Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1S TRPV1 TRPA1 SLC39A9 GJB4 SLC6A17 ABCC11 SLC26A9 SLCO1B1 ABCA10 MFSD12 SLC22A7 SLC45A4 SLC5A2 ABCB4 SLC8A1 GSDME ATP11B SLCO4C1 SLC16A6 SLC16A4 ABCA5 KCND1 KCND2 KCND3 SLC18A1 SLC25A39 SLC22A4 SLC22A5 SCN7A SCN9A ABCD3 HRH1 SLC13A5 SLC7A5 CACNA1I XPR1

2.66e-13118015737GO:0022857
GeneOntologyMolecularFunctiontransporter activity

CACNA1S TRPV1 TRPA1 SLC39A9 GJB4 SLC6A17 ABCC11 SLC26A9 SLCO1B1 ABCA10 MFSD12 SLC22A7 SLC45A4 SLC5A2 ABCB4 SLC8A1 GSDME ATP11B SLCO4C1 SLC16A6 SLC16A4 ABCA5 KCND1 KCND2 KCND3 SLC18A1 SLC25A39 SLC22A4 SLC22A5 SCN7A SCN9A ABCD3 HRH1 SLC13A5 SLC7A5 CACNA1I ATP11A XPR1

7.87e-13128915738GO:0005215
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A17 ABCC11 SLC26A9 SLCO1B1 ABCA10 MFSD12 SLC22A7 SLC45A4 SLC5A2 ABCB4 SLC8A1 SLCO4C1 SLC16A4 ABCA5 SLC18A1 SLC22A4 SLC22A5 ABCD3 SLC13A5 SLC7A5 XPR1

1.77e-1047715721GO:0022804
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A17 SLC26A9 SLCO1B1 MFSD12 SLC22A7 SLC45A4 SLC5A2 SLC8A1 SLCO4C1 SLC16A4 SLC18A1 SLC22A4 SLC22A5 SLC13A5 SLC7A5 XPR1

1.64e-0929615716GO:0015291
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TRPV1 TRPA1 OR1B1 OR4Q2 SLC39A9 OR4C16 OR6Q1 INSR OR8K5 OR5H14 SSTR2 GABBR2 OR2T4 OR8B8 NRP1 CXCR5 PLXNC1 PTPRZ1 OR4A15 OR7D2 OR13A1 SCN7A HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1 KIT ADGRA3

1.65e-08135315732GO:0004888
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR1B1 OR4Q2 SLC39A9 OR4C16 OR6Q1 OR8K5 OR5H14 SSTR2 GABBR2 OR2T4 OR8B8 CXCR5 OR4A15 OR7D2 OR13A1 HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1 ADGRA3

1.11e-0788415724GO:0004930
GeneOntologyMolecularFunctionA-type (transient outward) potassium channel activity

KCND1 KCND2 KCND3

1.90e-0641573GO:0005250
GeneOntologyMolecularFunctionsymporter activity

SLC6A17 MFSD12 SLC45A4 SLC5A2 SLC16A4 SLC18A1 SLC22A4 SLC22A5 SLC13A5

2.94e-061501579GO:0015293
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCC11 SLC26A9 SLCO1B1 MFSD12 SLC22A7 SLCO4C1 SLC16A6 SLC16A4 SLC25A39 ABCD3 SLC13A5 SLC7A5

3.65e-0629315712GO:0008514
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1S TRPV1 TRPA1 SLC39A9 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 SLC13A5 CACNA1I

4.16e-0646515715GO:0046873
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCC11 SLC26A9 SLCO1B1 MFSD12 SLC22A7 SLC16A6 SLC16A4 ABCD3 SLC13A5 SLC7A5

5.75e-0620715710GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCC11 SLC26A9 SLCO1B1 MFSD12 SLC22A7 SLC16A6 SLC16A4 ABCD3 SLC13A5 SLC7A5

6.00e-0620815710GO:0005342
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1S TRPV1 TRPA1 SLC39A9 ABCC11 SLC26A9 SLC45A4 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 SLC13A5 CACNA1I XPR1

8.29e-0675815719GO:0015318
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC11 CHD8 MSH2 DDX55 ABCA10 DHX30 ABCB4 DHX15 ATP11B ABCA5 ENTPD1 ABCD3 ATP11A DNAH8

1.06e-0544115714GO:0016887
GeneOntologyMolecularFunctionlipid transporter activity

ABCC11 SLCO1B1 ABCA10 SLC22A7 ABCB4 ATP11B ABCA5 ABCD3 ATP11A

2.55e-051961579GO:0005319
GeneOntologyMolecularFunctionATP-dependent activity

ABCC11 CHD8 MSH2 DDX55 ABCA10 DHX30 ABCB4 DNAH1 DHX15 ATP11B ABCA5 ENTPD1 ABCD3 ATP11A DNAH8 KIF11

2.81e-0561415716GO:0140657
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1S TRPV1 TRPA1 SLC39A9 SLC45A4 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 SLC13A5 CACNA1I

3.62e-0562715716GO:0022890
GeneOntologyMolecularFunctionolfactory receptor activity

OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

3.75e-0543115713GO:0004984
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

4.07e-05491575GO:0140359
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1S TRPV1 TRPA1 SLC39A9 SLC26A9 SLC45A4 SLC5A2 SLC8A1 ATP11B KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 SLC13A5 CACNA1I

5.36e-0579315718GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1S TRPV1 TRPA1 SLC39A9 SLC45A4 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 SLC13A5 CACNA1I

7.13e-0566415716GO:0008324
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC11 SLC26A9 MFSD12 SLC16A6 SLC25A39

1.18e-04611575GO:1901682
GeneOntologyMolecularFunctiontemperature-gated ion channel activity

TRPV1 TRPA1

1.83e-0431572GO:0097603
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1S TRPV1 TRPA1 KCND1 KCND2 KCND3 CACNA1I

2.03e-041521577GO:0022843
GeneOntologyMolecularFunctionfloppase activity

ABCB4 ATP11B ATP11A

2.48e-04161573GO:0140328
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B1 SLC22A7 SLCO4C1

3.57e-04181573GO:0015347
GeneOntologyMolecularFunctionamino-acid betaine transmembrane transporter activity

SLC22A4 SLC22A5

3.65e-0441572GO:0015199
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCC11 CHD8 MSH2 RRAGB DDX55 ABCA10 DHX30 ABCB4 DHX15 ATP11B ABCA5 ENTPD1 ABCD3 ATP11A DNAH8 RAB4A

4.11e-0477515716GO:0017111
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC5A2 SLC8A1 SLC18A1 SCN7A SCN9A SLC13A5 CACNA1I

4.15e-041711577GO:0015081
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1S TRPV1 TRPA1 CACNA1I

4.64e-04461574GO:0005245
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1S TRPV1 TRPA1 KCND1 KCND2 KCND3 CACNA1I

6.02e-041821577GO:0005244
GeneOntologyMolecularFunctiontestosterone 6-beta-hydroxylase activity

CYP3A7 CYP3A43

6.05e-0451572GO:0050649
GeneOntologyMolecularFunctionosmolarity-sensing monoatomic cation channel activity

TRPA1 SCN7A

6.05e-0451572GO:1990760
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1S TRPV1 TRPA1 KCND1 KCND2 KCND3 CACNA1I

6.42e-041841577GO:0022832
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

ABCC11 SLCO1B1 SLC16A6 SLC16A4 ABCD3

7.24e-04901575GO:0008028
GeneOntologyMolecularFunctionC-C chemokine receptor activity

CXCR5 CCR8 ACKR2

7.52e-04231573GO:0016493
GeneOntologyMolecularFunctionC-C chemokine binding

CXCR5 CCR8 ACKR2

8.55e-04241573GO:0019957
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC22A4 SLC22A5

9.03e-0461572GO:0015226
GeneOntologyMolecularFunctionosmosensor activity

TRPA1 SCN7A

9.03e-0461572GO:0005034
GeneOntologyMolecularFunctionchannel activity

CACNA1S TRPV1 TRPA1 GJB4 SLC26A9 GSDME KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

9.31e-0452515712GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1S TRPV1 TRPA1 GJB4 SLC26A9 GSDME KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

9.46e-0452615712GO:0022803
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCC11 CHD8 MSH2 RRAGB DDX55 ABCA10 DHX30 ABCB4 DHX15 ATP11B ABCA5 ENTPD1 ABCD3 ATP11A DNAH8 RAB4A

9.60e-0483915716GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCC11 CHD8 MSH2 RRAGB DDX55 ABCA10 DHX30 ABCB4 DHX15 ATP11B ABCA5 ENTPD1 ABCD3 ATP11A DNAH8 RAB4A

9.73e-0484015716GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCC11 CHD8 MSH2 RRAGB DDX55 ABCA10 DHX30 ABCB4 DHX15 ATP11B ABCA5 ENTPD1 ABCD3 ATP11A DNAH8 RAB4A

9.73e-0484015716GO:0016818
GeneOntologyMolecularFunctionmetalloaminopeptidase activity

LVRN ERAP1 LNPEP

1.09e-03261573GO:0070006
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN7A SCN9A CACNA1I

1.09e-03261573GO:0005248
GeneOntologyMolecularFunctionG protein-coupled chemoattractant receptor activity

CXCR5 CCR8 ACKR2

1.09e-03261573GO:0001637
GeneOntologyMolecularFunctionchemokine receptor activity

CXCR5 CCR8 ACKR2

1.09e-03261573GO:0004950
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCND1 KCND2 KCND3

1.21e-03271573GO:0015271
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1S TRPV1 TRPA1 SLC8A1 HRH1 CACNA1I

1.25e-031511576GO:0015085
GeneOntologyMolecularFunctionphosphatidylethanolamine flippase activity

ATP11B ATP11A

1.26e-0371572GO:0090555
GeneOntologyMolecularFunctionglutathione peroxidase activity

GPX2 GPX7 MGST1

1.35e-03281573GO:0004602
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCB4 ATP11B ATP11A

1.35e-03281573GO:0140326
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1S TRPV1 TRPA1 KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

1.60e-033431579GO:0005261
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP3A7 CYP3A43

1.67e-0381572GO:0101021
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

1.71e-031091575GO:0042626
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC26A9 SLC22A7 SLC13A5

1.82e-03311573GO:0005310
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLCO1B1 SLC7A5

2.13e-0391572GO:0015349
GeneOntologyMolecularFunctionarmadillo repeat domain binding

CHD8 STRN

2.13e-0391572GO:0070016
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ATP11B ATP11A

2.13e-0391572GO:0090556
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC25A39 SLC22A4 SLC22A5

2.19e-03331573GO:0072349
GeneOntologyMolecularFunctionchemokine binding

CXCR5 CCR8 ACKR2

2.19e-03331573GO:0019956
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC11 SLC18A1 SLC22A5

2.39e-03341573GO:0042910
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC11 SLCO1B1 SLC22A7 ABCD3

2.63e-03731574GO:0170055
GeneOntologyMolecularFunctionguanylate cyclase activity

GUCY2F GUCY2D

2.65e-03101572GO:0004383
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP3A7 CYP3A43

3.22e-03111572GO:0101020
GeneOntologyMolecularFunctionodorant binding

OR8K5 OR5H14 OR8B8 OR13A1 OR8B12

3.32e-031271575GO:0005549
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1S TRPV1 TRPA1 SLC26A9 KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

3.48e-0345915710GO:0005216
GeneOntologyMolecularFunctionsemaphorin receptor activity

NRP1 PLXNC1

3.85e-03121572GO:0017154
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

MFSD12 SLC22A4 SLC22A5 SLC7A5

4.18e-03831574GO:0015101
GeneOntologyMolecularFunctionaminopeptidase activity

LVRN ERAP1 LNPEP

4.67e-03431573GO:0004177
GeneOntologyMolecularFunctiongated channel activity

CACNA1S TRPV1 TRPA1 KCND1 KCND2 KCND3 SCN7A CACNA1I

5.01e-033341578GO:0022836
GeneOntologyMolecularFunctionpeptide receptor activity

SSTR2 GUCY2F GUCY2D TACR1 RXFP1

5.02e-031401575GO:0001653
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B1 SLC22A7

5.25e-03141572GO:0015132
GeneOntologyMolecularFunctionretinoic acid 4-hydroxylase activity

CYP3A7 CYP3A43

5.25e-03141572GO:0008401
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1S CACNA1I

5.25e-03141572GO:0008331
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP11B ATP11A

5.25e-03141572GO:0140333
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC22A4 SLC22A5

6.03e-03151572GO:0015651
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO1B1 SLC22A7

6.03e-03151572GO:0071714
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

TRPV1 TRPA1 OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 GUCY2F OR4A15 OR7D2 OR13A1 SCN9A PCDH15 OR2D3 OR8B12 KIT

