Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion binding

TRAF4 CRYZ TES RNF31 LIN28B KDM5C SF3A3 RNF41 TNKS ADAM8 TET3 ZMAT1 RBM20

2.48e-058917513GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

TRAF4 CRYZ TES RNF31 LIN28B KDM5C AOX1 SF3A3 RNF41 TNKS ADAM8 TET3 ZMAT1 RBM20

1.20e-0411897514GO:0046914
DomainZnf_C2H2_matrin

SF3A3 RBM20

9.70e-0412732IPR000690
Domain-

TRAF4 RNF41

1.33e-03147323.90.890.10
DomainSIAH-type

TRAF4 RNF41

1.75e-0316732IPR013323
DomainPoly(ADP-ribose)pol_cat_dom

PARP8 TNKS

1.97e-0317732IPR012317
DomainPARP_CATALYTIC

PARP8 TNKS

1.97e-0317732PS51059
DomainPARP

PARP8 TNKS

1.97e-0317732PF00644
Domain-

PARP8 TNKS

1.97e-03177323.90.228.10
DomainZF_MATRIN

SF3A3 RBM20

2.21e-0318732PS50171
DomainTyr_Pase_AS

PTPRS SSH2 PTPRT

2.93e-0373733IPR016130
Domainzf-RanBP

RNF31 CAPN15

3.31e-0322732PF00641
DomainZnf_MYND

ZMYND19 SMYD5

3.31e-0322732IPR002893
DomainZF_MYND_1

ZMYND19 SMYD5

3.31e-0322732PS01360
DomainZF_MYND_2

ZMYND19 SMYD5

3.31e-0322732PS50865
DomainZnF_RBZ

RNF31 CAPN15

3.61e-0323732SM00547
DomainZF_RANBP2_2

RNF31 CAPN15

3.61e-0323732PS50199
DomainWGR_domain

PARP8 TNKS

3.93e-0324732IPR008893
DomainTRAF-like

TRAF4 RNF41

3.93e-0324732IPR008974
DomainZF_RANBP2_1

RNF31 CAPN15

3.93e-0324732PS01358
DomainZnf_RanBP2

RNF31 CAPN15

4.26e-0325732IPR001876
DomainTYR_PHOSPHATASE_1

PTPRS SSH2 PTPRT

4.65e-0386733PS00383
DomainTYR_PHOSPHATASE_2

PTPRS SSH2 PTPRT

4.80e-0387733PS50056
DomainTYR_PHOSPHATASE_dom

PTPRS SSH2 PTPRT

4.80e-0387733IPR000387
Domain-

PTPRS SSH2 PTPRT

5.61e-03927333.90.190.10
DomainZnF_U1

ZMAT1 RBM20

5.71e-0329732SM00451
DomainZnf_U1

ZMAT1 RBM20

5.71e-0329732IPR003604
DomainProt-tyrosine_phosphatase-like

PTPRS SSH2 PTPRT

6.87e-0399733IPR029021
Pubmed

RXXPEG motif of MERIT40 is required to maintain spindle structure and function through its interaction with Tankyrase1.

BABAM1 TNKS

4.59e-06275230571846
Pubmed

WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer.

BABAM1 TNKS

1.37e-05375237248434
Pubmed

Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BOC ATXN7L2 RNF31 KLHL36

3.54e-058575415449545
Pubmed

MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy.

BABAM1 TNKS

4.57e-05575226027929
Pubmed

Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.

BABAM1 TNKS

6.84e-05675226845027
Pubmed

The IA-2 interactome.

PTPRS PTPRT

6.84e-05675216273344
Pubmed

The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway.

TRAF4 RNF31

2.04e-041075237081115
Pubmed

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.

GGNBP2 RAB34

2.49e-041175236737727
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

ERP44 CWC27 RNF41 GFER MOV10

4.72e-0429875532353859
Pubmed

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.

RAB34 RNF41

4.73e-041575224056301
Pubmed

Family-wide analysis of poly(ADP-ribose) polymerase activity.

PARP8 TNKS

5.40e-041675225043379
Pubmed

Structure of the human activated spliceosome in three conformational states.

CWC27 SF3A3

5.40e-041675229360106
Pubmed

Identification and characterization of proteins interacting with Traf4, an enigmatic p53 target.

