55efcd90749fee33e6
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 ZNF536 ENPP2 ENTPD1 PCDH20

2.63e-06195505a486a7acea0e91048cc48afa0dbd3926d30bc217
ToppCellMatrixFB-Fibroblast-B_(Myofibroblast)|MatrixFB / shred on cell class and cell subclass (v4)

ZNF536 ENPP2 ENTPD1 PLXNA4 NR4A1

2.69e-0619650538ea0eaf42f95c321ca23570d0d7752980cf00f8
ToppCellP03-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZNF536 ENPP2 ENTPD1 PLXNA4 NR4A1

2.76e-061975052cec938caf6ffd031cea37277071487e59b2c71c
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA ZNF536 SULF2 ENPP2 ENTPD1

2.83e-0619850563f7d25201613bd3404c28fb936954190bca91d3
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FLNA ZNF536 ENTPD1 PLXNA4 NR4A1

2.83e-061985052d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA ZNF536 SULF2 ENPP2 ENTPD1

2.83e-06198505a73534b6ca202c277a70a52281d5b97a3e6cb8ef
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

DNAH12 PTPRC ENPP2 TRPV4 DNAH5

2.97e-06200505177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

DNAH12 PTPRC ENPP2 TRPV4 TRDN

2.97e-0620050513ec8afea86e4a10599c924871ba4e325b0a8013
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA SULF2 PTPRC ANO6

2.90e-05157504ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

VPS13A RXFP1 NR4A1 KMT2E

3.05e-0515950418e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRPV4 CACNA1G RXFP1 P3H4

3.20e-051615049703b7e67d9fadb6129cad166bd01be915042e44
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FLNA ZNF536 PLXNA4 NR4A1

3.36e-051635041e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA SULF2 TRPS1 NR4A1

3.52e-0516550411227bff52eed30b80937fdb1968d0b8e6d30365
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA SULF2 TRPS1 NR4A1

3.52e-05165504036f9749048e5e50769cc3210339bf4da469215d
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOD1 LRP12 ANO6 TRPV4

3.78e-051685044ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

SULF2 DNAH12 ENPP2 PLXNA4

3.78e-05168504dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A12 FLNA PTPRC NR4A1

3.78e-051685044b5be7c6662eceddf90a65015f12908278d1664e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF536 TENM1 RXFP1 PCDH20

3.78e-05168504f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A12 FLNA PTPRC NR4A1

3.78e-05168504689c41f6e9f65381570991cc311cba49a57ec955
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA ZNF536 ENPP2 TRDN

3.87e-0516950488aa2246ede582c2e11de63228d76f520889ecb3
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOD1 LRP12 ANO6 TRPV4

3.87e-05169504454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

ENPP2 ENTPD1 SKIDA1 MMP13

3.87e-05169504241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA ZNF536 ENPP2 TRDN

3.87e-05169504a6a5b00912b653fad2ca7f096deaf35c9ef85e5b
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA ZNF536 ENPP2 TRDN

3.87e-0516950442a9b8c77d2a4d68b01e4db38f8a1af53c9c814f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF536 ENPP2 RXFP1 PCDH20

4.05e-05171504f9ae7964a3740f559431125c17c660549798cccc
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC ANO6 TENM1 DNAH5

4.43e-05175504f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SULF2 RXFP2 TENM1 TRDN

4.63e-051775042b675840b7d2bb536c2c600936733bd9e97e7120
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA PLA2G4B TRPS1 TENM1

4.63e-05177504e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC ANO6 DNAH5 PCDH20

4.73e-0517850409a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNA ZNF536 PLXNA4 P3H4

5.05e-05181504d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

PTPRC UBR5 VPS13A LRBA

5.05e-05181504f2315414e714ac86211546a935660c4be6e85f1b
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

CACNA2D1 ZNF536 ENPP2 ENTPD1

5.27e-05183504de08f9ea02b7244d5a8788064631d10f06565337
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.27e-051835045472cdce6d99314d229418412acf1fff6340db7d
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

SULF2 PTPRC ENTPD1 TRPS1

5.27e-05183504c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 DNAH5 TRDN CNTN1