9.14e-0858215619GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

TRPV1 TRPA1 OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 GUCY2F OR4A15 OR7D2 GUCY2D OR13A1 SCN9A PCDH15 OR2D3 OR8B12 TACR1 KIT

1.28e-0772215621GO:0051606
GeneOntologyBiologicalProcessorganic anion transport

TRPV1 SLC6A17 ABCC11 SLC26A9 SLCO1B1 MFSD12 SLC22A7 ABCB4 NF1 SLCO4C1 SLC16A6 MGST1 SLC16A4 SLC25A39 ABCD3 SLC13A5 SLC7A5

3.91e-0751515617GO:0015711
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR1B1 OR4Q2 SLC39A9 OR4C16 OR6Q1 INSR OR8K5 OR5H14 SSTR2 GABBR2 OR2T4 OR8B8 CXCR5 GUCY2F OR4A15 OR7D2 GUCY2D ENTPD1 OR13A1 HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1 ADGRA3

1.86e-06139515628GO:0007186
GeneOntologyBiologicalProcesscarboxylic acid transport

TRPV1 SLC6A17 ABCC11 SLC26A9 SLCO1B1 MFSD12 SLC22A7 ABCB4 NF1 SLC16A6 SLC16A4 ABCD3 SLC13A5 SLC7A5

2.96e-0641015614GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

TRPV1 SLC6A17 ABCC11 SLC26A9 SLCO1B1 MFSD12 SLC22A7 ABCB4 NF1 SLC16A6 SLC16A4 ABCD3 SLC13A5 SLC7A5

3.13e-0641215614GO:0015849
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

TRPV1 TRPA1 OR1B1 OR4Q2 OR4C16 GJB4 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

4.17e-0654715616GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

TRPV1 TRPA1 OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

4.34e-0648515615GO:0050907
GeneOntologyBiologicalProcesssensory perception

TRPV1 TRPA1 OR1B1 OR4Q2 OR4C16 GJB4 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 GSDME KCND2 GUCY2F OR4A15 OR7D2 GUCY2D OR13A1 SCN9A PCDH15 OR2D3 OR8B12 KIT

5.97e-06107215623GO:0007600
GeneOntologyBiologicalProcessxenobiotic transport

ABCC11 ABCB4 SLC18A1 SLC22A4 SLC22A5 SLC7A5

8.87e-06641566GO:0042908
GeneOntologyBiologicalProcesssulfur compound transport

SLC26A9 MFSD12 SLC16A6 MGST1 SLC25A39 SLC7A5

9.72e-06651566GO:0072348
GeneOntologyBiologicalProcessdetection of chemical stimulus

TRPV1 TRPA1 OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

1.09e-0552415615GO:0009593
GeneOntologyBiologicalProcesssensory perception of smell

OR1B1 OR4Q2 OR4C16 GJB4 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

1.24e-0546515614GO:0007608
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1S TRPV1 TRPA1 SLC39A9 SLC6A17 ABCC11 SLC26A9 SLCO1B1 SLC22A7 SLC5A2 SLC8A1 ATP11B SLCO4C1 KCND1 KCND2 KCND3 SLC18A1 SLC22A4 SLC22A5 SCN7A SCN9A HRH1 CD63 SLC13A5 CACNA1I GSTO1

1.30e-05137415626GO:0006811
GeneOntologyBiologicalProcessaction potential

TRPA1 SLC8A1 KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I TACR1

2.30e-052011569GO:0001508
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

2.58e-0543215613GO:0050911
GeneOntologyBiologicalProcessresponse to pain

TRPV1 TRPA1 THBS4 SCN9A TACR1

4.12e-05511565GO:0048265
GeneOntologyBiologicalProcessmulticellular organismal response to stress

TRPV1 TRPA1 HDAC5 THBS4 PDE8B SCN9A TACR1

4.92e-051261567GO:0033555
GeneOntologyBiologicalProcessmuscle contraction

CACNA1S TRPV1 TRPA1 SSTR2 SLC8A1 KCND2 KCND3 SCN7A SCN9A TACR1 GSTO1 KIT

5.49e-0540015612GO:0006936
GeneOntologyBiologicalProcessdetection of abiotic stimulus

TRPV1 TRPA1 GUCY2F GUCY2D SCN9A PCDH15 TACR1 KIT

5.71e-051751568GO:0009582
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1S TRPV1 TRPA1 SLC39A9 SLC6A17 SLC26A9 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 CD63 SLC13A5 CACNA1I GSTO1 XPR1

8.61e-05101715620GO:0098660
GeneOntologyBiologicalProcessurinary bladder smooth muscle contraction

TRPV1 TRPA1 TACR1

8.88e-05121563GO:0014832
GeneOntologyBiologicalProcessbehavioral response to pain

TRPV1 THBS4 SCN9A TACR1

9.60e-05321564GO:0048266
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1S TRPV1 TRPA1 SLC39A9 SLC6A17 ABCC11 SLC26A9 SLC5A2 SLC8A1 ATP11B KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 CD63 SLC13A5 CACNA1I GSTO1

1.04e-04111515621GO:0034220
GeneOntologyBiologicalProcesssteroid metabolic process

CYP3A7 CYP3A43 CYP51A1 SULT1A1 ABCA5 PDE8B DHCR7 ABCD3 HRH1 PLEKHA1 KIT

1.41e-0437615611GO:0008202
GeneOntologyBiologicalProcesscirculatory system process

TRPV1 TRPA1 ERAP1 SLC6A17 INSR SLC8A1 KCND2 KCND3 LNPEP SLC22A5 SCN7A SCN9A HRH1 SLC7A5 TACR1 GSTO1

1.43e-0473315616GO:0003013
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of pain

TRPV1 TRPA1

1.70e-0431562GO:0050968
GeneOntologyBiologicalProcessurinary tract smooth muscle contraction

TRPV1 TRPA1 TACR1

1.81e-04151563GO:0014848
GeneOntologyBiologicalProcessmetal ion transport

CACNA1S TRPV1 TRPA1 SLC39A9 SLC6A17 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC22A4 SLC22A5 SCN7A SCN9A HRH1 CD63 SLC13A5 CACNA1I GSTO1

2.04e-04100015619GO:0030001
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1S TRPV1 TRPA1 SLC39A9 SLC6A17 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 CD63 SLC13A5 CACNA1I GSTO1

2.18e-0492215618GO:0098662
GeneOntologyBiologicalProcesssodium ion transport

SLC6A17 SLC5A2 SLC8A1 SLC22A4 SLC22A5 SCN7A SCN9A SLC13A5 CACNA1I

2.53e-042751569GO:0006814
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1S TRPV1 TRPA1 SLC39A9 SLC6A17 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SCN7A SCN9A HRH1 CD63 SLC13A5 CACNA1I GSTO1

2.82e-0494215618GO:0098655
GeneOntologyBiologicalProcesscyclic purine nucleotide metabolic process

PDE8A GUCY2F PDE8B GUCY2D

3.38e-04441564GO:0052652
GeneOntologyBiologicalProcessmodified amino acid transport

MGST1 SLC25A39 SLC22A4 SLC22A5

3.38e-04441564GO:0072337
GeneOntologyBiologicalProcessdetection of external stimulus

TRPV1 TRPA1 GUCY2F GUCY2D SCN9A PCDH15 KIT

3.53e-041731567GO:0009581
GeneOntologyBiologicalProcesscyclic nucleotide metabolic process

PDE8A GUCY2F PDE8B GUCY2D

3.69e-04451564GO:0009187
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1S TRPV1 SLC5A2 SLC8A1 KCND3 SLC22A4 SLC7A5 CACNA1I

3.73e-042301568GO:0098739
GeneOntologyBiologicalProcessbehavior

TRPV1 GJB4 INSR CHD8 STRN THBS4 NF1 KCND2 PTPRZ1 PDE8B SLC22A5 VPS13A SCN9A PCDH15 HRH1 TACR1 KIT

4.27e-0489115617GO:0007610
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1S TRPV1 TRPA1 SLC39A9 SLC6A17 SLC5A2 SLC8A1 KCND1 KCND2 KCND3 SLC18A1 SLC22A4 SLC22A5 SCN7A SCN9A HRH1 CD63 SLC13A5 CACNA1I GSTO1

4.69e-04115715620GO:0006812
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1S TRPV1 SLC8A1 CACNA1I

4.73e-04481564GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1S TRPV1 SLC8A1 CACNA1I

4.73e-04481564GO:1902656
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SLC8A1 KCND2 KCND3 SCN7A SCN9A

5.21e-04871565GO:0086001
GeneOntologyBiologicalProcesssmooth muscle contraction

TRPV1 TRPA1 SSTR2 SLC8A1 TACR1 KIT

5.29e-041331566GO:0006939
GeneOntologyBiologicalProcessoperant conditioning

PDE8B TACR1

5.60e-0451562GO:0035106
GeneOntologyBiologicalProcesssmooth muscle contraction involved in micturition

TRPV1 TACR1

5.60e-0451562GO:0060083
GeneOntologyBiologicalProcessestrogen metabolic process

CYP3A7 CYP3A43 SULT1A1 PLEKHA1

6.43e-04521564GO:0008210
GeneOntologyBiologicalProcesspeptide catabolic process

LVRN ERAP1 LNPEP

6.73e-04231563GO:0043171
GeneOntologyBiologicalProcessoligopeptide transport

SLCO1B1 MGST1 SLC25A39

6.73e-04231563GO:0006857
GeneOntologyBiologicalProcessxenobiotic metabolic process

CYP3A7 CYP3A43 SLCO1B1 SLC22A7 SULT1A1 GSTO1

7.20e-041411566GO:0006805
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1S TRPV1 SLC5A2 SLC8A1 KCND3 CACNA1I

7.47e-041421566GO:0098659
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1S TRPV1 SLC5A2 SLC8A1 KCND3 CACNA1I

7.47e-041421566GO:0099587
GeneOntologyCellularComponentvacuolar membrane

GPR155 ABCC11 RRAGB MFSD12 ATP11B SLCO4C1 MGST1 ABCA5 LNPEP VPS13A CD63 SLC7A5 ATP11A

1.22e-0450715713GO:0005774
GeneOntologyCellularComponentlysosomal membrane

GPR155 RRAGB MFSD12 ATP11B SLCO4C1 MGST1 ABCA5 LNPEP VPS13A CD63 SLC7A5 ATP11A

1.99e-0446215712GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

GPR155 RRAGB MFSD12 ATP11B SLCO4C1 MGST1 ABCA5 LNPEP VPS13A CD63 SLC7A5 ATP11A

1.99e-0446215712GO:0098852
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN7A SCN9A CACNA1I

2.62e-04171573GO:0001518
GeneOntologyCellularComponentbasal plasma membrane

SLCO1B1 SLC22A7 SLC8A1 SLCO4C1 SLC16A6 SLC22A4 SLC22A5 ENTPD1 SLC13A5 SLC7A5

3.54e-0435415710GO:0009925
GeneOntologyCellularComponentdendritic spine

CACNA1S TRPV1 STRN SLC8A1 KCND1 KCND2 KCND3 PTPRZ1

5.00e-042421578GO:0043197
GeneOntologyCellularComponentneuron spine

CACNA1S TRPV1 STRN SLC8A1 KCND1 KCND2 KCND3 PTPRZ1

5.72e-042471578GO:0044309
GeneOntologyCellularComponentbasal part of cell

SLCO1B1 SLC22A7 SLC8A1 SLCO4C1 SLC16A6 SLC22A4 SLC22A5 ENTPD1 SLC13A5 SLC7A5

5.91e-0437815710GO:0045178
GeneOntologyCellularComponentbasolateral plasma membrane

SLCO1B1 SLC22A7 SLC8A1 SLCO4C1 SLC16A6 SLC22A5 ENTPD1 SLC13A5 SLC7A5

7.21e-043201579GO:0016323
GeneOntologyCellularComponentaxonemal dynein complex

NME8 DNAH1 DNAH8

8.47e-04251573GO:0005858
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

CYP3A7 COPZ2 ERAP1 CYP3A43 FA2H CAMLG CYP51A1 SPTLC1 SLC26A9 SEC22B MYRFL ERN2 LCLAT1 TRAM1L1 MGST1 GUCY2F SLC18A1 DHCR7 GUCY2D VPS13A ATP11A

9.65e-04132715721GO:0042175
GeneOntologyCellularComponentazurophil granule membrane

ATP11B SLCO4C1 MGST1 CD63

1.01e-03591574GO:0035577
GeneOntologyCellularComponentsodium channel complex

SCN7A SCN9A CACNA1I

1.32e-03291573GO:0034706
GeneOntologyCellularComponentendoplasmic reticulum membrane