TRAF4 SARDH

5.40e-041675216969126
Pubmed

Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway.

ZMYND19 SMYD5

5.40e-041675225077969
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

GGNBP2 BABAM1 LIN28B OSGEPL1 KDM5C SF3A3 C10orf90 SSH2 CRAMP1 CAPN15

5.50e-041327751032694731
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

RNF31 PTPRS CWC27 KDM5C SF3A3

5.90e-0431375538270169
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ERP44 CEP72 SSH2 CCDC85A MOV10 FAN1

6.94e-0449375615368895
Pubmed

Genome-wide association study link novel loci to endometriosis.

KSR2 IL33

7.66e-041975223472165
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

TES ERP44 CEP72 CWC27 RNF41 GFER MOV10

1.21e-0375475733060197
Pubmed

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.

PTPRS SCRG1

1.44e-032675236178190
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

GUCY1A2 SYNE1 TET3 CRAMP1

1.64e-0323375437704626
Pubmed

The protein kinase complement of the human genome.

KSR2 STKLD1

1.67e-032875212471243
Pubmed

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.

CST3 IL33

1.67e-032875220534741
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

FAM171A1 BABAM1 CEP72 PTPRS SSH2 RBM20 PTPRT FAN1

1.89e-03104975827880917
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

CEP104 FAM171A1 KLHL36 OSGEPL1 USPL1 RBM20 STAB1

2.12e-0383275736724073
CytobandEnsembl 112 genes in cytogenetic band chr17q11

TLCD1 TRAF4 RAB34 SSH2

1.93e-04171764chr17q11
Cytoband17q11.2

TLCD1 RAB34 SSH2

8.28e-0411076317q11.2
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP8 TNKS

9.15e-0417482684
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRS PTPRT

1.40e-0321482813
GeneFamilyZinc fingers MYND-type

ZMYND19 SMYD5

1.40e-032148287
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RNF31 CAPN15

1.40e-032148289
GeneFamilyFibronectin type III domain containing

BOC PTPRS PTPRT

8.79e-03160483555
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TLCD1 AOX1 CST3 SCRG1 IL33

6.48e-0615376595b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TLCD1 AOX1 CST3 SCRG1 IL33

6.48e-06153765b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TLCD1 AOX1 CST3 SCRG1 IL33

6.48e-061537653ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMYND19 CEP72 CST3 ADAM8 CFAP65

1.14e-05172765eba1568d4307e91c94fc616549057cbed8df5840
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SELP SCRG1 SMYD5 IL33 CCDC85A

1.31e-051777651921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMYND19 BOC RAB34 AOX1 SARDH

1.99e-051937657c0d84b92470bfda2db1e5007feee7c1235a0a78
ToppCell367C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BOC AOX1 CST3 SCRG1 IL33

2.30e-051997652aed8f4a225a3762a5e7ce99aacad9b2a37d61f1
ToppCell367C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BOC AOX1 CST3 SCRG1 IL33

2.30e-05199765c40ca26345753a2197bd9389d7323f7491c1e11d
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KSR2 ADAM8 RBM20 STAB1

4.66e-05116764df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 SCRG1 SSH2 ADAM8

1.02e-04142764bf3537bec0eca9f90c00df9ba840c371f1c9856e
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HIPK4 BTAF1 POLG2 STAB1

1.05e-041437647adc34d8ad11e57950a5a258ae9bf8f52259385a
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAB34 LIN28B MAP10 STAB1

1.08e-04144764f769be4da268980ea7c06d7097ec39d06777e675
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB34 OSGEPL1 MAP10 CFAP65

1.43e-04155764441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PARP8 RBM20 PTPRT CFAP65

1.47e-0415676410d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAB34 CST3 SMYD5 STKLD1

1.47e-04156764af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TLCD1 AOX1 CST3 SCRG1

1.51e-041577640551442ae14685d8fe5729e3960c6324b1e05e4d
ToppCellfrontal_cortex-Non-neuronal-astrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TLCD1 AOX1 CST3 SCRG1

1.51e-04157764803af734d7f775d294391e2b84e472a732e18cef
ToppCellfrontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TLCD1 AOX1 CST3 SCRG1

