Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutamine N-acyltransferase activity

GLYATL1 GLYATL1B

4.97e-062452GO:0047946
GeneOntologyMolecularFunctionglycine N-acyltransferase activity

GLYATL1 GLYATL1B

4.94e-055452GO:0047961
GeneOntologyMolecularFunction2'-5'-oligoadenylate synthetase activity

OAS2 OAS3

4.94e-055452GO:0001730
Domain2-5-oligoadenylate_synth_CS

OAS2 OAS3

2.81e-054412IPR006117
Domain25A_SYNTH_3

OAS2 OAS3

2.81e-054412PS50152
DomainOAS1_C

OAS2 OAS3

2.81e-054412PF10421
Domain-

OAS2 OAS3

2.81e-0544121.10.1410.20
Domain25A_SYNTH_1

OAS2 OAS3

2.81e-054412PS00832
Domain25A_SYNTH_2

OAS2 OAS3

2.81e-054412PS00833
Domain2-5-oligoAdlate_synth_1_dom2/C

OAS2 OAS3

2.81e-054412IPR018952
Domain2-5A_synthase

OAS2 OAS3

2.81e-054412IPR026774
Domain2-5-oligoadenylate_synth_N

OAS2 OAS3

4.68e-055412IPR006116
DomainPH-BEACH_dom

NBEAL1 NSMAF

1.31e-048412IPR023362
DomainGlyco_trans_14

XYLT1 GCNT2

1.31e-048412IPR003406
DomainBranch

XYLT1 GCNT2

1.31e-048412PF02485
DomainPH_BEACH

NBEAL1 NSMAF

1.31e-048412PS51783
Domain-

NBEAL1 NSMAF

1.31e-0484122.30.29.40
DomainBeach

NBEAL1 NSMAF

1.68e-049412PF02138
Domain-

NBEAL1 NSMAF

1.68e-0494121.10.1540.10
DomainBEACH_dom

NBEAL1 NSMAF

1.68e-049412IPR000409
DomainBeach

NBEAL1 NSMAF

1.68e-049412SM01026
DomainBEACH

NBEAL1 NSMAF

1.68e-049412PS50197
DomainNTP_transf_2

OAS2 OAS3

2.55e-0411412PF01909
DomainPolymerase_NTP_transf_dom

OAS2 OAS3

2.55e-0411412IPR002934
DomainZnMc

ASTL MMP16

1.84e-0329412SM00235
DomainPeptidase_Metallo

ASTL MMP16

1.84e-0329412IPR006026
DomainSCAN

ZSCAN25 ZSCAN20

6.72e-0356412SM00431
DomainSCAN_BOX

ZSCAN25 ZSCAN20

7.19e-0358412PS50804
DomainSCAN

ZSCAN25 ZSCAN20

7.19e-0358412PF02023
DomainSCAN_dom

ZSCAN25 ZSCAN20

7.19e-0358412IPR003309
DomainRetrov_capsid_C

ZSCAN25 ZSCAN20

7.43e-0359412IPR008916
DomainIg_I-set

MAG HMCN1 MYBPC1

8.32e-03190413IPR013098
DomainI-set

MAG HMCN1 MYBPC1

8.32e-03190413PF07679
DomainMetalloPept_cat_dom

ASTL MMP16

1.37e-0281412IPR024079
Domain-

ASTL MMP16

1.37e-02814123.40.390.10
DomainPH_dom-like

DAB1 NBEAL1 RGS3 NSMAF

1.39e-02426414IPR011993
DomainIGc2

MAG HMCN1 MYBPC1

1.47e-02235413SM00408
DomainIg_sub2

MAG HMCN1 MYBPC1

1.47e-02235413IPR003598
Pubmed

MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization.

GSTK1 IMMT FECH

3.52e-062345322114354
Pubmed

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.

OAS2 OAS3

4.91e-06345227899133
Pubmed

Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies.

OAS2 OAS3

4.91e-0634522440675
Pubmed

OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis.

OAS2 OAS3

4.91e-06345235305973
Pubmed

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19.

OAS2 OAS3

4.91e-06345233138195
Pubmed

The human 2',5'-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40-kDa forms.

