| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 4.99e-11 | 26 | 21 | 5 | GO:0005248 | |
| GeneOntologyMolecularFunction | sodium channel activity | 1.94e-09 | 52 | 21 | 5 | GO:0005272 | |
| GeneOntologyMolecularFunction | transmembrane transporter activity | SLC51A SCN10A CACNA1S ABCG5 SCN1A SLC22A12 SCN3A SCN4A SCN5A SLC39A10 TMC2 | 5.97e-09 | 1180 | 21 | 11 | GO:0022857 |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | 1.27e-08 | 465 | 21 | 8 | GO:0046873 | |
| GeneOntologyMolecularFunction | transporter activity | SLC51A SCN10A CACNA1S ABCG5 SCN1A SLC22A12 SCN3A SCN4A SCN5A SLC39A10 TMC2 | 1.50e-08 | 1289 | 21 | 11 | GO:0005215 |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | 3.92e-08 | 343 | 21 | 7 | GO:0005261 | |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | 1.28e-07 | 627 | 21 | 8 | GO:0022890 | |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | 1.99e-07 | 664 | 21 | 8 | GO:0008324 | |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | 2.85e-07 | 459 | 21 | 7 | GO:0005216 | |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | 5.45e-07 | 758 | 21 | 8 | GO:0015318 | |
| GeneOntologyMolecularFunction | channel activity | 7.05e-07 | 525 | 21 | 7 | GO:0015267 | |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | 7.14e-07 | 526 | 21 | 7 | GO:0022803 | |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | 7.67e-07 | 793 | 21 | 8 | GO:0015075 | |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | 7.91e-07 | 171 | 21 | 5 | GO:0015081 | |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity involved in cardiac muscle cell action potential | 1.58e-05 | 6 | 21 | 2 | GO:0086006 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | 3.54e-05 | 182 | 21 | 4 | GO:0005244 | |
| GeneOntologyMolecularFunction | voltage-gated channel activity | 3.69e-05 | 184 | 21 | 4 | GO:0022832 | |
| GeneOntologyMolecularFunction | sodium ion binding | 9.51e-05 | 14 | 21 | 2 | GO:0031402 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | 1.42e-04 | 17 | 21 | 2 | GO:0099508 | |
| GeneOntologyMolecularFunction | alkali metal ion binding | 3.37e-04 | 26 | 21 | 2 | GO:0031420 | |
| GeneOntologyMolecularFunction | gated channel activity | 3.67e-04 | 334 | 21 | 4 | GO:0022836 | |
| GeneOntologyMolecularFunction | transmembrane transporter binding | 7.45e-04 | 172 | 21 | 3 | GO:0044325 | |
| GeneOntologyMolecularFunction | voltage-gated calcium channel activity | 1.06e-03 | 46 | 21 | 2 | GO:0005245 | |
| GeneOntologyMolecularFunction | calmodulin binding | 1.72e-03 | 230 | 21 | 3 | GO:0005516 | |
| GeneOntologyMolecularFunction | calcium channel activity | 8.03e-03 | 129 | 21 | 2 | GO:0005262 | |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | 1.09e-02 | 151 | 21 | 2 | GO:0015085 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic cation channel activity | 1.10e-02 | 152 | 21 | 2 | GO:0022843 | |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | 1.25e-02 | 884 | 21 | 4 | GO:0004930 | |
| GeneOntologyMolecularFunction | lipid transporter activity | 1.78e-02 | 196 | 21 | 2 | GO:0005319 | |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 2.42e-10 | 36 | 21 | 5 | GO:0086010 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential involved in contraction | 4.08e-09 | 62 | 21 | 5 | GO:0086002 | |
| GeneOntologyBiologicalProcess | neuronal action potential | 4.43e-09 | 63 | 21 | 5 | GO:0019228 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential | 2.29e-08 | 87 | 21 | 5 | GO:0086001 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell contraction | 3.21e-08 | 93 | 21 | 5 | GO:0086003 | |
| GeneOntologyBiologicalProcess | striated muscle contraction | 6.02e-08 | 217 | 21 | 6 | GO:0006941 | |
| GeneOntologyBiologicalProcess | transmission of nerve impulse | 8.19e-08 | 112 | 21 | 5 | GO:0019226 | |
| GeneOntologyBiologicalProcess | membrane depolarization | 1.21e-07 | 121 | 21 | 5 | GO:0051899 | |
| GeneOntologyBiologicalProcess | actin-mediated cell contraction | 1.54e-07 | 127 | 21 | 5 | GO:0070252 | |
| GeneOntologyBiologicalProcess | metal ion transport | 2.48e-07 | 1000 | 21 | 9 | GO:0030001 | |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | 2.86e-07 | 1017 | 21 | 9 | GO:0098660 | |
| GeneOntologyBiologicalProcess | monoatomic ion transport | SCN10A CACNA1S CASR SCN1A SLC22A12 SCN3A SCN4A SCN5A SLC39A10 TMC2 | 2.98e-07 | 1374 | 21 | 10 | GO:0006811 |
| GeneOntologyBiologicalProcess | actin filament-based movement | 3.89e-07 | 153 | 21 | 5 | GO:0030048 | |
| GeneOntologyBiologicalProcess | cardiac muscle contraction | 6.00e-07 | 167 | 21 | 5 | GO:0060048 | |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | 6.22e-07 | 1115 | 21 | 9 | GO:0034220 | |
| GeneOntologyBiologicalProcess | monoatomic cation transport | 8.48e-07 | 1157 | 21 | 9 | GO:0006812 | |
| GeneOntologyBiologicalProcess | action potential | 1.50e-06 | 201 | 21 | 5 | GO:0001508 | |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | 1.77e-06 | 208 | 21 | 5 | GO:0035725 | |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | 1.87e-06 | 922 | 21 | 8 | GO:0098662 | |
| GeneOntologyBiologicalProcess | muscle contraction | 2.17e-06 | 400 | 21 | 6 | GO:0006936 | |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | 2.20e-06 | 942 | 21 | 8 | GO:0098655 | |