1.51e-041577649aa5304a9704da6dd4eda7d6940494b00e38b2e8
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIPK4 SYNE1 SCRG1 ADAM8

1.82e-04165764eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPRS AOX1 CST3 SCRG1

2.00e-0416976447fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPRS AOX1 CST3 SCRG1

2.00e-04169764e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCelldroplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB11 CARF EHF SLFN5

2.04e-04170764545c755b057871b7a22221a049a63a61713dad1d
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB34 BTAF1 TSTD2 SSH2

2.14e-04172764574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB34 BTAF1 TSTD2 SSH2

2.14e-041727641627fa7035b0e0bbc82a1c0f000d8231254c680a
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOX1 CST3 ZBTB41 ADAM8

2.18e-0417376428c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SLFN5 CCDC85A STAB1 CFAP65

2.23e-04174764b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAB34 PARP8 CST3 ADAM8

2.28e-041757644655d3daa95e8ffa7d5ee4180de06b2fec361bfb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 SCRG1 ADAM8 C1orf94

2.33e-04176764ef0ff02897104e938c8a632357d8f1a6f014e68a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 SCRG1 ADAM8 C1orf94

2.33e-04176764da0983929fa682a68e536c298a2d7add188b7563
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

BOC AOX1 IL33 CCDC85A

2.33e-04176764510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCellprimary_visual_cortex-Non-neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TLCD1 CST3 SCRG1 IL33

2.33e-041767642c92f3f55d668cfe80051b5128160a6dc3aec4e8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GUCY1A2 RPS6KA5 IL33 OPRK1

2.49e-041797641ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SELP IL33 CCDC85A STAB1

2.54e-041807645861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CWC27 CARF CST3 POLG2

2.70e-04183764ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCellPND10-Immune-Immune_Myeloid-Dendritic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CWC27 CARF CST3 POLG2

2.70e-04183764e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CWC27 CARF CST3 POLG2

2.70e-04183764263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCellDendritic_Cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CST3 SCRG1 ADAM8 STAB1

2.70e-04183764dd09e39e8ca282ff0f470e0652d519e190badd0b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LCA5 RPS6KA5 NGEF OPRK1

2.70e-0418376401ad18f198195ce341bae01a1c8c253cc4607766
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELP IL33 CCDC85A STAB1

2.70e-04183764a644258ba90acc62d571623e429d72ffc4b69203
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SELP FAM171A1 IL33 CCDC85A

2.70e-04183764c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC RAB34 PTPRS AOX1

2.82e-041857649faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

BOC GUCY1A2 PTPRS AOX1

2.82e-04185764fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCelldroplet-Bladder-nan-24m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELP SLFN5 CCDC85A STAB1

2.82e-0418576490caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SELP FAM171A1 NGEF IL33

2.82e-04185764a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES SYNE1 PARP8 SLFN5

2.88e-0418676471e87c4c755ab607689cb050f5a363cb520a0f53
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LCA5 ZNF474 PTPRT CFAP65

2.88e-0418676476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GUCY1A2 SYNE1 RBM20 IL33

2.88e-041867644780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD1 CST3 NGEF SCRG1

2.88e-04186764ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PTPRS AOX1 PROK1

2.88e-041867647582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

SELP FAM171A1 IL33 CCDC85A

2.94e-04187764e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

SELP FAM171A1 IL33 CCDC85A

2.94e-0418776481affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell3'_v3-blood-Myeloid_Dendritic|blood / Manually curated celltypes from each tissue

TRAF4 RAB34 PTPRS CST3

3.00e-04188764239a2162a21d3339da7c1884ab76286346fbf97f
ToppCell3'_v3-blood-Myeloid_Dendritic-DC1|blood / Manually curated celltypes from each tissue

TRAF4 RAB34 EHF CST3

3.00e-04188764411d4dd5c9dee7ebd8db352640cf009e7b033ba9
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

SELP FAM171A1 SLFN5 STAB1

3.06e-041897649a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TLCD1 RAB34 CST3 IL33

3.12e-0419076478cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

BOC GUCY1A2 PTPRS AOX1

3.12e-041907647dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 PARP8 SLFN5 SSH2

3.12e-04190764d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SELP FAM171A1 IL33 CCDC85A