OAS2 OAS3

4.91e-0634529790745
Pubmed

Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype?

OAS2 OAS3

4.91e-06345216014697
Pubmed

Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.

OAS2 OAS3

4.91e-06345223337612
Pubmed

OAS1, OAS2 and OAS3 restrict intracellular M. tb replication and enhance cytokine secretion.

OAS2 OAS3

4.91e-06345230822544
Pubmed

Gene structure of the murine 2'-5'-oligoadenylate synthetase family.

OAS2 OAS3

9.81e-06445212222967
Pubmed

Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection.

OAS2 OAS3

9.81e-06445219923450
Pubmed

Variability in the 2'-5'-oligoadenylate synthetase gene cluster is associated with human predisposition to tick-borne encephalitis virus-induced disease.

OAS2 OAS3

9.81e-06445221050126
Pubmed

The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities.

OAS2 OAS3

1.63e-05545221142819
Pubmed

Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene family.

OAS2 OAS3

1.63e-05545212396720
Pubmed

Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2',5'-oligoadenylate synthetases.

OAS2 OAS3

2.45e-05645214559211
Pubmed

A pharmacogenetic study of polymorphisms in interferon pathway genes and response to interferon-alpha treatment in chronic hepatitis B patients.

OAS2 OAS3

4.56e-05845219559055
Pubmed

Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: A pilot study.

OAS2 OAS3

8.94e-051145212447867
Pubmed

Identification of a candidate gene for astigmatism.

XYLT1 SMPDL3B

8.94e-051145223322567
Pubmed

Positional cloning of the murine flavivirus resistance gene.

OAS2 OAS3

1.47e-041445212080145
Pubmed

Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.

OAS2 OAS3

2.76e-041945223149075
Pubmed

Translational regulation by HIV leader RNA, TAT, and interferon-inducible enzymes.

OAS2 OAS3

2.76e-04194521708818
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

BCL9L HELZ BCOR GSTK1 IMMT

3.04e-0445745532344865
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

HELZ DDX31 ZSCAN25 SENP3

1.07e-0334945425665578
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

HELZ POLD4 FAT1 SMPDL3B SPHK1 RGS3 MYBPC1

1.27e-03129345715342556
Cytoband12q24.2

OAS2 OAS3

1.12e-041645212q24.2
GeneFamilyGlucosaminyl (N-acetyl) transferases/xylosyltransferases

XYLT1 GCNT2

5.54e-058262441
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 NSMAF

7.11e-0592621230
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MAG HMCN1 MYBPC1

1.55e-03161263593
CoexpressionDOANE_RESPONSE_TO_ANDROGEN_UP

POLD4 RUNDC3A DDX31 MZB1 MYBPC1

1.44e-05185445M7600
CoexpressionGSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP

FAM171A1 OAS2 OAS3 C1orf159 GSTK1

1.90e-05196445M6293
CoexpressionGSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_DN

GSTK1 MZB1 INPPL1 ATP6V0E2 RTTN

2.05e-05199445M5281
CoexpressionGSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP

BCL9L OAS2 OAS3 CFAP126 FECH

2.10e-05200445M9489
CoexpressionGSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP

OAS2 GCNT2 RASGRP3 INPPL1 NSMAF

2.10e-05200445M7168
CoexpressionFARMER_BREAST_CANCER_CLUSTER_1

OAS2 OAS3 MZB1

7.24e-0548443M15015
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSCAN25 GCNT2 HMCN1 RGS3 GPR182 ATP6V0E2

2.06e-08172456f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSCAN25 GCNT2 HMCN1 RGS3 GPR182 ATP6V0E2

2.06e-081724566ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 RGS3 RASGRP3 GPR182 MTSS1

1.22e-061864550ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

XYLT1 FAM171A1 HMCN1 MMP16 RASGRP3

1.47e-06193455e1d546165dcc2392f540162206852c4717d7306f
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAM171A1 MMP16 SPHK1 RASGRP3 GPR182

1.66e-061984559ab0db78394e730f6866b2db80047149024ad5f6
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAM171A1 MMP16 SPHK1 RASGRP3 GPR182