| GeneOntologyBiologicalProcess | regulation of presynaptic membrane potential | 4.43e-06 | 32 | 21 | 3 | GO:0099505 | |
| GeneOntologyBiologicalProcess | sodium ion transport | 6.94e-06 | 275 | 21 | 5 | GO:0006814 | |
| GeneOntologyBiologicalProcess | heart contraction | 1.02e-05 | 298 | 21 | 5 | GO:0060047 | |
| GeneOntologyBiologicalProcess | heart process | 1.22e-05 | 309 | 21 | 5 | GO:0003015 | |
| GeneOntologyBiologicalProcess | muscle system process | 1.31e-05 | 547 | 21 | 6 | GO:0003012 | |
| GeneOntologyBiologicalProcess | regulation of membrane potential | 1.48e-05 | 559 | 21 | 6 | GO:0042391 | |
| GeneOntologyBiologicalProcess | bundle of His cell action potential | 2.07e-05 | 7 | 21 | 2 | GO:0086043 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte signaling | 2.07e-05 | 7 | 21 | 2 | GO:0086028 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus involved in sensory perception | 2.57e-05 | 57 | 21 | 3 | GO:0050974 | |
| GeneOntologyBiologicalProcess | blood circulation | 3.41e-05 | 648 | 21 | 6 | GO:0008015 | |
| GeneOntologyBiologicalProcess | regulation of atrial cardiac muscle cell membrane depolarization | 4.42e-05 | 10 | 21 | 2 | GO:0060371 | |
| GeneOntologyBiologicalProcess | regulation of muscle contraction | 4.69e-05 | 202 | 21 | 4 | GO:0006937 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus | 5.86e-05 | 75 | 21 | 3 | GO:0050982 | |
| GeneOntologyBiologicalProcess | detection of stimulus | 6.23e-05 | 722 | 21 | 6 | GO:0051606 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell signaling | 6.48e-05 | 12 | 21 | 2 | GO:0086027 | |
| GeneOntologyBiologicalProcess | AV node cell action potential | 6.48e-05 | 12 | 21 | 2 | GO:0086016 | |
| GeneOntologyBiologicalProcess | circulatory system process | 6.78e-05 | 733 | 21 | 6 | GO:0003013 | |
| GeneOntologyBiologicalProcess | regulation of system process | 6.83e-05 | 734 | 21 | 6 | GO:0044057 | |
| GeneOntologyBiologicalProcess | bile acid secretion | 7.65e-05 | 13 | 21 | 2 | GO:0032782 | |
| GeneOntologyBiologicalProcess | bundle of His cell to Purkinje myocyte communication | 1.03e-04 | 15 | 21 | 2 | GO:0086069 | |
| GeneOntologyBiologicalProcess | AV node cell to bundle of His cell communication | 1.03e-04 | 15 | 21 | 2 | GO:0086067 | |
| GeneOntologyBiologicalProcess | regulation of striated muscle contraction | 1.88e-04 | 111 | 21 | 3 | GO:0006942 | |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | 2.46e-04 | 582 | 21 | 5 | GO:0050906 | |
| GeneOntologyBiologicalProcess | regulation of muscle system process | 2.66e-04 | 317 | 21 | 4 | GO:0090257 | |
| GeneOntologyBiologicalProcess | inorganic cation import across plasma membrane | 3.88e-04 | 142 | 21 | 3 | GO:0098659 | |
| GeneOntologyBiologicalProcess | inorganic ion import across plasma membrane | 3.88e-04 | 142 | 21 | 3 | GO:0099587 | |
| GeneOntologyBiologicalProcess | behavioral response to pain | 4.81e-04 | 32 | 21 | 2 | GO:0048266 | |
| GeneOntologyBiologicalProcess | cell-cell signaling involved in cardiac conduction | 5.43e-04 | 34 | 21 | 2 | GO:0086019 | |
| GeneOntologyBiologicalProcess | detection of external stimulus | 6.90e-04 | 173 | 21 | 3 | GO:0009581 | |
| GeneOntologyBiologicalProcess | detection of abiotic stimulus | 7.14e-04 | 175 | 21 | 3 | GO:0009582 | |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception of pain | 8.69e-04 | 43 | 21 | 2 | GO:0062149 | |
| GeneOntologyBiologicalProcess | response to pain | 1.22e-03 | 51 | 21 | 2 | GO:0048265 | |
| GeneOntologyBiologicalProcess | neuromuscular process | 1.47e-03 | 225 | 21 | 3 | GO:0050905 | |
| GeneOntologyBiologicalProcess | acid secretion | 1.52e-03 | 57 | 21 | 2 | GO:0046717 | |
| GeneOntologyBiologicalProcess | import across plasma membrane | 1.57e-03 | 230 | 21 | 3 | GO:0098739 | |
| GeneOntologyBiologicalProcess | cell communication involved in cardiac conduction | 1.63e-03 | 59 | 21 | 2 | GO:0086065 | |
| GeneOntologyBiologicalProcess | organic anion transport | 1.64e-03 | 515 | 21 | 4 | GO:0015711 | |
| GeneOntologyBiologicalProcess | sensory perception of mechanical stimulus | 1.73e-03 | 238 | 21 | 3 | GO:0050954 | |
| GeneOntologyBiologicalProcess | regulation of membrane depolarization | 1.74e-03 | 61 | 21 | 2 | GO:0003254 | |
| GeneOntologyBiologicalProcess | response to abiotic stimulus | 1.87e-03 | 1361 | 21 | 6 | GO:0009628 | |
| GeneOntologyBiologicalProcess | actin filament-based process | 1.88e-03 | 912 | 21 | 5 | GO:0030029 | |
| GeneOntologyBiologicalProcess | response to mechanical stimulus | 1.92e-03 | 247 | 21 | 3 | GO:0009612 | |
| GeneOntologyBiologicalProcess | regulation of monoatomic ion transport | 2.48e-03 | 577 | 21 | 4 | GO:0043269 | |
| GeneOntologyBiologicalProcess | cellular homeostasis | 2.59e-03 | 981 | 21 | 5 | GO:0019725 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic cation homeostasis | 3.05e-03 | 611 | 21 | 4 | GO:0030003 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic ion homeostasis | 3.26e-03 | 622 | 21 | 4 | GO:0006873 | |
| GeneOntologyBiologicalProcess | regulation of cardiac muscle contraction | 3.67e-03 | 89 | 21 | 2 | GO:0055117 | |
| GeneOntologyBiologicalProcess | sensory perception | 3.81e-03 | 1072 | 21 | 5 | GO:0007600 | |
| GeneOntologyBiologicalProcess | regulation of blood circulation | 4.21e-03 | 326 | 21 | 3 | GO:1903522 | |
| GeneOntologyBiologicalProcess | calcium ion import | 4.42e-03 | 98 | 21 | 2 | GO:0070509 | |