5.38e-051845042cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACOD1 LRP12 SULF2 SCARB2

5.38e-05184504fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.38e-051845045939527d24d299e562e707469c9123890edd76be
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.38e-05184504a2191dd5546efd357b23e625beb3c5820476f243
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 DNAH5 TRDN CNTN1

5.38e-05184504ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM1 DNAH5 TRDN CNTN1

5.38e-051845042b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.50e-051855041d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA LRP12 SULF2 PTPRC

5.50e-0518550453a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.50e-05185504b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.61e-0518650490eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.61e-05186504bd8a9753df219084e19e7f94447856e86608325c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.73e-05187504f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.73e-0518750497e520705491c8f52a32025311a9fa7b9176979a
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.73e-05187504b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.85e-0518850414072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

SULF2 ENPP2 RXFP1 NR4A1

5.85e-05188504eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FLNA ENTPD1 PLXNA4 TENM1

5.85e-0518850474f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.85e-05188504b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

CACNA2D1 ZNF536 ENPP2 PLXNA4

5.97e-0518950444e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK1 ZNF536 ENPP2 HAPLN2

5.97e-05189504b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FLNA ZNF536 ENTPD1 PLXNA4

5.97e-05189504da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SULF2 ENTPD1 TENM1

6.10e-05190504e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ENPP2 ENTPD1 RXFP1 NR4A1

6.10e-0519050407b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC2|Lung / Manually curated celltypes from each tissue

SULF2 ENPP2 ENTPD1 NR4A1

6.10e-05190504468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCellCOVID-19_Severe-pDC|COVID-19_Severe / disease group, cell group and cell class

SULF2 ENPP2 SCARB2 PLXNA4

6.10e-05190504c5ab6b7492fb86aff3d2af3eb671c9f985ae4aeb
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FLNA ZNF536 ENTPD1 PLXNA4

6.35e-051925047ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SULF2 ENTPD1 NR4A1

6.48e-051935044aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SULF2 PTPRC ENTPD1 TRPS1

6.48e-0519350458e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FLNA ZNF536 ENPP2 PLXNA4

6.48e-051935042f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SULF2 ENTPD1 NR4A1

6.48e-051935045578f7cb3ec68c9a38cc5304b618b81283024d5e
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

UBR5 SETD5 LRBA KMT2E

6.48e-05193504e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SULF2 ENPP2 ENTPD1 NR4A1

6.48e-05193504704378de39e1b6f108ab5b0ecbd594d414ec8ae4
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK1 ZNF536 ENPP2 HAPLN2

6.61e-05194504cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SULF2 ENPP2 ENTPD1 NR4A1

6.61e-0519450436f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCellP28-Mesenchymal-myocytic_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA ENPP2 NR4A1 TRDN

6.61e-0519450483e45441c74b7f50b6725876b583229280179dc2
ToppCellP28-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZNF536 ENPP2 NR4A1 TRDN

6.61e-051945043c661c6768c3f05d2aba03d329adb257ca201b2d
ToppCellControl-Myeloid-Migratory_DC|Control / Condition, Lineage and Cell class

SULF2 ENPP2 ENTPD1 NR4A1

6.61e-05194504374076e60dcee83eb1814aa6b55b77668909f40b
ToppCellCV-Moderate-0|CV / Virus stimulation, Condition and Cluster

PTPRC ENTPD1 NR4A1 KMT2E

6.61e-051945049ff69139dae007fcc349daefcb5021defb0e0d2a
ToppCellControl-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

SULF2 ENPP2 ENTPD1 NR4A1

6.74e-051955049f1ad04abc6a6c5e093ea24b60732871b1fad5a4
ToppCellE12.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA SULF2 ENTPD1 RXFP1

6.74e-05195504bff7685784688425bebd78b0f284a6d4475a9415
ToppCellE12.5-Mesenchymal-myocytic_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA SULF2 ENTPD1 RXFP1

6.74e-05195504aed243418cdb5df4563a7b935c1ecbd744590901
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA2D1 ZNF536 ENPP2 ENTPD1

6.74e-051955042414b158dc7bdec43a9671544bfb7ffc5f5168fd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SULF2 ENPP2 HAPLN2 CNTN1