1.66e-06198455e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

XYLT1 OAS2 OAS3 GCNT2

1.39e-05145454ab0e254a8d01021619853a6c175f620ccef217d8
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

XYLT1 OAS2 OAS3 GCNT2

1.39e-051454542beb4ea3838796c580076ab7769de877a3a0552c
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

OAS2 OAS3 C1orf159 ZSCAN25

2.42e-05167454820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCelldroplet-Kidney-KIDNEY-1m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 DDX31 SMPDL3B BCOR

2.66e-05171454d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFAP126 SPHK1 RASGRP3 GPR182

3.04e-05177454d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM171A1 HMCN1 RASGRP3 GPR182

3.32e-051814544df7972f88117108698efd06b124b232f8588981
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM171A1 HMCN1 RASGRP3 GPR182

3.32e-05181454cbb530566893281289026bfd93adf721decd4ca3
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 ASTL RTTN GGT7

3.46e-051834540e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 ASTL RTTN GGT7

3.46e-05183454cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB1 MAG MMP16 ATP6V0E2

3.54e-05184454da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCelldroplet-Heart-4Chambers-21m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 RGS3 RASGRP3 GPR182

3.54e-05184454f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 POLD4 MZB1 RASGRP3

3.61e-05185454bf4dbb5f139566750e50a81eb062ed8b9e5786c3
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 POLD4 MZB1 RASGRP3

3.61e-051854543d035bb453a5942411da4eb8b3a1ca0961a089b2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAB1 FAT1 GCNT2 MTSS1

3.69e-05186454310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLYATL1B MZB1 RASGRP3 MTSS1

3.77e-05187454d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

POLD4 MZB1 RASGRP3 MTSS1

3.77e-05187454160e5f338537d90d50f863a1be801b1071ac7da7
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 OAS2 OAS3 RASGRP3

3.77e-05187454dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAB1 FAT1 GCNT2 MTSS1

3.85e-05188454433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 OAS2 MMP16 RASGRP3

3.85e-05188454789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 OAS2 RASGRP3 MTSS1

3.93e-051894545d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FAM171A1 HMCN1 MMP16 RASGRP3

3.93e-05189454360f09f46231a83f99d8fa0158b72a38068e1642
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAB1 FAT1 GCNT2 MTSS1

3.93e-05189454f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLYATL1B MZB1 RASGRP3 MTSS1

4.01e-05190454112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 OAS2 RASGRP3 MTSS1

4.01e-05190454a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLD4 MZB1 RASGRP3 MTSS1

4.01e-05190454ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

MAG MMP16 RASGRP3 GPR182

4.01e-05190454bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM171A1 HMCN1 MMP16 GPR182

4.01e-051904549b0ad888eb20acc011904d8593bc32bdef18d050
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

MAG MMP16 RASGRP3 GPR182

4.01e-0519045408437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLYATL1B MZB1 RASGRP3 MTSS1

4.09e-05191454a831e30f37aff329d83fac9bdb84f783075d5df6
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAT1 MMP16 RGS3 MYBPC1

4.09e-05191454cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM171A1 HMCN1 MMP16 GPR182

4.09e-05191454fcdf3a747038e346a467eae8b7c293592658b53f
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLD4 MZB1 RASGRP3 MTSS1

4.09e-051914549502533a7946626e1714a22a0f16c70d296edf16
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAT1 MMP16 RGS3 MYBPC1

4.09e-05191454c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLYATL1B MZB1 RASGRP3 MTSS1

4.09e-051914542453064c39b359088d43d52792bf829f83442c82
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM171A1 HMCN1 MMP16 GPR182

4.18e-051924541990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM171A1 HMCN1 MMP16 GPR182

4.18e-05192454845cc9c18b4436b07dd3ce7980052683937546d2
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM171A1 HMCN1 MMP16 GPR182

4.18e-05192454c157981b9a179925edcaabc0cb3b8805f0929004
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 HMCN1 MMP16 RASGRP3

4.18e-051924540aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM171A1 HMCN1 MMP16 GPR182

4.18e-05192454c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM171A1 HMCN1 MMP16 GPR182

4.18e-05192454cd4c9b9ab17a779c154264f7459020f51e528ba5
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLYATL1B MZB1 RASGRP3 MTSS1