| GeneOntologyBiologicalProcess | cardiac conduction | 4.60e-03 | 100 | 21 | 2 | GO:0061337 | |
| GeneOntologyBiologicalProcess | sensory perception of pain | 5.06e-03 | 105 | 21 | 2 | GO:0019233 | |
| GeneOntologyBiologicalProcess | monoatomic cation homeostasis | 5.09e-03 | 705 | 21 | 4 | GO:0055080 | |
| GeneOntologyBiologicalProcess | odontogenesis of dentin-containing tooth | 5.25e-03 | 107 | 21 | 2 | GO:0042475 | |
| GeneOntologyBiologicalProcess | monoatomic ion homeostasis | 5.41e-03 | 717 | 21 | 4 | GO:0050801 | |
| GeneOntologyBiologicalProcess | multicellular organismal response to stress | 7.21e-03 | 126 | 21 | 2 | GO:0033555 | |
| GeneOntologyBiologicalProcess | chemical homeostasis | 7.28e-03 | 1249 | 21 | 5 | GO:0048878 | |
| GeneOntologyBiologicalProcess | regulation of heart rate | 7.54e-03 | 129 | 21 | 2 | GO:0002027 | |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 3.76e-12 | 17 | 21 | 5 | GO:0001518 | |
| GeneOntologyCellularComponent | sodium channel complex | 7.16e-11 | 29 | 21 | 5 | GO:0034706 | |
| GeneOntologyCellularComponent | cation channel complex | 8.92e-08 | 235 | 21 | 6 | GO:0034703 | |
| GeneOntologyCellularComponent | transmembrane transporter complex | 5.06e-07 | 523 | 21 | 7 | GO:1902495 | |
| GeneOntologyCellularComponent | transporter complex | 7.09e-07 | 550 | 21 | 7 | GO:1990351 | |
| GeneOntologyCellularComponent | monoatomic ion channel complex | 1.45e-06 | 378 | 21 | 6 | GO:0034702 | |
| GeneOntologyCellularComponent | plasma membrane protein complex | 7.52e-06 | 785 | 21 | 7 | GO:0098797 | |
| GeneOntologyCellularComponent | T-tubule | 6.58e-05 | 79 | 21 | 3 | GO:0030315 | |
| GeneOntologyCellularComponent | axon | 1.84e-04 | 891 | 21 | 6 | GO:0030424 | |
| GeneOntologyCellularComponent | membrane protein complex | 4.55e-04 | 1498 | 21 | 7 | GO:0098796 | |
| GeneOntologyCellularComponent | I band | 5.89e-04 | 166 | 21 | 3 | GO:0031674 | |
| GeneOntologyCellularComponent | sarcolemma | 8.71e-04 | 190 | 21 | 3 | GO:0042383 | |
| GeneOntologyCellularComponent | apical plasma membrane | 1.27e-03 | 487 | 21 | 4 | GO:0016324 | |
| GeneOntologyCellularComponent | sarcomere | 1.89e-03 | 249 | 21 | 3 | GO:0030017 | |
| GeneOntologyCellularComponent | intercalated disc | 2.10e-03 | 68 | 21 | 2 | GO:0014704 | |
| GeneOntologyCellularComponent | myofibril | 2.46e-03 | 273 | 21 | 3 | GO:0030016 | |
| GeneOntologyCellularComponent | apical part of cell | 2.60e-03 | 592 | 21 | 4 | GO:0045177 | |
| GeneOntologyCellularComponent | contractile muscle fiber | 2.92e-03 | 290 | 21 | 3 | GO:0043292 | |
| GeneOntologyCellularComponent | cell-cell contact zone | 3.97e-03 | 94 | 21 | 2 | GO:0044291 | |
| GeneOntologyCellularComponent | sarcoplasm | 5.79e-03 | 114 | 21 | 2 | GO:0016528 | |
| GeneOntologyCellularComponent | Z disc | 9.95e-03 | 151 | 21 | 2 | GO:0030018 | |
| HumanPheno | Hypokalemia | 5.75e-07 | 79 | 12 | 5 | HP:0002900 | |
| HumanPheno | Abnormal blood potassium concentration | 3.44e-06 | 113 | 12 | 5 | HP:0011042 | |
| HumanPheno | Abnormal blood monovalent inorganic cation concentration | 1.58e-05 | 154 | 12 | 5 | HP:0010930 | |
| HumanPheno | Reduced systolic function | 1.72e-05 | 23 | 12 | 3 | HP:0006673 | |
| HumanPheno | Malignant hyperthermia | 2.52e-05 | 26 | 12 | 3 | HP:0002047 | |
| HumanPheno | Episodic hypokalemia | 7.59e-05 | 6 | 12 | 2 | HP:0012726 | |
| HumanPheno | Episodic flaccid weakness | 1.06e-04 | 7 | 12 | 2 | HP:0003752 | |
| HumanPheno | Abnormal blood cation concentration | 1.41e-04 | 401 | 12 | 6 | HP:0010929 | |
| HumanPheno | Late-onset proximal muscle weakness | 1.41e-04 | 8 | 12 | 2 | HP:0003694 | |
| HumanPheno | Sudden death | 1.76e-04 | 131 | 12 | 4 | HP:0001699 | |
| HumanPheno | Periodic hypokalemic paresis | 1.81e-04 | 9 | 12 | 2 | HP:0008153 | |
| HumanPheno | Adrenocortical adenoma | 1.81e-04 | 9 | 12 | 2 | HP:0008256 | |
| HumanPheno | Respiratory paralysis | 1.81e-04 | 9 | 12 | 2 | HP:0002203 | |
| HumanPheno | Postprandial hyperglycemia | 1.81e-04 | 9 | 12 | 2 | HP:0011998 | |
| HumanPheno | Apneic episodes in infancy | 2.27e-04 | 10 | 12 | 2 | HP:0005949 | |
| HumanPheno | Impaired myocardial contractility | 2.27e-04 | 10 | 12 | 2 | HP:0006670 | |
| HumanPheno | Prolonged QT interval | 2.32e-04 | 54 | 12 | 3 | HP:0001657 | |
| HumanPheno | Abnormal blood ion concentration | 2.52e-04 | 445 | 12 | 6 | HP:0003111 | |
| HumanPheno | Paresthesia | 2.54e-04 | 144 | 12 | 4 | HP:0003401 | |
| HumanPheno | Periodic paralysis | 2.77e-04 | 11 | 12 | 2 | HP:0003768 | |
| HumanPheno | Exercise-induced muscle fatigue | 3.31e-04 | 12 | 12 | 2 | HP:0009020 | |
| HumanPheno | Ventricular fibrillation | 3.66e-04 | 63 | 12 | 3 | HP:0001663 | |
| HumanPheno | Abnormal QT interval | 3.84e-04 | 64 | 12 | 3 | HP:0031547 | |
| HumanPheno | Postexertional symptom exacerbation | 4.56e-04 | 14 | 12 | 2 | HP:0030973 | |
| HumanPheno | Ventricular tachycardia | 4.80e-04 | 69 | 12 | 3 | HP:0004756 | |
| HumanPheno | Muscle flaccidity | 5.25e-04 | 15 | 12 | 2 | HP:0010547 | |
| HumanPheno | Second degree atrioventricular block | 5.25e-04 | 15 | 12 | 2 | HP:0011706 | |
| HumanPheno | Atrioventricular valve regurgitation | 8.25e-04 | 196 | 12 | 4 | HP:0034376 | |
| HumanPheno | Arrhythmia | 8.29e-04 | 553 | 12 | 6 | HP:0011675 | |
