Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO5A DYNC2H1 DNAH14 MYH14 KIF5B MYO18B KIF13A

5.04e-051181627GO:0003774
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC5 ABCC10

6.03e-05101623GO:0043225
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCC5 ABCC10

2.22e-04151623GO:0008559
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

LCA5 IFT140 MYO5A DYNC2H1 CCDC186 STK11 AP3B2 WDR35 KIF5B KIF13A

1.19e-0522516210GO:0030705
GeneOntologyBiologicalProcessvesicle cytoskeletal trafficking

MYO5A CCDC186 STK11 AP3B2 KIF5B KIF13A

1.44e-05671626GO:0099518
GeneOntologyBiologicalProcesstransport along microtubule

LCA5 IFT140 MYO5A DYNC2H1 STK11 AP3B2 WDR35 KIF5B KIF13A

2.65e-051971629GO:0010970
GeneOntologyBiologicalProcessprotein localization to cilium

IFT140 DYNC2H1 FSIP2 WDR35 CROCC CCDC40

3.20e-05771626GO:0061512
GeneOntologyBiologicalProcessmicrotubule-based transport

LCA5 IFT140 MYO5A DYNC2H1 STK11 AP3B2 WDR35 KIF5B KIF13A CCDC40

3.26e-0525316210GO:0099111
GeneOntologyBiologicalProcessmicrotubule-based process

LCA5 IFT140 MAP7D3 GIT1 MYO5A CLIP2 DYNC2H1 HAUS5 DNAH14 FSIP2 STK11 EHHADH CEP250 AP3B2 CCDC78 WDR35 UHRF1 KIF5B CROCC KIF13A CCDC40

8.62e-05105816221GO:0007017
DomainARM-type_fold

NOC2L PKP4 XPO4 ITPR1 UPF2 PIK3C2B AP3B2 UTP20 PDS5A DAAM2 CTNND2 HECTD1 UNC79 SYMPK

1.58e-0633916214IPR016024
DomainSPIN-2

SPIN2A SPIN2B

7.48e-0521622IPR029564
Domain-

PKP4 XPO4 AP3B2 UTP20 PDS5A DAAM2 CTNND2 HECTD1 SYMPK

1.41e-0422216291.25.10.10
DomainUbiquitin-rel_dom

UBXN6 PTPN13 PIK3C2B RASSF1 UBAC1 UHRF1 FRMPD3 TP53BP2

2.07e-041841628IPR029071
Domain-

SLF1 GIT1 LRRK1 TRANK1 ASB6 ASB7 ANKIB1 HECTD1 TP53BP2

3.22e-0424816291.25.40.20
DomainANK

SLF1 GIT1 LRRK1 TRANK1 ASB6 ASB7 ANKIB1 HECTD1 TP53BP2

3.52e-042511629SM00248
DomainANK_REPEAT

SLF1 GIT1 LRRK1 TRANK1 ASB6 ASB7 ANKIB1 HECTD1 TP53BP2

3.72e-042531629PS50088
DomainIQ

MYO5A OBSCN PPEF2 MYH14 MYO18B

3.79e-04711625PF00612
DomainAnkyrin_rpt-contain_dom

SLF1 GIT1 LRRK1 TRANK1 ASB6 ASB7 ANKIB1 HECTD1 TP53BP2

3.83e-042541629IPR020683
DomainANK_REP_REGION

SLF1 GIT1 LRRK1 TRANK1 ASB6 ASB7 ANKIB1 HECTD1 TP53BP2

3.83e-042541629PS50297
DomainMib_Herc2

HERC2 HECTD1

4.44e-0441622IPR010606
DomainMIB_HERC2

HERC2 HECTD1

4.44e-0441622PS51416
DomainMIB_HERC2

HERC2 HECTD1

4.44e-0441622PF06701
DomainAnkyrin_rpt

SLF1 GIT1 LRRK1 TRANK1 ASB6 ASB7 ANKIB1 HECTD1 TP53BP2

4.80e-042621629IPR002110
DomainARM-like

PKP4 XPO4 AP3B2 UTP20 PDS5A DAAM2 CTNND2 HECTD1 SYMPK

5.96e-042701629IPR011989
DomainIQ

MYO5A OBSCN PPEF2 MYH14 MYO18B

6.95e-04811625SM00015
DomainATP-guanido_PTrfase

CENPF CKB

7.35e-0451622IPR000749
DomainSPIN/Ssty

SPIN2A SPIN2B

7.35e-0451622IPR003671
DomainSpin-Ssty

SPIN2A SPIN2B

7.35e-0451622PF02513
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CAD EIF4H MYO5A NOC2L MARS1 PKP4 TUT7 PHB2 KRR1 PRPF8 POLR3A SMTN RAD50 PDE12 UPF2 MYH14 PLEKHG3 SGPL1 MRPS15 SMARCA1 ANKIB1 UTP20 PDS5A KIF5B HERC2 GOLGA4 TP53BP2

2.37e-1013531642729467282
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GPD2 DENND2A CAD GIT1 MYO5A CLIP2 MARS1 PKP4 PHB2 FAM98B SHROOM2 CKB DIP2A UPF2 MYH14 SRGAP3 SGPL1 AP3B2 PACS2 RIMBP2 CTNNA1 KIF5B CTNND2 CROCC PSPC1 TP53BP2

3.75e-0914311642637142655
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CAD GIT1 MYO5A CLIP2 CENPF PKP4 PHB2 EPM2AIP1 RAD50 NRXN1 SRGAP3 RIMBP2 CTNNA1 KIF5B QSER1 FRMPD3 HERC2 CTNND2 UNC79 GOLGA4 TP53BP2

6.23e-099631642128671696
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

EIF4H P3H3 CCDC186 PHB2 XPO4 CKB EIF2B1 CEP250 UTP20 KIF5B HECTD1 ATP2A3

1.26e-082851641232838362
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CAD MYO5A CENPF NOC2L TUT7 KRR1 PRPF8 RAD50 CKB MYH14 UTP20 PDS5A CTNNA1 KIF5B HERC2 HECTD1 SYMPK

1.51e-086531641722586326
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

GPD2 CAD CENPF DYNC2H1 NOC2L MARS1 PHB2 KRR1 PRPF8 POLR3A RAD50 CKB PDE12 MYH14 EIF2B1 SMARCA1 UHRF1 UTP20 PDS5A PNPLA8 KIF5B MYO18B PSPC1 GOLGA4

6.64e-0814251642430948266
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

GPD2 CAD EIF4H MYO5A CENPF NOC2L MARS1 HAUS5 PRPF8 RAD50 CKB SMPDL3B MYH14 PLEKHG3 UHRF1 UTP20 CTNNA1 KIF5B HERC2 PSPC1

8.88e-0810241642024711643
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

KRT13 EIF4H CENPF PRPF8 RAD50 CKB PDE12 SRGAP3 SGPL1 AP3B2 PNPLA8 CTNNA1 KIF5B PSPC1

1.18e-074981641436634849
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

KRT13 CAD MAP7D3 MYO5A CENPF NOC2L MARS1 PKP4 TUT7 PHB2 KRR1 PRPF8 RAD50 UPF2 PLEKHG3 SGPL1 SMARCA1 UTP20 CTNNA1 KIF5B PSPC1