CYP3A7 COPZ2 ERAP1 CYP3A43 FA2H CAMLG CYP51A1 SPTLC1 SLC26A9 SEC22B MYRFL ERN2 LCLAT1 TRAM1L1 MGST1 SLC18A1 DHCR7 GUCY2D VPS13A ATP11A

1.68e-03129315720GO:0005789
GeneOntologyCellularComponentcell body

TRPV1 TBX21 INSR CRMP1 NRP1 STRN SLC8A1 KCND1 KCND2 KCND3 PTPRZ1 LNPEP ENTPD1 VPS13A TACR1 GSTO1

1.72e-0392915716GO:0044297
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

CYP3A7 COPZ2 ERAP1 CYP3A43 FA2H CAMLG CYP51A1 SPTLC1 SLC26A9 SEC22B MYRFL ERN2 LCLAT1 TRAM1L1 MGST1 SLC18A1 DHCR7 GUCY2D VPS13A ATP11A

1.78e-03129915720GO:0098827
GeneOntologyCellularComponentexternal side of plasma membrane

TRPV1 STAB2 INSR CXCR5 ENTPD1 PKHD1 SLC7A5 CCR8 ACKR2 KIT ADGRA3

1.92e-0351915711GO:0009897
GeneOntologyCellularComponentcation channel complex

CACNA1S KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

2.03e-032351577GO:0034703
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1S TRPV1 FAT3 TBX21 INSR CRMP1 NRP1 STRN SLC8A1 NF1 KCND1 KCND2 KCND3 PTPRZ1 LNPEP ENTPD1 VPS13A HRH1 TACR1

2.20e-03122815719GO:0036477
DomainMFS_dom

SLCO1B1 MFSD12 SLC22A7 SLC45A4 SLCO4C1 SLC16A6 SLC16A4 SLC18A1 SLC22A4 SLC22A5

1.97e-0713415710IPR020846
DomainMFS

SLCO1B1 MFSD12 SLC22A7 SLCO4C1 SLC16A6 SLC16A4 SLC18A1 SLC22A4 SLC22A5

3.20e-071081579PS50850
DomainChannel_four-helix_dom

CACNA1S KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

4.82e-07571577IPR027359
Domain-

CACNA1S KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

4.82e-075715771.20.120.350
DomainIon_trans_dom

CACNA1S TRPV1 TRPA1 KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

5.09e-071141579IPR005821
DomainIon_trans

CACNA1S TRPV1 TRPA1 KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

5.09e-071141579PF00520
DomainShal-type_N

KCND1 KCND2 KCND3

5.83e-0731573IPR021645
DomainK_chnl_volt-dep_Kv4_C

KCND1 KCND2 KCND3

5.83e-0731573IPR024587
DomainDUF3399

KCND1 KCND2 KCND3

5.83e-0731573PF11879
DomainK_chnl_volt-dep_Kv4

KCND1 KCND2 KCND3

5.83e-0731573IPR003975
DomainShal-type

KCND1 KCND2 KCND3

5.83e-0731573PF11601
DomainGPCR_Rhodpsn_7TM

OR1B1 OR4C16 OR6Q1 OR8K5 OR5H14 SSTR2 OR2T4 OR8B8 CXCR5 OR4A15 OR7D2 OR13A1 HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1

9.04e-0767015720IPR017452
Domain7tm_1

OR1B1 OR4C16 OR6Q1 OR8K5 OR5H14 SSTR2 OR2T4 OR8B8 CXCR5 OR4A15 OR7D2 OR13A1 HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1

1.06e-0667715720PF00001
DomainG_PROTEIN_RECEP_F1_1

OR1B1 OR4C16 OR6Q1 OR8K5 OR5H14 SSTR2 OR2T4 OR8B8 CXCR5 OR4A15 OR7D2 OR13A1 HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1

1.27e-0668515720PS00237
DomainG_PROTEIN_RECEP_F1_2

OR1B1 OR4C16 OR6Q1 OR8K5 OR5H14 SSTR2 OR2T4 OR8B8 CXCR5 OR4A15 OR7D2 OR13A1 HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1

1.45e-0669115720PS50262
DomainGPCR_Rhodpsn

OR1B1 OR4C16 OR6Q1 OR8K5 OR5H14 SSTR2 OR2T4 OR8B8 CXCR5 OR4A15 OR7D2 OR13A1 HRH1 OR2D3 OR8B12 TAAR1 TACR1 CCR8 ACKR2 RXFP1

1.49e-0669215720IPR000276
DomainABC_transporter_CS

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

2.61e-05421575IPR017871
DomainERAP1-like_C_dom

LVRN ERAP1 LNPEP

3.16e-0581573IPR024571
DomainERAP1_C

LVRN ERAP1 LNPEP

3.16e-0581573PF11838
DomainMFS_1

MFSD12 SLC22A7 SLC16A6 SLC16A4 SLC18A1 SLC22A4

4.65e-05771576PF07690
DomainMFS

MFSD12 SLC22A7 SLC16A6 SLC16A4 SLC18A1 SLC22A4

4.65e-05771576IPR011701
DomainOrgcat_transp/SVOP

SLC22A7 SLC22A4 SLC22A5

4.72e-0591573IPR004749
DomainABC_tran

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

5.04e-05481575PF00005
DomainABC_TRANSPORTER_2

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

5.04e-05481575PS50893
DomainPAS

PDE8A SIM2 CLOCK PDE8B

5.30e-05251574PF00989
DomainPAS_fold

PDE8A SIM2 CLOCK PDE8B

5.30e-05251574IPR013767
DomainABC_TRANSPORTER_1

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

5.57e-05491575PS00211
DomainABC_transporter-like

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

6.15e-05501575IPR003439
DomainPDEase_PDE8

PDE8A PDE8B

7.02e-0521572IPR013938
DomainPeptidase_M1

LVRN ERAP1 LNPEP

1.21e-04121573IPR001930
DomainOlfact_rcpt

OR1B1 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

1.25e-0439315712IPR000725
DomainPAS

PDE8A SIM2 CLOCK PDE8B

1.44e-04321574SM00091
DomainPeptidase_M1_N

LVRN ERAP1 LNPEP

1.57e-04131573IPR014782
DomainPeptidase_M1

LVRN ERAP1 LNPEP

1.57e-04131573PF01433
DomainPAS

PDE8A SIM2 CLOCK PDE8B

1.83e-04341574PS50112
DomainPAS

PDE8A SIM2 CLOCK PDE8B

1.83e-04341574IPR000014
DomainAAA

ABCC11 ABCA10 ABCB4 DHX15 ABCA5 ABCD3 DNAH8

2.18e-041441577SM00382
DomainAAA+_ATPase

ABCC11 ABCA10 ABCB4 DHX15 ABCA5 ABCD3 DNAH8

2.18e-041441577IPR003593
Domain-

ABCC11 CHD8 MSH2 RRAGB DDX55 ABCA10 DHX30 ABCB4 DNAH1 DHX15 GIMAP8 SULT1A1 ABCA5 ABCD3 DNAH8 RAB4A

5.58e-04746157163.40.50.300
DomainCyt_P450_E_grp-II

CYP3A7 CYP3A43

6.91e-0451572IPR002402
DomainP-loop_NTPase

ABCC11 CHD8 MSH2 RRAGB DDX55 ABCA10 DHX30 ABCB4 DNAH1 DHX15 GIMAP8 SULT1A1 ABCA5 ABCD3 DNAH8 RAB4A KIF11

7.98e-0484815717IPR027417
DomainCyt_P450_E_CYP3A

CYP3A7 CYP3A43

1.03e-0361572IPR008072
DomainHNOB_dom_associated

GUCY2F GUCY2D

1.03e-0361572IPR011645
DomainHNOBA

GUCY2F GUCY2D

1.03e-0361572PF07701
DomainPAC

PDE8A SIM2 CLOCK

1.31e-03261573PS50113
DomainGPX_AS

GPX2 GPX7

1.43e-0371572IPR029759
DomainK_chnl_volt-dep_Kv

KCND1 KCND2 KCND3

1.47e-03271573IPR003968
DomainABC_TM1F

ABCC11 ABCB4 ABCD3

1.64e-03281573PS50929
DomainABC1_TM_dom

ABCC11 ABCB4 ABCD3

1.64e-03281573IPR011527
DomainGLUTATHIONE_PEROXID_2

GPX2 GPX7

1.90e-0381572PS00763
DomainNuc_translocat

SIM2 CLOCK

1.90e-0381572IPR001067
DomainGLUTATHIONE_PEROXID_1

GPX2 GPX7

1.90e-0381572PS00460
DomainGlutathione_peroxidase

GPX2 GPX7

1.90e-0381572IPR000889
DomainGLUTATHIONE_PEROXID_3

GPX2 GPX7

1.90e-0381572PS51355
DomainGPX_CS

GPX2 GPX7

1.90e-0381572IPR029760
DomainGSHPx

GPX2 GPX7

1.90e-0381572PF00255
DomainVG_K_chnl

KCND1 KCND2 KCND3

2.64e-03331573IPR028325
DomainNa_channel_asu

SCN7A SCN9A

3.02e-03101572IPR001696
DomainNa_trans_assoc

SCN7A SCN9A

3.02e-03101572IPR010526
DomainNa_trans_assoc

SCN7A SCN9A

3.02e-03101572PF06512
DomainVDCCAlpha1

CACNA1S CACNA1I

3.02e-03101572IPR002077
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPV1 TRPA1 ABCC11 SLC26A9 SLCO1B1 ABCA10 SLC22A7 SLC5A2 ABCB4 SLC8A1 ATP11B SLCO4C1 ABCA5 SLC18A1 SLC22A4 SLC22A5 ABCD3 SLC13A5 SLC7A5 ATP11A

1.01e-0573612820M27287
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A9 SLCO1B1 SLC22A7 SLC5A2 SLC8A1 SLCO4C1 SLC18A1 SLC22A4 SLC22A5 SLC13A5 SLC7A5

1.08e-0523812811MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A9 SLCO1B1 SLC22A7 SLC5A2 SLC8A1 SLCO4C1 SLC18A1 SLC22A4 SLC22A5 SLC13A5 SLC7A5

1.65e-0524912811M5988
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND1 KCND2 KCND3

2.49e-0571283M27457
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND1 KCND2 KCND3

2.49e-0571283MM15199
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPV1 TRPA1 SLC26A9 SLCO1B1 SLC22A7 SLC5A2 ABCB4 SLC8A1 ATP11B SLCO4C1 ABCA5 SLC18A1 SLC22A4 SLC22A5 ABCD3 SLC13A5 SLC7A5 ATP11A

4.25e-0568112818MM14985
PathwayKEGG_ABC_TRANSPORTERS

ABCC11 ABCA10 ABCB4 ABCA5 ABCD3

4.67e-05441285M11911
PathwayREACTOME_SENSORY_PERCEPTION

OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 GUCY2F OR4A15 OR7D2 GUCY2D OR13A1 SCN9A PCDH15 OR2D3 OR8B12

6.16e-0563612817M41834
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

1.07e-0441712813M4072
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A7 SLC22A4 SLC22A5

1.52e-04121283MM15192
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR1B1 OR4C16 OR6Q1 OR8K5 OR2T4 OR8B8 OR4A15 OR7D2 GUCY2D OR13A1 OR2D3 OR8B12

2.19e-0438912812M14091
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

SSTR2 OR8B8 CXCR5 HRH1 OR2D3 OR8B12 CCR8 ACKR2

2.93e-041861288MM15994
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A7 SLC22A4 SLC22A5

3.07e-04151283M888
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA10 ABCA5 ABCD3

5.40e-04181283M524
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

CYP3A7 SLC39A9 SLC6A17 GPX2 SLCO1B1 SLC5A2 ABCB4 SULT1A1 MGST1 SLC7A5

5.81e-0431412810M39428
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A7 SLC18A1 SLC22A4 SLC22A5 SLC13A5

6.30e-04761285MM15072
PathwayWP_GPCRS_NONODORANT

SSTR2 GABBR2 CXCR5 HRH1 TAAR1 TACR1 CCR8 ACKR2 RXFP1

7.15e-042661289MM15843
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

CYP3A7 CYP3A43 SLCO1B1 SLC22A7 ABCB4 SULT1A1 MGST1 ABCA5 SLC22A5 ABCD3

2.15e-081931581019343046
Pubmed

Unique clustering of A-type potassium channels on different cell types of the main olfactory bulb.

KCND1 KCND2 KCND3

9.20e-083158318371079
Pubmed

The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes.

TRPV1 TRPA1 SCN9A

9.20e-083158331285762
Pubmed

Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).

KCND1 KCND2 KCND3

9.20e-083158310729221
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

CAMLG TMEM51 INSR CYP51A1 SEC22B GPR107 NF1 LNPEP DHCR7 ABCD3 SLC7A5 CUX1 XPR1

2.48e-074671581330194290
Pubmed

Mechanisms of Broad-Band UVB Irradiation‒Induced Itch in Mice.