| HumanPheno | Increased muscle fatiguability | 8.51e-04 | 19 | 12 | 2 | HP:0003750 | |
| HumanPheno | Abnormal cardiac exercise stress test | 8.51e-04 | 19 | 12 | 2 | HP:0500018 | |
| HumanPheno | Hyperphosphatemia | 1.04e-03 | 21 | 12 | 2 | HP:0002905 | |
| HumanPheno | Intermediate young adult onset | 1.04e-03 | 21 | 12 | 2 | HP:0025709 | |
| HumanPheno | Abnormality of cardiovascular system electrophysiology | 1.07e-03 | 580 | 12 | 6 | HP:0030956 | |
| HumanPheno | Trifascicular block | 1.14e-03 | 22 | 12 | 2 | HP:0011715 | |
| HumanPheno | Atrioventricular block | 1.15e-03 | 93 | 12 | 3 | HP:0001678 | |
| HumanPheno | Heart block | 1.15e-03 | 93 | 12 | 3 | HP:0001668 | |
| HumanPheno | Abnormal atrioventricular valve physiology | 1.17e-03 | 215 | 12 | 4 | HP:0031650 | |
| HumanPheno | Pain | 1.25e-03 | 846 | 12 | 7 | HP:0012531 | |
| HumanPheno | Increased intramyocellular lipid droplets | 1.25e-03 | 23 | 12 | 2 | HP:0012240 | |
| HumanPheno | Vertical nystagmus | 1.25e-03 | 23 | 12 | 2 | HP:0010544 | |
| HumanPheno | Bradycardia | 1.34e-03 | 98 | 12 | 3 | HP:0001662 | |
| HumanPheno | Phenotypic variability | 1.36e-03 | 224 | 12 | 4 | HP:0003812 | |
| HumanPheno | ST segment elevation | 1.48e-03 | 25 | 12 | 2 | HP:0012251 | |
| HumanPheno | Torsade de pointes | 1.48e-03 | 25 | 12 | 2 | HP:0001664 | |
| HumanPheno | Abnormal PR interval | 1.48e-03 | 25 | 12 | 2 | HP:0031593 | |
| HumanPheno | Paroxysmal ventricular tachycardia | 1.73e-03 | 27 | 12 | 2 | HP:0004751 | |
| HumanPheno | Simple febrile seizure | 1.73e-03 | 27 | 12 | 2 | HP:0011171 | |
| HumanPheno | Abnormality of masticatory muscle | 1.73e-03 | 27 | 12 | 2 | HP:0410011 | |
| HumanPheno | Neoplasm of the adrenal cortex | 1.86e-03 | 28 | 12 | 2 | HP:0100641 | |
| HumanPheno | Sudden cardiac death | 1.97e-03 | 112 | 12 | 3 | HP:0001645 | |
| HumanPheno | Abnormal glomerular filtration rate | 1.99e-03 | 29 | 12 | 2 | HP:0012212 | |
| HumanPheno | Decreased glomerular filtration rate | 1.99e-03 | 29 | 12 | 2 | HP:0012213 | |
| HumanPheno | Prolonged QTc interval | 1.99e-03 | 29 | 12 | 2 | HP:0005184 | |
| HumanPheno | Premature ventricular contraction | 1.99e-03 | 29 | 12 | 2 | HP:0006682 | |
| HumanPheno | Sick sinus syndrome | 1.99e-03 | 29 | 12 | 2 | HP:0011704 | |
| HumanPheno | Sinus bradycardia | 2.13e-03 | 30 | 12 | 2 | HP:0001688 | |
| HumanPheno | Tented upper lip vermilion | 2.18e-03 | 116 | 12 | 3 | HP:0010804 | |
| HumanPheno | Hypomagnesemia | 2.28e-03 | 31 | 12 | 2 | HP:0002917 | |
| HumanPheno | Abnormality of jaw muscles | 2.28e-03 | 31 | 12 | 2 | HP:0045037 | |
| HumanPheno | Abnormal exteroceptive sensation | 2.34e-03 | 259 | 12 | 4 | HP:0033747 | |
| HumanPheno | Supraventricular tachycardia | 2.40e-03 | 120 | 12 | 3 | HP:0004755 | |
| HumanPheno | Fatigable weakness | 2.46e-03 | 121 | 12 | 3 | HP:0003473 | |
| HumanPheno | Abnormality of cardiac conduction | 2.52e-03 | 452 | 12 | 5 | HP:0001665 | |
| HumanPheno | Abnormal synaptic transmission at the neuromuscular junction | 2.52e-03 | 122 | 12 | 3 | HP:0003398 | |
| HumanPheno | Abnormal peripheral nervous system synaptic transmission | 2.52e-03 | 122 | 12 | 3 | HP:0030191 | |
| HumanPheno | Abnormal synaptic transmission | 2.52e-03 | 122 | 12 | 3 | HP:0012535 | |
| HumanPheno | Myotonia | 2.74e-03 | 34 | 12 | 2 | HP:0002486 | |
| HumanPheno | Abnormal magnesium concentration | 2.74e-03 | 34 | 12 | 2 | HP:0004921 | |
| HumanPheno | Focal impaired awareness seizure | 2.76e-03 | 126 | 12 | 3 | HP:0002384 | |
| HumanPheno | Abnormal urinary electrolyte concentration | 2.76e-03 | 126 | 12 | 3 | HP:0012591 | |
| HumanPheno | Constitutional symptom | 2.79e-03 | 1276 | 12 | 8 | HP:0025142 | |
| MousePheno | ventricular fibrillation | 3.28e-05 | 7 | 18 | 2 | MP:0006110 | |
| MousePheno | abnormal postural reflex | 1.13e-04 | 203 | 18 | 4 | MP:0002980 | |
| MousePheno | impaired ability to fire action potentials | 1.21e-04 | 13 | 18 | 2 | MP:0002578 | |
| MousePheno | fibrillation | 1.41e-04 | 14 | 18 | 2 | MP:0006109 | |
| MousePheno | sinus bradycardia | 1.41e-04 | 14 | 18 | 2 | MP:0010637 | |
| MousePheno | abnormal posture | 2.25e-04 | 243 | 18 | 4 | MP:0001504 | |
| MousePheno | akinesia | 3.24e-04 | 21 | 18 | 2 | MP:0002690 | |
| MousePheno | ventricular premature beat | 4.62e-04 | 25 | 18 | 2 | MP:0009732 | |
| MousePheno | apnea | 5.39e-04 | 27 | 18 | 2 | MP:0001957 | |
| MousePheno | abnormal action potential | 6.19e-04 | 133 | 18 | 3 | MP:0005402 | |
| MousePheno | abnormal muscle electrophysiology | 7.59e-04 | 32 | 18 | 2 | MP:0004145 | |
| Domain | Na_channel_asu | 2.70e-13 | 10 | 21 | 5 | IPR001696 | |
| Domain | Na_trans_assoc | 2.70e-13 | 10 | 21 | 5 | IPR010526 | |
| Domain | Na_trans_assoc | 2.70e-13 | 10 | 21 | 5 | PF06512 | |
| Domain | Channel_four-helix_dom | 3.23e-11 | 57 | 21 | 6 | IPR027359 | |
| Domain | - | 3.23e-11 | 57 | 21 | 6 | 1.20.120.350 | |
| Domain | Ion_trans_dom | 2.28e-09 | 114 | 21 | 6 | IPR005821 | |
| Domain | Ion_trans | 2.28e-09 | 114 | 21 | 6 | PF00520 | |
| Domain | Na_trans_cytopl | 2.44e-08 | 6 | 21 | 3 | PF11933 | |
| Domain | Na_trans_cytopl | 2.44e-08 | 6 | 21 | 3 | IPR024583 | |
| Domain | IQ_motif_EF-hand-BS | 4.45e-08 | 90 | 21 | 5 | IPR000048 | |
| Domain | IQ | 5.25e-08 | 93 | 21 | 5 | PS50096 | |
| Domain | IQ | 1.09e-06 | 71 | 21 | 4 | PF00612 | |