4.26e-051934546e6c5ae39ea880ba809019a7d39f50e4e02007ed
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GLYATL1B MZB1 RASGRP3 MTSS1

4.26e-05193454c04ac5884be4245b75d211046f04d76ae0cfb998
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 HMCN1 MMP16 RASGRP3

4.26e-051934546e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 MMP16 RASGRP3 MTSS1

4.26e-05193454aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 MMP16 RASGRP3 MTSS1

4.26e-05193454c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 HMCN1 MMP16 RASGRP3

4.35e-051944540b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM171A1 HMCN1 MMP16 GPR182

4.44e-051954540c15be3e7c238e329505dcbbe197a977d1019d45
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM171A1 HMCN1 MMP16 GPR182

4.44e-0519545445ac0fdbeb0982d798c613a6d15715d725608aa9
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM171A1 HMCN1 RASGRP3 GPR182

4.44e-0519545412ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM171A1 HMCN1 MMP16 GPR182

4.44e-051954545b1f04a745467876b09113ee17ababd3fcf9fb01
ToppCellfacs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM171A1 RASGRP3 GPR182 MTSS1

4.44e-051954543969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OAS2 OAS3 SPHK1 MTSS1

4.71e-05198454454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCellmild-B_memory|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FAT1 MZB1 RASGRP3 MTSS1

4.80e-05199454e6ac9a0959b0de2c6a99298feb7715aa80ade1dd
ToppCellCOVID-19_Severe-NK_activated|COVID-19_Severe / Disease condition and Cell class

OAS2 OAS3 RGS3 MTSS1

4.89e-05200454f1f6c7f7f75f891c9ccf6bf58f4d65b9cf10bbd8
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAB1 FAT1 GCNT2 MTSS1

4.89e-05200454d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCellNeuronal-Inhibitory-iA|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAB1 FAT1 GCNT2 MTSS1

4.89e-052004545ef4a3dc18a44292184a59ced916183c0699b01e
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAM171A1 OAS2 RGS3 GPR182

4.89e-05200454f15fffefe372005c33e31845982e2d2714ac26af
ToppCelldroplet-Fat-Mat-18m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf159 RTTN FECH

1.41e-04100453ea36e4ff513d66186b92e39c549e55c26609cb30
ToppCelldroplet-Fat-Mat-18m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1orf159 RTTN FECH

1.41e-04100453ceca7d9342e5ee7293f07edb815beee4eb010fe7
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAG FAT1 HMCN1

2.66e-0412445336dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPHK1 INPPL1 MYBPC1

2.79e-041264533539a8fdbb52d191f36dce68c38798ad4d2b491a
ToppCellcontrol-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MZB1 NBEAL1 RASGRP3

3.06e-041304539fe3c5be8488d341cff38757daf7856c112410d0
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SMPDL3B SPHK1 GPR182

3.96e-04142453671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SMPDL3B SPHK1 GPR182

3.96e-041424533557084150670fd2e2634fc674f228ab85181b59
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SMPDL3B SPHK1 GPR182

3.96e-041424536a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SMPDL3B SPHK1 GPR182

3.96e-04142453a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

CCDC187 ZSCAN20 MZB1

4.21e-04145453ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RUNDC3A MMP16 FECH

4.30e-0414645303a6a442f1f6d173a41aeebbfe41ee08853d9585
ToppCellLymphoid-Lymphoid-B_cells|Lymphoid / shred on cell class and cell subclass (v4)

POLD4 MZB1 RASGRP3

4.65e-041504535ebf6b4b9b029422a4676ba09a6a9225bd25db47
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 OAS2 GCNT2

4.65e-041504536e806a028c0519489151c181d9907e05289e27e0
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

FAM171A1 FAT1 HMCN1

4.65e-04150453b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 GCNT2 FECH

4.74e-04151453771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS3 GCNT2 FECH

4.74e-041514535893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 HMCN1 MTSS1

4.93e-041534539c6fce56300ba5053efda59a438d63a808c497c0
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

OAS2 OAS3 RASGRP3

5.21e-04156453fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCelldroplet-Thymus-nan-18m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLD4 MZB1 RASGRP3