TRPV1 TRPA1 KIT

3.67e-074158333812858
Pubmed

Transport of gabapentin by LAT1 (SLC7A5).

SLC22A4 SLC22A5 SLC7A5

3.67e-074158323567998
Pubmed

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.

SLCO1B1 SLC22A7 SLC22A4 SLC22A5

7.15e-0716158435307651
Pubmed

The human olfactory receptor gene family.

OR1B1 OR4Q2 OR4C16 OR6Q1 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR7D2 OR13A1 OR2D3 OR8B12

1.29e-065411581314983052
Pubmed

A basophil-neuronal axis promotes itch.

TRPV1 TRPA1 KIT

1.82e-066158333450207
Pubmed

The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.

LVRN ERAP1 LNPEP SLC22A5

2.31e-0621158419578876
Pubmed

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch.

TRPV1 TRPA1 KIT

3.18e-067158332268102
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1S SLC8A1 KCND1 KCND2 KCND3 SCN7A SCN9A

3.61e-06139158716985003
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR1B1 OR4C16 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR13A1 OR2D3 OR8B12

3.89e-063401581011875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR1B1 OR4C16 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR13A1 OR2D3 OR8B12

3.89e-063401581011802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR1B1 OR4C16 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR13A1 OR2D3 OR8B12

4.20e-063431581032295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR1B1 OR4C16 OR8K5 OR5H14 OR2T4 OR8B8 OR4A15 OR13A1 OR2D3 OR8B12

4.54e-063461581014611657
Pubmed

Diverse Targets of β-Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse.

ABCC11 ABCA5 ABCD3

7.57e-069158326122848
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCC11 ABCA10 ABCA5

1.08e-0510158311435397
Pubmed

DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.

NRP1 CXCR5 ENTPD1 CCR8

1.51e-0533158427760760
Pubmed

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.

INSR SLC5A2

2.05e-052158230635569
Pubmed

Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene.

SLC22A4 SLC22A5

2.05e-052158221695374
Pubmed

cAMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis.

PDE8A PDE8B

2.05e-052158222232524
Pubmed

Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.

SLC22A4 SLC22A5

2.05e-052158216469794
Pubmed

The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors.

TRPV1 TRPA1

2.05e-052158220826794
Pubmed

TRP-channel-specific cutaneous eicosanoid release patterns.

TRPV1 TRPA1

2.05e-052158221962912
Pubmed

Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx.

TRPV1 TRPA1

2.05e-052158226472811
Pubmed

Pronociceptive response elicited by TRPA1 receptor activation in mice.

TRPV1 TRPA1

2.05e-052158218272293
Pubmed

Gene expression of carnitine organic cation transporters 1 and 2 (OCTN) is downregulated in patients with ulcerative colitis.

SLC22A4 SLC22A5

2.05e-052158221910182
Pubmed

Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan.

SLC22A4 SLC22A5

2.05e-052158218274826
Pubmed

TRPV1 and TRPA1 channels interact to mediate cold hyperalgesia in mice.

TRPV1 TRPA1

2.05e-052158237690945
Pubmed

TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch.

TRPV1 TRPA1

2.05e-052158234439832
Pubmed

Striatal TRPV1 activation by acetaminophen ameliorates dopamine D2 receptor antagonist-induced orofacial dyskinesia.

TRPV1 TRPA1

2.05e-052158233857021
Pubmed

Ammonium chloride-induced hypothermia is attenuated by transient receptor potential channel vanilloid-1, but augmented by ankyrin-1 in rodents.

TRPV1 TRPA1

2.05e-052158238615746
Pubmed

Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids.

SLC22A4 SLC22A5

2.05e-052158219814996
Pubmed

Long-term c-Kit overexpression in beta cells compromises their function in ageing mice.

INSR KIT

2.05e-052158231154478
Pubmed

Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.

GUCY2F GUCY2D

2.05e-05215827777544
Pubmed

The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis.

ABCB4 ENTPD1

2.05e-052158229404503
Pubmed

Resolvin D5 Inhibits Neuropathic and Inflammatory Pain in Male But Not Female Mice: Distinct Actions of D-Series Resolvins in Chemotherapy-Induced Peripheral Neuropathy.

TRPV1 TRPA1

2.05e-052158231333464
Pubmed

The high-affinity cAMP-specific phosphodiesterase 8B controls steroidogenesis in the mouse adrenal gland.

PDE8A PDE8B

2.05e-052158221187369
Pubmed

Characterization of Transient Receptor Potential Vanilloid-1 (TRPV1) Variant Activation by Coal Fly Ash Particles and Associations with Altered Transient Receptor Potential Ankyrin-1 (TRPA1) Expression and Asthma.

TRPV1 TRPA1

2.05e-052158227758864
Pubmed

TRPA1 Mediates Aromatase Inhibitor-Evoked Pain by the Aromatase Substrate Androstenedione.

TRPV1 TRPA1

2.05e-052158227758889
Pubmed

TRPV1, but not TRPA1, in primary sensory neurons contributes to cutaneous incision-mediated hypersensitivity.

TRPV1 TRPA1

2.05e-052158223497345
Pubmed

Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1.

TRPV1 TRPA1

2.05e-052158228176353
Pubmed

Localization and expression of TRPV1 and TRPA1 in the human oropharynx and larynx.

TRPV1 TRPA1

2.05e-052158226530852
Pubmed

The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia.

SLC7A5 TAAR1

2.05e-052158217212650
Pubmed

Lack of neurokinin-1 receptor expression affects tissue mast cell numbers but not their spatial relationship with nerves.

TACR1 KIT

2.05e-052158215458971
Pubmed

[Activation and regulation of nociceptive transient receptor potential (TRP) channels, TRPV1 and TRPA1].

TRPV1 TRPA1

2.05e-052158220190512
Pubmed

Glutathione peroxidase-2 protects from allergen-induced airway inflammation in mice.

GPX2 GSTO1

2.05e-052158219897562
Pubmed

Reanalysis of ATP11B, a type IV P-type ATPase.

ATP11B ATP11A

2.05e-052158211790799
Pubmed

Lysophosphatidic acid activates satellite glia cells and Schwann cells.

TRPV1 TRPA1

2.05e-052158230637823
Pubmed

Psoralens activate and photosensitize Transient Receptor Potential channels Ankyrin type 1 (TRPA1) and Vanilloid type 1 (TRPV1).

TRPV1 TRPA1

2.05e-052158232862473
Pubmed

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.

SLC22A4 SLC22A5

2.05e-052158221606177
Pubmed

Reactive dicarbonyl compounds cause Calcitonin Gene-Related Peptide release and synergize with inflammatory conditions in mouse skin and peritoneum.

TRPV1 TRPA1

2.05e-052158232198181
Pubmed

Differential contribution of sensory transient receptor potential channels in response to the bioactive lipid sphingosine-1-phosphate.

TRPV1 TRPA1

2.05e-052158232089077
Pubmed

Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.

SLC22A4 SLC22A5

2.05e-052158220020740
Pubmed

Reactive metabolites of acetaminophen activate and sensitize the capsaicin receptor TRPV1.

TRPV1 TRPA1

2.05e-052158228986540
Pubmed

Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain.

TRPV1 TRPA1

2.05e-052158230289972
Pubmed

H(2)S functions as a nociceptive messenger through transient receptor potential ankyrin 1 (TRPA1) activation.

TRPV1 TRPA1

2.05e-052158222641084
Pubmed

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization.

TRPV1 TRPA1

2.05e-052158228364279
Pubmed

Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction.

TRPV1 TACR1

2.05e-052158215499026
Pubmed

Identification of molecular targets for toxic action by persulfate, an industrial sulfur compound.

TRPV1 TRPA1

2.05e-052158230738091
Pubmed

TRPA1 as Target in Myocardial Infarction.

TRPV1 TRPA1

2.05e-052158236768836
Pubmed

Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.

SLC22A4 SLC22A5

2.05e-052158216333318
Pubmed

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.

SLC22A4 SLC22A5

2.05e-052158221793125
Pubmed

Neurochemical characterization of insulin receptor-expressing primary sensory neurons in wild-type and vanilloid type 1 transient receptor potential receptor knockout mice.

TRPV1 INSR

2.05e-052158217492627
Pubmed

Mutations in the genes KCND2 and KCND3 encoding the ion channels Kv4.2 and Kv4.3, conducting the cardiac fast transient outward current (ITO,f), are not a frequent cause of long QT syndrome.

KCND2 KCND3

2.05e-052158215563876
Pubmed

SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population.

SLC22A4 SLC22A5

2.05e-052158219659785
Pubmed

A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic.

TRPV1 TRPA1

2.05e-052158218297068
Pubmed

S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation.

KCND1 KCND2

2.05e-052158224675763
Pubmed

Characterization of organic cation/carnitine transporter family in human sperm.

SLC22A4 SLC22A5

2.05e-052158212788076
Pubmed

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

KCND2 KCND3

2.05e-052158226196737
Pubmed

Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3.

KCND2 KCND3

2.05e-052158210942109
Pubmed

Wu-tou decoction inhibits chronic inflammatory pain in mice: participation of TRPV1 and TRPA1 ion channels.

TRPV1 TRPA1

2.05e-052158225839032
Pubmed

Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis.

SLC22A4 SLC22A5

2.05e-052158221706137
Pubmed

A paradoxical protective role for the proinflammatory peptide substance P receptor (NK1R) in acute hyperoxic lung injury.

TRPV1 TACR1

2.05e-052158219633070
Pubmed

Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans.

PDE8A PDE8B

2.05e-052158212681444
Pubmed

Activation of Transient Receptor Potential Ankyrin 1 and Vanilloid 1 Channels Promotes Odontogenic Differentiation of Human Dental Pulp Cells.

TRPV1 TRPA1

2.05e-052158234126160
Pubmed

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.

NF1 KIT

2.05e-052158218984156
Pubmed

Chronotopic organization of olfactory bulb axons in the lateral olfactory tract.

NRP1 KIT

2.05e-052158215211465
Pubmed

Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity.

TRPV1 TRPA1

2.05e-052158225642661
Pubmed

Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.

NF1 KIT

2.05e-052158212393498
Pubmed

Mast cell-mediated inflammation relies on insulin-regulated aminopeptidase controlling cytokine export from the Golgi.

LNPEP KIT

2.05e-052158236708814
Pubmed

Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control.

TRPV1 TRPA1

2.05e-052158219074743
Pubmed

Neuro-immune interactions in chemical-induced airway hyperreactivity.

TRPV1 TRPA1

2.05e-052158227126687
Pubmed

TRPA1 and TRPV1 contribute to propofol-mediated antagonism of U46619-induced constriction in murine coronary arteries.

TRPV1 TRPA1

2.05e-052158228644897
Pubmed

A distinct role for transient receptor potential ankyrin 1, in addition to transient receptor potential vanilloid 1, in tumor necrosis factor α-induced inflammatory hyperalgesia and Freund's complete adjuvant-induced monarthritis.

TRPV1 TRPA1

2.05e-052158221360511
Pubmed

TRPA1 and TPRV1 Ion Channels Are Required for Contact Lens-Induced Corneal Parainflammation and Can Modulate Levels of Resident Corneal Immune Cells.

TRPV1 TRPA1

2.05e-052158237585189
Pubmed

cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor.

PDE8A PDE8B

2.05e-052158236277728
Pubmed

Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.

SLC22A4 SLC22A5

2.05e-052158222325173
Pubmed

Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.

TRPV1 TRPA1

2.05e-052158227170124
Pubmed

Molecular and functional characterization of organic cation/carnitine transporter family in mice.

SLC22A4 SLC22A5

2.05e-052158211010964
Pubmed

Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus.

KCND2 KCND3

2.05e-052158234386734
Pubmed

TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice.

TRPV1 TRPA1

2.05e-052158219893614
Pubmed

The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil.

TRPV1 TRPA1

2.05e-052158221315593
Pubmed

Gain-of-function mutations in the transient receptor potential channels TRPV1 and TRPA1: how painful?

TRPV1 TRPA1

2.05e-052158224564660
Pubmed

Are TRPA1 and TRPV1 channel-mediated signalling cascades involved in UVB radiation-induced sunburn?

TRPV1 TRPA1

2.05e-052158235248760
Pubmed

Knockout of the Tachykinin Receptor 1 in the Mdr2-/- (Abcb4-/-) Mouse Model of Primary Sclerosing Cholangitis Reduces Biliary Damage and Liver Fibrosis.

ABCB4 TACR1

2.05e-052158232712019
Pubmed

Mitochondrial modulation-induced activation of vagal sensory neuronal subsets by antimycin A, but not CCCP or rotenone, correlates with mitochondrial superoxide production.