| Domain | IQ | 1.86e-06 | 81 | 21 | 4 | SM00015 | |
| Domain | EF-hand-dom_pair | 3.89e-03 | 287 | 21 | 3 | IPR011992 | |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 3.08e-10 | 31 | 18 | 5 | M877 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 3.65e-10 | 32 | 18 | 5 | M27455 | |
| Pathway | REACTOME_L1CAM_INTERACTIONS | 3.36e-07 | 121 | 18 | 5 | M872 | |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 4.80e-07 | 130 | 18 | 5 | M27454 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 4.34e-06 | 203 | 18 | 5 | M5485 | |
| Pathway | REACTOME_NERVOUS_SYSTEM_DEVELOPMENT | 5.47e-05 | 575 | 18 | 6 | M29853 | |
| Pathway | WP_ADHD_AND_AUTISM_ASD_PATHWAYS | 7.54e-05 | 367 | 18 | 5 | M48346 | |
| Pathway | WP_GPCRS_OTHER | 2.32e-04 | 96 | 18 | 3 | MM15939 | |
| Pathway | WP_DRAVET_SYNDROME | 5.71e-04 | 28 | 18 | 2 | M45519 | |
| Pathway | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | 9.99e-04 | 37 | 18 | 2 | MM15067 | |
| Pathway | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | 1.11e-03 | 39 | 18 | 2 | M793 | |
| Pathway | REACTOME_SENSORY_PERCEPTION_OF_TASTE | 1.61e-03 | 47 | 18 | 2 | M42524 | |
| Pathway | WP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL | 3.84e-03 | 73 | 18 | 2 | MM16641 | |
| Pubmed | 6.04e-15 | 9 | 21 | 5 | 16382098 | ||
| Pubmed | 1.23e-11 | 9 | 21 | 4 | 15746173 | ||
| Pubmed | 7.00e-11 | 13 | 21 | 4 | 15123669 | ||
| Pubmed | Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. | 1.89e-10 | 139 | 21 | 6 | 16985003 | |
| Pubmed | 1.90e-09 | 5 | 21 | 3 | 17724025 | ||
| Pubmed | A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. | 3.79e-09 | 6 | 21 | 3 | 23652591 | |
| Pubmed | 1.06e-08 | 8 | 21 | 3 | 9412493 | ||
| Pubmed | Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. | 4.16e-08 | 12 | 21 | 3 | 30175250 | |
| Pubmed | A common genetic variant within SCN10A modulates cardiac SCN5A expression. | 3.47e-07 | 2 | 21 | 2 | 24642470 | |
| Pubmed | Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. | 3.47e-07 | 2 | 21 | 2 | 16054936 | |
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 33712547 | ||
| Pubmed | Voltage sensor charge loss accounts for most cases of hypokalemic periodic paralysis. | 3.47e-07 | 2 | 21 | 2 | 19118277 | |
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 11834499 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 35759432 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 27690330 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 15047701 | ||
| Pubmed | Absence of ion channels CACN1AS and SCN4A mutations in thyrotoxic hypokalemic periodic paralysis. | 3.47e-07 | 2 | 21 | 2 | 15072700 | |
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 34608571 | ||
| Pubmed | Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome. | 3.47e-07 | 2 | 21 | 2 | 24998131 | |
| Pubmed | Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome. | 3.47e-07 | 2 | 21 | 2 | 23965409 | |
| Pubmed | Genotype and phenotype analysis of patients with sporadic periodic paralysis. | 3.47e-07 | 2 | 21 | 2 | 21841462 | |
| Pubmed | Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A. | 3.47e-07 | 2 | 21 | 2 | 24990319 | |
| Pubmed | Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif. | 3.47e-07 | 2 | 21 | 2 | 30944319 | |
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 24360055 | ||
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 31292628 | ||
| Pubmed | Mutation analysis of CACNA1S and SCN4A in patients with hypokalemic periodic paralysis. | 3.47e-07 | 2 | 21 | 2 | 26252573 | |
| Pubmed | 3.47e-07 | 2 | 21 | 2 | 32330377 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 20301512 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 12610651 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 33895391 | ||
| Pubmed | Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin. | 1.04e-06 | 3 | 21 | 2 | 15746172 | |
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 23859570 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 19699781 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 14973256 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 18784617 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 17544618 | ||
| Pubmed | Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. | 1.04e-06 | 3 | 21 | 2 | 17052333 | |
| Pubmed | Mutation spectrum and health status in skeletal muscle channelopathies in Japan. | 1.04e-06 | 3 | 21 | 2 | 32660787 | |
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 20038812 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 25998140 | ||
| Pubmed | 1.04e-06 | 3 | 21 | 2 | 27816501 | ||
| Pubmed | Genome-wide association studies of the PR interval in African Americans. | 2.08e-06 | 4 | 21 | 2 | 21347284 | |
| Pubmed | 2.08e-06 | 4 | 21 | 2 | 17537961 | ||
| Pubmed | 2.08e-06 | 4 | 21 | 2 | 35031483 | ||
| Pubmed | 2.08e-06 | 4 | 21 | 2 | 29578003 | ||
| Pubmed | 2.08e-06 | 4 | 21 | 2 | 35801810 | ||
| Pubmed | 2.08e-06 | 4 | 21 | 2 | 22260870 | ||
| Pubmed | Use of recombinant inbred strains for studying genetic determinants of responses to alcohol. | 2.08e-06 | 4 | 21 | 2 | 8974318 | |
| Pubmed | Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins. | 3.47e-06 | 5 | 21 | 2 | 15548568 | |
| Pubmed | 3.47e-06 | 5 | 21 | 2 | 1679748 | ||
| Pubmed | 3.47e-06 | 5 | 21 | 2 | 8812438 | ||