5.43e-0712571642136526897
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

CAD MAP7D3 MYO5A MARS1 PHB2 PRPF8 DENND2B ITPR1 SMTN GNG12 MYH14 PLEKHG3 EIF2B1 MRPS15 UHRF1 UTP20 CTNNA1 KIF5B

6.25e-079491641836574265
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SH3TC2 CLIP2 DYNC2H1 CCDC85A SAMD9L SCAP LMBR1L PLEKHG3 SGPL1 WDR35 PDS5A ZNF518B HECTD1

7.00e-074931641315368895
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CENPF MARS1 OBSCN AK9 NEB PRPF8 CBR3 MAP3K4 DIP2A TRANK1 PIK3C2B CTNNA1 ATP2A3

7.66e-074971641336774506
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

CAD CENPF PHB2 PRPF8 MAP3K4 POLR3A RAD50 PDE12 UPF2 MRPS15 SMARCA1 UTP20 PDS5A KIF5B ATP2A3

1.38e-067041641529955894
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SLC37A1 COL26A1 MYO5A MARS1 OBSCN SHROOM2 DENND2B DNAH14 PCNX2 PTPN13 SMPDL3B FAM13A GNG12 MYH14 PLEKHG3 RALGPS1 ANKIB1 KCNN2 QSER1 CROCC HECTD1 GOLGA4

2.17e-0614891642228611215
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MCHR1 GIT1 MYO5A CLIP2 ABCC5 ZNF227 REV3L PRPF8 SHROOM2 CBR3 CCDC85A DIP2A PTPN13 MYH14 DAAM2 CTNNA1 HERC2 CTNND2 LNX1 HECTD1

3.03e-0612851642035914814
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

LCA5 MAP7D3 EIF4H GIT1 NOC2L BACH2 PKP4 TUT7 HAUS5 ATG2A RAD50 CKB CEP250 KIF5B HERC2 TP53BP2

3.14e-068531641628718761
Pubmed

DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.

PKP4 CCDC85A CTNND2

3.55e-067164325009281
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

LCA5 IFT140 MAP7D3 GIT1 DYNC2H1 PHB2 XPO4 TBC1D25 PRPF8 RAD50 RNF214 PTPN13 NRXN1 EIF2B1 CCDC154 WDR35 CTNNA1 QSER1 TP53BP2 CCDC40

4.57e-0613211642027173435
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

GPD2 CAD NOC2L MARS1 PHB2 XPO4 FAM98B KRR1 PRPF8 POLR3A ITPR1 SMTN RAD50 CKB GNG12 PLEKHG3 SGPL1 EIF2B1 MRPS15 PDS5A CTNNA1

4.61e-0614401642130833792
Pubmed

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

ABCC3 ABCC5 ABCC10

5.67e-068164315802388
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

CAD MYO5A TUT7 PRPF8 MYH14 UTP20 HERC2 HECTD1

5.67e-06202164833005030
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

IFT140 GIT1 MARS1 CCDC186 PKP4 HAUS5 UBXN6 ZNF227 CCDC85A CKB DUS2 RASSF1 PDS5A ALAS1 CTNNA1 KIF5B CTNND2 TP53BP2

6.65e-0611241641821900206
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

DAGLB DYNC2H1 NOC2L MARS1 TUT7 PHB2 NCSTN PDE12 SCAP LMBR1L UTP20 PDS5A CTNNA1 KIF5B HECTD1 SYMPK

1.08e-059421641631073040
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

EIF4H HAUS5 PHB2 FAM98B PRPF8 POLR3A RAD50 CKB UPF2 MYH14 CEP250 AP3B2 MRPS15 KIF5B PSPC1

1.27e-058471641535235311
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

EIF4H MYO5A CENPF TUT7 XPO4 RAD50 PTPN13 MYH14 EIF2B1 CEP250 MRPS15 UTP20 HERC2 HECTD1

1.49e-057541641433060197
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

KRT13 CAD LDHAL6A MYO5A OBSCN PHB2 SMTN CKB PTPN13 SGPL1 WDR35 GOLGA4

1.65e-055641641221565611
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 OBSCN TBC1D25 LRRK1 ATG2A REV3L CTDSP2 PCNX2 DIP2A SCAP PIK3C2B RALGPS1 HERC2 HECTD1 ATP2A3 ABCC10 SYMPK

2.03e-0511051641735748872
Pubmed

A human MAP kinase interactome.

IFT140 KRT13 CLIP2 CCDC186 NEB MAP3K4 CEP250 BICRAL CTNNA1 KIF5B HERC2

2.14e-054861641120936779
Pubmed

Re: Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

ABCC3 ABCC5

2.21e-052164210340910
Pubmed

Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells.

CEP250 CROCC

2.21e-052164216339073
Pubmed

C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.

CEP250 CROCC

2.21e-052164223070519
Pubmed

The arm-repeat protein NPRAP (neurojungin) is a constituent of the plaques of the outer limiting zone in the retina, defining a novel type of adhering junction.

CTNND2 SYMPK

2.21e-052164210413599
Pubmed

Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression.

SPIN2A SPIN2B

2.21e-052164212145692
Pubmed

Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma.

ABCC3 ABCC5

2.21e-052164215688370
Pubmed

Blended phenotype of combination of HERC2 and AP3B2 deficiency and Angelman syndrome caused by paternal isodisomy of chromosome 15.

AP3B2 HERC2

2.21e-052164234042275
Pubmed

Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family.

PKP4 CTNND2

2.21e-05216429342840
Pubmed

Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

ABCC3 ABCC5

2.21e-05216429827529
Pubmed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.

MYO5A LRRK1 ITPR1 AP3B2 KCNN2

2.38e-0572164525917818
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

GIT1 MYO5A CLIP2 PKP4 UBXN6 R3HCC1 TBC1D25 DNAH14 CTDSP2 SMTN DIP2A UHRF1 KIF13A ABCC10 FILIP1L

3.52e-059251641528986522
Pubmed

Defining the membrane proteome of NK cells.

SLC37A1 CAD MAP7D3 EIF4H GIT1 MYO5A MARS1 ACOX1 NCSTN KRR1 PRPF8 POLR3A ITPR1 RAD50 MYH14 KIF5B HERC2

4.06e-0511681641719946888
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

GIT1 CLIP2 PHB2 PTPN13 SRGAP3 SGPL1 CEP250 AP3B2 PNPLA8 HERC2

4.07e-054301641032581705
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

GPD2 KRT13 CAD GIT1 MARS1 POLR2J PHB2 FAM98B KRR1 PRPF8 RAD50 CKB PDS5A CTNNA1 KIF5B TRIM47 PSPC1 HECTD1 GOLGA4

4.19e-0514151641928515276
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CAD GIT1 NOC2L TUT7 POLR2J MAP3K4 ITPR1 MYH14 HERC2 HECTD1

4.93e-054401641034244565
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CENPF OBSCN REV3L PRPF8 DNAH14 DIP2A SAMD9L PDE12 SRGAP3 UBAC1 UTP20 PDS5A SYMPK

5.05e-057361641329676528
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

MAP7D3 EIF4H GIT1 HAUS5 PHB2 RAD50 CDAN1 GNG12 MYH14 UHRF1 KIF5B TP53BP2

6.06e-056451641225281560
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAP7D3 GIT1 DENND2B FSIP2 PTPN13 FAM13A PIK3C2B PLEKHG3 KIF5B KIF13A HECTD1 MUSK GOLGA4 TP53BP2

6.28e-058611641436931259
Pubmed

Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas.