TRPV1 TRPA1

2.05e-052158229734380
Pubmed

TRP Channels as Molecular Targets to Relieve Cancer Pain.

TRPV1 TRPA1

2.05e-052158235053150
InteractionPDE8B interactions

PDE8A PDE8B SNX27

7.64e-0661483int:PDE8B
InteractionSTX4 interactions

CAMLG TMEM51 SEC22B PLPPR1 LNPEP DHCR7 ITSN2 VPS13A PLEKHA1 SLC7A5 TACR1 RAB4A XPR1

1.70e-0542814813int:STX4
InteractionRHOA interactions

ERAP1 CAMLG CYP51A1 SPTLC1 SHMT2 SEC22B CLOCK MFSD12 CRMP1 DHX30 NRP1 NF1 SULT1A1 ARHGEF10 LNPEP DHCR7 SLC22A4 VPS13A ABCD3 PLEKHA1 SLC7A5 ATP11A XPR1

2.16e-05119914823int:RHOA
GeneFamilySolute carriers

SLC39A9 SLC6A17 SLC26A9 SLCO1B1 SLC22A7 SLC45A4 SLC5A2 SLC8A1 SLCO4C1 SLC16A6 SLC16A4 SLC18A1 SLC25A39 SLC22A4 SLC22A5 SLC13A5 SLC7A5

2.49e-0939512717752
GeneFamilyAminopeptidases|CD molecules

LVRN ERAP1 LNPEP

2.14e-04171273104
GeneFamilyGuanylate cyclase receptors

GUCY2F GUCY2D

1.00e-0371272343
GeneFamilyCytochrome P450 family 3

CYP3A7 CYP3A43

1.33e-03812721002
GeneFamilyADAM metallopeptidase domain containing|CD molecules

INSR NRP1 CXCR5 PLXNC1 ENTPD1 CD63 SLC7A5 CCR8 KIT

1.87e-033941279471
GeneFamilyPotassium voltage-gated channels

KCND1 KCND2 KCND3

2.77e-03401273274
GeneFamilyATP binding cassette subfamily A

ABCA10 ABCA5

4.22e-03141272805
GeneFamilyATPase phospholipid transporting

ATP11B ATP11A

4.84e-031512721210
GeneFamilyOlfactory receptors, family 8

OR8K5 OR8B8 OR8B12

4.93e-03491273155
GeneFamilyDEAH-box helicases

DHX30 DHX15

5.51e-03161272500
GeneFamilyDyneins, axonemal

DNAH1 DNAH8

6.21e-03171272536
GeneFamilyCadherin related

FAT3 PCDH15

6.21e-0317127224
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY40_UP

CACNA1S COPZ2 MFSD12 ABCA5 ARHGEF10 SLC22A5 SLC7A5 GSTO1 ADGRA3

2.54e-062001519M9316
CoexpressionAtlasdev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

STRN DHCR7 PLEKHA1 SLC7A5 KIT

4.40e-06361455gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k1_1000
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 SLC6A17 FAT3 DNAH1 COL24A1 SLC8A1 GUCY2F SCN9A PCDH15 PKHD1

1.29e-09184159102cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 SLC6A17 FAT3 DNAH1 COL24A1 SLC8A1 GUCY2F SCN9A PCDH15 PKHD1

1.29e-09184159102b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 SLC6A17 FAT3 DNAH1 COL24A1 SLC8A1 GUCY2F SCN9A PCDH15 PKHD1

1.29e-0918415910ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 SPTLC1 DNAH1 COL24A1 SLC18A1 SCN9A PCDH15 PKHD1 CD63

1.05e-08169159912bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A PCDH15 SETD7

2.11e-081831599121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A6 CPED1 NOP58 THBS4 MGST1 ZBED6 SCN7A CD63 GFPT2

3.19e-08192159911088878043a6ff95ba1970361256a82e434b80a
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM51 OR5H14 MYRFL CPED1 KLHL5 PTPRZ1 WNT16 SCN9A PCDH15

4.53e-0820015993cbb01039d1e7635ec4dcdf0223587f7ea3c7b34
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM51 OR5H14 MYRFL CPED1 KLHL5 PTPRZ1 WNT16 SCN9A PCDH15

4.53e-08200159997a010a1b6d551239cf6ea5a43319fb413ff180e
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM51 OR5H14 MYRFL CPED1 KLHL5 PTPRZ1 WNT16 SCN9A PCDH15

4.53e-0820015998ccf2dbbe34b26fbf2bbef1e64b4ae636edd6672
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A PCDH15

2.73e-071791598d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A PCDH15

3.09e-07182159808aff7112c9dac0ef5540300516a604782b21169
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 PTPRZ1 WNT16 SCN9A PCDH15

3.50e-071851598f4ac62009c0ad3346e71b809e17727303c4df153
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 PTPRZ1 WNT16 SCN7A SCN9A

3.80e-071871598d413fb4b1531b297af5012a392b88128510c2de8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYRFL SIM2 ARHGEF10L CRMP1 SLCO4C1 LNPEP PKHD1 PLEKHA1

3.80e-071871598c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM51 SIM2 CRMP1 LNPEP PKHD1 HRH1 PLEKHA1 ATP11A

4.12e-071891598aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM51 SIM2 CRMP1 LNPEP PKHD1 HRH1 PLEKHA1 ATP11A

4.12e-0718915988977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A PCDH15

4.65e-0719215980003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37|World / Primary Cells by Cluster

SLC6A17 SSTR2 GABBR2 NRP1 COL24A1 KLHL5 PDE8B KIT

5.64e-07197159800d756bc0231e1b3b88430214338c1059cb11106
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM51 PLPPR1 CPED1 KLHL5 PTPRZ1 WNT16 SCN7A SCN9A

6.33e-072001598fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM51 PLPPR1 CPED1 KLHL5 PTPRZ1 WNT16 SCN7A SCN9A

6.33e-0720015984a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TMEM51 PLPPR1 CPED1 KLHL5 PTPRZ1 WNT16 SCN7A SCN9A

6.33e-072001598c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPA1 NME8 ARHGEF10L GSDME KCND1 PLXNC1 SLC7A5

6.96e-071391597505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL24A1 CDH20 PTPRZ1 SCN7A CD63 RXFP1 KIT

1.86e-0616115973b5d7a3dab479c6959a428f3954dedd989900276
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TBC1D8B PLPPR1 COL24A1 PTPRZ1 SCN7A CD63 KIT

2.19e-061651597c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 WNT16 SCN9A PCDH15

3.36e-061761597682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 INSR PLPPR1 SLC22A7 PCDH15 SUFU CUX1

4.05e-061811597c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 SIM2 SLCO1B1 ARHGEF10L CRMP1 PKHD1 HRH1

4.05e-061811597071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZYG11A SSTR2 PLPPR1 SLC22A7 SLC5A2 SLCO4C1 PKHD1

4.05e-0618115976980ea624151da32b7f537f263e40fcb87a02e81
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 SLCO1B1 ARHGEF10L CRMP1 BTBD16 PKHD1 PLEKHA1

4.20e-061821597eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

STAB2 FAT3 PLPPR1 THBS4 DHCR7 SCN9A KIT

4.35e-061831597ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPED1 ABCA10 NRP1 SLC8A1 KCND2 KCND3 RXFP1

4.51e-061841597e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

STAB2 FAT3 PLPPR1 THBS4 DHCR7 SCN9A KIT

4.51e-06184159758d36577eff814d46d72f031f3533d71549e3d6e
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

INSR SLC22A7 SLC5A2 NRP1 MGST1 SLC22A5 PKHD1

5.01e-061871597738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A PCDH15

5.19e-0618815978de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 ARHGEF10L CRMP1 SLCO4C1 LNPEP PKHD1 PLEKHA1

5.57e-0619015971cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT3 PLPPR1 NRP1 THBS4 DHCR7 SCN9A KIT

5.57e-06190159705a2c3549b68f49081723bf35db14974274419d5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A TACR1

5.57e-0619015973f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPR155 CPED1 NRP1 SLC8A1 ENTPD1 SCN9A HRH1

5.57e-061901597f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 ARHGEF10L CRMP1 SLCO4C1 LNPEP PKHD1 PLEKHA1

5.57e-06190159759bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 PTPRZ1 WNT16 SCN9A

5.57e-061901597305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN COL6A6 NOP58 MGST1 ZBED6 SCN7A CD63

5.76e-0619115977d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

SLC6A17 GPX2 SLC26A9 CRMP1 KCND3 SLC18A1 SCN9A

5.76e-06191159776311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A

6.17e-061931597c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 STRN PKHD1 HRH1 PLEKHA1 ATP11A ADGRA3

6.17e-06193159742df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 STRN PKHD1 HRH1 PLEKHA1 ATP11A ADGRA3

6.17e-061931597f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 STRN PKHD1 HRH1 PLEKHA1 ATP11A ADGRA3

6.38e-061941597e577d9e88390b36b5a09b97fe1026089892275a3
ToppCelldroplet-Mammary_Gland-nan-18m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB4 TMEM51 NOP58 SCN7A CD63 GSTO1 ADGRA3

6.82e-061961597558324d7779463fd5cd438aee7d0f86be7366d3f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

EML6 SSTR2 NRP1 KCND1 SETD7 CUX1

7.04e-06129159664768adf23123b92280fb30eb85147cbee084ae0
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A6 FAT3 CPED1 ABCA10 NRP1 SCN7A GFPT2

7.78e-062001597cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A6 FAT3 ABCA10 NRP1 KCND2 SCN7A GFPT2

7.78e-062001597cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A6 FAT3 ABCA10 NRP1 SCN7A PCDH15 GFPT2

7.78e-062001597311fab076f2ceb258e3970eb21e39344b894042a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CDH20 PTPRZ1 SCN7A SCN9A CD63 GFPT2

9.94e-061371596d346086f42d8f04d3fa67fe696834284acdc7080
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Wif1_(Medial_habenular,_lateral_portion)|Thalamus / BrainAtlas - Mouse McCarroll V32

LVRN GPX2 VWDE SLC22A7 SLC5A2

1.00e-05801595da18df34b4f630fe4fe3110e3c3c3602aef92aab
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NME8 ABCB4 KLHL5 PLXNC1 SCN9A ADGRA3

1.27e-0514315965a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NME8 ABCB4 KLHL5 PLXNC1 SCN9A ADGRA3

1.37e-051451596997bd540c43725a85ca97e4b79ebe0d336860287
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLPPR1 COL24A1 PTPRZ1 CD63 RXFP1 KIT

1.43e-05146159647368f981180ca6a8c81a50f7f9430f12456f609
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL24A1 PTPRZ1 WNT16 SCN7A CD63 KIT

2.08e-051561596896e2d958be0a5c62fb6eebad2dfb7e1ce69f3ad
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

FAT3 GABBR2 KCND2 PCDH15 RXFP1 DNAH8

2.32e-0515915965335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FA2H FAT3 BTBD16 TM4SF4 PKHD1 TTLL13

2.48e-051611596f5df8c6a340d5026726804b103e32137f363ca40
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL24A1 PTPRZ1 WNT16 SCN7A CD63 KIT

2.48e-051611596be77e99faf653480c166305df3a4e93db76f0dcb
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT3 ABCA5 GUCY2F SCN9A PCDH15 PKHD1

2.57e-051621596bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWDE CDH20 KCND2 KCND3 SLC18A1 TM4SF4

2.76e-051641596be49af6335f2505065cde2cb9800e4a5516811b1
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP51A1 SLC22A7 SLCO4C1 SLC16A4 SLC18A1 ATP11A

3.15e-05168159635ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL24A1 PTPRZ1 SCN7A CD63 RXFP1 KIT

3.15e-051681596f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM51 ERN2 PLPPR1 MGST1 TACR1 GSTO1

3.26e-05169159608ac28c5ad8f5c5f9f54af341bf39e8f9417636e
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM51 ERN2 PLPPR1 MGST1 TACR1 GSTO1

3.26e-051691596e5abd41db1e6724ad900e37658fa063b8e522908
ToppCellfacs-Heart-LV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 GJB4 TBX21 BTBD16 GIMAP8 CCR8

3.37e-0517015962491f3849e34b0ccd06015fa59d15e3d7963c76d
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 TMEM51 SLC8A1 SULT1A1 GSTO1 KIT

3.37e-051701596670027daec5a10dfa12246f1497b58db21d32a22
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR5 SLC8A1 NF1 KCND1 PLXNC1 KIT

3.60e-051721596438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR5 SLC8A1 NF1 KCND1 PLXNC1 KIT

3.60e-051721596356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP3A7 GJB4 GPX2 GSDME PTPRZ1 PKHD1

3.60e-051721596e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR5 SLC8A1 NF1 KCND1 PLXNC1 KIT

3.60e-05172159646fadeee483fdf8402df92ec98575a09c6c15b16
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