5.31e-04157453a9e077f686382303f0437ebfa4f11d273ba9fe40
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|367C / Donor, Lineage, Cell class and subclass (all cells)

OAS2 OAS3 RASGRP3

5.41e-041584530559cc032d0b518bb9e55aa3495f5573bd8e87dd
ToppCelldroplet-Marrow-nan-21m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 ZSCAN20 MZB1

5.82e-04162453d0ffebf5adee8a3ac9b81a4b793184f54010489a
ToppCell11.5-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

RUNDC3A SPHK1 FECH

5.92e-04163453e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCellfacs-Marrow-T-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MZB1 SPHK1 FECH

5.92e-04163453c1e9c3b05d407b4dff1cd53de688b43b61128ad0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

MZB1 RASGRP3 MTSS1

5.92e-041634536bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell11.5-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

RUNDC3A SPHK1 FECH

5.92e-0416345331b60e065bac4ad380247964e7574f210106ebae
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZSCAN25 SMPDL3B GPR182

5.92e-041634533efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell343B-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SMPDL3B MZB1 RASGRP3

6.03e-04164453cf62d34ce9dd220fe61748466c84fd70d9ba697c
ToppCell343B-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SMPDL3B MZB1 RASGRP3

6.03e-04164453e00549bc8b3a5566f39031f39d7e698b0b107a7f
ToppCellcontrol-Plasmablast|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MZB1 NBEAL1 RASGRP3

6.14e-0416545361063e0ce61bc92d5d1093be8279af03f650720b
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT2 SMPDL3B HMCN1

6.25e-04166453e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT2 SMPDL3B HMCN1

6.25e-041664533ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT2 SMPDL3B HMCN1

6.25e-04166453f751cbd01d4978ded7755874ab60504f6291afd7
ToppCellCOVID-19_Severe-CD4+_T_activated|COVID-19_Severe / Disease condition and Cell class

OAS2 OAS3 MZB1

6.25e-041664530f138dbafad6f83975944e8f6398411127b150cc
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLD4 MZB1 MYBPC1

6.36e-041674534520ee71e2b119c1dfa0e342fe57eda5f3598650
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

GLYATL1 GLYATL1B RASGRP3

6.47e-04168453a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 RGS3 GPR182

6.47e-0416845306dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell367C-Lymphocytic-B_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

MZB1 RASGRP3 MTSS1

6.47e-04168453f4414d462d35abd00e3c1446302d7060f8a48d48
DrugApApA(Sp)A

OAS2 OAS3

2.18e-054442CID000501019
DrugApA(Sp)A

OAS2 OAS3

2.18e-054442CID000501015
DrugApA(Sp)ApA

OAS2 OAS3

2.18e-054442CID000501017
DrugA(Sp)ApA

OAS2 OAS3

2.18e-054442CID000501013
Drugadenosine N'-oxide

OAS2 OAS3

2.18e-054442CID000459896
Drugpoly(I,8-azidoI).poly(C

OAS2 OAS3

2.18e-054442CID003081572
DrugAztreonam [78110-38-0]; Down 200; 9.2uM; PC3; HT_HG-U133A

OAS2 C1orf159 DDX31 GCNT2 RGS3

3.54e-051944452118_DN
DrugPiracetam [7491-74-9]; Up 200; 28.2uM; HL60; HG-U133A

OAS3 DDX31 RGS3 INPPL1 SENP3

3.90e-051984451710_UP
DrugIsoxicam [34552-84-6]; Up 200; 12uM; HL60; HT_HG-U133A

RUNDC3A DDX31 RGS3 SENP3 ZNF184

3.99e-051994451862_UP
DrugMX220

OAS2 OAS3

5.45e-056442CID000514000
Diseasecataract (is_implicated_in)

GCNT2 BCOR

6.59e-0426432DOID:83 (is_implicated_in)
Diseasecytotoxicity measurement, response to clozapine