CDX2 STK11

6.61e-053164214760387
Pubmed

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

ABCC3 ABCC5

6.61e-05316429270026
Pubmed

The serologically defined colon cancer antigen-3 interacts with the protein tyrosine phosphatase PTPN13 and is involved in the regulation of cytokinesis.

GIT1 PTPN13

6.61e-053164223108400
Pubmed

ATP-binding cassette C transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells.

ABCC3 ABCC5

6.61e-053164219077464
Pubmed

KRT13, FAIM2 and CYP2W1 mRNA expression in oral squamous cell carcinoma patients with risk habits.

KRT13 CYP2W1

6.61e-053164225735388
Pubmed

PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.

PKP4 CTNND2

6.61e-053164210896674
Pubmed

The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly.

CEP250 TP53BP2

6.61e-053164225660448
Pubmed

Specific variants in WDR35 cause a distinctive form of Ellis-van Creveld syndrome by disrupting the recruitment of the EvC complex and SMO into the cilium.

DYNC2H1 WDR35

6.61e-053164225908617
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MAP7D3 MYO5A CENPF NOC2L TUT7 KRR1 PRPF8 UPF2 EIF2B1 UHRF1 UTP20 HERC2 HECTD1

6.89e-057591641335915203
Pubmed

Comprehensive Proteomic Analysis of PGC7-Interacting Proteins.

KRT13 MARS1 NCSTN KRR1 RNF214 MRPS15 UHRF1 CTNNA1

7.01e-05287164828712289
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

DYNC2H1 ATG2A KRR1 PRPF8 CBR3 POLR3A RAD50 CKB STK11 PDE12 RIMBP2 KIF5B MPND HERC2 HECTD1

8.91e-0510051641519615732
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DYNC2H1 UBXN6 NCSTN NEB SHROOM2 CKB STK11 PTPN13 SMPDL3B GNG12 MYH14 CEP250 UBAC1 CROCC CCDC180

1.00e-0410161641519056867
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

GIT1 NOC2L MARS1 PHB2 XPO4 LRRK1 FAM98B PRPF8 RAD50 CDAN1 EIF2B1 UBAC1 PDS5A KIF5B HERC2 ATP2A3 UNC79

1.28e-0412841641717353931
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

CAD EIF4H PKP4 POLR2J PHB2 REV3L PRPF8 CKB STK11 PTPN13 WDR35 HERC2 PSPC1 SYMPK

1.29e-049221641427609421
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

CAD MYO5A NEB PRPF8 RAD50 CEP250 KIF13A

1.30e-04234164736243803
Pubmed

Sterol carrier protein-2.

ACOX1 EHHADH

1.32e-044164210856712
Pubmed

Recurrent CNVs disrupt three candidate genes in schizophrenia patients.

NRXN1 CTNND2

1.32e-044164218940311
Pubmed

Divergent human and mouse orthologs of a novel gene (WBSCR15/Wbscr15) reside within the genomic interval commonly deleted in Williams syndrome.

EIF4H CLIP2

1.32e-044164211124535
Pubmed

Myosin5a tail associates directly with Rab3A-containing compartments in neurons.

MYO5A KIF5B

1.32e-044164221349835
Pubmed

Kisspeptin excites gonadotropin-releasing hormone neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels.

ITPR1 KISS1R

1.32e-044164218483150
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

DYNC2H1 OBSCN

1.32e-044164226147384
Pubmed

Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells.

ABCC3 ABCC5

1.32e-044164219956884
Pubmed

PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

PKP4 CTNND2

1.32e-044164219706687
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRANK1 RALGPS1 DAAM2 RIMBP2 HERC2

1.38e-0410416459205841
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

CAD GIT1 FAM98B PRPF8 RAD50 RNF214 MYH14 SGPL1 SMARCA1 UHRF1 PSPC1

1.42e-046011641133658012
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

GPD2 CAD MYO5A PKP4 XPO4 PPEF2 CTDSP2 ITPR1 VIPAS39 PTPN13 CTNNA1 HERC2 GOLGA4 TP53BP2 SYMPK

1.42e-0410491641527880917
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC3 ABCC5 ABCC10

1.48e-042216438894702
Pubmed

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.

CLIP2 NOC2L PHB2 NCSTN RAD50 CKB PTPN13 SMPDL3B GNG12 CTNNA1 PSPC1

1.49e-046041641137616343
Pubmed

Human transcription factor protein interaction networks.

CAD SLF1 MYO5A MARS1 PHB2 KRR1 RAD50 CKB RNF214 GNG12 MYH14 MRPS15 SMARCA1 PDS5A QSER1 HERC2 FILIP1L SYMPK

1.50e-0414291641835140242
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

GPD2 ATG2A CTDSP2 ITPR1 SLC7A2 VIPAS39 PTPN13 SCAP SGPL1 GOLGA4

1.50e-045041641034432599
Pubmed

Elevation of hsa-miR-7-5p level mediated by CtBP1-p300-AP1 complex targets ATXN1 to trigger NF-κB-dependent inflammation response.

GPD2 PHB2 DIP2A SGPL1 UHRF1 PSPC1

1.68e-04171164636629882
Pubmed

p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.

PKP4 CTNNA1 CTNND2

1.70e-0423164325523391
Pubmed

A proteome-scale map of the SARS-CoV-2-human contactome.

KRT13 MARS1 THAP9 EHHADH CEP250 DAAM2

1.79e-04173164636217029
Pubmed

Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.

PKP4 BPIFA1 CTNND2 LNX1

1.89e-0460164422889411
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC3 P3H3 TUT7 NCSTN ITGA7 ITPR1 SCAP SGPL1 UHRF1 UTP20 CTNNA1 KIF5B HECTD1 ATP2A3 FKBP2 SYMPK

1.90e-0412011641635696571
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

CENPF RAD50 MYH14 SMARCA1 CDT1 HERC2 ABCC10

1.95e-04250164733536335
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MARS1 TUT7 OBSCN NCSTN KRR1 SHROOM2 ITPR1 SMTN STK11 PTPN13 SCAP SGPL1 RASSF1 QSER1 KIF13A

2.03e-0410841641511544199
Pubmed

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin.

PKP4 CTNND2

2.19e-045164210037471
Pubmed

Chromosomal mapping of human armadillo genes belonging to the p120(ctn)/plakophilin subfamily.

PKP4 CTNND2

2.19e-04516429721216
Pubmed

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.

TUT7 UPF2

2.19e-045164230617251
Pubmed

CCDC102B functions in centrosome linker assembly and centrosome cohesion.