NME8 NRP1 COL24A1 MGST1 SCN9A SLC7A5

4.09e-051761596ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell(06)_Krt4/13+-(1)_24hpi|(06)_Krt4/13+ / shred by cell type and Timepoint

KLHL28 GJB4 SLC16A6 DNAH8

4.14e-05541594c89ac09a4bf42f413a1be392b25d98d3ede683a0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 PLPPR1 CPED1 KLHL5 WNT16 SCN7A

4.22e-0517715965e0fca9bd5e5ffe6d39f5bcd81f36512f3b0cb1b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYRFL CPED1 KLHL5 WNT16 SCN7A SCN9A

4.36e-0517815966ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SSTR2 NRP1 COL24A1 KLHL5 MGST1 RXFP1

4.36e-051781596431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZYG11A INSR SLC22A7 SLC5A2 SCN9A PCDH15

4.64e-0518015961363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

STAB2 FAT3 PLPPR1 THBS4 SCN9A KIT

4.64e-0518015968af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SLC8A1 GSDME CDH20 ENTPD1 SCN7A SCN9A

4.64e-051801596289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCellmild-Myeloid-pDC|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CPED1 NRP1 COL24A1 GUCY2D SCN9A SLC7A5

4.64e-05180159638614155fa537d0defda914c531c697be0ef06d8
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPX2 ERN2 MGST1 SCN9A ATP11A GSTO1

4.78e-051811596092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL6A6 FAT3 ABCA10 NRP1 SCN7A PCDH15

4.78e-0518115969ede19228ba5c0668a9c06c915510b95585216ef
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CPED1 KLHL5 PTPRZ1 WNT16 SCN7A SCN9A

4.78e-051811596af92b8b7f455210dab502ef6964f3a0162180759
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 SLCO1B1 ARHGEF10L CRMP1 PKHD1 PLEKHA1

4.78e-0518115969d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RRAGB PLPPR1 PTPRZ1 CD63 GFPT2 KIT

4.93e-051821596f2a1784ffcba9b27132e0db21e574cbd8a0a6418
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZYG11A INSR SLC26A9 SLC22A7 NRP1 CUX1

4.93e-0518215964a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 CPED1 KLHL5 WNT16 SCN7A PCDH15

4.93e-051821596a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCelldroplet-Kidney-nan-21m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP51A1 SLC22A7 SLC5A2 SLC25A39 ABCD3 CD63

4.93e-051821596942c18a27b22fb33a5200d5717cad972f3ef0576
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

INSR ERN2 MGST1 PTPRZ1 PDE8B TACR1

4.93e-0518215963f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZYG11A INSR SLC22A7 SLC5A2 SLC22A5 PCDH15

5.08e-05183159684b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM51 MYRFL CPED1 WNT16 SCN9A PCDH15

5.08e-0518315965a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZYG11A PLPPR1 SLC22A7 SLC5A2 SLC22A5 PCDH15

5.08e-051831596facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NME8 ABCB4 KLHL5 SLC18A1 PLXNC1 ENTPD1

5.24e-0518415960a26bcc6610f756939e32a4d6dfeebcbf3a1db86
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 EML6 SIM2 CRMP1 PKHD1 HRH1

5.24e-051841596da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPR155 CPED1 NRP1 SLC8A1 SCN9A HRH1

5.40e-0518515968207f9eff113eed429e961748c6b17d672a13b33
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZYG11A SLC22A7 SLC5A2 SLC22A5 PCDH15 PKHD1

5.56e-0518615965784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A7 NRP1 SLC22A4 PKHD1 PLEKHA1 ATP11A

5.56e-051861596b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellcontrol-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

GPX7 NRP1 COL24A1 GUCY2D SCN9A SLC7A5

5.56e-051861596fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC26A9 PLPPR1 VWDE PTPRZ1 PKHD1 ATP11A

5.56e-051861596bb0bfe9a015151be08a6ffc5d82896d0556d76de
Drugverapamil

CACNA1S CYP3A7 TRPA1 SLCO1B1 ABCA10 ABCB4 ABCA5 KCND1 KCND2 KCND3 SLC22A4 SLC22A5 SCN7A SCN9A ABCD3 HRH1 CACNA1I

5.31e-0849015717CID000002520
Drugquindine

CYP3A7 SLCO1B1 ABCB4 KCND1 KCND2 KCND3 SLC22A4 SLC22A5 SCN7A SCN9A HRH1

3.72e-0721915711CID000001065
Drugsodium

CACNA1S TRPV1 SPTLC1 SLC26A9 GABBR2 SLCO1B1 SLC5A2 SLC8A1 ATP11B KCND2 KCND3 SLC18A1 SLC22A4 SLC22A5 SCN7A SCN9A SLC13A5 SLC7A5 ATP11A TACR1 GFPT2

2.24e-0694415721CID000000923
Drugbutamben

KCND1 KCND2 KCND3 CACNA1I

2.80e-06151574CID000002482
Drugtetraethylammonium

CACNA1S GABBR2 SLC22A7 KCND1 KCND2 KCND3 GUCY2F SLC22A4 SLC22A5 SCN9A

5.86e-0623615710CID000005413
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

CYP3A7 TRPV1 GABBR2 NME8 ABCB4 ARHGEF10 SLC18A1 PDE8B CACNA1I

8.76e-0619515796183_UP
Drugpyraclofos

CACNA1S KCND1 KCND2 KCND3 SCN7A SCN9A CACNA1I

8.92e-061061577CID000093460
DrugSuprofen [40828-46-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A

STAB2 GABBR2 CPED1 CRMP1 NF1 ARHGEF10 KCND3 CACNA1I ATP11A

9.51e-0619715794123_DN
Druggabapentin

CACNA1S TRPA1 GABBR2 SCN7A SCN9A SLC7A5 CACNA1I GFPT2

2.33e-051691578CID000003446
Drugfelodipine

CACNA1S CYP3A7 TRPA1 PDE8A CYP3A43 CYP51A1 PDE8B CACNA1I

2.33e-051691578CID000003333
Drug8-Bromo Cyclic Adenosine Monophosphate

CYP3A7 TRPA1 HDAC5 ERAP1 CYP51A1 GABBR2 NRP1 KLHL5 GIMAP8 SLCO4C1 SLC16A6 MGST1 KCND2 PTPRZ1 DHCR7 GFPT2

2.52e-0569315716ctd:D015124
DrugCinnarizine

CACNA1S HRH1 CACNA1I

2.62e-0591573DB00568
Drugbepridil

CACNA1S TRPA1 KCND3 SCN7A SCN9A SLC13A5 CACNA1I

2.76e-051261577CID000002351
DrugGabexate mesilate [56974-61-9]; Up 200; 9.6uM; HL60; HT_HG-U133A

SIN3B INSR PLPPR1 NRP1 NF1 PDE8B WNT16 ENTPD1

3.66e-0518015782937_UP
DrugThioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A

FA2H ABHD3 MSH2 ERN2 CLOCK ATP11B ITSN2 KIF11

5.38e-0519015782619_DN
Drugclotrimazole

CYP3A7 CYP3A43 CYP51A1 SLCO1B1 MGST1 KCND1 GSTO1

6.19e-051431577CID000002812
DrugPhenacetin [62-44-2]; Down 200; 22.4uM; MCF7; HT_HG-U133A

STAB2 COPZ2 TMEM104 PLPPR1 PDE8B CDADC1 ATP11A CUX1

6.22e-0519415784111_DN
Drugrapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; PC3; HT_HG-U133A

ERAP1 GABBR2 PLPPR1 KCND3 PDE8B ENTPD1 CDADC1 CACNA1I

6.45e-0519515785980_DN
DrugIressa; Up 200; 10uM; HL60; HG-U133A

ERAP1 SSTR2 CPED1 DTX4 ENTPD1 ITSN2 SLC7A5 CCR8

6.45e-051951578541_UP
DrugProgesterone [57-83-0]; Up 200; 12.8uM; HL60; HT_HG-U133A

PLPPR1 CPED1 NRP1 NF1 SLC16A4 SLC22A5 ENTPD1 CACNA1I

6.45e-0519515782426_UP
DrugCefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; HL60; HT_HG-U133A

RRAGB SIM2 CPED1 SLC22A7 CRMP1 STRN PDE8B TACR1

6.69e-0519615782988_UP
DrugFolic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A

STAB2 COPZ2 HDAC5 FA2H SIM2 ENTPD1 CACNA1I ATP11A

6.69e-0519615782783_UP
Drug(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A

PLPPR1 SLCO1B1 NRP1 STRN NF1 KCND3 ENTPD1 TACR1

6.69e-0519615784524_UP
DrugCanavanine sulfate monohydrate (L,+) [206996-57-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

SLC39A9 ERAP1 ABHD3 TMEM104 MSH2 ERN2 GPR107 DHX15

6.69e-0519615784782_DN
DrugVitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A

COPZ2 SLC39A9 SPTLC1 GABBR2 ERN2 NRP1 STRN NF1

6.93e-0519715783798_DN
DrugSulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

SLC39A9 INSR SIM2 ABCB4 PLXNC1 WNT16 CACNA1I ATP11A

6.93e-0519715783940_UP
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

TBC1D8B CPED1 SLC5A2 ABCB4 NF1 KCND3 CACNA1I CCR8

6.93e-0519715783605_UP
DrugMetoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A

TRPV1 RRAGB SIM2 SLC5A2 NF1 GUCY2D CACNA1I ATP11A

7.18e-0519815786106_UP
DrugMefenamic acid [61-68-7]; Up 200; 16.6uM; MCF7; HT_HG-U133A

ERAP1 ERN2 NF1 PLXNC1 WNT16 ENTPD1 PLEKHA1 CACNA1I

7.44e-0519915781699_UP
DrugAlprenolol hydrochloride [13707-88-5]; Up 200; 14uM; PC3; HT_HG-U133A

TRPV1 FA2H ERN2 NF1 LNPEP PDE8B HRH1 PLEKHA1

7.44e-0519915787141_UP
DrugFolic acid [59-30-3]; Up 200; 9uM; PC3; HT_HG-U133A

STAB2 HDAC5 ERAP1 SPTLC1 ABHD3 RRAGB GABBR2 SLC5A2

7.44e-0519915785844_UP
DrugKhellin [82-02-0]; Up 200; 15.4uM; MCF7; HT_HG-U133A

TRPV1 STAB2 HDAC5 INSR SLC5A2 PLXNC1 GUCY2D CACNA1I

7.70e-0520015781504_UP
DrugBetazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A

ERAP1 TBX21 PLPPR1 NF1 KCND3 CDADC1 CACNA1I KIT

7.70e-0520015785445_UP
DrugCinoxacin [28657-80-9]; Up 200; 15.2uM; HL60; HT_HG-U133A

COPZ2 CRMP1 PLXNC1 GUCY2D WNT16 PLEKHA1 CACNA1I ACKR2

7.70e-0520015782722_UP
DrugDipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A

STAB2 COPZ2 ERAP1 GABBR2 KCND1 PLXNC1 CDADC1 CACNA1I

7.70e-0520015786766_UP
DrugMeropenem [96036-03-2]; Up 200; 10.4uM; HL60; HT_HG-U133A

TRPV1 SSTR2 GABBR2 PLPPR1 SLC5A2 SLC22A5 TM4SF4 ACKR2

7.70e-0520015786141_UP
DrugS(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; HL60; HT_HG-U133A

CYP3A43 RRAGB GPR107 NRP1 SLC16A4 WNT16 SCN7A PLEKHA1

7.70e-0520015783056_UP
DrugEtifenin [63245-28-3]; Up 200; 12.4uM; HL60; HT_HG-U133A

SIM2 NRP1 SLC16A4 GUCY2F PDE8B CACNA1I ACKR2 KIT

7.70e-0520015782477_UP
Drugmanganese chloride

ERAP1 FA2H INSR GABBR2 CLOCK NRP1 STRN ABCA5 SCN7A VPS13A HRH1 TACR1

8.00e-0545615712ctd:C025340
DrugAllopurinol

INSR SLC22A7 SLC8A1 SLC22A4 SLC22A5

9.31e-05661575ctd:D000493
Drugpantoprazole

CYP3A7 CYP3A43 ABCD3 HRH1

9.65e-05351574CID000004679
DrugGlutathione

GPX2 GPX7 MGST1 GSTO1

1.08e-04361574DB00143
Drugamiodarone

SLCO1B1 ABCB4 KCND2 KCND3 SCN7A SCN9A TAAR1

1.25e-041601577CID000002156
Drugflecainide

KCND1 KCND2 KCND3 SCN7A SCN9A

1.32e-04711575CID000003355
Drugmorphine hydrochloride

TRPA1 INSR GABBR2 SLCO1B1 ABCB4 CXCR5 GSDME SCN9A HRH1 TACR1 CCR8 ACKR2

1.32e-0448115712CID000004253
DrugE 4021

PDE8A PDE8B

1.41e-0431572ctd:C091517
DrugGR 73632

TRPV1 TACR1

1.41e-0431572ctd:C068032
DrugClemastine

ABCB4 HRH1

1.41e-0431572ctd:D002974
Drugdimethylaminopyridine

INSR ACKR2

1.41e-0431572CID000021885
DrugVapreotide

SSTR2 TACR1

1.41e-0431572DB04894
Drugtalinolol

SLCO1B1 SLC22A5

1.41e-0431572ctd:C011550
DiseaseColorectal Carcinoma

MSH2 ABCA10 ARHGEF10L ABCB4 NF1 ABCA5 KCND3 WNT16 VPS13A ABCD3 PKHD1 HRH1 DNAH8 CUX1

1.61e-0570215114C0009402
Diseasesleep disorder (implicated_via_orthology)