HMCN1 NSMAF

8.21e-0429432EFO_0006952, GO_0097338
Diseasepneumonia

FAM171A1 BCL9L

2.15e-0347432EFO_0003106
DiseaseCirrhosis

SPHK1 FECH

2.43e-0350432C1623038
DiseaseFibrosis

SPHK1 FECH

2.43e-0350432C0016059
DiseaseInfluenza

OAS2 OAS3

2.63e-0352432C0021400
Diseaseinformation processing speed, response to cranial radiation therapy

XYLT1 FAM171A1

3.26e-0358432EFO_0004363, EFO_0010950
Diseaseresponse to ketamine

DAB1 MMP16

4.57e-0369432EFO_0009748
Diseasebiological sex

DAB1 DDX31 MMP16

4.58e-03230433PATO_0000047
Diseasepsychotic symptoms

DAB1 RASGRP3

5.24e-0374432EFO_0005940

Protein segments in the cluster

PeptideGeneStartEntry
GAPGEWVSMQPQPLL

CCDC187

896

A0A096LP49
MGLEPPPEVWQVLKT

POLD4

76

Q9HCU8
SLPWKMGVSPGNPVD

BCOR

286

Q6W2J9
SNKWPMGGSGVVEVP

ASTL

91

Q6HA08
MAGISVPPIQKWPGS

NBEAL1

576

Q6ZS30
LVWRMVPQVKPGPDG

RGS3

371

P49796
MIGVISVEPPGIPLW

FAT1

1376

Q14517
WVAAMSPPIPGPVVT

FAM171A1

281

Q5VUB5
PWKPTVNGTMVAVEG

MAG

326

P20916
WVTLNRIPGVPGSMP

GCNT2

301

Q8N0V5
MPPPGVRLDSWKGVA

KCNQ1DN

16

Q9H478
PGVTPWKTTLPGVVN

SMPDL3B

301

Q92485
SWETKPGLLVGVPGM

GGT7

221

Q9UJ14
IGPGMFPSSQIPSWK

MTSS1

396

O43312
LGPEGVPVSWVTMDP

GLYATL1

211

Q969I3
ITPEVLPGWKGMSVS

IMMT

376

Q16891
PFTWIVPGVLMGGEK

DDX31

331

Q9H8H2
DGTGNPIPPWKVPTM

OAS2

671

P29728
GNVVMSVPLPVPWTG

HELZ

1201

P42694
VQGIPPPTVTWMKDG

HMCN1

2316

Q96RW7
PVAQVMPGAQPIAWG

DAB1

361

O75553
GEKWMGPIPPAVNAR

GSTK1

211

Q9Y2Q3
GWVASPKTAMPSPGV

BCL9L

1006

Q86UU0
LGPEGVPVSWVTMDP

GLYATL1B

211

A0A0U1RQE8
GTWQMPLKIPPARVT

CFAP126

66

Q5VTH2
VKVWSGVPAEMPGTK

NSMAF

736

Q92636
GPMPWLGPQTDESIK

FECH

306

P22830
IPVTSMLFPVPETWG

C1orf159

281

Q96HA4
MGRNGIPIQPWPVKA

OAS3

1071

Q9Y6K5
WGPIGKDPTPSMLGL

RUNDC3A

396

Q59EK9
PMPTEIIKDYTWQGP

RTTN

1446

Q86VV8
GPIMWVRPGEQMIPV

RSBN1L

516

Q6PCB5
NKPVVPLEWALGVMP

RASGRP3

396

Q8IV61
MSVKPSWGPGPSEGV

GPR182

1

O15218
VFIGTWNMGSVPPPK

INPPL1

426

O15357
MKETIQGTGSWGPEP

SENP3

1

Q9H4L4
PVGMQKWGKGPNVTV

XYLT1

766

Q86Y38
PRVPTLPKMGSVGDW

ZSCAN20

206

P17040
PITVWKGIPESPQGA

MMP16

476

P51512
GIQLGPVEVKPEWGM

ZSCAN25

151

Q6NSZ9
WFVPKGPNRGVIITM

ATP6V0E2

26

Q8NHE4
MVSGCVEPPPSWKPQ

SPHK1

361

Q9NYA1
EQGTEPWIMEPSIPV

ZNF184

81

Q99676
EIPISGEPPPKAMWS

MYBPC1

546

Q00872
GPEPSISVMVTGGPW

MZB1

121

Q8WU39