| Pubmed | Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer. | 3.47e-06 | 5 | 21 | 2 | 22706305 | |
| Pubmed | Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. | 3.47e-06 | 5 | 21 | 2 | 23463857 | |
| Pubmed | 3.47e-06 | 5 | 21 | 2 | 23872634 | ||
| Pubmed | Early development of electrical excitability in the mouse enteric nervous system. | 3.47e-06 | 5 | 21 | 2 | 22875929 | |
| Pubmed | 3.47e-06 | 5 | 21 | 2 | 24337656 | ||
| Pubmed | 5.20e-06 | 6 | 21 | 2 | 23711479 | ||
| Pubmed | 7.28e-06 | 7 | 21 | 2 | 23139255 | ||
| Pubmed | 7.28e-06 | 7 | 21 | 2 | 15272007 | ||
| Pubmed | Pain without nociceptors? Nav1.7-independent pain mechanisms. | 7.28e-06 | 7 | 21 | 2 | 24440715 | |
| Pubmed | 9.70e-06 | 8 | 21 | 2 | 25101983 | ||
| Pubmed | Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse. | 1.25e-05 | 9 | 21 | 2 | 8854872 | |
| Pubmed | Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. | 1.25e-05 | 9 | 21 | 2 | 17884088 | |
| Pubmed | 2.28e-05 | 12 | 21 | 2 | 8169823 | ||
| Pubmed | 2.28e-05 | 12 | 21 | 2 | 20062060 | ||
| Pubmed | Several common variants modulate heart rate, PR interval and QRS duration. | 3.15e-05 | 14 | 21 | 2 | 20062063 | |
| Pubmed | Confirmation of quantitative trait loci for alcohol preference in mice. | 3.63e-05 | 15 | 21 | 2 | 9726281 | |
| Pubmed | 4.15e-05 | 16 | 21 | 2 | 25035420 | ||
| Pubmed | Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. | 4.70e-05 | 17 | 21 | 2 | 21076409 | |
| Pubmed | 4.70e-05 | 17 | 21 | 2 | 24850809 | ||
| Pubmed | An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo. | 5.28e-05 | 18 | 21 | 2 | 31666509 | |
| Pubmed | Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit. | 7.24e-05 | 21 | 21 | 2 | 28302382 | |
| Pubmed | 8.72e-05 | 23 | 21 | 2 | 16637659 | ||
| Pubmed | 9.51e-05 | 24 | 21 | 2 | 20301690 | ||
| Pubmed | 1.50e-04 | 30 | 21 | 2 | 39366945 | ||
| Pubmed | ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. | 5.43e-04 | 57 | 21 | 2 | 23788249 | |
| Pubmed | 5.43e-04 | 57 | 21 | 2 | 24952745 | ||
| Interaction | SCN10A interactions | 1.60e-07 | 11 | 21 | 3 | int:SCN10A | |
| Interaction | SCN11A interactions | 4.40e-07 | 15 | 21 | 3 | int:SCN11A | |
| Interaction | CACNA1D interactions | 1.95e-06 | 24 | 21 | 3 | int:CACNA1D | |
| Interaction | SCN1A interactions | 3.50e-06 | 29 | 21 | 3 | int:SCN1A | |
| Interaction | SCN5A interactions | 1.54e-05 | 47 | 21 | 3 | int:SCN5A | |
| Interaction | NALCN interactions | 9.34e-05 | 14 | 21 | 2 | int:NALCN | |
| Interaction | SNTA1 interactions | 1.71e-04 | 105 | 21 | 3 | int:SNTA1 | |
| Interaction | TSPAN15 interactions | 1.71e-04 | 276 | 21 | 4 | int:TSPAN15 | |
| Interaction | SCN8A interactions | 1.94e-04 | 20 | 21 | 2 | int:SCN8A | |
| Interaction | SCN9A interactions | 2.15e-04 | 21 | 21 | 2 | int:SCN9A | |
| Interaction | CACNA1A interactions | 2.72e-04 | 123 | 21 | 3 | int:CACNA1A | |
| Interaction | NEDD4L interactions | 3.02e-04 | 320 | 21 | 4 | int:NEDD4L | |
| Interaction | CACNA1B interactions | 6.74e-04 | 37 | 21 | 2 | int:CACNA1B | |
| Interaction | YIPF3 interactions | 9.10e-04 | 186 | 21 | 3 | int:YIPF3 | |
| Interaction | WNT7A interactions | 1.13e-03 | 48 | 21 | 2 | int:WNT7A | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr2q24 | 1.54e-03 | 127 | 21 | 2 | chr2q24 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr3p22 | 3.19e-03 | 184 | 21 | 2 | chr3p22 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 6.69e-14 | 9 | 18 | 5 | 1203 | |
| GeneFamily | Solute carriers | 6.62e-03 | 395 | 18 | 3 | 752 | |
| ToppCell | TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-2|TCGA-Cervix / Sample_Type by Project: Shred V9 | 2.32e-05 | 119 | 21 | 3 | d21877baa088440a1e1902bbeb667b977475437a | |
| ToppCell | facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.18e-05 | 145 | 21 | 3 | 96712c68ab759d7ade0d912581a1a7c25dc6def8 | |
| ToppCell | 10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue | 5.29e-05 | 157 | 21 | 3 | c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a | |
| ToppCell | facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.39e-05 | 158 | 21 | 3 | f296ca24fdedc33f1d24b79e7660763114ce7fa3 | |
| ToppCell | facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.39e-05 | 158 | 21 | 3 | 8c7108f2c40d97a317762ba0b8eca76542b2ebaf | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 5.71e-05 | 161 | 21 | 3 | 9466b8658244116f8d21f2f88fb8c2d184b1bdf2 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 5.71e-05 | 161 | 21 | 3 | 133b4fadb499e842c19f573f9cf09ce08c1d4813 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 5.71e-05 | 161 | 21 | 3 | cb177ca10d848d0e25399ab5ebfcde1071fb94c2 | |
| ToppCell | PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 5.81e-05 | 162 | 21 | 3 | 96c6e94a10b124a1d25dcd705ec5aaa8609c1089 | |
| ToppCell | PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.03e-05 | 164 | 21 | 3 | 5e5bd81414ea2d64f73cdef19a0a78c17bec8c18 | |
| ToppCell | PND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.03e-05 | 164 | 21 | 3 | f13b8d9b7f42193f333d9a77571a1dde6bbb48d8 | |
| ToppCell | PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.03e-05 | 164 | 21 | 3 | 4cfc9f92e49f86d3639e018b35b6a60dc62f494a | |