INSR CLOCK NF1

2.10e-05111513DOID:535 (implicated_via_orthology)
DiseaseSneezing

TRPV1 TRPA1

2.60e-0521512C0037383
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

SLCO1B1 SLC22A4 SLC22A5

3.62e-05131513EFO_0800547
Diseaseneuroligin-1 measurement

STAB2 SPATA16

7.78e-0531512EFO_0802802
Diseaseserum metabolite measurement

CYP3A7 TRPA1 PDE8A ERAP1 CYP3A43 FA2H SLCO1B1 CPED1 SLC45A4 ABCB4 SLC22A4 SLC22A5 PCDH15 SLC7A5 TAAR1

1.08e-0494515115EFO_0005653
Diseasemetabolonic lactone sulfate measurement

CYP3A7 CYP3A43 SLCO1B1

1.20e-04191513EFO_0800659
Diseasevaginal discharge, Metrorrhagia

CPED1 WNT16

1.55e-0441512EFO_0009365, HP_0100608
DiseaseN-oleoylserine measurement

FA2H SLCO1B1

1.55e-0441512EFO_0800525
Diseaseestrone conjugate measurement

CYP3A7 SLCO1B1

1.55e-0441512EFO_0007971
DiseaseN-oleoyltaurine measurement

FA2H SLCO1B1

1.55e-0441512EFO_0800337
DiseaseCoughing

TRPV1 TRPA1

1.55e-0441512C0010200
Diseaseanti-human herpes virus 7 antibody measurement

TBX21 CXCR5

2.58e-0451512EFO_0011038
Diseasereticulocyte count

INSR EML6 SLCO1B1 SLC45A4 ABCB4 NRP1 STRN CDH20 GIMAP8 ATP11B SLC22A4 SLC22A5 VPS13A ATP11A CUX1

3.18e-04104515115EFO_0007986
DiseaseCoxsackievirus Infections

SLC22A4 SLC22A5

3.85e-0461512C0010246
DiseaseMyocarditis

SLC22A4 SLC22A5

3.85e-0461512C0027059
DiseaseCarditis

SLC22A4 SLC22A5

3.85e-0461512C0869523
DiseaseAutistic Disorder

GPR155 CHD8 GABBR2 NF1 KCND2 DHCR7 SCN7A

4.09e-042611517C0004352
Diseasesensory perception of smell

STAB2 PLPPR1 DHX15

4.35e-04291513GO_0007608
DiseaseInflammation

TRPV1 TRPA1 TBX21 ABCB4 SLC22A5

5.06e-041271515C0021368
Diseasepleckstrin homology domain-containing family A member 1 measurement

BTBD16 PLEKHA1

5.37e-0471512EFO_0802873
Diseaseendoplasmic reticulum aminopeptidase 1 measurement

ERAP1 LNPEP

5.37e-0471512EFO_0008119
DiseaseLung diseases

INSR NME8 GSTO1 KIT

7.01e-04781514C0024115
Diseasesevere pre-eclampsia (is_marker_for)

ERAP1 LNPEP

7.14e-0481512DOID:13129 (is_marker_for)
Diseaseacetylcarnitine measurement

SLC22A4 SLC22A5

7.14e-0481512EFO_0021038
DiseaseSudden Cardiac Arrest

KCND2 KCND3

7.14e-0481512C1720824
DiseasePruritus

SCN9A HRH1

7.14e-0481512C0033774
Diseasebutyrylcarnitine measurement

SLC22A4 SLC22A5

7.14e-0481512EFO_0020010
Diseasenervonoylcarnitine (C24:1) measurement

SLC22A4 SLC22A5

9.15e-0491512EFO_0800549
Diseasethoracic aortic calcification measurement

COL6A6 VPS13A

9.15e-0491512EFO_0010273
DiseaseAllodynia

TRPV1 TRPA1 INSR TACR1

9.25e-04841514C0458247
DiseaseMechanical Allodynia

TRPV1 TRPA1 INSR TACR1

9.25e-04841514C2936719
DiseaseHyperalgesia, Secondary

TRPV1 TRPA1 INSR TACR1

9.25e-04841514C0751212
DiseaseHyperalgesia, Primary

TRPV1 TRPA1 INSR TACR1

9.25e-04841514C0751211
DiseaseHyperalgesia, Thermal

TRPV1 TRPA1 INSR TACR1

9.25e-04841514C0751214
DiseaseTactile Allodynia

TRPV1 TRPA1 INSR TACR1

9.25e-04841514C0751213
DiseaseHyperalgesia

TRPV1 TRPA1 INSR TACR1

9.25e-04841514C0020429
DiseaseDegenerative Diseases, Central Nervous System

MGST1 PDE8B GSTO1

1.05e-03391513C0270715
DiseaseNeurodegenerative Disorders

MGST1 PDE8B GSTO1

1.05e-03391513C0524851
DiseaseLewy body dementia

SLC26A9 PLXNC1 HRH1

1.05e-03391513EFO_0006792
Diseasebone quantitative ultrasound measurement

CPED1 GIMAP8 WNT16

1.05e-03391513EFO_0004514
DiseaseDegenerative Diseases, Spinal Cord

MGST1 PDE8B GSTO1

1.05e-03391513C0751733
Diseaseneutrophil count, basophil count

EML6 SLC45A4 SLC22A4 ITSN2 ACKR2 KIT

1.07e-032241516EFO_0004833, EFO_0005090
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN7A SCN9A

1.14e-03101512DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN7A SCN9A

1.14e-03101512DOID:0080422 (implicated_via_orthology)
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

CYP3A7 SLCO1B1

1.14e-03101512EFO_0022090
Diseasealpha wave measurement, electroencephalogram measurement

MSH2 DNAH1

1.14e-03101512EFO_0004357, EFO_0006870
DiseaseCutaneous Melanoma

NF1 KIT CUX1

1.21e-03411513C0151779
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

LVRN SLCO4C1

1.39e-03111512EFO_0801871
Diseaselignoceroylcarnitine (C24) measurement

SLC22A4 SLC22A5

1.39e-03111512EFO_0800541
Diseaseandrostenediol (3beta,17beta) monosulfate (2) measurement

CYP3A7 SLCO1B1

1.39e-03111512EFO_0800295
DiseaseLenticulostriate Disorders

PDE8B XPR1

1.66e-03121512C0750951
DiseaseExtrapyramidal Disorders

PDE8B XPR1

1.66e-03121512C0015371
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN7A SCN9A

1.66e-03121512DOID:0060170 (implicated_via_orthology)
Diseasearachidonoylcarnitine (C20:4) measurement

SLCO1B1 SLC22A4

1.66e-03121512EFO_0800544
Diseasetryptophan betaine measurement

SLC22A4 SLC22A5

1.66e-03121512EFO_0021017
Diseasehexanoylcarnitine measurement

SLC22A4 SLC22A5

1.66e-03121512EFO_0021040
DiseaseBasal Ganglia Diseases

PDE8B XPR1

1.66e-03121512C0004782
Diseasechildhood onset asthma

TBX21 INSR CXCR5 KLHL5 SLC7A5 KIF11 XPR1

1.72e-033341517MONDO_0005405
Diseasevelocity of sound measurement

CPED1 WNT16

1.96e-03131512EFO_0005654
Diseasehomostachydrine measurement

SLC22A4 SLC22A5

1.96e-03131512EFO_0021164
Diseasemale infertility (implicated_via_orthology)

SPATA16 KIT

1.96e-03131512DOID:12336 (implicated_via_orthology)
Diseasecerotoylcarnitine (C26) measurement

SLC22A4 SLC22A5

1.96e-03131512EFO_0800542
DiseaseHereditary Motor and Sensory-Neuropathy Type II

SPTLC1 SCN9A

1.96e-03131512C0270914
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

CYP3A7 SLCO1B1

1.96e-03131512EFO_0800293
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

CYP3A7 SLCO1B1

1.96e-03131512EFO_0800284
Diseasegranulocyte count

EML6 SLC45A4 SLC22A4 SNX27 ACKR2 KIT

2.02e-032541516EFO_0007987
DiseasePain, Migratory

TRPV1 TRPA1 HRH1

2.04e-03491513C0751407
DiseaseSuffering, Physical

TRPV1 TRPA1 HRH1

2.04e-03491513C0751408
Diseasecholestasis (biomarker_via_orthology)

SLCO1B1 CLOCK ABCB4

2.04e-03491513DOID:13580 (biomarker_via_orthology)
DiseasePain, Crushing

TRPV1 TRPA1 HRH1

2.04e-03491513C0458259
DiseasePain, Splitting

TRPV1 TRPA1 HRH1

2.04e-03491513C0458257
DiseasePain

TRPV1 TRPA1 HRH1

2.04e-03491513C0030193
DiseaseRadiating pain

TRPV1 TRPA1 HRH1

2.04e-03491513C0234254
DiseasePain, Burning

TRPV1 TRPA1 HRH1

2.04e-03491513C0234230
DiseaseAche

TRPV1 TRPA1 HRH1

2.04e-03491513C0234238
DiseaseX-21470 measurement

CYP3A7 SLCO1B1

2.27e-03141512EFO_0800817
Diseasediabetic neuropathy (implicated_via_orthology)

TRPA1 INSR

2.27e-03141512DOID:9743 (implicated_via_orthology)
Diseasecorpus callosum posterior volume measurement

STRN WNT16 SUFU

2.42e-03521513EFO_0010298
Diseasemetabolite measurement

CYP3A43 FA2H INSR SHMT2 SLCO1B1 SLC45A4 SLC22A4 SLC22A5 SLC13A5

2.45e-035601519EFO_0004725
DiseaseCiliopathies

GUCY2D PCDH15 PKHD1 DNAH8

2.50e-031101514C4277690
DiseaseX-12063 measurement

CYP3A7 PDE8A SIM2 SLCO1B1 NF1

2.75e-031861515EFO_0021283
Diseasekeratinocyte carcinoma

SLC6A17 STRN ATP11A CUX1

3.22e-031181514EFO_0010176
Diseasepre-malignant neoplasm (biomarker_via_orthology)

INSR SUFU

3.36e-03171512DOID:0060071 (biomarker_via_orthology)
Diseasepain

TMEM51 MSH2 LCLAT1 SPATA16 PLEKHA1

3.44e-031961515EFO_0003843
Diseasemicroglial activation measurement

FAT3 SLC8A1 ADGRA3

3.46e-03591513EFO_0010940
Diseasehypothyroidism

TBX21 INSR PLXNC1 PDE8B PLEKHA1 CCR8

3.51e-032841516EFO_0004705
DiseaseMalignant neoplasm of breast

GPX2 SPTLC1 SLCO1B1 NME8 CXCR5 NF1 CDH20 SULT1A1 GUCY2F ITSN2 FGF4 KIT CUX1

3.59e-03107415113C0006142
DiseaseSjogren syndrome

CXCR5 PDE8B ITSN2

3.63e-03601513EFO_0000699
Diseaseneuroimaging measurement, brain volume measurement

PDE8A FAT3 CPED1 STRN NF1 SULT1A1

3.63e-032861516EFO_0004346, EFO_0006930
DiseaseMalignant neoplasm of endometrium

MSH2 CUX1

3.77e-03181512C0007103
DiseaseCarcinoma in situ of endometrium

MSH2 CUX1

3.77e-03181512C0346191
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

CYP3A7 SLCO1B1

3.77e-03181512EFO_0800288
Diseasebone density

COPZ2 HDAC5 CPED1 NME8 BTBD16 SLC8A1 WNT16

3.95e-033881517EFO_0003923
DiseaseCholecystitis

ABCB4 TM4SF4

4.20e-03191512HP_0001082
Diseaseoleoylcarnitine measurement

SLC22A4 SLC22A5

4.20e-03191512EFO_0021043
DiseaseMalignant Neoplasms

TRPV1 GSTO1 KIT CUX1

4.30e-031281514C0006826
Diseaserenal cell carcinoma (is_marker_for)