3.12e-0419076407b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell343B-Endothelial_cells-Endothelial-A_(Artery)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SELP FAM171A1 IL33 STAB1

3.12e-04190764ac2eb1e51459d187095152e0cd41ae54c1025c6f
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TLCD1 RAB34 CST3 IL33

3.12e-04190764e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCell(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

SELP FAM171A1 SLFN5 STAB1

3.12e-04190764ff083168d609957d00888f31b3488d6d56c902b4
ToppCell343B-Endothelial_cells-Endothelial-A_(Artery)|343B / Donor, Lineage, Cell class and subclass (all cells)

SELP FAM171A1 IL33 STAB1

3.12e-041907646010f16378f2d9cde37c7e7db6a7d9666edaddcc
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|343B / Donor, Lineage, Cell class and subclass (all cells)

SELP FAM171A1 IL33 CCDC85A

3.18e-0419176427a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SELP FAM171A1 IL33 CCDC85A

3.18e-041917641dfcff08e01e6a695953334342bcfde04ba005ad
ToppCelldroplet-Kidney-nan-3m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC SLFN5 IL33 CCDC85A

3.24e-0419276485be54c2cba8eab4c6ef2a85a526f7a9db4cfe73
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

EHF KSR2 ZMAT1 OPRK1

3.24e-04192764b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC SLFN5 IL33 CCDC85A

3.24e-0419276431a9142d97b690992aabee1a181650deb1a44253
ToppCellBLOOD--(3)_DC_(cDC+pDC)| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TRAF4 RAB34 PTPRS CST3

3.24e-04192764e290c55a1321e9e577f49e8ba20501b2c8150044
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

BOC GUCY1A2 PTPRS AOX1

3.24e-04192764d21f0f577156f17c899b08871046a26b88aea011
ToppCellCOVID-19_Severe-CD8+_T_activated|World / disease group, cell group and cell class

SYNE1 PARP8 SLFN5 RBM20

3.31e-04193764ddc1db516568e03be8e82b2ca770c67756418185
ToppCell18-Distal-Mesenchymal-Cartilage|Distal / Age, Tissue, Lineage and Cell class

BOC CST3 NGEF SCRG1

3.31e-0419376452f3d1bb8d8ca91ba12439d46392f377928ff8f8
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELP FAM171A1 IL33 STAB1

3.31e-041937647261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TES SYNE1 PARP8 SLFN5

3.37e-041947646be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SELP IL33 CCDC85A STAB1

3.37e-04194764efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC GUCY1A2 PTPRS IL33

3.37e-04194764c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GUCY1A2 PTPRS SYNE1 AOX1

3.37e-0419476460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SELP FAM171A1 IL33 CCDC85A

3.37e-04194764fc2e0081005c0c496e41197a2d06e4a37708221f
ToppCell(0)_Normal/No_Treatment-(1)_VE-Cad+_vascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

SELP FAM171A1 SLFN5 STAB1

3.44e-04195764e8ab3122f81cb22920becd6611cbd9f00db19d50
ToppCelldroplet-Kidney-nan-21m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC SLFN5 IL33 CCDC85A

3.44e-0419576437d22a6448db1f83d098018fbb75a6dd8d9be302
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ASB11 AOX1 PTPRT OPRK1

3.44e-04195764d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC SLFN5 IL33 CCDC85A

3.44e-0419576437592b7ad912b381b1edc77f4032983f26e0aa5b
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ASB11 AOX1 PTPRT OPRK1

3.44e-0419576419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELP ZMAT1 IL33 STAB1

3.44e-041957649ad4981c4d157edc752de206ab0d754aa14beab8
ToppCellT_cells-GZMK+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SYNE1 PARP8 SLFN5 ADAM8

3.44e-04195764003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC GUCY1A2 PTPRS IL33

3.44e-041957643c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellLAM-Endothelial-VasEndo-2|LAM / Condition, Lineage and Cell class

SELP FAM171A1 IL33 CCDC85A

3.44e-04195764bd11d771938251c091a50d559a2c38d1c4a04033
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

SELP FAM171A1 SLFN5 STAB1

3.44e-041957646b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell343B-Endothelial_cells-Endothelial-D|343B / Donor, Lineage, Cell class and subclass (all cells)