CEP250 CROCC

2.19e-045164230404835
Pubmed

The kinase domains of obscurin interact with intercellular adhesion proteins.

OBSCN KCNN2

2.19e-045164223392350
Pubmed

Efflux protein expression in human stem cell-derived retinal pigment epithelial cells.

ABCC3 ABCC5

2.19e-045164222272278
Pubmed

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.

CEP250 CROCC

2.19e-045164224554434
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

CAD GIT1 SHROOM2 CEP250 KIF5B HECTD1 TP53BP2

2.20e-04255164715324660
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DENND2A IFT140 HAUS5 XPO4 LRRK1 NCSTN ATG2A TRANK1 RALGPS1 ANKIB1

2.21e-045291641014621295
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

KRT13 CAD EIF4H MYO5A DYNC2H1 NOC2L PKP4 PHB2 PRPF8 ITPR1 DIP2A PTPN13 PDE12 PNPLA8 ALAS1 CTNNA1 HERC2 GOLGA4

2.44e-0414871641833957083
Pubmed

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

KRT13 CAD PHB2 FAM98B EIF2B1 MRPS15 KIF5B PSPC1

2.52e-04346164825324306
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

GIT1 MYO5A CLIP2 PKP4 SRGAP3 RIMBP2 CTNNA1 CTNND2

2.57e-04347164817114649
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

GPD2 CAD MAP7D3 CENPF TUT7 PHB2 POLR3A ITPR1 CKB DIP2A VIPAS39 PDE12 UPF2 MRPS15 PNPLA8 ALAS1 HERC2 PSPC1

2.62e-0414961641832877691
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

MYO5A UBXN6 PHB2 PRPF8 CKB MYH14 CTNNA1

2.71e-04264164732814769
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CLIP2 TUT7 PHB2 FAM98B KRR1 PRPF8 CKB DUS2 UPF2 MYH14 EHHADH EIF2B1 SMARCA1 UHRF1 KIF5B HERC2 PSPC1

2.77e-0413711641736244648
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

DAGLB EMILIN2 CTDSP2 FSIP2 SCAP ASB6 ALAS1 HERC2 SYMPK

3.04e-04450164916751776
Pubmed

Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo.

CDX2 STK11 CTNNA1

3.09e-0428164325588837
InteractionGSK3B interactions

GPD2 CDX2 CAD MAP7D3 EIF4H MARS1 HAUS5 UBXN6 ZNF227 MAP3K4 STK11 PTPN13 GNG12 LMBR1L RASSF1 UHRF1 CTNNA1 KIF5B HERC2 CTNND2 HECTD1 TP53BP2

1.65e-0686816122int:GSK3B
InteractionTMOD4 interactions

GIT1 MYO5A HAUS5 NEB ALAS1

3.11e-06291615int:TMOD4
InteractionKCTD13 interactions

GPD2 DENND2A CAD GIT1 MYO5A CLIP2 MARS1 PKP4 PHB2 FAM98B SHROOM2 CKB DIP2A UPF2 MYH14 SRGAP3 SGPL1 AP3B2 PACS2 RIMBP2 CTNNA1 KIF5B CTNND2 CROCC LNX1 PSPC1 TP53BP2

1.57e-05139416127int:KCTD13
InteractionYWHAZ interactions

LCA5 CAD MAP7D3 GIT1 MYO5A CLIP2 KRR1 NEB PRPF8 DENND2B THAP9 MAP3K4 ITPR1 FSIP2 PTPN13 FAM13A NRXN1 PIK3C2B SRGAP3 PLEKHG3 PACS2 KIF5B HERC2 LNX1 HECTD1 TP53BP2

1.70e-05131916126int:YWHAZ
InteractionHOOK1 interactions

GIT1 NOC2L HAUS5 UBXN6 ATG2A RAD50 LMBR1L MYH14 KIF5B HERC2

2.40e-0524016110int:HOOK1
CytobandXp11.1

SPIN2A SPIN2B

7.57e-0541642Xp11.1
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC5 ABCC10

4.12e-0513973807
GeneFamilyAnkyrin repeat domain containing

SLF1 GIT1 TRANK1 ASB6 ASB7 ANKIB1 HECTD1 TP53BP2

4.76e-05242978403
GeneFamilyTudor domain containing|Spindlin family

SPIN2A SPIN2B

2.82e-0459721089
GeneFamilyEMI domain containing

COL26A1 EMILIN2

5.88e-047972540
GeneFamilyTudor domain containing

SPIN2A UHRF1 SPIN2B

1.02e-0337973780
GeneFamilyPDZ domain containing

SHROOM2 PREX2 PTPN13 FRMPD3 LNX1

1.36e-031529751220
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

NOC2L PREX2 ITPR1 RIMBP2 TP53BP2

2.92e-03181975694
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

SLC37A1 CELF6 MYO5A PILRB CCDC186 BACH2 ABCC5 REV3L NEB SHROOM2 CCDC85A FSIP2 NRXN1 SRGAP3 RALGPS1 AP3B2 ANKIB1 RIMBP2 FRMPD3 CTNND2 KIF13A UNC79

1.67e-06110616422M39071
CoexpressionTCGA_GLIOBLASTOMA_COPY_NUMBER_UP

CTDSP2 SAMD9L PIK3C2B WDR35 ANKIB1 QSER1

7.72e-06751646M5536
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD2 DYNC2H1 REV3L CKB SLC7A2 NRXN1 KIF5B ATP2A3 GOLGA4

4.76e-0819516493e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD2 DYNC2H1 REV3L CKB SLC7A2 NRXN1 KIF5B ATP2A3 GOLGA4

4.76e-0819516497796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

LCA5 SLF1 DYNC2H1 AK9 CKB CCDC78 CCDC180 CCDC40

5.01e-0718816488f30535a32968a81a304315a49c0d90a77d36948
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC186 BTBD3 SAMD9L ANKIB1 PDS5A KIF5B GOLGA4 FILIP1L

5.65e-07191164809db184cb90fe282a14474d7217068c58092c6f8
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC85A AXDND1 ASB7 RALGPS1 UHRF1 PDS5A CDT1

3.68e-06173164712f779b8dce79431b2d1002ba524dd3f9566aeb0
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELF6 DENND2A ITGA7 PREX2 NRXN1 PROX2 DAAM2

5.53e-0618416474cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELF6 DENND2A ITGA7 PREX2 NRXN1 PROX2 DAAM2

5.53e-06184164739bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PKP4 ITPR1 CKB RALGPS1 RIMBP2 LNX1

6.15e-0618716477ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

LCA5 DENND2A IFT140 CCDC85A CKB DAAM2 SPIN2B

6.36e-061881647c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

LCA5 DENND2A IFT140 CCDC85A CKB DAAM2 SPIN2B

6.36e-0618816479155b9a92496e75646778c025b02947e9e9ec73a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PKP4 ITPR1 CKB RALGPS1 RIMBP2 LNX1

6.82e-0619016473dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC186 BTBD3 SAMD9L ANKIB1 PDS5A KIF5B FILIP1L