| ToppCell | PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.03e-05 | 164 | 21 | 3 | 7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6 | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.14e-05 | 165 | 21 | 3 | 347b59aa625a8a960828b8620824d8ac48990e07 | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.14e-05 | 165 | 21 | 3 | 1890f9c33b0c5b381d57f97042da2610a093a6de | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.14e-05 | 165 | 21 | 3 | 507c89ece0a336b8e9c65b79889a714e17ddca27 | |
| ToppCell | PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 6.14e-05 | 165 | 21 | 3 | 39a25be081a5d59c7cf107a997d352793d5025fb | |
| ToppCell | facs-Diaphragm-Limb_Muscle-18m-Lymphocytic-B_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.06e-05 | 173 | 21 | 3 | a693772987f1baee533dd0bd285a3c7b5619a73b | |
| ToppCell | pdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells) | 9.32e-05 | 190 | 21 | 3 | b05db0de9b6ae01dd30074453f7de44f7397631e | |
| Drug | Zonisamide | 1.26e-09 | 17 | 21 | 4 | DB00909 | |
| Drug | AC1L1MOZ | 9.26e-09 | 27 | 21 | 4 | CID000031958 | |
| Drug | APETx1, Anthopleura elegantissima | 1.35e-08 | 6 | 21 | 3 | ctd:C475726 | |
| Drug | tocainide | 1.44e-08 | 30 | 21 | 4 | CID000038945 | |
| Drug | lamotrigine | 6.00e-08 | 116 | 21 | 5 | CID000003878 | |
| Drug | pilsicainide | 8.51e-08 | 46 | 21 | 4 | CID000004820 | |
| Drug | bepridil | 9.08e-08 | 126 | 21 | 5 | CID000002351 | |
| Drug | lidocaine | 2.99e-07 | 160 | 21 | 5 | CID000003676 | |
| Drug | AC1L1CQC | 3.49e-07 | 65 | 21 | 4 | CID000002012 | |
| Drug | mexiletine | 3.71e-07 | 66 | 21 | 4 | CID000004178 | |
| Drug | disopyramide | 3.71e-07 | 66 | 21 | 4 | CID000003114 | |
| Drug | gabapentin | 3.92e-07 | 169 | 21 | 5 | CID000003446 | |
| Drug | dibucaine | 4.19e-07 | 68 | 21 | 4 | CID000003025 | |
| Drug | riluzole | 4.54e-07 | 174 | 21 | 5 | CID000005070 | |
| Drug | flecainide | 4.99e-07 | 71 | 21 | 4 | CID000003355 | |
| Drug | NSC7524 | 5.67e-07 | 182 | 21 | 5 | CID000005657 | |
| Drug | diprafenone | 6.49e-07 | 19 | 21 | 3 | CID000071249 | |
| Drug | Hexylcaine | 8.10e-07 | 2 | 21 | 2 | DB00473 | |
| Drug | Flecainide | 8.10e-07 | 2 | 21 | 2 | DB01195 | |
| Drug | Phenytoin | 8.10e-07 | 2 | 21 | 2 | DB00252 | |
| Drug | phenytoin | 1.41e-06 | 219 | 21 | 5 | CID000001775 | |
| Drug | AC1NT1AF | 1.54e-06 | 25 | 21 | 3 | CID005322157 | |
| Drug | Pirmenolum | 1.73e-06 | 26 | 21 | 3 | CID000004853 | |
| Drug | propafenone | 1.83e-06 | 98 | 21 | 4 | CID000004932 | |
| Drug | nefopam | 1.95e-06 | 27 | 21 | 3 | CID000004450 | |
| Drug | PbTx-1 | 1.95e-06 | 27 | 21 | 3 | CID006437089 | |
| Drug | isradipine | 1.98e-06 | 100 | 21 | 4 | CID000003784 | |
| Drug | paraben | 2.18e-06 | 28 | 21 | 3 | CID000007175 | |
| Drug | Dibucaine | 2.43e-06 | 3 | 21 | 2 | DB00527 | |
| Drug | N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide | 2.43e-06 | 3 | 21 | 2 | ctd:C561228 | |
| Drug | NSC93767 | 3.30e-06 | 32 | 21 | 3 | CID000005658 | |
| Drug | 5-hydroxypropafenone | 3.97e-06 | 34 | 21 | 3 | CID000107927 | |
| Drug | hydrochlorothiazide | 4.10e-06 | 120 | 21 | 4 | CID000003639 | |
| Drug | Lidocaine | 4.86e-06 | 4 | 21 | 2 | DB00281 | |
| Drug | benzocaine | 5.15e-06 | 37 | 21 | 3 | CID000002337 | |
| Drug | aprindine | 5.59e-06 | 38 | 21 | 3 | CID000002218 | |
| Drug | S-ropivacaine | 6.54e-06 | 40 | 21 | 3 | CID000071273 | |
| Drug | AC1NDZBZ | 7.05e-06 | 41 | 21 | 3 | CID004634042 | |
| Drug | spiradoline | 1.00e-05 | 46 | 21 | 3 | CID000005620 | |
| Drug | procaine | 1.07e-05 | 153 | 21 | 4 | CID000004914 | |
| Drug | indoxacarb | 1.21e-05 | 49 | 21 | 3 | CID000107720 | |
| Drug | fenpropathrin | 1.21e-05 | 6 | 21 | 2 | ctd:C044267 | |
| Drug | amiodarone | 1.28e-05 | 160 | 21 | 4 | CID000002156 | |
| Drug | AC1NSN3X | 1.63e-05 | 54 | 21 | 3 | CID005366189 | |
| Drug | carbamazepine | 1.99e-05 | 179 | 21 | 4 | CID000002554 | |
| Drug | triamterene | 2.02e-05 | 58 | 21 | 3 | CID000005546 | |
| Drug | RH 1 | 2.13e-05 | 59 | 21 | 3 | CID000394347 | |
| Drug | Cocaine | 2.26e-05 | 8 | 21 | 2 | DB00907 | |
| Drug | 2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate | 2.26e-05 | 8 | 21 | 2 | ctd:C489827 | |
| Drug | zonisamide | 2.47e-05 | 62 | 21 | 3 | CID000005734 | |
| Drug | procainamide | 2.52e-05 | 190 | 21 | 4 | CID000004913 | |
| Drug | propofol | 2.57e-05 | 191 | 21 | 4 | CID000004943 | |
| Drug | saxitoxin | 2.85e-05 | 65 | 21 | 3 | CID000037165 | |
| Drug | Mexiletine | 2.91e-05 | 9 | 21 | 2 | ctd:D008801 | |
| Drug | cyclaine | 2.91e-05 | 9 | 21 | 2 | CID000010770 | |
| Drug | resiniferatoxin | 2.98e-05 | 66 | 21 | 3 | CID000104826 | |
| Drug | GBR 12909 | 3.41e-05 | 69 | 21 | 3 | CID000003455 | |
| Drug | T2755 | 3.71e-05 | 71 | 21 | 3 | CID000005514 | |
| Drug | imide | 4.20e-05 | 74 | 21 | 3 | CID000443040 | |
| Drug | 1, 3-diallylurea | 4.20e-05 | 74 | 21 | 3 | CID000074537 | |
| Drug | isofagomine | 4.38e-05 | 75 | 21 | 3 | CID000447607 | |
| Drug | diphenhydramine | 4.38e-05 | 75 | 21 | 3 | CID000003100 | |
| Drug | quindine | 4.38e-05 | 219 | 21 | 4 | CID000001065 | |
| Drug | bupropion | 5.51e-05 | 81 | 21 | 3 | CID000000444 | |
| Drug | Sodium | 6.14e-05 | 84 | 21 | 3 | ctd:D012964 | |
| Drug | verapamil | 6.92e-05 | 490 | 21 | 5 | CID000002520 | |
| Drug | Verapamil | 9.65e-05 | 16 | 21 | 2 | DB00661 | |
| Drug | trimethoprim | 1.00e-04 | 99 | 21 | 3 | CID000005578 | |
| Drug | tetrapentylammonium | 1.09e-04 | 17 | 21 | 2 | CID000017248 | |