6.88e-05196504f068ce40bf35021baf1468ae9ce30a92162eb14d
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

SULF2 PTPRC ENTPD1 TRPS1

6.88e-05196504cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNA ENTPD1 PLXNA4 HAPLN2

6.88e-051965049830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellP07-Mesenchymal-myocytic_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA ZNF536 ENTPD1 NR4A1

7.01e-05197504378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PTPRC VPS13A TENM1 LRBA

7.01e-0519750457ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK1 ZNF536 ENPP2 HAPLN2

7.01e-0519750482b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SULF2 ENPP2 ENTPD1 NR4A1

7.01e-05197504513ada82bbbb6a624d89edaa54f8c4a303dfb5e7
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ENPP2 TRPV4 MMP13 P3H4

7.01e-0519750463b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SULF2 ENPP2 ENTPD1 NR4A1

7.01e-051975046f83fc049f38f3de6bc5180ad4b51ceb4d5dcdb6
ToppCellP07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA ZNF536 ENTPD1 NR4A1

7.01e-05197504b1135378d768fbbe62a75747d1e8653d35252187
ToppCellControl-Myeloid-cDC|Control / Disease group,lineage and cell class （2021.01.30）

SULF2 ENPP2 ENTPD1 NR4A1

7.01e-05197504aef933107da42a763b35041c90950db07707c0cb
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SULF2 ENPP2 ENTPD1 NR4A1

7.01e-0519750415e683f4a610aad3e06723747c8e56ca25f57414
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA2D1 SULF2 PCDH20 CNTN1

7.01e-05197504b8dc192fc98428bbb701cc2ea57fc8ad93397785
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SULF2 ENPP2 ENTPD1 NR4A1

7.01e-051975046ac50c02899531a25885749d5305da788dfa9dbc
Drugtinyatoxin

CACNA2D1 TRPV4 TRPV3

3.57e-0614503CID000005481
DiseaseDisproportionate short stature

FLNA TRPS1 TRPV4 MMP13

8.31e-0677494C0878659
Diseasetetralogy of Fallot (implicated_via_orthology)

DOCK1 DNAH5

2.43e-0414492DOID:6419 (implicated_via_orthology)
DiseaseLiver Cirrhosis, Experimental

FLNA PTPRC TCF20 ANO6 ENPP2 SRI MMP13

2.74e-04774497C0023893
DiseaseSchwartz-Jampel Syndrome, Type 1

FLNA TRPV4

3.19e-0416492C4551479
DiseaseSpondyloepiphyseal Dysplasia

FLNA TRPV4

3.19e-0416492C0038015
DiseaseSchwartz-Jampel Syndrome

FLNA TRPV4

3.19e-0416492C0036391
DiseaseMelnick-Needles Syndrome

FLNA TRPV4

3.19e-0416492C0025237
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

FLNA TRPV4

3.19e-0416492C3541456
DiseaseVan Buchem disease

FLNA TRPV4

3.62e-0417492C0432272
DiseaseTourette syndrome, schizophrenia

ZNF536 TCF20

4.06e-0418492EFO_0004895, MONDO_0005090
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA TRPS1

4.54e-0419492DOID:2256 (is_implicated_in)
DiseaseDyschondroplasias

FLNA TRPV4

4.54e-0419492C0013366
DiseaseOsteochondrodysplasias

FLNA TRPV4

4.54e-0419492C0029422
DiseaseMultiple Epiphyseal Dysplasia

FLNA TRPV4

5.04e-0420492C0026760
Diseaselipoprotein measurement

DOCK1 SULF2 TRPS1

7.16e-04105493EFO_0004732
DiseaseIntellectual Disability

TCF20 ENTPD1 CACNA1G FUCA1 KMT2E

8.60e-04447495C3714756
Diseasenecrotizing enterocolitis

TCF20 TRPS1

9.23e-0427492EFO_0003928
DiseaseL-Selectin measurement

SULF2 TENM1

1.22e-0331492EFO_0008202
Diseaseasymmetrical dimethylarginine measurement, serum dimethylarginine measurement