7.06e-06191164760c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC186 BTBD3 SAMD9L ANKIB1 PDS5A KIF5B FILIP1L

7.06e-061911647973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PKP4 ITPR1 CKB RALGPS1 RIMBP2 LNX1

7.30e-061921647562df5e87038c500dd3a003fe5374cb31946b145
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL26A1 CCDC186 TUT7 CCDC85A PREX2 SAMD9L HECTD1

7.81e-061941647e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 ACOX1 ABCC5 CKB SAMD9L FAM13A MYH14

8.92e-061981647efdbac7a3a02bff4ca48841772e0c136556c2b9b
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DENND2B SLC7A2 PTPN13 MYH14 SRGAP3 CTNNA1 HECTD1

9.53e-06200164797f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPD2 DENND2A P3H3 ITGA7 BTBD3 PTPN13 LMBR1L

9.53e-062001647f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

NEB FSIP2 EHHADH CCDC78 SPIN2A WDR35

2.06e-0515116462470162f4b56bc505db166a6eb0fa54847759df8
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBR3 POLR3A SAMD9L SMPDL3B MYO18B FILIP1L

2.14e-05152164682a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

GPD2 TRANK1 MYH14 SRGAP3 PACS2 BICRAL

2.48e-05156164625b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SLF1 TUT7 RAD50 TRANK1 BICRAL LRRC75A

3.63e-051671646948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellP15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAD AXDND1 PIK3C2B MYH14 DAAM2 BICRAL

3.63e-0516716465c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO5A POLR2J SRGAP3 UHRF1 CTNND2 UNC79

3.75e-051681646cc0dd43d5cda01e643d8e8d74ec7617d61890760
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ITGA7 BTBD3 PLEKHG3 CCDC78 DAAM2

4.42e-051731646d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A ITGA7 BTBD3 PLEKHG3 CCDC78 DAAM2

4.42e-0517316463c852ffe22f4a5b632463086b08c669310684e80
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 CDX2 PLCXD2 CYP2W1 SMPDL3B CDT1

4.42e-05173164681c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD CYP2W1 RALGPS1 UHRF1 CDT1 CCDC40

4.71e-051751646db6be3e9e339918418fcaf9001ea15207aa6c993
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD CYP2W1 RALGPS1 UHRF1 CDT1 CCDC40

4.71e-0517516468acac10c9eedccebcf3a3fe31bfee35afa54579f
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA7 CKB CDAN1 PLEKHG3 UHRF1 FILIP1L

5.02e-0517716464553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MCHR1 COL26A1 ITGA7 PLEKHG3 DAAM2 FILIP1L

5.18e-051781646066dbc4cc2083c549d98122ed44707127f34d582
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

IFT140 SHROOM2 DENND2B CCDC85A KCNN2 LNX1

5.51e-051801646b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCelldroplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP7D3 ACOX1 ABCC5 SLC7A2 SGPL1 PNPLA8

5.68e-0518116468fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 DENND2A ITGA7 NRXN1 PROX2 DAAM2

5.86e-0518216469edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 DENND2A ITGA7 NRXN1 PROX2 DAAM2

5.86e-051821646aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP7D3 ACOX1 ABCC5 SLC7A2 SGPL1 PNPLA8

5.86e-051821646be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 BTBD3 NRXN1 PLEKHG3 DAAM2 RIMBP2

6.04e-0518316460f02136359787bd78146617990968baa47a65d86
ToppCellfacs-Heart-RA-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 BTBD3 NRXN1 PLEKHG3 DAAM2 RIMBP2

6.04e-0518316462f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

DENND2A ITGA7 DENND2B PREX2 SLC7A2 DAAM2

6.41e-0518516464905adaeeffd353e089578e5ea614437dbe794e6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LCA5 COL26A1 LRRK1 CCDC85A FAM13A LNX1

6.61e-051861646bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LCA5 COL26A1 LRRK1 ITPR1 FAM13A LNX1

6.80e-051871646f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DAGLB ATG2A REV3L SRGAP3 HECTD1 FILIP1L

6.80e-0518716460099def970fbc828756fbf853eca2ce77b8cd342
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D25 ITGA7 VIPAS39 FAM13A SMARCA1 DAAM2

6.80e-051871646f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D25 ITGA7 VIPAS39 FAM13A SMARCA1 DAAM2

6.80e-0518716463ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PKP4 ITPR1 RALGPS1 RIMBP2 LNX1

7.01e-0518816462ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OBSCN REV3L DENND2B PREX2 PTPN13 DAAM2

7.01e-051881646997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PKP4 CKB RALGPS1 RIMBP2 LNX1

7.01e-0518816463cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A PKP4 ITPR1 RALGPS1 RIMBP2 LNX1

7.22e-051891646f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 BTBD3 PLEKHG3 SMARCA1 DAAM2 FILIP1L

7.22e-051891646de51fbd6fdb24fc4549393cf41a020005444b2aa
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HAUS5 AK9 LRRK1 TRANK1 PIK3C2B CEP250

7.22e-051891646bccb3481ffed597c845fe860da658505316105b5
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IFT140 SHROOM2 DENND2B PREX2 KCNN2 LNX1

7.22e-051891646b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

DENND2A OBSCN PREX2 SMTN SLC7A2 DAAM2

7.22e-051891646d7ed96add29f219183c802895fbff519b627f635
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 BTBD3 PLEKHG3 SMARCA1 DAAM2 FILIP1L

7.43e-0519016461d8e169d2448a34180c415843bb49aa45ed540c5
ToppCellIPF-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SH3TC2 BACH2 CKB SLC7A2 PIK3C2B ATP2A3

7.87e-051921646e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ITGA7 CKB GNG12 DAAM2 FILIP1L

7.87e-051921646992d08092edbc68c47b945deb8708379738c239a
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

DYNC2H1 ABCC5 DENND2B ITPR1 PTPN13 RIMBP2

7.87e-051921646d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLF1 PKP4 CCDC85A BTBD3 PIK3C2B CTNND2

8.10e-05193164602f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLF1 PKP4 CCDC85A PREX2 PIK3C2B CTNND2

8.10e-051931646af5108260783e69a7d67896c5bf64f862525926d
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLF1 PKP4 CCDC85A BTBD3 PIK3C2B CTNND2

8.10e-0519316465122b1ffba42de190061be34ecdc6176f84e56a3
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA7 BTBD3 PLEKHG3 SMARCA1 DAAM2 FILIP1L

8.10e-0519316460266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA7 SMTN CKB NRXN1 TRIM47 FILIP1L

8.10e-0519316467386fadc13a437f3b0c99b5d116cd3c5f893529c
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLF1 PKP4 CCDC85A PREX2 PIK3C2B CTNND2

8.33e-0519416460b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLF1 PKP4 CCDC85A PREX2 PIK3C2B CTNND2

8.33e-05194164658f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLF1 PKP4 CCDC85A PREX2 PIK3C2B CTNND2

8.33e-051941646bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LCA5 DYNC2H1 SLC7A2 CCDC78 CCDC180 CCDC40