| Drug | isoflurane | 1.12e-04 | 279 | 21 | 4 | CID000003763 | |
| Drug | pyraclofos | 1.23e-04 | 106 | 21 | 3 | CID000093460 | |
| Drug | Scorpion Venoms | 1.23e-04 | 18 | 21 | 2 | ctd:D012604 | |
| Drug | Imipenem | 1.23e-04 | 18 | 21 | 2 | ctd:D015378 | |
| Drug | moricizine | 1.23e-04 | 18 | 21 | 2 | CID000034632 | |
| Drug | GTP[S] | 1.67e-04 | 591 | 21 | 5 | CID000001764 | |
| Drug | AC1L9JS4 | 2.00e-04 | 125 | 21 | 3 | CID000446532 | |
| Drug | bupivacaine | 2.00e-04 | 125 | 21 | 3 | CID000002474 | |
| Drug | MgSO4.7H2O | 2.40e-04 | 25 | 21 | 2 | CID000024843 | |
| Drug | Pyrazinamide | 2.80e-04 | 27 | 21 | 2 | ctd:D011718 | |
| Drug | clenbuterol | 2.91e-04 | 142 | 21 | 3 | CID000002783 | |
| Drug | DPI 201-106 | 3.02e-04 | 28 | 21 | 2 | CID000005190 | |
| Drug | encainide | 3.02e-04 | 28 | 21 | 2 | CID000048040 | |
| Drug | salbutamol | 3.16e-04 | 146 | 21 | 3 | CID000002083 | |
| Drug | decamethrin | 3.16e-04 | 146 | 21 | 3 | ctd:C017180 | |
| Drug | cyfluthrin | 3.24e-04 | 29 | 21 | 2 | ctd:C052570 | |
| Drug | oxcarbazepine | 3.47e-04 | 30 | 21 | 2 | CID000034312 | |
| Drug | willardine | 3.95e-04 | 32 | 21 | 2 | CID000005123 | |
| Drug | dihydrochloride | 4.05e-04 | 159 | 21 | 3 | CID000070978 | |
| Drug | NSC15627 | 4.47e-04 | 34 | 21 | 2 | CID000002073 | |
| Drug | toluene | 5.36e-04 | 175 | 21 | 3 | CID000001140 | |
| Drug | fenfluramine | 5.63e-04 | 178 | 21 | 3 | CID000003337 | |
| Drug | tetradotoxin | 5.72e-04 | 428 | 21 | 4 | CID000020382 | |
| Drug | ranolazine | 5.88e-04 | 39 | 21 | 2 | CID000056959 | |
| Drug | strychnine HCl | 5.91e-04 | 181 | 21 | 3 | CID000005304 | |
| Drug | Tetrodotoxin | 6.19e-04 | 40 | 21 | 2 | ctd:D013779 | |
| Drug | heptanol | 6.82e-04 | 42 | 21 | 2 | CID000008129 | |
| Drug | Carbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; MCF7; HT_HG-U133A | 7.13e-04 | 193 | 21 | 3 | 4173_DN | |
| Drug | Cimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HG-U133A | 7.34e-04 | 195 | 21 | 3 | 1884_UP | |
| Drug | AC1L1DNZ | 7.49e-04 | 44 | 21 | 2 | CID000002433 | |
| Drug | Azacyclonol [115-46-8]; Up 200; 15uM; HL60; HG-U133A | 7.68e-04 | 198 | 21 | 3 | 2020_UP | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 2.09e-14 | 10 | 20 | 5 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 2.09e-14 | 10 | 20 | 5 | DOID:0080422 (implicated_via_orthology) | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 6.57e-14 | 12 | 20 | 5 | DOID:0060170 (implicated_via_orthology) | |
| Disease | epilepsy (implicated_via_orthology) | 7.01e-08 | 163 | 20 | 5 | DOID:1826 (implicated_via_orthology) | |
| Disease | HYPOKALEMIC PERIODIC PARALYSIS, TYPE 1 | 4.36e-07 | 2 | 20 | 2 | 170400 | |
| Disease | Hypokalemic periodic paralysis, type 1 | 4.36e-07 | 2 | 20 | 2 | cv:C3714580 | |
| Disease | Hypokalemic periodic paralysis | 4.36e-07 | 2 | 20 | 2 | cv:C0238358 | |
| Disease | Hypokalemic periodic paralysis type 1 | 1.31e-06 | 3 | 20 | 2 | C3714580 | |
| Disease | Brugada ECG Pattern | 2.62e-06 | 4 | 20 | 2 | C1721096 | |
| Disease | Hypokalemic periodic paralysis | 2.62e-06 | 4 | 20 | 2 | C0238358 | |
| Disease | electrocardiography, PR interval | 9.15e-06 | 7 | 20 | 2 | EFO_0004327, EFO_0004462 | |
| Disease | hypokalemic periodic paralysis (implicated_via_orthology) | 1.22e-05 | 8 | 20 | 2 | DOID:14452 (implicated_via_orthology) | |
| Disease | supraventricular ectopy | 1.57e-05 | 9 | 20 | 2 | EFO_0009277 | |
| Disease | Congenital myopathy (disorder) | 2.87e-05 | 12 | 20 | 2 | C0270960 | |
| Disease | Brugada Syndrome 1 | 3.39e-05 | 13 | 20 | 2 | C4551804 | |
| Disease | T wave morphology measurement | 3.95e-05 | 14 | 20 | 2 | EFO_0008398 | |
| Disease | P wave duration | 4.56e-05 | 15 | 20 | 2 | EFO_0005094 | |
| Disease | Romano-Ward Syndrome | 5.21e-05 | 16 | 20 | 2 | C0035828 | |
| Disease | Brugada syndrome | 7.41e-05 | 19 | 20 | 2 | MONDO_0015263 | |
| Disease | anxiety disorder (implicated_via_orthology) | 1.00e-04 | 22 | 20 | 2 | DOID:2030 (implicated_via_orthology) | |
| Disease | Brugada Syndrome (disorder) | 1.19e-04 | 24 | 20 | 2 | C1142166 | |
| Disease | cardiovascular age measurement | 1.75e-04 | 29 | 20 | 2 | EFO_0803380 | |
| Disease | heart function measurement | 2.42e-04 | 34 | 20 | 2 | EFO_0004311 | |
| Disease | QRS complex, QRS duration | 4.25e-04 | 45 | 20 | 2 | EFO_0005054, EFO_0005055 | |
| Disease | TPE interval measurement | 5.67e-04 | 52 | 20 | 2 | EFO_0004644 | |
| Disease | abdominal adipose tissue measurement | 5.89e-04 | 53 | 20 | 2 | EFO_0803316 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| LNLQFLLVFLCTFMQ | 721 | P41180 | |
| IFALLNAFQGFFILL | 636 | Q8IZF3 | |
| FGTNNLLRFQLLMKL | 306 | Q2VYF4 | |
| MNQILHILFVFLPFL | 241 | Q63HM2 | |
| QLNELLLFAVGFIMA | 196 | P47881 | |
| MGTQALQGFLFLLFL | 1 | Q8NCW0 | |
| NMGAKFALFQVLLIL | 251 | Q86UW1 | |
| LFLFIVIFALLGMQL | 566 | Q13698 | |
| FNLLLQALFLIQGMF | 176 | O14681 | |
| LQNLIMGLFLLFFVL | 391 | Q9H222 | |
| LQALGSNIFLLQMFI | 371 | Q96S37 | |
| FILQNLGLLFGFAIM | 801 | Q9ULF5 | |
| GTLVFLFLNLIQINM | 136 | Q9NYV9 | |
| LLDLNEKQMIFFLNG | 431 | Q96DX4 | |
| ALFNIGLLLFLVMFI | 1481 | P35499 | |
| ALFNIGLLLFLVMFI | 1656 | Q14524 | |
| FALIGLQLFMGNLRN | 261 | Q9NY46 | |
| FALIGLQLFMGNLRN | 261 | P35498 | |
| ALFNIGLLLFLVMFI | 1606 | Q9Y5Y9 | |
| MTIFLVFLNGLAQLL | 901 | O95427 | |
| SNNFYMGLLLLVLFL | 691 | Q8TDI7 |