SELP FAM171A1 IL33 STAB1

3.51e-0419676499953fe0a40e242f6945150345fc0a08ed95f8f9
ToppCell343B-Endothelial_cells-Endothelial-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

SELP FAM171A1 IL33 STAB1

3.51e-041967645edffdc4c1ff35d9ee0e5c1bed0dc0c90b76ea00
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SELP IL33 CCDC85A STAB1

3.51e-0419676481278e696d823744267d6315c4d42799c4ea0b2c
ToppCell(5)_Fibroblasts-(5)_Fibroblast-E|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

BOC AOX1 CST3 SCRG1

3.58e-041977649b1c1d72c5a8c90d71ae31e4c198d2276872eaa0
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SELP IL33 CCDC85A STAB1

3.58e-0419776488859b7b24b36afab4a684fd7abf0e0f8e5b525c
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 PARP8 SLFN5 ADAM8

3.64e-04198764d7053a898e04478c577381085f615edaad3cdc5b
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC RAB34 AOX1 PROK1

3.64e-04198764abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SELP FAM171A1 IL33 CCDC85A

3.64e-041987646fd984da5d2c419aeb34c8cbd8a00440e2f820a5
ToppCellmild-Lymphocytic-NK_cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TES SYNE1 SLFN5 CAPN15

3.64e-04198764dce3c008757786aa6bd4a869456b76b4cbbb1d5b
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TLCD1 RAB34 CST3 SCRG1

3.64e-0419876481c4c5377d0901ee9594424f08b0e4101686c850
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

BOC GUCY1A2 PTPRS AOX1

3.64e-0419876426e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 PARP8 SLFN5 ADAM8

3.64e-04198764aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC RAB34 AOX1 PROK1

3.64e-04198764ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
DrugO-342

BOC CRYZ SYNE1 AOX1

1.70e-0627744CID000014129
Drugcopper cyanide

BOC TES SYNE1

9.21e-0613743CID000011009
Drugpyridine

BOC CRYZ SYNE1 AOX1 TNKS NLRP4 GFER

1.27e-05239747CID000001049
DrugCPD-7389

SELP CRYZ AOX1

1.79e-0516743CID000067111
Diseasecomplement factor H-related protein 4 measurement