8.57e-051951646e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LCA5 DYNC2H1 SLC7A2 CCDC78 CCDC180 CCDC40

8.82e-05196164627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A OBSCN PREX2 SMTN DAAM2 FILIP1L

9.06e-051971646f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A OBSCN PREX2 SMTN DAAM2 FILIP1L

9.06e-05197164641dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

ABCC3 LRRK1 NEB EHHADH PLEKHG3 FILIP1L

9.06e-05197164615b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

ABCC3 LRRK1 NEB EHHADH PLEKHG3 FILIP1L

9.06e-051971646a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LCA5 DYNC2H1 AK9 CCDC78 CCDC180 CCDC40

9.32e-051981646ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CKB NRXN1 CTNND2 TRIM47 LNX1 SYMPK

9.32e-05198164601d563ccdc0da02dac04169e713844fecb4233a1
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA7 ITPR1 SMTN CKB DAAM2 FILIP1L

9.32e-0519816461e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

LCA5 CCDC186 REV3L RAD50 ANKIB1 GOLGA4

9.58e-051991646fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CKB NRXN1 CTNND2 TRIM47 LNX1 SYMPK

9.58e-05199164604e5cfb85c681fd3f4c1151062e4a0f460b55d5f
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

BACH2 PKP4 FAM98B PTPN13 PDS5A CDT1

9.58e-051991646358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CENPF CTDSP2 CKB UHRF1 CDT1 LNX1

9.58e-05199164653b3d35767889a152f1f38e8f6f0ba8f7a7690f2
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_2-VSMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAP7D3 ITGA7 SMTN CKB SLC7A2 FILIP1L

9.85e-052001646fc802dd73f048881d9ddafd1b79ab3ca654510e2
ToppCellcellseq2-Mesenchymal-Myocytic-Myocytic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAP7D3 ITGA7 SMTN CKB SLC7A2 FILIP1L

9.85e-052001646cffddb39960cd611428397c1ec4023192e8af5a7
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CENPF HAUS5 SAMD9L UHRF1 ALAS1 CDT1

9.85e-0520016460cf7208eab0dc58fbea35e256c5cb55cdd4a4928
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DENND2A OBSCN PREX2 SMTN PLEKHG3 DAAM2

9.85e-0520016460c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLF1 GIT1 CCDC85A BTBD3 SAMD9L ZNF518B

9.85e-052001646bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellcellseq2-Mesenchymal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAP7D3 ITGA7 SMTN CKB SLC7A2 FILIP1L

9.85e-0520016466b558cce0d6047c7e85f428adff80c5ca3084ea4
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PKP4 PREX2 SAMD9L PIK3C2B CTNNA1 FILIP1L

9.85e-0520016462d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-dn_T|Int-URO / Disease, condition lineage and cell class

CAD ABCC5 CBR3 ASB7 LNX1 CCDC180

9.85e-052001646020439d9e70fff7246650ab0e9105236688c3ec3
ToppCellcellseq2-Mesenchymal-Myocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAP7D3 ITGA7 SMTN CKB SLC7A2 FILIP1L

9.85e-052001646e60aebd20be8012fa2febf6585ed34ebd64ec9b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND2A OBSCN PREX2 SMTN PLEKHG3 DAAM2

9.85e-052001646522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLF1 PKP4 PREX2 PIK3C2B ZNF518B CTNNA1

9.85e-052001646f15fffefe372005c33e31845982e2d2714ac26af
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DENND2A OBSCN PREX2 SMTN PLEKHG3 DAAM2

9.85e-05200164694f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC7A2 PTPN13 MYH14 SRGAP3 CTNNA1 HECTD1

9.85e-052001646ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

LCA5 PLCXD2 PTPN13 RALGPS1 FILIP1L

1.53e-041371645a1e34ebbeda3d5a4f14917282d44fcb4dcbf3133
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_only / Treatment groups by lineage, cell group, cell type

DENND2A PHB2 LMBR1L HERC2 ATP2A3

1.59e-0413816456ddd50e44a3914596b4cd61ae64a987119fe7979
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DENND2A IFT140 CCDC85A DAAM2 SPIN2B

1.64e-04139164539f3c28f89c37bb8cc049c56d2948ea906fb3d86
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DENND2A IFT140 CCDC85A DAAM2 SPIN2B

1.64e-0413916454efab4421e3448880a1dcf981f6a65131b038010
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR35 CDT1 LRRC75A FILIP1L SYMPK

1.81e-041421645d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR35 CDT1 LRRC75A FILIP1L SYMPK

1.81e-041421645a05b320cf182b2aaf18df7c40045dc65b659bf20
Drug5211181; Up 200; 12uM; MCF7; HT_HG-U133A_EA

GIT1 DYNC2H1 HAUS5 ITPR1 CKB PDE12 SGPL1 RALGPS1 RASSF1 SYMPK

1.58e-0619516410834_UP
DrugAmphotericin B [1397-89-3]; Down 200; 4.4uM; MCF7; HT_HG-U133A

IFT140 GIT1 HAUS5 MAP3K4 STK11 PACS2 BICRAL ABCC10 SYMPK

1.19e-0519416493303_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A

SH3TC2 GIT1 LRRK1 ITPR1 PCNX2 STK11 FAM13A CEP250 BICRAL

1.19e-0519416494524_DN
DrugStrophanthidin [66-28-4]; Down 200; 9.8uM; PC3; HT_HG-U133A

R3HCC1 ABCC5 SHROOM2 CBR3 BTBD3 DUS2 PLEKHG3 CEP250 UBAC1

1.19e-0519416495826_DN
DrugCyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A

DYNC2H1 ACOX1 HAUS5 ZNF227 MAP3K4 SMTN EHHADH RASSF1 ATP2A3

1.35e-0519716495340_DN
DrugJosamycin [16846-24-5]; Down 200; 4.8uM; PC3; HT_HG-U133A

PXMP4 ABCC3 IFT140 LRRK1 DIP2A SMPDL3B CTNND2 FILIP1L SYMPK

1.35e-0519716494631_DN
DrugAmoxicillin [26787-78-0]; Up 200; 11uM; PC3; HT_HG-U133A

SLC37A1 CENPF P3H3 HAUS5 LRRK1 MYH14 CTNND2 CROCC FILIP1L

1.46e-0519916496285_UP
DrugVincamine [1617-90-9]; Up 200; 11.2uM; HL60; HT_HG-U133A

IFT140 GIT1 ODF1 NEB CBR3 CKB STK11 PDE12 ASB7

1.46e-0519916492367_UP
DiseaseShort Rib-Polydactyly Syndrome

IFT140 DYNC2H1 WDR35

4.63e-05131643C0036996
DiseaseSaldino-Noonan Syndrome

IFT140 DYNC2H1 WDR35

5.87e-05141643C0036069
DiseaseMajewski Syndrome

IFT140 DYNC2H1 WDR35

5.87e-05141643C0024507
DiseaseShort rib-polydactyly syndrome, Verma-Naumoff type

DYNC2H1 WDR35

3.04e-0451642C0432197
Diseasetriacylglycerol 58:10 measurement

NRXN1 LNX1 MUSK

8.89e-04341643EFO_0010437
DiseaseJeune thoracic dystrophy

IFT140 DYNC2H1

1.63e-03111642C0265275
DiseaseCharcot-Marie-Tooth disease

SH3TC2 MARS1 SGPL1

1.65e-03421643cv:C0007959
Diseaselevel of Sphingomyelin (d34:2) in blood serum

SGPL1 MUSK

2.30e-03131642OBA_2045174
Diseasereading and spelling ability

NEB CCDC85A PTPN13 NRXN1 SRGAP3

2.40e-031661645EFO_0005301
DiseaseWilliams-Beuren syndrome (implicated_via_orthology)