CACNA2D1 ZNF536

1.38e-0333492EFO_0005418, EFO_0006522
Diseaseblood barium measurement

CACNA2D1 SULF2

1.46e-0334492EFO_0021528

Protein segments in the cluster

PeptideGeneStartEntry
ALGGKPNNAYYFIGF

ATG4A

256

Q8WYN0
FPGAFGVYEYPFEPA

ASCL5

141

Q7RTU5
FLPGTGYPKGYFVQN

GUSBP11

216

Q6P575
GYPKGYFVQNTDFDF

GUSBP11

221

Q6P575
FKFEDFQVYGCYPGP

NR4A1

101

P22736
FFKGKFVGYPGDPVY

ANO6

571

Q4KMQ2
NKDFSFFVPENFPGY

PCDH20

641

Q8N6Y1
PGPDGFTAEFYQRYK

nan

471

O00370
FYGTFNSPNYPDFYP

LRP12

266

Q9Y561
SFGFPRPQQAAYGTY

HAPLN2

321

Q9GZV7
FTYYPNPVFEAFGPS

PLXNA4

1136

Q9HCM2
EKNGYIYFFNGPIQF

MMP13

436

P45452
NYPPGFSYADFGPQF

FUCA1

96

P04066
KGFFNIYHPFDPVAY

DDHD2

531

O94830
ENPHYKFSPSGNYFA

DNAH12

2736

Q6ZR08
EQFEANGYFFKRPYP

KMT2E

366

Q8IZD2
YGPDAFFNFPGKSAA

LRBA

201

P50851
EFSPYEVGFPKYGAF

PLA2G4B

456

P0C869
PPLQGDFGAFSAFYF

ENTPD1

351

P49961
PDYFAVGYYGQGFPT

DOCK1

1336

Q14185
VYGPFGYIKNPYNIF

CACNA1G

796

O43497
DNYVFTAPYFNKSGP

CACNA2D1

771

P54289
GTFDIFYTAPQPGKY

FLNA

1706

P21333
YGNNFGYIVAFKPFD

CNTN1

736

Q12860
GFGAFYANYSPKVLP

ACOD1

241

A6NK06
FPGYPIYGTNFHGTF

KRTAP7-1

11

Q8IUC3
FYSEQPDFSGHKYGP

ENPP2

306

Q13822
MFGPDFSFYQGYNIP

DNAH5

4276

Q8TE73
NYIGQFLPGYEAPAF

HPD

151

P32754
GAFYPNYFTFGQPDE

TDRD9

746

Q8NDG6
RFPYLCYKNGGGAFF

SLC6A12

61

P48065
QGNYVAFPSDPAYFR

SKIDA1

201

Q1XH10
PYPFVLFYSKFNGVE

SETD5

321

Q9C0A6
DYFGNFYGKNGVCFP

RXFP2

561

Q8WXD0
SPYFGLFYEKNGTND

SCARB2

196

Q14108
KPFNLYSFENNYPVG

TENM1

2401

Q9UKZ4
FNYESPSKGGNFPSF

TRPS1

86

Q9UHF7
EAFFYEPYQGAIQGP

VPS13A

2881

Q96RL7
FGPPNTYYEGGYFKA

CDC34

46

P49427
LGYYFGFRKQPYDNP

TM9SF4

466

Q92544
AGAQYEKYSFRGFPP

P3H4

16

Q92791
EFFKNYYGTNGVCFP

RXFP1

551

Q9HBX9
NMGDLFGPFYPQDYA

TCF20

1716

Q9UGU0
NFKAPFYPIQYLGDF

SLF1

181

Q9BQI6
NFPSDFYKQFGVYPG

ZNF536

1106

O15090
GYNGYGFQFPFTPAD

TRDN

696

Q13061
NPKYQHEGFYFGETP

TRPV3

251

Q8NET8
TFKAYFHNGDYPGEP

PTPRC

551

P08575
RFFQPKDEGGYFYFG

TRPV4

271

Q9HBA0
AFPGQTQDPLYGYFA

SRI

26

P30626
FGKYLNEYNGSYVPP

SULF2

141

Q8IWU5
NAPLFYQPGKRGFYT

UBR5

2501

O95071