GUCY1A2 KSR2 ZBTB41

2.27e-0449713EFO_0600091
Diseaselate-onset Alzheimers disease

SELP PTPRS KLHL36 KSR2 AOX1

7.00e-04292715EFO_1001870

Protein segments in the cluster

PeptideGeneStartEntry
DDERPHNPHKIKSCE

CWC27

151

Q6UX04
HHFLEPPKIRASCLK

FAM47DP

186

A6NHR8
RACHQAIHKLHLPEP

ASB11

301

Q8WXH4
RPHHPRAKCTEALAK

CEP72

171

Q9P209
CSKPKADPAVERHHL

C1orf94

321

Q6P1W5
APPHCAKLLTEVHAA

ADAM8

636

P78325
KPQAFQKHCERRHGP

ATXN7L2

91

Q5T6C5
PITKRIRHHPANACL

AOX1

61

Q06278
APLHLPHICSICDKK

RBM20

406

Q5T481
LPQCLRKEAALHGHK

RAB34

16

Q9BZG1
PIPKDHQVLIKVHAC

CRYZ

31

Q08257
CEAPRHKPDLNHILR

CAPN15

26

O75808
HFDIKPPLHHAKNCD

OSGEPL1

236

Q9H4B0
AIKSHKLLNRPCPAA

PARP8

356

Q8N3A8
GDPRCEHNTNLKPHK

PARP8

391

Q8N3A8
KCLKPRQHHRKLQLP

FAM171A1

331

Q5VUB5
PKNDLLHRVKPAVCS

KLHL36

241

Q8N4N3
KRVNPPAHRSCLKHP

MAP10

341

Q9P2G4
RCQLHSLDTHKPKPL

GGNBP2

161

Q9H3C7
QGLPKPHLLHAACKA

HIPK4

231

Q8NE63
CHFLHRELPKRKAPR

CFAP65

1636

Q6ZU64
HNKCTKEAPPCHLLI

KSR2

446

Q6VAB6
DHHAKECSLPPQPKK

LIN28B

136

Q6ZN17
CALPSRLHPQVAHKI

CARF

411

Q8N187
KVLAKCLDNHRPLPT

C9orf131

1061

Q5VYM1
NPNRHRLKHADDKPA

LCA5

666

Q86VQ0
NLHRKVLKLHPCLAP

POLG2

366

Q9UHN1
ALKLCEGHPNIVKLH

RPS6KA5

471

O75582
LKSHLDHPHPAVRCV

NLRP4

466

Q96MN2
TKCLLNNADLAPHHP

PTPRS

1321

Q13332
AHPCRKAPHFLRLQN

PTPRT

186

O14522
HKVAPLVRSLCAKHG

FADS2B

436

A8MWK0
RKRKHHTCPCLPNLL

PROK1

71

P58294
KEELPRHIKHKDCNP

CEP104

821

O60308
HSVELHKCEKPLPDQ

IL33

201

O95760
AKLLAHPLQRPCQSH

BABAM1

296

Q9NWV8
AVIACHLPESHPKAQ

BOC

146

Q9BWV1
RKLCNHPALVLTPQH

BTAF1

1576

O14981
QDPPAKCHTKKHNPR

EHF

191

Q9NZC4
RCKQSAKDAHVLPPA

CRAMP1

431

Q96RY5
HHKPLCKGSPEQQRH

CCDC85A

281

Q96PX6
CDKFRHPLLHIQKTP

ERP44

301

Q9BS26
QKDDGKCPLNPHSHL

SELP

801

P16109
KDELPNHNCIKHLRS

RNF41

126

Q9H4P4
KACPEHSAPIKVHHN

SLC17A5

81

Q9NRA2
LDNCPFHDQPHLKRK

CST3

106

P01034
CHPVKALDFRTPLKA

OPRK1

161

P41145
AGLHRKSLCHAKPIA

GUCY1A2

576

P33402
LKNHPSLRCHEDLPL

FAN1

641

Q9Y2M0
AKQLPAHDQDPSKCH

TES

151

Q9UGI8
SDKGPHHLCEKRLQL

SYNE1

1066

Q8NF91
VVKHLPKAHILACAP

MOV10

541

Q9HCE1
KEPHCHIPIKRNSIF

NGEF

51

Q8N5V2
TCQEPKEFRLPKDHH

NDUFAF4

86

Q9P032
CCIEPLHSKPELKDH

VPS8

296

Q8N3P4
KILKDHNCHNLPEGV

SCRG1

31

O75711
PPHHDTIKKECLACR

SARDH

551

Q9UL12
CHLHNEVNRKLGKPD

GFER

171

P55789
PLPCAIAQSRAHHAK

C10orf90

71

Q96M02
CPEPNCRVKKSLHGH

RNF31

911

Q96EP0
PAHKKHCRERKRPFQ

ZMYND19

206

Q96E35
ECHTPHKPQKRKSLE

USPL1

96

Q5W0Q7
PCHTPKKNSIHELLL

SSH2

776

Q76I76
LVHHPEAKAPCNQAI

STKLD1

401

Q8NE28
LHCAVASLHPKRKQV

TNKS

526

O95271
RLKHQEKFHLGPFPC

ZBTB41

506

Q5SVQ8
ILPILPKHCSEEQHK

STAB1

646

Q9NY15
KNPLKECLPHSHDVS

TSTD2

131

Q5T7W7
LPAHLQHDCPKRRLK

TRAF4

126

Q9BUZ4
ELHATTPLKKPNRCH

TET3

1671

O43151
LRSDFCPEHVPKKQH

TLCD1

226

Q96CP7
SCLLKHQRLHSGEKP

ZNF221

491

Q9UK13
CLLKHQRLHSGEKPL

ZNF221

576

Q9UK13
LPDHLLVHHRSCKPK

ZNF474

176

Q6S9Z5
IKEFHRKHPNEICVP

SF3A3

91

Q12874
PHPELCTVRKDLHQN

SMYD5

96

Q6GMV2
KLPVHHFCTQRPEIK

SLFN5

261

Q08AF3
LHLARPKAQSDKCVP

THEG

301

Q9P2T0
LPHCLPAHDSKQRLD

ZMAT1

466

Q5H9K5
KAHLCLEARQKHPPA

KDM5C

986

P41229