EIF4H CLIP2

3.07e-03151642DOID:1928 (implicated_via_orthology)
Diseasemyelodysplastic syndrome (implicated_via_orthology)

PRPF8 SAMD9L

3.07e-03151642DOID:0050908 (implicated_via_orthology)
DiseaseCiliopathies

LCA5 DYNC2H1 WDR35 CCDC40

3.36e-031101644C4277690
Diseaseplatelet component distribution width

DENND2A SH3TC2 ABCC5 CTDSP2 CKB TRANK1 GNG12 PLEKHG3 PDS5A MUSK CCDC40

3.43e-0375516411EFO_0007984
Diseaselower body strength measurement

PCNX2 ASB7

3.50e-03161642EFO_0007999
Diseasesevere acute respiratory syndrome, COVID-19

ABCC3 P3H3 CCDC85A PREX2 AXDND1 NRXN1 SRGAP3 RIMBP2

3.66e-034471648EFO_0000694, MONDO_0100096
Diseasedelta-5 desaturase measurement, response to polyunsaturated fatty acid supplementation

UBXN6 MUSK

3.95e-03171642EFO_0007764, EFO_0009131
Diseaseplasma beta-amyloid 1-40 measurement

RNF214 PDS5A

3.95e-03171642EFO_0005659
DiseaseCongenital Fiber Type Disproportion

ITGA7 CCDC78

4.43e-03181642C0546264
DiseaseChronic myeloproliferative disorder

CENPF CDT1

4.93e-03191642C1292778

Protein segments in the cluster

PeptideGeneStartEntry
RLLRKSIDAEVRELV

PKP4

621

Q99569
TAKLLLSRENIREVI

BACH2

96

Q9BYV9
SRKRESELLLFTERL

CCDC186

581

Q7Z3E2
ITIRRKAELAATLGL

CDX2

211

Q99626
LAIIRERSSCVKILL

ASB7

156

Q9H672
ELARVLRSVFVSERK

CDT1

456

Q9H211
KIEEVRAILRTLLEA

CYP2W1

236

Q8TAV3
SILRRETLNAKEIVV

BTBD3

271

Q9Y2F9
IEDAVHVLLKTRRIL

ANKIB1

646

Q9P2G1
EILRLRERLLSASKE

CLIP2

541

Q9UDT6
ATLIIDILSEAKRRQ

GIT1

341

Q9Y2X7
ESRILVLTELLERKA

ASB6

46

Q9NWX5
LCSRLEKEAARIELV

CCDC180

1061

Q9P1Z9
ASLLLERRVIFVADK

DENND2B

891

P78524
ERRVIFVADKLSTLS

DENND2B

896

P78524
ARCLIRRKIVTLDSL

SLC7A2

11

P52569
ELVLLREKSRALEAS

CCDC154

381

A6NI56
ITALIRREVKAAVSR

CDAN1

981

Q8IWY9
SLVVKLADTDRERAL

CELF6

206

Q96J87
LVRLLRKTTDLEIRE

CTNND2

641

Q9UQB3
RELVLAVSKVEELTR

TP53BP2

226

Q13625
ADLRLIEIKSTTLRV

ATP2A3

161

Q93084
ETVLRRIKVTFLDTV

ATG2A

161

Q2TAZ0
EVGVIAKALVRLLRS

AP3B2

336

Q13367
AAEALTREFSVLKIR

R3HCC1

366

Q9Y3T6
IVTIITAAKRDLALV

PDS5A

381

Q29RF7
AREVIEALLRKFLVV

RASSF1

226

Q9NS23
ASIERALLRECSVIK

QSER1

176

Q2KHR3
KVLASLIIRLALAET

RAD50

1206

Q92878
VREILTAQTLKIRAE

RALGPS1

106

Q5JS13
GAKLLLEVSERVRTL

P3H3

531

Q8IVL6
LRKSRILVLDEATAA

ABCC3

1441

O15438
IRARIFLIASKELEL

NCSTN

656

Q92542
RLRATAERVKALESA

KIF5B

866

P33176
VKTVRERLAIALIAD

MBD3L1

161

Q8WWY6
AILLASRELVRSKRL

DAAM2

781

Q86T65
DARVKLVTELLSGIR

ABCC10

456

Q5T3U5
IFKDLSIRSVRLVRD

EIF4H

61

Q15056
LDAVTRGLKTALVER

GPD2

86

P43304
TLVFEVELLKIERRT

FKBP2

126

P26885
IRVLSDVAKSRAIAI

ITPR1

1546

Q14643
LESVRILKSAEGRVL

ALAS1

486

P13196
RRAIEKLAVEALSSL

CKB

151

P12277
LIEAKFRVERIATLR

LRRK1

761

Q38SD2
RTRILELESSLEKSL

GOLGA4

566

Q13439
LIADDTRVVVDLLKL

HERC2

3541

O95714
TALVVAVVARKLELT

KCNN2

386

Q9H2S1
RLTRAVLRDLTDILK

LRRC75A

241

Q8NAA5
AAVLEIVERLTKLIR

SMPDL3B

106

Q92485
LRRVLDELTLSKTDL

KRT13

211

P13646
DSFVREIVARLLSKI

FSIP2

4306

Q5CZC0
LITSGRRILADEALK

EHHADH

151

Q08426
SRVVLRVLEAAVAAK

EIF2B1

131

Q14232
KTRLALEAEVSELRA

MYH14

1241

Q7Z406
RLTLLALLDRTEDIK

PCNX2

826

A6NKB5
LRVIRTAVEKLSRAE

PDE12

11

Q6L8Q7
AVRAKVSRLVAAVVL

KISS1R

256

Q969F8
LTEVSRSEAVALLKR

LNX1

566

Q8TBB1
DTDLVTKRILSARLL

LCA5

96

Q86VQ0
ARDLIKLLARSVSFE

KRR1

116

Q13601
RKLELEAAVTRLRAE

HAUS5

76

O94927
TRRAVTLRVLLKDAL

MPND

71

Q8N594
TLRLELDAGRVKLTV

NRXN1

766

Q9ULB1
VALLRRFKVSDEVLD

PACS2

256

Q86VP3
SLRSLERKAIRAIED

ODF1

86

Q14990
LRLLEVLISKRDTDS

FAM13A

1006

O94988
SRKRRLAELTVDEFL

NOC2L

6

Q9Y3T9
SLLIRRELTERAKDF

PHB2

161

Q99623
LVRFLLKRAVSDLRV

PIK3C2B