INSR MSH2 LNPEP KIT

4.30e-031281514DOID:4450 (is_marker_for)
DiseaseHeadache

SNX27 PLEKHA1 CUX1

4.36e-03641513HP_0002315
Diseasealcohol consumption measurement

DDX55 SLC45A4 DHX15 SLC8A1 NF1 SULT1A1 KCND2 PKHD1 CDADC1 CACNA1I SUFU KIT CUX1 XPO7

4.75e-03124215114EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
FVGVVFKDSMSYELR

ABCA5

126

Q8WWZ7
ITEITFFMGYTIATI

ABCA5

1151

Q8WWZ7
VFGSFLCKMVSTLYT

ACKR2

111

O00590
KMGEVFTDLCVYFFT

CAMLG

266

P49069
VFVASFSKSMVLDAY

ARHGEF10

501

O15013
LFVASFSKSMVLDVY

ARHGEF10L

396

Q9HCE6
GAYKFDALITTFEMI

CHD8

916

Q9HCK8
MASFKAVFVPVAYSL

CXCR5

46

P32302
VVDTFTITMGRYKEF

CPED1

931

A4D0V7
KYHEMVGVIFSDTFS

ABCA10

31

Q8WWZ4
SYKMIATFFILAFDT

ABCA10

306

Q8WWZ4
AIPTYETVMTFFKSF

BTBD16

291

Q32M84
ALEAYVIKSTGFTGM

ADGRA3

541

Q8IWK6
EIAFFGGMTIVYKNS

COPZ2

91

Q9P299
DAGSKQLFMTAYFLV

GSDME

376

O60443
KRFTSVMFGYQTIDD

ABHD3

306

Q8WU67
SYMRFGELEGVSKFT

CDADC1

456

Q9BWV3
ELFDIFTYSKGASMA

LVRN

496

Q6Q4G3
MSATLDAGKFQIYFD

DHX15

291

O43143
YFMAVKSNGSVFVRD

DHX30

1076

Q7L2E3
VSTFAMVKGYFFPTS

DHCR7

191

Q9UBM7
LTSIGFSYVIDFNTM

DTX4

126

Q9Y2E6
FFVVSESFILSAMAY

OR8B8

106

Q15620
MSETYDFLFKFLVIG

RAB4A

6

P20338
FFKDGYMVVNVSSLS

GPR107

61

Q5VW38
LTYMVKQFAVSSGSE

ITSN2

1461

Q9NZM3
YMSDVKRISATSIFF

SHMT2

176

P34897
KRISATSIFFESMPY

SHMT2

181

P34897
AIAGYVFRDKVMSEF

CD63

101

P08962
SESLVVMAYAKFSGA

MTX3

21

Q5HYI7
MLVLFETSVGYAIFK

NOP58

1

Q9Y2X3
KISYTDSSINFLMVF

OR5H14

186

A6NHG9
YSTFQALMFTIKIFT

OR8K5

151

Q8NH50
FYAFGVTDTLVIAVM

OR1B1

106

Q8NGR6
AIIIFATVMFYAEKG

KCND1

336

Q9NSA2
AIIIFATVMFYAEKG

KCND3

331

Q9UK17
ATVMFYAEKGSSASK

KCND3

336

Q9UK17
KTTFFGGNSISMIDY

GSTO1

161

P78417
SFSYQVAKGMAFLAS

KIT

771

P10721
LYFSDIVGFTTISAM

GUCY2D

881

Q02846
DSAFFYGKEQMITTA

GPR155

511

Q7Z3F1
YTFDMVFGASTKQID

KIF11

66

P52732
EVFMAFASYATIILS

MGST1

11

P10620
MTLYVGKDETGFYVS

ERN2

286

Q76MJ5
TYFIKQDSKSFGIMV

LCLAT1

26

Q6UWP7
VLSNKMARTIGFFYT

CUX1

611

Q13948
AVFEKGMKAFVSYVQ

DDX55

416

Q8NHQ9
FDVTVKMSTYLVAFI

ERAP1

236

Q9NZ08
KMSTYLVAFIISDFE

ERAP1

241

Q9NZ08
EGFAKFMEFVSVSVT

ERAP1

376

Q9NZ08
YKDVSVVNVMFSFGS

PLXNC1

566

O60486
VSIFGVASRFFVAMS

FGF4

126

P08620
FIDTVYSTAFAPKMI

OR4A15

96

Q8NGL6
YVTLAGSEFFLLATM

OR2T4

136

Q8NH00
YARPFSTFSVDKMVS

OR4Q2

256

P0C623
KSQISFIDYFITDMF

PDE8A

776

O60658
KSQISFIDYFITDMF

PDE8B

831

O95263
SGEKSFEVSEMYIFG

DNAH8

346

Q96JB1
AFGISSTPYSFKVMA

ABCC11

1066

Q96J66
EMFYLKVFGTKVEAT

MYRFL

291

Q96LU7
IIFATVMFYAEKGSS

KCND2

336

Q9NZV8
VMFYAEKGSSASKFT

KCND2

341

Q9NZV8
CVMTLLYAFSKDIFS

SLC7A5

381

Q01650
SVKMSTYLVAFIVGE

LNPEP

351

Q9UIQ6
FTVKIGDFGMTRDIY

INSR

1171

P06213
YGTLFFMYVQTKVTS

OR6Q1

256

Q8NGQ2
KTISFYGCMTQIIVF

OR2D3

106

Q8NGH3
EFGSESGVLYKTLMF

PTPRZ1

891

P23471
SAFYFVMKFLNLTSE

ENTPD1

361

P49961
LVLSSVSDYFAAMFT

KLHL5

236

Q96PQ7
KEYTIGNAMTVFFSI

ABCB4

326

P21439
GILSMVFYTDSAIAK

NRP1

241

O14786
SFTTEYTVAVPKSMF

FA2H

201

Q7L5A8
SITFLVEAFDIYGTM

PCDH15

891

Q96QU1
FVVSESFILSAMAYD

OR8B12

106

Q8NGG6
YDFGMRAVKTVISAA

DNAH1

1751

Q9P2D7
VVLASVSPYFKAMFT

KLHL28

51

Q9NXS3
NLKDFFGAYTMDVIT

CYP3A43

171

Q9HB55
TKAYTSQFISLVMFG

GFPT2

476

O94808
MYTSLKSTFVAFADG

LINC02876

1

F2Z3M2
VFSIEAAMKIIAYGF

CACNA1S

96

Q13698
FFYVDITTGALMTAR

CDH20

436

Q9HBT6
GFYSSMFFITLMSVD

CCR8

116

P51685
VSNYIFTAIFVGEMT

CACNA1I

1206

Q9P0X4
YFSDIVGFTTISAMS

GUCY2F

886

P51841
VFSFTMVGKTFTYLL

CYP51A1

101

Q16850
KVSDGKFYSTSMVTI

FAT3

1956

Q8TDW7
IFGADFTKYAIMLFT

GIMAP8

551

Q8ND71
TEKKVFTYFMVTTAA

GJB4

181

Q9NTQ9
TVGYTTAFGAMFAKT

GABBR2

561

O75899
SFVIQMDFSADGKYI

EML6

1816

Q6ZMW3
MDYVASTASIFSVFI

HRH1

106

P35367
MAQSIIFIFAGYETT

CYP3A7

296

P24462
FTTGVVYDTFMLKHQ

HDAC5

681

Q9UQL6
MAFIAKSFYDLSAIS

GPX2

1

P18283
RTYSVSFPMFSKIAV

GPX7

106

Q96SL4
VMGKAFSEAAFTTAY

SLC22A7

436

Q9Y694
STYAKLAAVAVFFIM

SEC22B

191

O75396
MASALSYVSKFKSFV

SLC13A5

1

Q86YT5
GITSAFSMLYVFTAE

SLC22A4

436

Q9H015
KFGVTAAFSMVYVYT

SLC22A5

436

O76082
AMLFSAGTFLYVATV

SLC39A9

246

Q9NUM3
GAFVYGSMSFLDKVA

MFSD12

401

Q6NUT3
ISEYIATKIGAFCMF

MSH2

766

P43246
MSDSQLYEAFTFLKG

CRMP1

176

Q14194
LLAMAGSSDKYFFVE

COL6A6

956

A6NMZ7
DAFYGIVNFLMTIAS

OR13A1

221

Q8NGR1
DKMIAVFYTVGTSFL

OR4C16

266

Q8NGL9
EKMSSAAGVYIFIQS

SLC16A6

416

O15403
VASFSKGYTSIFNME

STRN

631

O43815
KDMIGTAFSLAIVSY

SLC26A9

331

Q7LBE3
VFASIYSMTAVAFDR

TACR1

116

P25103
VGMFLADLIETYFVS

SCN9A

1591

Q15858
FVFVVASDGKIMYIS

SIM2

91

Q14190
FSKVAVGPNTVMSFY

SETD7

231

Q8WTS6
FTIHAYVGFTMDKLV

SIN3B

876

O75182
AESFSVMYTPFATKI

SPATA16

321

Q9BXB7
DTFLNSTLIYFMTGV

OR7D2

191

Q96RA2
LVGKGFTFMYEAAAT

PKHD1

1286

P08F94
FIGEISMYFIKSTRE

PLPPR1

86

Q8TBJ4
RSAAFVIAYIMETFG

STYX

126

Q8WUJ0
KGMFDFVVVLTYANS

SSTR2

291

P30874
IIGFTLGSLFSKMYV

SLCO1B1

221

Q9Y6L6
MKTEEAIIYSYGFAT

SPTLC1

156

O15269
FSMGFIDSIIAKYLA

ABCD3

311

P28288
FFLAIMTDGSIIYVS

CLOCK

121

O15516
VTVEMQKFLGSYFIT

ATP11A

366

P98196
SLYVTVEMQKFLGSF

ATP11B

356

Q9Y2G3
SMFVECGKKYFSTET

COL24A1

176

Q17RW2
SVIAEAVFYTDFMGQ

SLC45A4

521

Q5BKX6
GKYSTTFFMVTFAAL

XPR1

481

Q9UBH6
TDNSKYFEFTVMGRL

THBS4

81

P35443
TGTFVLYKSMSRDFE

VWDE

446

Q8N2E2
GVKDLATVFFYMLVA

TRAM1L1

76

Q8N609
KTCMILVFLSSIFGY

TRPA1

771

O75762
YITGKEVFSFKMVSY

VPS13A

1116

Q96RL7
EEFVSFMTSGLSYIL

NME8

211

Q8N427
GMTKTFAIFFVVFQE

SLC16A4

36

O15374
SLFLYIFTKISVDMF

SLC5A2

146

P31639
IMISTYEFGKSFFQR

SLC25A39

336

Q9BZJ4
KEFSSAIDIMYNGSF

TBC1D8B

881

Q0IIM8
FSHLKEYVASMVFSL

TRPV1

531

Q8NER1
SGVALTLSFVFMYAK

SLCO4C1

461

Q6ZQN7
DSFLEKFMVGEVSYG

SULT1A1

156

P50225
TYKSITGDMAITFVS

SUFU

396

Q9UMX1
FLGFMSFVTTTFVIE

TMEM104

51

Q8NE00
KTFSVAYVLVGAGVM

TMEM51

61

Q9NW97
ASKIMTFCFKVYGAT

NF1

1281

P21359
MTSGSVFFYILIFGK

RXFP1

1

Q9HBX9
AKVGMDSTTVNYFAL

SNX27

306

Q96L92
TDMFYTLTGKSGEIF

STAB2

451

Q8WWQ8
GTKETAFIYAVMAAG

WNT16

116

Q9UBV4
AAFIDIFTSNTYVMV

RRAGB

321

Q5VZM2
FSKISGVLTFMTSFY

TAAR1

186

Q96RJ0
TMIGFSKVTNYIFDS

TBC1D15

246

Q8TC07
KSFMFPSAVAVVDEY

ZBED6

856

P86452
FSMLKAALSGSYVNF

XPO7

836

Q9UIA9
IQSSGKVMYFSSLFP

SLC6A17

246

Q9H1V8
SGKVYMIFFVVVSFL

SCN7A

366

Q01118
NSLVSTFTMEKRGFY

PLEKHA1

331

Q9HB21
KMTALVTYRSFKTFF

ZYG11A

661

Q6WRX3
RFAMFTSTIFAVVGF

TM4SF4

86

P48230
AKGFRENFESMYTSV

TBX21

321

Q9UL17
GFKFDMRVYVLITSC

TTLL13

241

A6NNM8
TVMFAFSGTYTLLFV

SLC18A1

181

P54219
FGDKIARATVYFVAM

SLC8A1

71

P32418