936

O00750
SLSLVLRKTLDREEI

PCDHA13

191

Q9Y5I0
RSGLLVLVIRAASKE

OBSCN

6161

Q5VST9
ASLEILRKELTRAVS

PROX2

221

Q3B8N5
VRISDIGLADLRSKL

ABCC5

1256

O15440
ILAGVISDRLEKRAS

SLC37A1

381

P57057
RETLLARLVDSIKDF

DYNC2H1

441

Q8NCM8
RVKELLTLIRSDAVA

ACOX1

591

Q15067
SARVTELGLAVKRLE

CROCC

396

Q5TZA2
AVALIRKLIAVLESI

HECTD1

961

Q9ULT8
LRLAVKLDITAEILA

BPIFA1

151

Q9NP55
EERASLSRDKRLALV

BICRAL

801

Q6AI39
KSLEIRTLAVERLLE

CTNNA1

16

P35221
LRLEASIERIKVSKA

GNG12

21

Q9UBI6
RSLKVFELDLVTLRS

CENPF

2196

P49454
RRVIFIADKLSILSK

DENND2A

766

Q9ULE3
IITQARREDALVLTK

CTDSP2

6

O14595
LLVAEKSRRQTILEL

FILIP1L

161

Q4L180
SVTNLEDLKRRILRV

DAGLB

501

Q8NCG7
LRELSEELRVSKVFA

EPM2AIP1

391

Q7L775
RLIELIRSAKEFIVL

FRMPD3

111

Q5JV73
VARLELDAIELTRKL

AXDND1

741

Q5T1B0
DKRLALIATILDRVR

CCDC40

1101

Q4G0X9
ILEEDLRTARSALKL

CEP250

1376

Q9BV73
LKSEILRLESRVLEL

CCDC78

86

A2IDD5
LLAAREDLSKIIRTS

FAM98B

271

Q52LJ0
ELIRSLRRAEAEKVS

CCDC85A

51

Q96PX6
SERIALTNKIRVIFE

DNAH14

1601

Q0VDD8
AEAATKILTELRRLA

MAP7D3

596

Q8IWC1
IVLCETFRKRLVLSV

MCHR1

381

Q99705
VTVLSRILARRLDEK

CBR3

201

O75828
GAVVILRKDSASRLV

ITGA7

336

Q13683
VLEEKVLRLTRTVLD

EMILIN2

186

Q9BXX0
TRLLRSKEAAAAVDI

DIP2A

1106

Q14689
LSLVKRIERTGIAAI

DUS2

166

Q9NX74
LAKELVEVREALSRA

CROCCP3

141

Q8IVE0
TALVFLDKRIVAARL

SCAP

1011

Q12770
KREALVVVTENLRLS

IFT140

241

Q96RY7
ERLTTLEAKVLLLEA

COL26A1

141

Q96A83
AASKTVRLVIGRVLE

PTPN13

1856

Q12923
ISRVEESALRALREK

PPEF2

551

O14830
KLRTDLRFIAELTIV

UPF2

261

Q9HAU5
ILSLERLRQAVTVKE

KIF13A

1356

Q9H1H9
RRSVIEISRALKELF

MAP3K4

791

Q9Y6R4
LSLQREKIIARVSID

PNPLA8

346

Q9NP80
DTRSLEARIIALSVK

MRPS15

121

P82914
VDTIAKRRAELILER

AK9

1191

Q5TCS8
IRDIARSTLAKIIED

UTP20

1861

O75691
STAVELVRLRSLEAK

RIMBP2

546

O15034
IKSAAVAERERVSRL

TRIM47

256

Q96LD4
RIVERAEIKLRLDSI

SMARCA1

631

P28370
LEFIRSTVLKDVLRT

TBC1D25

281

Q3MII6
LVKTFTAAVRAELIR

LMBR1L

451

Q6UX01
ESALSTRDRLLLDKI

PLEKHG3

706

A1L390
RASEVRKLILFLTDE

SAMD9L

521

Q8IVG5
ETLEALILKELSVIR

POLR3A

746

O14802
IESISRKLQVLREAR

SHROOM2

1441

Q13796
AVRTELRIFNKLTEL

SH3TC2

1121

Q8TF17
DERVLSLKILSDRVA

SPIN2A

101

Q99865
VLDSETLCRRAVKIL

STK11

66

Q15831
LRKIEAEIVRIACSL

SGPL1

181

O95470
LCREVLRLTKLVVDS

PRPF8

546

Q6P2Q9
LLFEIASARIEERKV

SNX20

76

Q7Z614
AEILSLESRKELLVL

RNF214

351

Q8ND24
LRSEAVERLSVLRTK

UBXN6

306

Q9BZV1
RLLSAILRVSEVESR

XPO4

606

Q9C0E2
ERSLKLLFETRDISL

REV3L

2871

O60673
VRLSQISEDVIRLFK

SRGAP3

126

O43295
VSIFDISIARRKDLA

THAP9

656

Q9H5L6
FIRLESRTLAEIAKA

PSPC1

121

Q8WXF1
RKLILFLETTLSERA

PLCXD2

241

Q0VAA5
STREAELKLRLRLVE

SOGA3

581

Q5TF21
DERVLSLKILSDRVA

SPIN2B

101

Q9BPZ2
LRLRVCVLSELQKTE

PREX2

21

Q70Z35
RTLSKEILFRELEVR

VIPAS39

206

Q9H9C1
LDTAIRVALAVAVLK

PILRB

186

Q9UKJ0
LLVRTDKRSDSLIRV

SLF1

131

Q9BQI6
IALAVLSTELAVRKL

CAD

876

P27708
KAEVLSFILEDVRAR

SYMPK

601

Q92797
IKRFEVLVIRLRDSL

MYO18B

1986

Q8IUG5
FAELISAIKRTLARL

TMEM87B

286

Q96K49
VDSLSRLTKVEELRR

UHRF1

16

Q96T88
KDVAVVFSREELRLL

ZNF227

26

Q86WZ6
RDFQTELRKILVSLI

UBAC1

146

Q9BSL1
LLDRQSRSVVDVLKR

TRANK1

276

O15050
LVISIRVKELVSREL

TUT7

571

Q5VYS8
FEIRSLRDSRALIEK

WDR35

666

Q9P2L0
LSRVLFALSRLAVEK

PXMP4

131

Q9Y6I8
LEKVRIRDALRSILT

MARS1

696

P56192
KLLEVTADLAERRRI

SMTN

16

P53814
SELSLLEERFRVAIK

POLR2J

96

P52435
ISDLLSEAKLRLSRI

ATP6V1E2

91

Q96A05
AVATRAGLLLDTIKR

UNC79

1106

Q9P2D8
SIELLRRKIAQLIES

ZNF518B

661

Q9C0D4
VADLTESILKNLRRV

LDHAL6A

256

Q6ZMR3
VRKEEVLILRSQLVS

MYO5A

1261

Q9Y4I1
VKDRVIDSRLQLFIT

MUSK

261

O15146
SLEVVRAKRAGELLS

NEB

3401

P20929